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screening rheumatic heart disease

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https://www.readbyqxmd.com/read/28405228/normal-echocardiographic-mitral-and-aortic-valve-thickness-in-children
#1
Rachel H Webb, Nicola Culliford-Semmens, Karishma Sidhu, Nigel J Wilson
OBJECTIVE: We aimed to define the normal range of aortic and mitral valve thickness in healthy schoolchildren from a high prevalence rheumatic heart disease (RHD) region, using a standardised protocol for imaging and measurement. METHODS: Measurements were performed in 288 children without RHD. Anterior mitral valve leaflet (AMVL) thickness measurements were performed at the midpoint and tip of the leaflet in the parasternal long axis (PSLA) in diastole, when the AMVL was approximately parallel to the ventricular septum...
2017: Heart Asia
https://www.readbyqxmd.com/read/28400121/clinical-outcomes-for-young-people-with-screening-detected-and-clinically-diagnosed-rheumatic-heart-disease-in-fiji
#2
Daniel Engelman, Reapi L Mataika, Maureen Ah Kee, Susan Donath, Tom Parks, Samantha M Colquhoun, Jonathan R Carapetis, Joseph H Kado, Andrew C Steer
BACKGROUND: Echocardiographic screening is under consideration as a disease control strategy for rheumatic heart disease (RHD). However, clinical outcomes of young people with screening-detected RHD are unknown. We aimed to describe the outcomes for a cohort with screening-detected RHD, in comparison to patients with clinically-diagnosed RHD. METHODS: A retrospective cohort study included all young people with screening-detected RHD in the Central Division of Fiji in the primary cohort...
April 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28255081/clinical-impact-and-costs-of-echocardiographic-screening-for-rheumatic-heart-disease
#3
EDITORIAL
James N Kirkpatrick, Catherine M Otto
No abstract text is available yet for this article.
March 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28255077/echocardiographic-screening-for-rheumatic-heart-disease-in-indigenous-australian-children-a-cost-utility-analysis
#4
Kathryn Roberts, Jeffrey Cannon, David Atkinson, Alex Brown, Graeme Maguire, Bo Remenyi, Gavin Wheaton, Elizabeth Geelhoed, Jonathan R Carapetis
BACKGROUND: Rheumatic heart disease (RHD) remains a leading cause of cardiovascular morbidity and mortality in children and young adults in disadvantaged populations. The emergence of echocardiographic screening provides the opportunity for early disease detection and intervention. Using our own multistate model of RHD progression derived from Australian RHD register data, we performed a cost-utility analysis of echocardiographic screening in indigenous Australian children, with the dual aims of informing policy decisions in Australia and providing a model that could be adapted in other countries...
March 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28242246/the-value-of-the-score-for-the-targeting-of-atrial-fibrillation-staf-screening-in-acute-stroke-patients
#5
Xiao-Yan Liu, Yong-Xin Li, Yao-Gao Fu, Ye-Yan Cai, Yu-Sheng Zhang, Jiang-Yong Min, An-Ding Xu
BACKGROUND AND PURPOSE: Recently, the score for the targeting of atrial fibrillation (STAF) was introduced to identify the risk of atrial fibrillation (AF) in stroke patients. In this study, we aim to evaluate the usefulness of the STAF score for AF screening in acute stroke patients. METHODS: Patients with acute ischemic stroke who were admitted to our stroke unit were prospectively enrolled from March 2011 to March 2013. Baseline National Institutes of Health Stroke Scale (NIHSS), left atrial dilatation, and vascular etiology were assessed to calculate the STAF score...
February 24, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28202021/-i-passed-the-test-evidence-of-diagnostic-misconception-in-the-recruitment-of-population-controls-for-an-h3africa-genomic-study-in-cape-town-south-africa
#6
Francis Masiye, Bongani Mayosi, Jantina de Vries
BACKGROUND: Advances in genetic and genomic research have introduced challenges in obtaining informed consent for research in low and middle-income settings. However, there are only few studies that have explored challenges in obtaining informed consent in genetic and genomic research in Africa and none in South Africa. To start filling this gap, we conducted an empirical study to investigate the efficacy of informed consent procedures for an H3Africa genomic study on Rheumatic Heart Disease (RHDGen) at the University of Cape Town in South Africa...
February 15, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28163427/rheumatic-heart-disease-screening-current-concepts-and-challenges
#7
REVIEW
Scott Dougherty, Maziar Khorsandi, Philip Herbst
Rheumatic heart disease (RHD) is a disease of poverty, is almost entirely preventable, and is the most common cardiovascular disease worldwide in those under 25 years. RHD is caused by acute rheumatic fever (ARF) which typically results in cumulative valvular lesions that may present clinically after a number of years of subclinical disease. Therapeutic interventions, therefore, typically focus on preventing subsequent ARF episodes (with penicillin prophylaxis). However, not all patients with ARF develop symptoms and not all symptomatic cases present to a physician or are correctly diagnosed...
January 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28148989/nano-au-cmwcnt-modified-speb-gene-specific-amperometric-sensor-for-rapidly-detecting-streptococcus-pyogenes-causing-rheumatic-heart-disease
#8
Ankur Kaushal, Swati Singh, Ashok Kumar, Dinesh Kumar
A specific 5' NH2 labeled DNA probe of speB gene was immobilized onto the gold nanoparticles/carboxylated multi walled carbon nanotubes (Nano-Au/cMWCNT) screen printed electrode using EDC/NHS cross linking chemistry. This was followed by hybridization with 0.5-50 ng/6 µl of single stranded genomic DNA Streptococcus pyogenes infected patient throat swab samples. Electrochemical amperometric assay was deciphered by using cyclic voltammetry (CV) with methylene blue a redox indicator. The sensor had a sensitivity of 104...
March 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/28148987/gene-specific-impedimetric-bacterial-dna-sensor-for-rheumatic-heart-disease
#9
Swati Singh, Ankur Kaushal, Sunil Gupta, Ashok Kumar
An impedimetric mga gene specific DNA sensor was developed by immobilization of single stranded DNA probe onto the screen printed modified gold-dendrimer nanohybrid composite electrode for early and rapid detection of S. pyogenes in human throat swab samples causing rheumatic heart disease. Electrochemical impedance response was measured after hybridization with bacterial single stranded genomic DNA (ssG-DNA) with probe. The sensor was found highly specific to S. pyogenes and can detect as low as 0.01 ng ssDNA in 6 µL sample only in 30 min...
March 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/28117248/characteristics-aetiological-spectrum-and-management-of-valvular-heart-disease-in-a-tunisian-cardiovascular-centre
#10
Faten Triki, Jihen Jdidi, Dorra Abid, Nada Tabbabi, Selma Charfeddine, Sahar Ben Kahla, Mourad Hentati, Leila Abid, Samir Kammoun
BACKGROUND: Valvular heart diseases occur frequently in Tunisia, but no precise statistics are available. AIM: To analyse the characteristics of patients with abnormal valvular structure and function, and to identify the aetiological spectrum, treatment and outcomes of valvular heart disease in a single cardiovascular centre in Tunisia. METHODS: This retrospective study included patients with abnormal valvular structure and function, who were screened by transthoracic echocardiography at a single cardiology department between January 2010 and December 2013...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28088920/cardiac-strain-findings-in-children-with-latent-rheumatic-heart-disease-detected-by-echocardiographic-screening
#11
Andrea Beaton, Hedda Richards, Michelle Ploutz, Lasya Gaur, Twalib Aliku, Peter Lwabi, Greg Ensing, Craig Sable
BACKGROUND: Identification of patients with latent rheumatic heart disease by echocardiography presents a unique opportunity to prevent disease progression. Myocardial strain is a more sensitive indicator of cardiac performance than traditional measures of systolic function. OBJECTIVE: The objective of this study was to test the hypothesis that abnormalities in myocardial strain may be present in children with latent rheumatic heart disease. METHODS: Standard echocardiography images with electrocardiogram gating were obtained from Ugandan children found to have latent rheumatic heart disease as well as control subjects...
January 16, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/27989261/task-shifting-to-clinical-officer-led-echocardiography-screening-for-detecting-rheumatic-heart-disease-in-malawi-africa
#12
Amy Sims Sanyahumbi, Craig A Sable, Melissa Karlsten, Mina C Hosseinipour, Peter N Kazembe, Charles G Minard, Daniel J Penny
BACKGROUND: Echocardiographic screening for rheumatic heart disease in asymptomatic children may result in early diagnosis and prevent progression. Physician-led screening is not feasible in Malawi. Task shifting to mid-level providers such as clinical officers may enable more widespread screening. Hypothesis With short-course training, clinical officers can accurately screen for rheumatic heart disease using focussed echocardiography. METHODS: A total of eight clinical officers completed three half-days of didactics and 2 days of hands-on echocardiography training...
December 19, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27933106/screening-detected-rheumatic-heart-disease-can-progress-to-severe-disease
#13
Daniel Engelman, Gavin R Wheaton, Reapi L Mataika, Joseph H Kado, Samantha M Colquhoun, Bo Remenyi, Andrew C Steer
OBJECTIVES: Echocardiography is a sensitive test for rheumatic heart disease (RHD) screening; however the natural history of RHD detected on screening has not been established. We aimed to evaluate the progression of screening-detected RHD in Fiji. METHODS: All young people previously diagnosed with RHD through screening, with echocardiograms available for review, were eligible. All baseline echocardiograms were reported again. Participants underwent follow-up echocardiography...
2016: Heart Asia
https://www.readbyqxmd.com/read/27883978/outcomes-of-borderline-rheumatic-heart-disease-a-prospective-cohort-study
#14
Geneviève Bertaina, Bernard Rouchon, Bertrand Huon, Nina Guillot, Corinne Robillard, Baptiste Noël, Marie Nadra, Christophe Tribouilloy, Eloi Marijon, Xavier Jouven, Mariana Mirabel
CONTEXT AND AIMS: The advent of systematic screening for rheumatic heart disease (RHD) by echocardiography in endemic regions has led to a new entity: borderline RHD. The pathogenicity and natural history of borderline RHD needs to be addressed. The aim of this study was to assess the outcomes of children detected by echocardiography as having borderline RHD. METHODS: Schoolchildren in 4th grade (i.e., aged 9-10years) who were prospectively echo-screened for RHD (2012-2014) in Nouméa, New Caledonia, were asked to participate...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27815494/telehealth-solutions-to-enable-global-collaboration-in-rheumatic-heart-disease-screening
#15
Eduardo Lv Lopes, Andrea Z Beaton, Bruno R Nascimento, Alison Tompsett, Julia Pa Dos Santos, Lindsay Perlman, Adriana C Diamantino, Kaciane Kb Oliveira, Cassio M Oliveira, Maria do Carmo P Nunes, Leonardo Bonisson, Antônio Lp Ribeiro, Craig Sable
BACKGROUND: The global burden of rheumatic heart disease is nearly 33 million people. Telemedicine, using cloud-server technology, provides an ideal solution for sharing images performed by non-physicians with cardiologists who are experts in rheumatic heart disease. OBJECTIVE: We describe our experience in using telemedicine to support a large rheumatic heart disease outreach screening programme in the Brazilian state of Minas Gerais. METHODS: The Programa de Rastreamento da Valvopatia Reumática (PROVAR) is a prospective cross-sectional study aimed at gathering epidemiological data on the burden of rheumatic heart disease in Minas Gerais and testing of a non-expert, telemedicine-supported model of outreach rheumatic heart disease screening...
November 4, 2016: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/27793430/the-heart-of-africa-succeeding-against-the-odds
#16
COMMENT
Karen Sliwa
South Africa and other areas of sub-Saharan Africa have in the past 20 years undergone rapid demographical changes, largely due to urbanisation and changes in lifestyle. This rapid change has led to a marked increase in specific cardiac conditions, such as hypertensive heart disease and coronary artery disease (with the highest prevalence in the middle-aged population), in conjunction with a range of other heart diseases, which are historically common in Africa-eg, rheumatic heart disease, cardiomyopathies, and unoperated congenital heart disease...
December 17, 2016: Lancet
https://www.readbyqxmd.com/read/27730711/adherence-to-secondary-antibiotic-prophylaxis-for-patients-with-rheumatic-heart-disease-diagnosed-through-screening-in-fiji
#17
Daniel Engelman, Reapi L Mataika, Joseph H Kado, Maureen Ah Kee, Susan Donath, Tom Parks, Andrew C Steer
OBJECTIVES: Echocardiographic screening for rheumatic heart disease (RHD) can detect subclinical cases; however, adequate adherence to secondary antibiotic prophylaxis (SAP) is required to alter disease outcomes. We aimed to investigate the adherence to SAP among young people with RHD diagnosed through echocardiographic screening in Fiji and to investigate factors associated with adherence. METHODS: Patients diagnosed with RHD through echocardiographic screening in Fiji from 2006 to 2014 were included...
December 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27619043/prevalence-of-rheumatic-heart-disease-in-patients-with-recurrent-tonsillitis-and-elevated-anti-streptolysin-o-titers
#18
M S Sahin, M U Yalcin, D Kocyigit
INTRODUCTION: Patients with elevated anti-streptolysin O (ASO) titers (ASOT) and recurrent tonsillitis episodes are known to be at higher risk for rheumatic heart disease (RHD). However, there is no data regarding prevalence of RHD in this high risk population. In this study, we aimed to screen ambulatory patients with elevated ASOT and recurrent tonsillitis episodes using echocardiography for identification of RHD. We hypothesized that prevalence of RHD is higher in this patient group compared to general population...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27566329/rheumatic-heart-disease-in-the-twenty-first-century
#19
REVIEW
Bethel Woldu, Gerald S Bloomfield
Rheumatic heart disease (RHD) is a chronic valvular disease resulting after severe or repetitive episodes of acute rheumatic fever (ARF), an autoimmune response to group A Streptococcus infection. RHD has been almost eliminated with improved social and health infrastructure in affluent countries while it remains a neglected disease with major cause of morbidity and mortality in many low- and middle-income countries, and resource-limited regions of high-income countries. Despite our evolving understanding of the pathogenesis of RHD, there have not been any significant advances to prevent or halt progression of disease in recent history...
October 2016: Current Cardiology Reports
https://www.readbyqxmd.com/read/27541662/clinical-and-geographic-patterns-of-rheumatic-heart-disease-in-outpatients-attending-cardiology-clinic-in-western-kenya
#20
Rebecca H Lumsden, Constantine Akwanalo, Stella Chepkwony, Anne Kithei, Vincent Omollo, Thomas L Holland, Gerald S Bloomfield, Wendy P O'Meara
INTRODUCTION: Rheumatic heart disease (RHD) remains a leading cause of cardiovascular mortality in sub-Saharan Africa. Identifying high risk populations and geographic patterns of disease is crucial to developing RHD prevention and screening strategies in endemic areas. OBJECTIVES: To identify clinical and geographical trends in RHD throughout western Kenya METHODS: We conducted a retrospective chart review of all patients <50years old attending adult cardiology clinic at a national referral hospital in western Kenya...
November 15, 2016: International Journal of Cardiology
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