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Takahisa Kawaguchi, Toshihide Shima, Masayuki Mizuno, Yasuhide Mitsumoto, Atsushi Umemura, Yoshihiro Kanbara, Saiyu Tanaka, Yoshio Sumida, Kohichiro Yasui, Meiko Takahashi, Keitaro Matsuo, Yoshito Itoh, Katsutoshi Tokushige, Etsuko Hashimoto, Kendo Kiyosawa, Masanori Kawaguchi, Hiroyuki Itoh, Hirofumi Uto, Yasuji Komorizono, Ken Shirabe, Shiro Takami, Toshinari Takamura, Miwa Kawanaka, Ryo Yamada, Fumihiko Matsuda, Takeshi Okanoue
The genetic factors affecting the natural history of nonalcoholic fatty liver disease (NAFLD), including the development of nonalcoholic steatohepatitis (NASH) and NASH-derived hepatocellular carcinoma (NASH-HCC), are still unknown. In the current study, we sought to identify genetic factors related to the development of NAFLD, NASH, and NASH-HCC, and to establish risk-estimation models for them. For these purposes, 936 histologically proven NAFLD patients were recruited, and genome-wide association (GWA) studies were conducted for 902, including 476 NASH and 58 NASH-HCC patients, against 7,672 general-population controls...
2018: PloS One
Kendo Mori, Na Renhu, Maho Naito, Aki Nakamura, Hayato Shiba, Tsuyoshi Yamamoto, Takuya Suzaki, Hidetoshi Iida, Kenji Miura
Cold shock triggers an immediate rise in the cytosolic free calcium concentration ([Ca2+ ]cyt ) in Arabidopsis thaliana and this cold-induced elevation of [Ca2+ ]cyt is inhibited by lanthanum or EGTA. It is suggested that intracellular calcium mainly contributes to the cold-induced [Ca2+ ]cyt response by entering into the cytosol. Two calcium-permeable mechanosensitive channels, MCA1 and MCA2 (mid1-complementing activity), have been identified in Arabidopsis. Here, we demonstrate that MCA1 and MCA2 are involved in a cold-induced increase in [Ca2+ ]cyt ...
January 11, 2018: Scientific Reports
Dário Lucas Costa de Mendonça, Angelica Castilho Alonso, Júlia Maria D'Andrea Greve, Luiz Eugênio Garcez-Leme
OBJECTIVE: To compare Kendo players with active elderly adults in terms of quality of life, functional aspects (muscle strength, postural balance) and body composition. METHODS: This was a controlled cross-sectional study. Twenty elderly individuals were divided into two groups: the Kendo group, with an average age of 71.8 (5.4) years, and the Control group, with an average age of 73.1 (4.8) years. Quality of life was evaluated using a questionnaire (WHOQOL-bref and WHOQOL-old); body composition was evaluated with a bioimpedance scale (InBody230); hand-grip strength was assessed with a portable manual dynamometer (Jamar SH 5001); flexor and extensor muscle strength of the knees was evaluated with an isokinetic device (Biode® System 3 model Biodex Multi Joint System, BIODEX); and dynamic balance was assessed using a force platform (Balance Master System, Neurocom International, Inc...
November 2017: Clinics
Ayumi Sugiura, Shuichi Wada, Hiromitsu Mori, Takefumi Kimura, Yoshiaki Matsuda, Naoki Tanaka, Eiji Tanaka, Kendo Kiyosawa
Persistent hepatitis C virus (HCV) infection may induce autoimmune diseases and chronic hepatitis C is sometimes accompanied by autoimmune hepatitis (AIH). However, we are worried about the treatment for chronic hepatitis C-AIH overlap syndrome because interferon-based antiviral therapies may enhance autoimmunity and immunosuppressive corticosteroid administration may promote viral replication. Here, we report a patient having chronic hepatitis C-AIH overlap syndrome treated with the direct-acting antivirals (DAA), daclatasvir and asunaprevir...
May 2017: Case Reports in Gastroenterology
Shinya Kishi, Munehito Yoshida
[Purpose] Elbow injury in male adult kendo players was investigated and examined in order to obtain an indicator of prophylaxis of injury. [Subjects and Methods] The subjects were 22 male adult kendo players aged 25 to 60 years old, and presence or absence of pain, range of motion, and muscle strength in the elbow joints were investigated. In addition, among athletes with limited range of motion (ROM) in the elbow joints, three athletes who had received an explanation and had provided informed consent underwent CT, and the images were examined...
March 2017: Journal of Physical Therapy Science
Masafumi Maruyama, Naoki Tanaka, Daisuke Kubota, Masayuki Miyajima, Takefumi Kimura, Koujiro Tokutake, Ryujiro Imai, Toru Fujisawa, Hiromitsu Mori, Yoshiaki Matsuda, Shuichi Wada, Akira Horiuchi, Kendo Kiyosawa
Background . A new agent, potassium-competitive acid blocker vonoprazan (VPZ) has potent acid-inhibitory effects and may offer advantages over conventional H. pylori eradication therapies. We aimed to compare the eradication rate between VPZ-based treatment and PPI-based one. Methods . This randomized controlled trial was designed to assign 141 patients with H. pylori- positive gastritis to VPZ group (VPZ 20 mg, amoxicillin 750 mg, and clarithromycin 200 or 400 mg twice daily for 7 days) or PPI group (rabeprazole 20 mg or lansoprazole 30 mg, amoxicillin 750 mg, and clarithromycin 200 or 400 mg twice daily for 7 days)...
2017: Canadian Journal of Gastroenterology & Hepatology
Daisuke Matsui, Isao Watanabe, Teruhide Koyama, Etsuko Ozaki, Nagato Kuriyama, Shigeto Mizuno, Yoshiyuki Watanabe
Osteopenia is a condition in which bone mineral density (BMD) is lower than normal. Exercise increases BMD in both the young and adults. This study aimed to compare the radial apparent BMD (aBMD) in Japanese females who are Kendo practitioners (KPs) and those with no regular exercise habits (no-REH). The analysis participants consisted of 45 KPs (mean age: 49.4 years old) and 110 no-REH (mean age: 48.8 years old). Radial aBMD was measured using an ultrasonic bone densitometry system. Radial aBMD in KPs was 196...
September 2017: Journal of Sports Sciences
Shinya Kisi, Munehito Yoshida
[Purpose] We investigated Achilles tendon injury in Kendo players in junior and senior high schools to obtain a possible indicator for preventing an outbreak of Achilles tendon injury and tendonitis, possible risk factors concerning foot function and morphology were extracted. [Subjects and Methods] The subjects were 60 Kendo players aged 14-18 years from Wakayama Prefecture, Japan (33 boys and 27 girls). A questionnaire survey was conducted on the past history, current status, time of occurrence about Achilles tendon pain or rupture, and site of Achilles tendon pain or rupture...
February 2017: Journal of Physical Therapy Science
Feng-Hua Tsai, I-Hua Chu, Chun-Hao Huang, Jing-Min Liang, Jia-Hroung Wu, Wen-Lan Wu
CONTEXT: It has been reported that there is a high rate of Achilles tendon injury among kendo athletes. For protection and to support the area, kendo athletes habitually use taping during practice or games. OBJECTIVE: To investigate the effect of various taping techniques on injury prevention and functional performance in kendo athletes. DESIGN: Case-control study. SETTING: Laboratory. PARTICIPANTS: 15 University Kendo Team athletes with at least 2 y kendo experience...
March 1, 2018: Journal of Sport Rehabilitation
Shinpei Matsuda, Hitoshi Yoshimura, Tadanori Hamano, Kazuo Sano
Sensory and motor neuropathy of the trigeminal nerve due to trauma is quite rare. Furthermore, there have been no detailed reports on occlusal abnormalities and trismus associated with post-traumatic trigeminal motor neuropathy. Here, the authors report a case of trigeminal motor neuropathy and trigeminal sensory neuropathy in all 3 divisions caused by an orbital stab wound. During kendo practice, a 61-year-old man was injured in his right medial canthus with the splinter of a broken bamboo sword. Imaging examinations did not show a brain injury or orbital bone fracture...
January 2017: Journal of Craniofacial Surgery
Takashi Higaki, Toshiyuki Chisaka, Tomozo Moritani, Masaaki Ohta, Hidemi Takata, Toshifumi Yamauchi, Youhei Yamaguchi, Kyoko Konishi, Eiichi Yamamoto, Fumihiro Ochi, Mariko Eguchi, Minenori Eguchi-Ishimae, Yoshihide Mitani, Eiichi Ishii
BACKGROUND: Recently, a student died of idiopathic ventricular fibrillation in a school where an automated external defibrillator (AED) had been installed. The tragedy could not be prevented because the only AED in the school was installed in the teachers' office, far from the school ground where the accident took place. This prompted establishment of a multiple AED system in schools. The aim of this study was to analyze the efficacy of the multiple AED system to prevent sudden death in school-aged children...
December 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
Hansang Jung, Namju Lee, Sok Park
PURPOSE: The purpose of this study was to determine the interaction of ACTN3 gene polymorphism and muscle imbalance effects on kinematic efficiency changes in combat sports athletes. METHODS: Six types of combat sports athletes (Judo, Taekwondo, boxing, kendo, wrestling, and Korean Ssi-reum) participated in the study. ATCN3 gene polymorphism and muscle imbalance in lower extremity were evaluated followed by analysis of differences of moment in hip, knee, and ankle joint during V-cut jumping and stop...
June 2016: Journal of Exercise Nutrition & Biochemistry
Takeshi Otsuki, Kazuhiro Shimizu, Asako Zempo-Miyaki, Seiji Maeda
Decreases in saliva secretion compromise food mastication and swallowing, reduce mucosal immune function, and increase the risk for oral diseases like dental caries. Chlorella is a green alga that contains a variety of nutrients including amino acids, vitamins, and minerals. In our previous study, Chlorella-derived multicomponent supplementation did not affect salivary flow rates in healthy young individuals, but Chlorella-derived supplementation attenuated a decrease in saliva secretion that was observed during a kendo training camp...
July 2016: Journal of Clinical Biochemistry and Nutrition
Akira Kurosu, Kazumi Kuroyanagi, Shinobu Yamauchi, Kazunobu Omura, Kazuyuki Saito
Anomalous origin of the coronary artery (AOCA) is a rare, but important cause of sudden cardiac death among young athletes. Nine autopsy cases (8 male, 1 female; mean age, 17.9 years; age range, 11-31 years) of sudden death during or just after exercise caused by AOCA were reviewed. The exercises performed at the time of death were running (4 cases), soccer (2 cases), and baseball, swimming and kendo (Japanese swordsmanship) (1 case each). In 6 cases, the left coronary artery arose from the right sinus of Valsalva, and in 3, the right coronary artery from the left sinus...
March 2016: Journal of Forensic Sciences
Satoru Atsumi, Yuji Arai, Ko Kato, Akinobu Nishimura, Shigeto Nakazora, Shuji Nakagawa, Kazuya Ikoma, Hiroyoshi Fujiwara, Akihiro Sudo, Toshikazu Kubo
Among stress fractures associated with sports activities, patellar stress fracture is rare. Regarding patella stress fractures, so far only distal transverse or lateral longitudinal fractures have been reported, but there are no reports of transverse fractures occurring in the proximal patella. We describe an extremely rare case of transverse stress fracture of proximal patella in a 9-year-old athlete.A 9-year old boy, who participated in sports (sprints and Kendo) presented with left knee pain without any external injury...
February 2016: Medicine (Baltimore)
Jin Hyung Lee, Hyoung Seop Kim, Seung Ho Joo
Annular pulley injury of fingers is usually observed in rock climbers who support their entire body weight with flexed fingers during climbing. But these lesions can also follow trivial trauma, such as lifting heavy objects with the fingertips, or during sports and recreational activities. The A2 and A4 pulleys are most usually involved and reported most frequently. However, traumatic A1 pulley rupture has not been reported yet, to the best of our knowledge. Kendo is a very vigorous martial art with frequent physical contact...
October 2015: Annals of Rehabilitation Medicine
Mark Schultzel, Matthew Schultzel, Brock Wentz, Mark Bernhardt
OBJECTIVE: Kendo is a Japanese martial art analogous to fencing, which is becoming increasingly popular worldwide. The large number of participants creates a need to assess injury patterns to better train them. The purpose of this study is to describe current injury rates in kendo and compare these rates to other martial arts. METHODS: This retrospective study used an online questionnaire sent to 500 active members of the All United States Kendo Federation and World Kendo Federation...
2016: Physician and Sportsmedicine
Ji-Woong Noh, Byoung-Sun Park, Mee-Young Kim, Lim-Kyu Lee, Seung-Min Yang, Won-Deok Lee, Yong-Sub Shin, Ju-Hyun Kim, Jeong-Uk Lee, Taek-Yong Kwak, Tae-Hyun Lee, Ju-Young Kim, Jaehong Park, Junghwan Kim
[Purpose] This study describes the characteristics of injuries in strike and non-strike combat sports, and the results are intended for use in the area of sports physiotherapy research. [Subjects and Methods] The study was conducted on 159 athletes involved in a variety of combat sports. The participants included elite college players of the following sports: judo (47), ssireum (19), wrestling (13), kendo (30), boxing (16), and taekwondo (34). Of the participants, 133 were male and 26 were female. In the case of ssireum and boxing, all of the athletes were male...
August 2015: Journal of Physical Therapy Science
Kazuhiro Shimizu, Michihiro Kon, Yuko Tanimura, Yukichi Hanaoka, Fuminori Kimura, Takao Akama, Ichiro Kono
This study examined changes in toll-like receptor 4 (TLR-4)-expressing monocytes and lymphocyte subpopulations in response to continuous intensive exercise training in athletes, as well as the effect of coenzyme Q10 (CoQ10) supplementation on these changes. Eighteen male elite kendo athletes in Japan were randomly assigned to a CoQ10-supplementation group (n = 9) or a placebo-supplementation group (n = 9) using a double-blind method. Subjects in the CoQ10 group took 300 mg CoQ10 per day for 20 days. Subjects in the placebo group took the same dosage of placebo...
June 2015: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
H Arikawa, T Terada, T Takahashi, K Kizaki, H Imai, S Era
One distinctive trait of kendo, the Japanese martial art of fencing, is the execution of sustained, high-effort vocalizations during actions. The purpose of this study was to determine the effect of these vocalizations on respiratory functions. First, the intensity of 3 kendo exercises was quantified by measuring oxygen uptake (V̇O2) and comparing it with V̇O2max measured during treadmill tests of 8 university kendo athletes. Respiratory variables of these 8 athletes were then analyzed using a portable breath gas analyzer during the most intensive kendo exercise, kakari-keiko, with and without vocalization...
June 2015: International Journal of Sports Medicine
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