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https://www.readbyqxmd.com/read/27919268/air-liquid-interface-exposure-to-aerosols-of-poorly-soluble-nanomaterials-induces-different-biological-activation-levels-compared-to-exposure-to-suspensions
#1
Thomas Loret, Emmanuel Peyret, Marielle Dubreuil, Olivier Aguerre-Chariol, Christophe Bressot, Olivier le Bihan, Tanguy Amodeo, Bénédicte Trouiller, Anne Braun, Christophe Egles, Ghislaine Lacroix
BACKGROUND: Recently, much progress has been made to develop more physiologic in vitro models of the respiratory system and improve in vitro simulation of particle exposure through inhalation. Nevertheless, the field of nanotoxicology still suffers from a lack of relevant in vitro models and exposure methods to predict accurately the effects observed in vivo, especially after respiratory exposure. In this context, the aim of our study was to evaluate if exposing pulmonary cells at the air-liquid interface to aerosols of inhalable and poorly soluble nanomaterials generates different toxicity patterns and/or biological activation levels compared to classic submerged exposures to suspensions...
November 3, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27819297/stable-isotopes-measurements-reveal-dual-carbon-pools-contributing-to-organic-matter-enrichment-in-marine-aerosol
#2
Darius Ceburnis, Agne Masalaite, Jurgita Ovadnevaite, Andrius Garbaras, Vidmantas Remeikis, Willy Maenhaut, Magda Claeys, Jean Sciare, Dominique Baisnée, Colin D O'Dowd
Stable carbon isotope ratios in marine aerosol collected over the Southern Indian Ocean revealed δ(13)C values ranging from -20.0‰ to -28.2‰. The isotope ratios exhibited a strong correlation with the fractional organic matter (OM) enrichment in sea spray aerosol. The base-level isotope ratio of -20.0‰ is characteristic of an aged Dissolved Organic Matter (DOM) pool contributing a relatively homogeneous background level of DOM to oceanic waters. The range of isotope ratios, extending down to -28.2‰, is characteristic of more variable, stronger, and fresher Particulate Organic Matter (POM) pool driven by trophic level interactions...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27754970/markers-of-lipid-oxidative-damage-among-office-workers-exposed-intermittently-to-air-pollutants-including-nanotio2-particles
#3
Daniela Pelclova, Vladimir Zdimal, Petr Kacer, Martin Komarc, Zdenka Fenclova, Stepanka Vlckova, Nadezda Zikova, Jaroslav Schwarz, Otakar Makes, Tomas Navratil, Sergey Zakharov, Dhimiter Bello
Nanoscale titanium dioxide (nanoTiO2) is a commercially important nanomaterial used in numerous applications. Experimental studies with nanotitania have documented lung injury and inflammation, oxidative stress, and genotoxicity. Production workers in TiO2 manufacturing with a high proportion of nanoparticles and a mixture of other air pollutants, such as gases and organic aerosols, had increased markers of oxidative stress, including DNA and protein damage, as well as lipid peroxidation in their exhaled breath condensate (EBC) compared to unexposed controls...
October 18, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27637557/the-validity-and-applicability-of-using-a-generic-exposure-assessment-model-for-occupational-exposure-to-nano-objects-and-their-aggregates-and-agglomerates
#4
Cindy Bekker, Eef Voogd, Wouter Fransman, Roel Vermeulen
BACKGROUND: Control banding can be used as a first-tier assessment to control worker exposure to nano-objects and their aggregates and agglomerates (NOAA). In a second tier, more advanced modelling approaches are needed to produce quantitative exposure estimates. As currently no general quantitative nano-specific exposure models are available, this study evaluated the validity and applicability of using a generic exposure assessment model (the Advanced REACH Tool-ART) for occupational exposure to NOAA...
September 16, 2016: Annals of Occupational Hygiene
https://www.readbyqxmd.com/read/27592719/silica-coated-nonstoichiometric-nano-zn-ferrites-for-magnetic-resonance-imaging-and-hyperthermia-treatment
#5
Fabian H L Starsich, Georgios A Sotiriou, Moritz C Wurnig, Christian Eberhardt, Ann M Hirt, Andreas Boss, Sotiris E Pratsinis
Large-scale and reproducible synthesis of nanomaterials is highly sought out for successful translation into clinics. Flame aerosol technology with its proven capacity to manufacture high purity materials (e.g., light guides) up to kg h(-1) is explored here for the preparation of highly magnetic, nonstoichiometric Zn-ferrite (Zn0.4 Fe2.6 O4 ) nanoparticles coated in situ with a nanothin SiO2 layer. The focus is on their suitability as magnetic multifunctional theranostic agents analyzing their T2 contrast enhancing capability for magnetic resonance imaging (MRI) and their magnetic hyperthermia performance...
September 5, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27580261/nanominerals-fullerene-aggregates-and-hazardous-elements-in-coal-and-coal-combustion-generated-aerosols-an-environmental-and-toxicological-assessment
#6
Jyotilima Saikia, Bardwi Narzary, Sonali Roy, Manobjyoti Bordoloi, Prasenjit Saikia, Binoy K Saikia
Studies on coal-derived nanoparticles as well as nano-minerals are important in the context of the human health and the environment. The coal combustion-generated aerosols also affect human health and environmental quality aspects in any coal-fired station. In this study, the feed coals and their combustion-generated aerosols from coal-fired boilers of two tea industry facilities were investigated for the presence of nanoparticles/nano minerals, fullerene aggregates, and potentially hazardous elements (PHEs)...
December 2016: Chemosphere
https://www.readbyqxmd.com/read/27538013/high-throughput-synthesis-of-lignin-particles-%C3%A2-30-nm-to-%C3%A2-2-%C3%AE-m-via-aerosol-flow-reactor-size-fractionation-and-utilization-in-pickering-emulsions
#7
Mariko Ago, Siqi Huan, Maryam Borghei, Janne Raula, Esko I Kauppinen, Orlando J Rojas
An aerosol flow reactor was used for the first time for high-throughput, high yield synthesis of spherical lignin particles with given inherent hydrophilicity, depending on the precursor biomolecule. In situ fractionation via Berner type impactor afforded populations with characteristic sizes ranging from ∼30 nm to 2 μm. The as-produced, dry lignin particles displayed excellent mechanical integrity, even after redispersion under high shear in either mineral oil or water. They were effective in the stabilization of oil-in-water (O/W) Pickering emulsions with tunable droplet size, depending on the dimension of the lignin particles used for emulsification...
September 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27447427/smoking-and-cerebral-oxidative-stress-and%C3%A2-air-pollution-a-dreadful-equation-with%C3%A2-particulate-matter-involved-and-one-more-powerful-reason-not-to-smoke-anything
#8
Lilian Calderón-Garcidueñas
Smoking has serious health effects. Cigarettes, including tobacco, marijuana, and electronic nicotine delivery systems are very effective ways to inhale harmful amounts of fine and ultrafine particulate matter. Does size matter? Yes, indeed! The smaller the particle you inhale, the higher the ability to produce reactive oxygen species and to readily access the brain. In this issue of the Journal of Alzheimer's Disease, Durazzo provides evidence of an association between active cigarette tobacco smoking in cognitively-normal elders and increased cerebral oxidative stress, while in actively smoking Alzheimer's disease (AD) patients, the association was also seen with smaller left and total hippocampal volumes...
July 22, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27356965/leukotrienes-in-exhaled-breath-condensate-and-fractional-exhaled-nitric-oxide-in-workers-exposed-to-tio2-nanoparticles
#9
Daniela Pelclova, Vladimir Zdimal, Petr Kacer, Zdenka Fenclova, Stepanka Vlckova, Martin Komarc, Tomas Navratil, Jaroslav Schwarz, Nadezda Zikova, Otakar Makes, Kamila Syslova, Jaroslav Belacek, Sergey Zakharov
Human health data regarding exposure to nanoparticles are extremely scarce and biomonitoring of exposure is lacking in spite of rodent pathological experimental data. Potential markers of the health-effects of engineered nanoparticles were examined in 30 workers exposed to TiO2 aerosol, 22 office employees of the same plant, and 45 unexposed controls. Leukotrienes (LT) B4, C4, E4, and D4 were analysed in the exhaled breath condensate (EBC) and urine via liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS)...
2016: Journal of Breath Research
https://www.readbyqxmd.com/read/27321746/environmental-release-of-engineered-nanomaterials-from-commercial-tiles-under-standardized-abrasion-conditions
#10
Christophe Bressot, Nicolas Manier, Cécile Pagnoux, Olivier Aguerre-Chariol, Martin Morgeneyer
The study presented here focuses on commercial antibacterial tiles whose emissivity of (nano) particles due to abrasion has yet barely been investigated. The tiles have been characterized regarding their surface properties and composition throughout their chain-of-use, i.e. from their state of commercialization until the experimental end-of-service life. In contrast to plane standard tiles, their surfaces form hilly surfaces. In the depressions, titanium dioxide is found at the surface, thus theoretically protected by the hilly areas against abrasion on the tile's surface...
May 27, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27265937/-features-of-nano-aerosols-action-and-safety-measures
#11
L A Lutsenko, V N Rakitskiy, A V Il'nitskaya, A M Egorova, L L Gvozdeva
The article presents results of studies concerning influence of high-dispersed aerosol formed in traditional plasma processes on operators' health. Consideration also includes new technologies to obtain metall-containing nanoproducts; the authors recommend protection measures for workers, methods and devices to control nano aerosols in air.
2016: Meditsina Truda i Promyshlennaia Ekologiia
https://www.readbyqxmd.com/read/27234377/potential-release-of-manufactured-nano-objects-during-sanding-of-nano-coated-wood-surfaces
#12
Wouter Fransman, Cindy Bekker, Peter Tromp, Willem B Duis
Increasing production and applications of manufactured nano objects (MNOs) have become a source for human exposure and therefore raise concerns and questions about the possible health effects. In this study, the potential release of nano objects, their agglomerates, and aggregates (NOAA) as a result of sanding of hardwood treated with MNOs-containing coating was examined. Two types of MNO-containing coating were compared with untreated hardwood that allowed the evaluation of the influence of the chemical composition on the release of particles...
August 2016: Annals of Occupational Hygiene
https://www.readbyqxmd.com/read/27225126/the-role-of-low-volatility-organic-compounds-in-initial-particle-growth-in-the-atmosphere
#13
Jasmin Tröstl, Wayne K Chuang, Hamish Gordon, Martin Heinritzi, Chao Yan, Ugo Molteni, Lars Ahlm, Carla Frege, Federico Bianchi, Robert Wagner, Mario Simon, Katrianne Lehtipalo, Christina Williamson, Jill S Craven, Jonathan Duplissy, Alexey Adamov, Joao Almeida, Anne-Kathrin Bernhammer, Martin Breitenlechner, Sophia Brilke, Antònio Dias, Sebastian Ehrhart, Richard C Flagan, Alessandro Franchin, Claudia Fuchs, Roberto Guida, Martin Gysel, Armin Hansel, Christopher R Hoyle, Tuija Jokinen, Heikki Junninen, Juha Kangasluoma, Helmi Keskinen, Jaeseok Kim, Manuel Krapf, Andreas Kürten, Ari Laaksonen, Michael Lawler, Markus Leiminger, Serge Mathot, Ottmar Möhler, Tuomo Nieminen, Antti Onnela, Tuukka Petäjä, Felix M Piel, Pasi Miettinen, Matti P Rissanen, Linda Rondo, Nina Sarnela, Siegfried Schobesberger, Kamalika Sengupta, Mikko Sipilä, James N Smith, Gerhard Steiner, Antònio Tomè, Annele Virtanen, Andrea C Wagner, Ernest Weingartner, Daniela Wimmer, Paul M Winkler, Penglin Ye, Kenneth S Carslaw, Joachim Curtius, Josef Dommen, Jasper Kirkby, Markku Kulmala, Ilona Riipinen, Douglas R Worsnop, Neil M Donahue, Urs Baltensperger
About half of present-day cloud condensation nuclei originate from atmospheric nucleation, frequently appearing as a burst of new particles near midday. Atmospheric observations show that the growth rate of new particles often accelerates when the diameter of the particles is between one and ten nanometres. In this critical size range, new particles are most likely to be lost by coagulation with pre-existing particles, thereby failing to form new cloud condensation nuclei that are typically 50 to 100 nanometres across...
May 26, 2016: Nature
https://www.readbyqxmd.com/read/27197574/the-effect-of-acid-base-clustering-and-ions-on-the-growth-of-atmospheric-nano-particles
#14
Katrianne Lehtipalo, Linda Rondo, Jenni Kontkanen, Siegfried Schobesberger, Tuija Jokinen, Nina Sarnela, Andreas Kürten, Sebastian Ehrhart, Alessandro Franchin, Tuomo Nieminen, Francesco Riccobono, Mikko Sipilä, Taina Yli-Juuti, Jonathan Duplissy, Alexey Adamov, Lars Ahlm, João Almeida, Antonio Amorim, Federico Bianchi, Martin Breitenlechner, Josef Dommen, Andrew J Downard, Eimear M Dunne, Richard C Flagan, Roberto Guida, Jani Hakala, Armin Hansel, Werner Jud, Juha Kangasluoma, Veli-Matti Kerminen, Helmi Keskinen, Jaeseok Kim, Jasper Kirkby, Agnieszka Kupc, Oona Kupiainen-Määttä, Ari Laaksonen, Michael J Lawler, Markus Leiminger, Serge Mathot, Tinja Olenius, Ismael K Ortega, Antti Onnela, Tuukka Petäjä, Arnaud Praplan, Matti P Rissanen, Taina Ruuskanen, Filipe D Santos, Simon Schallhart, Ralf Schnitzhofer, Mario Simon, James N Smith, Jasmin Tröstl, Georgios Tsagkogeorgas, António Tomé, Petri Vaattovaara, Hanna Vehkamäki, Aron E Vrtala, Paul E Wagner, Christina Williamson, Daniela Wimmer, Paul M Winkler, Annele Virtanen, Neil M Donahue, Kenneth S Carslaw, Urs Baltensperger, Ilona Riipinen, Joachim Curtius, Douglas R Worsnop, Markku Kulmala
The growth of freshly formed aerosol particles can be the bottleneck in their survival to cloud condensation nuclei. It is therefore crucial to understand how particles grow in the atmosphere. Insufficient experimental data has impeded a profound understanding of nano-particle growth under atmospheric conditions. Here we study nano-particle growth in the CLOUD (Cosmics Leaving OUtdoors Droplets) chamber, starting from the formation of molecular clusters. We present measured growth rates at sub-3 nm sizes with different atmospherically relevant concentrations of sulphuric acid, water, ammonia and dimethylamine...
May 20, 2016: Nature Communications
https://www.readbyqxmd.com/read/27187980/nanoscale-particulate-matter-from-urban-traffic-rapidly-induces-oxidative-stress-and-inflammation-in-olfactory-epithelium-with-concomitant-effects-on-brain
#15
Hank Cheng, Arian Saffari, Constantinos Sioutas, Henry J Forman, Todd E Morgan, Caleb E Finch
BACKGROUND: Rodent models for urban air pollution show consistent induction of inflammatory responses in major brain regions. However, the initial impact of air pollution particulate material on olfactory gateways has not been reported. OBJECTIVE: We evaluated the olfactory neuroepithelium (OE) and brain regional responses to a nanosized subfraction of urban traffic ultrafine particulate matter (nPM, < 200 nm) in vivo, ex vivo, and in vitro. METHODS: Adult mice were exposed to reaerosolized nPM for 5, 20, and 45 cumulative hours over 3 weeks...
October 2016: Environmental Health Perspectives
https://www.readbyqxmd.com/read/27181617/size-resolved-source-emission-rates-of-indoor-ultrafine-particles-considering-coagulation
#16
Donghyun Rim, Jung-Il Choi, Lance A Wallace
Indoor ultrafine particles (UFP, <100 nm) released from combustion and consumer products lead to elevated human exposure to UFP. UFP emitted from the sources undergo aerosol transformation processes such as coagulation and deposition. The coagulation effect can be significant during the source emission due to high concentration and high mobility of nanosize particles. However, few studies have estimated size-resolved UFP source emission strengths while considering coagulation in their theoretical and experimental research work...
September 20, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27163232/pomegranate-structured-conversion-reaction-cathode-with-a-built-in-li-source-for-high-energy-li-ion-batteries
#17
Xiulin Fan, Yujie Zhu, Chao Luo, Liumin Suo, Yan Lin, Tao Gao, Kang Xu, Chunsheng Wang
Transition metal fluorides (such as FeF3 or CoF2) promise significantly higher theoretical capacities (>571 mAh g(-1)) than the cathode materials currently used in Li-ion batteries. However, their practical application faces major challenges that include poor electrochemical reversibility induced by the repeated bond-breaking and formation and the accompanied volume changes and the difficulty of building an internal Li source within the material so that a full Li-ion cell could be assembled at a discharged state without inducing further technical risk and cost issues...
May 24, 2016: ACS Nano
https://www.readbyqxmd.com/read/27146638/real-time-measurement-of-electronic-cigarette-aerosol-size-distribution-and-metals-content-analysis
#18
Vladimir B Mikheev, Marielle C Brinkman, Courtney A Granville, Sydney M Gordon, Pamela I Clark
INTRODUCTION: Electronic cigarette (e-cigarette) use is increasing worldwide and is highest among both daily and nondaily smokers. E-cigarettes are perceived as a healthier alternative to combustible tobacco products, but their health risk factors have not yet been established, and one of them is lack of data on aerosol size generated by e-cigarettes. METHODS: We applied a real-time, high-resolution aerosol differential mobility spectrometer to monitor the evolution of aerosol size and concentration during puff development...
September 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27143100/molecular-composition-of-organic-aerosols-at-urban-background-and-road-tunnel-sites-using-ultra-high-resolution-mass-spectrometry
#19
Haijie Tong, Ivan Kourtchev, Pallavi Pant, Ian J Keyte, Ian P O'Connor, John C Wenger, Francis D Pope, Roy M Harrison, Markus Kalberer
Organic aerosol composition in the urban atmosphere is highly complex and strongly influenced by vehicular emissions which vary according to the make-up of the vehicle fleet. Normalized test measurements do not necessarily reflect real-world emission profiles and road tunnels are therefore ideal locations to characterise realistic traffic particle emissions with minimal interference from other particle sources and from atmospheric aging processes affecting their composition. In the current study, the composition of fine particles (diameter ≤2...
July 18, 2016: Faraday Discussions
https://www.readbyqxmd.com/read/27137954/the-characterisation-of-diesel-exhaust-particles-composition-size-distribution-and-partitioning
#20
Mohammed S Alam, Soheil Zeraati-Rezaei, Christopher P Stark, Zhirong Liang, Hongming Xu, Roy M Harrison
A number of major research questions remain concerning the sources and properties of road traffic generated particulate matter. A full understanding of the composition of primary vehicle exhaust aerosol and its contribution to secondary organic aerosol (SOA) formation still remains elusive, and many uncertainties exist relating to the semi-volatile component of the particles. Semi-Volatile Organic Compounds (SVOCs) are compounds which partition directly between the gas and aerosol phases under ambient conditions...
July 18, 2016: Faraday Discussions
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