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https://www.readbyqxmd.com/read/28300204/non-invasive-aerosol-delivery-and-transport-of-gold-nanoparticles-to-the-brain
#1
Ramesh Raliya, Debajit Saha, Tandeep S Chadha, Baranidharan Raman, Pratim Biswas
Targeted delivery of nanoscale carriers containing packaged payloads to the central nervous system has potential use in many diagnostic and therapeutic applications. Moreover, understanding of the bio-interactions of the engineered nanoparticles used for tissue-specific delivery by non-invasive delivery approaches are also of paramount interest. Here, we have examined this issue systematically in a relatively simple invertebrate model using insects. We synthesized 5 nm, positively charged gold nanoparticles (AuNPs) and targeted their delivery using the electrospray aerosol generator...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28273047/sensing-of-single-electrons-using-micro-and-nano-technologies-a-review
#2
Jubayer Jalil, Yong Zhu, Chandima Ekanayake, Yong Ruan
During the last three decades, the remarkable dynamic features of microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS), and advances in solid-state electronics hold much potential for the fabrication of extremely sensitive charge sensors. These sensors have a broad range of applications, such as those involving the measurement of ionization radiation, detection of bio-analyte and aerosol particles, mass spectrometry, scanning tunneling microscopy, and quantum computation. Designing charge sensors (also known as charge electrometers) for electrometry is deemed significant because of the sensitivity and resolution issues in the range of micro- and nano-scales...
April 7, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28133538/aerosol-synthesis-of-phase-controlled-iron-graphene-nanohybrids-through-feooh-nanorod-intermediates
#3
X S Lv, Y Qiu, Z Y Wang, G M Jiang, Y T Chen, X H Xu, R H Hurt
Iron-based nanoparticles form the basis for a host of sustainable alternative technologies based on this earth-abundant, low-toxicity element that can adopt a variety of oxidation states, crystal phases, and functions. Control of size, shape, and phase stability is a challenge for many nano-iron-based technologies, especially those involving Fe(0) that is susceptible to oxidation under ambient conditions. This article presents a continuous method for hybridizing Fe-based nanoparticles with carbon in the form of graphene-encapsulated Fe-based particles with core-shell symmetry that allows flexible control of iron particle size, shape, and phase stability...
October 1, 2016: Environmental Science. Nano
https://www.readbyqxmd.com/read/28126628/investigation-of-discharged-aerosol-nanoparticles-during-chemical-precipitation-and-spray-pyrolysis-for-developing-safety-measures-in-the-nano-research-laboratory
#4
Еvgeny Kolesnikov, Gopalu Karunakaran, Anna Godymchuk, Levina Vera, Andrey Grigorjevich Yudin, Alexander Gusev, Denis Kuznetsov
Nowadays, the demands for the nanoparticles are increasing due to their tremendous applications in various fields. As a consequence, the discharge of nanoparticles into the atmosphere and environment is also increasing, posing a health threat and environmental damage in terms of pollution. Thus, an extensive research is essential to evaluate the discharge of these nanoparticles into the environment. Keeping this in mind, the present investigation aimed to analyze the discharge of aerosol nanoparticles that are synthesized in the laboratory via chemical precipitation and spray pyrolysis methods...
January 23, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28065572/uneven-distribution-of-inorganic-pollutants-in-marine-air-originating-from-ocean-going-ships
#5
László Bencs, Benjamin Horemans, Anna Jolanta Buczyńska, René Van Grieken
The distribution of mass, water-soluble inorganic salts and mineral elements of size-segregated aerosols (PM1, PM2.5-1 and PM10-2.5), precursor gaseous pollutants, black carbon, and nanoparticles (10-300 nm size range) at the Southern Bight of the North Sea has been studied. The concentrations of air pollutants peaked over shipping lanes, open-water anchorage areas and frequently navigated waters, due to the presence of mobile emission sources. A considerable decrease in air pollutant levels was seen when diverting from these marine areas towards remote or coastal banks...
March 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28011589/maternal-engineered-nanomaterial-exposure-disrupts-progeny-cardiac-function-and-bioenergetics
#6
Quincy A Hathaway, Cody E Nichols, Danielle L Shepherd, Phoebe A Stapleton, Sarah L Mclaughlin, Janelle C Stricker, Stephanie L Rellick, Mark V Pinti, Alaeddin B Abukabda, Carroll R McBride, Jinghai Yi, Seth M Stine, Timothy R Nurkiewicz, John M Hollander
Nanomaterial production is expanding as new industrial and consumer applications are introduced. Nevertheless, the impacts of exposure to these compounds are not fully realized. The current study was designed to determine whether gestational nano-TiO2 exposure impacts cardiac and metabolic function of developing progeny. Pregnant Sprague Dawley rats were exposed to nano-TiO2 aerosols (~10 mg/m(3), 130 - 150 nm count median aerodynamic diameter) for 7-8 non-consecutive days beginning at gestational day 5-6. Physiological and bioenergetic effects on heart function and cardiomyocytes across three time points: fetal (gestational day 20), neonatal (4-10 days), and young adult (6-12 weeks) were evaluated...
December 23, 2016: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28005381/molecular-characterization-of-organosulfur-compounds-in-biodiesel-and-diesel-fuel-secondary-organic-aerosol
#7
Sandra L Blair, Amanda C MacMillan, Greg T Drozd, Allen H Goldstein, Rosalie K Chu, Ljiljana Paša-Tolić, Jared B Shaw, Nikola Tolić, Peng Lin, Julia Laskin, Alexander Laskin, Sergey A Nizkorodov
Secondary organic aerosol (SOA), formed in the photooxidation of diesel fuel, biodiesel fuel, and 20% biodiesel fuel/80% diesel fuel mixture, are prepared under high-NOx conditions in the presence and absence of sulfur dioxide (SO2), ammonia (NH3), and relative humidity (RH). The composition of condensed-phase organic compounds in SOA is measured using several complementary techniques including aerosol mass spectrometry (AMS), high-resolution nanospray desorption electrospray ionization mass spectrometry (nano-DESI/HRMS), and ultrahigh resolution and mass accuracy 21T Fourier transform ion cyclotron resonance mass spectrometry (21T FT-ICR MS)...
January 3, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/27994523/estimation-of-radiological-dose-from-progeny-of-222-rn-and-220-rn-using-dtps-drps-and-wire-mesh-capped-progeny-sensors
#8
Rohit Mehra, Rajan Jakhu, Pargin Bangotra, Harish Mohan Mittal
Radon ((222)Rn) and its decay products are the major sources of natural radiation exposure to general population. The activity concentrations of unattached and attached short-lived (222)Rn and thoron ((220)Rn) progeny in indoor environment of some dwellings of the Jalandhar and Kapurthala districts of Punjab had been calculated using the deposition-based progeny sensors (DRPS/DTPS) and wire-mesh-capped (DRPS/DTPS) progeny sensors. The observed concentration of attached (222)Rn and (220)Rn progeny showed the variation from 5 to 21 Bq·m(-3) and 0...
October 2016: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/27919268/air-liquid-interface-exposure-to-aerosols-of-poorly-soluble-nanomaterials-induces-different-biological-activation-levels-compared-to-exposure-to-suspensions
#9
COMPARATIVE STUDY
Thomas Loret, Emmanuel Peyret, Marielle Dubreuil, Olivier Aguerre-Chariol, Christophe Bressot, Olivier le Bihan, Tanguy Amodeo, Bénédicte Trouiller, Anne Braun, Christophe Egles, Ghislaine Lacroix
BACKGROUND: Recently, much progress has been made to develop more physiologic in vitro models of the respiratory system and improve in vitro simulation of particle exposure through inhalation. Nevertheless, the field of nanotoxicology still suffers from a lack of relevant in vitro models and exposure methods to predict accurately the effects observed in vivo, especially after respiratory exposure. In this context, the aim of our study was to evaluate if exposing pulmonary cells at the air-liquid interface to aerosols of inhalable and poorly soluble nanomaterials generates different toxicity patterns and/or biological activation levels compared to classic submerged exposures to suspensions...
November 3, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27819297/stable-isotopes-measurements-reveal-dual-carbon-pools-contributing-to-organic-matter-enrichment-in-marine-aerosol
#10
Darius Ceburnis, Agne Masalaite, Jurgita Ovadnevaite, Andrius Garbaras, Vidmantas Remeikis, Willy Maenhaut, Magda Claeys, Jean Sciare, Dominique Baisnée, Colin D O'Dowd
Stable carbon isotope ratios in marine aerosol collected over the Southern Indian Ocean revealed δ(13)C values ranging from -20.0‰ to -28.2‰. The isotope ratios exhibited a strong correlation with the fractional organic matter (OM) enrichment in sea spray aerosol. The base-level isotope ratio of -20.0‰ is characteristic of an aged Dissolved Organic Matter (DOM) pool contributing a relatively homogeneous background level of DOM to oceanic waters. The range of isotope ratios, extending down to -28.2‰, is characteristic of more variable, stronger, and fresher Particulate Organic Matter (POM) pool driven by trophic level interactions...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27754970/markers-of-lipid-oxidative-damage-among-office-workers-exposed-intermittently-to-air-pollutants-including-nanotio2-particles
#11
Daniela Pelclova, Vladimir Zdimal, Petr Kacer, Martin Komarc, Zdenka Fenclova, Stepanka Vlckova, Nadezda Zikova, Jaroslav Schwarz, Otakar Makes, Tomas Navratil, Sergey Zakharov, Dhimiter Bello
Nanoscale titanium dioxide (nanoTiO2) is a commercially important nanomaterial used in numerous applications. Experimental studies with nanotitania have documented lung injury and inflammation, oxidative stress, and genotoxicity. Production workers in TiO2 manufacturing with a high proportion of nanoparticles and a mixture of other air pollutants, such as gases and organic aerosols, had increased markers of oxidative stress, including DNA and protein damage, as well as lipid peroxidation in their exhaled breath condensate (EBC) compared to unexposed controls...
March 1, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27637557/the-validity-and-applicability-of-using-a-generic-exposure-assessment-model-for-occupational-exposure-to-nano-objects-and-their-aggregates-and-agglomerates
#12
Cindy Bekker, Eef Voogd, Wouter Fransman, Roel Vermeulen
BACKGROUND: Control banding can be used as a first-tier assessment to control worker exposure to nano-objects and their aggregates and agglomerates (NOAA). In a second tier, more advanced modelling approaches are needed to produce quantitative exposure estimates. As currently no general quantitative nano-specific exposure models are available, this study evaluated the validity and applicability of using a generic exposure assessment model (the Advanced REACH Tool-ART) for occupational exposure to NOAA...
November 2016: Annals of Occupational Hygiene
https://www.readbyqxmd.com/read/27592719/silica-coated-nonstoichiometric-nano-zn-ferrites-for-magnetic-resonance-imaging-and-hyperthermia-treatment
#13
Fabian H L Starsich, Georgios A Sotiriou, Moritz C Wurnig, Christian Eberhardt, Ann M Hirt, Andreas Boss, Sotiris E Pratsinis
Large-scale and reproducible synthesis of nanomaterials is highly sought out for successful translation into clinics. Flame aerosol technology with its proven capacity to manufacture high purity materials (e.g., light guides) up to kg h(-1) is explored here for the preparation of highly magnetic, nonstoichiometric Zn-ferrite (Zn0.4 Fe2.6 O4 ) nanoparticles coated in situ with a nanothin SiO2 layer. The focus is on their suitability as magnetic multifunctional theranostic agents analyzing their T2 contrast enhancing capability for magnetic resonance imaging (MRI) and their magnetic hyperthermia performance...
September 5, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27580261/nanominerals-fullerene-aggregates-and-hazardous-elements-in-coal-and-coal-combustion-generated-aerosols-an-environmental-and-toxicological-assessment
#14
Jyotilima Saikia, Bardwi Narzary, Sonali Roy, Manobjyoti Bordoloi, Prasenjit Saikia, Binoy K Saikia
Studies on coal-derived nanoparticles as well as nano-minerals are important in the context of the human health and the environment. The coal combustion-generated aerosols also affect human health and environmental quality aspects in any coal-fired station. In this study, the feed coals and their combustion-generated aerosols from coal-fired boilers of two tea industry facilities were investigated for the presence of nanoparticles/nano minerals, fullerene aggregates, and potentially hazardous elements (PHEs)...
December 2016: Chemosphere
https://www.readbyqxmd.com/read/27538013/high-throughput-synthesis-of-lignin-particles-%C3%A2-30-nm-to-%C3%A2-2-%C3%AE-m-via-aerosol-flow-reactor-size-fractionation-and-utilization-in-pickering-emulsions
#15
Mariko Ago, Siqi Huan, Maryam Borghei, Janne Raula, Esko I Kauppinen, Orlando J Rojas
An aerosol flow reactor was used for the first time for high-throughput, high yield synthesis of spherical lignin particles with given inherent hydrophilicity, depending on the precursor biomolecule. In situ fractionation via Berner type impactor afforded populations with characteristic sizes ranging from ∼30 nm to 2 μm. The as-produced, dry lignin particles displayed excellent mechanical integrity, even after redispersion under high shear in either mineral oil or water. They were effective in the stabilization of oil-in-water (O/W) Pickering emulsions with tunable droplet size, depending on the dimension of the lignin particles used for emulsification...
September 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27447427/smoking-and-cerebral-oxidative-stress-and%C3%A2-air-pollution-a-dreadful-equation-with%C3%A2-particulate-matter-involved-and-one-more-powerful-reason-not-to-smoke-anything
#16
Lilian Calderón-Garcidueñas
Smoking has serious health effects. Cigarettes, including tobacco, marijuana, and electronic nicotine delivery systems are very effective ways to inhale harmful amounts of fine and ultrafine particulate matter. Does size matter? Yes, indeed! The smaller the particle you inhale, the higher the ability to produce reactive oxygen species and to readily access the brain. In this issue of the Journal of Alzheimer's Disease, Durazzo provides evidence of an association between active cigarette tobacco smoking in cognitively-normal elders and increased cerebral oxidative stress, while in actively smoking Alzheimer's disease (AD) patients, the association was also seen with smaller left and total hippocampal volumes...
July 22, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27356965/leukotrienes-in-exhaled-breath-condensate-and-fractional-exhaled-nitric-oxide-in-workers-exposed-to-tio2-nanoparticles
#17
Daniela Pelclova, Vladimir Zdimal, Petr Kacer, Zdenka Fenclova, Stepanka Vlckova, Martin Komarc, Tomas Navratil, Jaroslav Schwarz, Nadezda Zikova, Otakar Makes, Kamila Syslova, Jaroslav Belacek, Sergey Zakharov
Human health data regarding exposure to nanoparticles are extremely scarce and biomonitoring of exposure is lacking in spite of rodent pathological experimental data. Potential markers of the health-effects of engineered nanoparticles were examined in 30 workers exposed to TiO2 aerosol, 22 office employees of the same plant, and 45 unexposed controls. Leukotrienes (LT) B4, C4, E4, and D4 were analysed in the exhaled breath condensate (EBC) and urine via liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS)...
June 30, 2016: Journal of Breath Research
https://www.readbyqxmd.com/read/27321746/environmental-release-of-engineered-nanomaterials-from-commercial-tiles-under-standardized-abrasion-conditions
#18
Christophe Bressot, Nicolas Manier, Cécile Pagnoux, Olivier Aguerre-Chariol, Martin Morgeneyer
The study presented here focuses on commercial antibacterial tiles whose emissivity of (nano) particles due to abrasion has yet barely been investigated. The tiles have been characterized regarding their surface properties and composition throughout their chain-of-use, i.e. from their state of commercialization until the experimental end-of-service life. In contrast to plane standard tiles, their surfaces form hilly surfaces. In the depressions, titanium dioxide is found at the surface, thus theoretically protected by the hilly areas against abrasion on the tile's surface...
May 27, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27265937/-features-of-nano-aerosols-action-and-safety-measures
#19
L A Lutsenko, V N Rakitskiy, A V Il'nitskaya, A M Egorova, L L Gvozdeva
The article presents results of studies concerning influence of high-dispersed aerosol formed in traditional plasma processes on operators' health. Consideration also includes new technologies to obtain metall-containing nanoproducts; the authors recommend protection measures for workers, methods and devices to control nano aerosols in air.
2016: Meditsina Truda i Promyshlennaia Ekologiia
https://www.readbyqxmd.com/read/27234377/potential-release-of-manufactured-nano-objects-during-sanding-of-nano-coated-wood-surfaces
#20
Wouter Fransman, Cindy Bekker, Peter Tromp, Willem B Duis
Increasing production and applications of manufactured nano objects (MNOs) have become a source for human exposure and therefore raise concerns and questions about the possible health effects. In this study, the potential release of nano objects, their agglomerates, and aggregates (NOAA) as a result of sanding of hardwood treated with MNOs-containing coating was examined. Two types of MNO-containing coating were compared with untreated hardwood that allowed the evaluation of the influence of the chemical composition on the release of particles...
August 2016: Annals of Occupational Hygiene
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