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Fibrin glue

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https://www.readbyqxmd.com/read/29022056/implant-strategy-affects-scaffold-stability-and-integrity-in-cartilage-treatment
#1
M Drobnic, Francesco Perdisa, E Kon, F Cefalì, M Marcacci, G Filardo
PURPOSE: To identify the most appropriate implantation strategy for a novel chondral scaffold in a model simulating the early post-operative phase, in order to optimize the implant procedure and reduce the risk of early failure. METHODS: Eight human cadaveric limbs were strapped to a continuous passive motion device and exposed to extension-flexion cycles (0°-90°). Chondral lesions (1.8 cm diameter) were prepared on condyles, patella and trochlea for the implant of a bi-layer collagen-hydroxyapatite scaffold...
October 11, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29019713/modified-endoscopic-vacuum-therapy-for-nonhealing-esophageal-anastomotic-leak-technique-description-and-review-of-literature
#2
Guy Pines, Ilan Bar, Amir Elami, Shimon Sapojnikov, Ofir Hikri, Dennis Ton, Bruce Mosenkis, Ehud Melzer
BACKGROUND: Endoscopic vacuum-assisted closure (EVAC) therapy is increasingly being used as a new promising method for repairing upper gastrointestinal defects of different etiologies with high success rates. EVAC therapy consists of placing a sponge either within the lumen or within an abscess cavity connected with a nasogastric (NG) tube to a negative pressure system, thus decreasing bacterial contamination and edema and promoting granulation tissue proliferation, thereby gradually decreasing the cavity size until complete closure...
October 11, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28986682/efficacy-and-safety-of-pleurodesis-using-platelet-rich-plasma-and-fibrin-glue-in-management-of-postoperative-chylothorax-after-esophagectomy
#3
Daryoush Hamidi Alamdari, Mehdi Asadi, Ahmad Nejad Rahim, Ghodratollah Maddah, Shahariar Azizi, Soudabeh Shahidsales, Mostafa Mehrabibahar
INTRODUCTION: Chylothorax is by definition a collection of lymphatic fluids in the pleural cavity because of leakage from main thoracic duct or its tributaries. It is an uncommon but serious postoperative complication in esophageal cancer patients. There is no standard therapeutic algorithm for chylothorax because no prospective or randomized trials have yet been performed to evaluate the available treatment options. The aim of this study was to evaluate the efficacy of pleurodesis with a combination of platelet-rich plasma (PRP) and fibrin glue to the treatment of chylothorax after trans-hiatal esophagectomy...
October 6, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28974213/short-term-in-vivo-morphological-changes-of-amniotic-membrane-after-fibrin-glue-assisted-pterygium-surgery-on-anterior-segment-optical-coherence-tomography-a-case-presentation
#4
Jun Hyuk Son, Su-Ho Lim
BACKGROUND: The evaluations of morphological changes of amniotic membrane (AM), even after successful AM transplantation surgery without complications, may be difficult. Moreover, there was no report regarding morphological changes after fibrin glue-assisted AM transplantation with pterygium excision. Here, we highlight and describe the use of spectral domain optical coherence tomography (OCT) for the evaluation of the morphological features of amniotic membrane (AM) and of associated in vivo structural changes after fibrin glue-assisted pterygium surgery...
October 3, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28969169/sutureless-glue-less-conjunctival-autograft-versus-conjunctival-autograft-with-sutures-for-primary-advanced-pterygia-an-interventional-pilot-study
#5
Tanie Natung, Avonuo Keditsu, Wakaru Shullai, Prasanta Kumar Goswami
INTRODUCTION: Conjunctival Autograft (CAG) in pterygium surgery can be attached by sutures or fibrin glue or autologous in situ blood coagulum. Recurrence rate and other parameters related to pterygium surgery between CAG with sutures and autologous in situ blood coagulum have not been compared uniformly in advanced pterygia alone. AIM: To compare and evaluate the outcome of sutureless, glue-less CAG with autologous in situ blood coagulum versus CAG with sutures for primary, advanced pterygium...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28967311/transpetrosal-approach-to-petro-clival-meningioma
#6
Turki Elarjani, Rakshith Shetty, Harminder Singh, Harley B da Silva, Laligam N Sekhar
A 38-year-old woman had a 3-week gradual onset of right-sided weakness in the upper and lower extremities. MRI showed a large left petro-clival meningioma encasing the basilar and left superior cerebellar artery and compressing the brainstem. A posterior transpetrosal approach, with a left temporal and retrosigmoid craniotomy and mastoidectomy, was performed. The tumor was removed in a gross-total resection with questionable remnants adherent to the brainstem. Intraoperative partial iatrogenic injury to the left oculomotor nerve was repaired with fibrin glue...
October 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28966818/intraoperative-monitoring-for-spinal-radiculomedullary-artery-aneurysm-occlusion-treatment-what-when-and-how-long
#7
Federico Landriel, Matteo Baccanelli, Santiago Hem, Eduardo Vecchi, Mariana Bendersky, Claudio Yampolsky
BACKGROUND: Spinal radiculomedullary artery aneurysms are extremely rare. Treatment should be tailored to clinical presentation, distal aneurysm flow, and lesion anatomical features. When a surgical occlusion is planned, it is necessary to evaluate whether intraoperative monitoring (IOM) should be considered as an indispensable tool to prevent potential spinal cord ischemia. METHODS: We present a patient with symptoms and signs of spinal subarachnoid hemorrhage resulting from the rupture of a T4 anterior radiculomedullary aneurysm who underwent open surgical treatment under motor evoked potential (MEP) monitoring...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28965258/low-voltage-coagulation-polyglycolic-acid-sheets-and-fibrin-glue-to-control-air-leaks-in-lung-surgery
#8
Norikazu Kawai, Takeshi Kawaguchi, Shuko Suzuki, Motoaki Yasukawa, Takashi Tojo, Shigeki Taniguchi
OBJECTIVE: We evaluated the efficacy of low-voltage coagulation (LVC) with polyglycolic acid (PGA) sheets (Neoveil, GUNZE Ltd., Japan) and fibrin glue to control intraoperative alveolar air leaks after lung surgery. METHODS: We included 176 patients with non-small cell lung cancer who underwent thoracoscopic lobectomies. When alveolar air leak was confirmed after lung resection, we applied LVC system to the pleural defect followed by layers of PGA sheets and fibrin glue (n = 40)...
September 30, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28958271/operative-outcomes-after-open-abdominal-wall-reconstruction-with-retromuscular-mesh-fixation-using-fibrin-glue-versus-transfascial-sutures
#9
COMPARATIVE STUDY
Adam S Weltz, Udai S Sibia, H Reza Zahiri, Alexa Schoeneborn, Adrian Park, Igor Belyansky
Ideal fixation techniques have not been fully elucidated at the time of complex open abdominal wall reconstruction (AWR). We compared operative outcomes and quality of life with retromuscular mesh fixation using fibrin glue (FG) versus transfascial sutures (TS). Retrospective review identified complex hernia patients who underwent open AWR with mesh from November 2012 through April 2016. Multivariate analysis examined postoperative outcomes between groups. Quality of life was assessed using the Carolinas Comfort Scale...
September 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28954963/application-of-ion-beam-implanted-expanded-polytetrafluoroethylene-to-microvascular-decompression-and-the-surgical-outcome
#10
Koichi Kato, Hiroshi Ujiie, Hiroshi Nakano, Shunsuke Nomura, Masanori Nakagawa, Takashi Higa, Shigeru Kadoyama, Akira Teramoto
Accurate and long-term transposition of offending vessels is required in microvascular decompression (MVD) for the treatment of hemifacial spasm (HFS) and trigeminal neuralgia (TN). We created ion-beam implanted of an expanded-polytetrafluoroethylene (i-ePTFE) surface to transpose offending vessels in MVD. In 13 patients with MVD, we concealed and transposed offending vessels with tape-shaped i-ePTFE, and relieved facial and trigeminal nerve compression by attaching the i-ePTFE to the dura with fibrin glue...
September 26, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28949253/application-of-a-demineralized-cortical-bone-matrix-and-bone-marrow-derived-mesenchymal-stem-cells-in-a-model-of-chronic-rotator-cuff-degeneration
#11
Tanujan Thangarajah, Anita Sanghani-Kerai, Frederick Henshaw, Simon M Lambert, Catherine J Pendegrass, Gordon W Blunn
BACKGROUND: The success of rotator cuff repair is primarily dependent on tendon-bone healing. Failure is common because weak scar tissue replaces the native enthesis, rendering it prone to reruptures. A demineralized bone matrix (DBM) consists of a network of collagen fibers that provide a sustained release of growth factors such as bone morphogenetic proteins. Previous studies have demonstrated that it can regenerate a fibrocartilaginous enthesis. HYPOTHESIS: The use of a DBM and mesenchymal stem cells (MSCs) at the healing enthesis will result in a higher bone mineral density at the tendon insertion and will enhance the regeneration of a morphologically superior enthesis when compared with an acellular human dermal matrix...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28945635/comparison-of-stromal-vascular-fraction-with-or-without-a-novel-bioscaffold-to-fibrin-glue-in-a-porcine-model-of-mechanically-induced-anorectal-fistula
#12
Gerald W Dryden, Eugene Boland, Vijay Yajnik, Stuart Williams
BACKGROUND: Anorectal fistulas (ARFs) are a common, devastating, event in the life of a patient with Crohn's disease. ARFs occur in up to 50% of patients with Crohn's disease. Treatment begins with surgical drainage of the initial abscess, followed by antibiotic therapy, then anti-inflammatory medications. If medical therapy fails to close the fistula tract, surgical intervention is often pursued. Surgery incurs risk of incontinence because of sphincter injury. Increasingly, the role of cell-based therapy is being investigated in ARFs...
September 22, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28943211/rhinophyma-our-experience-based-on-a-series-of-12-cases
#13
P Clarós, M-C Sarr, F-B Nyada, A Clarós
INTRODUCTION: Rhinophyma is a rare, benign and unsightly disease of the skin of the nose that was first described a very long time ago, as illustrated by portrait of an old man with a bulbous nose holding his grandson, by Ghirlandaio in 1490. It was described for the first time by Ferdinando Hebra Von (1816-1880), as the third stage of rosacea. The objective of this study is to report the author's experience and propose a new treatment option in the management of rhinophyma. MATERIAL AND METHODS: We describe our experience of rhinophyma based on a retrospective case study...
September 21, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28942686/fibrin-glue-for-local-haemostasis-in-haemophilia-surgery
#14
E Carlos Rodriguez-Merchan
INTRODUCTION: Local fibrin glue (FG) appears to be a useful local haemostatic agent for severe haemorrhage in people with haemophilia (PWH) undergoing surgical procedures. AIM: To evaluate the role of local FG in PWH. METHODS: A review of the literature on the topic has been performed. RESULTS: Local FG is not always necessary to achieve haemostasis in all surgical procedures performed in PWH. However, it could be a good adjunct therapy, primarily when a surgical field will bleed more than expected (e...
September 23, 2017: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/28938165/a-novel-dopa-albumin-based-tissue-adhesive-for-internal-medical-applications
#15
Wenzhen Zhu, Yvonne Peck, Jabed Iqbal, Dong-An Wang
To date, existing tissue adhesives have various weak points in gluing kinetics and stability - particularly, in biocompatibility, which make most of them remain suboptimal for internal conditions. Herein, a novel mussel-inspired "BCD" tissue glue made of bovine serum albumin (BSA), citrate acid (CA) and dopamine was developed aiming at internal medical applications. BSA was employed as a natural and biocompatible macromolecular backbone; CA was introduced as a dual-functional intermediate to increase reactive carboxyl sites for engraftment of dopamine onto BSA backbone and also block the competing reactive amines from the proteinic backbone...
September 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28932732/sustained-released-mixture-of-vascular-endothelial-growth-factor-165-and-fibrin-glue-strengthens-healing-of-ileal-anastomoses-in-a-rabbit-model-with-intraperitoneal-infection
#16
Zhanwu Li, Wenjun Wang, Xiaozhou Wang, Lei Jiang, Fengyi Wang, Qiang Liu
PURPOSE: To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses. METHODS: One hundred twenty-eight male and female New Zealand white rabbits underwent intraperitoneal infection subsequent ileal anastomosis surgery were divided randomly into 4 groups, including 32 animals in each, applied with saline solution, FG, rhVEGF165 and a mixture of rhVEGF165 with FG (VEGF + FG) on the anastomoses, respectively...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28932349/novel-synthetic-adhesive-as-an-effective-alternative-to-fibrin-based-adhesives
#17
Pramod Kadaba Srinivasan, Vera Sperber, Mamdouh Afify, Hirokazu Tanaka, Kenji Fukushima, Babette Kögel, Felix Gremse, René Tolba
AIM: To compare a novel, fully synthetic, polyurethane based glue (MAR-1) to fibrin sealant in a partial liver resection rat model. METHODS: After 50% resection of the lateral left liver lobe in male Wistar rats (n = 7/group/time point), MAR-1, Fibrin or NaCl was applied. After 14, 21 and 90 postoperative days, sealant degradation, intra-abdominal adhesions were scored, and histological examination of liver tissue was performed. RESULTS: (Mean ± SEM) (MAR-1 vs Fibrin vs NaCl)...
August 28, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28927215/effect-of-fibrin-glue-injection-into-the-cavernous-sinus-for-hemostasis-during-transcavernous-surgery-on-the-cerebral-venous-draining-system
#18
Terushige Toyooka, Naoki Otani, Kojiro Wada, Arata Tomiyama, Hideaki Ueno, Kazuya Fujii, Takuji Yamamoto, Yasuaki Nakao, Kentaro Mori
BACKGROUND: The extradural temporopolar transcavernous approach can be used to treat central skull base pathologies, but control of bleeding from the opened cavernous sinus is essential. Oxidized cellulose cotton packing and fibrin glue injection can be used, but the effect on the postoperative venous draining pattern remains unclear. OBJECTIVE: To investigate changes in the venous drainage pattern immediately after transcavernous surgery with and without fibrin glue injection into the bleeding cavernous sinus...
April 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28906506/stability-of-grafted-implant-placement-sites-after-sinus-floor-elevation-using-a-layering-technique-10-year-clinical-and-radiographic-results
#19
Fouad Khoury, Pierre Keller, Philip L Keeve
PURPOSE: To evaluate long-term survival rates and radiographic stability of sinus floor elevations carried out using a two-layer grafting technique. MATERIALS AND METHODS: Records were analyzed for patients treated with sinus floor elevations using a modified technique. Phycogenic hydroxyapatite (Algipore, Dentsply Sirona Implants) and autogenous bone particles harvested from intraoral sites were grafted in two distinct layers after elevation of the sinus mucosae...
September 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28906385/percutaneous-intratumoral-injection-of-gemcitabine-plus-cisplatin-mixed-with-fibrin-glue-for-advanced-pancreatic-carcinoma-case-report
#20
Biao Yang, Jian-Ping He, Min-Lan Yuan, Wei Li, He Jiao, Xin You, Xing-Rong Liu, Jian Zhao, Chun-Lin Li, Xiao-Bo Fu, Zheng-Yin Liao, Cheng Yi
RATIONALE: The aim of this study was to determine the effectiveness of intratumoral injection of chemotherapeutics in improving the quality of life and survival of patients with pancreatic carcinoma. PATIENT CONCERNS: We present a case series of 5 patients with unresectable pancreatic adenocarcinoma. DIAGNOSES: Patients diagnosed with unresectable poorly differentiated pancreatic ductal adenocarcinoma by intraoperative frozen biopsyor percutaneous biopsy...
September 2017: Medicine (Baltimore)
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