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https://www.readbyqxmd.com/read/29772190/serum-metal-levels-in-maxillofacial-reconstructive-surgery-patients-a-pilot-study
#1
Louis G Mercuri, Michael Miloro, Anastasia K Skipor, Divya Bijukumar, Cortino Sukotjo, Mathew T Mathew
PURPOSE: The aim of this pilot study was to assay metal concentrations in the serum of patients who had undergone dental implant placement, orthognathic surgery using rigid metal fixation plates and screws, and total temporomandibular joint replacement (TMJ TJR). MATERIALS AND METHODS: Thirty patients were identified and included in this pilot study. Sixteen patients (9 men and 8 women), with an average age of 44 years (range, 19 to 79 yr), provided informed consent to participate and were divided into 3 study groups with 4 patients in each (group 1, orthognathic surgery; group 2, TMJ TJR; and group 3, dental implant placement)...
April 21, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29771399/trends-in-total-hip-arthroplasty-under-the-patient-protection-and-affordable-care-act-a-national-database-analysis-between-2008-and-2015
#2
Jennifer I Etcheson, Nicole E George, Chukwuweike U Gwam, James Nace, Alexander T Caughran, Melbin Thomas, Sana Virani, Ronald E Delanois
The Patient Protection and Affordable Care Act expanded health coverage for low-earning individuals and families. With more Americans having access to care, the use of elective procedures, such as total hip arthroplasty (THA), was expected to increase. Therefore, the aim of this study was to evaluate trends in THA before and after the initiation of the Patient Protection and Affordable Care Act regarding race, age, body mass index, and sex between 2008 and 2015. The National Surgical Quality Improvement Program database was queried for all individuals who had undergone primary THA between 2008 and 2015...
May 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29771396/lyme-arthritis-of-the-pediatric-elbow-a-case-series
#3
David Gendelberg, William L Hennrikus
Most patients with untreated Lyme disease will experience joint symptoms. Owing to their resemblance in clinical presentation, Lyme arthritis and septic arthritis are often difficult to differentiate. However, their treatment is different. The elbow is rarely the first joint to present with symptoms. Therefore, Lyme disease is not commonly included in the differential diagnosis for children presenting with isolated elbow pain. The authors report 4 cases of monoarticular Lyme arthritis presenting in the elbow...
May 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29770174/a-simple-technique-to-prolong-molding-time-during-application-of-a-fiberglass-cast-an-in-vitro-study
#4
Mark Ayzenberg, Michael Narvaez, James Raphael
Casting is routinely used for acute and post-operative immobilization and remains a cornerstone in the non-operative management of fractures and deformities. The application of a properly fitted and wellmolded cast, especially for a trainee, can be challenging. We present a simple method of prolonging cure time of fiberglass cast - placing ice in the dip water. Eight-ply, fiveinch fiberglass cast was circumferentially applied to an aluminum-wrapped cardboard cylinder. An electronic, 2-channel temperature sensor (TR-71wf Temp Logger, T&D Corporation, Matsumoto, Japan), accurate to 0...
March 29, 2018: Orthopedic Reviews
https://www.readbyqxmd.com/read/29765192/pinch-aperture-proprioception-reliability-and-feasibility-study
#5
Abdalghani Yahya, Timothy von Behren, Shira Levine, Marcio Dos Santos
[Purpose] To establish the reliability and feasibility of a novel pinch aperture device to measure proprioceptive joint position sense. [Subjects and Methods] Reliability of the pinch aperture device was assessed in 21 healthy subjects. Following familiarization with a 15° target position of the index finger and thumb, subjects performed 5 trials in which they attempted to actively reproduce the target position without visual feedback. This procedure was repeated at a testing session on a separate date, and the between-session intraclass correlation coefficient (ICC) was calculated...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29764301/bioinspired-biocompatible-and-peptide-decorated-silk-fibroin-coatings-for-enhanced-osteogenesis-of-bioinert-implant
#6
Chunyan Wang, Shengnan Wang, Yuanyi Yang, Zhuo Jiang, Yi Deng, Shaoli Song, Weizhong Yang, Zhi-Gang Chen
In this study, we develop an osteopromotive polyetheretherketone (PEEK) implant decorated with silk fibroin and bone forming peptide, in which the surface of bioinert PEEK implant is firstly sulfonated to form a three-dimensional, porous topography and then is functionalized with silk fibroin via spin-coating process and peptide decoration. The bio-test results show that cells on the functional bioinert implants exhibit better cell adhesion, proliferation and spreading, when compared with the uncoated ones...
May 15, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29760814/short-exposures-to-an-extremely-low-frequency-magnetic-field-elf-mf-enhance-protein-but-not-mrna-alkaline-phosphatase-expression-in-human-osteosarcoma-cells
#7
Tania Rescigno, Anna Capasso, Bruno Bisceglia, Mario Felice Tecce
Background: Among electromagnetic fields treatments used in orthopedics, extremely low-frequency magnetic fields (ELF MF) need more detailed information about the molecular mechanisms of their effects and exposure conditions. Objective: Evaluation of the effects of an ELF MF exposure system, recently introduced among current clinical treatments for fracture healing and other bone diseases, on Alkaline Phosphatase (ALP) activity and expression in a human osteosarcoma cell line (SaOS-2), as marker typically associated to osteogenesis and bone tissue regeneration...
2018: Open Biochemistry Journal
https://www.readbyqxmd.com/read/29750599/peri-operative-nasal-eradication-therapy-prevents-staphylococcus-aureus-surgical-site-infections-in-aortoiliac-surgery
#8
Jasper C M Langenberg, Jan A J W Kluytmans, Paul G H Mulder, Jannie Romme, Gwan H Ho, Lyckle Van Der Laan
BACKGROUND: Surgical site infections (SSIs) cause considerable morbidity and deaths among patients undergoing vascular surgery. Pre-operative screening and subsequent treatment of nasal Staphylococcus aureus carriers with mupirocin and chlorhexidine reduces the risk of SSIs in cardiothoracic and orthopedic surgery. The aim of this study was to investigate the effect of this screen-and-treat strategy on the development of SSI in patients undergoing aortoiliac surgery. METHODS: A prospective study was performed that enrolled an intervention cohort comprising all patients undergoing aortoiliac surgery from February 2013 to December 2016...
May 11, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29744925/microcalorimetric-detection-of-staphylococcal-biofilm-growth-on-various-prosthetic-biomaterials-after-exposure-to-daptomycin
#9
Christen Ravn, Inês Santos Ferreira, Elena Maiolo, Søren Overgaard, Andrej Trampuz
Primary aim of this in vitro study was to test the efficacy of daptomycin to eradicate staphylococcal biofilms on various orthopedic implant materials. Secondary aim was to quantitatively estimate the formation of staphylococcal biofilm. We tested six clinically important biomaterials: cobalt chrome, pure titanium, grid-blasted titanium, porous plasma-coated titanium with/without hydroxyapatite, and polyethylene. Biofilms of S. aureus and S. epidermidis were formed on the samples and thereafter exposed to daptomycin...
May 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29744461/fabrication-and-characterization-of-biodegradable-mg-zn-y-nd-ag-alloy-microstructure-mechanical-properties-corrosion-behavior-and-antibacterial-activities
#10
Yashan Feng, Shijie Zhu, Liguo Wang, Lei Chang, Yachen Hou, Shaokang Guan
Magnesium (Mg), a potential biodegradable material, has drawn wide attention in the bone reconstruction field. However, Mg alloys, served as the bone graft substitution, remain a clinical challenge, the antibacterial activity of which is required to be enhanced. Here, we prepared biodegradable magnesium Mg-Zn-Y-Nd-Ag and then had it been further densified by extruding. The microstructure evolution of the as-cast and as-extruded Mg- Zn-Y-Nd-Ag was characterized using optical microscope and X-ray diffraction analyses (XRD)...
September 2018: Bioactive Materials
https://www.readbyqxmd.com/read/29742633/nonsurgical-admissions-with-traumatic-injury-medical-patients-are-trauma-patients-too
#11
Laura Nelson, Sally Kuzniewski, Michael Grossman, Jay A Yelon, Lisa Szydziak
Nontrauma service (NTS) admissions are an increasing problem as ground-level falls in elderly patients become more common. The admission and evaluation of trauma patients to nontrauma services in trauma centers seeking American College of Surgeons (ACS) verification, must follow the ACS mandates for performance improvement requiring some method of evaluating this population when admitted to services other than trauma, orthopedics, and neurosurgery. The purpose of this study and performance improvement project was to improve our process for the definition and evaluation of trauma patients who were being admitted to nontrauma services...
May 2018: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/29740783/anxiety-in-the-orthopedic-patient-using-promis-to-assess-mental-health
#12
Casey M Beleckas, Heidi Prather, Jason Guattery, Melissa Wright, Michael Kelly, Ryan P Calfee
PURPOSE: This study explored the performance of the Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety assessment relative to the Depression assessment in orthopedic patients, the relationship between Anxiety with self-reported Physical Function and Pain Interference, and to determine if Anxiety levels varied according to the location of orthopedic conditions. METHODS: This cross-sectional evaluation analyzed 14,962 consecutive adult new-patient visits to a tertiary orthopedic practice between 4/1/2016 and 12/31/2016...
May 8, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29736095/repair-of-critical-sized-rat-calvarial-defects-with-three-dimensional-hydroxyapatite-gelatin-scaffolds-and-bone-marrow-stromal-stem-cells
#13
Hatef Ghasemi Hamidabadi, Majid Malekzadeh Shafaroudi, Morteza Seifi, Maryam Nazm Bojnordi, Masume Behruzi, Mazaher Gholipourmalekabadi, Ali Malekzadeh Shafaroudi, Nourollah Rezaei
Introduction: The repair of critical-sized defects (CSDs) are one of the most challenging orthopedic problems and the attempts for development of an ideal scaffold for treatment of large bone defect are ongoing. Aim: The aim of this study was the effectiveness of hydroxyapatite-gelatin seeded with bone marrow stromal cells construct for healing of critical-sized bone defect in vivo. Material and Methods: In this experimental study, the bone marrow stromal cells (BMSCs) were isolated by flushing method...
April 2018: Medical Archives
https://www.readbyqxmd.com/read/29735473/exercise-therapy-interventions-in-patients-with-hip-osteoarthritis-comparison-of-the-effects-of-dvd-and-website-based-interventions
#14
Yuko Uesugi, Junichiro Koyanagi, Keishi Takagi, Ryota Yamaguchi, Shinya Hayashi, Takashi Nishii
BACKGROUND: Prevalence of developmental hip dysplasia is high in Japan. Exercise therapy has been proven effective to treat certain aspects of hip osteoarthritis. Moreover, therapy provided via digital video discs (DVDs) and websites allows patients to exercise in the comfort of their own homes. However, no studies have evaluated the effectiveness of visual instructions in patients with hip disorders. OBJECTIVE: This study aimed to compare the effectiveness of exercise therapy administered via DVD and that administered via a website...
May 7, 2018: JMIR Rehabilitation and Assistive Technologies
https://www.readbyqxmd.com/read/29730101/use-of-eos%C3%A2-low-dose-biplanar-x-ray-for-shunt-series-in-children-with-hydrocephalus-a-preliminary-study
#15
Liat Ben-Sira, Shelly I Shiran, Li-Tal Pratt, Ronit Precel, Ovadia, Shlomi Constantini, Jonathan Roth
INTRODUCTION: Shunt series (SS) are a common diagnostic tool used to verify shunt integrity. SS include X-ray films of the skull, chest, and abdomen, and are often performed either when a shunted patient presents with suspected shunt malfunction, or as a screening test to identify shunt disconnections or dislodgment. EOS low-dose biplanar X-rays are associated with significantly reduced radiation doses compared to ordinary X-rays, and are used for various indications. This is the first publication on the use of EOS as a SS technique...
May 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29724468/trends-in-isolated-meniscus-repair-and-meniscectomy-in-japan-2011-2016
#16
Hisako Katano, Hideyuki Koga, Nobutake Ozeki, Koji Otabe, Mitsuru Mizuno, Makoto Tomita, Takeshi Muneta, Ichiro Sekiya
BACKGROUND: Meniscus surgery is the most commonly performed orthopedic surgery, and despite recent emphasis on saving the meniscus, the current status of meniscus surgeries is little known in many countries, including Japan. The National Database of Health Insurance Claims and Specific Health Checkups of Japan and the Statistics of Medical Care Activities in Public Health Insurance track meniscus surgeries through health insurance claims. The National Database provides the numbers for 2014 and 2015, and the Statistics of Medical Care Activities provides the numbers from June 2011 to June 2016...
April 30, 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29719605/-in-vivo-safety-and-efficacy-testing-of-a-thermally-triggered-injectable-hydrogel-scaffold-for-bone-regeneration-and-augmentation-in-a-rat-model
#17
Abbey A Thorpe, Christine Freeman, Paula Farthing, Jill Callaghan, Paul V Hatton, Ian M Brook, Chris Sammon, Christine Lyn Le Maitre
Bone loss resulting from degenerative diseases and trauma is a significant clinical burden which is likely to grow exponentially with the aging population. In a number of conditions where pre-formed materials are clinically inappropriate an injectable bone forming hydrogel could be beneficial. The development of an injectable hydrogel to stimulate bone repair and regeneration would have broad clinical impact and economic benefit in a variety of orthopedic clinical applications. We have previously reported the development of a Laponite® crosslinked pNIPAM-co-DMAc (L-pNIPAM-co-DMAc) hydrogel delivery system, loaded with hydroxyapatite nanoparticles (HAPna), which was capable of inducing osteogenic differentiation of mesenchymal stem cells (MSCs) without the need for additional growth factors in vitro ...
April 6, 2018: Oncotarget
https://www.readbyqxmd.com/read/29719124/graphene-oxide-decorated-microporous-polyetheretherketone-with-superior-antibacterial-capability-and-in-vitro-osteogenesis-for-orthopedic-implant
#18
Ling Ouyang, Yi Deng, Lei Yang, Xiuyuan Shi, Taosheng Dong, Youyi Tai, Weizhong Yang, Zhi-Gang Chen
Due to its similar elastic modulus of human bones, polyetheretherketone (PEEK) has been considered as an excellent cytocompatible material. However, the bioinertness, poor osteoconduction, and weak antibacterial activity of PEEK limit its wide applications in clinics. In this study, a facile strategy is developed to prepare graphene oxide (GO) modified sulfonated polyetheretherketone (SPEEK) (GO-SPEEK) through a simple dip-coating method. After detailed characterization, it is found that the GO closely deposits on the surface of PEEK, which is attributed to the π-π stacking interaction between PEEK and GO...
May 2, 2018: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29712650/activity-of-combinations-of-antistaphylococcal-antibiotics-with-fusidic-acid-against-staphylococcal-biofilms-in-in-vitro-static-and-dynamic-models
#19
Wafi Siala, Hector Rodriguez-Villalobos, Prabhavathi Fernandes, Paul M Tulkens, Françoise Van Bambeke
Staphylococcal biofilms are a major cause of therapeutic failure, especially when caused by multiresistant strains. Oral fusidic acid is currently being re-developed in the US for skin and skin structure and orthopedic infections, in which biofilms play a major role. The aim of this study was to examine the activity of fusidic acid alone or combined with other anti-staphylococcal drugs against biofilms made by a reference strain and five clinical isolates of Staphylococcus aureus or Staphylococcus epidermidis in in vitro static or dynamic models (microtiter plates and CDC reactor) exposed to clinically-relevant concentrations...
April 30, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29708573/medial-compartment-decompression-by-proximal-fibular-osteotomy-a-biomechanical-cadaver-study
#20
Todd Baldini, Jesse Roberts, Jiandong Hao, Kenneth Hunt, Michael Dayton, Craig Hogan
Medial compartment knee osteoarthritis is a painful and debilitating disease. A proximal fibular osteotomy is a novel, simple surgical technique that may reduce pain and improve function for patients with osteoarthritis. The purpose of this biomechanical cadaver study was to determine what effect proximal fibular osteotomy had on knee joint and ankle pressures and tibia strain. Ten matched pairs of cadaver legs were tested in compression to 1.1 times body weight comparing intact and with proximal fibular osteotomy at 0°, 15°, and 30° of flexion...
April 27, 2018: Orthopedics
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