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Pulmonary embolism severity index

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https://www.readbyqxmd.com/read/29675617/is-acute-pulmonary-embolism-more-severe-in-the-presence-of-obstructive-sleep-apnea-results-from-an-observational-cohort-study
#1
Dinah Konnerth, Florian Schwarz, Michael Probst, Martin Seidler, Tanja Wagner, Christian Faul, Wolfgang von Scheidt, Martin Schwaiblmair, Thomas M Berghaus
Obstructive sleep apnea (OSA) might influence disease severity in acute pulmonary embolism (PE). 253 survivors of acute PE were evaluated for sleep-disordered breathing by portable monitoring and nocturnal polysomnography. PE patients with an apnea-hypopnoea index (AHI) ≥ 15/h were significantly older (p < 0.001), had significantly impaired renal (p < 0.001) and left ventricular functions (p = 0.003), showed significantly elevated troponin I (p = 0.005) and D-dimer levels (p = 0...
April 19, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29577524/pulmonary-infarction-secondary-to-pulmonary-embolism-an-evolving-paradigm
#2
Marjan Islam, Jason Filopei, Matthew Frank, Navitha Ramesh, Stacey Verzosa, Madeline Ehrlich, Eric Bondarsky, Albert Miller, David Steiger
BACKGROUND AND OBJECTIVE: Pulmonary infarction (PI) from pulmonary embolism (PE) remains an entity of unclear aetiology. PI has been thought to occur in elderly patients with cardiopulmonary disease. We hypothesize younger patients without cardiopulmonary comorbidities are at highest risk. Our study aims to characterize PI clinically and radiographically, determine associated risk factors and determine their clinical significance. METHODS: We conducted a single-centre retrospective review of 367 consecutive patients with PE...
March 25, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29567899/autopsy-findings-in-an-atypical-case-of-occult-massive-fatal-pulmonary-embolism-in-a-backdrop-of-hyperhomocysteinemia
#3
Pratibha Misra, Arijit Kumar Ghosh, Aneeta Jassar
A 43-year-old apparently healthy male presented with fever and presyncope. He was suspected to have massive pulmonary thromboembolism based on the clinico-biochemical profile. Despite aggressive thrombolytic therapy, he succumbed to his illness within 12 h of admission. Postmortem examination showed massive pulmonary thromboembolism and hyperhomocysteinemia with low high-density lipoproteins (HDL) cholesterol with antemortem blood sample. Herein, we report autopsy findings in a rare case of a young male with occult massive pulmonary thromboembolism without deep vein thrombosis, who had an atypical clinical presentation and was found to have underlying hyperhomocysteinemia and decreased HDLc...
January 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29504991/delayed-retroperitoneal-arterial-hemorrhage-after-inferior-vena-cava-filter-deployment-a-case-report
#4
Yongzheng Wang, Haiyang Chang, Wujie Wang, Wei Wang, Bin Liu, Zheng Li, Yuliang Li
RATIONALE: Pulmonary embolization is a life-threatening condition. The deployment of inferior vena cava (IVC) filter is the first choice for preventing embolus from the lower extremity. However, IVC filter complications are rare but not to be neglected. Penetration of the arterial wall may result in catastrophic damages. This case report describes a woman who suffered from retroperitoneal hemorrhage after placement of an IVC filter due to a pulmonary embolization. Her filter was found to have penetrated the right lumbar artery and caused the massive bleeding...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29410163/management-of-low-risk-pulmonary-embolism-patients-without-hospitalization-the-low-risk-pulmonary-embolism-prospective-management-study
#5
Joseph Bledsoe, Scott Woller, Scott Stevens, Valerie Aston, Rich Patten, Todd Allen, Benjamin Horne, Lydia Dong, James Lloyd, Greg Snow, Troy Madsen, Gregory Elliott
BACKGROUND: The efficacy and safety of managing patients with low-risk pulmonary embolism (PE) without hospitalization requires objective data from US medical centers. We sought to determine the 90-day composite rate of recurrent symptomatic VTE, major bleeding events, and all-cause mortality among consecutive patients diagnosed with acute low-risk PE managed without inpatient hospitalization; and to measure patient satisfaction. METHODS: We performed a prospective cohort single-arm management study conducted from January 2013 to October 2016 in five EDs...
February 2, 2018: Chest
https://www.readbyqxmd.com/read/29387419/predicting-contrast-induced-nephropathy-after-ct-pulmonary-angiography-in-the-critically-ill-a-retrospective-cohort-study
#6
Kwok M Ho, Yusrah Harahsheh
Background: It is uncertain whether we can predict contrast-induced nephropathy (CIN) after CT pulmonary angiography (CTPA). This study compared the ability of a validated CIN prediction score with the Pulmonary Embolism Severity Index (PESI) in predicting CIN after CTPA. Methods: This cohort study involved critically ill adult patients who required a CTPA to exclude acute pulmonary embolism (PE). Patients with end-stage renal failure requiring dialysis were excluded...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29357196/bilateral-branch-pulmonary-artery-valve-implantation-in-repaired-tetralogy-of-fallot
#7
Neha Bansal, Daisuke Kobayashi, Thomas J Forbes, Wei Du, Jeffrey M Zerin, Aparna Joshi, Daniel R Turner
BACKGROUND: Transcatheter, bilateral branch pulmonary artery (PA) valve implantation is a novel treatment for patients with severe pulmonary insufficiency and oversized right ventricle (RV) outflow tract. There is scarce data on efficacy and safety of this approach. METHODS: This was a retrospective study of 8 patients with repaired tetralogy of fallot (TOF) who underwent bilateral branch PA valve implantation. Demographics, echocardiography, cardiac catheterization, and axial imaging data were reviewed...
April 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29349525/value-of-ct-pulmonary-angiography-to-predict-short-term-outcome-in-patient-with-pulmonary-embolism
#8
Ahmed M Osman, Emad H Abdeldayem
To evaluate the role of CT pulmonary angiography (CTPA) in the assessment of pulmonary embolism (PE) severity and the related CT cardiac changes, reflecting the clinical status of the patients and predicting the outcome. A prospective study of 184 patients presented with suspicious acute PE. All patients underwent CTPA followed by ECHO. Pulmonary artery obstructive index (PAOI) using Qanadli Score was calculated and cardiac changes recorded. The patients' outcome was followed up for 30 days. Only 150 patients completed the study; 26...
January 18, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29305675/efficacy-and-safety-of-outpatient-treatment-with-direct-oral-anticoagulation-in-pulmonary-embolism
#9
REVIEW
R Ghazvinian, A Gottsäter, J L Elf
Anticoagulant treatment of acute pulmonary embolism (PE) has traditionally been hospital-based. The lesser need for monitoring with the increasingly used direct acting oral anticoagulants (DOAC) in comparison to warfarin potentially facilitates outpatient treatment of PE with these drugs. This study aimed to evaluate efficacy and safety of outpatient treatment of PE with DOAC. We extracted data from the Swedish quality registry for patients on oral anticoagulation (AuriculA) for all 245 patients in the southernmost hospital region in Sweden (1...
February 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29298357/study-of-helical-flow-inducers-with-different-thread-pitches-and-diameters-in-vena-cava
#10
Ying Chen, Xiaoyan Deng, Xinying Shan, Yubin Xing
Pulmonary embolism is a severe, potentially life-threatening condition. Inferior vena cava filters have been used to prevent recurrent pulmonary embolisms. However, the build-up of thrombosis in vena cava filters after deployment presents a severe problem to patients. Previous studies proposed that filters with helical flow are beneficial and capable of alleviating this problem. In this study, the hemodynamic performances of four typical helical flow inducers in the vena cava are determined using computational fluid dynamics simulations (steady-state and pulsatile flow) and compared...
2018: PloS One
https://www.readbyqxmd.com/read/29276010/clinical-gestalt-versus-prognostic-scores-for-prognostication-of-patients-with-acute-symptomatic-pulmonary-embolism
#11
Carlos Andrés Quezada, Celia Zamarro, Vicente Gómez, Ina Guerassimova, Rosa Nieto, Esther Barbero, Diana Chiluiza, Deisy Barrios, Raquel Morillo, David Jiménez
BACKGROUND AND OBJECTIVE: To determine the accuracy of clinical gestalt to identify patients with acute symptomatic pulmonary embolism (PE) at low-risk for short-term complications. PATIENTS AND METHODS: This study included a total of 154 consecutive patients diagnosed with acute symptomatic PE in a tertiary university hospital. We compared the prognostic accuracy of the Pulmonary Embolism Severity Index (PESI), the simplified PESI (sPESI), and clinical gestalt of 1) 2senior physicians (one with and one without experience in the management of patients with PE), 2) a fourth-year resident of Pneumology, 3) a third-year resident of Pneumology, and 4) a second-year resident of Pneumology...
December 21, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/29243836/the-long-term-prognostic-value-of-highly-sensitive-cardiac-troponin-i-in-patients-with-acute-pulmonary-embolism
#12
Katherine Lee Chuy, Emad Uddin Hakemi, Tareq Alyousef, Geetanjali Dang, Rami Doukky
BACKGROUND: In patients with acute pulmonary embolism (PE), detectable levels of cardiac troponin I (cTnI) using a highly sensitive assay have been associated with increased in-hospital mortality. We sought to investigate the impact of detectable cTnI on long-term survival following acute PE. HYPOTHESIS: Detectable cTnI levels in patients presenting with acute PE predict increased long-term mortality following hospital discharge. METHODS: In a retrospective cohort study, we analyzed consecutive patients with confirmed acute PE and cTnI assay available from the index hospitalization...
December 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29242264/prognostic-value-of-right-ventricular-dilatation-in-patients-with-low-risk-pulmonary-embolism
#13
Benoit Côté, David Jiménez, Benjamin Planquette, Anne Roche, Jonathan Marey, Jean Pastré, Guy Meyer, Olivier Sanchez
The prognosis of multidetector computed tomography (MDCT) assessed right ventricular dilatation (RVD) is unclear in patients with pulmonary embolism (PE) and a simplified Pulmonary Embolism Severity Index (sPESI) of 0. We investigated in these patients whether MDCT-assessed RVD, defined by a right to left ventricular ratio (RV/LV) ≥0.9 or ≥1.0, is associated with worse outcomes.We combined data from three prospective cohorts of patients with PE. The main study outcome was the composite of 30-day all-cause mortality, haemodynamic collapse or recurrent PE in patients with sPESI of 0...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29226891/the-relationship-between-right-ventricular-outflow-tract-fractional-shortening-and-pulmonary-embolism-severity-index-in-acute-pulmonary-embolism
#14
Ekrem Şahan, Murat Karamanlıoğlu, Suzan Şahan, Murat Gül, Ahmet Korkmaz, Omaç Tüfekçioğlu
OBJECTIVE: Right ventricular (RV) functions are clinically important in acute pulmonary embolism (APE). Measurement of systolic function of the right ventricular outflow tract (RVOT) with echocardiography is a simple method to evaluate RV function. The aim of this study was to determine the relationship between RVOT systolic function and the Pulmonary Embolism Severity Index (PESI). METHODS: A total of 151 patients diagnosed with APE by pulmonary computed tomography angiography or ventilation/perfusion scintigraphy were included...
December 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29223985/external-validation-of-generic-and-cancer-specific-risk-stratification-tools-in-patients-with-pulmonary-embolism-and-active-cancer
#15
Erin R Weeda, Jonathan T Caranfa, Simon B Zeichner, Craig I Coleman, Elaine Nguyen, Christine G Kohn
Background: Numerous risk stratification tools exist to predict early post-pulmonary embolism (PE) mortality; however, few were specifically designed for use in patients with cancer. This study sought to evaluate the performance of 3 cancer-specific (RIETE, POMPE-C, and Font criteria) and 3 generic (Hestia, Pulmonary Embolism Severity Index [PESI], and Geneva prognostic score [GPS]) risk stratification tools for predicting 30-day post-PE mortality in patients with active cancer. Methods: We identified consecutive, adult, objectively confirmed patients with PE and active cancer presenting to our institution from November 2010 to January 2014...
December 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29184692/advanced-duodenal-neoplasia-and-carcinoma-in-familial-adenomatous-polyposis-outcomes-of-surgical-management
#16
Fábio Guilherme Campos, Carlos Augusto Real Martinez, Leonardo Alfonso Bustamante Lopez, Danilo Toshio Kanno, Sérgio Carlos Nahas, Ivan Cecconello
Background: In addition to the presence of neoplasia in the colon and rectum, patients with familial adenomatous polyposis (FAP) may develop numerous polyps and carcinoma within the upper gastrointestinal tract. Methods: The aim of the present paper was to review the incidence advanced duodenal polyposis or cancer and their surgical outcomes. A retrospective review of patients' records from our department was performed. Information was retrieved from a prospective collected data, including clinical (gender, age, family history), endoscopic [association with colorectal cancer (CRC), polyposis severity, age at diagnosis] and surgical management (age, time from the index surgery, type of procedure, morbidity)...
October 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29107493/association-between-body-mass-index-and-thirty-day-complications-after-total-knee-arthroplasty
#17
Jaiben George, Nicolas S Piuzzi, Mitchell Ng, Nipun Sodhi, Anton A Khlopas, Michael A Mont
BACKGROUND: Although previous studies have evaluated the effect of obesity on the outcomes of total knee arthroplasty (TKA), most considered obesity as a binary variable. It is important to compare different weight categories and consider body mass index (BMI) as a continuous variable to understand the effects of obesity across the entire range of BMI. Therefore, the objective of this study is to analyze the effect of BMI on 30-day readmissions and complications after TKA, considering BMI as both a categorical and a continuous variable...
October 6, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29080550/frequency-of-use-and-acceptability-of-clinical-prediction-rules-for-pulmonary-embolism-among-swiss-general-internal-medicine-residents
#18
N Faller, O Stalder, A Limacher, S Bassetti, J H Beer, D Genné, E Battegay, D Hayoz, J Leuppi, B Mueller, A Perrier, G Waeber, N Rodondi, D Aujesky
INTRODUCTION: Whether clinical prediction rules for pulmonary embolism are accepted and used among general internal medicine residents remains uncertain. We therefore evaluated the frequency of use and acceptability of the Revised Geneva Score (RGS) and the Pulmonary Embolism Severity Index (PESI), and explored which factors were associated with rule use. MATERIALS/METHODS: In an online survey among general internal medicine residents from 10 Swiss hospitals, we assessed rule acceptability using the Ottawa Acceptability of Decision Rules Instrument (OADRI) and explored the association between physician and training-related factors and rule use using mixed logistic regression models...
December 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29055740/percutaneous-balloon-kyphoplasty-for-treatment-of-very-severe-osteoporotic-vertebral-compression-fractures-a-case-controlled-study
#19
Jin Kyu Lee, Hae-Won Jeong, Il-Han Joo, Young-Il Ko, Chang-Nam Kang
BACKGROUND CONTEXT: There exists controversy regarding percutaneous balloon kyphoplasty (PBK) in patients with very severe osteoporotic vertebral compression fracture (vsOVCF). PURPOSE: The study was conducted to investigate the clinical and radiological outcomes of PBK for the treatment of vsOVCF compared with those of non-vsOVCF. STUDY DESIGN/SETTING: Retrospective, case controlled. PATIENT SAMPLE: 167 consecutive patients (210 vertebral bodies) who underwent PBK for OVCF between March 2010 and January 2015 were assessed...
October 18, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29036031/value-of-the-delta-neutrophil-index-for-predicting-28-day-mortality-in-patients-with-acute-pulmonary-embolism-in-the-emergency-department
#20
Taeyoung Kong, Yoo Seok Park, Hye Sun Lee, Sinae Kim, Jong Wook Lee, Gina Yu, Claire Eun, Je Sung You, Hyun Soo Chung, Incheol Park, Sung Phil Chung
PURPOSE: Acute pulmonary embolism (PE), frequently seen in the emergency department (ED), is a leading cause of cardiovascular morbidity and mortality. The delta neutrophil index (DNI) reflects the fraction of circulating immature granulocytes as a component of the systemic inflammatory response syndrome criteria. The pathogenesis of acute PE is significantly associated with inflammation. The aim of the study was to investigate the clinical usefulness of the DNI as a marker of severity in patients with acute PE admitted to the ED...
October 14, 2017: Shock
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