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https://www.readbyqxmd.com/read/28934687/the-role-of-thiocyanate-in-enhancing-the-process-of-sulfite-reducing-cr-vi-by-inhibiting-the-formation-of-reactive-oxygen-species
#1
Bo Jiang, Shuaishuai Xin, Yijie Liu, Haihong He, Lin Li, Yizhen Tang, Siyi Luo, Xuejun Bi
The reductive detoxification of Cr(VI) by sulfite is known as the prevailing strategy and can be successfully implemented for the treatment of Cr(VI)-contaminated waters. However, this method inevitably faces the challenges of excessive consumption of sulfite due to the generations of highly oxidative OH and SO4(-) during the process of sulfite reducing Cr(VI). In this study, we find that a small quantity of thiocyanate (SCN) can catalytically enhance the process efficiency of Cr(VI) reduction by sulfite and effectively prevent the excessive consumption of sulfite...
September 12, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28933728/the-effect-of-astaxanthin-rich-microalgae-haematococcus-pluvialis-and-wholemeal-flours-incorporation-in-improving-the-physical-and-functional-properties-of-cookies
#2
A K M Mofasser Hossain, Margaret A Brennan, Susan L Mason, Xinbo Guo, Xin An Zeng, Charles S Brennan
Marine-based food supplements can improve human nutrition. In an effort to modulate glycaemic response and enhance nutritional aspects, marine-derived algal food rich in astaxanthin was used in the formulation of a model food (wholemeal cookie). Astaxanthin substitution of cookies made from three flours (wheat, barley and oat) demonstrated a significant reduction in the rate of glucose released during in vitro digestion together with an increase in the total phenolic content (TPC) and antioxidant capacity of the food...
July 26, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28933366/the-role-of-the-mapk-signaling-topoisomerase-and-dietary-bioactives-in-controlling-cancer-incidence
#3
REVIEW
Khaled A Selim, Hend Abdelrasoul, Mohamed Aboelmagd, Ahmed M Tawila
Reactive oxygen species (ROS) are common products of mitochondrial oxidative phosphorylation, xenobiotics metabolism and are generated in response to several environmental stress conditions. Some of them play important biochemical roles in cellular signal transduction and gene transcription. On the other hand, ROS are known to be involved in a wide range of human diseases, including cancer. The excessive production of such ROS together with disruption of homeostasis detoxifying mechanisms can mediate a series of cellular oxidative stresses...
April 26, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/28933362/male-infertility-the-effect-of-natural-antioxidants-and-phytocompounds-on-seminal-oxidative-stress
#4
REVIEW
Malik Adewoyin, Muhammad Ibrahim, Ramli Roszaman, Muhammad Lokman Md Isa, Nur Aizura Mat Alewi, Ainin Azwani Abdul Rafa, Mohd Nur Nasyriq Anuar
Defective sperm function has been identified as the most common cause of infertility. The objective of this study was to review recent findings on the effects of various antioxidants on male fertility. High amounts of poly unsaturated fatty acid are found in the mammalian spermatozoa membranes, thereby making them susceptible to lipid peroxidation. Although, free radicals and reactive oxygen species (ROS) play major roles in reproduction, they are strongly associated with oxidative stress. Furthermore, factors such as obesity, inflammation, pollutants and cigarette smoking are negatively correlated with spermatogenesis...
March 1, 2017: Diseases (Basel)
https://www.readbyqxmd.com/read/28933303/cardioprotective-potential-of-iron-chelators-and-prochelators
#5
Hana Jansova, Tomas Simunek
Heart is a particularly sensitive organ to iron overload and cardiomyopathy due to the excessive cardiac iron deposition causes most deaths in disorders such as beta-thalassemia major. Free or loosely bound iron ions readily cycle between ferrous and ferric states and catalyze Haber-Weiss reaction that yields highly reactive and toxic hydroxyl radicals. Treatment with iron chelators (desferrioxamine, deferiprone, and deferasirox) substantially improved cardiovascular morbidity and mortality in iron overloaded patients...
September 20, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28932691/percutaneous-nephrolithotomy-ileal-conduit-lithotripsy-and-litholapaxy-for-a-neglected-encrusted-ureteral-stent
#6
Andrés Gutierrez, Julián Chavarriaga, María A Ocampo, Carlos Hernandez
Urolithiasis can result as a complication of urinary diversión, favored by urinary stasis, intestinal mucus, urinary tract bacteriuria, the metabolic derangements and the presence of foreign bodies. We present a 52- year-old male who underwent radical cystectomy with construction of a Bricker uretero-ileostomy. 5 years later he was found with a forgotten ureteral stent, a 6 cm calculi occupying the whole ileal conduit and a 13 mm calculi in the left renal pelvis. We present our experience in the successful endourological management of an encrusted neglected ureteral stent in an ileal conduit, achieving a stone-free status without complications...
November 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28932301/melatonin-level-variations-with-different-behavioural-risk-factors-in-obese-female-patients
#7
Ana Malazonia, Tamar Zerekidze, Elen Giorgadze, Natia Chkheidze, Ketevan Asatiani
AIM: The role of behavioural factors and sleep duration and quality is important in the pathogenesis of obesity. The aim of our study was to evaluate the effects of behavioural risk factors on melatonin secretion in women. SUBJECTS AND METHODS: In total, 120 female patients were enrolled in the study and divided into two groups according to the body mass index. Detailed history, anthropometric measurements, urine and blood samples were evaluated for each patient...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28930821/sonographic-image-of-cervix-epithelioid-trophoblastic-tumor-coexisting-with-mucinous-adenocarcinoma-in-a-postmenopausal-woman-a-case-report
#8
Yi Zhu, Guo-Nan Zhang, Rui-Bo Zhang, Yu Shi, Deng-Feng Wang, Rong He
RATIONALE: Epithelioid trophoblastic tumor (ETT) is a distinctive but rare gestational trophoblastic neoplasia (GTN) composed of chorionic-type intermediate trophoblast cells. Approximately 50% ETT arose from the uterine cervix or lower uterine segment following a previous pregnancy with vaginal bleeding. With its unusual ability to simulate an invasive epithelioid neoplasm, ETT frequently poses a diagnostic challenge, especially involving the uterine cervix. PATIENT CONCERNS: We herein report the case of a 60-year-old female with persistent vaginal bleeding and middle-level elevation of serum human chorionic gonadotropin (hCG)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930810/oncological-outcomes-of-stage-ii-endometrial-cancer-a-retrospective-analysis-of-250-cases
#9
Nejat Ozgul, Gokhan Boyraz, Mehmet Coskun Salman, Murat Gultekin, Kunter Yuce, Akbar Ibrahimov, Anil Erturk, Kemal Gungorduk, Varol Gulseren, Muzaffer Sanci, Osman Turkmen, Alper Karalok, Gunsu Kimyon, Taner Turan, Nazli Topfedaisi Ozkan, Mehmet Mutlu Meydanli, Tayfun Gungor, Hulya Ayik, Tayup Simsek
OBJECTIVE: The aim of this study was to investigate the effect of different surgical approaches, adjuvant therapy, and pathological characteristics on oncological outcomes in patients with 2009 International Federation of Gynecology and Obstetrics (FIGO) stage II endometrial cancer (EC). METHODS: A multicenter, retrospective department database review was performed to identify patients with FIGO 2009 stage II EC who underwent surgical staging between 2002 and 2015 at 5 gynecologic oncology centers in Turkey...
September 19, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28930578/identification-of-bioactive-glucose-lowering-compounds-of-methanolic-extract-of-hodgsonia-heteroclita-fruit-pulp
#10
Talambedu Usha, Arvind Kumar Goyal, Derhasat Narzary, Lokesh Prakash, Gulshan Wadhwa, Dinesh Babu, Divya Shanmugarajan, Sushil Kumar Middha
We have investigated the anti-oxidative and glucose-lowering effects of 70% methanolic extract of H. heteroclita fruit pulp (MHE). Anti-oxidative property of MHE was assessed by free radical scavenging assays and compound level screening by LC-MS profiling. In silico analysis and in vivo preclinical validation were also performed using molecular docking and alloxan-induced diabetic model, respectively. MHE showed high anti-oxidant activity in DPPH radical scavenging assay with an IC50 of 0.37 μg/mL. The LC-MS profile of MHE substantiated the presence of p-hydroxy acids including benzoic, salicylic, p-coumaric, o-coumaric, caffeic, protocatechuic, gentisic, 2,4-dihydroxybenzoic, gallic, vanillic, syringic, and ferulic acids...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930269/chemical-composition-antifungal-and-antioxidant-activities-of-hedyosmum-brasiliense-mart-ex-miq-chloranthaceae-essential-oils
#11
Cynthia Murakami, Inês Cordeiro, Marcus Tullius Scotti, Paulo Roberto H Moreno, Maria Cláudia M Young
Background: Hedyosmum brasiliense Mart. ex Miq. (Chloranthaceae) is a dioecious shrub popularly used in Brazil to treat foot fungi and rheumatism. This work investigated the chemical composition, antifungal, and antioxidant activities of flowers and leaves of H. brasiliense essential oils; Methods: H. brasiliense male and female flowers and leaves were collected at Ilha do Cardoso (São Paulo) and the essential oils were extracted by hydrodistillation and analyzed by GC/MS and their similarity compared by Principal Component Analysis...
July 17, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930251/chemical-profiling-and-evaluation-of-antioxidant-and-anti-microbial-properties-of-selected-commercial-essential-oils-a-comparative-study
#12
Ângelo Luís, Ana Paula Duarte, Luísa Pereira, Fernanda Domingues
Background: The last decades have seen an increased awareness by the scientific community of the extent of resistance to conventional antibiotics, particularly with respect to the emerging multidrug-resistant pathogenic microbes. Additionally, natural antioxidants have received significant attention among food professionals and consumers because of their assumed safety and potential therapeutic value. The aim of this work was to assess the antioxidant activities of eight selected commercial essential oils (EOs), together with the evaluation of their antibacterial and anti-quorum sensing properties...
June 5, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930244/characterization-and-antioxidant-activity-of-volatile-constituents-from-different-parts-of-aframomum-danielli-hook-k-schum
#13
Emmanuel E Essien, Paul S Thomas, Kelly Oriakhi, Mohammad I Choudhary
Background:Aframomum danielli is used in ethno-medicine for the treatment of several ailments and as a traditional food spice. Methods: The hydro-distilled leaf, stem, seed, rhizome and pod volatile oils of A. danielli were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. Results: Thirty-nine (39) volatile compounds were identified in the oils of A...
May 10, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930239/eryngium-foetidum-l-essential-oils-chemical-composition-and-antioxidant-capacity
#14
Paul S Thomas, Emmanuel E Essien, Samuel J Ntuk, Mohammad I Choudhary
Background:Eryngium foetidum essential oils from Nigeria were investigated for the first time in order to ascertain their potency as natural antioxidants. E. foetidum is an aromatic and medicinal herb used in ethno-medicine and as a traditional spice for foods. Methods: The hydro-distilled oils of E. foetidum were subjected to gas chromatography-mass spectrometry (GC-MS) analysis. Free radical scavenging capacity of the volatile oils was determined using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays...
April 28, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28930232/antimicrobial-antioxidant-and-cytotoxic-activities-of-ocimum-forskolei-and-teucrium-yemense-lamiaceae-essential-oils
#15
Nasser A Awadh Ali, Bhuwan K Chhetri, Noura S Dosoky, Khola Shari, Ahmed J A Al-Fahad, Ludger Wessjohann, William N Setzer
Background:Ocimum forskolei and Teucrium yemense (Lamiaceae) are used in traditional medicine in Yemen. Methods: The chemical composition, antimicrobial, antioxidant and cytotoxic activities of the essential oils isolated from the leaves of Ocimum forskolei Benth. (EOOF) and two different populations of Teucrium yemense Deflers., one collected from Dhamar province (EOTY-d), and another collected from Taiz (EOTY-t) were investigated. The antimicrobial activities of the oils were evaluated against several microorganisms with the disc diffusion test or the broth microdilution test...
April 1, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929917/mercurius-solubilis-attenuates-scopolamine-induced-memory-deficits-and-enhances-the-motor-coordination-in-mice
#16
Simranjeet Kaur, Anudeep Kaur, Gurjit Singh, Rajbir Bhatti
The present study was designed to investigate the effect of mercurius solubilis (Merc sol) on scopolamine induced memory deficits and motor coordination in mice. The Three different formulations of merc sol (30X, 200 M, 1 M) were screened for their in vitro antioxidant potential and DPPH (2, 2-diphenyl-1-picrylhydrazyl) and nitric oxide scavenging activity using response surface methodology. The Merc sol 30X formulation was found to be most potent and further subjected for in vivo experiment. The Memory impairment was induced by the administration of scopolamine (1 mg/kg i...
September 20, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28928864/high-immunoreactivity-of-duox2-is-associated-with-poor-response-to-preoperative-chemoradiation-therapy-and-worse-prognosis-in-rectal-cancers
#17
Shih-Chun Lin, I-Wei Chang, Pei-Ling Hsieh, Ching-Yih Lin, Ding-Ping Sun, Ming-Jen Sheu, Ching-Chieh Yang, Li-Ching Lin, Hong-Lin He, Yu-Feng Tian
Purpose: Colorectal cancer is the third most common cancer and also the fourth most common cause of cancer mortality worldwide. For rectal cancer, neoadjuvant concurrent chemoradiotherapy (CCRT) followed by radical proctectomy is gold standard treatment for patients with stage II/III rectal cancer. By data mining a documented database of rectal cancer transcriptome (GSE35452) from Gene Expression Omnibus, National Center of Biotechnology Information, we recognized that DUOX2 was the most significantly up-regulated transcript among those related to cytokine and chemokine mediated signaling pathway (GO:0019221)...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28928529/antioxidant-properties-and-phenolic-profile-characterization-by-lc-ms-ms-of-selected-tunisian-pomegranate-peels
#18
Mouna Abid, Héla Yaich, Salma Cheikhrouhou, Ibtihel Khemakhem, Mohamed Bouaziz, Hamadi Attia, M A Ayadi
Antioxidant contents and activities of different extracts from four Tunisian pomegranate peels, locally called "Acide", "Gabsi", "Nebli" and "Tounsi", were studied. Peels samples were extracted with three solvents (water, ethanol and acetone). For each extract, the total phenol contents and antioxidant activity were evaluated. The highest values of polyphenol, tannins, flavonoids and anthocyanins were recorded in the acetone extract of Acide ecotype with 304.6 mg gallic acid equivalent/g; 292.23 mg gallic acid equivalent/g; 15...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28928512/determination-of-antioxidant-activity-of-hibiscus-sabdariffa-and-croton-caudatus-in-saccharomyces-cerevisiae-model-system
#19
Pattnaik Subhaswaraj, M Sowmya, V Bhavana, Madhu Dyavaiah, Busi Siddhardha
From ancient times, plants and plant derived products are exploited as a prominent source of folkloric medicines with tremendous therapeutic potential for an array of health disorders. In the present study, ethanolic leaf extract of Hibiscus sabdariffa and Croton caudatus were evaluated for free radical scavenging activity in Saccharomyces cerevisiae model system. H. sabdariffa and C. caudatus showed tremendous DPPH free radical scavenging potential with an IC50 value of 184.88 and 305.39 µg/mL respectively at a concentration of 500 µg/mL...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28928445/phase-retrieved-tomography-enables-mesoscopic-imaging-of-opaque-tumor-spheroids
#20
Daniele Ancora, Diego Di Battista, Georgia Giasafaki, Stylianos E Psycharakis, Evangelos Liapis, Jorge Ripoll, Giannis Zacharakis
We present a new Phase-Retrieved Tomography (PRT) method to radically improve mesoscopic imaging at regimes beyond one transport mean-free-path and achieve high resolution, uniformly throughout the volume of opaque samples. The method exploits multi-view acquisition in a hybrid Selective Plane Illumination Microscope (SPIM) and Optical Projection Tomography (OPT) setup and a three-dimensional Gerchberg-Saxton phase-retrieval algorithm applied in 3D through the autocorrelation sinogram. We have successfully applied this innovative protocol to image optically dense 3D cell cultures in the form of tumor spheroids, highly versatile models to study cancer behavior and response to chemotherapy...
September 19, 2017: Scientific Reports
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