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Fibrin glue

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https://www.readbyqxmd.com/read/28068869/a-regenerative-cardiac-patch-formed-by-spray-painting-of-biomaterials-onto-the-heart
#1
Junnan Tang, Adam Vandergriff, Zegen Wang, Michael Hensley, Jhon Cores, Tyler Allen, Phuong-Uyen Dinh, Jinying Zhang, Thomas Caranasos, Ke Cheng
Layering a regenerative polymer scaffold on the surface of the heart, termed as a cardiac patch, has been proven to be effective in preserving cardiac function after myocardial infarction. However, the placement of such a patch on the heart usually needs open-chest surgery, which is traumatic therefore prevents the translation of this strategy into the clinic. We sought to device a novel method to apply a cardiac patch by spray painting in situ polymerizable biomaterials onto the heart with a minimally invasive procedure...
January 9, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28024891/transdural-herniated-lumbar-disc-disease-with-muscle-patch-for-closure-of-durotomy-a-brief-review-of-literature
#2
REVIEW
Harsha A Huliyappa, Rakesh Kumar Singh, Sunil Kumar Singh, Manish Jaiswal, Somil Jaiswal, Chhitij Srivastava, Balkrishna Ojha, Anil Chandra, Satnam Chhabra
PURPOSE: Intradural migration of disc (IDMD) is a rare clinical entity accounting for 0.27-0.33% of all herniated disc diseases. Flimsy or dense adhesion between the ventral dural surface and the opposing posterior longitudinal ligament (PLL) is the principal pathology for intradural migrated disc. The most commonly affected lumbar segments are L4-5 (55%), L3-4 (16%), L5-S1 (10%) and less commonly L2L3 and L1L2. No imaging feature is characteristic and the management protocol of durotomy via an endoscopic method is unclear...
December 15, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28008162/endoscopic-approach-for-major-complications-of-bariatric-surgery
#3
Moon Kyung Joo
As lifestyle and diet patterns have become westernized in East Asia, the prevalence of obesity has rapidly increased. Bariatric surgeries, such as Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and laparoscopic adjustable gastric banding (LAGB), are considered the first-line treatment option in patients with severe obesity. However, postoperative complications have increased and the proper management of these complications, including the use of endoscopic procedures, has become important. The most serious complications, such as leaks and fistulas, can be treated with endoscopic stent placement and injection of fibrin glue, and a novel full-thickness closure over-the-scope clip (OTSC) has been used for treatment of postoperative leaks...
December 23, 2016: Clinical Endoscopy
https://www.readbyqxmd.com/read/27999712/fibrin-glue-injection-into-the-hematoma-cavity-for-refractory-chronic-subdural-hematoma-a-case-report
#4
Saiko Watanabe, Kenichi Amagasaki, Naoyuki Shono, Hiroshi Nakaguchi
BACKGROUND: Repeat burr hole irrigation and drainage has been effective in most cases of recurrent chronic subdural hematoma (CSDH), however, refractory cases require further procedures or other interventions. CASE DESCRIPTION: An 85-year-old male presented with left CSDH, which recurred five times. The hematoma was irrigated and drained through a left frontal burr hole during the first to third surgery and through a left parietal burr hole during the fourth and fifth surgery...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27996378/fast-early-recovery-after-transabdominal-preperitoneal-repair-in-athletes-with-sportsman-s-groin-a-prospective-clinical-cohort-study
#5
Herwig Pokorny, Christoph Resinger, Ines Fischer, Veit Lorenz, Helge Noske, Stefan Podar, Friedrich Längle, Rudolf Schrittwieser
BACKGROUND: Current literature on chronic groin pain suggests that laparoscopic mesh repair on athletes enables a faster recovery and subsequent return to unrestricted athletic activities. The aim of this study was to evaluate the role of transabdominal preperitoneal (TAPP) mesh repair in athletes resistant to conservative therapy. METHODS: A multidisciplinary approach with tailored physiotherapy. Thirty-nine professional athletes with chronic groin pain were referred to surgery at a single clinic...
December 20, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27995192/a-basic-study-of-the-effect-of-the-shielding-method-with-polyglycolic-acid-fabric-and-fibrin-glue-after-endoscopic-submucosal-dissection
#6
Tsujimoto Hiroyuki, Yamanaka Kohki, Miyamoto Hiroe, Horii Tsunehito, Abe Rie, Tanaka Shota, Torii Hiroko, Ozamoto Yuki, Toshitaka Takagi, Takimoto Kengo, Torii Takashi, Konishi Hideyuki, Takamori Hideki, Hagiwara Akeo
Background and study aims: Recently, the shielding method with polyglycolic acid (PGA) fabric and fibrin glue (P-F method) has been reported to prevent serious complications after endoscopic submucosal dissection (ESD). However, the effectiveness and mechanism to prevent complications by this method remain unclear and the corresponding basic research has not been fully conducted. Methods and results: We examined the effectiveness and mechanism of the P-F method, using a surgical ESD model of canine stomach and in vitro experiments...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27995100/the-efficacy-of-fibrin-glue-injection-in-the-prostatic-fossa-on-decreasing-postoperative-bleeding-following-transurethral-resection-of-prostate
#7
Mohammad Hatef Khorrami, Farhad Tadaion, Iman Ghanaat, Farshid Alizadeh
BACKGROUND: To evaluate the efficacy of fibrin glue injection in the prostatic fossa at the end of transurethral resection of prostate (TURP), in decreasing postoperative bleeding in patient with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: In this prospective randomized clinical trial, sixty patients with BPH, who were a candidate for TURP, were randomly divided into two equal groups. In the intervention group, 10cc of fibrin glue was injected in the prostatic fossa at the end of the surgery; through a 5 Fr feeding tube attached to Foley catheter and its tip was proximal to the balloon of catheter...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27988916/experimental-study-of-intraparenchymal-fibrinogen-and-topical-thrombin-to-seal-pleural-defects
#8
Jun Yamamoto, Mitsutomo Kohno, Naoko Izawa, Toshinari Ema, Tai Hato, Ikuo Kamiyama, Takashi Ohtsuka, Masazumi Watanabe
OBJECTIVE: Fibrin sealants are used to close surgical pleural defects, but may detach, causing a postoperative air-leak. We investigated a new means of applying fibrin glue for closing pleural defects. METHODS: Pleural defects (10-mm and 4-mm diameters, respectively) were created in swine and rats via thoracotomy. They were sealed by a) injection of a fibrinogen solution into the lung parenchyma after instillation of a thrombin solution onto the pleural defect (group A), b) fibrinogen and thrombin spray (group B), c) fibrinogen instillation and a thrombin-dipped polyglycolic acid sheet (group C), or d) fibrin glue-coated collagen fleece (group D)...
December 20, 2016: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/27960413/poly-ester-urea-based-adhesives-improved-deployment-and-adhesion-by-incorporation-of-poly-propylene-glycol-segments
#9
Jinjun Zhou, Vrushali Bhagat, Matthew L Becker
The adhesive nature of mussels arises from the catechol moiety in the 3,4-dihydroxyphenylalanine (DOPA) amino acid, one of the many proteins that contribute to the unique adhesion properties of mussels. Inspired by these properties, many biomimetic adhesives have been developed over the past few years in an attempt to replace adhesives such as fibrin, cyanoacrylate, and epoxy glues. In the present work, we synthesized ethanol soluble but water insoluble catechol functionalized poly(ester urea) random copolymers that help facilitate delivery and adhesion in wet environments...
December 14, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27956071/solution-blow-spun-polymer-a-novel-preclinical-surgical-sealant-for-bowel-anastomoses
#10
Nora G Kern, Adam M Behrens, Priya Srinivasan, Christopher T Rossi, John L Daristotle, Peter Kofinas, Anthony D Sandler
BACKGROUND: Solution blow spinning is a technique for depositing polymer fibers with promising potential use as a surgical sealant. This study assessed the feasibility and efficacy of solution blow spun polymer (BSP) for sealing bowel perforations in a mouse model of partial cecal transection. We then evaluated its use for reinforcing a surgical anastomosis in a preclinical piglet model. METHODS: Three commercially available surgical sealants (fibrin glue, polyethylene glycol (PEG) hydrogel, and cyanoacrylate) were compared to BSP in the ability to seal partially transected cecum in mice...
December 5, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27951615/endoscopic-management-of-spinal-intradural-extramedullary-tumors
#11
Vijay Singh Parihar, Nishtha Yadav, Yad Ram Yadav, Shailendra Ratre, Jitin Bajaj, Yatin Kher
Introduction Posterior midline laminectomy is associated with risks of postoperative instability, spinal deformity, extensive bilateral subperiosteal muscle stripping, partial or total facetectomy especially in foraminal tumor extension, increased cerebrospinal fluid leakage, and wound infection. Minimally invasive approaches with the help of a microscope or endoscope using hemilaminectomy have been found to be safe and effective. We report our initial experience of 18 patients using the endoscopic technique...
December 12, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27941383/autologous-blood-versus-fibrin-glue-in-pterygium-excision-with-conjunctival-autograft-surgery
#12
Gaayathri Nadarajah, Vanitha Hema Ratnalingam, Hazlita Mohd Isa
PURPOSE: To evaluate graft stability and recurrence rate between fibrin glue and autologous blood in pterygium conjunctival autograft surgery. METHODS: A prospective, randomized, single-blinded clinical trial to assess the efficacy of autologous blood in place of fibrin glue in pterygium surgery. A total of 120 eyes of 111 patients were randomized according to pterygium morphology, to undergo pterygium surgery with autografting using either autologous blood or fibrin glue...
December 8, 2016: Cornea
https://www.readbyqxmd.com/read/27934783/injectable-pamam-odex-double-crosslinked-hydrogels-with-high-mechanical-strength
#13
Sidi Li, Jianwei Wang, Lifeng Song, Yalin Zhou, Jin Zhao, Xin Hou, Xubo Yuan
In situ injectable double-crosslinked hydrogels containing thiol functionalized poly(amido-amine) dendrimers (Gn-PAMAM-NH2-X) and oxidized dextrans (ODex) were prepared under physiological conditions without using potentially cytotoxic cross-linkers. The double-crosslinked structure was created by Schiff's base reaction and the formation of disulfide bonds. The morphology of the hydrogels was characterized by scanning electron microscopy. The gelation time, swelling and rheological behaviors of the hydrogels were investigated...
December 9, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27931522/effectiveness-of-fibrin-coating-in-the-management-of-web-formation-after-laryngomicrosurgery
#14
REVIEW
K Adachi, T Umezaki
PURPOSE: To explore the effectiveness of fibrin coating in reducing web formation after endoscopic management of the anterior commissure of the larynx. MATERIALS AND METHODS: Using a spray device that is generally used for laparoscopic operations, we covered the wound with fibrin glue (Bolheal®) to avoid web formation. This technique was employed in cases wherein the anterior commissure was mainly managed by laser operation; the glue was sprayed after vaporization...
January 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27923469/may-autologue-fibrin-glue-alone-enhance-ossification-an-unexpected-spinal-fusion
#15
Rosario Maugeri, Giuseppe Roberto Giammalva, Francesca Graziano, Domenico Gerardo Iacopino
No abstract text is available yet for this article.
November 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27911983/fibrin-glue-versus-sutures-for-conjunctival-autografting-in-primary-pterygium-surgery
#16
REVIEW
Vito Romano, Mario Cruciani, Luigi Conti, Luigi Fontana
BACKGROUND: Pterygium, a growth of the conjunctiva over the cornea, is a progressive disease leading in advanced stages to visual impairment, restriction of ocular motility, chronic inflammation and cosmetic concerns. Surgical removal is the treatment of choice, but recurrence can be a problem. Currently the best surgical option in terms of recurrence is conjunctival autograft. To date the most common surgical methods of attaching conjunctival autografts to the sclera are through suturing or fibrin glue...
2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27910727/tannin-based-adhesive-for-protection-of-colonic-anastomosis-in-the-open-abdomen
#17
Youming Deng, Jianan Ren, Guopu Chen, Gefei Wang, Guosheng Gu, Jieshou Li
This study was aimed to evaluate the effect of tannin acid- polyethylene glycol (TP) adhesive on the wound healing process of primary colonic anastomosis in the open abdomen (OA). Adhesion strength test, degradation and hemostatic ability of TP were investigated. In a rat model, after standard colonic anastomoses, rats were divided into three groups: OA group; OA + FG (fibrin glue) group; OA + TP group. Five days after surgery, body weight, anastomotic bursting pressure (ABP), and histology of anastomotic tissue were evaluated...
February 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/27910226/successful-treatment-of-postdural-puncture-headache-using-epidural-fibrin-glue-patch-after-persistent-failure-of-epidural-blood-patches
#18
Kevin Wong, Brian R Monroe
OBJECTIVES: Epidural blood patch is the gold standard for the treatment of postdural puncture headache (PDPH) when conservative treatments have failed to provide any relief. However, alternative therapies are lacking when epidural blood patch persistently fails to improve symptoms. Failure to treat PDPH may lead to significant functional impairment of daily living. Alternative therapies should be sought to accelerate recovery from PDPH. CASE REPORT: This case describes a woman who developed PDPH secondary to accidental dural puncture during a spinal cord stimulator trial...
December 2, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27909197/severity-assessment-in-rabbits-after-partial-hepatectomy-part-ii
#19
N Drude, K Pawlowsky, H Tanaka, K Fukushima, B Kögel, R H Tolba
Although the recognition of pain, distress and discomfort has already been described in 1985 by Morton and Griffiths there is still very little known about the establishment of score sheets especially, regarding post-surgical pain and severity assessment for laboratory animals such as rabbits. In this paper we describe the estimation of severity and recovery status of 36 female New Zealand White rabbits (NZW) in a standardized liver resection model using two different adhesive treatments and one control group...
December 2016: Laboratory Animals
https://www.readbyqxmd.com/read/27900220/use-of-fibrin-glue-as-a-sealant-at-the-anastomotic-line-in-laparoscopic-pyeloplasty-a-randomised-controlled-trial
#20
Ahmed Farouk, Ahmed Tawfick, Mohamed Kotb, Alaa Abdellmaksoud, Ahmed Safaan, Mohamed Yassin, Hassan Shaker
OBJECTIVE: To assess the effectiveness of fibrin glue as a sealant at the anastomotic line of a stentless laparoscopic pyeloplasty (LPP) repair instead of JJ stent insertion. PATIENTS AND METHODS: In all, 46 patients with pelvi-ureteric junction obstruction scheduled for LPP were randomised into two groups each containing 23 patients. Group A underwent stented repair, while group B had a stentless repair together with sealing of the anastomotic line with fibrin glue...
December 2016: Arab Journal of Urology
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