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Fibrin glue

Dvir Froylich, Matthew Davis, Gautam Sharma, Tammy Fouse, Philip Schauer, Stacy Brethauer
BACKGROUND: Gastrojejunostomy revision after gastric bypass surgery is a challenging procedure that requires advanced skills. The air-leak test was performed to identify gastrojejunostomy leaks. Omental patch seal technique is a well-known treatment of perforated gastrojejunostomy ulcers (Surg Obes Relat Dis 4:423-8, 2012; Surg Endosc 2:384-9, 2013; Surg Endosc 11:2110, 2007). METHODS: We present a case of a 40-year-old female, who underwent laparoscopic gastric bypass 6 years prior and subsequently developed marginal ulcer, resulting in chronic gastrojejunostomy stricture...
June 18, 2018: Obesity Surgery
Elke Tieftrunk, Ihsan Ekin Demir, Stephan Schorn, Mine Sargut, Florian Scheufele, Lenika Calavrezos, Rebekka Schirren, Helmut Friess, Güralp O Ceyhan
BACKGROUND: Pancreatic fistula/PF is the most frequent and feared complication after distal pancreatectomy/DP. However, the safest technique of pancreatic stump closure remains an ongoing debate. Here, we aimed to compare the safety of different pancreatic stump closure techniques for preventing PF during DP. METHODS: We performed a PRISMA-based meta-analysis of all relevant studies that compared at least two techniques of stump closure during DP with regard to PF rates/PFR...
2018: PloS One
Ahmad Assalia, Anat Ilivitzki, Amos Ofer, Alain Suissa, Elias Manassa, Ahmad Mahajna, Iyad Khamaysi
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is considered as a first line treatment for morbid obesity around the globe. Leakage and subsequent gastric fistula is the most dreadful complication, which may lead to serious morbidity and even mortality. OBJECTIVES: To assess the safety and efficacy of fibrin glue application in the setting of gastric fistula after LSG. SETTING: University hospital, Israel. METHODS: Twenty-four morbidly obese patients (mean age = 42...
April 22, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
António Bernardes, Catarina Melo, Sandra Ferraz
INTRODUCTION: Postoperative duodenal-cutaneous fistula represents a rare and very complex problem. In most cases operative management becomes necessary, but only after local and systemic stabilization and sepsis control. CASE PRESENTATION: A 39-year-old man was admitted for surgical management of laparostomy and pyloro-duodenostomy of the first (DI) and second (DII) duodenal segments with one year of evolution, as a complication of several surgical interventions...
June 4, 2018: International Journal of Surgery Case Reports
M Jane Brennan, Sydney E Hollingshead, Jonathan J Wilker, Julie C Liu
Many protein-based materials, such as soy and mussel adhesive proteins, have been the subject of scientific and commercial interest. Recently, a variety of protein adhesives have been isolated from diverse sources such as insects, frogs and squid ring teeth. Many of these adhesives have similar amino acid compositions to elastomeric proteins such as elastin. Although elastin is widely investigated for a structural biomaterial, little work has been done to assess its adhesive potential. In this study, recombinant elastin-like polypeptides were created to probe the factors affecting adhesion strength...
May 2018: Royal Society Open Science
Ho Sik Hwang, Kyong Jin Cho, Gabriel Rand, Roy S Chuck, Ji Won Kwon
BACKGROUND: In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of recurrence and otheradverse events. METHODS: Retrospective chart review of 78 consecutive patients with stage III primary pterygia who underwent an optimal excision technique by three experienced surgeons...
June 7, 2018: BMC Ophthalmology
Sathyadeepak Ramesh, Alexander Nobori, Yi Wang, Daniel Rootman, Robert Alan Goldberg
PURPOSE: To test the hypothesis that the orbit expands in the cranial vault after wide dural exposure after minimally invasive extradural transorbital decompression for thyroid eye disease. METHODS: A cross-sectional cohort study of 36 patients (60 orbits). Preoperative and postoperative (6 months) orbital CT following extradural transorbital decompression was analyzed. Primary outcome measure was the percentage area of the cranial vault occupied by orbital and brain tissue in a predefined window before and after surgery...
June 6, 2018: Ophthalmic Plastic and Reconstructive Surgery
Evelyn P Murphy, Christopher Fenelon, Niall P McGoldrick, Stephen R Kearns
Osteochondral lesions of the talus refer to a chondral or subchondral defect of the articular cartilage and potentially the underlying bone. Ankle sprains are an extremely common injury; approximately 27,000 ankle sprains occur per day in America. Fifty percent of these can lead to a cartilage injury to the ankle. There has been a high quoted rate of failure with conservative measures of up to 45% in some series. Surgical options are largely broken down into 2 groups, namely, reparative or regenerative treatments...
April 2018: Arthroscopy Techniques
Yanling Zhou, Long Gao, Jinliang Peng, Min Xing, Yan Han, Xiaoya Wang, Yuhong Xu, Jiang Chang
In this study, a novel Bioglass/albumin composite hydrogel with controllable injectability, good adhesiveness, and bioactivity, is developed by utilizing dual-functional bioactive ions released from Bioglass, which on one side controls the gelling time by creating an alkaline environment to regulate the cross-linking reaction between human serum albumin and succinimidyl succinate modified poly(ethylene glycol), and on the other side stimulates wound healing. The composite hydrogel exhibits adhesive property that is superior to clinically used fibrin and cyanoacrylate glues...
May 29, 2018: Advanced Healthcare Materials
Kazushi Fukagawa, Satoshi Ono, Kazuhiko Koike
Takimoto et al1 first reported a novel endoscopic tissue shielding method using polyglycolic acid sheets (PGA) and fibrin glue in 2012. Since that time, it has been reported to be a safe and effective method to prevent complications after endoscopic submucosal dissection (ESD)2, 3 ; however more data is needed regarding associated adverse events. This article is protected by copyright. All rights reserved.
May 30, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Davide Borroni, Bogumil Wowra, Vito Romano, Maria Boyadzhieva, Diego Ponzin, Stefano Ferrari, Sajjad Ahmad, Mohit Parekh
Simple limbal epithelial transplant (SLET) is a recently developed technique for treating limbal stem cell deficiency (LSCD) caused by ocular burns. A small limbal biopsy from the donor eye, usually from the patient's healthy eye, is excised and dissected into multiple pieces. An amniotic membrane is patched using fibrin glue on the diseased eye after removing the conjunctivalized pannus from the corneal surface. The limbal biopsy pieces are placed onto the amniotic membrane, fixed with fibrin glue followed by bandaging of the ocular surface with a contact lens...
May 22, 2018: Survey of Ophthalmology
Yuanzheng Zhu, Yangyan Yi, Shuifa Yang, Jing Zhang, Shu Wu, Zhaohui Wang
Objective: To discuss the possibility of constructing injectable tissue engineered adipose tissue, and to provide a new approach for repairing soft tissue defects. Methods: Human adipose-derived stem cells (hADSCs) were extracted from the lipid part of human liposuction aspirate by enzymatic digestion and identified by morphological observation, flow cytometry, and adipogenic induction. The hADSCs underwent transfection by lentivirus vector expressing hepatocyte growth factor and green fluorescent protein (HGF-GFP-LVs) of different multiplicity of infection (MOI, 10, 30, 50, and 100), the transfection efficiency was calculated to determine the optimum MOI...
September 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
C G F Nganga Ngabou, C Makita, S S Ndalla, F Nkokolo, R Messe Ambia Koulimaya, B Diatewa
INTRODUCTION: Pterygium surgery is marked by the possibility of recurrences; one of the techniques which results in the least recurrences is conjunctival autograft. Fixation of the conjunctiva had traditionally been accomplished with sutures. In recent years, conjunctival grafting has also been performed with fibrin glue. Even more recently, with a view towards improving the quality of postoperative results, some surgeons recommend the use of autologous blood. This study aims to evaluate the stability of this latest method of graft fixation, while assessing its postoperative results...
May 15, 2018: Journal Français D'ophtalmologie
Toshiki Tanaka, Kazuhiro Ueda, Junichi Murakami, Kimikazu Hamano
Prolonged postoperative air leaks are associated with extended periods of postoperative hospitalization, increased hospital costs, and an increased incidence of major cardiopulmonary complications. To prevent prolonged air leaks, we used small pieces of polyglycolic acid mesh as a pledget during the stitching of air leak sites. The stitched sites were then covered with mesh and fibrin glue. This novel technique showed the highest airway pressure tolerance in an ex vivo experimental study. There were no incidents of prolonged air leak among the five clinical cases in which this technique was initially applied...
May 15, 2018: Annals of Thoracic Surgery
Yusuf Kenan Daglioglu, Ozgul Duzgun, Inanc Samil Sarici, Kemal Turker Ulutas
PURPOSE: To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing. METHODS: Thirty six Wistar-Albino male rats diveded into 3 groups according to control(Group1), PRP (Group 2) and fibrin glue(Tisseel VH) (Group 3). The colon was transected with scissor and subsequently an end to end anastomosis was performed using continuous one layer 6/0 vicryl sutures. Postoperative 7th day effect of anastomotic healing measuring with tissue hydroxyproline(TH) level and anastomotic bursting pressure(ABP); moreover comparison of cytokine (IL-6 and IL-10) and procalcitonin levels on 1st,3rd and 7th days...
April 2018: Acta Cirúrgica Brasileira
Ana Cláudia Viana Wanzeler, Bruna Duarte, Vitor Duarte Moron de Andrade, Monica Alves
Purpose: Pterygium is a fibrovascular condition of the ocular surface that can cause a broad range of irritative and visual symptoms. Controversy exists regarding pterygium mechanisms, management, surgical techniques, adjuvant approaches and impact on patients' quality of life. We performed a retrospective survey focused on the impact of pterygium-related symptoms before surgery and patients' satisfaction after excision surgery followed by conjunctival autograft transplantation with fibrin glue, based on patients' subjective reporting...
2018: Clinical Ophthalmology
Yichao Han, Su Yang, Wei Huang, Zhongmin Wang, Hecheng Li
We present the case of a fistula between the trachea and the esophagogastric anastomosis in a 58-year-old male after esophagectomy. A Hem-o-Lok clip used at the time to ligate the azygos vein was discovered by esophagoscopy and bronchoscopy to be eroding into the both structures. A covered self-expandable Y-shaped metallic tracheobronchial stent was customized with a 3D printed airway model and inserted in place, with endoscopic injection of fibrin glue to the anastomotic site. 64 days after implantation, the stent was withdrawn with complete healing of the fistula...
May 12, 2018: Annals of Thoracic Surgery
İsmail Okan Yildirim, Turgut Pişkin, Enes Duman, Ali Firat, Murat Dogan, Hülya Taskapan, Idris Sahin, Kaya Sarac
BACKGROUND: We aimed to evaluate the efficacy of percutaneous embolization following lymphangiography using C-arm cone-beam computed tomography (CBCT) performed at the site of lymphatic leakage in patients with postrenal transplant lymphocele. METHODS: Between July 2014 and August 2017, 13 patients not responding to percutaneous ethanol sclerotherapy and conservative treatment for recurrent lymphocele following renal transplant were included. The mean age of the patients was 56...
May 11, 2018: Transplantation
Branden W Luna, Luca Paoletti, Chadrick E Denlinger, Nicholas J Pastis, Timothy P Whelan
Airway complications following lung transplantation are well described and can lead to significant morbidity and mortality. Treatment options for anastomotic dehiscence include expectant management, placement of endobronchial stents, or surgical repair. The use of fibrin sealant instilled via bronchoscopy to seal a dehiscence has not been well described. Our patient is a 57 year old male who underwent orthotropic bilateral lung transplantation for end stage COPD. He was found to have a partial bronchial anastomosis dehiscence and subsequently treated with endobronchial fibrin sealant glue instillation...
May 5, 2018: Annals of Thoracic Surgery
Li-Hua Chen, Hong-Tian Zhang, Ru-Xiang Xu, Li Zhang, Wen-De Li, Kai Sun
Most patients diagnosed with neurofibromatosis type 2 (NF2) have bilateral vestibular schwannomas (VS). Through reviewing surgical method and clinical outcomes, we tried to find out a strategy for treatments in NF2 patients with VS.We retrospectively reviewed patients diagnosed pathological NF2 and have had microsurgery (MS) for VS in the PLA Army General Hospital. Seventeen patients were included from January 2000 to December 2016. Fifteen patients had progressive hearing impairment, and 7 ears were totally deaf...
April 2018: Medicine (Baltimore)
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