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https://www.readbyqxmd.com/read/27915128/cholesterol-reducing-agents-inhibit-assembly-of-type-i-parainfluenza-viruses
#1
Shringkhala Bajimaya, Tsuyoshi Hayashi, Tünde Frankl, Peter Bryk, Brian Ward, Toru Takimoto
Many enveloped RNA viruses utilize lipid rafts for the assembly of progeny virions, but the role of cholesterol, a major component of rafts, on paramyxovirus budding and virion formation is controversial. In this study, we analyzed the effects of FDA-approved cholesterol-reducing agents, gemfibrozil and lovastatin, on raft formation and assembly of human parainfluenza virus type 1 (hPIV1) and Sendai virus (SeV). Treatment of the human airway epithelial A549 cells with the agents, especially when combined, significantly decreased production of infectious hPIV1 and SeV...
December 1, 2016: Virology
https://www.readbyqxmd.com/read/27903837/the-effect-of-army-vest-design-on-the-occurrence-of-stress-fractures-and-overuse-injuries-in-female-military-recruits
#2
Ezequiel Palmanovich, M Frankl, M Nyska, I Hetsroni, N Constantini, L Trejo, R Bechar, G Novak, Z Lankovsky, G Mann
INTRODUCTION: Stress fractures (SFs) occur when microdamage caused by repetitive mechanical load exceeds the biological load-bearing capacity of the bone. The study objective was to test whether a vest specifically designed and manufactured for female recruits, compared with the standard vest used on a regular basis by Border Police recruits, would reduce the incidence of SF in female Border Police recruits. Data based on reports of military personnel show that women are more likely to sustain SFs...
November 30, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27868388/in-vitro-lipolysis-is-associated-with-whole-body-lipid-oxidation-and-weight-gain-in-humans
#3
Joseph Frankl, Paolo Piaggi, James E Foley, Jonathan Krakoff, Susanne B Votruba
OBJECTIVE: To assess the association of adipocyte size with cellular lipolysis and between cellular lipolysis and whole-body lipid oxidation. This study also assessed the association between adipocyte size and cellular lipolysis with weight and fat mass gain. METHODS: Subjects had assessment of percent body fat (%fat) and adipose tissue biopsy for in vitro lipolysis (n = 325), and a subset of subjects had measurement of whole-body lipid oxidation (n = 112). A subset of subjects (n = 243) returned for repeated measurements of body weight and composition (mean follow-up 8...
November 21, 2016: Obesity
https://www.readbyqxmd.com/read/27795998/a-classification-system-for-the-spread-of-polymethyl-methacrylate-in-vertebral-bodies-treated-with-vertebral-augmentation
#4
Joseph Frankl, Michael P Sakata, Gagandeep Choudhary, Seung Hur, Andrew Peterson, Charles T Hennemeyer
In this study, we develop a classification system for describing polymethyl methacrylate (PMMA) spread in vertebral bodies after kyphoplasty or vertebroplasty for vertebral compression fractures (VCFs) and for assessing whether PMMA spread varies between operators, VCF etiology, or vertebral level. Intraoperative fluoroscopic images of 198 vertebral levels were reviewed in 137 patients (women, 84; men, 53; mean age, 75.8 ± 12.5; and those with a diagnosis of osteoporosis, 63%) treated with kyphoplasty between January 01, 2015 and May 31, 2015 at a single center to create a 5-class descriptive system...
September 2016: Tomography: a Journal for Imaging Research
https://www.readbyqxmd.com/read/27759415/which-maternal-personality-traits-affect-child-behaviour-during-dental-treatment
#5
A H Arpaci, B Işik, N Cura, B Kaplan, P Bozkurt
AIM: Maternal personality traits affect child dental behaviour and have a potential link with dental treatment methods. This study aims to evaluate which maternal personality traits affect child dental behaviour. MATERIALS AND METHODS: Research was carried out upon 60 children aged between 3-12 years, who had been admitted to our clinic for tooth extraction. All children were evaluated by means of the Frankl Behavior Scale (FBS): degrees I and II represent negative behaviours, while III and IV positive behaviour...
September 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27729085/chordoma-dedifferentiation-after-proton-beam-therapy-a-case-report-and-review-of-the-literature
#6
Joseph Frankl, Cassi Grotepas, Baldassare Stea, G Michael Lemole, Alexander Chiu, Rihan Khan
BACKGROUND: Chordoma is a rare invasive bone tumor that may occur anywhere along the neuraxis. A total of three primary histological varieties have been identified: conventional, chondroid, and dedifferentiated. CASE PRESENTATION: We report a case of an 8-year-old white girl who presented with conventional chordoma, was treated with surgical resection and mixed proton and photon beam therapy, and had a recurrence in the resection cavity 2.5 years later with dedifferentiated morphology...
October 12, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27637195/-the-problem-of-beginning-of-the-personal-being-in-the-anthropology-of-v-e-frankl
#7
Juan Fernando Sellés Dauder
In this paper we review the V. E. Frankl' conception of the 'person', which he understands as the superior part in man. This study consists of three parts: a) In the first we study 10 thesis that the father of logotherapy offers on the person, namely: 1st) the person is an individual; 2nd) whitaut possibility of sum; 3rd) is a new being; 4th) is spiritual; 5th) is existential; 6th) is the 'I' or the 'ego'; 7th) provides unity and wholeness; 8th) is dynamic; 9th) is able to transcend and to face herself; 10th) He is not understood by itself but from the point of view of transcendence...
May 2016: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/27624646/kanner-asperger-and-frankl-a-third-man-at-the-genesis-of-the-autism-diagnosis
#8
John E Robison
Scholars have long speculated about how Kanner and Asperger's descriptions of autistic behavior appeared just 1 year apart in America and Austria even as World War II had severed communication between the two countries. Both conspiracy and serendipity have been alleged, but a simpler explanation has now emerged. Autistic knowledge crossed the Atlantic with Georg Frankl-a previously unrecognized "man in the middle" who followed his fiancé to America. The evidence presented here fills in many blanks and suggests both Kanner and Asperger benefited from Frankl's insight...
September 13, 2016: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/27608043/antibiotic-treatment-in-end-of-life-cancer-patients-a-retrospective-observational-study-at-a-palliative-care-center-in-sweden
#9
Maria Helde-Frankling, Jenny Bergqvist, Peter Bergman, Linda Björkhem-Bergman
BACKGROUND: The aim of this study was to elucidate whether palliative cancer patients benefit from antibiotic treatment in the last two weeks of life when an infection is suspected. METHOD: We reviewed medical records from 160 deceased palliative cancer patients that had been included in previous studies on vitamin D and infections. Patients treated with antibiotics during the last two weeks of life were identified and net effects of treatment (symptom relief) and possible adverse events were extracted from medical records...
September 6, 2016: Cancers
https://www.readbyqxmd.com/read/27583111/morphologic-variability-of-the-shoulder-between-the-populations-of-north-american-and-east-asian
#10
Andres F Cabezas, Kristi Krebes, Michael M Hussey, Brandon G Santoni, Hyuong Sik Kim, Mark A Frankle, Joo Han Oh
BACKGROUND: The aim of this study was to determine if there were significant differences in glenohumeral joint morphology between North American and East Asian populations that may influence sizing and selection of shoulder arthroplasty systems. METHODS: Computed tomography reconstructions of 92 North American and 58 East Asian patients were used to perform 3-dimensional measurements. The proximal humeral position was normalized in all patients by aligning it with the scapular plane utilizing anatomic landmarks...
September 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27556551/evaluation-of-children-s-dental-anxiety-levels-at-a-kindergarten-and-at-a-dental-clinic
#11
Gulser Kilinç, Aynur Akay, Ece Eden, Nilgün Sevinç, Hülya Ellidokuz
This study evaluated the dental anxiety levels of preschool children at a kindergarten and at a dental clinic. The anxiety levels of ninety 4-6-year-old (4.99 ± 0.81) preschool children were evaluated according to pulse rates, the facial image scale (FIS), the Venham picture test (VPT), and the Frankl behavior rating scale. The children's mothers were asked to complete the state-trait anxiety inventory (STAI) forms 1 and 2 (STAI 2 and STAI 2). The sample t-test, Mann-Whitney U test, and Pearson's correlation test were used...
August 18, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27544989/-clinical-and-arthroscopic-findings-in-meniscal-injury-and-knee-instability-a-prospective-study
#12
Ezequiel Palmanovich, Amir Manor, Iftach Hetsroni, Niv Marom, Alexander Finsterbush, Uri Frankl, Joseph Lowe, Gideon Mann
INTRODUCTION: Medical history and physical examination are expected to provide the basic knowledge allowing diagnosis of a disease and thus enabling to plan the course of treatment. OBJECTIVE: This study aimed to examine this hypothesis by comparing pre-operative diagnosis of meniscal and anterior cruciate ligament (ACL) injuries to final surgical findings. MATERIAL AND METHODS: We prospectively compared the pre-surgical diagnosis to the arthroscopic findings in 753 arthroscopic procedures...
June 2016: Harefuah
https://www.readbyqxmd.com/read/27544988/-a-novel-gender-specific-vest-for-female-infantry-recruits-does-not-reduce-the-incidence-of-overuse-pain-syndromes-a-prospective-randomized-study-among-240-recruits
#13
RANDOMIZED CONTROLLED TRIAL
Ezequiel Palmanovich, Michal Frankl, Iftach Hetsroni, Meir Nyska, Niv Maron, Naama Constantin, Leonardo Trejo, Ron Bechar, Gideon Novak, Zeev Lankovsky, Gideon Mann
INTRODUCTION: Overuse pain syndromes constitute a troublesome byproduct of military infantry training, particularly in female fighters. These injuries result in lost days of training, pain and discomfort and can affect fitness and fighting abilities. We hypothesized that a gender specific vest would reduce the incidence of overuse pain syndromes in a population of female recruits during basic training. OBJECTIVE: The purpose of this study was therefore to examine the effect of a novel gender-specific combat vest on the incidence of lower back pain (LBP), anterior knee pain syndrome (AKPS), and plantar heel foot pain (PHFP) among female recruits...
June 2016: Harefuah
https://www.readbyqxmd.com/read/27543521/i-spy-with-my-little-eye-something-beginning-with-s-spotting-sepsis
#14
EDITORIAL
C C Frankling, J Yeung, P Dark, F Gao
No abstract text is available yet for this article.
September 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/27528702/to-be-or-not-to-be%C3%A2
#15
EDITORIAL
Fiona E Karet Frankl
No abstract text is available yet for this article.
October 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27525135/budd-chiari-syndrome-in-a-patient-with-hepatitis-c
#16
Joseph Frankl, Charles Hennemeyer, Michael S Flores, Archita P Desai
Chronic Budd-Chiari syndrome can present with cirrhosis and signs and symptoms similar to those of other chronic liver diseases. We present a case of Budd-Chiari syndrome discovered during attempted transjugular intrahepatic portosystemic shunting in a patient with decompensated cirrhosis believed to be secondary to hepatitis C. Although the patient had hepatocellular carcinoma, the Budd-Chiari syndrome was a primary disease due to hepatic venous webs. Angioplasty was performed in this case, which resolved the patient's symptoms related to portal hypertension...
2016: Case Reports in Hepatology
https://www.readbyqxmd.com/read/27511788/the-importance-of-being-rare
#17
COMMENT
Fiona E Karet Frankl
No abstract text is available yet for this article.
August 6, 2016: Lancet
https://www.readbyqxmd.com/read/27461917/psychometric-properties-of-the-affect-phobia-test
#18
My Frankl, Björn Philips, Lene Berggraf, Pål Ulvenes, Robert Johansson, Peter Wennberg
The aim of this study was to make the first evaluation of the psychometric properties of the Affect Phobia Test, using the Swedish translation - a test developed to screen the ability to experience, express and regulate emotions. Data was collected from a clinical sample (N = 82) of patients with depression and/or anxiety participating in randomized controlled trial of Internet-based affect-focused treatment, and a university student sample (N = 197). The internal consistency for the total score was satisfactory (Clinical sample α = 0...
October 2016: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/27415445/blueprint-for-an-undergraduate-primary-care-curriculum
#19
Sara B Fazio, Monica Demasi, Erin Farren, Susan Frankl, Barbara Gottlieb, Jessica Hoy, Amanda Johnson, Jill Kasper, Patrick Lee, Claire McCarthy, Kathe Miller, Juliana Morris, Kitty O'Hare, Rachael Rosales, Leigh Simmons, Benjamin Smith, Katherine Treadway, Kristen Goodell, Barbara Ogur
In light of the increasing demand for primary care services and the changing scope of health care, it is important to consider how the principles of primary care are taught in medical school. While the majority of schools have increased students' exposure to primary care, they have not developed a standardized primary care curriculum for undergraduate medical education. In 2013, the authors convened a group of educators from primary care internal medicine, pediatrics, family medicine, and medicine-pediatrics, as well as five medical students to create a blueprint for a primary care curriculum that could be integrated into a longitudinal primary care experience spanning undergraduate medical education and delivered to all students regardless of their eventual career choice...
July 12, 2016: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/27399528/330%C3%A2-outcome-of-percutaneous-versus-open-posterior-spinal-fixation-in-thoracolumbar-fractures
#20
Ahmed Mohamed Elsawaf
INTRODUCTION: Unstable thoracolumbar fractures are usually managed by posterior instrumentation. The standard open pedicle screw fixation or the newly introduced percutaneous technique can be used. The purpose of this study is to provide safety and feasibility of both techniques and getting a more obvious plan for choosing either of them in such cases. METHODS: In a prospective study of a total of 166 patients with unstable thoracolumbar fractures with a mean follow-up of 14 months (range 10-21), the patients were classified randomly into 2 groups: Group I: patients who underwent percutaneous spinal fixation and minimally invasive decompression if needed (72 patients)...
August 2016: Neurosurgery
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