keyword
https://read.qxmd.com/read/38535970/easy-to-implement-educational-interventions-to-bring-climate-smart-actions-to-daily-anesthesiologic-practice-a-cross-sectional-before-and-after-study
#1
JOURNAL ARTICLE
Theresa Dölker, Julia Schuler, Julia Wallqvist, Rolf Rossaint, Ana Kowark, Sebastian Ziemann, Frederick Schneider, Adrian A Baumann, Neal Conway, Linda GRÜßER
BACKGROUND: Anesthesia contributes significantly to a hospital's carbon footprint. Climate-smart actions have the potential to reduce greenhouse gas emissions. Prerequisites for sustainable behavior of providers are knowledge and awareness. We aimed to assess the change in anesthesiologists' climate-friendly behavior before and after educational interventions in three areas that every anesthesiologist can address in their daily clinical routine: 1) energy use; 2) recycling opportunities; 3) consumption of volatile anesthetics...
March 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38521500/comparison-of-terbutaline-and-atosiban-as-tocolytic-agents-in-intrauterine-repair-of-myelomeningocele-a-retrospective-cohort-study
#2
JOURNAL ARTICLE
Shirley Andrade Santos, Fernando Souza Nani, Elaine Imaeda de Moura, Diogo Lima de Carvalho, Guilherme Jorge Mattos Miguel, Cristiane Maria Federicci Haddad, Joaquim Edson Vieira, Victor Bunduki, Mário Henrique Burlacchini de Carvalho, Rossana Pulcineli Vieira Francisco, Daniel Dante Cardeal, Hermann Dos Santos Fernandes
BACKGROUND: Myelomeningocele (MMC) is a neural tube defect disease. Antenatal repair of fetal MMC is an alternative to postnatal repair. Many agents can be used as tocolytics during the in utero fetal repair such as β2-agonists and oxytocin receptor antagonists, with possible maternal and fetal repercussions. This study aims to compare maternal arterial blood gas analysis between terbutaline or atosiban, as tocolytic agents, during intrauterine MMC repair. METHODS: Retrospective cohort study...
March 21, 2024: Brazilian Journal of Anesthesiology
https://read.qxmd.com/read/38468514/altitude-effect-on-propofol-pharmacokinetics-in-rats
#3
JOURNAL ARTICLE
Lijun Li, Xuejun Wang, Sheng Wang, Li Wen, Haopeng Zhang
BACKGROUND: Propofol is an intravenous agent for clinical anesthesia. As the influence of the hypobaric- hypoxic environment (Qinghai-Tibetan region, altitude: 2800-4300 m, PaO2: 15.1-12.4 kPa) on the metabolism of Propofol is complex, the research results on the metabolic characteristics of Propofol in high-altitude areas remain unclear. This study aimed to investigate the pharmacokinetic characteristics of Propofol in a high-altitude hypoxic environment using animal experiments. METHODS: Rats were randomly divided into three groups: high-altitude, medium-altitude, and plain groups...
March 11, 2024: Current Drug Metabolism
https://read.qxmd.com/read/38461172/regional-pulmonary-perfusion-blood-volume-and-their-relationship-change-in-experimental-early-ards
#4
JOURNAL ARTICLE
Arnoldo Santos, Gabriel C Motta-Ribeiro, Nicolas de Prost, Mauro R Tucci, Tyler J Wellman, Marcos F Vidal Melo, Tilo Winkler
Regional pulmonary perfusion (Q) has been investigated using blood volume (Fb ) imaging as an easier-to-measure surrogate. However, it is unclear if changing pulmonary conditions could affect their relationship. We hypothesized that vascular changes in early acute respiratory distress syndrome (ARDS) affect Q and Fb differently. Five sheep were anesthetized and received lung protective mechanical ventilation for 20 h while endotoxin was continuously infused. Using dynamic 18 F-FDG and 13 NN Positron Emission Tomography (PET), regional Fb and Q were analysed in 30 regions of interest (ROIs) and normalized by tissue content (Fbn and Qn , respectively)...
March 10, 2024: Scientific Reports
https://read.qxmd.com/read/38452428/effect-of-a-non-reactive-absorbent-with-or-without-environmentally-oriented-electronic-feedback-on-anesthesia-provider-s-fresh-gas-flow-rates-a-greening-initiative
#5
JOURNAL ARTICLE
Carlos E Guerra-Londono, Franklin Dexter, John D Mitchell, Patrick B Forrest, Donald H Penning
STUDY OBJECTIVE: To examine the effects of a non-reactive carbon dioxide absorbent (AMSORB® Plus) versus a traditional carbon dioxide absorbent (Medisorb™) on the FGF used by anesthesia providers and an electronic educational feedback intervention using Carestation™ Insights (GE HealthCare) on provider-specific change in FGF. DESIGN: Prospective, single-center cohort study set in a greening initiative. SETTING: Operating room...
March 6, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38444936/attenuation-of-intestinal-ischemia-reperfusion-injury-by-anesthetics-a-potentially-protective-effect-of-anesthetic-management-in-experimental-studies
#6
REVIEW
Zhan Huang, Yiping Bai, Ying Chen, Ye Chen, Yuan Jiang, Jun Zhou
Intestinal ischemia-reperfusion injury (IRI) is a potentially severe clinical syndrome after major surgical procedures. In addition to causing intestinal mucosa injury, intestinal IRI further damages distant organs, causing the severity of the condition in patients. So far, effective therapy for intestinal IRI is still absent, and the survival rate of the patients is low. Previous experimental studies have shown that some anesthetics can alleviate intestinal IRI and protect organs while exerting their pharmacological effects, indicating that reasonable perioperative anesthesia management may provide potential benefits for patients to avoid intestinal IRI...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38444563/predicting-the-climate-impact-of-healthcare-facilities-using-gradient-boosting-machines
#7
JOURNAL ARTICLE
Hao Yin, Bhavna Sharma, Howard Hu, Fei Liu, Mehak Kaur, Gary Cohen, Rob McConnell, Sandrah P Eckel
Health care accounts for 9-10% of greenhouse gas (GHG) emissions in the United States. Strategies for monitoring these emissions at the hospital level are needed to decarbonize the sector. However, data collection to estimate emissions is challenging, especially for smaller hospitals. We explored the potential of gradient boosting machines (GBM) to impute missing data on resource consumption in the 2020 survey of a consortium of 283 hospitals participating in Practice Greenhealth. GBM imputed missing values for selected variables in order to predict electricity use and beef consumption (R2 =0...
March 2024: Clean Environ Syst
https://read.qxmd.com/read/38437201/mousepzt-a-simple-reliable-low-cost-device-for-vital-sign-monitoring-and-respiratory-gating-in-mice-under-anesthesia
#8
JOURNAL ARTICLE
Daniel A Rivera, Anne E Buglione, Sadie E Ray, Chris B Schaffer
Small animal studies in biomedical research often require anesthesia to reduce pain or stress experienced by research animals and to minimize motion artifact during imaging or other measurements. Anesthetized animals must be closely monitored for the safety of the animals and to prevent unintended effects of altered physiology on experimental outcomes. Many currently available monitoring devices are expensive, invasive, or interfere with experimental design. Here, we present MousePZT, a low-cost device based on a simple piezoelectric sensor, with a custom circuit and computer software that allows for measurements of both respiratory rate and heart rate in a non-invasive, minimal contact manner...
2024: PloS One
https://read.qxmd.com/read/38433171/minimum-anesthetic-concentration-of-isoflurane-and-sevoflurane-and-cardiorespiratory-effects-of-varying-inspired-oxygen-fractions-in-magellanic-penguins-spheniscus-magellanicus
#9
JOURNAL ARTICLE
André Nicolai Elias da Silva, Gustavo Henrique Pereira Dutra, André Augusto Justo, Giuliano Souza Mendonça de Araujo, Thais Feres Bressan, Adriano Bonfim Carregaro
The aim of this study was to determine the minimum anesthetic concentration of isoflurane (MACISO ) and sevoflurane (MACSEVO ) and evaluate the cardiorespiratory changes induced by varying fractions of inspired oxygen (FiO2 ) in Magellanic penguins (Spheniscus magellanicus). Twenty adult penguins (3.53 ± 0.44 kg) of undetermined sex were used. Both MACISO (n = 9) and MACSEVO (n = 13) were established using an up-and-down design. Next, twelve mechanically ventilated penguins were maintained at 1 MACISO or 1 MACSEVO (n = 6 per group) with the FiO2 initially set at 1...
March 4, 2024: Veterinary Research Communications
https://read.qxmd.com/read/38428851/reducing-the-carbon-footprint-of-operating-rooms-through-education-on-the-effects-of-inhalation-anesthetics-on-global-warming-a-retrospective-study
#10
JOURNAL ARTICLE
Eun Ji Park, Jaesang Bae, Jisu Kim, Ji-Uk Yoon, Wangseok Do, Jung-Pil Yoon, Hong-Sik Shon, Yerin Kang, Hee Young Kim, Ah-Reum Cho
Environmental concerns, especially global warming, have prompted efforts to reduce greenhouse gas emissions. Healthcare systems, including anesthesia practices, contribute to these emissions. Inhalation anesthetics have a significant environmental impact, with desflurane being the most concerning because of its high global warming potential. This study aimed to educate anesthesiologists on the environmental impact of inhalation anesthetics and assess changes in awareness and practice patterns, specifically reducing desflurane use...
March 1, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38420682/benefits-of-intratracheal-and-extrathoracic-high-frequency-percussive-ventilation-in-a-model-of-capnoperitoneum
#11
JOURNAL ARTICLE
Ferenc Peták, Roberta Südy, John Diaper, Fabienne Fontao, Davide Bizzotto, Raffaele L Dellacà, Walid Habre, Álmos Schranc
Abdominal inflation with CO2 is used to facilitate laparoscopic surgeries, however providing adequate mechanical ventilation in this scenario is of major importance during anesthesia management. We characterized high frequency percussive ventilation (HFPV) in protecting from the gas exchange and respiratory mechanical impairments during capnoperitoneum. In addition, we aimed to assess the difference between conventional pressure-controlled mechanical ventilation (CMV) and HFPV modalities generating the high-frequency signal intratracheally (HFPVi) or extrathoracally (HFPVe)...
February 29, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38420678/a-novel-method-for-tracking-hyperbaric-nitrogen-kinetics-in-vivo-using-radioactive-nitrogen-13-gas-and-positron-emission-tomography
#12
JOURNAL ARTICLE
Edward T Ashworth, Ryotaro Ogawa, Juliana Nguyen, Chloe Afif, Rui C Sá, Kim Butts Pauly, David R Vera, Peter Lindholm
Decompression sickness (DCS) is caused by gaseous nitrogen dissolved in tissues forming bubbles during decompression. To date no method exists to identify nitrogen within tissues, but with advances in PET technology it may be possible to track gaseous radionuclides into tissues. We aimed to develop a method to track nitrogen movement in vivo that could then be used to further our understanding of DCS using nitrogen-13 (13 N2 ). A single anesthetized female Sprague Dawley rat, was exposed to 625 kPa, composed of air, isoflurane and 13 N2 for 10 min...
February 29, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38419616/femoral-nailing-in-a-porcine-model-causes-bone-marrow-emboli-in-the-lungs-and-systemic-emboli-in-the-heart-and-brain
#13
JOURNAL ARTICLE
Steinar Kristiansen, Anders Hagen Jarmund, Jonas Hilmo, Tom Eirik Mollnes, Martin Leth-Olsen, Siri Ann Nyrnes, Bent Aksel Nilsen, Renathe Henriksen Grønli, Bjørn Ove Faldaas, Benjamin Storm, Arild Espenes, Erik Waage Nielsen
BACKGROUND: Shaft fractures of the femur are commonly treated with intramedullary nailing, which can release bone marrow emboli into the bloodstream. Emboli can travel to the lungs, impairing gas exchange and causing inflammation. Occasionally, emboli traverse from the pulmonary to the systemic circulation, hindering perfusion and resulting in injuries such as heart and brain infarctions, known as fat embolism syndrome . We studied the extent of systemic bone marrow embolization in a pig model...
2024: JB & JS Open Access
https://read.qxmd.com/read/38416820/mapping-cerebral-perfusion-in-mice-under-various-anesthesia-levels-using-highly-sensitive-bold-mri-with-transient-hypoxia
#14
JOURNAL ARTICLE
Thuy Thi Le, Geun Ho Im, Chan Hee Lee, Sang Han Choi, Seong-Gi Kim
Cerebral perfusion is critical for the early detection of neurological diseases and for effectively monitoring disease progression and treatment responses. Mouse models are widely used in brain research, often under anesthesia, which can affect vascular physiology. However, the impact of anesthesia on regional cerebral blood volume and flow in mice has not been thoroughly investigated. In this study, we have developed a whole-brain perfusion MRI approach by using a 5-second nitrogen gas stimulus under inhalational anesthetics to induce transient BOLD dynamic susceptibility contrast (DSC)...
March 2024: Science Advances
https://read.qxmd.com/read/38405258/physiological-and-anesthetic-considerations-of-safe-and-optimal-pneumoperitoneal-pressures-for-laparoscopic-surgeries-in-children
#15
JOURNAL ARTICLE
Preeti Joon, Ankur Mandelia, Sanjay Dhiraaj, Tapas Kumar Singh, Chetna Shamshery, Prabhaker Mishra
CONTEXT: In the era of minimally invasive surgeries, pediatric laparoscopic surgeries are now becoming the standard of care. AIM: In this study, we aim to determine the safe and optimal pneumoperitoneal pressures (PPs) for laparoscopic surgery in children aged 1-5 years, along with the technical ease for the surgeon. SETTINGS AND DESIGN: Prospective, randomized, single-blinded study was conducted at SGPGI Lucknow. MATERIALS AND METHODS: Children aged 1-5 years were randomized into Group I ( n = 24): PP = 6-8 mmHg and Group II: (PP) = 9-10 mmHg...
2024: Journal of Indian Association of Pediatric Surgeons
https://read.qxmd.com/read/38402051/explanatory-factors-for-the-use-of-local-anesthetics-in-the-management-of-pain-induced-by-arterial-puncture-for-blood-gas-analysis-by-nurses
#16
Julio Alberto Mateos-Arroyo, Ignacio Zaragoza-García, Rubén Sánchez-Gómez, Paloma Posada-Moreno, Sara García-Almazán, Ismael Ortuño-Soriano
No abstract text is available yet for this article.
February 13, 2024: Archivos de Bronconeumología
https://read.qxmd.com/read/38395800/molecular-hydrogen-attenuates-sepsis-induced-cardiomyopathy-in-mice-by-promoting-autophagy
#17
JOURNAL ARTICLE
Yan Cui, Yingning Li, Shuqi Meng, Yu Song, Keliang Xie
BACKGROUND: Approximately 40 to 60% of patients with sepsis develop sepsis-induced cardiomyopathy (SIC), which is associated with a substantial increase in mortality. We have found that molecular hydrogen (H2 ) inhalation improved the survival rate and cardiac injury in septic mice. However, the mechanism remains unclear. This study aimed to explore the regulatory mechanism by which hydrogen modulates autophagy and its role in hydrogen protection of SIC. METHODS: Cecal ligation and puncture (CLP) was used to induce sepsis in adult C57BL/6J male mice...
February 23, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38390936/anesthesia-for-gender-affirming-surgery-a-practical-review
#18
JOURNAL ARTICLE
Kyle Sanchez, Luis Tollinche, Travis Reece-Nguyen
PURPOSE OF REVIEW: Gender-affirming surgery (GAS) is an effective, well studied, and often necessary component of gender-affirming care and mitigation of gender dysphoria for transgender and gender-diverse (TGD) individuals. GAS is categorized as chest surgeries, genitourinary surgeries, facial feminization/masculinization, and vocal phonosurgery. Despite increased incidence of GAS during recent years, there is a gap in knowledge and training on perioperative care for TGD patients. RECENT FINDINGS: Our review discusses the relevant anesthetic considerations for the most common GAS, which often involve highly specialized surgical techniques that have unique implications for the anesthesia professional...
February 22, 2024: Current Opinion in Anaesthesiology
https://read.qxmd.com/read/38390390/xenon-ameliorates-chronic-post-surgical-pain-by-regulating-mitophagy-in-microglia-and-rats-mediated-by-pink1-parkin-pathway
#19
JOURNAL ARTICLE
Hu Lv, Jiaojiao Huang, Xin Zhang, Zhiyong He, Jun Zhang, Wei Chen
BACKGROUND: Chronic post-surgical pain (CPSP) is one of the important causes of poor postoperative outcomes, the activation of microglia in the spinal cord is closely related to the generation, transmission and maintenance of CPSP. Xenon (Xe), an anesthetic gas, has been reported to be able to significantly reduce intraoperative analgesia and postoperative pain sensation at low doses. However, the mechanism of the regulatory effect of xenon on activated microglia after CPSP remains unclear...
2024: PeerJ
https://read.qxmd.com/read/38389970/stability-study-and-development-of-the-validated-infrared-spectrometric-method-for-quantitative-analysis-of-sevoflurane-compared-with-the-gas-chromatographic-method
#20
JOURNAL ARTICLE
Kahtan Jassim Hasson
Sevoflurane, also called fluoromethyl ether, is an inhalation anesthetic agent used to initiate and maintain general anesthesia for adults and pediatric patients during surgical procedures. Several analytical methods have previously been applied to follow the properties and quality of sevoflurane, including mass spectrometry and gas chromatography methods. These methods are practically tedious and need sophisticated apparatus. In the present work, an attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectrometric method was used for the quantitative determination of sevoflurane which is characterized as a fast, accurate, and available technique for most pharmaceutical laboratories, besides the gas chromatographic method which is the most suitable for the detection of impurities...
2024: Journal of Advanced Pharmaceutical Technology & Research
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