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https://www.readbyqxmd.com/read/28736860/annual-research-review-dna-methylation-as-a-mediator-in-the-association-between-risk-exposure-and-child-and-adolescent-psychopathology
#1
REVIEW
Edward D Barker, Esther Walton, Charlotte A M Cecil
BACKGROUND: DNA methylation (DNAm) is a potential mechanism for propagating the effects of environmental exposures on child and adolescent mental health. In recent years, this field has experienced steady growth. METHODS: We provide a strategic review of the current child and adolescent literature to evaluate evidence for a mediating role of DNAm in the link between environmental risks and psychopathological outcomes, with a focus on internalising and externalising difficulties...
July 24, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28729357/association-between-maternal-childhood-trauma-and-offspring-childhood-psychopathology-mediation-analysis-from-the-alspac-cohort
#2
Dominic T Plant, Fergal W Jones, Carmine M Pariante, Susan Pawlby
BackgroundStudies have shown that a mother's history of child maltreatment is associated with her child's experience of internalising and externalising difficulties.AimsTo characterise the mediating pathways that underpin this association.MethodData on a mother's history of child maltreatment, depression during pregnancy, postnatal depression, maladaptive parenting practices and her child's experience of maltreatment and internalising and externalising difficulties were analysed in an Avon Longitudinal Study of Parents and Children (ALSPAC) sample of 9397 mother-child dyads followed prospectively from pregnancy to age 13...
July 20, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28721740/clinical-features-and-subjective-physiological-responses-to-emotional-stimuli-in-the-presence-of-emotion-dysregulation-in-attention-deficit-hyperactivity-disorder
#3
Candan Taskiran, Serkan Karaismailoglu, Halime Tuna Cak Esen, Zeynep Tuzun, Aysen Erdem, Zeynep Dicle Balkanci, Anil Barak Dolgun, Sadriye Ebru Cengel Kultur
INTRODUCTION: Emotion dysregulation (ED) has long been recognized in clinical descriptions of attention-deficit hyperactivity disorder (ADHD), but a renewed interest in ED has advanced research on the overlap between the two entities. Autonomic reactivity (AR) is a neurobiological correlate of emotion regulation; however, the association between ADHD and AR remains unclear. Our aim was to explore the clinical differences, AR, and subjective emotional responses to visual emotional stimuli in ADHD children with and without ED...
July 19, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28714126/annual-research-review-early-adversity-the-hypothalamic-pituitary-adrenocortical-axis-and-child-psychopathology
#4
REVIEW
Kalsea J Koss, Megan R Gunnar
BACKGROUND: Research on early adversity, stress biology, and child development has grown exponentially in recent years. FINDINGS: We review the current evidence for the hypothalamic-pituitary-adrenocortical (HPA) axis as a stress-mediating mechanism between various forms of childhood adversity and psychopathology. We begin with a review of the neurobiology of the axis and evidence for relations between early adversity-HPA axis activity and HPA axis activity-psychopathology, as well as discuss the role of regulatory mechanisms and sensitive periods in development...
July 17, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28708033/neuropsychological-profile-and-social-cognition-in-congenital-central-hypoventilation-syndrome-cchs-correlation-with-neuroimaging-in-a-clinical-case
#5
Borja Esteso Orduña, Raquel Seijas Gómez, Elena García Esparza, Emily M Briceño, Javier Melero Llorente, María de la Concepción Fournier Del Castillo
INTRODUCTION: Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder due to paired-like homeobox gene (PHOX2B) mutations. CCHS patients suffer from dysregulation of the autonomic nervous system characterized by the absence of or extremely reduced response to hypercapnia and hypoxia, with neuropsychological deficits. The aim of this exploratory study is to describe the longitudinal neuropsychological profile and its correlations with magnetic resonance imaging (MRI) of a child with CCHS with a PHOX2B mutation...
July 14, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28705086/longitudinal-relations-between-childhood-maltreatment-maltreatment-specific-shame-and-postpartum-psychopathology
#6
Rena A Menke, Diana Morelen, Valerie A Simon, Katherine L Rosenblum, Maria Muzik
The persistence of shame-based reactions to child maltreatment (CM) has been associated with poor posttraumatic adjustment. Despite evidence that the postpartum period is a vulnerable time for women with CM histories, little is known about the consequences of maltreatment-specific (MS) shame for postpartum functioning. The current study examined individual differences in MS shame among a sample of women during the postpartum period ( n = 100) as well as prospective relations from MS shame to postpartum psychopathology at 6-, 12-, 15-, and 18-month postpartum...
January 1, 2017: Child Maltreatment
https://www.readbyqxmd.com/read/28700013/correlations-between-caregiver-psychiatric-symptoms-and-offspring-psychopathology-in-a-low-resource-setting
#7
Camila T Matsuzaka, Milton L Wainberg, Andrea Norcini Pala, Elis V Hoffmann, Bruno M Coimbra, Rosaly F Braga, Cristiane S Duarte, Annika C Sweetland, Marcelo F Mello
Objective: Associations between parental/caregiver depression and adverse child outcomes are well established and have been described through one or more mechanisms: child psychopathology following exposure to a depressed caregiver, child psychopathology exacerbating a caregiver's depression, and caregiver and offspring depression sharing the same etiology. Data from low and middle-income countries is scarce. We examined correlations between common symptoms of mental disorders in caregivers and their offspring's psychopathology in a Brazilian sample...
July 6, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28693700/longitudinal-effects-of-an-intervention-on-perfectionism-in-adolescents
#8
Carmen Bento, Ana T Pereira, Carolina Roque, Jorge M Tavares Saraiva, António J Ferreira Macedo E Santos
Perfectionism is a personality disposition characterized by a person´s striving for flawlessness and the setting of excessively high performance standards. This trait has been associated with a broad range of psychopathological conditions. Consequently, prevention of its harmful effects must start early. OBJECTIVE: To investigate if one group session to manage perfectionism has the effect of reducing the levels of this trait, two and six months later. METHOD: A community-based sample of 978 Portuguese adolescents from three different high schools completed a self-reporting questionnaire including the Child and Adolescent Perfectionism Scale, before and after one skill session...
August 2017: Psicothema
https://www.readbyqxmd.com/read/28687638/behavioral-risk-assessment-from-newborn-to-preschool-the-value-of-older-siblings
#9
Michelle Rodrigues, Noam Binnoon-Erez, Andre Plamondon, Jennifer M Jenkins
OBJECTIVES: The aim of this study was to examine the plausibility of a risk prediction tool in infancy for school-entry emotional and behavioral problems. Familial aggregation has been operationalized previously as maternal psychopathology. The hypothesis was tested that older sibling (OS) psychopathology, as an indicator of familial aggregation, would enable a fair level of risk prediction compared with previous research, when combined with traditional risk factors. METHODS: By using a longitudinal design, data on child and family risk factors were collected on 323 infants (M = 2...
July 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/28681149/young-children-s-physiological-reactivity-during-memory-recall-associations-with-posttraumatic-stress-and-parent-physiological-synchrony
#10
Sarah A O Gray, Rebecca S Lipschutz, Mike S Scheeringa
Autonomic reactivity is implicated in stress response and social engagement - both key components of posttraumatic stress disorder (PTSD) - but few studies have examined autonomic reactivity in pediatric samples, and no known studies have examined physiological synchrony among children with PTSD and caregivers. In a sample of 247 young children (94 girls, 153 boys), most (85%) of whom had exposure to trauma and 40% who met criteria for PTSD, we examined children's patterns of respiratory sinus arrhythmia (RSA) at baseline and in response to a memory recall task, as well as correspondence between parents' and children's RSA...
July 6, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28678525/the-natural-course-of-anxiety-symptoms-in-early-adolescence-factors-related-to-persistence
#11
Núria Voltas, Carmen Hernández-Martínez, Victoria Arija, Josefa Canals
BACKGROUND AND OBJECTIVES: Anxiety disorders are the most common mental health problems during childhood and adolescence. This study examined the course of anxiety symptoms in early adolescents from the general population over three phases. DESIGN: Prospective cohort study. METHODS: Two hundred and forty-two participants (mean-age of 13.52) from a baseline sample of 1514 (mean-age of 10.23) were followed up three times. Of the 1514 children, those with emotional risk and controls without risk constituted the second-phase sample (n = 562; mean-age of 11...
July 5, 2017: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/28675949/comt-and-dat1-polymorphisms-moderate-the-indirect-effect-of-parenting-behavior-on-youth-adhd-symptoms-through-neurocognitive-functioning
#12
Julia E Morgan, Barbara Caplan, Irene Tung, Amanda N Noroña, Bruce L Baker, Steve S Lee
Although gene × environment interactions contribute to youth attention-deficit/hyperactivity disorder (ADHD) symptoms, the pathways mediating these influences are unknown. We tested genetic moderation of indirect effects from parenting behavior to youth ADHD symptoms through multiple neurocognitive factors. Two hundred and twenty-nine youth with and without ADHD were assessed at baseline (Wave 1; ages 5-10) and at a 2-year follow-up (Wave 2; ages 7-13). At Wave 1, youth completed a neurocognitive battery including measures of response inhibition, visuospatial working memory, and fluid reasoning, and a standardized parent-child interaction task yielding observational measures of positive and negative parenting...
July 4, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28671298/explaining-the-relationship-between-temperament-and-symptoms-of-psychiatric-disorders-from-preschool-to-middle-childhood-hybrid-fixed-and-random-effects-models-of-norwegian-and-spanish-children
#13
Lars Wichstrøm, Eva Penelo, Kristine Rensvik Viddal, Nuria de la Osa, Lourdes Ezpeleta
BACKGROUND: Four explanations for the concurrent and prospective associations between temperament and psychopathology in children have been suggested: predisposition, complication/scar, common cause/continuity, and pathoplasty/exacerbation. Because the confounding effects of common causes have not been ruled out in prior work, the support for the various explanations is uncertain. METHODS: Screen-stratified community samples of 4-year olds in Trondheim, Norway (n = 1,042), and 3-year olds in Barcelona, Spain (n = 622), were assessed biennially for symptoms of attention-deficit/hyperactivity (ADHD), oppositional defiant (ODD), conduct (CD), anxiety, and depressive disorders through interviewer-based psychiatric interviews across four waves of data collection...
July 3, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28667426/maternal-depressive-symptoms-during-pregnancy-are-associated-with-amygdala-hyperresponsivity-in-children
#14
Noortje J F van der Knaap, Floris Klumpers, Hanan El Marroun, Sabine Mous, Dirk Schubert, Vincent Jaddoe, Albert Hofman, Judith R Homberg, Henning Tiemeier, Tonya White, Guillén Fernández
Depression during pregnancy is highly prevalent and has a multitude of potential risks of the offspring. Among confirmed consequences is a higher risk of psychopathology. However, it is unknown how maternal depression may impact the child's brain to mediate this vulnerability. Here we studied amygdala functioning, using task-based functional MRI, in children aged 6-9 years as a function of prenatal maternal depressive symptoms selected from a prospective population-based sample (The Generation R Study). We show that children exposed to clinically relevant maternal depressive symptoms during pregnancy (N = 19) have increased amygdala responses to negative emotional faces compared to control children (N = 20) [F(1,36) 7...
June 30, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28666366/child-maltreatment-and-clinical-outcome-in-individuals-at-ultra-high-risk-for-psychosis-in-the-eu-gei-high-risk-study
#15
Tamar C Kraan, Eva Velthorst, Manouk Themmen, Lucia Valmaggia, Matthew J Kempton, Phillip McGuire, Jim van Os, Bart P F Rutten, Filip Smit, Lieuwe de Haan, Mark van der Gaag
Background: Child maltreatment has been associated with a wide range of mental disorders in adulthood. Whether child maltreatment is specifically associated with psychosis risk in individuals at ultra-high risk (UHR) for psychosis, or leads to a general vulnerability for overall psychopathology in the UHR stage remains unclear. The present study examines the association between child maltreatment and transition to psychosis and other mental disorders. Methods: The sample consisted of 259 UHR individuals from the EUropean network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) study...
June 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28660407/examining-the-relationship-between-parent-and-child-psychopathology-in-treatment-seeking-veterans
#16
Alyson K Zalta, Eric Bui, Niranjan S Karnik, Philip Held, Lauren M Laifer, Julia C Sager, Denise Zou, Paula K Rauch, Naomi M Simon, Mark H Pollack, Bonnie Ohye
This study aimed to examine: (1) the relationship between parental psychopathology and child psychopathology in military families and (2) parenting sense of competence as a mediator of the relationship between veteran psychopathology and child psychopathology. As part of their standard clinical evaluations, 215 treatment-seeking veterans who reported having a child between the ages of 4 and 17 were assessed for psychopathology (posttraumatic stress disorder, depression, anxiety, and stress), their sense of competence as a parent, and their child's psychopathology (internalizing, externalizing, and attentional symptoms)...
June 28, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28646354/associations-between-race-and-eating-disorder-symptom-trajectories-in-black-and-white-girls
#17
Lindsay P Bodell, Jennifer E Wildes, Yu Cheng, Andrea B Goldschmidt, Kate Keenan, Alison E Hipwell, Stephanie D Stepp
Epidemiological research suggests racial differences in the presentation of eating disorder symptoms. However, no studies have examined associations between race and eating disorder symptom trajectories across youth and adolescence, which is necessary to inform culturally sensitive prevention programs. The purpose of the current study was to examine the trajectories of eating disorder symptoms from childhood to young adulthood and to examine whether race was associated with trajectory group membership. Data were drawn from 2,305 Black and White girls who participated in a community-based longitudinal cohort study (Pittsburgh Girls Study) examining the development of psychopathology...
June 23, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28645979/the-2015-middle-childhood-survey-mcs-of-mental-health-and-well-being-at-age-11-years-in-an-australian-population-cohort
#18
Kristin R Laurens, Stacy Tzoumakis, Kimberlie Dean, Sally A Brinkman, Miles Bore, Rhoshel K Lenroot, Maxwell Smith, Allyson Holbrook, Kim M Robinson, Robert Stevens, Felicity Harris, Vaughan J Carr, Melissa J Green
PURPOSE: The Middle Childhood Survey (MCS) was designed as a computerised self-report assessment of children's mental health and well-being at approximately 11 years of age, conducted with a population cohort of 87 026 children being studied longitudinally within the New South Wales (NSW) Child Development Study. PARTICIPANTS: School Principals provided written consent for teachers to administer the MCS in class to year 6 students at 829 NSW schools (35.0% of eligible schools)...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28644929/short-interpregnancy-intervals-maternal-folate-levels-and-infants-born-small-for-gestational-age-a-preliminary-study-in-a-canadian-supplement-using-population
#19
Buffy Chen, Prescilla Carrion, Ravneet Grewal, Angela Inglis, Catriona Hippman, Emily Morris, Heather J Andrighetti, Arianne Albert, Jehannine Austin
BACKGROUND: Short interpregnancy intervals (SIPI) have been associated with increased risks for adverse neonatal outcomes including preterm delivery and infants small for gestational age (SGA). It has been suggested that mechanistically, adverse neonatal outcomes after SIPI arise due to insufficient recovery of depleted maternal folate levels prior to the second pregnancy. However, empirical data are lacking regarding physiological folate levels in pregnant women with SIPI, and relationships between quantified physiological folate levels and outcomes like SGA...
June 23, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28644832/parent-child-discrepancies-in-the-report-of-adolescent-emotional-and-behavioral-problems-in-taiwan
#20
Ying-Yeh Chen, Suk-Yin Ho, Pei-Chen Lee, Chia-Kai Wu, Susan Shur-Fen Gau
The majority of studies on parent-child discrepancies in the assessment of adolescent emotional and behavioral problems have been conducted in Western countries. It is believed that parent-adolescent agreement would be higher in societies with a strong culture of familism. We examined whether parent-adolescent discrepancies in the rating of adolescent emotional and behavioral problems are related to parental and family factors in Taiwan. Participants included 1,421 child-parent pairs of 7th-grade students from 12 middle schools in Northern Taiwan and their parents...
2017: PloS One
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