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Structural heart intervention

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https://www.readbyqxmd.com/read/28629929/interactions-between-micrornas-and-long-non-coding-rnas-in-cardiac-development-and-repair
#1
REVIEW
Alessio Rotini, Ester Martínez-Sarrà, Enrico Pozzo, Maurilio Sampaolesi
Non-coding RNAs (ncRNAs) are emerging players in muscle regulation. Based on their length and differences in molecular structure, ncRNAs are subdivided into several categories including small interfering RNAs, stable non-coding RNAs, microRNAs (miRs), long non-coding RNAs (lncRNAs), and circular RNAs. miRs and lncRNAs are able to post-transcriptionally regulate many genes and bring into play several traits simultaneously due to a myriad of different targets. Recent studies have emphasized their importance in cardiac regeneration and repair...
June 16, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28624249/the-role-of-3-d-heart-models-in-planning-and-executing-interventional-procedures
#2
REVIEW
Elena K Grant, Laura J Olivieri
Percutaneous interventions aimed at addressing congenital and structural heart disease are simultaneously becoming more common and more complex as time progresses. An increasing number of heart defects that had previously required open heart surgery can now be successfully addressed in the cardiac catheterization laboratory. Adequate preprocedural preparation for these novel, complex procedures is critical to ensure their success. Diagnostic data can be collected before the intervention and displayed in multiple formats during the procedure...
February 24, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28617184/patient-perceptions-of-experience-with-cardiac-rehabilitation-after-isolated-heart-valve-surgery
#3
Tina B Hansen, Selina K Berg, Kirstine L Sibilitz, Ann D Zwisler, Tone M Norekvål, Anne Lee, Niels Buus
BACKGROUND: Little evidence exists on whether cardiac rehabilitation is effective for patients after heart valve surgery. Yet, accepted recommendations for patients with ischaemic heart disease continue to support it. To date, no studies have determined what heart valve surgery patients prefer in a cardiac rehabilitation programme, and none have analysed their experiences with it. AIMS: The purpose of this qualitative analysis was to gain insight into patients' experiences in cardiac rehabilitation, the CopenHeartVR trial...
June 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28602371/interventional-therapies-for-heart-failure-in-older-adults
#4
REVIEW
Dhaval Kolte, Jinnette Dawn Abbott, Herbert D Aronow
Heart failure (HF) remains the leading cause of hospitalization in older adults and is associated with increased morbidity and mortality despite the use of guideline-directed medical therapy. There has been tremendous progress in the development of novel transcatheter and interventional therapies for HF over the past decade. The evolution of structural heart disease interventions and interventional HF has led to a multidisciplinary heart team approach in the management of HF patients. Careful selection of the appropriate patient population and end points in future randomized controlled trials will be crucial to demonstrate the potential efficacy of the novel interventional HF therapies...
July 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/28601691/effects-of-a-nurse-led-transitional-care-program-on-clinical-outcomes-health-related-knowledge-physical-and-mental-health-status-among-chinese-patients-with-coronary-artery-disease-a-randomized-controlled-trial
#5
Pan Zhang, Yu-Ding Hu, Feng-Mei Xing, Chang-Zai Li, Wang-Feng Lan, Xiao-Li Zhang
BACKGROUND: Coronary artery disease is a major cause of morbidity and mortality among adults worldwide, including China. After a hospital stay, transitional care could help to ensure improved patient care and outcomes, and reduce Medicare costs. Nevertheless, the results of the existing transitional care are not always satisfactory and our knowledge of how to perform effective transitional care for patients with coronary artery disease is limited in mainland China. OBJECTIVES: To examine the effectiveness of a nurse-led transitional care program on clinical outcomes, health-related knowledge, and physical and mental health status among Chinese patients with coronary artery disease...
April 14, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28601385/echocardiographic-fluoroscopic-fusion-imaging-in-transseptal-puncture-a-new-technology-for-an-old-procedure
#6
Francesco F Faletra, Luigi Biasco, Giovanni Pedrazzini, Marco Moccetti, Elena Pasotti, Laura Anna Leo, Giorgio Cautilli, Tiziano Moccetti, Mark J Monaghan
In an era of catheter-based structural heart disease and left-side electrophysiologic interventions, transseptal puncture (TSP) is probably the most common transcatheter procedure. Experienced interventional cardiologists and electrophysiologists may safely perform TSP using fluoroscopic guidance alone. However, at present TSP is usually the first step in complex percutaneous catheter-based structural heart disease procedures and necessitate a precise site-specific TSP. Thus, in these procedures most interventional cardiologists perform TSP under fluoroscopic and two- or three-dimensional transesophageal echocardiographic guidance...
June 7, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28595844/subclinical-myocardial-impairment-in-metabolic%C3%A2-diseases
#7
REVIEW
Wojciech Kosmala, Prash Sanders, Thomas H Marwick
Type 2 diabetes mellitus (T2DM) and obesity are important contributors to nonischemic heart failure (HF) and atrial fibrillation. There is a 2- to 5-fold increase in HF associated with T2DM, and there is a 5% in HF risk in men and 7% increment in women for every unit increment in body mass index, after adjustment for traditional cardiovascular risk factors. Likewise, the risk of atrial fibrillation increases by about 6% per unit increase in body mass index. Metabolic cardiomyopathy leads to a number of changes in cardiac structure and function that can be recognized by imaging in the asymptomatic phase, and these parameters can be used for monitoring the progression of disease or the response to therapy...
June 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28586420/appropriateness-criteria-for-the-use-of-cardiovascular-imaging-in-heart-valve-disease-in-adults-a-european-association-of-cardiovascular-imaging-report-of-literature-review-and-current-practice
#8
John B Chambers, Madalina Garbi, Koen Nieman, Saul Myerson, Luc A Pierard, Gilbert Habib, Jose Luis Zamorano, Thor Edvardsen, Patrizio Lancellotti, Dr Victoria Delgado, Prof Bernard Cosyns, Prof Erwan Donal, Dr Raluca Dulgheru, Dr Maurizio Galderisi, Dr Massimo Lombardi, Dr Denisa Muraru, Dr Philipp Kauffmann, Prof Nuno Cardim, Assoc Prof Kristina Haugaa, Dr Raphael Rosenhek
Heart valve disease is common and a major indication for imaging. Echocardiography is the first-line imaging technique for diagnosis, assessment, and serial surveillance. However, other modalities, notably cardiac magnetic resonance imaging and computerized tomography, are used if echocardiographic imaging is suboptimal or to obtain complementary information, particularly to aid risk assessment in individual patients. This review is a summary of current evidence for state-of-the-art clinical practice to inform appropriateness criteria for heart valve disease...
May 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28583211/parenting-a-child-at-home-with-hypoplastic-left-heart-syndrome-experiences-of-commitment-of-stress-and-of-love
#9
Annie M Cantwell-Bartl, James Tibballs
OBJECTIVE: To evaluate the experiences of parenting a child with hypoplastic left heart syndrome after the child has been discharged home from hospital. DESIGN: A study of the parents' experiences using face-to-face interviews and psychometric measures with parents whose child had survived stage surgery. SETTING: Parents were interviewed within the home environment or within the hospital if that was their choice. SUBJECTS: A total of 29 parents (16 mothers and 13 fathers) of surviving children...
June 6, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28561210/cardiac-etiologies-of-hydrops-fetalis
#10
Shi-Min Yuan
Cardiac etiologies of hydrops fetalis have been a topic of concern due to challenging perinatal management. The common cardiac etiologies leading to hydrops fetalis include structural cardiac anomalies, cardiac dysrhythmias, cardiac tumors, cardiomyopathy and myocarditis. The mechanisms of cardiogenic hydrops fetalis may be: 1) elevation of atrial pressure and volume overload, 2) decrease of cardiac output, and 3) development of congestive heart failure. The diagnosis of hydrops fetalis was usually made at 19-36 gestational weeks, when ultrasound is a highly effective diagnostic method...
April 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28558095/economic-evaluation-of-quality-improvement-interventions-designed-to-prevent-hospital-readmission-a-systematic-review-and-meta-analysis
#11
Teryl K Nuckols, Emmett Keeler, Sally Morton, Laura Anderson, Brian J Doyle, Joshua Pevnick, Marika Booth, Roberta Shanman, Aziza Arifkhanova, Paul Shekelle
Importance: Quality improvement (QI) interventions can reduce hospital readmission, but little is known about their economic value. Objective: To systematically review economic evaluations of QI interventions designed to reduce readmissions. Data Sources: Databases searched included PubMed, Econlit, the Centre for Reviews & Dissemination Economic Evaluations, New York Academy of Medicine's Grey Literature Report, and Worldcat (January 2004 to July 2016)...
May 30, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28554497/evaluating-the-older-adult-experience-of-a-web-based-tablet-delivered-heart-failure-self-care-program-using-gerontechnology-principles
#12
Harleah Buck, Anthony Pinter, Erika Poole, John Boehmer, Andrew Foy, Sara Black, Tom Lloyd
The goals of gerontechnology are to develop technology that facilitates goal attainment and improves satisfaction with life for older adults. Few mHealth technology systems have been evaluated using these criteria. The purpose of this paper was to present the qualitative analysis of participant post-intervention interviews from the tablet-delivered Penn State Heart Assistant intervention. Semi-structured interviews (n = 12) were conducted after the completion of a 30 day study protocol. Interviews were transcribed verbatim by a professional transcriptionist, then analyzed using an iterative process of coding, categorization, and thematic development using DeDoose software and a gerontechnology interpretive lens...
May 26, 2017: Geriatric Nursing
https://www.readbyqxmd.com/read/28551818/novel-three-dimensional-image-fusion-software-to-facilitate-guidance-of-complex-cardiac-catheterization-3d-image-fusion-for-interventions-in-chd
#13
Sebastian Goreczny, Pawel Dryzek, Gareth J Morgan, Maciej Lukaszewski, Jadwiga A Moll, Tomasz Moszura
We report initial experience with novel three-dimensional (3D) image fusion software for guidance of transcatheter interventions in congenital heart disease. Developments in fusion imaging have facilitated the integration of 3D roadmaps from computed tomography or magnetic resonance imaging datasets. The latest software allows live fusion of two-dimensional (2D) fluoroscopy with pre-registered 3D roadmaps. We reviewed all cardiac catheterizations guided with this software (Philips VesselNavigator). Pre-catheterization imaging and catheterization data were collected focusing on fusion of 3D roadmap, intervention guidance, contrast and radiation exposure...
May 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28550403/healthcare-utilization-and-costs-in-ards-survivors-a-1-year-longitudinal-national-us-multicenter-study
#14
A Parker Ruhl, Minxuan Huang, Elizabeth Colantuoni, Taruja Karmarkar, Victor D Dinglas, Ramona O Hopkins, Dale M Needham
PURPOSE: To evaluate (1) post-discharge healthcare utilization and estimated costs in ARDS survivors, and (2) the association between patient and intensive care-related variables, and 6-month patient status, with subsequent hospitalization and costs. METHODS: Longitudinal cohort study enrolling from four ARDSNet trials in 44 US hospitals. Healthcare utilization was collected via structured interviews at 6 and 12 months post-ARDS, and hospital costs estimated via the Medical Expenditure Panel Survey...
May 26, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28545533/food-beliefs-and-practices-among-the-kalenjin-pregnant-women-in-rural-uasin-gishu-county-kenya
#15
Roselyter Monchari Riang'a, Jacqueline Broerse, Anne Kisaka Nangulu
BACKGROUND: Understanding food beliefs and practices is critical to the development of dietary recommendations, nutritional programmes, and educational messages. This study aimed to understand the pregnancy food beliefs and practices and the underlying reasons for these among the contemporary rural Kalenjin communities of Uasin Gishu County, Kenya. METHODS: Through semi-structured interviews, data was collected from 154 pregnant and post-natal Kalenjin women about restricted and recommended foods, and why they are restricted or recommended during pregnancy...
May 25, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28542428/age-dependent-electrical-and-morphological-remodeling-of-the-drosophila-heart-caused-by-herg-seizure-mutations
#16
Karen Ocorr, Alexander Zambon, Yoav Nudell, Santiago Pineda, Soda Diop, Min Tang, Takeshi Akasaka, Erika Taylor
Understanding the cellular-molecular substrates of heart disease is key to the development of cardiac specific therapies and to the prevention of off-target effects by non-cardiac targeted drugs. One of the primary targets for therapeutic intervention has been the human ether a go-go (hERG) K+ channel that, together with the KCNQ channel, controls the rate and efficiency of repolarization in human myocardial cells. Neither of these channels plays a major role in adult mouse heart function; however, we show here that the hERG homolog seizure (sei), along with KCNQ, both contribute significantly to adult heart function as they do in humans...
May 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28540402/a-qualitative-evaluation-of-breast-cancer-survivors-acceptance-of-and-preferences-for-consumer-wearable-technology-activity-trackers
#17
Nga H Nguyen, Nyssa T Hadgraft, Melissa M Moore, Dori E Rosenberg, Chris Lynch, Marina M Reeves, Brigid M Lynch
BACKGROUND: Physical inactivity and sedentary behaviour are common amongst breast cancer survivors. These behaviours are associated with an increased risk of comorbidities such as heart disease, diabetes and other cancers. Commercially available, wearable activity trackers (WATs) have potential utility as behavioural interventions to increase physical activity and reduce sedentary behaviour within this population. PURPOSE: The purpose of the study is to explore the acceptability and usability of consumer WAT amongst postmenopausal breast cancer survivors...
May 24, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28540070/an-update-on-intraoperative-three-dimensional-transesophageal-echocardiography
#18
REVIEW
Lisa Qia Rong
Transesophageal echocardiography (TEE) was first used routinely in the operating rooms in the 1980s to facilitate surgical decision-making. Since then, TEE has evolved from the standard two-dimensional (2D) exam to include focused real-time three-dimensional (RT-3D) imaging both inside and outside the operating rooms. Improved spatial and temporal resolution due to technological advances has expedited surgical interventions in diseased valves. 3D imaging has also emerged as a crucial adjunct in percutaneous interventions for structural heart disease...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28537000/advances-in-clinical-cardiology-2016-a-summary-of-the-key-clinical-trials
#19
REVIEW
Alastair Gray, Conor McQuillan, Ian B A Menown
INTRODUCTION: The findings of many new cardiology clinical trials over the last year have been published or presented at major international meetings. This paper aims to describe and place in context a summary of the key clinical trials in cardiology presented between January and December 2016. METHODS: The authors reviewed clinical trials presented at major cardiology conferences during 2016 including the American College of Cardiology (ACC), European Association for Percutaneous Cardiovascular Interventions (EuroPCR), European Society of Cardiology (ESC), European Association for the Study of Diabetes (EASD), Transcatheter Cardiovascular Therapeutics (TCT), and the American Heart Association (AHA)...
May 23, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28528161/functional-implication-of-mitral-annular-disjunction-in-mitral-valve-prolapse-a-quantitative-dynamic-3d-echocardiographic%C3%A2-study
#20
Alex Pui-Wai Lee, Chun-Na Jin, Yiting Fan, Randolph H L Wong, Malcolm J Underwood, Song Wan
OBJECTIVES: This study aimed to assess the hypothesis that mitral annular disjunction (MAD) is associated with abnormal annular dynamics due to decoupling of annular-ventricular function. BACKGROUND: MAD, defined as a separation between the atrial wall-mitral valve (MV) junction and left ventricular (LV) attachment, is a structural abnormality occurring in MV prolapse (MVP). Few data exist on the 3-dimensional (3D) geometry of MAD and its functional implication...
May 11, 2017: JACC. Cardiovascular Imaging
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