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https://www.readbyqxmd.com/read/27888956/improving-adherence-in-hospitalized-patients-diagnosed-with-schizophrenia-an-integrative-one-on-one-intervention
#1
Sagit Dahan, Pnina Behrbalk, Tali Stolovy, Chaya Greenberger
OBJECTIVE: This study examined an individualized integrative nursing intervention for improving attitude and adherence. METHODS: The sample included 60 patients, randomly assigned to an experimental or control group. Measures included The Visual Analog Scale for Assessing Treatment Compliance and the Drug Attitude Inventory (DAI- 10). RESULTS: Significant differences were found in attitude and reported adherence for the experimental group, before and after...
December 2016: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/27843923/spongiotic-trachyonychia-treated-with-topical-corticosteroids-using-the-paper-tape-occlusion-method
#2
EDITORIAL
Tomo Sakiyama, Ayaka Chaya, Tomoko Shimizu, Tamotsu Ebihara, Masataka Saito
No abstract text is available yet for this article.
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27833274/effect-of-external-volume-expansion-on-the-survival-of-fat-grafts
#3
Raghuveer Reddy, Subramania Iyer, Mohit Sharma, Sundeep Vijayaraghavan, P Kishore, Jimmy Mathew, A K K Unni, P Reshmi, Rakesh Sharma, Chaya Prasad
INTRODUCTION: External volume expansion (EVE) is one method, which has been utilised for increasing the survival of adipose tissue grafts. EVE releases positive pressure from the graft and also induces intense levels of edema that decreases diffusion of metabolites essential for graft survival initially. The ideal timing of external volume expansion in relation to the injection of the fat to facilitate survival is not yet clear. AIMS AND OBJECTIVES: This study was undertaken to evaluate and compare the efficacy of external volume expansion applied at variable time points in relation to the injection of the fat...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/27824702/fistula-associated-anorectal-cancer-in-the-setting-of-crohn-s-disease
#4
Chaya Shwaartz, Jordan A Munger, Juan R Deliz, Joseph E Bornstein, Stephan R Gorfine, David B Chessin, Daniel A Popowich, Joel J Bauer
BACKGROUND: Cancer arising from perianal fistulas in patients with Crohn's disease is rare. There are only a small series of articles that describe sporadic cases of perianal cancer in Crohn's disease fistulas. Therefore, there are no clear guidelines on how to appropriately screen patients at risk and choose proper management. OBJECTIVE: The purpose of this study was to describe patients diagnosed with cancer in perianal fistulas in the setting of Crohn's disease...
December 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27816578/distinctive-gene-expression-profile-in-women-with-history-of-postpartum-depression
#5
Anna Landsman, Rafael Aidelman, Yoav Smith, Matthew Boyko, Chaya Greenberger
Postpartum depression (PPD) is a disease which incorporates a variety of depressive states differing in nature and severity. To assist in the understanding of the pathogenesis of the disease, we aimed to ascertain a molecular mechanism underlying PPD development. We applied microarray technology to characterize gene expression of euthymic women with a history of PPD and compared the results with healthy controls. Our study demonstrated that women who considered euthymic on a clinical level, in fact, had an altered molecular profile when compared to participants with no PPD history...
November 2, 2016: Genomics
https://www.readbyqxmd.com/read/27776585/incidence-of-tuberculosis-meningitis-in-a-high-hiv-prevalence-setting-time-series-analysis-from-2006-to-2011
#6
S Chaya, Z Dangor, F Solomon, S A Nzenze, A Izu, S A Madhi
SETTING: This study was undertaken at a tertiary hospital in Soweto, a peri-urban low-middle income setting. Mycobacterium tuberculosis meningitis (TBM) is a severe manifestation of extra-pulmonary tuberculosis. OBJECTIVE: To describe the incidence, mortality and clinical features of TBM in human immunodeficiency virus (HIV) infected and non-infected children in South Africa from 2006 to 2011. DESIGN: A retrospective, cross-sectional descriptive study...
November 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27768620/computed-tomographic-appearance-of-organizing-pneumonia-in-an-oncologic-patient-population
#7
Niamh M Long, Andrew J Plodkowski, Rachel Schor-Bardach, Alexander I Geyer, Junting Zheng, Chaya S Moskowitz, Michelle S Ginsberg
OBJECTIVE: The aims of this study were to describe the computed tomographic features of organizing pneumonia (OP) in an oncologic patient population and to also identify features associated with lung cancer and patients undergoing hematopoietic stem cell transplant (HSCT). METHODS: In retrospective computed tomographies from 151 patients with pathologically confirmed OP between January 2009 and September 2014, number of lesions, location, size, margin type, and consistency, as well as volume of lymphadenopathy and the presence and size of pleural effusions, were recorded...
October 20, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27742029/should-patients-with-obstructing-colorectal-cancer-have-proximal-diversion
#8
Chaya Shwaartz, Adam C Fields, Jake G Prigoff, Jeffrey J Aalberg, Celia M Divino
BACKGROUND: Up to 20% of patients with colorectal cancer present with obstruction. The goal of this study was to compare the short-term outcomes of patients with obstructing colon cancer who underwent resection and primary anastomosis with or without proximal diversion. METHODS: The American College of Surgeons' National Surgical Quality Improvement Program Procedure Targeted Colectomy databases from 2012 to 2014 were reviewed. Patients undergoing colorectal resection with or without diverting ostomy for obstructing colorectal cancer were analyzed...
September 2, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27738836/role-of-drain-placement-in-major-hepatectomy-a-nsqip-analysis-of-procedure-targeted-hepatectomy-cases
#9
Chaya Shwaartz, Adam C Fields, Jeffrey J Aalberg, Celia M Divino
BACKGROUND: The value of drain placement in hepatic surgery has not been conclusive. The aim of this study was to determine whether drain placement during major hepatectomy was associated with negative postoperative outcomes and whether its placement reduced the need for secondary procedures. METHODS: The American College of Surgeons National Surgical Quality Improvement Program Procedure-Targeted Hepatectomy Database was used to identify patients who underwent major hepatectomy...
October 13, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27737355/assessment-of-serum-copper-iron-and-immune-complexes-in-potentially-malignant-disorders-and-oral-cancer
#10
Ritu Tiwari, Chaya Manoranjini David, Datturao Ramanand Mahesh, Uma Sambargi, Kademadkal Javaraiah Rashmi, Prabhavati Benakanal
Potentially malignant disorders (PMDs) of oral cavity and oral cancer remain a cause of serious concern despite intensive research and development. Diet and immunity have been identified to play a crucial role as modifying factors in these diseases. Our study intended to explore this relationship by estimating and comparing the serum levels of copper, iron and circulating immune complexes (CICs) in patients diagnosed with PMDs and oral cancer and normal healthy individuals. In this study, 40 histopathologically diagnosed cases of PMDs and oral cancer were included along with 30 healthy controls and 5 ml of venous blood was drawn using venipuncture...
October 10, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27724977/mesenchymal-stem-cells-enhance-the-oncolytic-effect-of-newcastle-disease-virus-in-glioma-cells-and-glioma-stem-cells-via-the-secretion-of-trail
#11
Gila Kazimirsky, Wei Jiang, Shimon Slavin, Amotz Ziv-Av, Chaya Brodie
BACKGROUND: Newcastle disease virus (NDV) is an avian paramyxovirus, which selectively exerts oncolytic effects in cancer cells. Mesenchymal stem cells (MSCs) have been reported to affect tumor growth and deliver anti-tumor agents to experimental glioblastoma (GBM). Here, we explored the effects of NDV-infected MSCs derived from different sources, on glioma cells and glioma stem cells (GSCs) and the mechanisms involved in their effects. METHODS: The glioma cell lines (A172 and U87) and primary GSCs that were generated from GBM tumors were used in this study...
October 10, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27720990/design-principles-for-noninvasive-longitudinal-and-quantitative-cell-tracking-with-nanoparticle-based-ct-imaging
#12
Rinat Meir, Oshra Betzer, Menachem Motiei, Noam Kronfeld, Chaya Brodie, Rachela Popovtzer
Contradictory results in clinical trials are preventing the advancement and implementation of cell-based therapy. To explain such results, there is a need to uncover the mystery regarding the fate of the transplanted cells. To answer this need, we developed a technique for noninvasive in vivo cell tracking, which uses gold nanoparticles as contrast agents for CT imaging. Herein, we investigate the design principles of this technique for intramuscular transplantation of therapeutic cells. Longitudinal studies were performed, displaying the ability to track cells over long periods of time...
October 6, 2016: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/27707678/cutaneous-mycobacterium-massiliense-infection-after-body-piercing
#13
Hisashi Nomura, Takeru Funakoshi, Ayaka Chaya, Akiko Tanikawa, Yuji Miyamoto, Norihisa Ishii
No abstract text is available yet for this article.
October 6, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27683630/physical-rehabilitation-for-lung-transplant-candidates-and-recipients-an-evidence-informed-clinical-approach
#14
REVIEW
Lisa Wickerson, Dmitry Rozenberg, Tania Janaudis-Ferreira, Robin Deliva, Vincent Lo, Gary Beauchamp, Denise Helm, Chaya Gottesman, Polyana Mendes, Luciana Vieira, Margaret Herridge, Lianne G Singer, Sunita Mathur
Physical rehabilitation of lung transplant candidates and recipients plays an important in optimizing physical function prior to transplant and facilitating recovery of function post-transplant. As medical and surgical interventions in lung transplantation have evolved over time, there has been a demographic shift of individuals undergoing lung transplantation including older individuals, those with multiple co-morbidites, and candidates with respiratory failure requiring bridging to transplantation. These changes have an impact on the rehabilitation needs of lung transplant candidates and recipients...
September 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/27681595/loss-of-ift122-a-retrograde-intraflagellar-transport-ift-complex-component-leads-to-slow-progressive-photoreceptor-degeneration-due-to-inefficient-opsin-transport
#15
Meriam Boubakri, Taro Chaya, Hiromi Hirata, Naoko Kajimura, Ryusuke Kuwahara, Akiko Ueno, Jarema Malicki, Takahisa Furukawa, Yoshihiro Omori
In the retina, aberrant opsin transport from cell bodies to outer segments leads to retinal degenerative diseases such as retinitis pigmentosa. Opsin transport is facilitated by the intraflagellar transport (IFT) system that mediates the bidirectional movement of proteins within cilia. In contrast to functions of the anterograde transport executed by IFT complex B (IFT-B), the precise functions of the retrograde transport mediated by IFT complex A (IFT-A) have not been well studied in photoreceptor cilia. Here, we analyzed developing zebrafish larvae carrying a null mutation in ift122 encoding a component of IFT-A...
November 18, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27556063/renal-transplantation-related-risk-factors-for-the-development-of-uterine-adenomatoid-tumors
#16
Teruyuki Mizutani, Osamu Yamamuro, Noriko Kato, Kazumasa Hayashi, Junya Chaya, Norihiko Goto, Toyonori Tsuzuki
•We analyzed the epidemiological factors for clinical manifestations of uterine adenomatoid tumors.•Renal transplantation with immunosuppression therapy is risk factor for the development of uterine adenomatoid tumors.•The length of time on dialysis is risk factor for the development of uterine adenomatoid tumors.
August 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27550519/arhgef10-directs-the-localization-of-rab8-to-rab6-positive-executive-vesicles
#17
Satoshi Shibata, Tsubasa Kawanai, Takayuki Hara, Asuka Yamamoto, Taro Chaya, Yasunori Tokuhara, Chinami Tsuji, Manabu Sakai, Taro Tachibana, Shinobu Inagaki
The function of ARHGEF10, a known guanine nucleotide exchange factor (GEF) for RhoA with proposed roles in various diseases, is poorly understood. To understand the precise function of this protein, we raised a monoclonal antibody against ARHGEF10 and determined its localization in HeLa cells. ARHGEF10 was found to localize to vesicles containing Rab6 (of which there are three isoforms, Rab6a, Rab6b and Rab6c), Rab8 (of which there are two isoforms, Rab8a and Rab8b), and/or the secretion marker neuropeptide Y (NPY)-Venus in a Rab6-dependent manner...
October 1, 2016: Journal of Cell Science
https://www.readbyqxmd.com/read/27530428/the-interplay-between-chromosome-stability-and-cell-cycle-control-explored-through-gene-gene-interaction-and-computational-simulation
#18
Jesse P Frumkin, Biranchi N Patra, Anthony Sevold, Kumkum Ganguly, Chaya Patel, Stephanie Yoon, Molly B Schmid, Animesh Ray
Chromosome stability models are usually qualitative models derived from molecular-genetic mechanisms for DNA repair, DNA synthesis, and cell division. While qualitative models are informative, they are also challenging to reformulate as precise quantitative models. In this report we explore how (A) laboratory experiments, (B) quantitative simulation, and (C) seriation algorithms can inform models of chromosome stability. Laboratory experiments were used to identify 19 genes that when over-expressed cause chromosome instability in the yeast Saccharomyces cerevisiae To better understand the molecular mechanisms by which these genes act, we explored their genetic interactions with 18 deletion mutations known to cause chromosome instability...
September 30, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27496549/two-transgenic-mouse-models-for-%C3%AE-subunit-components-of-succinate-coa-ligase-yielding-pleiotropic-metabolic-alterations
#19
Gergely Kacso, Dora Ravasz, Judit Doczi, Beáta Németh, Ory Madgar, Ann Saada, Polina Ilin, Chaya Miller, Elsebet Ostergaard, Iordan Iordanov, Daniel Adams, Zsuzsanna Vargedo, Masatake Araki, Kimi Araki, Mai Nakahara, Haruka Ito, Aniko Gál, Mária J Molnár, Zsolt Nagy, Attila Patocs, Vera Adam-Vizi, Christos Chinopoulos
Succinate-CoA ligase (SUCL) is a heterodimer enzyme composed of Suclg1 α-subunit and a substrate-specific Sucla2 or Suclg2 β-subunit yielding ATP or GTP, respectively. In humans, the deficiency of this enzyme leads to encephalomyopathy with or without methylmalonyl aciduria, in addition to resulting in mitochondrial DNA depletion. We generated mice lacking either one Sucla2 or Suclg2 allele. Sucla2 heterozygote mice exhibited tissue- and age-dependent decreases in Sucla2 expression associated with decreases in ATP-forming activity, but rebound increases in cardiac Suclg2 expression and GTP-forming activity...
October 15, 2016: Biochemical Journal
https://www.readbyqxmd.com/read/27487314/should-sabbath-prohibitions-be-overridden-to-provide-emotional-support-to-a-sick-relative
#20
REVIEW
Chaya Greenberger, Pnina Mor
BACKGROUND: There is a consensus among the halachic authorities that life-saving actions override Sabbath prohibitions. They are painstaking in securing that the sanctity of the Sabbath is maintained but that not a single life be lost. OBJECTIVE: This manuscript examines if and when a relative's presence at the bedside of a seriously ill individual is potentially life-saving against the backdrop of the scientific literature. It specifically addresses the permissibility of traveling in a motorized vehicle, generally prohibited on the Sabbath, to be with one's relative in hospital for the provision of emotional support...
2016: Rambam Maimonides Medical Journal
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