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https://www.readbyqxmd.com/read/28445775/changes-in-social-isolation-and-loneliness-following-total-hip-and-knee-arthroplasty-longitudinal-analysis-of-the-english-longitudinal-study-of-ageing-elsa-cohort
#1
Toby O Smith, Jack R Dainty, Alex Macgregor
OBJECTIVE: To determine the prevalence and change in social isolation and loneliness in people before and after THA and TKA in England. DESIGN: The English Longitudinal Study of Ageing dataset, a prospective study of community-dwelling older adults, was used to identify people who had undergone primary THA or TKA because of osteoarthritis. Social isolation was assessed using the ELSA Social Isolation Index. Loneliness was evaluated using the Revised University of California, Los Angeles (UCLA) Loneliness Scale...
April 23, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28445590/long-term-radiographic-findings-of-breast-brachytherapy-implications-of-surgical-volume
#2
Audrey S Wallace, Vladislav Tchatalbachev, Jay Nelson, Zhenyu Wang, Paul Dale, Gregory B Biedermann
PURPOSE: Little is known about long-term radiographic findings after treatment with accelerated partial breast irradiation (APBI). METHODS: Univariate and multivariate analysis of factors leading to formation and resolution of seroma were performed in patients treated with lumpectomy and APBI. RESULTS: Post-treatment images of 129 patients were reviewed by one radiologist. Median surgical excision volume was 108.9 cc (range 20.5-681.9). Primary mode of imaging was mammogram...
April 26, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28445566/variation-in-outcomes-at-bariatric-surgery-centers-of-excellence
#3
Andrew M Ibrahim, Amir A Ghaferi, Jyothi R Thumma, Justin B Dimick
Importance: In the United States, reports about perioperative complications associated with bariatric surgery led to the establishment of accreditation criteria for bariatric centers of excellence and many bariatric centers obtaining accreditation. Currently, most bariatric procedures occur at these centers, but to what extent they uniformly provide high-quality care remains unknown. Objective: To describe the variation in surgical outcomes across bariatric centers of excellence and the geographic availability of high-quality centers...
April 26, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28445503/therapeutic-efficacy-of-artemether-lumefantrine-against-uncomplicated-plasmodium-falciparum-malaria-in-a-high-transmission-area-in-northwest-ethiopia
#4
Michael Teklemariam, Ashenafi Assefa, Moges Kassa, Hussien Mohammed, Hassen Mamo
Malaria, particularly due to Plasmodium falciparum, remains a major public health threat in Ethiopia. Artemether-lumefantine (AL) has been the first-line antimalarial drug against uncomplicated P. falciparum malaria in the country since 2004. Regular monitoring of antimalarial drugs is recommended by the World Health Organization (WHO) to help early detection of drug resistant strains of the parasite and contain their rapid spread. The objective of this study was to assess the therapeutic efficacy of AL in a high-transmission setting in Ethiopia...
2017: PloS One
https://www.readbyqxmd.com/read/28445369/a-systematic-review-of-different-implants-and-approaches-for-proximal-interphalangeal-joint-arthroplasty
#5
Michiro Yamamoto, Sunitha Malay, Yuki Fujihara, Lin Zhong, Kevin C Chung
BACKGROUND: Outcomes after implant arthroplasty for primary degenerative and posttraumatic osteoarthritis of the proximal interphalangeal joint were different according to the implant design and surgical approach. The purpose of this systematic review was to evaluate outcomes of various types of implant arthroplasty for proximal interphalangeal joint osteoarthritis, with an emphasis on different surgical approaches. METHODS: The authors searched all available literature in the PubMed and EMBASE databases for articles reporting on outcomes of implant arthroplasty for proximal interphalangeal joint osteoarthritis...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445357/the-challenges-of-augmentation-mastopexy-in-the-massive-weight-loss-patient-technical-considerations
#6
Demetrius M Coombs, Udayan Srivastava, Dalit Amar, J Peter Rubin, Jeffrey A Gusenoff
BACKGROUND: Augmentation mastopexy in the massive weight loss population is challenging because of poor skin elasticity and lack of inframammary support. Despite several large studies of augmentation mastopexy in the literature, few data exist regarding this unique patient population. The authors examine early postoperative ptosis, implant malposition, and strategies to optimize outcomes. METHODS: A retrospective review of massive weight loss patients who underwent augmentation mastopexy from 2003 to 2011 was performed to record age, body mass index, implant characteristics, postoperative ptosis, and implant malposition...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445350/shaped-versus-round-implants-in-breast-reconstruction-a-multi-institutional-comparison-of-surgical-and-patient-reported-outcomes
#7
Nima Khavanin, Mark W Clemens, Andrea L Pusic, Neil A Fine, Jennifer B Hamill, H Myra Kim, Ji Qi, Edwin G Wilkins, John Y S Kim
BACKGROUND: Since the 2012 approval of shaped implants, their use in breast reconstruction has increased in the United States. However, large-scale comparisons of complications and patient-reported outcomes are lacking. The authors endeavored to compare surgical and patient-reported outcomes across implant types. METHODS: The Mastectomy Reconstruction Outcomes Consortium database was queried for expander/implant reconstructions with at least 1-year postexchange follow-up (mean, 18...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445314/bc-prom-validation-of-a-patient-reported-outcomes-measure-for-patients-with-breast-cancer
#8
Xiaojuan Hu, Chunsen Zhang, Yanbo Zhang
Key issues of treatment for patients with breast cancer such as patient satisfaction with treatments, compliance, and some side effects are essential for evaluating quality of life by patient-reported outcomes in clinical trials. The study aimed to develop and evaluate a specific patient-reported measure which included physical, psychological, social, and therapeutic domain for assessing the survival of patients with breast cancer.The pool of items was drafted after a theoretical revision and cognitive interviews with women with breast cancer...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445310/diagnostic-accuracy-of-serum-alanine-aminotransferase-as-biomarker-for-nonalcoholic-fatty-liver-disease-and-insulin-resistance-in-healthy-subjects-using-3t-mr-spectroscopy
#9
Jose Luis Martin-Rodriguez, Jorge Gonzalez-Cantero, Alvaro Gonzalez-Cantero, Juan Pedro Arrebola, Jorge Luis Gonzalez-Calvin
Recognition of the close relationship of nonalcoholic fatty liver disease (NAFLD) with diabetes mellitus 2, obesity, metabolic syndrome, and cardiovascular disease has stimulated growing interest in NAFLD as a public health problem. Serum alanine aminotransferase (ALT) has been proposed as a marker of NAFLD, but levels are within the range currently considered "normal" in a large proportion of NAFLD subjects.The aim of the study was to determine the diagnostic accuracy of serum ALT for identifying individuals with NAFLD, using 3-Tesla (T) magnetic resonance spectroscopy (H-MRS)...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445308/clinical-value-of-radionuclide-shuntography-by-qualitative-methods-in-hydrocephalic-adult-patients-with-suspected-ventriculoperitoneal-shunt-malfunction
#10
Szu-Ying Tsai, Shan-Ying Wang, Yu-Chien Shiau, Lin-Hsue Yang, Yen-Wen Wu
To determine the clinical value of radionuclide shuntography in the evaluation of adult hydrocephalic patients with suspected ventriculoperitoneal (V-P) shunt malfunction. All adult patients who underwent Tc-99m diethylenetriamine pentaacetic acid shuntographic scans at Far Eastern Memorial Hospital between August 2005 and December 2015 were included. Shuntographic results were visually evaluated in a simple qualitative manner: prompt flow that reached the peritoneum on 30-minute early images and diffuse peritoneal tracer distribution on 2-hour delayed images were interpreted as nonobstructive shunt flow...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445259/the-role-of-stat3-and-ahr-in-the-differentiation-of-cd4-t-cells-into-th17-and-treg-cells
#11
Xingxing Liu, Hui Hu, Heng Fan, Dongmei Zuo, Zhexing Shou, Yi Liao, Zhen Nan, Qing Tang
BACKGROUND: This study aimed to investigate the role of aryl hydrocarbon receptor (AhR) and STAT3 gene during the differentiation of cluster of differentiation (CD)4 T cells into T helper (Th)17 and T regulatory (Treg) cells. METHODS: First, CD4 T cells were isolated from the spleen of BALB/c mice. Then, stable CD4 T cells expressing STAT3 shRNA were constructed. CD4 T cells were assigned to one of the following treatments: Th17 group: antibodies against CD3 and CD28, 2...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445100/remap-a-framework-for-goals-of-care-conversations
#12
Julie W Childers, Anthony L Back, James A Tulsky, Robert M Arnold
Conversations regarding goals of care with patients who have advanced cancer still occur too late, and oncologists say they lack the training to have these conversations effectively. Experts recommend a number of strategies when having these discussions, including discussing prognosis, responding to patient emotion, exploring values, and often making a recommendation for medical treatments that fit those values. To help learners, from residents to attending oncologists, learn these complex conversational skills, we have developed a framework with a mnemonic, REMAP: Reframe, Expect emotion, Map out patient goals, Align with goals, and Propose a plan...
April 26, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28444584/corr-insights-%C3%A2-single-stage-acetabular-revision-during-two-stage-tha-revision-for-infection-is-effective-in-selected-patients
#13
Dror Lakstein
No abstract text is available yet for this article.
April 25, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28444541/reverse-shoulder-arthroplasty-for-massive-irreparable-rotator-cuff-tears-and-cuff-tear-arthropathy-a-systematic-review
#14
REVIEW
S Petrillo, U G Longo, R Papalia, V Denaro
PURPOSE: To report the outcomes and complications of reverse shoulder arthroplasty (RSA) in massive irreparable rotator cuff tears (MIRCT) and cuff tear arthropathy (CTA). METHODS: A systematic review of the literature contained in Medline, Cochrane, EMBASE, Google Scholar and Ovid databases was conducted on May 1, 2016, according to PRISMA guidelines. The key words "reverse total shoulder arthroplasty" or "reverse total shoulder prostheses" with "rotator cuff tears"; "failed rotator cuff surgery"; "massive rotator cuff tears"; "irreparable rotator cuff tears"; "cuff tear arthropathy"; "outcomes"; "complications" were matched...
April 25, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28444407/-aseptic-loosening-of-total-ankle-replacement-and-conversion-to-ankle-arthrodesis
#15
M D Wimmer, M Hettchen, M M Ploeger, B Hintermann, D C Wirtz, A Barg
OBJECTIVE: To remove loosened prosthesis components, to perform augmentation, to address osseous defects, to perform neutrally aligned ankle arthrodesis, and to achieve postoperative pain relief. INDICATIONS: Symptomatic, aseptic loosening of total ankle replacement (TAR) with/without substantial bone defect of the tibial and/or talar bone stock. CONTRAINDICATIONS: General surgical or anesthesiological risks, periprosthetic infection, local or systemic infection, nonmanageable soft tissue problems...
April 25, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28444337/utility-of-a-repeat-renal-biopsy-in-lupus-nephritis-a-single-centre-experience
#16
Angela Pakozdi, Debasish Pyne, Michael Sheaff, Ravindra Rajakariar
Background.: The role of repeat renal biopsy in lupus nephritis (LN) to guide treatment or predict prognosis has been controversial. We assessed glomerular and tubulointerstitial histological characteristics of serial renal biopsies, correlations with clinical variables and the impact on subsequent management. Methods.: Out of a large single-centre cohort of 270 biopsy- proven LN patients, 66 (24%) had serial biopsies. LN classes based on glomerular pathology were defined according to the International Society of Nephrology/Renal Pathology Society 2003 classification, while tubulointerstitial pathologies were evaluated using the revised Austin's semi-quantitative scoring system...
April 22, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28444155/hospitalization-rates-among-people-with-hiv-aids-in-new-york-city-2013
#17
Rachael Lazar, Laura Kersanske, Qiang Xia, Demetre Daskalakis, Sarah L Braunstein
Background: Hospitalizations are an important indicator of health care quality and access for people with HIV/AIDS. This study assesses hospitalization rates among people with HIV/AIDS in New York City. Methods: We performed a deterministic match between people in the New York City HIV surveillance registry alive as of 1/1/2013 and diagnosed with HIV as of 12/31/2013 and patient-level inpatient hospitalization records during 2013. Event-level data were analyzed to determine characteristics of and reasons for hospitalizations...
April 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444119/spatial-variability-in-adhd-related-behaviors-among-children-born-to-mothers-residing-near-the-new-bedford-harbor-superfund-site
#18
Verónica M Vieira, M Patricia Fabian, Thomas F Webster, Jonathan I Levy, Susan A Korrick
Attention-deficit/hyperactivity disorder (ADHD) has an uncertain etiology, with potential contributions from different risk factors such as prenatal environmental exposure to organochlorines and metals, social risk factors, and genetics. The degree to which geographic variability in ADHD is independent of, or explained by, risk factors may provide etiological insight. We investigated determinants of geographic variation in ADHD-related behaviors among children living near the polychlorinated biphenyl-contaminated New Bedford Harbor (NBH) Superfund site in Massachusetts...
April 24, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28444032/thoughts-on-the-development-of-active-regional-public-health-systems
#19
Ademar Arthur Chioro Dos Reis, Ana Paula Menezes Sóter, Lumena Almeida Castro Furtado, Silvana Souza da Silva Pereira
Decentralization and regionalization are strategic themes for reforms in the health system. This paper analyzes the complex process of health regionalization being developed in Brazil. This paper identifies that the normative framework from the Brazilian National Health System, SUS has made advances with respect to its institutionalization and overcoming the initial centrality involved in municipalization. This has strengthened the development of regionalization and the intergovernmental agreement on health but the evidence points to the need to promote a revision...
April 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28443894/taste-and-smell-in-aquatic-and-terrestrial-environments
#20
REVIEW
E Mollo, M J Garson, G Polese, P Amodeo, M T Ghiselin
Covering: up to 2017The review summarizes results up to 2017 on chemosensory cues occurring in both aquatic and terrestrial environments. The chemicals are grouped by their physicochemical properties to compare their potential mobility in the different media. In contrast to what is widely asserted in the literature, the report emphasizes that living organisms encounter and sense molecules of various degrees of solubility and volatility both on land and in aquatic environments. The picture that emerges from the review suggests a substantial revision of the traditional definitions of the chemical senses based on their spatial range, which is currently orienting the literature on chemosensory signaling, in favor of a new vision based on the natural products that are the actual mediators of the chemosensory perceptions...
April 26, 2017: Natural Product Reports
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