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https://www.readbyqxmd.com/read/28498901/ecco-escp-consensus-on-surgery-for-crohn-s-disease
#1
Willem A Bemelman, Janindra Warusavitarne, Gianluca M Sampietro, Zuzana Serclova, Oded Zmora, Gaetano Luglio, Anthony de Buck van Overstraeten, John P Burke, Christianne J Buskens, Colombo Francesco, Jorge Amil Dias, Rami Eliakim, Tomás Elosua, I Ethem Gecim, Sanja Kolacek, Jaroslaw Kierkus, Kaija-Leena Kolho, Jérémie H Lefevre, Monica Millan, Yves Panis, Thomas Pinkney, Richard K Russell, Chaya Shwaartz, Carolynne Vaizey, Nuha Yassin, André D'Hoore
No abstract text is available yet for this article.
May 11, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28423669/the-novel-long-non-coding-rna-talnec2-regulates-tumor-cell-growth-and-the-stemness-and-radiation-response-of-glioma-stem-cells
#2
Shlomit Brodie, Hae Kyung Lee, Wei Jiang, Simona Cazacu, Cunli Xiang, Laila M Poisson, Indrani Datta, Steve Kalkanis, Doron Ginsberg, Chaya Brodie
Despite advances in novel therapeutic approaches for the treatment of glioblastoma (GBM), the median survival of 12-14 months has not changed significantly. Therefore, there is an imperative need to identify molecular mechanisms that play a role in patient survival. Here, we analyzed the expression and functions of a novel lncRNA, TALNEC2 that was identified using RNA seq of E2F1-regulated lncRNAs. TALNEC2 was localized to the cytosol and its expression was E2F1-regulated and cell-cycle dependent. TALNEC2 was highly expressed in GBM with poor prognosis, in GBM specimens derived from short-term survivors and in glioma cells and glioma stem cells (GSCs)...
May 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423529/pif-promotes-brain-re-myelination-locally-while-regulating-systemic-inflammation-clinically-relevant-multiple-sclerosis-m-smegmatis-model
#3
Giuseppe Migliara, Martin Mueller, Alessia Piermattei, Chaya Brodie, Michael J Paidas, Eytan R Barnea, Francesco Ria
Neurologic disease diagnosis and treatment is challenging. Multiple Sclerosis (MS) is a demyelinating autoimmune disease with few clinical forms and uncertain etiology. Current studies suggest that it is likely caused by infection(s) triggering a systemic immune response resulting in antigen/non-antigen-related autoimmune response in central nervous system (CNS). New therapeutic approaches are needed. Secreted by viable embryos, PreImplantation Factor (PIF) possesses a local and systemic immunity regulatory role...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28417551/morbidity-and-mortality-after-treatment-of-ewing-sarcoma-a-single-institution-experience
#4
Danielle Novetsky Friedman, Katherine Chastain, Joanne F Chou, Chaya S Moskowitz, Roberto Adsuar, Leonard H Wexler, Alexander J Chou, Amelia DeRosa, Joanne Candela, Heather Magnan, Shawn Pun, Tamara Kahan, Suzanne L Wolden, Paul A Meyers, Kevin C Oeffinger
BACKGROUND: Children, adolescents, and young adults treated for Ewing sarcoma (ES) are at risk for disease-related and treatment-related complications. We aimed to describe early and late overall mortality, cause-specific mortality, and key adverse health outcomes in a large, single-institutional cohort of patients with ES. METHODS: Patients with ES diagnosed at age less than 40 years and treated at Memorial Sloan Kettering between 1974 and 2012 were included. Overall survival was estimated using Kaplan-Meier methods...
April 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28339329/morbidity-and-mortality-associated-with-meningioma-after-cranial-radiotherapy-a-report-from-the-childhood-cancer-survivor-study
#5
Daniel C Bowers, Chaya S Moskowitz, Joanne F Chou, Claire M Mazewski, Joseph P Neglia, Gregory T Armstrong, Wendy M Leisenring, Leslie L Robison, Kevin C Oeffinger
Purpose Little is known about neurologic morbidity attributable to cranial radiotherapy (CRT) -associated meningiomas. Materials and Methods From 4,221 survivors exposed to CRT in the Childhood Cancer Survivor Study, a diagnosis of meningioma and onset of neurologic sequelae were ascertained. Cox proportional hazards regression was used to estimate hazard ratios (HR) and 95% CIs to evaluate the factors associated with neurologic sequelae after subsequent meningioma. Results One hundred ninety-nine meningiomas were identified among 169 participants...
May 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28298280/nutritional-recommendations-for-adult-bariatric-surgery-patients-clinical-practice
#6
REVIEW
Shiri Sherf Dagan, Ariela Goldenshluger, Inbal Globus, Chaya Schweiger, Yafit Kessler, Galit Kowen Sandbank, Tair Ben-Porat, Tali Sinai
Bariatric surgery is currently the most effective treatment for morbid obesity and its associated metabolic complications. To ensure long-term postoperative success, patients must be prepared to adopt comprehensive lifestyle changes. This review summarizes the current evidence and expert opinions with regard to nutritional care in the perioperative and long-term postoperative periods. A literature search was performed with the use of different lines of searches for narrative reviews. Nutritional recommendations are divided into 3 main sections: 1) presurgery nutritional evaluation and presurgery diet and supplementation; 2) postsurgery diet progression, eating-related behaviors, and nutritional therapy for common gastrointestinal symptoms; and 3) recommendations for lifelong supplementation and advice for nutritional follow-up...
March 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28225661/lgbtq-youth-part-1
#7
Tracy Perron, Connie Kartoz, Chaya Himelfarb
In order to provide holistic care, school nurses must be culturally competent by being sensitive to health disparities experienced by students in at-risk populations. Despite the growing acceptance toward gender and sexual minorities, LGBTQ youth remain an at-risk population in our communities and our schools. School nurses as well as school counselors, social workers, and psychologists can increase their cultural competence in caring for this group of students by increasing their understanding of appropriate terminology and risks associated with this vulnerable group...
March 2017: NASN School Nurse
https://www.readbyqxmd.com/read/28225658/lgbtq-part-2
#8
Tracy Perron, Connie Kartoz, Chaya Himelfarb
In addition to dealing with the normal challenges of being a teenager, many times LGBTQ youth have to deal with harassment, intimidation, and bullying on a daily basis as they disproportionately experience verbal and physical harassment while in school as a result of their sexual orientation and/or gender identity. This violence adversely affects these students' health and well-being as reflected in the depression and suicide rate among LGBTQ youth. As Part 2 of a series in articles on caring for LGBTQ youth in a school setting, this article reviews specific health risks in this group of students...
March 2017: NASN School Nurse
https://www.readbyqxmd.com/read/28225320/park-prescription-dc-park-rx-a-new-strategy-to-combat-chronic-disease-in-children
#9
Robert Zarr, Linda Cottrell, Chaya Merrill
No abstract text is available yet for this article.
January 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28222400/antiprotozoal-antimycobacterial-and-anti-inflammatory-evaluation-of-cnidoscolus-chayamansa-mc-vaugh-extract-and-the-isolated-compounds
#10
Mariana Z Pérez-González, Gabriel A Gutiérrez-Rebolledo, Lilián Yépez-Mulia, Irma S Rojas-Tomé, Julieta Luna-Herrera, María A Jiménez-Arellanes
Cnidoscolus chayamansa is a medicinal and edible plant known as Chaya, is commonly used as an anti-inflammatory, antiprotozoal, antibacterial agent and as a remedy for respiratory illness, gastrointestinal disorders, and vaginal infections related with the inflammation process. In this paper, we describe the plant's phytochemical analysis and biological activities (antimycobacterial, antibacterial, antiprotozoal, and anti-inflammatory properties) of the CHCl3:MeOH (1:1) leaves extract and isolated compounds, as well as the acute and sub-acute toxic effects...
May 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28123285/sexual-dimorphism-in-foramen-magnum-dimensions-in-the-south-indian-population-a-digital-submentovertex-radiographic-study
#11
Neha Ajit Raikar, Manasa A Meundi, Chaya M David, Mahesh Dathu Rao, Sanjay Chikkarasinakere Jogigowda
PURPOSE OF THE STUDY: Personal identification is a vital arena of forensic investigation, facilitating the search for missing persons. This process of identification is eased by the determination of age, sex, and ethnicity. In situations where there are fragmented and mutilated skeletal remains, sex determination is relatively difficult, and it becomes important to establish the accuracy of individual bones. AIM: This study aims to evaluate sexual dimorphism in foramen magnum (FM) dimensions in the South Indian population using digital submentovertex (SMV) radiograph...
September 2016: Journal of Forensic Dental Sciences
https://www.readbyqxmd.com/read/28115485/ick-ciliary-kinase-is-essential-for-planar-cell-polarity-formation-in-inner-ear-hair-cells-and-hearing-function
#12
Shio Okamoto, Taro Chaya, Yoshihiro Omori, Ryusuke Kuwahara, Shun Kubo, Hirofumi Sakaguchi, Takahisa Furukawa
Cellular asymmetries play crucial roles in development and organ function. The planar cell polarity (PCP) signaling pathway is involved in the establishment of cellular asymmetry within the plane of a cell sheet. Inner ear sensory hair cells, which have several rows of staircase-like stereocilia and one kinocilium located at the vertex of the stereocilia protruding from the apical surface of each hair cell, exhibit a typical form of PCP. While connections between cilia and PCP signaling in vertebrate development have been reported, their precise nature is not well understood...
January 23, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28111814/testosterone-serum-profile-semen-characteristics-and-testicular-biometry-of-mangalarga-marchador-stallions-in-a-tropical-environment
#13
B Waddington, J M Penitente-Filho, Jgs Neves, R O Pinho, A Y Chaya, P P Maitan, C O Silveira, M G Neves, Sef Guimarães, G R de Carvalho, J D Guimarães
This study was conducted to characterize the daily profile of testosterone secretion and its mean concentrations in the four seasons as well as to evaluate the semen characteristics and testicular biometry of Mangalarga Marchador stallions throughout the year in a tropical region. Three stallions were submitted to semen collections and evaluation of testicular biometry every 14 days along a year. Blood samples were collected once at the middle of each season, in a 20-min interval during 24 hr in order to evaluate the testosterone secretion profiles among seasons...
January 23, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28097399/segregation-for-fertility-and-meiotic-stability-in-novel-brassica-allohexaploids
#14
Margaret W Mwathi, Mehak Gupta, Chaya Atri, Surinder S Banga, Jacqueline Batley, Annaliese S Mason
Allohexaploid Brassica populations reveal ongoing segregation for fertility, while genotype influences fertility and meiotic stability. Creation of a new Brassica allohexaploid species is of interest for the development of a crop type with increased heterosis and adaptability. At present, no naturally occurring, meiotically stable Brassica allohexaploid exists, with little data available on chromosome behaviour and meiotic control in allohexaploid germplasm. In this study, 100 plants from the cross B. carinata × B...
April 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28095036/differentiation-of-clear-cell-renal-cell-carcinoma-from-other-renal-cortical-tumors-by-use-of-a-quantitative-multiparametric-mri-approach
#15
Andreas M Hötker, Yousef Mazaheri, Andreas Wibmer, Christoph A Karlo, Junting Zheng, Chaya S Moskowitz, Satish K Tickoo, Paul Russo, Hedvig Hricak, Oguz Akin
OBJECTIVE: The purpose of this study was to develop a quantitative multiparametric MRI approach to differentiating clear cell renal cell carcinoma (RCC) from other renal cortical tumors. MATERIALS AND METHODS: This retrospective study included 119 patients with 124 histopathologically confirmed renal cortical tumors who underwent preoperative MRI including DWI, contrast-enhanced, and chemical-shift sequences before nephrectomy. Two radiologists independently assessed each tumor volumetrically, and apparent diffusion coefficient values, parameters from multiphasic contrast-enhanced MRI (peak enhancement, upslope, downslope, AUC), and chemical-shift indexes were calculated...
March 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28040534/cardiovascular-risk-factors-in-survivors-of-childhood-hematopoietic-cell-transplantation-treated-with-total-body-irradiation-a-longitudinal-analysis
#16
Danielle Novetsky Friedman, Patrick Hilden, Chaya S Moskowitz, Maya Suzuki, Farid Boulad, Nancy A Kernan, Suzanne L Wolden, Kevin C Oeffinger, Charles A Sklar
Hematopoietic cell transplantation (HCT) survivors treated with total body irradiation (TBI) are known to be at increased risk for the development of cardiovascular risk factors (CVRFs). We sought to characterize the incidence of CVRFs in a TBI-exposed survivor cohort and to describe prognostic indicators of their development through a retrospective analysis of CVRFs in 1-year survivors of leukemia or lymphoma treated with TBI at Memorial Sloan Kettering between April 1987 and May 2011. Eligible participants were age ≤21 years at the time of TBI and were not receiving glucocorticoid therapy at the time of entry to long-term follow-up...
March 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28028762/screening-for-thyroid-cancer-in-survivors-of-childhood-and-young-adult-cancer-treated-with-neck-radiation
#17
Emily S Tonorezos, Dana Barnea, Chaya S Moskowitz, Joanne F Chou, Charles A Sklar, Elena B Elkin, Richard J Wong, Duan Li, R Michael Tuttle, Deborah Korenstein, Suzanne L Wolden, Kevin C Oeffinger
BACKGROUND: The optimal method of screening for thyroid cancer in survivors of childhood and young adult cancer exposed to neck radiation remains controversial. Outcome data for a physical exam-based screening approach are lacking. METHODS: We conducted a retrospective review of adult survivors of childhood and young adult cancer with a history of neck radiation followed in the Adult Long-Term Follow-Up Clinic at Memorial Sloan Kettering between November 2005 and August 2014...
June 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28012356/radiogenomic-evaluation-of-lung-cancer-are-there-imaging-characteristics-associated-with-lung-adenocarcinomas-harboring-braf-mutations
#18
Darragh F Halpenny, Andrew Plodkowski, Gregory Riely, Junting Zheng, Anya Litvak, Chaya Moscowitz, Michelle S Ginsberg
INTRODUCTION: We studied computed tomography (CT) features associated with BRAF mutated lung cancer. MATERIALS AND METHODS: CT features of BRAF mutated lung cancers were compared to stage matched lesions without BRAF mutation. RESULTS: 47 (25%) patients with BRAF mutation and 141 (75%) without BRAF mutation were included. BRAF lesions were most frequently solid 37 (84%), spiculated 22 (50%), and peripheral 37 (84%). No feature of the primary tumor was significantly different between BRAF and non-BRAF groups...
March 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28008695/family-members-experience-of-intensive-care-unit-support-group-qualitative-analysis-of-intervention
#19
Dvora Kirshbaum-Moriah, Chaya Harel, Julie Benbenishty
BACKGROUND: Family members of intensive care unit patients develop anxiety, depression and/or symptoms suggestive of risk for post-traumatic stress. Nurse-led support groups have been recommended and used in a variety of settings as a mechanism to help meet family needs and overcome challenges. These groups have been reported to increase the members' understanding of complex medical issues involved in their situations and to be helpful in identifying practical coping mechanisms. AIM: To investigate the experiences of family members participating in a nurse-social worker led support group in the intensive care unit...
December 22, 2016: Nursing in Critical Care
https://www.readbyqxmd.com/read/27936421/catheter-directed-endovascular-application-of-thrombin-report-of-3-cases-and-review-of-the-literature
#20
Majid Maybody, David C Madoff, Raymond H Thornton, Steven A Morales, Chaya S Moskowitz, Meier Hsu, Lynn A Brody, Karen T Brown, Anne M Covey
PURPOSE: To report 3 new cases of catheter-directed endovascular application of thrombin and explore trends by analysis of published case series. MATERIALS AND METHODS: Institutional Review Board approved this retrospective study. All cases of non-tumoral arterial embolization performed from January 2003 to January 2015 at our institution were retrospectively reviewed. Thrombin was used in 7 of 589 cases. In 3 cases intra arterial thrombin was injected via catheter to treat active hemorrhage...
March 2017: Clinical Imaging
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