keyword
https://read.qxmd.com/read/38535841/effects-of-designed-herbal-formula-on-growth-performance-blood-indices-organ-traits-and-cecum-microbiology-in-broilers
#1
JOURNAL ARTICLE
Yuelong Sun, Mengjie Zhang, Dongdong Shi, Xiaofeng Dai, Xiumei Li
The objective of this study was to investigate the effect of the designed herbal formula (DHF) on growth performance, blood indices, organ traits, and cecum microbiology in broilers. A total of 96 male broilers of 1 d were selected and randomly assigned to two groups with six replicates of eight broilers each. The control (CON) and the basal diet containing 1.0% DHF ( Astragali radix , Atractylodes macrocephala Koidz., Isatis tinctoria Linnaeus, and Citri reticulatae pericarpium , 2:1:1:2) were fed separately...
February 29, 2024: Veterinary Sciences
https://read.qxmd.com/read/38527414/effects-of-different-supplemental-levels-of-protease-de200-on-the-production-performance-egg-quality-and-cecum-microflora-of-laying-hens
#2
JOURNAL ARTICLE
Peiran Cai, Shiqi Liu, Yuang Tu, Dabo Fu, Wei Zhang, Xixi Zhang, Ying Zhou, Tizhong Shan
This study aimed to investigate the effects of different levels of the protease DE200TM on the performance, egg quality, organ index and cecum microflora of Hy-line W36 laying hens. In this experiment, a total of 180 laying hens aged 300 days were randomly divided into three treatment groups and fed diets containing 0, 100 or 200 g/t DE200. The experimental period was eight weeks, including two weeks of prefeeding and six weeks of the formal experiment. Regular feeding was performed thrice a day and eggs were collected twice daily, and the feed intake and the egg quality were recorded...
March 25, 2024: Journal of Animal Science
https://read.qxmd.com/read/38526568/changes-in-the-structural-physicochemical-and-functional-properties-and-in-vitro-fecal-fermentation-characteristics-of-barley-dietary-fiber-fermented-by-lactiplantibacillus-plantarum-dy-1
#3
JOURNAL ARTICLE
Xiang Xiao, Xiaodong Li, Juan Bai, Songtao Fan, Maria Daglia, Jiaying Li, Yiwei Ding, Yanshun Zhang, Yansheng Zhao
Fermentation is an effective method for improving the nutritional quality and functional characteristics of grains. This study investigated changes in the structural, physicochemical, and functional properties of fermented barley dietary fiber (FBDF) exerted by Lactiplantibacillus plantarum dy-1 ( Lp. plantarum dy-1) as well as its in vitro fecal fermentation characteristics. Lp. plantarum dy-1 fermentation remarkably changed the structure of FBDF, including the microstructure and monosaccharide components, correlating with improved water or oil retaining and cholesterol adsorption capacities...
March 25, 2024: Food & Function
https://read.qxmd.com/read/38524237/detection-of-typical-indigenous-gut-bacteria-related-to-kanpyo-lagenaria-siceraria-var-hispida-powder-in-murine-caecum-and-human-faecal-cultures
#4
JOURNAL ARTICLE
Mahiro Yamamoto, Hikaru Ogura, Takashi Kuda, Yumeng Xia, Ayaka Nakamura, Hajime Takahashi, Junji Inoue, Shu Takayanagi
Kanpyo (KP) is an edible dried product produced by peeling the fruit of the gourd Lagenaria siceraria var . hispida ; it is used in the traditional Japanese cuisine. The health functionality of KP due to its rich dietary fibre is expected to include a possible combined effect of KP-responsive indigenous gut bacteria (KP-RIB). However, its effect on the gut microbiota is unclear. To determine the effects of the KP on the gut microbiota and their host, Institute of Cancer Research mice were fed a high-sucrose diet containing no fibre (NF) or 5% (w/w) KP for 14 days, and their caecal microbiota was analysed by 16S rRNA (V4) amplicon sequencing...
April 2024: 3 Biotech
https://read.qxmd.com/read/38521425/digestive-characteristics-of-gastrodia-elata-blume-polysaccharide-and-related-impacts-on-human-gut-microbiota-in-vitro
#5
JOURNAL ARTICLE
Qingxia Gan, Linlin Chen, Jiacheng Xian, Guangqin An, Haobo Wei, Yuntong Ma
ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Blume is a traditional Chinese medicine with the effects of improving the deficiency of the body and maintaining health, and polysaccharide (GEP) is one of the effective ingredients to play these activities of G. elata. Traditionally, G. elata is orally administered, so the activities of GEP are associated with digestive and intestinal metabolism. However, the digestive behavior of GEP and its effects on the human gut microbiota are unclear and need to be fully studied...
March 21, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38519184/food-additives-impair-gut-microbiota-from-healthy-individuals-and-ibd-patients-in-a-colonic-in-vitro-fermentation-model
#6
JOURNAL ARTICLE
Irma Gonza, Elizabeth Goya-Jorge, Caroline Douny, Samiha Boutaleb, Bernard Taminiau, Georges Daube, Marie-Louise Scippo, Edouard Louis, VĂ©ronique Delcenserie
Intestinal fibrosis is a long-term complication of inflammatory bowel diseases (IBD). Changes in microbial populations have been linked with the onset of fibrosis and some food additives are known to promote intestinal inflammation facilitating fibrosis induction. In this study, we investigated how polysorbate 80, sucralose, titanium dioxide, sodium nitrite and maltodextrin affect the gut microbiota and the metabolic activity in healthy and IBD donors (patients in remission and with a flare of IBD). The Simulator of the Human Intestinal Microbial Ecosystem (SHIME®) with a static (batch) configuration was used to evaluate the effects of food additives on the human intestinal microbiota...
April 2024: Food Research International
https://read.qxmd.com/read/38517129/associations-between-health-behaviors-gastrointestinal-symptoms-and-gut-microbiota-in-a-cross-sectional-sample-of-cancer-survivors-secondary-analysis-from-the-chemo-gut-study
#7
JOURNAL ARTICLE
Julie M Deleemans, Faye Chleilat, Raylene A Reimer, Oluwaseyi A Lawal, Mohamad Baydoun, Katherine-Ann Piedalue, Dana E Lowry, Linda E Carlson
BACKGROUND: Health behaviors, such as diet and exercise, are actions individuals take that can potentially impact gastrointestinal (GI) symptoms and the gut microbiota. Little is known about how health behaviors impact GI symptoms and the gut microbiota after anti-cancer therapies. METHODS: This is a secondary analysis of a cross-sectional study that investigated relationships between GI symptoms, gut microbiota, and patient-reported outcomes in adult cancer survivors...
2024: Integrative Cancer Therapies
https://read.qxmd.com/read/38516317/functional-contribution-of-the-intestinal-microbiome-in-autism-spectrum-disorder-attention-deficit-hyperactivity-disorder-and-rett-syndrome-a-systematic-review-of-pediatric-and-adult-studies
#8
Valentina Caputi, Lee Hill, Melanie Figueiredo, Jelena Popov, Emily Hartung, Kara Gross Margolis, Kanish Baskaran, Papiha Joharapurkar, Michal Moshkovich, Nikhil Pai
INTRODUCTION: Critical phases of neurodevelopment and gut microbiota diversification occur in early life and both processes are impacted by genetic and environmental factors. Recent studies have shown the presence of gut microbiota alterations in neurodevelopmental disorders. Here we performed a systematic review of alterations of the intestinal microbiota composition and function in pediatric and adult patients affected by autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and Rett syndrome (RETT)...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38508355/toxicity-of-three-microcystin-variants-on-the-histology-physiological-and-metabolism-of-hepatopancreas-and-intestinal-microbiota-of-litopenaeus-vannamei
#9
JOURNAL ARTICLE
Yafei Duan, Yuxiu Nan, Meng Xiao, Yukai Yang
Microcystins (MCs) are prevalent harmful contaminants within shrimp aquaculture systems, exhibiting a diverse array of variants. Gut microbiota can engage in mutual interactions with the host through the gut-liver axis. In this study, the shrimp Litopenaeus vannamei were subjected to three different variants of MCs (LR, YR, RR) at a concentration of 1 μg/L each, and elucidated the alterations in both intestinal microbiota and hepatopancreas physiological homeostasis. The results indicate that all three variants of MCs prompted histological alterations in the hepatopancreas, induced elevated levels of oxidative stress biomarkers (H2 O2 , SOD, and CAT), disturbed the transcription levels of immune-related genes (Crus, ALF, and Lys), along with an increase in apoptotic genes (Casp-3 and P53)...
March 18, 2024: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://read.qxmd.com/read/38508114/comparative-analysis-of-chlorine-resistant-bacteria-after-chlorination-and-chloramination-in-drinking-water-treatment-plants
#10
JOURNAL ARTICLE
Yijun Wei, Haiyan Wu, Xudong Zhang, Yongbing Liang, Danyang Shi, Lin Wang, Haibei Li, Hongling Yu, Dong Yang, Shuqing Zhou, Tianjiao Chen, Zhongwei Yang, Junwen Li, Min Jin
Chlorine-resistant bacteria (CRB) in drinking water treatment plants (DWTPs) jeopardize water quality and pose a potential risk to human health. However, the specific response of CRB to chlorination and chloramination remains uncharacterized. Therefore, we analyzed 16 S rRNA sequencing data from water samples before and after chlorination and chloramination taken between January and December 2020. Proteobacteria and Firmicutes dominated all finished water samples. After chloramination, Acinetobacter, Pseudomonas, Methylobacterium, Ralstonia, and Sphingomonas were the dominant CRB, whereas Ralstonia, Bacillus, Acinetobacter, Pseudomonas, and Enterococcus were prevalent after chlorination...
March 18, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38502145/-bacteroides-thetaiotaomicron-and-faecalibacterium-prausnitzii-served-as-key-components-of-fecal-microbiota-transplantation-to-alleviate-colitis
#11
JOURNAL ARTICLE
Binqiang Xu, Yang Fu, Nuoming Yin, Wenfei Qin, Zehua Huang, Wei Xiao, Huizhen Huang, Qixiang Mei, Junjie Fan, Yue Zeng, Chunlan Huang
Fecal microbiota transplantation (FMT) is a promising therapy for inflammatory bowel disease (IBD) via rectifying gut microbiota. The aim of this study was to identify a mechanism of how specific bacteria-associated immune response contributes to alleviated colitis. 40 donors were divided into high (donor-H) and low (donor-L) groups according to diversity and the abundance of Bacteroides and Faecalibacterium by 16S rRNA sequencing. FMT was performed on dextran sulfate sodium (DSS)-induced colitis in mice. Mice with colitis showed significant improvement in intestinal injury and immune imbalance after FMT with group donor-H ( p <0...
March 19, 2024: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://read.qxmd.com/read/38497712/alterations-of-intestinal-mucosal-barrier-cecal-microbiota-diversity-composition-and-metabolites-of-yellow-feathered-broilers-under-chronic-corticosterone-induced-stress-a-possible-mechanism-underlying-the-anti-growth-performance-and-glycolipid-metabolism-disorder
#12
JOURNAL ARTICLE
Fei Li, Xinyu Chen, Xingyu Xu, Lijun Wang, Jie Yan, Yichen Yu, Xuemei Shan, Rui Zhang, Hua Xing, Tangjie Zhang, Shifeng Pan
UNLABELLED: This study aimed to explore alterations in growth performance, glycolipid metabolism disorders, intestinal mucosal barrier, cecal microbiota community, and metabolites in a chronic corticosterone (CORT)-induced stress (CCIS) broiler model. Results showed that compared with control (CON) broilers, in CCIS broilers: (i) the final body weight (BW), BW gain, and average daily gain were significantly reduced. (ii) The glycolipid metabolism disorder and impairement of intestinal immune barrier and physical barrier function were observed...
March 18, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38497338/therapeutic-strategies-to-modulate-gut-microbial-health-approaches-for-sarcopenia-management
#13
REVIEW
Shreya Das, B Preethi, Sapana Kushwaha, Richa Shrivastava
Sarcopenia is a progressive and generalized loss of skeletal muscle and functions associated with ageing with currently no definitive treatment. Alterations in gut microbial composition have emerged as a significant contributor to the pathophysiology of multiple diseases. Recently, its association with muscle health has pointed to its potential role in mediating sarcopenia. The current review focuses on the association of gut microbiota and mediators of muscle health, connecting the dots between the influence of gut microbiota and their metabolites on biomarkers of sarcopenia...
March 6, 2024: Histology and Histopathology
https://read.qxmd.com/read/38495337/double-blinded-randomized-clinical-trial-of-gegen-qinlian-decoction-pinpoints-faecalibacterium-as-key-gut-bacteria-in-alleviating-hyperglycemia
#14
Zezheng Gao, Wenhui Zhang, Lisha He, Han Wang, Yufei Li, Xiaotian Jiang, Sha D I, Xinmiao Wang, Xuan Zhang, Lin Han, Yanwen Liu, Chengjuan Gu, Mengyi Wu, Xinhui He, Lei Cheng, Jun Wang, Xiaolin Tong, Linhua Zhao
BACKGROUND: Accumulating evidence suggests that metabolic disorders, including type 2 diabetes mellitus (T2DM), can be treated with traditional Chinese medicine formulas, such as the Gegen Qinlian decoction (GQD). This study elucidates the mechanisms by which gut microbes mediate the anti-diabetic effects of GQD. METHODS: We conducted a double-blind randomized clinical trial involving 120 untreated participants with T2DM. During the 12-week intervention, anthropometric measurements and diabetic traits were recorded every 4 weeks...
March 2024: Precision Clinical Medicine
https://read.qxmd.com/read/38493690/dupilumab-therapy-improves-gut-microbiome-dysbiosis-and-tryptophan-metabolism-in-chinese-patients-with-atopic-dermatitis
#15
JOURNAL ARTICLE
Liu Yang, Danqi Li, Shuomin Sun, Danping Liu, Yi Wang, Xiaohuan Liu, Bin Zhou, Wenjia Nie, Lu Li, Yifei Wang, Shanshan Sha, Yan Li, Chen Shen, Juan Tao
BACKGROUND: Dupilumab has demonstrate its potential to orchestrate inflammatory skin microenvironment, enhance skin barrier and shift skin microbiome dysbiosis, collectively contributing to clinical improvement in patients with atopic dermatitis (AD). As the second genome of human body, growing evidence suggests that the gut microbiome might relate to the host response to treatments. Little is known about the association between dupilumab treatment and gut microbiome in AD patients. OBJECTIVE: We aimed to characterize the gut microbiome among Chinese subjects with or without AD and determine the potential effect of dupilumab on the gut microbiome...
March 16, 2024: International Immunopharmacology
https://read.qxmd.com/read/38480544/postbiotic-butyrate-role-and-its-effects-for-being-a-potential-drug-and-biomarker-to-pancreatic-cancer
#16
REVIEW
Abinaya Elango, Vineeta Debbie Nesam, Padmaja Sukumar, Infancia Lawrence, Arunkumar Radhakrishnan
Postbiotics are produced by microbes and have recently gained importance in the field of oncology due to their beneficial effects to the host, effectiveness against cancer cells, and their ability to suppress inflammation. In particular, butyrate dominates over all other postbiotics both in quantity and anticancer properties. Pancreatic cancer (PC), being one of the most malignant and lethal cancers, reported a decreased 5-year survival rate in less than 10% of the patients. PC causes an increased mortality rate due to its inability to be detected at an early stage but still a promising strategy for its diagnosis has not been achieved yet...
March 13, 2024: Archives of Microbiology
https://read.qxmd.com/read/38471895/-air-microbial-contamination-and-risk-of-respiratory-exposure-of-workers-in-chicken-farms
#17
JOURNAL ARTICLE
Yu-Qiao Bai, Xing-Bin Sun, Tian-Lei Qiu, Ya-Jie Guo, Min Gao, Xu-Ming Wang
Animal farms are important sources of microbial contamination in the air environment. However, there are few reports on the time-regularity characteristics of airborne microbial contamination in farms. In the context of this situation, a study was conducted for more than 80 weeks using 16S rRNA gene amplicon sequencing to characterize the bacterial distribution and respiratory exposure in the farm air and fecal environment, respectively, taking a layer farm as an example. The results showed that 16S rRNA concentrations in air and manure samples ranged from 6...
March 8, 2024: Huan Jing Ke Xue= Huanjing Kexue
https://read.qxmd.com/read/38468206/metagenomic-gut-microbiome-analysis-of-japanese-patients-with-multiple-chemical-sensitivity-idiopathic-environmental-intolerance
#18
JOURNAL ARTICLE
Kentaro Watai, Wataru Suda, Rina Kurokawa, Kiyoshi Sekiya, Hiroaki Hayashi, Maki Iwata, Kisako Nagayama, Yuto Nakamura, Yuto Hamada, Yosuke Kamide, Yuma Fukutomi, Takeru Nakabayashi, Kosei Tanaka, Masahiro Kamita, Masami Taniguchi, Masahira Hattori
BACKGROUND: Although the pathology of multiple chemical sensitivity (MCS) is unknown, the central nervous system is reportedly involved. The gut microbiota is important in modifying central nervous system diseases. However, the relationship between the gut microbiota and MCS remains unclear. This study aimed to identify gut microbiota variations associated with MCS using shotgun metagenomic sequencing of fecal samples. METHODS: We prospectively recruited 30 consecutive Japanese female patients with MCS and analyzed their gut microbiomes using shotgun metagenomic sequencing...
March 11, 2024: BMC Microbiology
https://read.qxmd.com/read/38465231/placebo-resistant-gut-bacteria-akkermansia-muciniphila-spp-and-familial-mediterranean-fever-disease
#19
JOURNAL ARTICLE
Elya Pepoyan, Francesco Marotta, Anahit Manvelyan, Artak Galstyan, Lena Stepanyan, Hasmik Grigoryan, Liana Grigoryan, Mikayel Mikayelyan, Marine Balayan, Natalya Harutyunyan, Susanna Mirzabekyan, Vardan Tsaturyan, Tamas Torok, Astghik Pepoyan
INTRODUCTION: Despite numerous investigations into the impact of drugs/probiotics on the gut microbiota composition in Familial Mediterranean Fever (FMF) patients, the question as to whether there exists a significant bacterial diversity(ies) independent of the placebo effect that can be reliably considered in clinical and nutritional trials remains unresolved. METHODS: This study represents the in augural analysis of the placebo's influence on the gut microbiota of both healthy individuals and FMF afflicted men, utilizing previously collected data from PhyloChip™ DNA microarray experiments...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38456962/association-between-altered-microbiota-composition-and-immune-system-related-genes-in-covid-19-infection
#20
JOURNAL ARTICLE
Sara Ahmadi Badi, Arian Kariman, Ahmad Bereimipour, Shima Shojaie, Mohammadreza Aghsadeghi, Shohreh Khatami, Andrea Masotti
Microbiota and immunity affect the host's susceptibility to SARS-CoV-2 infection and the severity of COVID-19. This study aimed to identify significant alterations in the microbiota composition, immune signaling pathways, their potential association, and candidate microRNA in COVID-19 patients using an in silico study model. Enrichment online databases and Python programming were utilized to analyze GSE164805, GSE180594, and GSE182279, as well as NGS data of microbiota composition (PRJNA650244 and PRJNA660302) associated with COVID-19, employing amplicon-based/marker gene sequencing methods...
March 8, 2024: Molecular Biotechnology
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