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https://www.readbyqxmd.com/read/29160517/prevalence-and-antibiogram-of-methicillin-resistant-staphylococcus-aureus-isolated-from-medical-device-related-infections-a-retrospective-study-in-lahore-pakistan
#1
Muhammad Sohail, Zakia Latif
INTRODUCTION: With the advancement of medicine and surgery, various types of medical devices have become part of treatment strategies. METHODS: Identification and antimicrobial sensitivity testing were done according to CLSI guidelines following standard microbiological practices. RESULTS: Urinary catheter infections (31%) were most frequent followed by central venous catheter (18%) and orthopedic implants (15%). Methicillin resistant Staphylococcus aureus (MRSA) was a major cause of device-related infection after Escherichia coli (21%); other pathogens were Klebsiella pneumoniae (14%), Pseudomonas spp...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29159731/effects-of-population-variability-on-knee-loading-during-simulated-human-gait
#2
Rebecca J Nesbitt, Nathaniel A Bates, Marepalli B Rao, Grant Schaffner, Jason T Shearn
Cadaveric simulation models allow researchers to study native tissues in situ. However, as tests are conducted using donor specimens with unmatched kinematics, techniques that impose population average motions are subject to deviation from true physiologic conditions. This study aimed to identify factors which explain the kinetic variability observed during robotic simulations of a single human gait motion using a sample of human cadaver knees. Twelve human cadaver limbs (58 ± 16 years) were subjected to tibiofemoral geometrical analysis and cyclical stiffness testing in each anatomical degree of freedom...
November 20, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29156068/lmwf-5a-for-the-treatment-of-severe-osteoarthritis-of-the-knee-integrated-analysis-of-safety-and-efficacy
#3
Brian Cole, Brian McGrath, Kristin Salottolo, David Bar-Or
The low-molecular-weight fraction of 5% human serum albumin (LMWF-5A) is being developed to treat the signs and symptoms of severe osteoarthritis of the knee. This study was a post hoc pooled analysis of 3 randomized placebo-controlled trials of a single intra-articular injection of LMWF-5A, focusing on the subset of patients with severe osteoarthritis of the knee (Kellgren-Lawrence grade 4). Patients were randomized 1:1 to receive a single 4-mL intra-articular knee injection of either LMWF-5A or saline. Safety was assessed as the incidence and severity of adverse events...
November 20, 2017: Orthopedics
https://www.readbyqxmd.com/read/29149204/evaluation-of-osseous-integration-of-titanium-orthopedic-screws-with-novel-sla-treatment-in-porcine-model
#4
Tzu-Hsiang Lin, Hsin-Tai Hu, Hsueh-Chun Wang, Meng-Chian Wu, Shu-Wei Wu, Ming-Long Yeh
The success of many endosseous implants in orthopaedic and dental applications depends on the surface characteristics, as they affect osseous integration. Previous investigations indicated that a novel large-grit sand-blasted and acid-etched (SLA) titanium (denoted as SLAffinity-Ti) implant had better bone integration than that of a comparably shaped implant with a plasma-sprayed titanium surface. The purpose of the present investigation was to create a SLAffinity surface on pedicle screws and trauma screws and to compare it with the surfaces of a sand-blasted-only implant and commercial implants in terms of bone integration...
2017: PloS One
https://www.readbyqxmd.com/read/29140371/biofunctionalization-of-titanium-granules-with-simvastatin-for-improving-osteogenic-activity-and-antibacterial-properties-ex-vivo-study
#5
Zahra Gorgin Karaji, Behzad Houshmand, Shahsanam Abbasi, Sara Shafiei, Shahab Faghihi
PURPOSE: Titanium-based biomaterials present good biocompatibility, while their osseointegration and antibacterial properties need to be improved. This study aimed to enhance the bone-bonding ability of titanium-based granules, which are intended to be used as bone graft. MATERIALS AND METHODS: The titanium granules were anodized in ethylene glycol-based electrolyte and subsequently annealed to be loaded separately with simvastatin. The samples were then inspected with attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) for drug loading...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140170/clinical-diagnostic-tests-versus-mri-diagnosis-of-acl-tears
#6
Megan P Brady, Windee Weiss
CLINICAL SCENARIO: A common injury among elite, recreational, and youth athletes is the anterior cruciate ligament (ACL) tear.(1) Approximately 200,000 ACL injuries occur every year.(2) The gold standard in ACL injury evaluation is diagnostic arthroscopy,(3,4) however the diagnostic accuracy of clinical diagnostic tests and magnetic resonance imaging (MRI) is debatable.(1,3-6) Due to the frequency of knee injury,(3) MRI is a common diagnostic tool used for imaging and diagnosis(5). ACL tears are also diagnosed using clinical diagnostic tests...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29136255/loss-of-internal-tibial-rotation-after-anterior-cruciate-ligament-reconstruction
#7
Shawn R Brandenburg, Thomas M Matelic
The flexion angle of the knee and the position of the tibia need to be considered during tensioning of the anterior cruciate ligament (ACL) graft to avoid overconstraining the knee. The purpose of this report was to describe 2 cases of loss of tibial internal rotation after single-bundle anatomic ACL reconstruction with graft tensioning in flexion. Retrospective review of each patient's operative chart revealed that the graft was tensioned in flexion and placed in an anatomic position in the femoral tunnel at the time of the index operation...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29136253/fatty-degeneration-of-the-rotator-cuff-reflects-shoulder-strength-deficits-in-patients-with-rotator-cuff-tears
#8
Jong Pil Yoon, Jae Wook Jung, Chang Hwa Lee, Young Gun Kim, Seok Won Chung, Joon Yub Kim, Hyun Joo Lee, Jee Wook Yoon, Hoseok Lee
Fatty degeneration is an important clinical factor in patients with rotator cuff tears. Goutallier grade, occupation ratio, and tangent sign help identify fatty degeneration; however, little is known about how closely these measurement techniques correlate with actual muscle strength deficits. The authors evaluated each method's ability to determine the correlation between fatty degeneration and muscle strength deficits. The authors included 203 patients who underwent full-thickness rotator cuff repair (mean age, 61...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29134156/preoperative-cervical-sagittal-alignment-parameters-and-their-impacts-on-myelopathy-in-patients-with-cervical-spondylotic-myelopathy-a-retrospective-study
#9
Wei Yuan, Yue Zhu, Haitao Zhu, Cui Cui, Lei Pei, Zhuxi Huang
Background: Cervical sagittal alignment plays an important role in the pathogenesis of cervical spondylotic myelopathy (CSM), but there are limited studies on the cervical sagittal parameters in CSM patients and their correlations with myelopathy. The aim of this study is to investigate the correlations among the preoperative cervical sagittal alignment parameters and their correlations with the development of myelopathy in patients with CSM. Methods: We retrospectively collected 212 patients with CSM who underwent surgical interventions...
2017: PeerJ
https://www.readbyqxmd.com/read/29133972/the-relationship-between-the-physical-cost-index-and-knee-extensor-strength-in-children-with-hemiplegic-cerebral-palsy
#10
Kenji Takaki, Yasuaki Kusumoto
[Purpose] Lower extremity strength is a contributing factor to energy efficiency of gait. However, this contribution has not previously been evaluated in children with hemiplegic cerebral palsy (CP). The aim of this study was to evaluate the association between energy consumption, measured by the physical cost index (PCI), and strength of lower extremity, measured by the maximum knee extensor strength (MKES), in children with hemiplegic CP. [Subjects and Methods] Subjects were 10 children (4 males and 6 females; age, 7-17 years) with hemiplegic CP, but no history of orthopedic intervention or botulinum toxin treatment over the 1 year prior to the assessment...
October 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29125861/identification-of-hospitalized-elderly-patients-at-risk-for-adverse-in-hospital-outcomes-in-a-university-orthopedics-and-trauma-surgery-environment
#11
Janine Gronewold, Christian Dahlmann, Marcus Jäger, Dirk M Hermann
BACKGROUND: As a consequence of demographic changes, hospitals are confronted with increasing numbers of elderly patients, who are at high risk of adverse events during hospitalization. Geriatric risk screening followed by comprehensive geriatric assessment (CGA) and treatment has been requested by geriatric societies and task forces to identify patients at risk. Since empirical evidence on factors predisposing to adverse hospital events is scarce, we now prospectively evaluated implications of geriatric risk screening followed by CGA in a university hospital department of orthopedics and trauma surgery...
2017: PloS One
https://www.readbyqxmd.com/read/29122570/relationships-between-facial-divergence-and-dmd-parameters
#12
Abdelali Halimi, Hicham Benyahia, Mohamed-Faouzi Azeroual, Loubna Bahije, Fatima Zaoui
INTRODUCTION: The aim of this study was to examine the relationship between facial divergence and the parameters of dentomaxillary discrepancy (DMD), in particular crowding, the curve of Spee and the position of the incisors in the sagittal dimension. MATERIAL AND METHODS: A total of 90 young adult patients was selected from among the Moroccan orthodontic population attending the dentofacial orthopedic department and satisfying the following inclusion criteria: complete permanent dentition and a skeletal class I pattern with no previous orthodontic treatment, no crossbite, no periodontal disease, no mandibular asymmetry and no condylodiscal disunion...
November 6, 2017: International Orthodontics
https://www.readbyqxmd.com/read/29118579/surface-modification-of-vascular-endothelial-growth-factor-loaded-silk-fibroin-to-improve-biological-performance-of-ultra-high-molecular-weight-polyethylene-via-promoting-angiogenesis
#13
Chengchong Ai, Dandan Sheng, Jun Chen, Jiangyu Cai, Siheng Wang, Jia Jiang, Shiyi Chen
Ultra-high-molecular-weight polyethylene (UHMWPE) has been applied in orthopedics, as the materials of joint prosthesis, artificial ligaments, and sutures due to its advantages such as high tensile strength, good wear resistance, and chemical stability. However, postoperative osteolysis induced by UHMWPE wear particles and poor bone-implant healing interface due to scarcity of osseointegration is a significant problem and should be solved imperatively. In order to enhance its affinity to bone tissue, vascular endothelial growth factor (VEGF) was loaded on the surface of materials, the loading was performed by silk fibroin (SF) coating to achieve a controlled-release delivery...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29116328/correlation-between-femoroacetabular-impingement-and-hamstring-tendon-pathology-on-magnetic-resonance-imaging-and-arthrography
#14
Nakul Talathi, Scott LaValva, Angel Lopez-Garib, John D Kelly, Viviane Khoury
Femoroacetabular impingement (FAI) is an abnormality of the femoral head or acetabulum that leads to an increased incidence of cartilaginous injury in the hip. Femoroacetabular impingement has been associated with several structural abnormalities, including osteitis pubis and hip flexor dysfunction. The authors propose that, additionally, FAI may lead to increased damage of the hamstring tendon due to the additional stress placed on the tendon from the limited range of motion of the hip. The authors conducted a retrospective matched-pair study with the magnetic resonance imaging and magnetic resonance arthrography images of 40 patients' hamstrings with FAI and 45 age-matched controls...
November 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/29116326/performance-comparison-of-single-radius-versus-multiple-curve-femoral-component-in-total-knee-arthroplasty-a-prospective-randomized-study-using-the-lower-quarter-y-balance-test
#15
Samuel S Wellman, Mitchell R Klement, Robin M Queen
Midflexion stability after total knee arthroplasty (TKA) is dependent, in part, on implant design. Midflexion performance of a single-radius (SR) design and a multi-radius, or J-curve (JC), design were compared using the Lower Quarter Y-Balance Test (YBT-LQ). Patient-reported outcomes and measures of physical performance were also compared. The authors hypothesized that the SR design would provide superior midflexion stability and, therefore, a greater reach distance in the YBT-LQ when compared with the JC design...
November 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/29115921/identifying-protective-and-risk-factors-for-injurious-falls-in-patients-hospitalized-for-acute-care-a-retrospective-case-control-study
#16
Emmanuel Aryee, Spencer L James, Guenola M Hunt, Hilary F Ryder
BACKGROUND: Admitted patients who fall and injure themselves during an acute hospitalization incur increased costs, morbidity, and mortality, but little research has been conducted on identifying inpatients at high risk to injure themselves in a fall. Falls risk assessment tools have been unsuccessful due to their low positive predictive value when applied broadly to entire hospital populations. We aimed to identify variables associated with the risk of or protection against injurious fall in the inpatient setting...
November 7, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29103444/long-term-stability-of-class-ii-treatment-with-the-jasper-jumper-appliance
#17
Camilla Fiedler Foncatti, José Fernando Castanha Henriques, Guilherme Janson, Waleska Caldas, Daniela Gamba Garib
INTRODUCTION: Treatment of Class II Division 1 malocclusion with orthopedic devices combined with fixed orthodontic appliances has shown excellent results when used in growing patients. We aimed to evaluate the long-term stability of the cephalometric changes obtained during Class II malocclusion correction with the Jasper jumper associated with fixed appliances. METHODS: The treatment group comprised 24 patients who were evaluated at 3 stages: pretreatment, posttreatment, and long-term posttreatment...
November 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29101896/a-simplified-application-app-for-the-parametric-design-of-screw-plate-fixation-of-bone-fractures
#18
Chen-Yuan Chung
Screw and plate fixation is commonly used to treat bone fractures. A prototype application (APP) for presurgical simulation was developed and validated by comparing it with current analytical approach and other models. In this APP, alternative plate designs and materials to limit the effects of stress shielding could be tested. In addition, the number and position of screws and the gap between bone and plate that achieved acceptable stability were predicted. The fixation stability providing a situation of interfragmentary strain between 2% and 10% is necessary for callus formation...
November 1, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29100205/influence-of-cement-compressive-strength-and-porosity-on-augmentation-performance-in-a-model-of-orthopedic-screw-pull-out
#19
Michael Pujari-Palmer, Celine Robo, Cecilia Persson, Philip Procter, Håkan Engqvist
Disease and injuries that affect the skeletal system may require surgical intervention and internal fixation, i.e. orthopedic plate and screw insertion, to stabilize the injury and facilitate tissue repair. If the surrounding bone quality is poor the screws may migrate, or the bone may fail, resulting in fixation failure. While numerous studies have shown that cement augmentation of the interface between bone and implant can increase screw pull-out force, the physical properties of cement that influence pull-out force have not been investigated...
October 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29096664/kinetic-gait-analysis-in-english-bulldogs
#20
Andrés Sebastian Aristizabal Escobar, Alexandre Navarro Alves de Souza, Ana Carolina Brandão de Campos Fonseca Pinto, Julia Maria Matera
BACKGROUND: Canine breed conformation may interfere with locomotion and may predispose to orthopedic disease. Bulldogs have a high incidence of orthopedic diseases such as hip dysplasia. Kinetic gait analysis provides an objective way to assess and analyze locomotion. The aim of this study was to study the vertical forces of English Bulldogs during walk using a pressure sensitive walkway. We hypothesize that Bulldogs affected by orthopedic diseases have decreased weight bearing and asymmetric locomotion in the limbs despite having mild to no sings during clinical examination...
November 2, 2017: Acta Veterinaria Scandinavica
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