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Fibrin glue

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https://www.readbyqxmd.com/read/29665286/a-strategy-for-rapid-construction-of-blood-vessel-like-structures-with-complex-cell-alignments
#1
Nuoxin Wang, Yunhu Peng, Wenfu Zheng, Lixue Tang, Shiyu Cheng, Junchuan Yang, Shaoqin Liu, Wei Zhang, Xingyu Jiang
A method is developed that can rapidly produce blood vessel-like structures by bonding cell-laden electrospinning (ES) films layer by layer using fibrin glue within 90 min. This strategy allows control of cell type, cell orientation, and material composition in separate layers. Furthermore, ES films with thicker fibers (polylactic-co-glycolic acid, fiber diameter: ≈3.7 µm) are used as cell-seeding layers to facilitate the cell in-growth; those with thinner fibers (polylactic acid, fiber diameter: ≈1.8 µm) are used as outer reinforcing layers to improve the mechanical strength and reduce the liquid leakage of the scaffold...
April 17, 2018: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29657982/epithelial-ingrowth-following-laser-in-situ-keratomileusis-lasik-prevalence-risk-factors-management-and-visual-outcomes
#2
REVIEW
Darren Shu Jeng Ting, Sathish Srinivasan, Jean-Pierre Danjoux
The number of laser in situ keratomileusis (LASIK) procedures is continuing to rise. Since its first application for correcting simple refractive errors over 25 years ago, the role of LASIK has extended to treat other conditions, including postkeratoplasty astigmatism/ametropia, postcataract surgery refractive error and presbyopia, among others. The long-term effectiveness, predictability and safety have been well established by many large studies. However, due to the creation of a potential interface between the flap and the underlying stroma, interface complications such as infectious keratitis, diffuse lamellar keratitis and epithelial ingrowth may occur...
2018: BMJ open ophthalmology
https://www.readbyqxmd.com/read/29651386/tissue-engineering-in-maxillary-bone-defects
#3
Azizollah Khodakaram-Tafti, Davood Mehrabani, Hanieh Shaterzadeh-Yazdi, Barbad Zamiri, Mahsa Omidi
BACKGROUND: Restoration of craniofacial bone defects has been a concern for oral and maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared with autologous bone graft in mandibular defects of rabbit. METHODS: Bilateral unicortical osteotomy was performed in the diastema region of 10 male Dutch rabbits. The subjects were randomly divided into 2 equal groups. The mandibular defect on the right side was treated with fibrin glue scaffold and the defect on the left side with autologous bone graft provided from iliac crest...
January 2018: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/29644328/techniques-for-ovarian-tissue-transplantation-and-results
#4
Jacques Donnez, Diego D Manavella, Marie-Madeleine Dolmans
Fertility preservation has emerged as a field of growing interest thanks to increasingly effective cancer treatments in women. For young women with good prospects of surviving cancer, fertility preservation counseling before gonadotoxic treatment is imperative to offer them a potential chance of future childbearing. Ovarian tissue cryopreservation and transplantation rises as a strategy for fertility preservation, especially for prepubertal girls, adolescents and women in whom cancer treatment cannot be delayed...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29643713/modified-conjunctival-flap-as-a-primary-procedure-for-nontraumatic-acute-corneal-perforation
#5
Yi-Chen Sun, Jason P Kam, Tueng T Shen
Objective: Appropriate management of nontraumatic acute corneal perforation is always a challenge even with the many advances in surgical materials and techniques. We reported the outcomes of a case series of acute corneal perforation repair using a newly modified conjunctival flap with amniotic membrane transplant (AMT), fibrin glue, and a bandage soft contact lens (BCL). Materials and Methods: A total of 13 consecutive referral cases with nontraumatic acute corneal perforation at the University of Washington were reviewed...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29582809/concomitant-use-of-conjunctival-tissue-graft-from-the-pterygium-itself-without-rotation-in-pterygium-surgery-a-full-circle-in-conjunctival-autografting
#6
Shreesha Kumar Kodavoor, Nitin Narendra Tiwari, Dandapani Ramamurthy
Purpose: The aim of this study is to describe a modified technique of using conjunctival tissue from the pterygium itself without any rotation of graft for the primary pterygium in eyes with glaucoma filtering bleb, glaucoma suspects, and in primary double-head pterygium using fibrin glue. Methods: In this retrospective, noncomparative, interventional case series, 98 eyes of 98 patients with primary pterygium operated between July 2011 to July 2016 were included...
April 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29581352/surgical-adhesives-in-ophthalmology-history-and-current-trends
#7
REVIEW
Samantha Guhan, Si-Liang Peng, Hrag Janbatian, Stephanie Saadeh, Stephen Greenstein, Faisal Al Bahrani, Ali Fadlallah, Tsai-Chu Yeh, Samir A Melki
Tissue adhesives are gaining popularity in ophthalmology, as they could potentially reduce the complications associated with current surgical methods. An ideal tissue adhesive should have superior tensile strength, be non-toxic and anti-inflammatory, improve efficiency and be cost-effective. Both synthetic and biological glues are available. The primary synthetic glues include cyanoacrylate and the recently introduced polyethylene glycol (PEG) derivatives, while most biological glues are composed of fibrin...
March 26, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29567870/-blister-like-aneurysm-originating-from-the-anterior-communicating-artery-a-case-report
#8
Tomohiro Abiko, Katsuya Saito, Makoto Murase, Hideyuki Tomita
Blister-like aneurysms(BLA)are morphologically thin-walled fragile structures that are associated with a high risk of intraoperative rupture. BLAs presumably originate from an arterial dissection and often stem from a non-branching site on the supraclinoid segment of the internal carotid artery. We report a rare case of a patient who was successfully treated for a ruptured BLA originating from the anterior communicating artery(Acom). A 60-year-old woman presented with severe headache and loss of consciousness...
March 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29555464/development-of-tannin-inspired-antimicrobial-bioadhesives
#9
Jinshan Guo, Wei Sun, Jimin Peter Kim, Xili Lu, Qiyao Li, Min Lin, Oliver Mrowczynski, Elias B Rizk, Juange Cheng, Guoying Qian, Jian Yang
Tissue adhesives play an important role in surgery to close wounds, seal tissues, and stop bleeding, but existing adhesives are costly, cytotoxic, or bond weakly to tissue. Inspired by the water-resistant adhesion of plant-derived tannins, we herein report a new family of bioadhesives derived from a facile, one-step Michael addition of tannic acid and gelatin under oxidizing conditions and crosslinked by silver nitrate. The oxidized polyphenol groups of tannic acid enable wet tissue adhesion through catecholamine-like chemistry, while both tannic acid and silver nanoparticles reduced from silver nitrate provide antimicrobial sources inherent within the polymeric network...
March 16, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29551726/watertight-dural-closure-in-pediatric-craniotomies-is-it-really-necessary
#10
Jonathan Roth, Haggai Benvenisti, Shlomi Constantini
BACKGROUND: Dural closure following intracranial procedures is considered crucial to reduce postoperative complications such as pseudomeningoceles (PM), CSF leaks, hydrocephalus, and infections. However, watertight dural closure (WTDC) is often difficult to achieve, and dural substitutes are often used. We describe our experience with non-WTDC in children. METHODS: Data was collected retrospectively. Redo and craniectomy cases were excluded. Collected data included demographics, surgical etiology, various radiological parameters, ventricular opening, usage of drains and shunts, dural closure technique, and complications...
March 15, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29533334/application-of-regenerative-treatment-for-tympanic-membrane-perforation-with-cholesteatoma-tumor-or-severe-calcification
#11
Shin-Ichi Kanemaru, Rie Kanai, Misaki Yoshida, Yuji Kitada, Kaoru Omae, Shigeru Hirano
OBJECTIVE: To apply regenerative treatment for tympanic membrane (TM) perforation to patients with severe calcification of the TM, cholesteatomas, or tumors localized to the tympanic cavity. STUDY DESIGN: Controlled clinical pilot study. SETTING: General hospitals. PATIENTS: Forty-five patients (age: 8-85; M = 19, F = 26) were selected from patients with or without TM perforation for the regenerative treatment...
April 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29524461/endolymphatic-interventions-for-the-treatment-of-chylothorax-and-chylous-ascites-in-neonates-technical-and-clinical-success-and-complications
#12
Rajiv N Srinivasa, Jeffrey Forris Beecham Chick, Joseph J Gemmete, Anthony N Hage, Ravi N Srinivasa
INTRODUCTION: To report the technical and clinical success of performing minimally invasive endolymphatic embolization in neonates presenting with a chylothorax or chylous ascites. MATERIALS AND METHODS: 3 neonates, 2 males and 1 female, with a mean age of 28 days (range: 19-39 days) presented with a chylothorax (2) or chylous ascites (1) which was refractory to conservative management. All 3 patients (1 previously reported) underwent intranodal lymphangiography followed by thoracic duct embolization with 1 patient undergoing additional sclerosis of the retroperitoneal abdominal lymphatics...
March 7, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29497572/engraftment-neuroglial-transdifferentiation-and-behavioral-recovery-after-complete-spinal-cord-transection-in-rats
#13
Luzzi Sabino, Crovace Alberto Maria, Lacitignola Luca, Valentini Valerio, Francioso Edda, Rossi Giacomo, Invernici Gloria, Galzio Renato Juan, Crovace Antonio
Background: Proof of the efficacy and safety of a xenogeneic mesenchymal stem cell (MSCs) transplant for spinal cord injury (SCI) may theoretically widen the spectrum of possible grafts for neuroregeneration. Methods: Twenty rats were submitted to complete spinal cord transection. Ovine bone marrow MSCs, retrovirally transfected with red fluorescent protein and not previously induced for neuroglial differentiation, were applied in 10 study rats (MSCG). Fibrin glue was injected in 10 control rats (FGG)...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29487867/reduction-of-pulmonary-air-leaks-with-a-combination-of-polyglycolic-acid-sheet-and-alginate-gel-in-rats
#14
Mari Matoba, Toshitaka Takagi, Hiroyuki Tsujimoto, Yuki Ozamoto, Jo Ueda, Akeo Hagiwara
Postoperative air leaks remain a major cause of morbidity after lung resection. This study evaluated the effect of a combination of polyglycolic acid (PGA) sheet and alginate gel on pulmonary air leaks in rats. Four pulmonary sealing materials were evaluated in lung injury: fibrin glue, combination of PGA sheet and fibrin glue, alginate gel, and combination of PGA sheet and alginate gel. With the airway pressure maintained at 20 cmH2 O, a 2 mm deep puncture wound was created on the lung surface using a needle...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29468208/novel-use-of-fibrin-sealant-for-scleral-suture-free-placement-of-a-glaucoma-drainage-device-in-advanced-scleral-thinning
#15
Justin D Harvey, Ronald L Gross, Brian D McMillan
Purpose: This reports a case using fibrin glue to secure a glaucoma drainage device plate to the sclera where there is a concern with the use of suture. Observations: A 13-year-old patient with congenital aniridia and associated glaucoma refractory to topical medications underwent implantation of a glaucoma drainage device (GDD) for improved intraocular pressure (IOP) control. The patient had substantial scleral thinning with staphyloma formation, potentially making the use of traditional suturing techniques problematic...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29462813/hemostatic-efficacy-and-safety-of-the-novel-medical-adhesive-mar-vivo-107-in-a-rabbit-liver-resection-model
#16
Kenji Fukushima, Hirokazu Tanaka, Pramod Kadaba Srinivasan, Kerstin Pawlowsky, Babette Kögel, Shinji Uemoto, Yonson Ku, René H Tolba
BACKGROUND: Topical hemostatic agents are useful when hepatic hemorrhage is difficult to control. The aim of this study was to evaluate the hemostatic efficacy and safety of a biodegradable polyurethane-based adhesive, MAR VIVO-107 (MAR), in comparison with a clinically used fibrin glue. METHODS: Thirty female New Zealand white rabbits were randomly assigned to 3 study groups as follows: MAR (n = 10), fibrin glue (n = 10), and saline groups (n = 10). After standardized partial liver resection was performed, each agent was immediately applied to the wound area...
February 20, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/29462710/fibrin-glue-mesh-fixation-combined-with-mesenchymal-stem-cells-or-exosomes-modulates-the-inflammatory-reaction-in-a-murine-model-of-incisional-hernia
#17
Rebeca Blázquez, Francisco Miguel Sánchez-Margallo, Verónica Álvarez, Alejandra Usón, Federica Marinaro, Javier G Casado
Surgical meshes are effective and frequently used to reinforce soft tissues. Fibrin glue (FG) has been widely used for mesh fixation and is also considered an optimal vehicle for stem cell delivery. The aim of this preclinical study was to evaluate the therapeutic effect of MSCs and their exosomes combined with FG for the treatment of incisional hernia. A murine incisional hernia model was used to implant surgical meshes and different treatments with FG, MSCs and exo-MSCs were applied. The implanted meshes were evaluated at day 7 by anatomopathology, cellular analysis of infiltrating leukocytes and gene expression analysis of TH1/TH2 cytokines, MMPs, TIMPs and collagens...
February 17, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29429786/evaluation-and-management-of-small-dural-tears-in-primary-lumbar-spinal-decompression-and-discectomy-surgery
#18
Marcelo Galarza, Roberto Gazzeri, Raúl Alfaro, Pedro de la Rosa, Cinta Arraez, Claudio Piqueras
Incidental dural tear is one of the most common intraoperative complications in lumbar spine surgery. Yet, its technical management for the prevention of CSF leak is controversial. The technique of managing dural tears depends on the location of the dural tears as well on the length and anatomical characteristics of the dural tear. We propose an anatomical classification for small (less than one cm) dural tears and report on the outcome of managing these dural tears types using different technique for different type...
February 8, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29429648/the-usefulness-of-fibrin-glue-as-a-support-in-the-dissection-of-malignant-cystic-brain-tumors
#19
J Todeschi, Y Pin, F Lersy, F Séverac, I Ollivier, S Kremer, F Proust, H Cebula
BACKGROUND: If the complete microsurgical resection of a brain tumor is a logical oncologic goal, the surgical strategy for the cystic component remains controversial secondary to the risk of morbidity. The objective of this study was to analyze the interest of using fibrin glue in the resection of malignant cystic brain tumors (MCBT). METHODS: Seven patients (median: 60-years-old (range [52-72]/sex ratio M/F: 2.5) were analyzed prospectively in the Neurosurgery Department at Strasbourg University Hospital, from October 2014 to November 2016...
February 8, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29428099/strategies-for-pancreatic-anastomosis-after-pancreaticoduodenectomy-what-really-matters
#20
REVIEW
Jin Xu, Shun-Rong Ji, Bo Zhang, Quan-Xing Ni, Xian-Jun Yu
BACKGROUND: The postoperative pancreatic fistula rate remains approximately 10-20% even in institutions treating a high-volume of pancreatic cases. The best strategy to restore the continuity between the pancreatic remnant and the digestive tract is still in debate. DATA SOURCES: Studies were identified by searching PubMed for studies published between January 1934 (when pancreaticogastrostomy was technically feasible) and December 2016. The following search terms were used: "duct-to-mucosa", "invagination", "pancreaticojejunostomy", "pancreaticogastrostomy," and "pancreaticoduodenectomy"...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
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