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Vein harvesting

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https://www.readbyqxmd.com/read/28524833/promoting-vasa-vasorum-neovascularization-of-vein-grafts-extenuates-hypoxia-of-the-wall-and-its-subsequent-influence-on-intimal-hyperplasia
#1
Rong-Jiang Zou, Zheng-Hua Wang, Chen-Xi Wang, Song Xue
BACKGROUND: The autologous saphenous vein is the most common conduit for coronary artery bypass grafting, but the vein graft disease will occur. This study used Matrigel basement membrane matrix with many different growth factors to promote vasa vasorum neovascularization and extenuate the hypoxia to improve remodeling. METHODS: This study observed the hypoxia and thickness of the vein grafts at different times. Normal veins and vein grafts with 15 min of ischemia one day postoperatively were harvested in the neck of rabbits...
June 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28507858/reconstructing-discontinuous-facial-defects-with-simultaneous-ulnar-perforator-free-flaps
#2
Carissa M Thomas, Mofiyinfolu Sokoya, Frederic W-B Deleyiannis
Multiple, simultaneous skin cancers of the face are common. This is the first description of reconstructing discontinuous facial defects (i.e., separate sites of the face) with simultaneous ulnar perforator flaps. The distinct innovations of this multiple flap design are the ability to restrict the harvest site to one extremity, to obtain vein and arterial grafts from the same extremity, and to create multiple flaps with minimal hirsutism and bulk. We present a case of a 57-year-old male with multiple basal cell carcinomas who underwent wide local excisions of the right upper lip and cheek and of the left lower eyelid and infraorbital cheek...
April 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28503843/the-volume-cost-and-outcomes-of-pancreatic-resection-in-a-regional-centre-in-new-zealand
#3
Neil Wylie, Phillip Hider, Delwyn Armstrong, Sanket Srinivasa, Michael Rodgers, Anna Brown, Jonathan Koea
BACKGROUND: The frequency, costs and outcome of pancreatic resection (both pancreaticoduodenectomy and distal pancreatectomy) were reviewed in our own institution and correlated with regional population growth as well as national resection rates and locations. METHODS: Demographic, pathological and outcome data on pancreaticoduodenectomy and distal pancreatectomy were obtained from a prospectively maintained database for the years 2005-2009 and 2010-2014. During this period, the catchment population grew from 460 000 to 567 000...
May 14, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28501131/microrna-203-promotes-liver-regeneration-after-partial-hepatectomy-in-cirrhotic-rats
#4
Xiao-Bo Chen, Xiao-Bo Zheng, Zhen-Xing Cai, Xian-Jian Lin, Ming-Qing Xu
BACKGROUND: Liver resection or partial hepatectomy (PH) is still the most commonly used therapeutic option for hepatocellular carcinoma (HCC) at present. However, the impaired regenerative ability induced by the accompanied liver cirrhosis is an important risk factor of posthepatectomy liver failure, and posthepatectomy liver failure is a feared complication that accounts for up to 75% of mortality after extensive liver resection. MicroRNA(miR)-203 is a tumor suppressor of HCC and may act as a positive intermediary in A20-enhanced interleukin (IL-6)/signal transducer and activator of transcription 3 (STAT3) pro-proliferative signals, which may promote liver regeneration after PH...
May 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28495542/endothelial-function-is-preserved-in-veins-harvested-by-either-endoscopic-or-surgical-techniques
#5
Adam R Wheeler, Daniel E Kendrick, Matt T Allemang, Andre F Gosling, Ann H Kim, Alfred Hausladen, Vikram S Kashyap
OBJECTIVES: Endoscopic vein harvest for lower extremity arterial bypass grafting has been questioned due to concern for endothelial damage during procurement. We sought to compare Nitric Oxide (NO)-mediated endothelial dependent relaxation (EDR) in vein segments harvested using open surgical (OH) versus endoscopic (EH) techniques. METHODS: Saphenous vein segments were harvested for lower extremity bypass, and a single, minimally handled section of saphenous vein, free of branches, was taken from the end of the graft...
May 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28486684/superior-vasodilation-of-human-pulmonary-vessels-by-vardenafil-compared-with-tadalafil-and-sildenafil-additive-effects-of-bosentan%C3%A2
#6
Michael Ried, Reiner Neu, Karla Lehle, Christian Großer, Tamas Szöke, Gunter Lang, Hans-Stefan Hofmann, Markus Hoenicka
OBJECTIVES: Pulmonary arterial hypertension is characterized by pulmonary vascular proliferation and remodelling, leading to a progressive increase in pulmonary arterial resistance. Vasodilator properties of 3 different phosphodiesterase (PDE)-5 inhibitors alone and in combination with an endothelin (ET) receptor antagonist were compared in an ex vivo model. METHODS: Segments of human pulmonary arteries (PAs) and pulmonary veins (PVs) were harvested from lobectomy specimens...
May 9, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28480318/assessment-of-regional-bone-tissue-perfusion-in-rats-using-fluorescent-microspheres
#7
Mohammad W Aref, Ethan Akans, Matthew R Allen
Disturbances in bone blood flow have been shown to have deleterious effects on bone properties yet there remain many unanswered questions about skeletal perfusion in health and disease, partially due to the complexity of measurement methodologies. The goal of this study was use fluorescent microspheres in rats to assess regional bone perfusion by adapting mouse-specific fluorescent microsphere protocol. Ten fifteen-week old Sprague Dawley rats were injected with fluorescent microspheres either via cardiac injection (n = 5) or via tail vein injection (n = 5)...
June 2017: Bone Reports
https://www.readbyqxmd.com/read/28475708/is-endoscopic-long-saphenous-vein-harvesting-equivalent-to-open-harvesting-technique-in-terms-of-graft-patency
#8
Amer Harky, Damian Balmforth, Alex Shipolini, Rakesh Uppal
A best evidence topic was written according to a structured protocol. The question addressed was whether endoscopic vein harvesting (EVH) is equivalent to open vein harvesting in terms of graft patency for patients undergoing coronary artery bypass surgery. A total of 417 articles were found using the reported search, of which 4 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these articles are tabulated...
May 5, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28473335/evaluation-of-autologous-skeletal-muscle-derived-factors-for-regenerative-medicine-applications
#9
M Yoshikawa, T Nakasa, M Ishikawa, N Adachi, M Ochi
OBJECTIVES: Regenerative medicine is an emerging field aimed at the repair and regeneration of various tissues. To this end, cytokines (CKs), growth factors (GFs), and stem/progenitor cells have been applied in this field. However, obtaining and preparing these candidates requires invasive, costly, and time-consuming procedures. We hypothesised that skeletal muscle could be a favorable candidate tissue for the concept of a point-of-care approach. The purpose of this study was to characterize and confirm the biological potential of skeletal muscle supernatant for use in regenerative medicine...
May 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28459400/-effects-of-hydrogen-sulfide-on-mitochondria-of-lung-in-rats-with-ali-induced-by-lipopolysaccharide
#10
Quansheng Du, Meng Zhang, Guofeng Li, Chao Wang, Nan Zhang, Jianxin Zhang
OBJECTIVE: To observe the effects of hydrogen sulfide (H2S) on structure and function of mitochondria of lung in rats with acute lung injury (ALI) induced by lipopolysaccharide (LPS). METHODS: Forty healthy male Sprague-Dawley (SD) rats were randomly divided into control group, LPS injury group, and low-, middle-, and high-dose NaHS groups, with 8 rats in each group. The rats in LPS injury group were given LPS 5 mg/kg via sublingual vein, and those in low-, middle-, and high-dose NaHS groups were challenged by LPS for 3 hours followed by intraperitoneally injection of 0...
January 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28457324/liver-autotransplantation-and-retrohepatic-vena-cava-reconstruction-for-alveolar-echinococcosis
#11
Hankui Hu, Bin Huang, Jichun Zhao, Wentao Wang, Qiang Guo, Yukui Ma
BACKGROUND: Alveolar echinococcosis (AE) is characterized by a slow-growing infiltrative neoplasm that is often unresectable by traditional methods because of strong adhesions and invasion to adjacent structures. We present our experience with liver autotransplantation and retrohepatic inferior vena cava (RHIVC) reconstruction using autogenous veins in patients with this end-stage parasitic disease. METHODS: Twelve patients with hepatic AE and extensive RHIVC, hepatic vein, and/or hilar invasion underwent ex vivo liver resection and RHIVC reconstruction using autogenous veins followed by autotransplantation in the West China Hospital of Sichuan University from 2013 to 2016...
April 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28456355/potential-mechanisms-of-vascular-thrombosis-after-microwave-ablation-in-an%C3%A2-in%C3%A2-vivo-liver
#12
Jason Chiang, Kwang Nickel, Randall J Kimple, Christopher L Brace
PURPOSE: To evaluate potential biologic and thermal mechanisms of the observed differences in thrombosis rates between hepatic vessels during microwave (MW) ablation procedures. MATERIALS AND METHODS: MW ablation antennae were placed in single liver lobes of 2 in vivo porcine liver models (n = 3 in each animal; N = 6 total) in the proximity of a large (> 5 mm) portal vein (PV) and hepatic veins (HVs). Each ablation was performed with 100 W for 5 minutes. Conventional ultrasound imaging and intravascular temperature probes were used to evaluate vessel patency and temperature changes during the ablation procedure...
April 26, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28453337/venous-bridge-arterial-grafting-for-thumb-replantation
#13
Eric R Wagner, Allen T Bishop, Alexander Y Shin
BACKGROUND: The purpose of this study is to describe a novel technique using an interposition vein graft for thumb replantation in these severe avulsion injuries. METHODS: From 2002 to 2012, 8 patients underwent interposition venous bridge grafting from the dorsal radial artery at the anatomic snuffbox to the ulnar digital artery of the thumb. All patients had a traumatic thumb amputation with a severe injury to the ulnar digital artery. The technique began with bony stabilization; the radial artery at the anatomic snuffbox is exposed, vein graft harvested, and microsurgical end-to-side (proximally) and end-to-end (distally) anastomoses are carried out...
May 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28446193/liver-morphometrics-and-metabolic-blood-profile-across-divergent-phenotypes-for-feed-efficiency-in-the-bovine
#14
Yuri Regis Montanholi, Livia Sadocco Haas, Kendall Carl Swanson, Brenda Lee Coomber, Shigeto Yamashiro, Stephen Paul Miller
BACKGROUND: Feed costs are a major expense in the production of beef cattle. Individual variation in the efficiency of feed utilization may be evident through feed efficiency-related phenotypes such as those related to major energetic sinks. Our objectives were to assess the relationships between feed efficiency with liver morphometry and metabolic blood profile in feedlot beef cattle. METHODS: Two populations (A = 112 and B = 45) of steers were tested for feed efficiency...
April 26, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28443569/can-a-small-intestine-segment-be-an-alternative-biological-conduit-for-peripheral-nerve-regeneration
#15
Mehmet S Arda, Emre A Koçman, Emre Özkara, Erdem Söztutar, Orhan Özatik, Aydan Köse, Cengiz Çetin
BACKGROUND: Autologous nerve grafts (ANG) are used to bridge peripheral nerve defects. Limited sources and donor site morbidity are the major problems of peripheral nerve grafts. Although various types of autologous grafts such as arteries, veins and muscles have been recommended, an ideal conduit has not been described yet. AIMS: The purpose of present study is to investigate the effectiveness of small intestinal conduit (SIC) for peripheral nerve defects. STUDY DESIGN: Animal experimentation...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28439192/bedside-vein-mapping-for-conduit-size-in-coronary-artery-bypass-surgery
#16
Frank Manetta, Pey-Jen Yu, Allan Mattia, John C Karaptis, Alan R Hartman
BACKGROUND AND OBJECTIVES: The greater saphenous vein has been used in coronary artery bypass grafting (CABG) for more than 50 years. Endoscopic vein harvesting has greatly reduced the morbidity associated with obtaining the vein, but the quality of the vein could not be assessed before its was exposed surgically or after the endoscopic procedure had been performed. This study was conducted to evaluate the accuracy of preoperative mapping of the greater saphenous vein at the bedside in assessing suitable conduit size for use in CABG...
April 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28433355/the-no-touch-saphenous-vein-graft-in-elderly-coronary-bypass-patients-with-multiple-comorbidities-is-a-promising-conduit-to-substitute-the-left-internal-thoracic-artery
#17
Ninos Samano, Håkan Geijer, Lennart Bodin, Mikael Arbeus, John D Mannion, Michael Dashwood, Domingos Souza
OBJECTIVES: We investigated the patency rates of no-touch saphenous vein grafts anastomosed to the left anterior descending artery compared with the left internal thoracic artery. Further, we compared the patency of no-touch vein grafts to the left anterior descending artery with the patency of no-touch vein grafts to other coronary arteries. METHODS: Of 2635 consecutive patients undergoing coronary artery bypass grafting between 2003 and 2008, 168 (6.3%) were given at least a saphenous vein graft to the left anterior descending artery to avoid harvesting complications in high-risk patients or in response to a left internal thoracic artery injury...
March 24, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28427135/-effects-of-allogeneic-bone-marrow-mesenchymal-stem-cells-on-polarization-of-peritoneal-macrophages-in-rats-with-sepsis
#18
Y H Zheng, B Xiong, Y Y Deng, W Lai, S Y Zheng, H N Bian, Z A Liu, Z F Huang, C W Sun, H H Li, H M Luo, L H Ma, H X Chen
Objective: To explore the effects of allogeneic bone marrow mesenchymal stem cells (BMSCs) on polarization of peritoneal macrophages isolated from rats with sepsis induced by endotoxin/lipopolysaccharide (LPS). Methods: (1) BMSCs were isolated, cultured and purified from 5 SD rats with whole bone marrow adherent method. The third passage of cells were collected for morphologic observation, detection of expressions of stem cell surface markers CD29, CD44, CD45, and CD90 with flow cytometer, and identification of osteogenic and adipogenic differentiation...
April 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28420464/-effect-of-combination-therapy-with-propofol-and-hydrogen-rich-saline-on-organ-damage-and-cytokines-in-a-murine-model-of-sepsis
#19
Yunchuan Hong, Hongguang Chen, Yonghao Yu, Keliang Xie
OBJECTIVE: To investigate the effect of combining propofol with hydrogen on organ damage and inflammation of sepsis in cecal ligation and puncture (CLP) mice model. METHODS: One hundred and forty male C57BL/6 mice were randomly divided into groups (n = 28): sham group, CLP group, propofol group, H2 group, and propofol and H2 group. The sepsis was induced by CLP operation. Mice in sham group did the same operation with ligation and puncture. The mice of propofol group and propofol and H2 group were given 50 mg/kg propofol through tail vein at 1 hour and 6 hours after CLP and the mice of H2 group and propofol and H2 group were given 5 mL/kg H2-rich saline i...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28420460/-bone-marrow-mesenchymal-stem-cells-modulated-the-inflammatory-response-by-regulating-the-expression-of-il-4-and-rage-products-in-the-rats-with-mods
#20
Xia Zhou, Guanghui Xiu, Yichao Zhu, Xiaolei Chen, Wei Xiong, Xinghua Pan, Jie Sun, Bin Ling
OBJECTIVE: To investigate the underlying mechanism of bone marrow mesenchymal stem cells (BMSC) modulating the inflammatory response during the multiple organ dysfunction syndrome (MODS), especially the expression of inflammatory cytokines, which will provide new theoretical and experimental basis of MODS in clinic. METHODS: BMSC of Sprague-Dawley (SD) rat (female, 4 weeks) was extracted and cultivated, and the 4th passage were used in experimental study. According to the random number table, 60 female SD rats were divided into three groups (n = 20 per group): sham group, MODS group, BMSC group...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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