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L Castilla-Guerra, M C Fernandez-Moreno, S Vergara-Lopez, M Merino-Rumin, M A Colmenero-Camacho
INTRODUCTION: Tick-borne relapsing fever (TBRF) can cause neurological complications. There are hardly any studies in Spain on this subject. AIM: To study the prevalence and clinical characteristics of neurological complications of patients with TBRF. PATIENTS AND METHODS: We retrospectively reviewed all the patients attended with TBRF over 12 years (2004-2015) in a hospital in a rural area of southern Spain. RESULTS: We included 75 patients, 42 males (56%)...
September 16, 2016: Revista de Neurologia
Admasu Tenna Mamuye, Ethan Bornstein, Obsie Temesgen, Henry M Blumberg, Russell R Kempker
In a cross-sectional study among hospitalized human immunodeficiency virus (HIV)-infected patients in Ethiopia, we sought to determine the rates and predictors of cryptococcal disease and evaluate the test performance of a recently introduced point-of-care test for Cryptococcus neoformans detection in various biological samples. We tested serum, urine, and fingerstick blood samples from each patient with a cryptococcal antigen lateral flow assay (CRAG LFA; Immuno Mycologic Inc., Norman, OK). Cerebrospinal fluid was collected at the discretion of the treating physician...
October 5, 2016: American Journal of Tropical Medicine and Hygiene
A Kamawal, M A Schmidt, O Rompel, G C Gusek-Schneider, C Y Mardin, R Trollmann
Complications of acute bacterial sinusitis mostly occur in children and adolescents. In particular, intracranial spread of the infection can lead to severe even fatal courses of the disease. This article is a case report about a 13-year-old boy suffering from left-sided headache, meningismus and exophthalmos as presenting symptoms. Cranial magnetic resonance imaging (MRI) showed merely right-sided sphenoid sinusitis; however, the diffusion-weighted MRI sequence indicated a left-sided cavernous sinus thrombosis, which could be confirmed by computed tomography (CT) angiography...
July 11, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Aakash Kaushik Shah, Andrey Bilko, James Kimo Takayesu
BACKGROUND: Epidural steroid injections are frequently used to treat back and extremity pain. The procedure is generally safe, with a low rate of adverse events, including intrathecal entry, pneumocephalus, and chemical meningitis. CASE REPORT: We report a case of a 45-year-old woman who presented to the emergency department (ED) with headache, nausea, vomiting, and photophobia after a lumbar epidural steroid injection. She was afebrile and had an elevated white blood cell count...
September 2016: Journal of Emergency Medicine
Anil V Israni, Divya A Dave, Anirban Mandal, Amitabh Singh, Puneet K Sahi, Rashmi Ranjan Das, Arpita Shah
CONTEXT: Childhood tuberculosis is a major public health problem in developing countries with tubercular meningitis being a serious complication with high mortality and morbidity. AIM: To study the clinicopathological as well as radiological profile of childhood tuberculous meningitis (TBM) cases. SETTINGS AND DESIGN: Prospective, observational study including children <14 years of age with TBM admitted in a tertiary care hospital from Western India...
July 2016: Journal of Neurosciences in Rural Practice
Ghazala A Datoo O'Keefe, Narsing A Rao
Vogt-Koyanagi-Harada disease, a severe bilateral granulomatous intraocular inflammation associated with serous retinal detachments, disk edema, and vitritis, with eventual development of a sunset glow fundus, is an autoimmune inflammatory condition mediated by T cells that target melanocytes in individuals susceptible to the disease. Vogt-Koyanagi-Harada disease presents clinically in 4 different phases: prodromal, uveitic, convalescent, and recurrent, with extraocular manifestations including headache, meningismus, hearing loss, poliosis, and vitiligo, to varying degrees...
May 27, 2016: Survey of Ophthalmology
Saad Akhtar, Abdul Azeem, Amyna Jiwani, Gohar Javed
INTRODUCTION: There are variations in the anatomy of the vertebrobasilar system amongst which the Anterior Inferior Cerebellar Artery-Posterior Inferior Cerebellar Artery (AICA-PICA) variant is thought to have a prevalence of 20-24% (based on retrospective studies). Despite this, aneurysms of the AICA-PICA variant are rare. We present a case of an AICA-PICA aneurysm and discuss its presentation and management, along with a review of literature. PRESENTATION OF CASE: We describe the case of a 35 year old female who presented with signs of meningismus...
2016: International Journal of Surgery Case Reports
Pamela Talley, Stacy Holzbauer, Kirk Smith, William Pomputius
On April 20, 2015, a female aged 15 years sought care at her pediatrician's office after 5 days of fever, myalgia, left parietal headache, and photophobia. A rapid influenza assay was negative, and erythrocyte sedimentation rate and total white blood cell count were normal. She improved with symptomatic care at home, but returned to her pediatrician's office on April 28, reporting recurrence of her headache and photophobia and new onset of a stiff neck. She was admitted to the hospital, where she was febrile to 102...
March 11, 2016: MMWR. Morbidity and Mortality Weekly Report
Armond S Goldman, Elisabeth J Schmalstieg, Charles F Dreyer, Frank C Schmalstieg, Daniel A Goldman
In 2003, we published evidence that the most likely cause of FDR's 1921 neurological disease was Guillain-Barré syndrome. Afterwards, several historians and neurologists stated in their publications that FDR had paralytic poliomyelitis. However, significant criticism of our article or new support for that diagnosis was not revealed. One critic claimed that FDR's cerebrospinal fluid indicated poliomyelitis, but we did not find evidence that a lumbar puncture was performed. The diagnosis of FDR's neurological disease still depends upon documented clinical abnormalities...
October 27, 2015: Journal of Medical Biography
Mehrdad Hosseinzadeh Bakhtevari, Guive Sharifi, Reza Jabbari, Misagh Shafizad, Mona Rezaei, Mohammad Samadian, Omidvar Rezaei
BACKGROUND: Colloid cysts are benign third ventricle lesions that need to be diagnosed correctly because of their association with sudden death. Chemical or aseptic meningitis is a rare presentation of a colloid cyst. METHODS: We present a case of a 69-year-old man with fever, alteration of mental status, and meningismus. Microbiological examination of the cerebrospinal fluid revealed aseptic meningitis. Brain imaging revealed a third ventricular colloid cyst with hydrocephalus...
December 2015: World Neurosurgery
Serhan Derin, Murat Sahan, Derya Burcu Hazer, Leyla Sahan
Paranasal sinus infections are very common. Dental infections, tumours and anatomical malformations can cause unilateral sinusitis. Most cases can be treated without complications. However, rare life-threatening intracranial complications can occur. Generally, an intracranial complication progresses rapidly and can cause meningismus, focal neurological disorders, loss of consciousness and seizures. In such cases, an emergency craniotomy and concurrent sinus surgery are required. This article presents a 16-year-old patient with pansinusitis and subdural empyema that developed after a dental abscess...
2015: BMJ Case Reports
Rasim Babayev, Murat Şakir Ekşi
Spinal epidural hematoma is a rare neurosurgical emergency in respect of motor and sensory loss. Identifiable reasons for spontaneous hemorrhage are vascular malformations and hemophilias. We presented a case of spontaneous epidural hematoma in an 18-year-old female patient who had motor and sensory deficits that had been present for 1 day. On MRI, there was spinal epidural hematoma posterior to the T2-T3 spinal cord. The hematoma was evacuated with T2 hemilaminectomy and T3 laminectomy. Patient recovered immediately after the surgery...
January 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Jayesh P Thawani, Nikhil R Nayak, Jared M Pisapia, Dmitriy Petrov, Bryan A Pukenas, Robert W Hurst, Michelle J Smith
BACKGROUND: Intracranial vasculopathy in adult patients with human-acquired immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is a rare but increasingly recognized disease entity. OBJECTIVE: We aimed to contribute to and summarize the adult literature describing patients with HIV/AIDS who have intracranial vasculopathy. METHODS: A retrospective review of adult patients with HIV/AIDS undergoing diagnostic cerebral angiography at our institution from 2007-2013 was performed...
August 2015: Interventional Neuroradiology
Kevin T Huang, Wenya Linda Bi, Timothy R Smith, Amir A Zamani, Ian F Dunn, Edward R Laws
PURPOSE: Intrasellar abscess is an uncommon cause of mass lesions in the sella turcica. Few cases have been reported in the literature, and much remains unknown about the etiology and diagnosis of these lesions. We sought to review a series of patients with intrasellar abscess encountered at our institution and identify defining characteristics of their presentation and management. METHODS: We conducted a retrospective chart review for intrasellar infection cases associated with a mass lesion...
October 2015: Pituitary
Praveen Ganesh, Muralidhara Nagarjuna, Samarth Shetty, Pradeep Kumar, Venkatraman Bhat, Paul C Salins
Fungi are ubiquitous in nature but have low virulence and cause disease usually when the host defenses are compromised. Fungal infections of the central nervous system are rare and are usually seen in immunocompromised patients. However, in recent years, there has been an increase in the number of central nervous system fungal infections in immunocompetent individuals. Intracranial fungal granulomas are rare space-occupying lesions. Among these, Aspergillus granuloma is the most common. Craniocerebral involvement by aspergillosis usually occurs via the hematogenous route or through contiguous spread from the paranasal sinuses...
February 2015: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Laxmi P Dhakal, David O Hodge, Jay Nagel, Michael Mayes, Alexa Richie, Lauren K Ng, William D Freeman
No abstract text is available yet for this article.
June 2015: Neurocritical Care
Laxmi P Dhakal, David O Hodge, Jay Nagel, Jay Nagal, Michael Mayes, Alexa Richie, Lauren K Ng, William D Freeman
BACKGROUND: Headache after aneurysmal subarachnoid hemorrhage (SAH) is very common and is often described as the "worst headache imaginable." SAH-associated headache can persist for days to weeks and is traditionally treated with narcotics. However, narcotics can have significant adverse effects. We hypothesize that gabapentin (GBP), a non-narcotic neuropathic pain medication, would be safe and tolerable and would reduce narcotic requirements after SAH. METHODS: We retrospectively reviewed the clinical, radiographic, and laboratory data of SAH patients at the neuroscience intensive care unit at Mayo Clinic in Jacksonville, Florida, from January 2011 through February 2013...
June 2015: Neurocritical Care
Ashley N Wilking, Elizabeth Elliott, Melissa N Garcia, Kristy O Murray, Flor M Munoz
BACKGROUND: A novel H1N1 influenza A virus (A(H1N1)pdm09) particularly affected individuals <24 years of age during the 2009 pandemic. This study sought to better understand the risks and outcomes of central nervous system complications associated with pandemic influenza in the pediatric population. METHODS: Retrospective review of patients with laboratory-confirmed influenza A(H1N1)pdm09 infection and central nervous system manifestations at Texas Children's Hospital between April 2009 and June 2010...
September 2014: Pediatric Neurology
Pradeep A V, Arun Kumar J S, Naveen K N, Sonali Rao, Sharan Shetty
Vogt-Koyanagi-Harada syndrome (VKH) is a bilateral intraocular granulomatous panuveitis which is frequently associated with systemic manifestations such as meningismus, tinnitus, poliosis and vitiligo of autoimmune aetiology. Headache by itself, does not fulfill the diagnostic criteria and is insufficient for the diagnosis. A 22-year-old male presented with a 10 day history of headache, followed by decreased vision in both eyes. Slit lamp biomicroscopy revealed sluggishly reactive pupils with anterior uveitis, mild vitritis and hyperaemic discs with bilateral exudative retinal detachments...
April 2014: Journal of Clinical and Diagnostic Research: JCDR
Raffaella Vergaro, Duccio Maria Cordelli, Angela Miniaci, Davide Tassinari, Luca Spinardi, Andrea Pession, Emilio Franzoni
BACKGROUND: Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disorder characterized by ocular, auditory and neurological manifestations (headache, meningismus and/or aspeptic meningoencephalitis). PATIENT: We describe a 12-year-old African boy with bilateral uveitis who presented with acute unilateral hearing loss and neurological symptoms such as left-sided dyskinesias, unsteady gait and throbbing headache. Brain magnetic resonance imaging showed ischemic lesions of the right basal ganglia in the territory of lenticulostriate and thalamic arteries...
July 2014: Pediatric Neurology
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