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https://www.readbyqxmd.com/read/28433416/static-postural-control-in-youth-with-osteogenesis-imperfecta-type-i
#1
Annie Pouliot-Laforte, Martin Lemay, Frank Rauch, Louis-Nicolas Veilleux
OBJECTIVE: To assess static postural control in eyes-open and eyes-closed conditions in individuals with osteogenesis imperfecta (OI) type I as compared to typically developing (TD) individuals. The second aim was to explore the relation between postural control and lower-limbs muscle function. DESIGN: This is a cross-sectional study. SETTINGS: The study was carried out in the outpatient department of a pediatric orthopedic hospital. PARTICIPANTS: 22 individuals with OI type I (mean age [range]: 13...
April 19, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28430741/utility-of-8%C3%A2-h-and-time-decay-corrected-acquisition-scintigraphy-with-in-vitro-labeled-white-blood-cells-for-the-diagnosis-of-osteoarticular-infection
#2
Edel Noriega Álvarez, Guillermo A Martínez Pimienta, Ana M Benítez Segura, María T Bajén Lázaro, Alba Rodrígez-Gasén, Julio Rodríguez-Rubio Corona, Jaime Mora Salvadó
INTRODUCTION: Except in the spine, labeled white-blood cell scintigraphy (WBCS) with image acquisition up to 24 h is the nuclear medicine test of choice for diagnosing osteoarticular infection. However, distinguishing between inflammation and infection is a challenge. OBJECTIVES: The first aim of this study was to verify earlier research studies that used 4 and 24 h time decay-corrected acquisition (TDCA) to differentiate infection from inflammation. The second aim was to analyze whether 8 h acquisition (1-day protocol) yielded similar results as 20-24 h acquisition...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28428212/a-novel-mri-biomarker-of-spinal-cord-white-matter-injury-t2-weighted-white-matter-to-gray-matter-signal-intensity-ratio
#3
A R Martin, B De Leener, J Cohen-Adad, D W Cadotte, S Kalsi-Ryan, S F Lange, L Tetreault, A Nouri, A Crawley, D J Mikulis, H Ginsberg, M G Fehlings
BACKGROUND AND PURPOSE: T2*-weighted imaging provides sharp contrast between spinal cord GM and WM, allowing their segmentation and cross-sectional area measurement. Injured WM demonstrates T2*WI hyperintensity but requires normalization for quantitative use. We introduce T2*WI WM/GM signal-intensity ratio and compare it against cross-sectional area, the DTI metric fractional anisotropy, and magnetization transfer ratio in degenerative cervical myelopathy. MATERIALS AND METHODS: Fifty-eight patients with degenerative cervical myelopathy and 40 healthy subjects underwent 3T MR imaging, covering C1-C7...
April 20, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28428032/does-semi-automatic-bone-fragment-segmentation-improve-the-reproducibility-of-the-letournel-acetabular-fracture-classification
#4
M Boudissa, B Orfeuvre, M Chabanas, J Tonetti
BACKGROUND: The Letournel classification of acetabular fracture shows poor reproducibility in inexperienced observers, despite the introduction of 3D imaging. We therefore developed a method of semi-automatic segmentation based on CT data. The present prospective study aimed to assess: 1) whether semi-automatic bone-fragment segmentation increased the rate of correct classification; 2) if so, in which fracture types; and 3) feasibility using the open-source itksnap 3.0 software package without incurring extra cost for users...
April 17, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28427393/correlation-between-intervertebral-disc-degeneration-paraspinal-muscle-atrophy-and-lumbar-facet-joints-degeneration-in-patients-with-lumbar-disc-herniation
#5
Dong Sun, Peng Liu, Jie Cheng, Zikun Ma, Jingpei Liu, Tingzheng Qin
BACKGROUND: To assess the correlation between lumbar disc degeneration (LDD), multifidus muscle atrophy (LMA), and facet joints degeneration in patients with L4-L5 lumbar disc herniation (LDH). METHODS: Sixty patients with L4-L5 LDH diagnosed by a 1.5 T MRI scanner were enrolled in the study group and another 60 patients with non-specific back pain were enrolled in the control group. LDD, LMA, and facet joints degeneration were examined and analyzed independently by two independent orthopedic surgeons using T2-weighted images...
April 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28423488/mmp8-polymorphism-is-associated-with-susceptibility-to-osteonecrosis-of-the-femoral-head-in-a-chinese-han-population
#6
Feimeng An, Jieli Du, Yuju Cao, Jianping Shi, Yongchang Guo, Tianbo Jin, Jian Li, Junyu Chen, Ping Li, Mei Dong, Guoqiang Wang, Jianzhong Wang
Osteonecrosis of the femoral head (ONFH) is an orthopedic refractory disease that adversely affects quality of life. Matrix metalloproteinase-8 (MMP-8) produced by the bone marrow has been implicated in the degradation of collagen during bone development. We assessed whether MMP8 polymorphisms are associated with ONFH. In a case-control study, using χ2 tests and genetic model analyses, we genotyped 5 MMP8 single-nucleotide polymorphisms (SNPs) in 585 ONFH patients and 507 healthy control subjects in a Chinese Han population...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28416189/the-validity-and-reliability-of-the-arabic-version-of-the-japanese-orthopedic-association-back-pain-evaluation-questionnaire-can-we-implement-it-in-saudi-arabia-study-design-cross-sectional-study
#7
Saud Mohammed Alfayez, Abdullah Nasser Bin Dous, Abdullah Abdulaziz Altowim, Qais Abdulmohsin Alrabiei, Bandar Obaid Alsubaie, Waleed Mohammad Awwad
BACKGROUND: The Japanese Orthopedic Association designed their back pain evaluation questionnaire (JOABPEQ) which was proven to be feasible, reliable and valid. The questionnaire's validity and reliability were confirmed when it was implemented in patients with different cultural background. Since the JOABPEQ still has not been utilized in any of the Arabic countries, we present the Arabic version with its validity and reliability. METHODS: After ensuring an optimal forward-backward translation of the JOABPEQ, the Arabic version was distributed among 151 patients visiting our clinics from December 2015 to February 2016...
April 13, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28415528/improved-biotribological-properties-of-peek-by-photo-induced-graft-polymerization-of-acrylic-acid
#8
Xiaoduo Zhao, Dangsheng Xiong, Kun Wang, Nan Wang
The keys of biomaterials application in artificial joints are good hydrophilicity and wear resistance. One kind of the potential bio-implant materials is polyetheretherketone (PEEK), which has some excellent properties such as non-toxic and good biocompatibility. However, its bioinert surface and inherent chemical inertness hinder its application. In this study, we reported an efficient method for improving the surface wettability and wear resistance for PEEK, a layer of acrylic acid (AA) polymer brushes on PEEK surface was prepared by UV-initiated graft polymerization...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415419/lsp-mao-composite-bio-coating-on-az80-magnesium-alloy-for-biomedical-application
#9
Ying Xiong, Qiang Hu, Renguo Song, Xiaxia Hu
A composite bio-coating was fabricated on AZ80 magnesium (Mg) alloy by using micro-arc oxidation (MAO) under the pretreatment of laser shock peening (LSP) in order to improve the bio-corrosion resistance and the mechanical integrity. LSP treatment could induce grain refinement and compressive residual stress field on the surface of material. MAO bio-coating was grown in alkaline electrolyte with hydroxyapatite (HA, Ca10(PO4)6(OH)2) to improve the biological properties of the material. The microstructure, element and phase composition for untreated based material (BM) and treated samples (LSP layer, MAO bio-coating and LSP/MAO composite bio-coating) were investigated by transmission electron microscopy (TEM), scanning electron microscope (SEM), energy dispersion spectroscopy (EDS) and X-ray diffraction (XRD)...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415416/in-vitro-and-in-vivo-corrosion-mechanical-properties-and-biocompatibility-evaluation-of-mgf2-coated-mg-zn-zr-alloy-as-cancellous-screws
#10
Zhen Li, Sun Shizhao, Minfang Chen, Bradley Dean Fahlman, Debao Liu, Hongwei Bi
Magnesium (Mg) and its alloys as biodegradable materials have received much attention in the orthopedics applications; however, the corrosion behavior of these metals in vivo remains challenging. In this work, a dense and nanoscale magnesium fluoride (MgF2) coating was deposited on the surface of Mg-Zn-Zr (MZZ) alloy cancellous screw. The MZZ cancellous screw with MgF2 coating maintained an integrated shape and high yield tensile stress after 30days immersion in SBF, comparing with the bare screw. Hydrogen releasing rate of the MZZ samples was suppressed at a lower level at the initial stage, which is in favour of the adhesion of the cells...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28410285/comorbidities-in-patients-with-chronic-obstructive-pulmonary-disease-and-pulmonary-rehabilitation-outcomes
#11
Pichapong Tunsupon, Ashima Lal, Mohammed Abo Khamis, M Jeffery Mador
PURPOSE: The objective of this study was to evaluate the impact of comorbidities as potential predictors of the response to pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD). METHODS: The study included 165 patients with COPD with exercise limitations. Comorbidity was classified as cardiac, metabolic, orthopedic, behavioral health problems, or other diseases. Number of comorbidities was grouped as 0, 1, or ≥2. Outcomes were defined as improvement in exercise capacity (maximal exercise capacity, 6-minute walk test, and constant workload cycle exercise duration) and quality of life (Chronic Respiratory Questionnaire)...
April 12, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28409146/pindborg-tumor-in-the-distal-femur
#12
Alex Oliboni Sussela, Paulo Ricardo Picon Alves, Vinicius Duval da Silva, Carlos Daniel de Garcia Bolze, Osvaldo André Serafini
To describe a case of possible diagnosis of Pindborg tumor on the distal femur. A 32-years-old female patient, a native of Bolivia, resident in Brazil, arrived to this service for tumor research in the right femur. After biopsies and resection of the lesion, the case was referred to analysis and consultancy in the United States. In a report of review by the Pathology Laboratory, it was characterized the histological appearance and immunohistochemical profile were characteristic of Pindborg tumor. Currently, the patient is being followed-up at the Orthopedics and Traumatology Department of this institution, and presents a good evolution...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28398160/should-young-children-with-tbi-be-compared-to-community-or-orthopedic-control-participants
#13
Miriam Helen Beauchamp, Catherine Landry-Roy, Jocelyn Gravel, Cindy Beaudoin, Annie Bernier
Pediatric traumatic brain injury (TBI) research depends on comparisons of profiles and outcome between brain injured individuals and groups consisting either of injured controls (e.g., orthopedic injuries, OI) or uninjured, typically developing children recruited from the community (community controls, CC). Children with OI are thought to provide optimal comparisons for individuals with TBI because they share injury-related experiences and pre-morbid characteristics; however, a study by Mathias and colleagues (2013) in adults has called into question the added value of injury control groups in TBI research...
April 11, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28390886/epidemiology-and-antibiotic-resistance-of-late-prosthetic-knee-and-hip-infections
#14
Lorenzo Drago, Elena De Vecchi, Monica Bortolin, Luigi Zagra, Carlo L Romanò, Laura Cappelletti
BACKGROUND: Prosthetic joint infections (PJI) are still a major complication of hip and knee arthroplasties. Identification of the causative pathogens and knowledge of their antibiotic susceptibilities are essential for the management of these infections. The main purpose of the study was to identify and compare the causative bacteria of prosthetic knee and hip joint infections in a reference Italian orthopedic center and to characterize antibiotic resistance profiles of bacteria involved...
March 15, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28390756/screening-for-nasal-carriage-of-staphylococcus-aureus-among-patients-scheduled-to-undergo-orthopedic-surgery-incidence-of-surgical-site-infection-by-nasal-carriage
#15
Masaru Nakamura, Tateaki Shimakawa, Shunji Nakano, Takashi Chikawa, Shinji Yoshioka, Masahiro Kashima, Shunichi Toki, Koichi Sairyo
BACKGROUND: Staphylococcus aureus (S. aureus), including MRSA, is considered to be the leading cause of surgical site infection (SSI) after orthopedic surgery. We screened for nasal carriers of S. aureus among patients who were scheduled to undergo orthopedic surgery at our hospital to reveal the effect of nasal S. aureus carriage on SSI. Our study design clearly has the intent of finding S. aureus nasal carriage and eradicating MRSA when found, and this strategy is to verify whether it's effective for preventing orthopedic surgical infections...
April 5, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28390241/decreased-fibrous-encapsulation-and-enhanced-osseointegration-in-vitro-by-decorin-modified-titanium-surface
#16
Ronghan He, Yunxiang Lu, Jianhua Ren, Zhe Wang, Junqi Huang, Lei Zhu, Kun Wang
Orthopedic implants, using materials such as titanium, are extensively used in clinical surgeries. Despite its popularity, titanium is still inadequate to reliable osseointegration due to aseptic loosing. Fibrous encapsulation on the titanium implant interface prevents osseointegration and leads to the loosing of orthopedic implant. In this study, decorin was loaded on titanium surface by polydopamine film to examine fibrous encapsulation inhibition and bone growth acceleration. The coating of decorin was evaluated by X-ray photoelectron spectroscopy (XPS) and fluorescence microscopy...
March 31, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28377012/mental-disorders-in-people-affected-by-thalidomide
#17
Alexander Niecke, Klaus Peters, Christina Samel, Kristin Forster, Markus Lüngen, Holger Pfaff, Christian Albus
BACKGROUND: More than 50 years after the withdrawal of thalidomide from the market, subsequent orthopedic damages and psychosocial impairments dominate the complaints of thalidomide-affected individuals. The aim of the study was to determine the prevalence of mental disorders in this group. METHODS: A total of 193 thalidomide-affected individuals from North Rhine-Westphalia (mean age 50.5 years, 56.5% women) underwent personal and comprehensive psychodiagnostic testing, which was based on the Structured Clinical Interview for DSM-IV disorders (SCID-I & SCID-II) and self-reporting questionnaires...
March 10, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28376907/incidence-of-venous-thromboembolism-and-bleeding-events-in-patients-with-lower-extremity-orthopedic-surgery-a-retrospective-analysis-of-a-japanese-healthcare-database
#18
Takeshi Fuji, Masao Akagi, Yasuyuki Abe, Eisei Oda, Daisuke Matsubayashi, Kaori Ota, Masafumi Kobayashi, Yasuyuki Matsushita, Jumpei Kaburagi, Kei Ibusuki, Atsushi Takita, Mikio Iwashita, Takuhiro Yamaguchi
BACKGROUND: Orthopedic surgeries of lower extremities such as total knee arthroplasty (TKA), total hip arthroplasty (THA), and hip fracture surgery (HFS) are widely considered to carry a high risk of developing deep venous thrombosis (DVT) and pulmonary thromboembolism (PTE). Growing attention to epidemiological studies using a healthcare database led us to quantify the risks using a Japanese database to reveal recent medical care for such events. METHODS: The study comprised 36,947 patients who had undergone orthopedic surgeries of the lower extremities and whose medical information from April 2008 to September 2013 was available...
April 4, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28376529/role-of-direct-oral-anticoagulants-in-the-management-of-anticoagulation
#19
Rajiv N Thakkar, Suman W Rathbun, Scott M Wright
For decades, vitamin K antagonists (VKAs) have been the oral treatment of choice for many thromboembolic conditions. The limitations of VKAs include the need for monitoring through blood testing, drug interactions, and narrow therapeutic windows. These shortcomings have led to the development of direct oral anticoagulants. These new oral agents act on specific targets in the coagulation cascade (eg, factor Xa, thrombin) and negate some of the shortcomings of VKAs. This article reviews the roles of dabigatran, rivaroxaban, apixaban, and edoxaban in stroke prevention in nonvalvular atrial fibrillation, for prevention of venous thromboembolism after orthopedic surgery, and in the treatment of venous thromboembolism...
April 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28374679/in-vitro-study-of-electrodeposited-fluoridated-hydroxyapatite-coating-on-g-ii-titanium-with-a-nanostructured-tio2-interlayer
#20
Jin-Shyong Lin, Tzung-Bau Tsai, Wen-Ching Say, Chun Chiu, Shih-Hsun Chen
Titanium and its alloys have been widely used as orthopedic and dental implants for several decades due to their superior mechanical properties, corrosion resistance and biocompatibility. Recently, many researches revealed that the hydroxyapatite coatings on biomedical materials can further improve their biocompatibility and bioactivity. However, hydroxyapatite coatings are easily decomposed, weakening the bonding between implants and bone tissues and resulting in a high dissolution rate in the biological environment...
April 4, 2017: Biomedical Materials
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