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Fibrin glue

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https://www.readbyqxmd.com/read/28799873/-birdlime-technique-using-tachosil-tissue-sealing-sheet-soaked-with-fibrin-glue-for-sutureless-vessel-transposition-in-microvascular-decompression-operative-technique-and-nuances
#1
Naoki Otani, Terushige Toyooka, Kazuya Fujii, Kosuke Kumagai, Satoru Takeuchi, Arata Tomiyama, Yasuaki Nakao, Takuji Yamamoto, Kojiro Wada, Kentaro Mori
OBJECTIVE Microvascular decompression (MVD) is effective for the treatment of trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia. The transposition technique is the standard procedure to avoid adhesions and granuloma around the decompression site but is more complex and difficult to perform than the interposition technique. The authors describe a simple and safe MVD transposition procedure they call the "birdlime" technique, which uses a tissue glue-coated collagen sponge soaked with fibrin glue, and the results of this technique...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28795641/fixation-of-hydrogel-constructs-for-cartilage-repair-in-the-equine-model-a-challenging-issue
#2
Irina A D Mancini, Rafael Angel Vindas Bolanos, Harold Brommer, Miguel Castilho, Alexandro Ribeiro, J P A M van Loon, Anneloes Mensinga, Mattie H P Van Rijen, Jos Malda, René van Weeren
<u><b>Objective</b></u> To evaluate the use of commercial and autologous fibrin glue and of an alternative method based on a 3D-printed polycaprolactone (PCL) anchor for the fixation of hydrogel-based scaffolds in an equine model for cartilage repair. <u><b>Methods</b></u> In a first study, three different hydrogel-based materials were orthotopically implanted in nine horses for 1-4 weeks in 6mm diameter full thickness cartilage defects in the medial femoral trochlear ridge and fixated with commercially available fibrin glue (CFG)...
August 10, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28771731/repairing-the-vibratory-vocal-fold
#3
Jennifer L Long
OBJECTIVE: A vibratory vocal fold replacement would introduce a new treatment paradigm for structural vocal fold diseases such as scarring and lamina propria loss. This work implants a tissue-engineered replacement for vocal fold lamina propria and epithelium in rabbits and compares histology and function to injured controls and orthotopic transplants. Hypotheses were that the cell-based implant would engraft and control the wound response, reducing fibrosis and restoring vibration. STUDY DESIGN: Translational research...
August 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28763366/does-bloodcare-powder-prevent-postoperative-chylous-ascites-after-lymphadenectomy-for-gynecological-malignancies
#4
Kemal Güngördük, Özgü Celikkol Güngördük, I Aykut Ozdemir, Mehmet Gokcu, Muzaffer Sanci
OBJECTIVE: The aim of this study was to evaluate the effect of an intraoperative hemostatic cellulose agent (BLOODCARE powder [Life Line, Brno, Czech Republic]) on reducing the incidence of postoperative chylous ascites (PCA) after complete pelvic and para-aortic lymphadenectomy (PPALN) in patients with gynecological cancers treated with laparotomy. METHODS: This case control study reviewed 150 patients with gynecological cancer who underwent PPALN. In the study group (n = 75), BLOODCARE powder was applied below the left renal vein and bilateral obturator fossa...
August 1, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28761338/a-review-of-fibrin-and-fibrin-composites-for-bone-tissue-engineering
#5
REVIEW
Alireza Noori, Seyed Jamal Ashrafi, Roza Vaez-Ghaemi, Ashraf Hatamian-Zaremi, Thomas J Webster
Tissue engineering has emerged as a new treatment approach for bone repair and regeneration seeking to address limitations associated with current therapies, such as autologous bone grafting. While many bone tissue engineering approaches have traditionally focused on synthetic materials (such as polymers or hydrogels), there has been a lot of excitement surrounding the use of natural materials due to their biologically inspired properties. Fibrin is a natural scaffold formed following tissue injury that initiates hemostasis and provides the initial matrix useful for cell adhesion, migration, proliferation, and differentiation...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28757691/cut-and-place-technique-of-pterygium-excision-with-autograft-without-using-sutures-or-glue-our-experience
#6
Jagdish Bhatia, Mathew Varghese, Bindu Narayanadas, Arti Bhatia
BACKGROUND: Conjunctival sutures used in pterygium surgery are not only time-consuming process but also may lead to local complications such as discomfort, scarring, granuloma, or infection. Plasma-derived products such as fibrin glue may produce possible hypersensitivity reactions whereas the risk of viral transmission remains theoretically possible. We describe a simple method of achieving conjunctival autograft adherence during pterygium surgery avoiding potential complications associated with the use of fibrin glue or sutures...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28754649/stretching-single-fibrin-fibers-hampers-their-lysis
#7
Wei Li, Tomas Lucioni, Rongzhong Li, Keith Bonin, Samuel S Cho, Martin Guthold
Blood clots, whose main structural component is a mesh of microscopic fibrin fibers, experience mechanical strain from blood flow, clot retraction and interactions with platelets and other cells. We developed a transparent, striated and highly stretchable substrate made from fugitive glue (a styrenic block copolymer) to investigate how mechanical strain affects lysis of single, suspended fibrin fibers. In this suspended fiber assay, lysis manifested itself by fiber elongation, thickening (disassembly), fraying and collapse...
July 25, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28753648/lipoxin-a4-encapsulated-in-plga-microparticles-accelerates-wound-healing-of-skin-ulcers
#8
Mouzarllem Barros Reis, Priscilla Aparecida Tartari Pereira, Guilherme Ferreira Caetano, Marcel Nani Leite, Alyne Fávero Galvão, Francisco Wanderley Garcia Paula-Silva, Marco Andrey Cipriani Frade, Lúcia Helena Faccioli
Lipoxin A4 (LXA4) is involved in the resolution of inflammation and wound healing; however, it is extremely unstable. Thus, to preserve its biological activities and confer stability, we encapsulated LXA4 in poly-lactic-co-glycolic acid (PLGA) microparticles (LXA4-MS) and assessed its application in treating dorsal rat skin lesions. Ulcers were sealed with fibrin adhesive and treated with either LXA4-MS, unloaded microparticles (Un-MS), soluble LXA4, or PBS/glue (vehicle). All groups were compared at 0, 2, 7, and 14 days post-lesions...
2017: PloS One
https://www.readbyqxmd.com/read/28735765/incidental-durotomy-during-total-en-bloc-spondylectomy
#9
Noriaki Yokogawa, Hideki Murakami, Satoru Demura, Satoshi Kato, Katsuhito Yoshioka, Hiroyuki Tsuchiya
BACKGROUND CONTEXT: The incidence of incidental durotomy (ID) during total en bloc spondylectomy (TES) tends to be higher than that during other spinal surgeries because of the peculiarities of TES, including its highly invasive nature, epidural tumor extension, and use in patients who often have complicated medical backgrounds. However, there have been no detailed reports on ID associated with TES. PURPOSE: The study aimed to investigate ID during TES in detail...
July 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28718327/fibrin-glue-increases-the-tensile-strength-of-conduit-assisted-primary-digital-nerve-repair
#10
Jessica R Childe, Steven Regal, Patrick Schimoler, Alexander Kharlamov, Mark C Miller, Peter Tang
BACKGROUND: An ideal peripheral nerve repair construct does not currently exist. Our primary goal was to determine whether fibrin glue adds to the tensile strength of conduit-assisted primary digital nerve repairs. Our secondary goal was to evaluate the impact of varying suture number and location on the tensile strength. METHODS: Ninety cadaveric digital nerves were harvested and divided equally into the following repair groups: A (4/4), B (2/2), C (0/2), D (0/1), and E (0/0) with the first number referring to the number of sutures at the coaptation and the second number referring to the number of sutures at each proximal and distal end of the nerve-conduit junction...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28713066/approaches-for-stricture-prevention-after-esophageal-endoscopic-resection
#11
REVIEW
Seiichiro Abe, Prasad G Iyer, Ichiro Oda, Nobuo Kanai, Yutaka Saito
BACKGROUND AND AIMS: Endoscopic resection of extensive esophageal lesions has become more common as endoscopic resection techniques and equipment has developed. However, extensive esophageal endoscopic resections can cause postoperative esophageal strictures, which have a negative impact on the quality of life of patients. We aimed to review current treatments and innovative approaches to prevent esophageal strictures after widespread endoscopic resection of esophageal lesions. METHODS: We performed a comprehensive literature search using predetermined search terms from 2000 to 2016 to identify relevant articles and summarized their results as a narrative review...
July 13, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28704320/recurrence-rate-and-graft-stability-with-fibrin-glue-compared-with-suture-and-autologous-blood-coagulum-for-conjunctival-autograft-adherence-in-pterygium-surgery-a-meta-analysis
#12
Rituparna Maiti, Somnath Mukherjee, Debasish Hota
PURPOSE: To minimize recurrence and improve graft stability after pterygium surgery, conjunctival autograft adherence is done using fibrin glue (FG) or autologous blood coagulum (ABC). But there are studies that have reported conflicting or inconclusive results. This meta-analysis was conducted to evaluate the postoperative recurrence rate and graft stability after using FG, sutures, and ABC. METHODS: MEDLINE, Cochrane databases, and ICTRP were searched and PRISMA guidelines as well as recommended meta-analysis practices were followed...
July 11, 2017: Cornea
https://www.readbyqxmd.com/read/28697892/bronchopleural-fistula-after-pneumonectomy-risk-factors-and-management-focusing-on-open-window-thoracostomy
#13
Antonio Mazzella, Alessandro Pardolesi, Patrick Maisonneuve, Francesco Petrella, Domenico Galetta, Roberto Gasparri, Lorenzo Spaggiari
OBJECTIVE: To evaluate principal risk factors and different therapeutic approaches for postpneumonectomy bronchopleural fistula (BPF), focusing on open window thoracostomy (OWT). METHODS: We retrospectively reviewed all patients treated by pneumonectomy for lung cancer between 1999 and 2014. We evaluated preoperative, operative, and postoperative data; interval between operation and fistula formation; and size, treatment, and predicting factors of BPF. Cumulative incidence curves for the development of BPF were drawn according to the Kaplan-Meier method...
June 12, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28689686/clinical-evaluations-of-complete-autologous-fibrin-glue-produced-by-the-cryoseal-%C3%A2-fs-system-and-polyglycolic-acid-sheets-as-wound-coverings-after-oral-surgery
#14
Atsumu Kouketsu, Shinnosuke Nogami, Minami Yamada-Fujiwara, Hirokazu Nagai, Kensuke Yamauchi, Shiro Mori, Hitoshi Miyashita, Tadashi Kawai, Aritsune Matsui, Yoshihiro Kataoka, Norihisa Satomi, Yushi Ezoe, Satoko Abe, Yuri Takeda, Takeshi Tone, Bunnichi Hirayama, Tsuyoshi Kurobane, Kazuki Tashiro, Yuta Yanagisawa, Tetsu Takahashi
The CryoSeal(®) FS System has been recently introduced as an automated device for the production of complete fibrin glue from autologous plasma, rather than from pool allogenic or cattle blood, to prevent viral infection and allergic reaction. We evaluated the effectiveness of complete autologous fibrin glue and polyglycolic acid (PGA) sheet wound coverings in mucosa defect oral surgery. Postoperative pain, scar contracture, ingestion, tongue dyskinesia, and postoperative bleeding were evaluated in 12 patients who underwent oral (including the tongue) mucosa excision, and received a PGA sheet and an autologous fibrin glue covering...
June 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28688332/regenerative-capacity-of-allogenic-gingival-margin-derived-stem-cells-with-fibrin-glue-on-albino-rats-partially-dissected-submandibular-salivary-glands
#15
Noura Abd El-Latif, Mohamed Abdulrahman, Mohamad Helal, Mohammed E Grawish
OBJECTIVE: To evaluate the possible regenerative effect of allogenic gingival margin-derived stem cells (GMSCs) with or without autologous fibrin glue on partially dissected submandibular salivary glands of albino rats. METHODS: Forty rats were randomly divided into four equal groups. Group I, where no operation was performed, was considered the negative control. Group II rats were considered the positive control and were subjected to a rectangular cut on the outer surface of the center right of the submandibular salivary gland and received no other treatment...
June 27, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28686663/in-vitro-release-pharmacokinetics-of-amikacin-teicoplanin-and-polyhexanide-in-a-platelet-rich-fibrin-layer-prf-a-laboratory-evaluation-of-a-modern-autologous-wound-treatment
#16
Daniela Knafl, Florian Thalhammer, Matthias G Vossen
OBJECTIVES: Platelet rich fibrin (PRF) is an autologous fibrin glue, produced from patients' blood, which, besides intraoperative use, has applications in the treatment of infected wounds. The combination with antimicrobial agents results in a prolonged antibacterial effect allowing for wound dressing change intervals of seven days even in infected wounds. The aim of this study was to evaluate release kinetics of amikacin, teicoplanin or polyhexanide from a PRF-layer. METHODS: PRF mixed with teicoplanin, amikacin or polyhexanide was sprayed on a silicon gauze patch and put on a colombia agar with bacteria with known minimal inhibitory concentration (MIC) and incubated for 24 hours and afterwards transferred to another agar with the same bacterial strain...
2017: PloS One
https://www.readbyqxmd.com/read/28680888/early-graft-tunnel-healing-after-anterior-cruciate-ligament-reconstruction-with-intratunnel-injection-of-bone-marrow-mesenchymal-stem-cells-and-vascular-endothelial-growth-factor
#17
Rosy Setiawati, Dwikora Novembri Utomo, Fedik Abdul Rantam, Nadia Nastassia Ifran, Nicolaas C Budhiparama
BACKGROUND: Bone marrow mesenchymal stem cells (BM-MSCs) are multipotent adult stem cells and have become an important source of cells for engineering tissue repair and cell therapy. Vascular endothelial growth factor (VEGF) promotes angiogenesis and contributes fibrous integration between tendon and bone during the early postoperative stage. Both MSCs and VEGF can stimulate cell proliferation, differentiation, and matrix deposition by enhancing angiogenesis and osteogenesis of the graft in the tunnel...
June 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28674858/self-made-cryopreservative-fibrin-glue-applied-in-pterygium-surgery-a-novel-practical-technique
#18
Jing-Wen Gong, Jun-Hao Chen, Ting Shen, Jin Jiang
PURPOSE: To introduce a novel practical technique of self-made cryopreservative fibrin glue (SMC) applied in pterygium surgery and to assess its safety and efficacy. METHODS: Forty-eight eyes of 48 patients with nasal primary pterygium were enrolled. The patients were equally assigned to 6 groups. Self-made fibrin glue was subpackaged and, respectively, cryopreserved for 3, 7, 15 days and 1, 2 and 3 months. At each time point, the asepsis of SMC was confirmed by bacterial culture and colony counting...
July 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28672976/suncon-medical-adhesive-is-a-suitable-alternative-to-fibrin-glue-in-the-23g-minimally-invasive-vitrectomy
#19
Sha Liu, Suyan Li, Zhengpei Zhang, Sujuan Ji, Haiyang Liu
Fibrin glue is frequently used to close the incision of the sclera and conjunctiva. However, its use is limited due to its blood-borne origins. The study evaluated the suitability of Suncon medical adhesive as a replacement for fibrin glue in 23G minimally invasive vitrectomy as an animal study. One eye of Japanese white rabbits (total, 18 rabbits) received an intravitreal injection of 0.05 ml of Suncon medical adhesive, while the other eye was injected with 0.05 ml of saline and served as the control eye. Slit lamp, indirect ophthalmoscope and electroretinogram (ERG) examinations were carried out before and 28 days after the interventions...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28657463/transplantation-of-human-dental-pulp-derived-stem-cells-or-differentiated-neuronal-cells-from-human-dental-pulp-derived-stem-cells-identically-enhances-regeneration-of-the-injured-peripheral-nerve
#20
Imran Ullah, Ju-Mi Park, Young-Hoon Kang, June-Ho Byun, Dae-Geon Kim, Joo-Heon Kim, Dong-Ho Kang, Gyu-Jin Rho, Bong-Wook Park
Human dental mesenchymal stem cells isolated from the dental follicle, pulp, and root apical papilla of extracted wisdom teeth have been known to exhibit successful and potent neurogenic differentiation capacity. In particular, human dental pulp-derived stem cells (hDPSCs) stand out as the most prominent source for in vitro neuronal differentiation. In this study, to evaluate the in vivo peripheral nerve regeneration potential of hDPSCs and differentiated neuronal cells from DPSCs (DF-DPSCs), a total of 1 × 10(6) hDPSCs or DF-hDPSCs labeled with PKH26 tracking dye and supplemented with fibrin glue scaffold and collagen tubulization were transplanted into the sciatic nerve resection (5-mm gap) of rat models...
July 25, 2017: Stem Cells and Development
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