keyword
MENU ▼
Read by QxMD icon Read
search

Liver biliary tumor

keyword
https://www.readbyqxmd.com/read/29350267/modern-work-up-and-extended-resection-in-perihilar-cholangiocarcinoma-the-amc-experience
#1
REVIEW
F Rassam, E Roos, K P van Lienden, J E van Hooft, H J Klümpen, G van Tienhoven, R J Bennink, M R Engelbrecht, A Schoorlemmer, U H W Beuers, J Verheij, M G Besselink, O R Busch, T M van Gulik
AIM: Perihilar cholangiocarcinoma (PHC) is a challenging disease and requires aggressive surgical treatment in order to achieve curation. The assessment and work-up of patients with presumed PHC is multidisciplinary, complex and requires extensive experience. The aim of this paper is to review current aspects of diagnosis, preoperative work-up and extended resection in patients with PHC from the perspective of our own institutional experience with this complex tumor. METHODS: We provided a review of applied modalities in the diagnosis and work-up of PHC according to current literature...
January 19, 2018: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29350068/primary-liver-cancers-part-1-histopathology-differential-diagnoses-and-risk-stratification
#2
Kun Jiang, Sameer Al-Diffhala, Barbara A Centeno
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the 2 most common primary malignant liver tumors, with hepatocellular and bile ductular differentiation, respectively. This article reviews the key histopathological findings of these 2 primary liver cancers and includes a review of the role of ancillary testing for differential diagnosis, risk stratification according to the American Joint Committee on Cancer (AJCC) staging recommendation, and a review of precancerous lesions. A literature review was conducted to identify articles with information relevant to precancerous precursors, current histopathological classification, ancillary testing, and risk stratification of primary malignant liver tumors...
January 2018: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/29344901/imaging-characteristics-and-first-experience-of-68ga-thp-psma-a-novel-probe-for-rapid-kit-based-ga-68-labeling-and-pet-imaging-comparative-analysis-with-68ga-psma-i-t
#3
Thorsten Derlin, Sebastian Schmuck, Cathleen Juhl, Steffi Teichert, Johanna Zörgiebel, Hans-Jürgen Wester, Sophie M Schneefeld, Almut C A Walte, James T Thackeray, Tobias L Ross, Frank M Bengel
PURPOSE: [68Ga]Trishydroxypyridinone (THP)-prostate-specific membrane antigen (PSMA) is a novel tracer that can be labeled in one step by cold reconstitution of a kit with unprocessed generator eluate, targeting PSMA via the lysine-urea-glutamate (KuE) motif. The aim of this study was to evaluate the human imaging characteristics of [68Ga]THP-PSMA. PROCEDURES: [68Ga]THP-PSMA positron emission tomography (PET)/x-ray computed tomography (CT) was performed in 25 patients with biochemical recurrence after radical prostatectomy for prostate cancer...
January 17, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29324681/ppoma-review-epidemiology-aetiopathogenesis-prognosis-and-treatment
#4
REVIEW
Thais Ligiero Braga, Ralph Santos-Oliveira
Generally, pancreatic polypeptide-secreting tumor of the distal pancreas (PPoma) is classified as a rare tumor, and may occur sporadically or be associated in families or with multiple endocrine neoplasia type 1 (NEM 1). It grows slowly, reaching large dimensions at the time of diagnosis and the symptomatology is fundamentally due to the mass effect, causing either non-specific abdominal pain or symptoms suggestive of obstruction of the pancreatic or biliary duct. Therefore, when detected, they are usually malignant, with metastases mainly in the liver...
January 11, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29318905/multiparametric-mri-for-early-detection-of-diffuse-liver-disease-an-interview-with-david-breen
#5
David J Breen
David J Breen is Associate Professor of Radiology and previous Clinical Director of Radiology at University Hospital Southampton. His interests are in abdominal imaging and intervention, particularly of hepato-pancreato-biliary (HPB)and renal disease. He has a major interest in image-guided tumor ablation and improving outcomes from these procedures. He has previously served as Vice Chair of the NHS England Clinical Reference Group in Interventional Radiology and for the NIHR/NCRN Upper GI Clinical Studies Group...
January 10, 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29303514/depletion-of-s100a4-stromal-cells-does-not-prevent-hcc-development-but-reduces-the-stem-cell-like-phenotype-of-the-tumors
#6
Jingjing Jiao, Álvaro González, Heather L Stevenson, Mihai Gagea, Hikaru Sugimoto, Raghu Kalluri, Laura Beretta
There is a pressing need for the development of novel approaches to treat and prevent hepatocellular carcinoma (HCC). The S100 calcium-binding protein S100A4 is associated with poor prognosis and metastasis in several human cancers. In addition, a role for S100A4 in modulating cancer-initiating cells stemness properties was recently proposed in head and neck and gastric cancers. Whether S100A4+ stromal cells contribute to tumor onset remains, however, an unanswered question. To address that question, we generated a new mouse model allowing for the depletion of S100A4+ cells in a mouse model of HCC with stemness properties, by crossing mice with hepatic deletion of phosphatase and tensin homolog (PTEN) with mice expressing viral thymidine kinase under the control of S100A4 promoter...
January 5, 2018: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/29290661/are-liver-nested-stromal-epithelial-tumors-always-low-aggressive
#7
Tania Meletani, Luca Cantini, Andrea Lanese, Daniele Nicolini, Alessia Cimadamore, Andrea Agostini, Giulia Ricci, Stefania Antognoli, Alessandra Mandolesi, Maria Guido, Rita Alaggio, Gian Marco Giuseppetti, Marina Scarpelli, Marco Vivarelli, Rossana Berardi
Nested stromal-epithelial tumor (NSET) is a non-hepatocytic and non-biliary tumor of the liver consisting of nests of epithelial and spindled cells with associated myofibroblastic stroma and variable intra-lesional calcification and ossification, which represents a very rare and challenging disease. Most of the reported cases have been treated with surgery, obtaining a long survival outcome. Here, we report the case of a 31-year-old Caucasian man who underwent surgery at our institution for a large, lobulated, multinodular mass of the right hemi-liver...
December 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29285861/biliary-versus-thyroid-like-a-tale-of-two-morphologies
#8
Sharon J Song, Kathleen Montone, Kristen Stashek, Rashmi Tondon
Pictured here is a portacaval lymph node biopsy from a 72-year-old man with an 11.9 cm liver mass and several enlarged surrounding lymph nodes. The node was involved by a tumor with two distinct morphologies-one area resembling a primary pancreaticobiliary tumor (Figure 1) and another mimicking a thyroid follicular carcinoma with microfollicles containing brightly eosinophilic, colloid-like secretions (Figure 2). Immunohistochemistry showed the neoplastic cells to stain strongly with CK7 and CK19, with patchy positivity for CK20...
December 28, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29285386/scalp-recurrence-of-cholangiocarcinoma-after-curative-hepatectomy-a-report-of-two-cases
#9
Enver Kunduz, Kursat Rahmi Seri N, Mesut Seker
Cholangiocarcinomas are the second most common primary liver malignancies. The lymphatics are the common route of metastatic spread for cholangiocarcinomas. The most frequent sites of metastasis are the liver, abdominal lymph nodes, peritoneum and lungs. Cutaneous metastasis of cholangiocarcinoma is rare, and most commonly occurs following percutaneous biliary drainage. Brain or skull metastases from this tumor are uncommon. However, these rare metastatic lesions may occasionally be the first disease manifestation, although scalp recurrence following curative treatment is uncommon...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29262510/-a-prospective-pilot-study-of-combined-intra-operative-radiotherapy-for-centrally-located-hepatocellular-carcinomas
#10
Y H Liu, L M Wang, J X Wu, W Q Rong, F Wu, M H Li, Y Zhang, S T Lin, Y L Zheng, Q F Feng
Objective: To carry out a prospective cohort study of combined intra-operative radiotherapy for centrally located hepatocellular carcinomas (HCC) and to observe the safety and postoperative complications. Methods: A total of 79 patients with centrally located HCC who underwent hepatectomy were divided into two groups: experimental group (combined with targeted intra-operative radiotherapy, 32 cases) and control group (single surgical operation, 47 cases). Patients in the experimental group received intra-operative electron radiotherapy after tumor resection, while patients in the control group received to intra-operative electron radiotherapy...
December 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29226038/pencil-beam-scanning-proton-therapy-for-rhabdomyosarcoma-of-the-biliary-tract
#11
Luke Pater, Brian Turpin, Anthony Mascia
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood with 250-350 cases diagnosed annually in the United States. Biliary tract rhabdomyosarcoma is rare, representing <1% of the RMS cases. Due to its location, resection is clinically challenging, and functional complications exist and persist from biliary obstruction. The anatomical location of this tumor presents both opportunities and challenges for pencil beam scanning proton therapy. Proton therapy offers a dosimetric and clinical advantage by sparing the healthy liver, stomach, contra-lateral kidney and bowel...
October 5, 2017: Curēus
https://www.readbyqxmd.com/read/29224266/-application-of-liver-three-dimensional-visualization-technologies-in-the-treatment-planning-of-hepatic-malignant-tumor
#12
P P Li, Z H Wang, G Huang, Z P Huang, Y Li, J S Ni, H Liu, C H Fang, W P Zhou
Objective: To discuss the application of three dimentional(3D)visualization technologies in treatment plan of hepatic malignant tumor. Methods: The clinical data of 300 patients with liver malignant tumor who received treatment from January 2016 to January 2017 in the Third Department of Hepatic Surgery of Eastern Hepatobiliary Surgery Hospital was retrospectively analyzed in this study, including 221 male and 79 female patients aged from 7 to 76 years with median age of 54 years. The median height was 168 cm (115-183 cm), the median weight was 65 kg (20-105 kg) and the median tumor volume was 142 ml (23-2 493 ml)...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29206089/papillomatosis-of-the-biliary-tree-and-gallbladder-successful-treatment-with-repeated-resection-and-liver-transplant
#13
Vor Luvira, Ake Pugkhem, Vajarabhongsa Bhudhisawasdi, Thong-Ueb Uttaravichien, Anan Sripanuskul, Jongruk Pongskul, Chawalit Pairojkul
Intraductal papillary neoplasm of the bile duct is now considered to be a specific type of bile duct tumor. The progenitor cells of intraductal papillary neoplasms of the bile duct are located in the peribiliary gland, which are distributed along the intrahepatic bile duct, extrahepatic bile duct, and gallbladder; therefore, these neoplasms could arise in any area. The mainstay of treatment for patients with intraductal papillary neoplasm of the bile duct is complete surgical resection. Neoplasms involving both lobes of the liver can only be treated with liver transplant...
December 5, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29203074/microscopic-biliary-and-perineural-invasion-and-clinical-outcome-after-neoadjuvant-bevacizumab-based-chemotherapy-and-liver-resection-in-patients-with-colorectal-liver-metastases
#14
Judith Stift, Alexandra Graf, Christoph Schwarz, Dietmar Tamandl, Patrick Starlinger, Merima Herac, Andrea Beer, Friedrich Wrba, Martin Bodingbauer, Klaus Kaczirek, Stefan Stremitzer
BACKGROUND: The value of microscopic biliary and perineural invasion as prognostic biomarkers in patients with resectable colorectal liver metastases (CLM) who undergo neoadjuvant chemotherapy and liver resection is still unclear. This retrospective study was performed to elucidate this issue. METHODS: Histologic slides of resected CLM of patients who underwent neoadjuvant bevacizumab-based chemotherapy and liver resection were investigated with respect to biliary and perineural invasion...
November 26, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29192742/biliary-tract-rhabdomyosarcoma-a-report-from-the-soft-tissue-sarcoma-committee-of-the-associazione-italiana-ematologia-oncologia-pediatrica
#15
Katia Perruccio, Valerio Cecinati, Angela Scagnellato, Massimo Provenzi, Giuseppe Maria Milano, Eleonora Basso, Carla Manzitti, Giovanni Cecchetto, Rita Alaggio, Martina Di Martino, Amalia Schiavetti, Fraia Melchionda, Maria Carmen Affinita, Stefano Chiaravalli, Lucia Miglionico, Rita Balter, Angela Tamburini, Gianni Bisogno, Andrea Ferrari
INTRODUCTION: Rhabdomyosarcoma is a soft tissue malignant musculoskeletal tumor frequent in children. Biliary duct localization is extremely rare, but it is the most common cause of malignant obstructive jaundice in pediatric patients. METHODS: This report describes a series of 10 patients under 18 years of age with biliary tract rhabdomyosarcoma who were enrolled, from 1979 to 2004, in 3 consecutive Italian pediatric cooperative protocols that had been drawn up by the Soft Tissue Sarcoma Committee of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)...
December 1, 2017: Tumori
https://www.readbyqxmd.com/read/29164423/successful-radical-surgical-resection-of-initially-unresectable-intrahepatic-cholangiocarcinoma-by-downsizing-chemotherapy-with-gemcitabine-plus-cisplatin-a-case-report
#16
Ryosuke Takayanagi, Shigetsugu Takano, Kensuke Sugiura, Hideyuki Yoshitomi, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Atsushi Kato, Masaru Miyazaki, Masayuki Ohtsuka
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a subtype of biliary tract cancer (BTC). Recently, downsizing chemotherapy has been applied to initially unresectable BTCs, including ICC. CASE PRESENTATION: We report a case of liver resection in a 23-year-old woman who was diagnosed with initially unresectable ICC attached to the inferior vena cava, with portal vein (PV) cavernous transformation. Positron emission tomography (PET) showed fluorodeoxyglucose (FDG) uptake in the para-aortic lymph nodes...
November 21, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29152476/early-recovery-pathway-for-hepatectomy-data-driven-liver-resection-care-and-recovery
#17
REVIEW
Susanne G Warner, Zeljka Jutric, Liana Nisimova, Yuman Fong
In recent years, great progress has been made toward safer hepatobiliary surgical interventions. This has resulted in more widely available treatments for patients who in the past were ineligible for curative resection of primary liver tumors, liver metastases, and advanced biliary tumors. However, the rise in procedures has seen increasingly heterogeneous perioperative management, yielding strikingly disparate outcomes. A number of groups have attempted to standardize perioperative care in an effort to create enhanced recovery pathways (ERPs) and provide clinicians with a dependable roadmap to success following hepatectomy...
October 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29147441/intrahepatic-biliary-metastasis-of-colonic-adenocarcinoma-a-case-report-with-immunohistochemical-analysis
#18
Keisuke Kawashima, Naoki Watanabe, Sho Tawada, Takahito Adachi, Makoto Yamada, Yusuke Kitoh, Tamotsu Takeuchi, Takuji Tanaka
Although intrabiliary metastasis of carcinoma in the liver is unusual, intraductal and/or intraepithelial spread of cancer cells along intrahepatic bile ducts is now well recognized as hepatic metastasis. However, several clinical and laboratory findings, including images, lead us to differentially diagnose from primary intrahepatic cholangiocarcinoma. We report here on a case of colonic adenocarcinoma that metastasized to the liver with spread along with the intrahepatic bile duct of S5/6 area. The patient was a 51-year-old man and clinically diagnosed liver metastasis of sigmoid colon cancer (tub2, pMP, ly1, v0, n0), which was diagnosed and treated by sigmoidectomy 7 years ago...
June 2017: World Journal of Oncology
https://www.readbyqxmd.com/read/29121977/intrahepatic-biliary-cystadenoma-mimicking-hydatid-cyst-of-liver-a-clinicopathologic-study-of-six-cases
#19
Zubair Ahmad, Nasir Uddin, Wasim Memon, Jamshid Abdul-Ghafar, Arsalan Ahmed
BACKGROUND: Intrahepatic biliary cystadenomas are rare hepatic neoplasms, which are usually cystic. These tumors are often misdiagnosed as simple liver cysts and hydatid cysts clinically and radiologically owing to nonspecific clinical and radiologic features. These tumors require complete resection, as recurrence and malignant transformation can occur following incomplete excision. It is essential that these tumors be diagnosed accurately so that they can be adequately excised. METHODS: Clinical and radiological features of six cases of biliary cystadenoma are described...
November 10, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29118691/vanishing-tumor-in-a-liver-graft-from-a-hepatitis-b-virus-surface-antigen-positive-donor
#20
Mayo Fuchino, Kazuto Tajiri, Masami Minemura, Toshiro Sugiyama
We report a case of vanishing tumor considered as inflammatory pseudotumor (IPT) found in the liver after living donor liver transplantation (LDLT) from a hepatitis B virus surface antigen-positive donor. The radiological findings were similar to those of hepatocellular carcinoma (HCC). However, the tumor disappeared completely within several months and was suggested to have been an IPT. IPT is known to be associated with biliary duct operation or biliary infection, and it can show various enhancement patterns in radiological studies, sometimes resembling HCC...
September 2017: Case Reports in Gastroenterology
keyword
keyword
65799
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"