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https://www.readbyqxmd.com/read/28099588/dobutamine-stress-echocardiography-safety-in-chagas-disease-patients
#1
Daniela do Carmo Rassi, Marcelo Luiz Campos Vieira, Rogerio Gomes Furtado, Fabio de Paula Turco, Luciano Henrique Melato, Viviane Tiemi Hotta, Colandy Godoy de Oliveira Nunes, Luiz Rassi, Salvador Rassi
Background: A few decades ago, patients with Chagas disease were predominantly rural workers, with a low risk profile for obstructive coronary artery disease (CAD). As urbanization has increased, they became exposed to the same risk factors for CAD of uninfected individuals. Dobutamine stress echocardiography (DSE) has proven to be an important tool in CAD diagnosis. Despite being a potentially arrhythmogenic method, it is safe for coronary patients without Chagas disease. For Chagas disease patients, however, the indication of DSE in clinical practice is uncertain, because of the arrhythmogenic potential of that heart disease...
January 16, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28099587/non-invasive-ventilation-in-patients-with-heart-failure-a-systematic-review-and-meta-analysis
#2
Hugo Souza Bittencourt, Helena França Correia Dos Reis, Melissa Santos Lima, Mansueto Gomes
Non-invasive ventilation (NIV) may perfect respiratory and cardiac performance in patients with heart failure (HF). The objective of the study to establish, through systematic review and meta-analysis, NIV influence on functional capacity of HF patients. A systematic review with meta-analysis of randomized studies was carried out through research of databases of Cochrane Library, SciELO, Pubmed and PEDro, using the key-words: heart failure, non-invasive ventilation, exercise tolerance; and the free terms: bi-level positive airway pressure (BIPAP), continuous positive airway pressure (CPAP), and functional capacity (terms were searched for in English and Portuguese) using the Boolean operators AND and OR...
January 16, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28099586/serotoninergic-modulation-of-basal-cardiovascular-responses-and-responses-induced-by-isotonic-extracellular-volume-expansion-in-rats
#3
Isadora Ferraz Semionatto, Adrieli Oliveira Raminelli, Angelica Cristina Alves, Caroline Santos Capitelli, Rosangela Soares Chriguer
Background: Isotonic blood volume expansion (BVE) induced alterations of sympathetic and parasympathetic activity in the heart and blood vessels, which can be modulated by serotonergic pathways. Objective: To evaluate the effect of saline or serotonergic agonist (DOI) administration in the hypothalamic paraventricular nucleus (PVN) on cardiovascular responses after BVE. Methods: We recorded pulsatile blood pressure through the femoral artery to obtain the mean arterial pressure (MAP), systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR) and the sympathetic-vagal ratio (LF/HF) of Wistar rats before and after they received bilateral microinjections of saline or DOI into the PVN, followed by BVE...
January 16, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28032880/hepatitis-isqu%C3%A3-mica-secundaria-a-taponamiento-cardiaco-una-causa-poco-frecuente
#4
S Goñi Esarte, J M Zozaya Urmeneta, M Goñi Esarte, J I Uriz Otano, I Idoate Santesteban, M T Beunza Puyol
La hepatitis isquémica es una entidad poco frecuente. Se asocia a una hipoperfusión hepática debida en primer lugar a un bajo gasto cardíaco (insuficiencia cardiaca congestiva, infarto agudo de miocardio o miocardiopatía dilatada). De forma menos frecuente puede ser secundaria a una insuficiencia respiratoria o al aumento de las necesidades de oxígeno en el contexto de una sepsis.Paciente varón de 49 años que acude al servicio de Urgencias por disnea progresiva e hipotensión, objetivándose una importante elevación de transaminasas (aspartato aminotransferasa de 5...
December 30, 2016: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/28011188/mid-range-ejection-fraction-does-not-permit-risk-stratification-among-patients-hospitalized-for-heart-failure
#5
Inés Gómez-Otero, Andreu Ferrero-Gregori, Alfonso Varela Román, José Seijas Amigo, Domingo A Pascual-Figal, Juan Delgado Jiménez, Jesús Álvarez-García, Francisco Fernández-Avilés, Fernando Worner Diz, Luis Alonso-Pulpón, Juan Cinca, José Ramón Gónzalez-Juanatey
INTRODUCTION AND OBJECTIVES: European Society of Cardiology heart failure guidelines include a new patient category with mid-range (40%-49%) left ventricular ejection fraction (HFmrEF). HFmrEF patient characteristics and prognosis are poorly defined. The aim of this study was to analyze the HFmrEF category in a cohort of hospitalized heart failure patients (REDINSCOR II Registry). METHODS: A prospective observational study was conducted with 1420 patients classified according to ejection fraction as follows: HFrEF, < 40%; HFmrEF, 40%-49%; and HFpEF, ≥ 50%...
December 20, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27992035/speckle-tracking-and-transthyretin-amyloid-cardiomyopathy
#6
Alexandre Marins Rocha, Suzane Garcia Ferreira, Marcelo Souto Nacif, Mario Luiz Ribeiro, Marcos Raimundo Gomes de Freitas, Cláudio Tinoco Mesquita
Background: Amyloidosis is a disease caused by deposits of insoluble fibrils in extracellular spaces. The most common type of familial amyloidosis is mediated by mutation of transthyretin, especially Val30Met. Symptoms and ejection fraction decrease may occur in cardiac amyloidosis only in case of poor prognosis. Myocardial strain detected by two-dimensional speckle tracking echocardiography can indicate changes in myocardial function at early stages of the disease. Objective: To determine the accuracy of left ventricular longitudinal strain by two-dimensional speckle tracking echocardiography in patients with familial amyloidosis caused by Val30Met transthyretin mutation...
December 19, 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27982377/polypharmacy-and-polymorbidity-in-older-adults-in-brazil-a-public-health-challenge
#7
Luiz Roberto Ramos, Noemia Urruth Leão Tavares, Andréa Dâmaso Bertoldi, Mareni Rocha Farias, Maria Auxiliadora Oliveira, Vera Lucia Luiza, Tatiane da Silva Dal Pizzol, Paulo Sérgio Dourado Arrais, Sotero Serrate Mengue
OBJECTIVE: To analyze variations in the prevalence of chronic use of medicines by older adults in Brazil according to its possible association with the most prevalent chronic diseases and demographic and health factors, and to identify risk factors for polypharmacy. METHODS: A study based on data from the National Survey on Access, Use and Promotion of Rational Use of Medicines (PNAUM), a cross-sectional, population-based survey with probability sampling in Brazilian urban areas...
December 2016: Revista de Saúde Pública
https://www.readbyqxmd.com/read/27982306/epinephrine-in-cardiac-arrest-systematic-review-and-meta-analysis
#8
Ignacio Morales-Cané, María Del Rocío Valverde-León, María Aurora Rodríguez-Borrego
Objective: evaluate the effectiveness of epinephrine used during cardiac arrest and its effect on the survival rates and neurological condition. Method: systematic review of scientific literature with meta-analysis, using a random effects model. The following databases were used to research clinical trials and observational studies: Medline, Embase and Cochrane, from 2005 to 2015. Results: when the Return of Spontaneous Circulation (ROSC) with administration of epinephrine was compared with ROSC without administration, increased rates were found with administration (OR 2...
December 8, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27982271/cardiac-magnetic-resonance-verified-myocardial-fibrosis-in-chagas-disease-clinical-correlates-and-risk-stratification
#9
Marly Uellendahl, Maria Eduarda Menezes de Siqueira, Eveline Barros Calado, Roberto Kalil-Filho, Dário Sobral, Clébia Ribeiro, Wilson Oliveira, Silvia Martins, Jagat Narula, Carlos Eduardo Rochitte
Background: Chagas disease (CD) is an important cause of heart failure and mortality, mainly in Latin America. This study evaluated the morphological and functional characteristics of the heart as well the extent of myocardial fibrosis (MF) in patients with CD by cardiac magnetic resonance (CMR). The prognostic value of MF evaluated by myocardial-delayed enhancement (MDE) was compared with that via Rassi score. Methods: This study assessed 39 patients divided into 2 groups: 28 asymptomatic patients as indeterminate form group (IND); and symptomatic patients as Chagas Heart Disease (CHD) group...
November 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27982270/elevated-heart-rate-is-associated-with-cardiac-denervation-in-patients-with-heart-failure-a-123-iodine-mibg-myocardial-scintigraphy-study
#10
Aline Sterque Villacorta, Humberto Villacorta, Jenne Serrão de Souza, José Antônio Caldas Teixeira, Maria Clara S S S Muradas, Christiane Rodrigues Alves, Bernardo Campanário Precht, Pilar Porto, Letícia Ubaldo, Cláudio Tinoco Mesquita, Antônio Cláudio Lucas da Nóbrega
Background: In the Systolic Heart Failure Treatment With the If Inhibitor Ivabradine Trial (SHIFT), heart rate (HR) reduction with ivabradine was associated with improved survival and reduced hospitalizations in patients with heart failure (HF). The mechanisms by which elevated HR increases mortality are not fully understood. Objective: To assess the relationship of baseline HR with clinical, neurohormonal and cardiac sympathetic activity in patients with chronic HF and elevated HR...
November 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27982268/utility-of-ultraportable-echocardiography-in-the-preoperative-evaluation-of-noncardiac-surgery
#11
Jean Allan Costa, Maria Lucia Pereira Almeida, Tereza Cristina Duque Estrada, Guilherme Lobosco Werneck, Alexandre Marins Rocha, Maria Luiza Garcia Rosa, Mario Luiz Ribeiro, Claudio Tinoco Mesquita
Background: The ultraportable echocardiogram machine, with relevant portability and easiness in performing diagnoses, when in experienced hands, may contribute to the reliability of preoperative evaluation in noncardiac surgeries. Objectives: To assess cardiac function parameters in patients aged older than 60 years, candidates of elective noncardiac surgeries, classified as ASA1 or ASA 2 according to surgical risk. Methods: A total of 211 patients referred for elective surgeries, without suspicion of previous heart diseases, were included in the study...
November 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27982160/lifestyle-intervention-on-metabolic-syndrome-and-its-impact-on-quality-of-life-a-randomized-controlled-trial
#12
Patrícia Pozas Saboya, Luiz Carlos Bodanese, Paulo Roberto Zimmermann, Andreia da Silva Gustavo, Fabricio Edler Macagnan, Ana Pandolfo Feoli, Margareth da Silva Oliveira
Background: Lifestyle intervention programs can reduce the prevalence of metabolic syndrome (MetS) and, therefore, reduce the risk for cardiac disease, one of the main public health problems nowadays. Objective: The aim of this study was to compare the effects of three types of approach for lifestyle change programs in the reduction of metabolic parameters, and to identify its impact on the quality of life (QOL) of individuals with MetS. Methods: A randomized controlled trial included 72 individuals with MetS aged 30-59 years...
December 8, 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27974438/transcriptome-analysis-of-drosophila-melanogaster-third-instar-larval-ring-glands-points-to-novel-functions-and-uncovers-a-cytochrome-p450-required-for-development
#13
Danielle Christesen, Ying Ting Yang, Jason Somers, Charles Robin, Tamar Sztal, Phillip Batterham, Trent Perry
In Drosophila melanogaster larvae the ring gland is a control center that orchestrates major developmental transitions. It is a composite organ, consisting of the prothoracic gland, the corpus allatum and the corpora cardiaca, each of which synthesizes and secretes a different hormone. Until now, the ring gland's broader developmental roles beyond endocrine secretion have not been explored. RNA sequencing and analysis of a new transcriptome resource from D. melanogaster wandering third instar larval ring glands has provided a fascinating insight into the diversity of developmental signalling in this organ...
December 14, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/27878221/the-use-of-a-metronome-during-cardiopulmonary-resuscitation-in-the-emergency-room-of-a-university-hospital
#14
Renata Maria de Oliveira Botelho, Cássia Regina Vancini Campanharo, Maria Carolina Barbosa Teixeira Lopes, Meiry Fernanda Pinto Okuno, Aécio Flávio Teixeira de Góis, Ruth Ester Assayag Batista
Objective: to compare the rate of return of spontaneous circulation (ROSC) and death after cardiac arrest, with and without the use of a metronome during cardiopulmonary resuscitation (CPR). Method: case-control study nested in a cohort study including 285 adults who experienced cardiac arrest and received CPR in an emergency service. Data were collected using In-hospital Utstein Style. The control group (n=60) was selected by matching patients considering their neurological condition before cardiac arrest, the immediate cause, initial arrest rhythm, whether epinephrine was used, and the duration of CPR...
November 21, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27856540/european-heart-rhythm-association-ehra-consensus-document-on-the-management-of-supraventricular-arrhythmias-endorsed-by-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-and-sociedad-latinoamericana-de-estimulaci%C3%A3-n-cardiaca-y-electrofisiologia
#15
Demosthenes G Katritsis, Giuseppe Boriani, Francisco G Cosio, Gerhard Hindricks, Pierre Jaïs, Mark E Josephson, Roberto Keegan, Young-Hoon Kim, Bradley P Knight, Karl-Heinz Kuck, Deirdre A Lane, Gregory Y H Lip, Helena Malmborg, Hakan Oral, Carlo Pappone, Sakis Themistoclakis, Kathryn A Wood, Carina Blomström-Lundqvist, Bulent Gorenek, Nikolaos Dagres, Gheorge-Andrei Dan, Marc A Vos, Gulmira Kudaiberdieva, Harry Crijns, Kurt Roberts-Thomson, Yenn-Jiang Lin, Diego Vanegas, Walter Reyes Caorsi, Edmond Cronin, Jack Rickard
No abstract text is available yet for this article.
November 17, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/27856499/european-heart-rhythm-association-ehra-consensus-document-on-the-management-of-supraventricular-arrhythmias-endorsed-by-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-and-sociedad-latinoamericana-de-estimulaci%C3%A3-n-cardiaca-y-electrofisiologia
#16
Demosthenes G Katritsis, Giuseppe Boriani, Francisco G Cosio, Gerhard Hindricks, Pierre Jais, Mark E Josephson, Roberto Keegan, Young-Hoon Kim, Bradley P Knight, Karl-Heinz Kuck, Deirdre A Lane, Gregory Y H Lip, Helena Malmborg, Hakan Oral, Carlo Pappone, Sakis Themistoclakis, Kathryn A Wood, Carina Blomström-Lundqvist
No abstract text is available yet for this article.
17, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27832235/influence-of-heart-failure-on-resting-lung-volumes-in-patients-with-copd
#17
Aline Soares de Souza, Priscila Abreu Sperandio, Adriana Mazzuco, Maria Clara Alencar, Flávio Ferlin Arbex, Mayron Faria de Oliveira, Denis Eunan O'Donnell, José Alberto Neder
Objective: To evaluate the influence of chronic heart failure (CHF) on resting lung volumes in patients with COPD, i.e., inspiratory fraction-inspiratory capacity (IC)/TLC-and relative inspiratory reserve-[1 - (end-inspiratory lung volume/TLC)]. Methods: This was a prospective study involving 56 patients with COPD-24 (23 males/1 female) with COPD+CHF and 32 (28 males/4 females) with COPD only-who, after careful clinical stabilization, underwent spirometry (with forced and slow maneuvers) and whole-body plethysmography...
July 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27812677/influence-of-angiotensin-converting-enzyme-gene-polymorphism-on-echocardiographic-data-of-patients-with-ischemic-heart-failure
#18
Gustavo Salgado Duque, Dayse Aparecida da Silva, Felipe Neves de Albuquerque, Roberta Siuffo Schneider, Alinne Gimenez, Roberto Pozzan, Ricardo Mourilhe Rocha, Denilson Campos de Albuquerque
Background: Association between angiotensin-converting-enzyme (ACE) gene polymorphisms and different clinical and echocardiographic outcomes has been described in patients with heart failure (HF) and coronary artery disease. Studying the genetic profile of the local population with both diseases is necessary to assess the occurrence of that association. Objectives: To assess the frequency of ACE gene polymorphisms in patients with ischemic HF in a Rio de Janeiro population, as well as its association with echocardiographic findings...
November 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27812676/cardiac-cachexia-perspectives-for-prevention-and-treatment
#19
Marina Politi Okoshi, Rafael Verardino Capalbo, Fernando G Romeiro, Katashi Okoshi
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its occurrence predicts increased morbidity and mortality independent of important clinical variables such as age, ventricular function, or heart failure functional class. The clinical consequences of cachexia are dependent on both weight loss and systemic inflammation, which accompany cachexia development. Skeletal muscle wasting is an important component of cachexia; it often precedes cachexia development and predicts poor outcome in heart failure...
October 27, 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27759832/preclinical-molecular-imaging-development-of-instrumentation-for-translational-research-with-small-laboratory-animals
#20
Jorge Mejia, Ana Claudia Camargo Miranda, Ana Claudia Ranucci Durante, Larissa Rolim de Oliveira, Marycel Rosa Felisa Figols de Barboza, Katerin Taboada Rosell, Daniele Pereira Jardim, Alexandre Holthausen Campos, Marilia Alves Dos Reis, Marcela Forli Catanoso, Orfa Yineth Galvis-Alonso, Francisco Romero Cabral
Objective: To present the result of upgrading a clinical gamma-camera to be used to obtain in vivo tomographic images of small animal organs, and its application to register cardiac, renal and neurological images. Methods: An updated version of the miniSPECT upgrading device was built, which is composed of mechanical, electronic and software subsystems. The device was attached to a Discovery VH (General Electric Healthcare) gamma-camera, which was retired from the clinical service and installed at the Centro de Imagem Pré-Clínica of the Hospital Israelita Albert Einstein...
July 2016: Einstein
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