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Fibromuscular dysplasia

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https://www.readbyqxmd.com/read/29904460/regarding-the-case-of-postpartum-sudden-cardiac-death-after-spontaneous-coronary-artery-dissection-in-a-patient-with-fibromuscular-dysplasia
#1
Brandon W Calenda, Jeffrey W Olin
No abstract text is available yet for this article.
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29904459/unusual-presentation-of-spontaneous-coronary-artery-dissection-in-an-older-male
#2
Rajveer Joea, Sarah J Strube, Todd K Zynda
Spontaneous coronary artery dissection (SCAD) is a variant of acute coronary syndrome (ACS) that is poorly understood. SCAD has been linked to fibromuscular dysplasia (FMD), connective tissue disease (CTD), pregnancy and hormonal imbalance, systemic inflammatory conditions (e.g. IBD, vasculitis), and coronary artery vasospasm rather than traditional cardiac risk factors. Symptomology generally accompanying SCAD is indistinguishable from ACS making the timely recognition and diagnosis vital for prompt treatment...
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29889158/differences-in-renal-hemodynamics-and-renin-secretion-between-patients-with-unifocal-and-multifocal-fibromuscular-dysplasia
#3
Daan J L van Twist, Pieter W M de Heer, Alfons J H M Houben, Michiel W de Haan, Peter W de Leeuw, Abraham A Kroon
OBJECTIVE: Fibromuscular dysplasia (FMD) can be classified in a multifocal and a unifocal subtype. As unifocal FMD generally leads to more severe hypertension at younger age, we hypothesized that renal hemodynamics are more disturbed in unifocal renal artery FMD as compared with multifocal FMD, leading to increased renin secretion. METHODS: We measured renal blood flow (Xenon washout method), renin secretion, and glomerular filtration rate per kidney in 101 patients with FMD (26 unifocal and 75 multifocal), all off medication and prior to balloon angioplasty...
June 7, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29883369/genomics-of-fibromuscular-dysplasia
#4
REVIEW
Silvia Di Monaco, Adrien Georges, Jean-Philippe Lengelé, Miikka Vikkula, Alexandre Persu
Fibromuscular Dysplasia (FMD) is &ldquo;an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries&rdquo; (Persu, et al; 2014). FMD can lead to hypertension, arterial dissections, subarachnoid haemorrhage, stroke or mesenteric ischemia. The pathophysiology of the disease remains elusive. While familial cases are rare (<5%) in contemporary FMD registries, there is evidence in favour of the existence of multiple genetic factors involved in this vascular disease...
May 21, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29869115/imaging-studies-in-pediatric-fibromuscular-dysplasia-fmd-a-single-center-experience
#5
Robert Louis, Daniella Levy-Erez, Anne Marie Cahill, Kevin E Meyers
BACKGROUND: Fibromuscular dysplasia (FMD) is a non-inflammatory vascular disease that in children unlike in adults shows no sex predilection. FMD is often underdiagnosed, and its pathophysiology is unclear. Delayed diagnosis may lead to refractory hypertension and decreases the chance of successful treatment. Doppler ultrasound (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and catheter-based angiography (angiography) are currently used to help make a clinicoradiological diagnosis of FMD...
June 4, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29861130/renovascular-hypertension-in-small-children-is-it-takayasu-arteritis-or-fibromuscular-dysplasia
#6
EDITORIAL
Kjell Tullus, Derek J Roebuck
No abstract text is available yet for this article.
May 9, 2018: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29803123/comparing-coronary-artery-fibromuscular-dysplasia-with-coronary-atherosclerosis-from-clinical-to-histopathological-characteristics
#7
Xiumeng Hua, Xiao Chen, Kai Chen, Songqing Lai, Ran Gao, Yiqing Hu, Jiangping Song
No abstract text is available yet for this article.
April 30, 2018: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/29796733/a-refractory-hypertensive-patient-with-fibromuscular-dysplasia-and-multicystic-dysplastic-kidney
#8
Shin Takahashi, Yurie Takizawa, Satoshi Nakano, Kotaro Oyama
The case of a 16-year-old male patient with left renal artery stenosis due to fibromuscular dysplasia (FMD) and an atrophic kidney due to a right multicystic dysplastic kidney (MCDK) who presented with refractory hypertension is reported. On continuous Doppler imaging, the peak systolic velocity (PSV) at the stenotic site of the left renal artery was 404 cm/s. The FMD formed a "string-of-beads" appearance on computed tomographic angiography (CTA) and renal artery angiography. Percutaneous transluminal renal angioplasty (PTRA) with a balloon catheter was performed, after which the left renal artery returned to near normal, and his blood pressure decreased to within the normal range...
May 23, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29787367/case-ex-vivo-aneurysm-resection-autotransplantation-and-aorto-renal-bypass-in-a-solitary-kidney-with-fibromuscular-dysplasia
#9
Gautamn Sarwal, Hilary L Brotherhood, Edmund C P Chedgy, David C Taylor, Alex G Kavanagh
No abstract text is available yet for this article.
May 14, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29709956/fibromuscular-dysplasia-another-paradigm-shift-in-renovascular-hypertension
#10
Katsutoshi Takahashi, Toshiyuki Unno
No abstract text is available yet for this article.
April 27, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29709948/sequential-symptomatic-arterial-dissections-in-multiple-vascular-beds-in-a-patient-with-fibromuscular-dysplasia
#11
Yuki Sakamoto, Ryo Hiruta, Ayako Iijima, Yuya Sakuma, Yutaka Konno
A 60-year-old man was admitted to our hospital because of abdominal pain and disturbed consciousness. Head magnetic resonance imaging showed right vertebral artery dissection and abdominal enhanced computed tomography showed dissection of the superior mesenteric artery. The patient was diagnosed as having fibromuscular dysplasia (FMD) based on conventional angiography. Although multiple vascular bed involvement is observed in approximately 40% of FMD patients, reports of sequential symptomatic dissections in various vascular beds are rare...
April 27, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29709926/a-unique-case-of-renovascular-hypertension-due-to-fibromuscular-dysplasia-in-an-extra-renal-artery
#12
Ikki Sakuma, Jun Saito, Yoko Matsuzawa, Masao Omura, Seiji Matsui, Tetsuo Nishikawa
A 33-year-old man was admitted to our hospital to undergo an evaluation to determine the cause of secondary hypertension. Computerized tomography angiography (CTA) showed bilateral multiple renal arteries with significant stenosis of the right extra-renal artery due to fibromuscular dysplasia and segmental impairment of renal perfusion. Although the plasma aldosterone concentration and plasma renin activity were within the normal ranges, percutaneous balloon dilatation of the stenotic lesion resolved his hypertension, leading to a diagnosis of renovascular hypertension caused by segmental renal ischemia due to extra-renal artery stenosis...
April 27, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29680214/histopathology-of-coronary-fibromuscular-dysplasia-causing-spontaneous-coronary-artery-dissection
#13
Nathaniel Moulson, James Kelly, M Bilal Iqbal, Jacqueline Saw
No abstract text is available yet for this article.
May 14, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29679353/low-frequency-of-cervicocranial-artery-involvement-in-japanese-with-renal-artery-fibromuscular-dysplasia-compared-with-that-of-caucasians
#14
Eikan Mishima, Shu Umezawa, Takehiro Suzuki, Miki Fujimura, Michiaki Abe, Junichiro Hashimoto, Takaaki Abe, Sadayoshi Ito
BACKGROUND: Fibromuscular dysplasia (FMD), which usually affects the renal artery, also affects the carotid, vertebral, and intracranial arteries. Previous studies have shown a high prevalence of concomitant renal artery and cervicocranial lesions in FMD patients. However, the analyzed subjects were mostly Caucasians in Western countries. METHOD: We performed a retrospective analysis to examine the prevalence of cervicocranial vascular lesions in Japanese FMD patients with renal artery involvement at a single institution...
April 20, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29650765/prospective-cardiovascular-genetics-evaluation-in-spontaneous-coronary-artery-dissection
#15
M Ihsan Kaadan, Carolyn MacDonald, Francesca Ponzini, Jessica Duran, Kelsey Newell, Linda Pitler, Angela Lin, Ido Weinberg, Malissa J Wood, Mark E Lindsay
BACKGROUND: Previous studies describing genetics evaluation in spontaneous coronary artery dissection (SCAD) have been retrospective in nature or presented as single case reports. As part of a dedicated clinical program, we evaluated patients in cardiovascular genetics clinic to determine the role of genetically triggered vascular disease and genetic testing in SCAD. METHODS AND RESULTS: Patient data were entered prospectively into the Massachusetts General Hospital SCAD registry database from July 2013 to September 2017...
April 2018: Circulation. Genomic and precision medicine
https://www.readbyqxmd.com/read/29628950/safety-assessment-of-endovascular-treatment-of-cerebral-aneurysms-in-patients-with-fibromuscular-dysplasia
#16
Matthew T Bender, Christopher Hurtado, Bowen Jiang, Jessica K Campos, Judy Huang, Rafael J Tamargo, Li-Mei Lin, Alexander L Coon, Geoffrey P Colby
Background: The prevalence of cerebral aneurysms is increased in fibromuscular dysplasia (FMD). The presence of FMD may serve as discouragement to elective endovascular aneurysm treatment. Outcomes of endovascular intervention for aneurysms through vessels affected by FMD have not been reported. Methods: A prospectively maintained database of patients undergoing intracranial embolization was reviewed for patients with FMD who underwent endovascular aneurysm treatment...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29568781/renal-artery-rupture-in-association-with-fibromuscular-dysplasia
#17
Tamer Akel, Suzanne Elsayegh
Fibromuscular dysplasia is a noninflammatory arteriopathy of unknown etiology that affects medium-sized arteries. Although patients affected with it are often asymptomatic, some might have recurrent catastrophic events that depend mainly on the arterial bed involved. The most worrisome vascular complications of the disease are aneurysmal rupture and arterial dissection. Herein, we report a case of a 49-year-old woman who presented with sudden-onset abdominal pain without any inciting factors. She was found to have active blood extravasation from a capsular branch of the renal artery that happened spontaneously...
January 2018: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29560003/a-rare-case-of-carotid-web-presenting-with-ischemic-stroke-in-a-young-woman-and-a-brief-review-of-the-literature
#18
Kyaw Kyaw, Htun Latt, Sammy San Myint Aung, Jay Babu, Rajesh Rangaswamy
Carotid web is a radiological description of a shelf-like intraluminal filling defect in the carotid bulb. It is histologically defined as atypical fibromuscular dysplasia (FMD), with abnormal fibrosis and smooth muscle cell hyperplasia in the tunica intima . The spur-like intraluminal protrusion can serve as a nidus for thrombus formation, which could cause systemic embolism and ischemic strokes. We report a case of a 20-year-old female patient presenting with acute ischemic stroke in the ipsilateral middle cerebral artery (MCA) territory...
2018: Case Reports in Medicine
https://www.readbyqxmd.com/read/29535868/factors-associated-with-outcomes-of-percutaneous-transluminal-renal-angioplasty-in-patients-with-renal-artery-stenosis-a-retrospective-analysis-of-50-consecutive-cases
#19
Tetsutaro Matayoshi, Kei Kamide, Ryoichi Tanaka, Tetsuya Fukuda, Takeshi Horio, Yoshio Iwashima, Fumiki Yoshihara, Satoko Nakamura, Hajime Nakahama, Yusuke Ohya, Yuhei Kawano
Background: The results of recent trials have brought some confusion to the treatment strategy for renal artery stenosis (RAS). To evaluate the applicability of percutaneous transluminal renal angioplasty (PTRA) for RAS, we extracted the factors that may affect the effectiveness of PTRA from cases experienced at a hypertension center. Methods and Results: We retrospectively assessed the blood pressure (BP) lowering effects and renoprotective effects in 50 consecutive patients that had hemodynamically significant RAS and had undergone PTRA and stenting during 2001-2005...
2018: International Journal of Hypertension
https://www.readbyqxmd.com/read/29534984/fibromuscular-dysplasia-contemporary-concepts-and-future-directions
#20
REVIEW
Nupoor Narula, Daniella Kadian-Dodov, Jeffrey W Olin
Fibromuscular dyplasia (FMD) is an under-recognized non-atherosclerotic, non-inflammatory arteriopathy that occurs most commonly in middle-aged women, but may affect individuals of all age groups. FMD may result in stenosis, aneurysm, dissection, occlusion, or arterial tortuosity. Recently published data demonstrated a genetic association of FMD with a variant in the phosphatase and actin regulator 1 gene (PHACTR1), substantiating that the pathogenesis of this condition has genetic contribution. The renal and extracranial carotid and vertebral arteries are most often involved, although any arterial bed may be affected...
March 10, 2018: Progress in Cardiovascular Diseases
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