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https://www.readbyqxmd.com/read/28829911/chemoradiotherapy-versus-chemoradiotherapy-plus-surgery-for-esophageal-cancer
#1
REVIEW
Balamurugan A Vellayappan, Yu Yang Soon, Geoffrey Y Ku, Cheng Nang Leong, Jiade J Lu, Jeremy Cs Tey
BACKGROUND: Please see Appendix 4 for a glossary of terms.The outcome of patients with esophageal cancer is generally poor. Although multimodal therapy is standard, there is conflicting evidence regarding the addition of esophagectomy to chemoradiotherapy. OBJECTIVES: To compare the effectiveness and safety of chemoradiotherapy plus surgery with that of chemoradiotherapy alone in people with nonmetastatic esophageal carcinoma. SEARCH METHODS: We performed a computerized search for relevant studies, up to Feburary 2017, on the CENTRAL, MEDLINE, and Embase databases using MeSH headings and keywords...
August 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28829829/intermediate-cd14-cd16-monocytes-decline-after-transcatheter-aortic-valve-replacement-and-correlate-with-functional-capacity-and-left-ventricular-systolic-function
#2
Jonas Neuser, Paolo Galuppo, Daniela Fraccarollo, Jens Willig, Tibor Kempf, Dominik Berliner, Johann Bauersachs, Julian Daniel Widder
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is the method of choice for patients with severe aortic valve stenosis, who are ineligible or at high risk for surgery. Though TAVR leads to a significant reduction in mortality, a notable amount of patients are re-hospitalized early after TAVR. Parameters or biomarkers predicting outcome are therefore needed to identify patients who benefit most. Specific monocyte subsets have been associated with cardiovascular diseases and were shown to possess prognostic value...
2017: PloS One
https://www.readbyqxmd.com/read/28828922/preoperative-counseling-in-salvage-total-laryngectomy-content-analysis-of-electronic-medical-records
#3
Nikhila Raol, Elizabeth Lilley, Zara Cooper, Jayme Dowdall, Megan A Morris
Objective To study preoperative counseling in patients undergoing salvage total laryngectomy (STL). Study Design Case series with chart review. Setting Tertiary care academic hospital. Subjects and Methods We reviewed charts of patients ≥18 years undergoing STL between 2005 and 2015. Fifty-eight patients were identified. Notes written within 2 months prior to surgery by head and neck surgical oncologists, radiation oncologists, medical oncologists, speech-language pathologists, social workers, and nurse practitioners were extracted and coded into 4 categories...
August 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28828761/coblation-versus-other-surgical-techniques-for-tonsillectomy
#4
REVIEW
Melissa Pynnonen, Jennifer V Brinkmeier, Marc C Thorne, Lee Yee Chong, Martin J Burton
BACKGROUND: Tonsillectomy is a very common operation and is performed using various surgical methods. Coblation is a popular method because it purportedly causes less pain than other surgical methods. However, the superiority of coblation is unproven. OBJECTIVES: To compare the effects of coblation tonsillectomy for chronic tonsillitis or tonsillar hypertrophy with other surgical techniques, both hot and cold, on intraoperative morbidity, postoperative morbidity and procedural cost...
August 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28828758/open-versus-closed-surgical-exposure-of-canine-teeth-that-are-displaced-in-the-roof-of-the-mouth
#5
REVIEW
Nicola Parkin, Philip E Benson, Bikram Thind, Anwar Shah, Ismail Khalil, Saiba Ghafoor
BACKGROUND: Palatally displaced canines or PDCs are upper permanent canines, commonly known as 'eye' teeth, that are displaced in the roof of the mouth. This can leave unsightly gaps, cause damage to the surrounding roots (which can be so severe that neighbouring teeth are lost or have to be removed) and, occasionally, result in the development of cysts. PDCs are a frequent dental anomaly, present in 2% to 3% of young people.Management of this problem is both time consuming and expensive...
August 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28828746/clinical-safety-of-renaming-encapsulated-follicular-variant-of-papillary-thyroid-carcinoma-is-niftp-truly-benign
#6
David N Parente, Wouter P Kluijfhout, Pim J Bongers, Raoul Verzijl, Karen M Devon, Lorne E Rotstein, David P Goldstein, Sylvia L Asa, Ozgur Mete, Jesse D Pasternak
BACKGROUND: Renaming encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was recently suggested to prevent the overtreatment, cost and stigma associated with this low-risk entity. The purpose of this study is to document the incidence and further assess the clinical outcomes of reclassifying EFVPTC to NIFTP. METHODS: We searched synoptic pathologic reports from a high-volume academic endocrine surgery hospital from 2004 to 2013...
August 21, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28828520/risk-factors-for-metachronous-adenoma-in-the-residual-colon-of-patients-undergoing-curative-surgery-for-colorectal-cancer
#7
Abhilasha Patel, Nigel Williams, Nicholas Parsons, Omar Ali, Francesca Peters, Reesha Ranat, Jasmine Shah, Emma Spector, Ramesh P Arasaradnam
PURPOSE: Adenoma detection in colorectal cancer survivors is poorly characterised with insufficient evidence to inform frequency of surveillance schedule. The aim of this study was to examine adenoma incidence and recurrence in patients who have undergone colorectal cancer resection with curative intent. Survival outcomes were compared to determine if the presence of adenomas could be used to identify patients at higher risk of local recurrence. METHODS: This is a retrospective observational cohort study at a single tertiary institution between 2006 and 2012...
August 21, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28828517/impact-of-abdominal-wall-hernias-and-repair-on-patient-quality-of-life
#8
Deepa V Cherla, Maya L Moses, Cristina P Viso, Julie L Holihan, Juan R Flores-Gonzalez, Lillian S Kao, Tien C Ko, Mike K Liang
BACKGROUND: The modified Activities Assessment Scale (AAS) is a 13-question abdominal wall quality of life (AW-QOL) survey validated in patients undergoing ventral hernia repair (VHR). No studies have assessed AW-QOL among individuals without abdominal wall pathology. The minimal clinically important difference (MCID) of the modified AAS and its implications for the threshold at which VHR should be offered also remain unknown. Our objectives were to (1) establish the AW-QOL of patients with a clinical abdominal wall hernia versus those with no hernia, (2) determine the MCID of the modified AAS, and (3) identify the baseline quality of life (QOL) score at which patients derive little clinical benefit from VHR...
August 21, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28828341/a-review-of-salivary-biomarker-a-tool-for-early-oral-cancer-diagnosis
#9
REVIEW
Shikha Saxena, Bharat Sankhla, Krishna Sireesha Sundaragiri, Akshay Bhargava
The oral squamous cell carcinoma (OSCC) is one of the most common epithelial malignancies with significant morbidity and mortality. Recent observations indicate that the clinical and histological appearance of oral mucosa may not truly depict the damage occurring at the genetic level. This phenotypic and genotypic disparity may account in part for the failure to establish effective screening and surveillance protocols, based on the traditional clinical and microscopic examination. The tumor markers are playing an increasingly important role in cancer detection and management...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28828185/clinical-characteristics-and-outcomes-of-surgical-patients-with-intensive-care-unit-lengths-of-stay-of-90-days-and-greater
#10
Verena Martini, Ann-Kathrin Lederer, Claudia Laessle, Frank Makowiec, Stefan Utzolino, Stefan Fichtner-Feigl, Lampros Kousoulas
BACKGROUND: The aim of this study was to evaluate the influence of prolonged length of stay in an intensive care unit (ICU) on the mortality and morbidity of surgical patients. METHODS: We performed a monocentric and retrospective observational study in the surgical critical care unit of the department of surgery at the Medical Center of the University of Freiburg, Germany. Clinical data was collected from patients assigned to the ICU with a length of stay (LOS) of 90 days and greater...
2017: Critical Care Research and Practice
https://www.readbyqxmd.com/read/28828175/combination-of-dura-turning-over-and-decompressive-craniectomy-a-new-pattern-of-surgery-for-cerebral-infarction-caused-by-craniocerebral-gunshot-injury
#11
Qi-Yong Mei, Yao Li, Chao He, Hong-Wei Shan, Yun-Kun Wang, Yan Dong, Ming-Kun Yu, Li-Jun Hou
BACKGROUND: Craniocerebral gunshot injury refers to a wound caused by a bullet passing through or lodged in brain tissue, resulting in the loss of function of a certain area or other fatal damage to the human brain. Craniocerebral gunshot injury is usually life-threatening and is very common in modern warfare, accounting for the majority of battle casualties. Most of the patients suffer from acute cerebral infarction caused by vascular injury. Lack of early and solid battlefield emergency medical interference adds to the risk of death among the wounded...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28826955/five-year-outcome-of-miniarc-single-incision-sling-used-in-treatment-of-primary-urodynamic-stress-incontinence
#12
Tsia-Shu Lo, Sandy Chua, Chuan Chi Kao, Ma Clarissa Uy-Patrimonio, Rami Ibrahim, Yiap Loong Tan
STUDY OBJECTIVE: To evaluate the effectiveness and safety of the MiniArc single-incision sling in the treatment of urodynamic stress incontinence through 5-years. DESIGN: Retrospective observational study (Canadian Task Force Classification II-2) SETTING: Tertiary referral center PATIENTS: Patients with urodynamic stress incontinence (USI) without needing concurrent procedures who underwent anti-incontinence surgery using the MiniArc SIMS from February 2010-December 2011...
August 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28826863/improvement-of-quality-of-life-in-patients-with-hemifacial-spasm-after-microvascular-decompression-a-prospective-study
#13
Jian Cheng, Ding Lei, Xuhui Hui, Heng Zhang
OBJECTIVE: While not life threatening, hemifacial spasm (HFS) can be disabling and significantly affect quality of life (QOL). The aim of the study was to assess the major factors affecting the QOL and further to investigate the impact of microvascular decompression (MVD) on QOL in patients with HFS. METHODS: Patients with HFS who underwent MVD in our department between 2013 and 2014 were included in this study. The validated, disease-specific questionnaire (HFS-30) was used to evaluate the QOL in patients with HFS before surgery and one year after MVD...
August 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28826805/cognitive-impairment-and-overall-survival-in-frail-surgical-patients
#14
Salima S Makhani, Frances Y Kim, Yuan Liu, Zixun Ye, Jessica L Li, Louis M Revenig, Camille P Vaughan, Theodore M Johnson, Paul S García, Kenneth Ogan, Viraj A Master
BACKGROUND: The definition of frailty, as modeled by the Fried criteria, has been limited primarily to the physical domain. The purpose of this study was to assess the additive value of cognitive function with existing frailty criteria to predict poor postoperative outcomes in a large multidisciplinary cohort of patients undergoing major surgery. STUDY DESIGN: A four-level composite frailty scoring system was created via the combination of the Fried Frailty score and the Emory clock draw test to assess preoperative frailty and cognitive impairment, respectively...
August 4, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28826742/a-comprehensive-review-and-update-on-crohn-s-disease
#15
Mahesh Gajendran, Priyadarshini Loganathan, Anthony P Catinella, Jana G Hashash
The term inflammatory bowel disease (IBD) refers principally to two major categories of chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative colitis (UC). In the United States, it is currently estimated that about 1.5 million people suffer from IBD, causing considerable suffering, mortality and economic loss every year. Yet the cause of IBD is unknown, and until we understand more, prevention or cure will not be possible. There is a lot of variation in the incidence and prevalence of CD based on geographic region, environment, immigrant population, and ethnic groups...
August 18, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28826680/patient-characteristics-associated-with-quality-of-colonoscopy-preparation-a-systematic-review-and-meta-analysis
#16
Kunjal Gandhi, Christina Tofani, Carly Sokach, Devin Patel, David Kastenberg, Constantine Daskalakis
BACKGROUND & AIMS: Some features of patients are associated with inadequate bowel preparation, which reduces the effectiveness of colonoscopy examination. We performed a systematic review and meta-analysis of the association between patients' sociodemographic characteristics, health conditions, and medications with inadequate bowel preparation. METHODS: We searched the PubMed, Scopus, and Cochrane Review databases for randomized controlled trials and cohort (prospective and retrospective), case-control, and cross-sectional studies published through March 2016...
August 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28826283/radiotherapy-and-hyperthermia-with-curative-intent-in-recurrent-high-risk-soft-tissue-sarcomas
#17
Franziska Eckert, Lore Helene Braun, Frank Traub, Hans-Georg Kopp, Bence Sipos, Ulf Lamprecht, Arndt-Christian Müller, Frank Paulsen, Daniel Zips
PURPOSE: Radiotherapy before or after resection is one of the pillars of treatment for localised high risk soft tissue sarcomas. Treatment intensification has been described with concurrent chemotherapy and hyperthermia. The aim of this study is to assess local control after multimodal treatment, focussing on the treatment of local recurrences after surgery only. PATIENTS AND METHODS: Of 42 patients treated in a prospective protocol with radiotherapy and hyperthermia, nine were treated for isolated local recurrences without metastatic spread...
August 21, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28822967/temporal-dynamics-of-cardiac-hypertrophic-growth-in-response-to-pressure-overload
#18
Yuan Wang, Yuannyu Zhang, Guanqiao Ding, Herman May, Jian Xu, Thomas G Gillette, Hang Wang, Zhao V Wang
Hypertension is one of the most important risk factors of heart failure. In response to high blood pressure, the left ventricle manifests hypertrophic growth to ameliorate wall stress, which may progress into decompensation and trigger pathological cardiac remodeling. Despite the clinical importance, the temporal dynamics of pathological cardiac growth remains elusive. Here, we took advantage of the puromycin labeling approach to measure the relative rates of protein synthesis as a way to delineate the temporal regulation of cardiac hypertrophic growth...
August 19, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28822826/depression-is-associated-with-the-long-term-outcome-of-lumbar-spinal-stenosis-surgery-a-10-year-follow-up-study
#19
Iina Tuomainen, Maarit Pakarinen, Timo Aalto, Sanna Sinikallio, Heikki Kröger, Heimo Viinamäki, Olavi Airaksinen
BACKGROUND CONTEXT: Depression is associated with greater postoperative disability in lumbar spinal stenosis (LSS) patients. No previous studies have reported the association in a 10-year follow-up. PURPOSE: To evaluate the association between preoperative and postoperative depressive symptoms and the surgical outcome among LSS patients in a 10-year follow-up. In addition, we examined the effects of the depressive burden on the surgical outcome. DESIGN: A prospective observational follow-up study...
August 16, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28822656/phenylephrine-infusion-impact-on-surgical-site-infections-after-lower-extremity-bypass-surgery
#20
Craig Curry, Jens Eldrup-Jorgensen, Janelle Richard, Michele C Siciliano, Wendy Y Craig
OBJECTIVE: Lower extremity bypass (LEB) operations have high rates of surgical site infections (SSI). Phenylephrine is a commonly used vasoconstrictor which may reduce skin blood flow and increase the likelihood of SSI in these patients. We studied the potential effect of phenylephrine infusion during LEB surgery on SSI. METHODS: LEB cases and their demographic data were identified through the Vascular Quality Initiative registry. SSI in this population was identified using the hospital epidemiology surveillance database...
August 16, 2017: Journal of Vascular Surgery
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