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https://www.readbyqxmd.com/read/29457370/avian-metapneumovirus-subtype-c-in-wild-waterfowl-in-ontario-canada
#1
C M Jardine, E J Parmley, T Buchanan, L Nituch, D Ojkic
Avian metapneumovirus (aMPV) is an emerging poultry pathogen that has a significant economic impact on poultry production worldwide. The geographic range of the virus continues to expand, and wild birds have been implicated as reservoirs of aMPV that have the potential to spread the virus over long distances. Our objective was to determine the apparent prevalence of aMPV subtype C in wild waterfowl in Ontario, Canada. Wild waterfowl were captured in August and September, 2016 as part of routine migratory waterfowl population monitoring by the Ontario Ministry of Natural Resources and Forestry...
February 18, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29456585/neuroinflammation-and-neurohormesis-in-the-pathogenesis-of-alzheimer-s-disease-and-alzheimer-linked-pathologies-modulation-by-nutritional-mushrooms
#2
REVIEW
Angela Trovato Salinaro, Manuela Pennisi, Rosanna Di Paola, Maria Scuto, Rosalia Crupi, Maria Teresa Cambria, Maria Laura Ontario, Mario Tomasello, Maurizio Uva, Luigi Maiolino, Edward J Calabrese, Salvatore Cuzzocrea, Vittorio Calabrese
Human life develops and expands not only in time and space, but also in the retrograde permanent recollection and interweaving of memories. Therefore, individual human identity depends fully on a proper access to the autobiographical memory. Such access is hindered or lost under pathological conditions such as Alzheimer's disease, including recently associated oxidant pathologies, such as ocular neural degeneration occurring in glaucoma or neurosensorial degeneration occurring in Menière's disease. Oxidative stress and altered antioxidant systems have been suggested to play a role in the aetiology of major neurodegenerative disorders, and altered expression of genes sensing oxidative stress, as well as decreased cellular stress response mechanisms could synergistically contribute to the course of these oxidant disorders...
2018: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/29456067/revision-hip-arthroscopy-after-labral-reconstruction-using-iliotibial-band-autograft-surgical-findings-and-comparison-of-outcomes-with-labral-reconstructions-not-requiring-revision
#3
Renato Locks, Ioanna K Bolia, Hajime Utsunomiya, Karen K Briggs, Marc J Philippon
PURPOSE: To determine the causes of revision hip arthroscopy in patients who underwent labral reconstruction and to compare outcomes of these patients with patients who did not require a revision following reconstruction. METHODS: Patients who underwent revision hip arthroscopy after previous labral reconstruction from 2006 to 2014 were included. Patients with less than 2-year follow-up, preoperative joint space of ≤2 mm, or who underwent other reconstructive procedures at the time of labral reconstruction were excluded...
February 15, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29454821/mortality-in-single-fathers-compared-with-single-mothers-and-partnered-parents-a-population-based-cohort-study
#4
Maria Chiu, Farah Rahman, Simone Vigod, Cindy Lau, John Cairney, Paul Kurdyak
BACKGROUND: Single parent families, including families headed by single fathers, are becoming increasingly common around the world. Previous evidence suggests that single parenthood is associated with adverse health outcomes and increased mortality; however, most studies have focused on single mothers, with little known about the health of single fathers. This study aimed to examine mortality in a large population-based sample of Canadian single fathers compared with single mothers and partnered fathers and mothers...
February 14, 2018: Lancet. Public Health
https://www.readbyqxmd.com/read/29454556/validity-and-responsiveness-of-the-two-minute-walk-test-for-measuring-functional-recovery-after-total-knee-arthroplasty
#5
Aasis Unnanuntana, Pakpoom Ruangsomboon, Worawut Keesukpunt
BACKGROUND: The 2-minute walk test (2mwt) is a performance-based test that evaluates functional recovery after total knee arthroplasty (TKA). This study evaluated its validity compared with the modified Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Oxford Knee Score (OKS), modified Knee Score, Numerical Pain Rating Scale, and Timed Up and Go test, and its responsiveness in assessing functional recovery in TKA patients. METHODS: This prospective cohort study included 162 patients undergoing primary TKA between 2013 and 2015...
January 31, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29454487/a-cost-utility-analysis-of-transcatheter-versus-surgical-aortic-valve-replacement-for-the-treatment-of-aortic-stenosis-in-the-population-with-intermediate-surgical-risk
#6
Derrick Y Tam, Avery Hughes, Stephen E Fremes, Saerom Youn, Rebecca L Hancock-Howard, Peter C Coyte, Harindra C Wijeysundera
OBJECTIVE: Although transcatheter aortic valve implantation has been shown to be noninferior to surgical aortic valve replacement in patients with severe aortic stenosis at intermediate surgical risk, the cost-effectiveness of this strategy in this population is unknown. Our objective was to conduct a cost-utility analysis comparing transcatheter aortic valve implantation with surgical aortic valve replacement in the population with intermediate risk severe aortic stenosis. METHODS: A fully probabilistic Markov model with 30-day cycles was constructed from the Canadian third-party payer's perspective to estimate the difference in cost and effectiveness (measured as quality-adjusted life years) of transcatheter aortic valve implantation versus surgical aortic valve replacement for intermediate-risk patients over a lifetime time horizon, discounted at 1...
February 2, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29454336/change-in-physical-activity-level-and-clinical-outcomes-in-older-adults-with-knee-pain-a-secondary-analysis-from-a-randomised-controlled-trial
#7
Jonathan G Quicke, Nadine E Foster, Peter R Croft, Reuben O Ogollah, Melanie A Holden
BACKGROUND: Exercise interventions improve clinical outcomes of pain and function in adults with knee pain due to osteoarthritis and higher levels of physical activity are associated with lower severity of pain and higher levels of physical functioning in older adults with knee osteoarthritis in cross-sectional studies. However, to date no studies have investigated if change in physical activity level during exercise interventions can explain clinical outcomes of pain and function. This study aimed to investigate if change in physical activity during exercise interventions is associated with future pain and physical function in older adults with knee pain...
February 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29453648/supplemental-diagnosis-of-gyrodactylus-fairporti-van-cleave-1921-monogenea-from-1-month-old-black-bullhead-ameiurus-melas-in-riverside-pools-in-wisconsin
#8
Eric Leis, Russell Easy, David Cone
Samples of Gyrodactylus fairporti Van Cleave, 1921 from young-of-the-year black bullhead (Ameiurus melas) stranded in riverside pools of the Black River (La Crosse County,) WI, USA, are used to supplement the species diagnosis, including new details on the marginal hook sickles, the male copulatory organ (MCO), and 18S rRNA gene sequence data. The anchors of G. fairporti are relatively long and thin, 58.2 ± 1.2 μm in length; roots 15.5 ± 1.0 μm; shaft 38.1 ± 1.5 μm; point 31.3 ± 1.5 μm. The ventral bar is 19...
February 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29453190/testing-behavior-change-techniques-to-encourage-primary-care-physicians-to-access-cancer-screening-audit-and-feedback-reports-protocol-for-a-factorial-randomized-experiment-of-email-content
#9
Gratianne Vaisson, Holly O Witteman, Zachary Bouck, Caroline A Bravo, Laura Desveaux, Diego Llovet, Justin Presseau, Marianne Saragosa, Monica Taljaard, Shama Umar, Jeremy M Grimshaw, Jill Tinmouth, Noah M Ivers
BACKGROUND: Cancer Care Ontario's Screening Activity Report (SAR) is an online audit and feedback tool designed to help primary care physicians in Ontario, Canada, identify patients who are overdue for cancer screening or have abnormal results requiring follow-up. Use of the SAR is associated with increased screening rates. To encourage SAR use, Cancer Care Ontario sends monthly emails to registered primary care physicians announcing that updated data are available. However, analytics reveal that 50% of email recipients do not open the email and less than 7% click the embedded link to log in to their report...
February 16, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29452899/influence-of-dominant-as-compared-with-nondominant-side-symptoms-on-disabilities-of-the-arm-shoulder-and-hand-and-western-ontario-rotator-cuff-scores-in-patients-with-rotator-cuff-tendinopathy
#10
David Høyrup Christiansen, Lori Michener, Jean-Sébastien Roy
HYPOTHESIS AND BACKGROUND: The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and the Western Ontario Rotator Cuff (WORC) index are 2 widely used patient-reported questionnaires in individuals with rotator cuff (RC) tendinopathy. In contrast to the WORC index, for which the items are specific to the affected shoulder, the items of the DASH questionnaire assess the ability to perform activities regardless of the arm used. The objective of this study is to determine whether scores on the DASH questionnaire and WORC index are affected if the symptoms are on the dominant or nondominant side in individuals with RC tendinopathy...
February 13, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29450965/risk-of-early-onset-breast-cancer-among-women-exposed-to-thoracic-computed-tomography-in-pregnancy-or-early-postpartum
#11
Kirsteen R Burton, Alison L Park, Michael Fralick, Joel G Ray
BACKGROUND: The risk of breast cancer may be higher with direct exposure to ionizing radiation from thoracic computed tomography (CT) during pregnancy or postpartum. We evaluated the short-term risk of maternal breast cancer after exposure to thoracic CT during these periods. METHODS: We completed a retrospective population-based cohort study of all deliveries between 1995-2014 using universal health care databases in the province of Ontario, Canada. The main exposure was thoracic CT in pregnancy or ≤ 42 days postpartum...
February 16, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29450208/clinical-outcomes-after-microfracture-of-the-knee-midterm-follow-up
#12
Alexander E Weber, Philip H Locker, Erik N Mayer, Gregory L Cvetanovich, Annemarie K Tilton, Brandon J Erickson, Adam B Yanke, Brian J Cole
Background: Microfracture is a single-stage arthroscopic procedure used to treat small- and medium-sized cartilage defects, the clinical results of which have been mixed to date. Purpose: To retrospectively evaluate prospectively collected patient-reported outcomes (PROs) after microfracture as well as to determine patient-related and defect-related factors associated with clinical outcomes and which factors predict the need for additional surgery. Study Design: Case-control study; Level of evidence, 3...
February 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29449263/patterns-of-methadone-maintenance-treatment-provision-in-ontario-policy-success-or-pendulum-excess
#13
Paul Kurdyak, Binu Jacob, Juveria Zaheer, Benedikt Fischer
OBJECTIVE: To describe recent trends and patterns in methadone maintenance treatment (MMT) practice regionally and over time in the province of Ontario. DESIGN: Population-based descriptive study using health administrative data between September 1, 2011, and December 31, 2014. SETTING: Ontario. PARTICIPANTS: All active MMT-prescribing physicians and patients receiving MMT in the study period. MAIN OUTCOME MEASURES: Characteristics of MMT-prescribing physicians, including age, sex, specialty type, practice region, and practice volume; characteristics of patients receiving MMT, including age, sex, neighbourhood income, and region of residence...
February 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29448817/treating-severe-knee-osteoarthritis-with-combination-of-intra-osseous-and-intra-articular-infiltrations-of-platelet-rich-plasma-an-observational-study
#14
Mikel Sánchez, Diego Delgado, Orlando Pompei, Juan Carlos Pérez, Pello Sánchez, Ane Garate, Ane Miren Bilbao, Nicolás Fiz, Sabino Padilla
Objective Assessing the therapeutic effects of a combination of intra-articular and intra-osseous infiltrations of platelet-rich plasma (PRP) to treat severe knee osteoarthritis (KOA) using intra-articular injections of PRP as the control group. Design In this observational study, 60 patients suffering from severe KOA were treated with intra-articular infiltrations of PRP (IA group) or with a combination of intra-osseous and intra-articular infiltrations of PRP (IO group). Both groups were matched for sex, age, body mass index, and radiographic severity (III and IV degree according to Ahlbäck scale)...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29447253/combined-impairments-in-vision-hearing-and-cognition-are-associated-with-greater-levels-of-functional-and-communication-difficulties-than-cognitive-impairment-alone-analysis-of-interrai-data-for-home-care-and-long-term-care-recipients-in-ontario
#15
Dawn M Guthrie, Jacob G S Davidson, Nicole Williams, Jennifer Campos, Kathleen Hunter, Paul Mick, Joseph B Orange, M Kathleen Pichora-Fuller, Natalie A Phillips, Marie Y Savundranayagam, Walter Wittich
OBJECTIVES: The objective of the current study was to understand the added effects of having a sensory impairment (vision and/or hearing impairment) in combination with cognitive impairment with respect to health-related outcomes among older adults (65+ years old) receiving home care or residing in a long-term care (LTC) facility in Ontario, Canada. METHODS: Cross-sectional analyses were conducted using existing data collected with one of two interRAI assessments, one for home care (n = 291,824) and one for LTC (n = 110,578)...
2018: PloS One
https://www.readbyqxmd.com/read/29447177/physician-prescribing-of-opioid-agonist-treatments-in-provincial-correctional-facilities-in-ontario-canada-a-survey
#16
Fiona G Kouyoumdjian, Alexandra Patel, Matthew J To, Lori Kiefer, Leonora Regenstreif
BACKGROUND: Substance use and substance use disorders are common in people who experience detention or incarceration in Canada, and opioid agonist treatment (OAT) may reduce the harms associated with substance use disorders. We aimed to define current physician practice in provincial correctional facilities in Ontario with respect to prescribing OAT and to identify potential barriers and facilitators to prescribing OAT. METHODS: We invited all physicians practicing in the 26 provincial correctional facilities for adults in Ontario to participate in an online survey...
2018: PloS One
https://www.readbyqxmd.com/read/29445521/a-method-for-co-creation-of-an-evidence-based-patient-workbook-to-address-alcohol-use-when-quitting-smoking-in-primary-care-a-case-study
#17
Nadia Minian, Aliya Noormohamed, Laurie Zawertailo, Dolly Baliunas, Norman Giesbrecht, Bernard Le Foll, Jürgen Rehm, Andriy Samokhvalov, Peter L Selby
Plain English summary: The purpose of this paper is to describe a patient engagement event designed to create an educational workbook with smokers who drink alcohol at harmful levels. The goal was to create a workbook that combined scientific evidence with patients' values, preferences, and needs. Fourteen adult smokers who drink alcohol were invited to the Centre for Addiction and Mental Health (CAMH) to take part in a four-hour event to help design the workbook with the CAMH research team...
2018: Research involvement and engagement
https://www.readbyqxmd.com/read/29444969/atrial-fibrillation-detected-after-stroke-is-related-to-a-low-risk-of-ischemic-stroke-recurrence
#18
Luciano A Sposato, Joshua O Cerasuolo, Lauren E Cipriano, Jiming Fang, Sebastian Fridman, Maryse Paquet, Gustavo Saposnik
OBJECTIVE: To compare the risk of 1-year ischemic stroke recurrence between atrial fibrillation (AF) diagnosed after stroke (AFDAS) and sinus rhythm (SR) and investigate whether underlying heart disease is as frequent in AFDAS as it is in AF known before stroke (KAF). METHODS: In this retrospective cohort study, we included all ischemic stroke patients admitted to institutions participating in the Ontario Stroke Registry from July 1, 2003, to March 31, 2013. Based on heart rhythm assessed during admission, we classified patients as AFDAS, KAF, or SR...
February 14, 2018: Neurology
https://www.readbyqxmd.com/read/29444925/increasing-incidence-and-prevalence-of-world-health-organization-groups-1-to-4-pulmonary-hypertension-a-population-based-cohort-study-in-ontario-canada
#19
D Thiwanka Wijeratne, Katherine Lajkosz, Susan B Brogly, M Diane Lougheed, Li Jiang, Ahmad Housin, David Barber, Ana Johnson, Katharine M Doliszny, Stephen L Archer
BACKGROUND: The World Health Organization recognizes 5 groups of pulmonary hypertension (PH), categorized by pathogenesis or comorbidity: 1-pulmonary arterial hypertension 2-left-heart disease, 3-lung disease and hypoxia 4-chronic thromboembolic disease, and 5-miscellaneous. The epidemiology of PH, apart from group 1, is largely unknown. METHODS AND RESULTS: We describe incidence, prevalence, comorbidities, mortality and prescribing patterns for groups 1 to 4 PH from 1993 to 2012...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29444228/towards-optimal-electronic-medical-record-use-perspectives-of-advanced-users
#20
Amanda L Terry, Bridget L Ryan, Scott McKay, Michael Oates, Jill Strong, Kate McRobert, Amardeep Thind
Background: While primary health care electronic medical record (EMR) adoption has increased in Canada, the use of advanced EMR features is limited. Realizing the potential benefits of primary health care EMR use is dependent not only on EMR acquisition, but also on its comprehensive use and integration into practice; yet, little is known about the advanced use of EMRs in primary health care. Objective: To explore the views of advanced primary health care EMR users practising in a team-based environment...
February 10, 2018: Family Practice
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