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Fibrin glue

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https://www.readbyqxmd.com/read/28319418/autologous-cartilage-chip-transplantation-improves-repair-tissue-composition-compared-with-marrow-stimulation
#1
Bjørn Borsøe Christensen, Morten Lykke Olesen, Martin Lind, Casper Bindzus Foldager
BACKGROUND: Repair of chondral injuries by use of cartilage chips has recently demonstrated clinical feasibility. PURPOSE: To investigate in vivo cartilage repair outcome of autologous cartilage chips compared with marrow stimulation in full-thickness cartilage defects in a minipig model. STUDY DESIGN: Controlled laboratory study. METHODS: Six Göttingen minipigs received two 6-mm chondral defects in the medial and lateral trochlea of each knee...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28303204/removal-of-a-malignant-cystic-brain-tumor-utilizing-pyoktanin-blue-and-fibrin-glue-technical-note
#2
Nobuhide Hayashi, Takahiro Sasaki, Nagatsuki Tomura, Hideo Okada, Toshikazu Kuwata
BACKGROUND: The leakage of cystic fluid during metastatic cystic brain tumor resection may cause tumor dissemination. When the cyst wall is thin, excision without removing the wall is often difficult. METHODS: We were able to perform an en bloc resection of a cystic malignant brain tumor after aspirating the cystic fluid, injecting pyoktanin blue into the cyst to stain the cyst walls, and solidifying the empty cyst cavity by filling it with fibrin glue. RESULTS: Pyoktanin blue readily stained the thin cystic walls and enabled visualization of mural damage...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28299263/clinical-evaluation-of-coverage-of-open-wounds-polyglycolic-acid-sheet-with-fibrin-glue-spray-vs-split-thickness-skin
#3
Yumi Mochizuki, Hirofumi Tomioka, Fumihiko Tushima, Hiroaki Shimamoto, Hideaki Hirai, Yuu Oikawa, Hiroyuki Harada
PURPOSE: This study aimed to evaluate the coverage of oral wounds using either a polyglycolic acid (PGA) sheet or split-thickness skin grafting (STSG). MATERIALS AND METHODS: A total of 119 cases of wound coverage using a PGA sheet and fibrin glue spray as well as 132 cases of wound coverage cases using STSG were reviewed retrospectively. The site of the excision area, perioperative conditions, and postoperative functional problems were evaluated. RESULTS: The PGA group had significantly shorter operation time, earlier start of oral intake, and shorter hospitalization than the STSG group...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28291954/therapeutic-mechanisms-of-human-adipose-derived-mesenchymal-stem-cells-in-a-rat-tendon-injury-model
#4
Sang Yoon Lee, Bomi Kwon, Kyoungbun Lee, Young Hoon Son, Sun G Chung
BACKGROUND: Although survival of transplanted stem cells in vivo and differentiation of stem cells into tenocytes in vitro have been reported, there have been no in vivo studies demonstrating that mesenchymal stem cells (MSCs) could secrete their own proteins as differentiated tenogenic cells. Purpose/Hypothesis: Using a xenogeneic MSC transplantation model, we aimed to investigate whether MSCs could differentiate into the tenogenic lineage and secrete their own proteins. The hypothesis was that human MSCs would differentiate into the human tenogenic lineage and the cells would be able to secrete human-specific proteins in a rat tendon injury model...
March 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28277417/comparison-of-healing-intra-articular-fracture-of-distal-femur-using-a-kirschner-wire-and-autologous-fibrin-glue-in-an-animal-model
#5
Mohammad R Azarpira, Kasra Vazani, Maryam Ayatollahi, Negar Azarpira, Maryam Kaviani
Considering different surgical techniques for the fixation of osteochondral intra-articular fracture, the present study aimed to compare the efficacy of autologous fibrin glue and Kirschner wire (KW) on an osteochondral fracture in the left lateral condyle of Dutch rabbits with a control group. After 6 weeks, macroscopic and microscopic evaluation showed that autologous fibrin glue is easier and faster with a higher number of bone trabecula (P<0.05), whereas the healing rate and cellularity of the healing site were not different between the two groups (KW and glue)...
March 8, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28268263/endoscopic-management-of-gastrointestinal-leaks-and-perforation-with-polyglycolic-acid-sheets
#6
Sojung Han, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
Gastrointestinal (GI) leakage, fistulae, and perforations can be serious and life threatening. There has been a paradigm shift in the management approach of these conditions, from surgical to conservative, including endoscopic management. Here, we report two cases of endoscopic closure of a GI fistula and perforation using polyglycolic acid (PGA) sheets with fibrin glue. The first case is of an anastomotic leak detected after subtotal gastrectomy with gastroduodenostomy. After failed application of endoclips, a PGA sheet was applied, and the fistula was successfully closed...
March 8, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28261700/fibrin-glue-infiltrating-hemostasis-for-intractable-bleeding-from-the-liver-or-spleen-during-liver-transplantation
#7
Shin Hwang, Dong-Hwan Jung, Gi-Won Song, Tae-Yong Ha, Eun-Kyeong Jwa, Sung-Gyu Lee
Portal hypertension induces congestion of the liver and spleen, thus any capsular or parenchymal injury to these organs can produce intractable bleeding which generally is not easily controlled. To cope with intractable bleeding such as being encountered during liver transplantation, we developed an infiltrating hemostasis technique as a conceptual shift from conventional application methods, in which fibrin glue is locally injected into the bleeding area on the liver or spleen. This technique, which uses a fibrin glue kit (2 ml kit; Greenplast, Green Cross, Seoul, Korea), consists of inserting the needle 0...
November 2016: Ann Hepatobiliary Pancreat Surg
https://www.readbyqxmd.com/read/28257949/retractorless-surgery-for-third-ventricle-tumor-resection-through-the-transcallosal-approach
#8
Xiang Wang, Yan-Hui Liu, Qing Mao
OBJECTIVE: Resection of tumors of the third ventricle through the transcallosal-interforniceal approach presents a surgical challenge with potential serious postoperative neurological deficits and complications. Retraction injury of the deep brain tissue and veins is a possible reason. Here, we aimed to investigate the feasibility and value of retractorless surgery in third ventricle tumor resection. PATIENTS AND METHODS: Since 2014, a total of 31 patients with third ventricle tumors were operated in our institution...
February 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28254539/video-is-part-of-the-ms-three-layer-reconstruction-with-iliotibial-tract-after-endoscopic-resection-of-sinonasal-tumors-technical-note
#9
Davide Mattavelli, Alberto Schreiber, Marco Ferrari, Remo Accorona, Andrea Bolzoni Villaret, Paolo Battaglia, Paolo Castelnuovo, Piero Nicolai
INTRODUCTION: Watertight reconstruction to separate the intradural compartment from the sinonasal cavities is crucial after endoscopic resection with transnasal craniectomy (ERTC) for naso-ethmoidal tumors. Three-layer reconstruction with the iliotibial tract (TRITT) is a safe and reliable alternative when vascularized flaps are not available. SURGICAL TECHNIQUE: The iliotibial tract graft is harvested on the lateral aspect of the thigh and divided in three portions, which are positioned in a multi-layered fashion to close the skull base defect...
February 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28250774/a-giant-lumbar-pseudomeningocele-in-a-patient-with-neurofibromatosis-type-1-a-case-report
#10
Mauro Dobran, Maurizio Iacoangeli, Paolo Ruscelli, Martina Della Costanza, Davide Nasi, Massimo Scerrati
This is a rare case of giant lumbar pseudomeningocele with intra-abdominal extension in patient with neurofibromatosis type 1 (NF1). The patient's clinical course is retrospectively reviewed. A 34-year-old female affected by NF1 was referred to our institution for persistent low back pain and MRI diagnosis of pseudomeningocele located at L3 level with paravertebral extension. From the first surgical procedure by a posterior approach until the relapse of the pseudomeningocele documented by MRI, the patient underwent two subsequent posterior surgical procedures to repair the dural sac defect with fat graft and fibrin glue...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28249342/fibrin-glue-minocycline-combination-as-a-sustained-release-for-the-prevention-of-postoperative-alveolar-air-leak-in-thoracoscopic-lung-resections
#11
Hideki Kawai
Although the ultrasonic scalpel is known to avoid inadvertent thermal injury to pulmonary parenchyma owing to its lower tip temperature, there are reports suggesting late onset postoperative alveolar air leakage by using it. Herein, a novel method of preventing postoperative air leakage was developed by using a sustained release system of fibrin glue-minocycline combination. This method ensures that the effect of fibrin glue is followed by the effect of minocycline, which functions as a sustained release formulation...
March 1, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28217677/delayed-hemorrhage-effect-of-local-anesthesia-with-epinephrine-in-the-loop-electrosurgical-excisional-procedure
#12
Yong Jae Lee, Yunjin Park, In Ok Lee, Jung Won Yoon, Jung Yoon Lee, Sang Wun Kim, Sunghoon Kim, Young Tae Kim, Eun Ji Nam
OBJECTIVE: The aim of this study was to investigate factors preventing delayed hemorrhage after the loop electrosurgical excisional procedure (LEEP). METHODS: Medical records of patients who underwent LEEP at one university affiliated hospital from October 2013 to January 2015 were reviewed. Patients with or without delayed hemorrhage were classified. LEEP was performed either in an operating room under general anesthesia or in a procedure room with local anesthesia in the outpatient clinic...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28215637/polyglycolic-acid-sheet-attached-with-fibrin-glue-can-facilitate-faster-epithelialization-of-the-mastoid-cavity-after-canal-wall-down-tympanoplasty
#13
Taisuke Kobayashi, Kiyofumi Gyo, Masahiro Komori, Masamitsu Hyodo
OBJECTIVE: This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly-N-acetyl-glucosamine (Kichin) sheet. MATERIALS AND METHODS: After completion of the CWD tympanoplasty, PGA sheet (n=16, PGA group) with fibrin glue or Kichin sheet (n=38, Kichin group) were placed on the bone surface of the mastoid bowl...
February 16, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28210623/in-vitro-and-in-vivo-evaluation-of-commercially-available-fibrin-gel-as-a-carrier-of-alendronate-for-bone-tissue-engineering
#14
Beom Su Kim, Feride Shkembi, Jun Lee
Alendronate (ALN) is a bisphosphonate drug that is widely used for the treatment of osteoporosis. Furthermore, local delivery of ALN has the potential to improve the bone regeneration. This study was designed to investigate an ALN-containing fibrin (fibrin/ALN) gel and evaluate the effect of this gel on both in vitro cellular behavior using human mesenchymal stem cells (hMSCs) and in vivo bone regenerative capacity. Fibrin hydrogels were fabricated using various ALN concentrations (10(-7)-10(-4 )M) with fibrin glue and the morphology, mechanical properties, and ALN release kinetics were characterized...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28210022/csf-related-complications-after-intradural-spinal-tumor-surgery-utility-of-an-autologous-fat-graft
#15
Kenan I Arnautovic, Marko Kovacevic
OBJECT: The incidence of cerebrospinal fluid (CSF)-related complications after intradural spinal tumor (IST) surgery is high and reported in up to 18% of patients. However, no efficient way to prevent those complications has been reported so far. Treating these complications may require prolonged bed rest, re-exploration, external lumbar drain, use of antibiotics, and possible precipitation of other complications. To alleviate the risk of CSF-related complications, we prospectively adopted the intraoperative use of autologous fat grafting after IST surgery...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28203557/inhibitory-effect-of-sustained-perivascular-delivery-of-paclitaxel-on-neointimal-hyperplasia-in-the-jugular-vein-after-open-cutdown-central-venous-catheter-placement-in-rats
#16
Seongyup Kim, Younglim Kim, Ji Woong Hwang, Suk-Bae Moon
PURPOSE: Inhibitory effect of paclitaxel on neointimal hyperplasia after open cutdown has not been elucidated. METHODS: For the control group (n = 16), silicone 2.7-Fr catheters were placed via the right external jugular vein with the cutdown method. For the treatment group (n = 16), a mixture of 0.65 mg of paclitaxel and 1 mL of fibrin glue was infiltrated around the exposed vein after cutdown. After scheduled intervals (1, 2, 4, and 8 weeks), the vein segment was harvested and morphometric analysis was performed on cross-sections...
February 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28202253/flap-fixation-using-tissue-glue-or-sutures-appears-to-reduce-seroma-aspiration-after-mastectomy-for-breast-cancer
#17
James van Bastelaar, Lotte L B Theunissen, Maarten G J Snoeijs, Geerard L Beets, Yvonne L J Vissers
BACKGROUND: Up to 90% of patients undergoing breast cancer surgery suffer from seroma formation, which can cause discomfort and various complications after mastectomy. This retrospective observational cohort study aimed to elucidate whether flap fixation with fibrin sealant (ARTISS) tissue glue reduces seroma formation and seroma aspiration after mastectomy when compared with flap fixation using Vicryl sutures and when compared with a conventional wound closure technique. METHODS: All patients undergoing mastectomy due to invasive breast cancer or ductal carcinoma in situ were eligible for inclusion...
January 24, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28181448/efficacy-of-bubaline-fibrin-glue-on-full-thickness-pinch-and-punch-skin-grafting-in-a-pig
#18
Krittee Dejyong, Theerayuth Kaewamatawong, Pasakorn Brikshavana, Sumit Durongphongtorn
Fibrin glue, which is formed from the action of thrombin (a serine protease) on fibrinogen, has been developed for use as an adhesive to increase the success of skin graft surgery. The objective of this study was to evaluate if bubaline fibrin glue would promote skin graft survival in pigs. The grafting was divided into two steps. First, granulation wound preparation was performed in a healthy swine by creating four full-skin depth wounds (3 × 12 cm(2)) at the dorsal part of the loin area on each side...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28170080/mesh-fixation-with-glue-versus-suture-for-chronic-pain-and-recurrence-in-lichtenstein-inguinal-hernioplasty
#19
REVIEW
Ping Sun, Xiang Cheng, Shichang Deng, Qinggang Hu, Yi Sun, Qichang Zheng
BACKGROUND: Chronic pain following mesh-based inguinal hernia repair is frequently reported, and has a significant impact on quality of life. Whether mesh fixation with glue can reduce chronic pain without increasing the recurrence rate is still controversial. OBJECTIVES: To determine whether tissue adhesives can reduce postoperative complications, especially chronic pain, with no increase in recurrence rate, compared with sutures for mesh fixation in Lichtenstein hernia repair...
February 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28162204/-evidence-based-clinical-practice-guidelines-for-the-treatment-of-dural-tears-and-the-consequent-cerebrospinal-fluid-leak-during-spine-surgery
#20
(no author information available yet)
Dural tears (DT) and the consequent cerebral spinal fluid (CSF) leak are not rare in spine surgeries. CSF leak can be troublesome, leading to pseudomeningocele, cutaneous CSF fistula, and meningitis. Revision surgery is unavoidable in some cases. The reported incidences of DT and CSF leak are different according to the various pathologies. Ossification of the posterior longitudinal ligament, revision spine surgery and multi-segment laminectomy have higher risks for DT. Various techniques have been described to manage this complication, such as bed rest, repair with dural substitutes, fibrin glue, gelatin sponge, lumbar drain, muscle flap, etc...
February 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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