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Fibromuscular dysplasia

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https://www.readbyqxmd.com/read/27889328/multiple-spontaneous-coronary-artery-dissections-an-uncommon-cause-of-acute-coronary-syndrome-in-a-syrian-refugee
#1
Tina Zhu, Peggy DeJong, Amer M Johri
Spontaneous coronary artery dissection is an uncommon nonatherosclerotic cause of acute coronary syndrome. It usually occurs in young women and is often associated with fibromuscular dysplasia, connective tissue diseases, and pregnancy or postpartum states. We present a case of a Syrian woman with a history of grand multiparity and recent miscarriage who presented with non-ST-elevation myocardial infarction and was found to have multivessel spontaneous coronary artery dissection and severe left ventricular dysfunction...
August 24, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27884363/fibromuscular-dysplasia-presented-with%C3%A2-spontaneous-dissection-of-the-left%C3%A2-main-artery
#2
Mahmoud Abdelghany, Puneet Bansal, Hani Kozman
No abstract text is available yet for this article.
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27872233/effects-of-percutaneous-transluminal-renal-angioplasty-on-office-and-home-blood-pressure-and-home-blood-pressure-variability-in-hypertensive-patients-with-renal-artery-stenosis
#3
Yoshio Iwashima, Tetsuya Fukuda, Hiroshi Kusunoki, Shin-Ichiro Hayashi, Masatsugu Kishida, Fumiki Yoshihara, Satoko Nakamura, Kei Kamide, Takeshi Horio, Yuhei Kawano
This study included 126 hypertensive patients with renal artery stenosis (mean age, 63 years; 22.2% fibromuscular dysplasia [FMD]) and investigated the effects of percutaneous transluminal renal angioplasty on office and home blood pressure (BP), and BP variability estimates derived from home BP, both at baseline and up to 12 months after angioplasty. Home BP was measured for 7 consecutive days, and the threshold defining uncontrolled home BP was ≥135/85 mm Hg. In both the FMD and atherosclerotic stenosis (ARAS) groups, office and home BP decreased significantly after angioplasty (all P<0...
November 21, 2016: Hypertension
https://www.readbyqxmd.com/read/27861117/fibromuscular-dysplasia-advances-in-understanding-and-management
#4
REVIEW
Ellen K Brinza, Heather L Gornik
Several key findings in recent years have reshaped our understanding of fibromuscular dysplasia (FMD), an uncommon nonatherosclerotic disease of medium-sized arteries that affects mainly women. While the true prevalence of this disease remains unknown, studies suggest that more people may be affected than previously reported. Better understanding of the clinical manifestations and natural history of FMD and advances in diagnostic imaging have altered the clinical approach to managing patients with this uncommon vascular disease...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27854110/association-between-carotid-artery-tortuosity-and-carotid-dissection-a-case-control-study
#5
Sarasa T Kim, Waleed Brinjikji, Vance T Lehman, Carrie M Carr, Patrick H Luetmer, Charlotte H Rydberg
BACKGROUND: Carotid artery dissections have long been associated with compromise of the structural integrity of the arterial wall from heritable connective-tissue disorders, hypertension, and trauma. However, an association between spontaneous internal carotid artery dissection and tortuous or redundant carotid anatomy has not been fully explored. METHODS: Patients with CTA confirmed spontaneous cervical internal carotid artery dissections were compared to a group of age and sex matched controls who also received CTA of the neck...
November 17, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27827286/-hypertension-due-to-fibromuscular-dysplasia-look-for-additional-disease-sites
#6
M L Maas, J M Kroese, S J H Bredie, C T Postma, F E de Leeuw, L J Schultze Kool, N P Riksen
Fibromuscular dysplasia (FMD) is a non-inflammatory, non-atherosclerotic vasculopathy that can lead to arterial stenosis, occlusion, aneurysms, and dissection. FMD of the renal arteries can lead to renovascular hypertension. Percutaneous angioplasty of the renal arteries (PTRA) can lead to normalization of blood pressure in 45% of patients with renal artery stenosis caused by FMD, particularly in younger patients and patients with a short history of hypertension. A considerable number of the patients with renovascular FMD also have cervical FMD, which can lead to ischaemic or haemorrhagic stroke...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27801305/spontaneous-coronary-artery-dissection-after-minimally-invasive-mitral-valve-repair
#7
Mirko Muretti, Mario Manca, Francesco Massi, Michele Portoghese
Spontaneous coronary artery dissection is a rare condition usually encountered in young women without risk factors for atherosclerotic disease but with tortuous coronary artery or contemporary presence of fibromuscular dysplasia. Sometimes spontaneous coronary dissection occurs in patients with atherosclerotic disease, although without significant epicardial coronary artery stenosis. We report a case of a patient who underwent minimally invasive mitral valve repair, whose initially uneventful postoperative course was complicated by spontaneous coronary artery dissection of the left main causing a life threatening condition...
October 31, 2016: Heart Surgery Forum
https://www.readbyqxmd.com/read/27792790/phactr1-is-a-genetic-susceptibility-locus-for-fibromuscular-dysplasia-supporting-its-complex-genetic-pattern-of-inheritance
#8
Soto Romuald Kiando, Nathan R Tucker, Luis-Jaime Castro-Vega, Alexander Katz, Valentina D'Escamard, Cyrielle Tréard, Daniel Fraher, Juliette Albuisson, Daniella Kadian-Dodov, Zi Ye, Erin Austin, Min-Lee Yang, Kristina Hunker, Cristina Barlassina, Daniele Cusi, Pilar Galan, Jean-Philippe Empana, Xavier Jouven, Anne-Paule Gimenez-Roqueplo, Patrick Bruneval, Esther Soo Hyun Kim, Jeffrey W Olin, Heather L Gornik, Michel Azizi, Pierre-François Plouin, Patrick T Ellinor, Iftikhar J Kullo, David J Milan, Santhi K Ganesh, Pierre Boutouyrie, Jason C Kovacic, Xavier Jeunemaitre, Nabila Bouatia-Naji
Fibromuscular dysplasia (FMD) is a nonatherosclerotic vascular disease leading to stenosis, dissection and aneurysm affecting mainly the renal and cerebrovascular arteries. FMD is often an underdiagnosed cause of hypertension and stroke, has higher prevalence in females (~80%) but its pathophysiology is unclear. We analyzed ~26K common variants (MAF>0.05) generated by exome-chip arrays in 249 FMD patients and 689 controls. We replicated 13 loci (P<10-4) in 402 cases and 2,537 controls and confirmed an association between FMD and a variant in the phosphatase and actin regulator 1 gene (PHACTR1)...
October 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27790125/a-case-of-turner-syndrome-with-multiple-embolic-infarcts
#9
Cindy W Yoon, Eungseok Lee, Byung-Nam Yoon, Hee-Kwon Park, Joung-Ho Rha
Only a few cases of Turner syndrome (TS) with ischemic stroke have been reported. Various arteriopathies of the cerebral arteries, including fibromuscular dysplasia, congenital hypoplasia, moyamoya syndrome, and premature atherosclerosis have been assumed to be the cause of ischemic stroke in TS. There has been no case report of a TS patient presenting with an embolic stroke pattern without any cerebral arteriopathy. A 28-year-old woman with TS was referred to our hospital because of abnormal brain magnetic resonance imaging (MRI) findings...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27781048/internal-carotid-artery-s-shaped-curve-as-a-marker-of-fibromuscular-dysplasia-in-dissection-related-acute-ischemic-stroke
#10
Diogo C Haussen, Ashutosh Jadhav, Leticia C Rebello, Samir Belagaje, Aaron Anderson, Tudor Jovin, Amin Aghaebrahim, Deepak Gulati, Bryan Wells, Michael Frankel, Raul G Nogueira
BACKGROUND AND PURPOSE: Craniocervical fibromuscular dysplasia (FMD) is associated with dissections and with S-shaped curves in the internal carotid artery (ICA). We evaluated the occurrence of S-curves in patients presenting with acute strokes due to ICA steno-occlusive dissections. METHODS: This was a retrospective review of the interventional databases of two academic tertiary-care institutions. The presence of ICA S-shaped curves, C-shaped curves, 360-degree loops, as well as classic FMD and atherosclerotic changes at the ICA bulb and curve/loop was determined...
September 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27773191/subarachnoid-haemorrhage-due-to-aneurysmal-rupture-secondary-to-fibromuscular-dysplasia
#11
J M Dyke, D M Moss, V A Fabian
No abstract text is available yet for this article.
February 2016: Pathology
https://www.readbyqxmd.com/read/27758900/diagnosed-and-living-with-fibromuscular-dysplasia-a-qualitative-inquiry
#12
Sherry M Bumpus, Christa Kuck, Steven T Heidt, Minnie Bluhm
Fibromuscular dysplasia (FMD) is a vascular disorder about which little has been known until recently. Patients with FMD may suffer from hypertension, aneurysms, or strokes, as well as symptoms associated with local artery damage. As a result of advances in vascular medicine and growing outcomes registries, we now have a better understanding of the FMD disease process and epidemiology. Nevertheless, the consequences of FMD on patients' day-to-day experiences and mental health status are not well understood...
December 2016: Vascular Medicine
https://www.readbyqxmd.com/read/27753918/os-04-02-high-prevalence-of-multisite-fibromuscular-dysplasia-the-arcadia-registry
#13
Pierre-Francois Plouin
OBJECTIVE: ARCADIA (Assessment of Renal and Cervical Artery DysplasIA) is a registry designed to assess in adults with fibromuscular dysplasia (FMD) the distribution of arterial lesions and the frequency of FMD affecting at least two vascular beds (multisite FMD). DESIGN AND METHOD: Patients were eligible if they had non-atherosclerotic, non-inflammatory and non-syndromic stenosing lesions affecting renal (RA) and/or cervico-encephalic (CEA) arteries and gave informed consent to undergo skull to pelvis angiographic imaging using CT-, MR-, or digital subtraction-angiography...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27681247/restenosis-of-renal-artery-fibromuscular-dysplasia-after-percutaneous-angioplasty
#14
Masayuki Tanemoto, Yukio Okazaki
No abstract text is available yet for this article.
November 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27672829/poster-63-vertebral-artery-dissection-resulting-in-cerebellar-cva-after-chiropractic-manipulation-in-a-patient-with-fibromuscular-dysplasia
#15
Ofure Luke, Christine Greiss
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27665162/fibromuscular-dysplasia-looking-beyond-the-string-of-beads
#16
Jeffrey W Olin, Daniella Kadian-Dodov
No abstract text is available yet for this article.
September 16, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27665159/screening-ct-angiography-of-the-aorta-visceral-branch%C3%A2-vessels-and-pelvic-arteries-in-fibromuscular-dysplasia
#17
Michael A Bolen, Ellen Brinza, Rahul D Renapurkar, Esther S H Kim, Heather L Gornik
OBJECTIVES: This study sought to evaluate the diagnostic yield of a dedicated computed tomography angiography (CTA) protocol of the chest, abdomen, and pelvis in patients with fibromuscular dysplasia (FMD). BACKGROUND: FMD is an uncommon vascular disease that may result in stenosis, dissection, or aneurysm of nearly all arterial distributions, typically affecting medium-sized arteries. Findings from the United States Registry for Fibromuscular Dysplasia have suggested the potential need to perform screening imaging of the aorta and medium branch vessels...
September 16, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27650351/clinical-commentary-on-my-life-with-fibromuscular-dysplasia-a-sword-of-damocles
#18
James B Froehlich
No abstract text is available yet for this article.
September 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27643303/os-04-02-high-prevalence-of-multisite-fibromuscular-dysplasia-the-arcadia-registry
#19
Pierre-Francois Plouin
OBJECTIVE: ARCADIA (Assessment of Renal and Cervical Artery DysplasIA) is a registry designed to assess in adults with fibromuscular dysplasia (FMD) the distribution of arterial lesions and the frequency of FMD affecting at least two vascular beds (multisite FMD). DESIGN AND METHOD: Patients were eligible if they had non-atherosclerotic, non-inflammatory and non-syndromic stenosing lesions affecting renal (RA) and/or cervico-encephalic (CEA) arteries and gave informed consent to undergo skull to pelvis angiographic imaging using CT-, MR-, or digital subtraction-angiography...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27641455/management-of-renovascular-hypertension
#20
REVIEW
Aaron Smith, Ron C Gaba, James T Bui, Jeet Minocha
Renal artery stenosis is a potentially reversible cause of hypertension, and transcatheter techniques are essential to its treatment. Angioplasty remains a first-line treatment for stenosis secondary to fibromuscular dysplasia. Renal artery stenting is commonly used in atherosclerotic renal artery stenosis, although recent trials have cast doubts upon its efficacy. Renal denervation is a promising procedure for the treatment of resistant hypertension, and in the future, its indications may expand.
September 2016: Techniques in Vascular and Interventional Radiology
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