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Ngozi Achi, Christopher Ohaeri, Ifeoma Ijeh, Chinedum Eleazu, Kalu Igwe, Chima Onyeabo
There is paucity of information in literature on the effect of Cnidoscolus aconitifolius on the hematological, coagulation activities, electrolyte balance and antioxidant activities of humans or animals. </p><p> Objectives: To determine the ameliorative potentials of methanol fractions of Cnidoscolus aconitifolius on hematological, coagulation, electrolyte, hepatic and renal antioxidant activities of streptozotocin- induced diabetic rats using standard techniques. </p><p> Method: Thirty rats, distributed into five groups of six rats each were used for this study...
March 27, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
(no author information available yet)
[This corrects the article DOI: 10.1371/journal.pone.0183935.].
2017: PloS One
S M Lira, N V Canabrava, S R Benjamin, J Y G Silva, D A Viana, C L S Lima, P F M Paredes, M M M Marques, E O Pereira, E A M Queiroz, M I F Guedes
Diabetes mellitus is one of the most common chronic degenerative diseases, and it is estimated to increase worldwide to around 415 million and to impact 642 million in 2040. Research shows that some plants are sources of bioactive compounds against diabetes. Thus, the objective of this work was to evaluate the oral toxicity and the hypoglycemic effect of the aqueous extract of the leaves of Cnidoscolus quercifolius Pohl. Diabetes was induced in Swiss mice with streptozotocin and the mice were treated with an aqueous extract of C...
August 31, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Penha Patrícia Cabral Ribeiro, Denise Maria de Lima E Silva, Cristiane Fernandes de Assis, Roberta Targino Pinto Correia, Karla Suzanne Florentino da Silva Chaves Damasceno
To the best of our knowledge, this is the first report in the literature concerning the bioactive properties of faveleira products. This work focuses on the physicochemical evaluation of faveleira oil, as well as it investigates the bioactive properties of faveleira seeds, faveleira oil and the press cake obtained during the oilseed processing. The seeds were cold pressed and the following tests were performed: physicochemical characteristics (acidity, peroxide values, moisture and volatile matter, density and viscosity) and fatty acid profile of faveleira oil; total phenolic and flavonoid content of faveleira seed and press cake; antibacterial activity of seed, oil and press cake; and antioxidant activity (DPPH radical scavenging activity, reducing power assay, total antioxidant capacity, superoxide radical scavenging assay and oxygen radical absorbance capacity) of seed, oil and press cake...
2017: PloS One
Erika P Alves, Rennaly de F Lima, Carolina M de Almeida, Irlan A Freires, Pedro L Rosalen, Ana Ltg Ruiz, Ana F Granville-Garcia, Gustavo P Godoy, Jozinete V Pereira, Edja Mm de Brito Costa
BACKGROUND: Bauhinia forficata and Cnidoscolus quercifolius plants are commonly used in folk medicine. However, few studies have investigated their therapeutic potential. AIM: Herein, we evaluated the antimicrobial activity of B. forficata and C. quercifolius extracts against microorganisms of clinical relevance and their antiproliferative potential against tumor cells. MATERIALS AND METHODS: The following tests were performed: Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC)/minimum fungicidal concentration (MFC), inhibition of biofilm adhesion, and effects on cell morphology...
August 1, 2017: Journal of Contemporary Dental Practice
Juan Fernando Pío-León, Francisco Delgado-Vargas, Bernardo Murillo-Amador, José Luís León-de-la-Luz, Rito Vega-Aviña, Alejandra Nieto-Garibay, Miguel Córdoba-Matson, Alfredo Ortega-Rubio
Ethnobotany is an adequate tool to identify the most import wild edible plants used by local people and to develop strategies for its sustainable use and policy making. This research records the wild edible plants used by the inhabitants of the Sierra la Laguna Biosphere Reserve, in Mexico, and identified priority species for sustainable development. The employed quantitative approach included the application of a food-oriented index named Food Significance Index (FSI), which integrated cultural, agricultural and food parameters; moreover, it used multivariate analysis to identify priority edible species for use and/or conservation...
October 1, 2017: Journal of Environmental Management
Mathias B Forrester
OBJECTIVE: Texas bull nettle (Cnidoscolus texanus) is covered in bristly hairs similar to stinging nettle. Contact with the plant may result in intense dermal pain, burning, itching, cellulitis, and allergic reaction. This study characterizes C texanus exposures reported to a large state-wide poison center system. METHODS: Cases were C texanus exposures reported to Texas poison centers during 2000-2015. The distribution of cases was determined for patient demographics, exposure circumstances, and patient outcome...
April 3, 2017: Wilderness & Environmental Medicine
Mariana Z Pérez-González, Gabriel A Gutiérrez-Rebolledo, Lilián Yépez-Mulia, Irma S Rojas-Tomé, Julieta Luna-Herrera, María A Jiménez-Arellanes
Cnidoscolus chayamansa is a medicinal and edible plant known as Chaya, is commonly used as an anti-inflammatory, antiprotozoal, antibacterial agent and as a remedy for respiratory illness, gastrointestinal disorders, and vaginal infections related with the inflammation process. In this paper, we describe the plant's phytochemical analysis and biological activities (antimycobacterial, antibacterial, antiprotozoal, and anti-inflammatory properties) of the CHCl3:MeOH (1:1) leaves extract and isolated compounds, as well as the acute and sub-acute toxic effects...
May 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
N K Achi, O C Ohaeri, I I Ijeh, C Eleazu
BACKGROUND: No study to date has investigated the effect of different polar solvent extracts from Cnidoscolus aconitifolius leaves on glycemic control as used in folk medicine. Hence this study which investigated the effect of ethanol extract and fractions of C. aconitifolius leaves on body weights, relative organ weights, serum levels of glucose, lipid profiles and insulin in streptozotocin induced diabetic rats and on oral glucose tolerance of normoglycemic rats. METHODS: The ethanol extract was partitioned using methanol, hexane and chloroform to obtain different fractions...
February 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Paulo Fernando Machado Paredes, Fábio Roger Vasconcelos, Raquel Teixeira Terceiro Paim, Márcia Maria Mendes Marques, Selene Maia De Morais, Sandra Machado Lira, Isabel Desidério Braquehais, Ícaro Gusmão Pinto Vieira, Francisca Noelia Pereira Mendes, Maria Izabel Florindo Guedes
The caatinga, an exclusively Brazilian biome, is one of the most endangered vegetation systems in the planet. To be exploited rationally, its potential needs to be scientifically demonstrated. Among these is the faveleira, used in northeastern Brazil. It stands out for its extraordinary drought resistance and medicinal properties. The objective of this study was to assess the therapeutic potential of compounds extracted from Cnidoscolus quercifolius Pohl in preventing disease and its rational use as a herbal therapeutic tool...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
Aline M Melo, Sarah J C Silva, Roberto Ramos-Sobrinho, Mayra M M Ferro, Iraildes P Assunção, Gaus S A Lima
Begomoviruses have been detected infecting the weed Cnidoscolus urens (family Euphorbiaceae) since 2004, but the viral species to which these viruses belonged was not known. Here, we report for the first time the complete genome sequence of a bipartite begomovirus obtained from C. urens collected in the state of Alagoas, Brazil. This isolate met the criteria to be classified as a member of a new begomovirus species, and the tentative name cnidoscolus mosaic leaf deformation virus (CnMLDV) is proposed. Pairwise sequence comparisons and phylogenetic analysis showed that the DNA-A genomic component of CnMLDV is most closely related to that of passionfruit severe leaf distortion virus, with 86...
September 2016: Archives of Virology
G Arceo-Gómez, C Alonso, L Abdala-Roberts, V Parra-Tabla
Pollen deposition and pollen tube formation are key components of angiosperm reproduction but intraspecific variation in these has rarely been quantified. Documenting and partitioning (populations, plants and flowers) natural variation in these two aspects of plant reproduction can help uncover spatial mosaics of reproductive success and underlying causes. In this study, we assess variation in pollen deposition and pollen tube formation for the endemic monoecious shrub Cnidoscolus souzae throughout its distribution range in Mexico, and determine how this variation is structured among populations, plants and flowers...
July 2016: Plant Biology
Dulce M Jiménez-Aguilar, Michael A Grusak
The green leafy vegetables Cnidoscolus aconitifolius and Crotalaria longirostrata are native to Mexico and Central America, while Solanum scabrum and Gynandropsis gynandra are native to Africa. They are consumed in both rural and urban areas in those places as a main food, food ingredient or traditional medicine. Currently, there is limited information about their nutritional and phytochemical composition. Therefore, mineral, vitamin C, phenolic and flavonoid concentration, and antioxidant activity were evaluated in multiple accessions of these leafy vegetables, and their mineral and vitamin C contribution per serving was calculated...
December 2015: Plant Foods for Human Nutrition
S Numa, L Rodríguez, D Rodríguez, E Coy-Barrera
One of the main pests of commercial rose crops in Colombia is the phytophagous mite Tetranychus urticae Koch. To manage this pest, synthetic chemicals have traditionally been used, some of which are well known to be potentially toxic to the environment and humans. Therefore, alternative strategies for pest management in greenhouse crops have been developed in recent years, including biological control with natural enemies such as parasitoids, predators and entomopathogenic microorganisms as well as chemical control using plant extracts...
2015: SpringerPlus
Hiatzy E Zapata-Estrella, Azeret D M Sánchez-Pardenilla, Karlina García-Sosa, Fabiola Escalante-Erosa, Fátima de Campos-Buzzi, Nara Lins Meira-Quintão, Valdir Cechinel-Filho, Luis M Peña-Rodríguez
The bioassay-guided purification of the ethanol extracts of Acmella pilosa and Cnidoscolus souzae, two plants of the native flora of the Yucatan Peninsula used in traditional medicine to treat inflammation and pain, resulted in the identification of rosmarinic acid (1) and caffeic acid (2) as the bioactive metabolites from A. pilosa, and of 7-deoxynimbidiol (4) as the major bioactive metabolite from C. souzae. Metabolites 1, 2, and 4 proved to be responsible for the antioxidant activity originally detected in the corresponding organic crude extracts; 7-deoxynimbidiol (4) showed good analgesic and anti-inflammatory activities, inhibiting the pain induced by PGE2 and reducing the edema induced by carrageenan, respectively...
September 2014: Natural Product Communications
Leandra Macedo de Araújo Gomes, Thayne Mayra de Andrade, Juliane Cabral Silva, Julianeli Tolentino de Lima, Lucindo José Quintans-Junior, Jackson Roberto Guedes da Silva Almeida
BACKGROUND: Cnidoscolus quercifolius is a species popularly known as favela and faveleira, and belonging to the Caatinga biome (semi-arid vegetation, Brazil), where is used in folk medicine as an anti-inflammatory. OBJECTIVE: The aim was to evaluate the anti-inflammatory effect of the ethanolic extract from barks (Cqb-EtOH) and leaves (Cql-EtOH) of C. quercifolius in mice using experimental models of inflammation. MATERIALS AND METHODS: The preliminary phytochemical analysis of the ethanolic extract was performed...
October 2014: Pharmacognosy Research
Yamara A S de Menezes, Juliana Félix-Silva, Arnóbio A da Silva-Júnior, Ivanise M M Rebecchi, Adeliana S de Oliveira, Adriana F Uchoa, Matheus de F Fernandes-Pedrosa
Proteolytic enzymes are important macromolecules in the regulation of biochemical processes in living organisms. Additionally, these versatile biomolecules have numerous applications in the industrial segment. In this study we have characterized a protein-rich fraction of Cnidoscolus urens (L.) Arthur leaves, rich in proteolytic enzymes, and evaluated its effects on the coagulation cascade. Three protein-rich fractions were obtained from the crude extract of C. urens leaves by precipitation with acetone. Fraction F1...
2014: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Rosa Virginia García-Rodríguez, Gabriel Alfonso Gutiérrez-Rebolledo, Enrique Méndez-Bolaina, Alberto Sánchez-Medina, Octavio Maldonado-Saavedra, Miguel Ángel Domínguez-Ortiz, Maribel Vázquez-Hernández, Omar David Muñoz-Muñiz, Jesús Samuel Cruz-Sánchez
ETHNOPHARMACOLOGICAL RELEVANCE: Cnidoscolus chayamansa Mc Vaugh (Euphorbiaceae) is commonly known as 'chaya' in Central America. In South East Mexico, because of its high nutritional values, is an important part of the diet of many indigenous communities. Chaya is also used as a traditional remedy for the treatment of diabetes, rheumatism, gastrointestinal disorders and inflammation-related diseases. Although Cnidoscolus chayamansa is one of most used and valued medicinal plants, only few studies on documenting its pharmacological properties can be found...
February 3, 2014: Journal of Ethnopharmacology
Ademola A Oyagbemi, Adebimpe A Odetola
INTRODUCTION: This study was designed to evaluate the ameliorative and hypocholesterolemic effects of dietary supplementation of Cnidoscolus aconitifolius leaf meal (CALM) on hepatic injury and kidney injury associated with protein energy malnutrition (PEM). MATERIALS AND METHODS: In this study, PEM was induced in weaning male Wistar albino rats by feeding them with low protein diet for 2 weeks. The effects of several recovery diets containing 20% soya protein or 20% C...
October 2013: Pharmacognosy Research
M S Coelho, M S Belmiro, J C Santos, G W Fernandes
Our goal was to identify herbivory patterns from two insect guilds associated with Cnidoscolus quercifolius in a tropical deciduous forest in northeastern Brazil. We sampled four different habitats: (1) forest edge, (2) mesic (near to the perennial water source), (3) forest interior and (4) rupestrian fields. Habitat edge had lower leaf damage than rupestrian, mesic and forest interior habitats. Nevertheless, abundance of galls at the edge habitat was higher than at mesic, forest interior and/or rupestrian habitats...
August 2012: Brazilian Journal of Biology, Revista Brasleira de Biologia
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