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https://www.readbyqxmd.com/read/29775479/acute-intermittent-hypoxia-and-rehabilitative-training-following-cervical-spinal-injury-alters-neuronal-hypoxia-and-plasticity-associated-protein-expression
#1
Atiq Hassan, Breanna M Arnold, Sally Caine, Behzad M Toosi, Valerie M K Verge, Gillian D Muir
One of the most promising approaches to improve recovery after spinal cord injury (SCI) is the augmentation of spontaneously occurring plasticity in uninjured neural pathways. Acute intermittent hypoxia (AIH, brief exposures to reduced O2 levels alternating with normal O2 levels) initiates plasticity in respiratory systems and has been shown to improve recovery in respiratory and non-respiratory spinal systems after SCI in experimental animals and humans. Although the mechanism by which AIH elicits its effects after SCI are not well understood, AIH is known to alter protein expression in spinal neurons in uninjured animals...
2018: PloS One
https://www.readbyqxmd.com/read/29754119/a-pilot-study-and-brief-overview-of-rehabilitation-via-virtual-environment-in-patients-suffering-from-dementia
#2
Th Fasilis, P Patrikelis, A Siatouni, A Alexoudi, A Veretzioti, L Zachou, S-St Gatzonis
Dementia is one of the increasing problems of modern societies. The immediate cure is not a possible solution, at least at the moment, but science has found a number of new ways to retard and under specific conditions to halt its development. A potential, and constantly evolving scientific field is the use of Computerized Cognitive Rehabilitation (CCR) and Virtual Environments (Vr.E). According to the existing literature, subjecting patients to various neuro-rehabilitative conditions within 3D virtual environments, allows them to obtain significant therapeutic benefits in which both transferability and durations over time are observed, in relation to the training period of the intervention...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29751956/relation-of-postexercise-reduction-of-arterial-blood-pressure-and-erectile-dysfunction-in-patients-with-coronary-heart-disease
#3
Dariusz Kałka, Jana Gebala, Lesław Rusiecki, Ryszard Smoliński, Jakub Dulanowski, Małgorzata Rusiecka, Anna Biełous-Wilk, Witold Pilecki, Krzysztof Womperski, Romuald Zdrojowy
Penile erection is a hemodynamic process consisting of 2 synchronized components in which the first (active) requires proper vascular endothelium functioning, whereas the second one (passive) is based on a veno-occlusive mechanism. Antihypertensive treatment reduces the passive component, often leading to the development of erectile dysfunction (ED), but lifestyle modifications can improve the sexual functioning. The study aimed to evaluate the association between blood pressure (BP) reduction caused by cardiovascular training and the intensity of ED in men with coronary heart disease...
April 18, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29746348/homeless-status-postdischarge-health-care-utilization-and-readmission-after-surgery
#4
Ashley Titan, Laura Graham, Amy Rosen, Kamal Itani, Laurel A Copeland, Hillary J Mull, Edith Burns, Joshua Richman, Stefan Kertesz, Tyler Wahl, Melanie Morris, Jeffery Whittle, Gordon Telford, Mark Wilson, Mary Hawn
INTRODUCTION: Homeless Veterans are vulnerable to poor care transitions, yet little research has examined their risk of readmission following inpatient surgery. This study investigates the predictors of surgical readmission among homeless relative to housed Veteran patients. METHODS: Inpatient general, vascular, and orthopedic surgeries occurring in the Veterans Health Administration from 2008 to 2014 were identified. Administrative International Classification of Diseases, Ninth Revision, Clinical Modification codes and Veterans Health Administration clinic stops were used to identify homeless patients...
June 2018: Medical Care
https://www.readbyqxmd.com/read/29721510/evaluation-of-skeletal-muscle-function-and-effects-of-early-rehabilitation-during-acute-heart-failure-rationale-and-study-design
#5
Kinga Węgrzynowska-Teodorczyk, Agnieszka Siennicka, Krystian Josiak, Robert Zymliński, Monika Kasztura, Waldemar Banasiak, Piotr Ponikowski, Marek Woźniewski
Background: Acute heart failure (AHF) is associated with disturbances of the peripheral perfusion leading to the dysfunction of many organs. Consequently, an episode of AHF constitutes a "multiple organ failure" which may also affect the skeletal muscles. However, the abnormalities within skeletal muscles during AHF have not been investigated so far. The aim of this project is to comprehensively evaluate skeletal muscles (at a functional and tissue level) during AHF. Methods: The study will include ≥63 consecutive AHF patients who will be randomized into 2 groups: ≥42 with cardiac rehabilitation group versus ≥21 with standard pharmacotherapy alone...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29706822/high-intensity-sport-specific-cardiac-rehabilitation-training-of-a-22-year-old-competitive-cyclist-after-spontaneous-coronary-artery-dissection
#6
Nicholas Weber, Adam Weber, Pasquale Carbone, Anne Lawrence, Tim Bilbrey, Jeffrey M Schussler, Jenny Adams
A 22-year-old man with spontaneous coronary artery dissection wanted to assess the feasibility of returning to competitive cycling. He was referred to the cardiac rehabilitation (CR) program at Baylor Hamilton Heart and Vascular Hospital where staff designed a high-intensity, sport-specific training program that simulated the movements and forces associated with his goal activity. The program was symptom limited and enabled the patient to train earlier and at a higher intensity than is typically allowed in conventional CR programs...
April 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29696208/study-protocol-for-the-fitr-heart-study-feasibility-safety-adherence-and-efficacy-of-high-intensity-interval-training-in-a-hospital-initiated-rehabilitation-program-for-coronary-heart-disease
#7
Jenna Taylor, Shelley E Keating, Michael D Leveritt, David J Holland, Sjaan R Gomersall, Jeff S Coombes
Background: For decades, moderate intensity continuous training (MICT) has been the cornerstone of exercise prescription for cardiac rehabilitation (CR). High intensity interval training (HIIT) is now recognized in CR exercise guidelines as an appropriate and efficient modality for improving cardiorespiratory fitness, a strong predictor of mortality. However, the clinical application of HIIT in a real world CR setting, in terms of feasibility, safety, and long-term adherence, needs further investigation to address ongoing reservations...
December 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29686560/specificity-of-training-in-cardiac-rehabilitation-to-facilitate-a-patient-s-return-to-strenuous-work-following-aortic-valve-replacement
#8
Nicole Jenkins, Jenny Adams, Tim Bilbrey, Stephanie McCray, Jeffrey M Schussler
A 30-year-old male roughneck worker on an oil rig underwent aortic valve replacement and subsequently enrolled in the Baylor Heart and Vascular Hospital exercise-based cardiac rehabilitation (CR) program. He expressed a strong desire to return to his physically demanding job. Based on his unique job requirements, CR staff designed and implemented comprehensive tests and a 5-week specific physical training program that included 6 exercises simulating his job functions. The selected exercises are not typically prescribed in traditional CR programs but mimicked the muscular strength/endurance required to perform his job...
January 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29682756/satisfaction-with-life-in-individuals-with-a-lower-limb-amputation-the-importance-of-active-coping-and-acceptance
#9
M Graça Pereira, Cristiana Ramos, Armanda Lobarinhas, J Cunha Machado, Susana Pedras
The aim of this study was to analyze the relationship between sociodemographic/clinical characteristics, coping strategies and satisfaction with life in individuals with lower limb amputation. Sixty-three individuals with a lower limb amputation due to Diabetes and Peripheral Vascular Disease participated in the study and answered measures of coping strategies and satisfaction with life. Findings revealed high dissatisfaction with life. Acceptance and active coping were the most used coping strategies. Satisfaction with life was positively associated with active and planning coping, religion, acceptance and humour...
April 17, 2018: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/29656899/long-term-outcome-of-patients-with-or-without-osseointegrated-implants-after-resection-of-mandibular-ameloblastoma-and-reconstruction-with-vascularized-bone-graft-functional-assessment-and-quality-of-life
#10
Marco Pappalardo, Chung-Kan Tsao, Man Lung Tsang, Jie Zheng, Yang-Ming Chang, Chi-Ying Tsai
BACKGROUND: The optimal management after the resection of mandibular ameloblastoma has been very challenging to surgeons. The aim of this study is to evaluate the functional, aesthetic, and quality of life outcomes of patients who had a segmental mandibular resection and immediate reconstruction with or without osseointegrated implants. METHOD: Patients' demographics, tumor characteristics, treatment, and complications were retrieved. Patients were divided into two groups: dental rehabilitated vs...
March 28, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29655872/-contribution-of-the-scrotal-flap-for-the-coverage-of-ischial-and-perineal-pressure-ulcers
#11
M Vantomme, R Viard, R Aimard, P-L Vincent, J-P Comparin, D Voulliaume
INTRODUCTION: The ischiatric pressure sore is a common pathology in rehabilitated spinal cord injured people, despite careful prevention. Medical treatment by discharge and directed healing is not always sufficient and surgery using local musculocutaneous flaps is often essential. Unfortunately, recidivism is frequent and the availability of local flaps is limited. The scrotal flap is an excellent complement to classic flaps, gluteal flaps or hamstrings. It can be used alone or in addition to another musculocutaneous flap, in first or second intention...
April 11, 2018: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29649992/protocol-for-promoting-recovery-optimization-of-walking-activity-in-stroke-prowalks-a-randomized-controlled-trial
#12
Henry Wright, Tamara Wright, Ryan T Pohlig, Scott E Kasner, Jonathan Raser-Schramm, Darcy Reisman
BACKGROUND: Stroke survivors are more physically inactive than even the most sedentary older adults, and low activity is associated with increased risk of recurrent stroke, medical complications, and mortality. We hypothesize that the combination of a fast walking intervention that improves walking capacity, with a step activity monitoring program that facilitates translation of gains from the clinic to the "real-world", would generate greater improvements in real world walking activity than with either intervention alone...
April 12, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29626613/comparing-the-effects-of-dual-task-gait-testing-in-new-and-established-ambulators-with-lower-extremity-amputations
#13
Courtney Frengopoulos, Michael Wc Payne, Jeffrey D Holmes, Ricardo Viana, Susan W Hunter
BACKGROUND: Gait is a complex process that involves coordinating motor and sensory systems through higher-order cognitive processes. Walking with a prosthesis after lower extremity amputation challenges these processes. However, the factors that influence the cognitive-motor interaction in gait among lower extremity amputees has not been evaluated. To assess the interaction of cognition and mobility, individuals must be evaluated using the dual-task paradigm. OBJECTIVE: To investigate the effect of etiology and time with prosthesis on dual-task performance in those with lower extremity amputations...
April 4, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29622289/continuity-defects-of-the-mandible-comparison-of-three-techniques-for-osseous-reconstruction-and-their-impact-on-implant-loading
#14
Yunus Okcu, Jan Rustemeyer
Computer-aided design/manufacturing (CAD/CAM) is now widely used, but whether it can help to overcome complications in mandibular reconstruction and accelerate dental implantation is still a matter for debate. Therefore, we aimed to evaluate the benefits of this technique using vascularized iliac crest or fibula flaps in mandibular reconstruction, with respect to the time between reconstruction and implantation, and the ratio of planned to inserted implants. We reviewed retrospectively the records of 54 patients who underwent mandibular reconstructions between 2012 and 2016, and included in our study the last 10 cases representing each of the following groups: iliac crest flap with CAD/CAM (Group 1); fibula flap with CAD/CAM (Group 2); and fibula flap without CAD/CAM (Group 3)...
March 9, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29619293/in-vivo-photoacoustic-imaging-of-brain-injury-and-rehabilitation-by-high-efficient-near-infrared-dye-labeled-mesenchymal-stem-cells-with-enhanced-brain-barrier-permeability
#15
Weitao Li, Ronghe Chen, Jing Lv, Hongke Wang, Yu Liu, Ya Peng, Zhiyu Qian, Guo Fu, Liming Nie
Stem cell migration and interaction with pathology are critical to understand the complexity and status of disease recovery progress. However, the dynamic visualization still remains a great challenge due to imaging technical limitation, cell labeling difficulty, or blood-brain barrier (BBB). Herein, fast photoacoustic tomography (PAT) with optical molecular probes is applied to noninvasively monitor traumatic brain injury (TBI) and its rehabilitation. The vascular distribution and TBI hemorrhage are clearly imaged, longitudinally monitored, and quantified...
February 2018: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/29617186/determining-raptor-species-and-tissue-sensitivity-for-improved-west-nile-virus-surveillance
#16
Kendall L Kritzik, Gail Kratz, Nicholas A Panella, Kristen Burkhalter, Rebecca J Clark, Brad J Biggerstaff, Nicholas Komar
  Raptors are a target sentinel species for West Nile virus (WNV) because many are susceptible to WNV disease, they are easily sighted because of their large size, and they often occupy territories near human settlements. Sick and dead raptors accumulate at raptor and wildlife rehabilitation clinics. However, investigations into species selection and specimen type for efficient detection of WNV are lacking. Accordingly, we evaluated dead raptors from north-central Colorado and SE Wyoming over a 4-yr period...
April 4, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29609890/increasing-circulating-sphingosine-1-phosphate-attenuates-lung-injury-during-ex-vivo-lung-perfusion
#17
J Hunter Mehaffey, Eric J Charles, Adishesh K Narahari, Sarah Schubert, Victor E Laubach, Nicholas R Teman, Kevin R Lynch, Irving L Kron, Ashish K Sharma
BACKGROUND: Sphingosine-1-phosphate regulates endothelial barrier integrity and promotes cell survival and proliferation. We hypothesized that upregulation of sphingosine-1-phosphate during ex vivo lung perfusion would attenuate acute lung injury and improve graft function. METHODS: C57BL/6 mice (n = 4-8/group) were euthanized, followed by 1 hour of warm ischemia and 1 hour of cold preservation in a model of donation after cardiac death. Subsequently, mice underwent 1 hour of ex vivo lung perfusion with 1 of 4 different perfusion solutions: Steen solution (Steen, control arm), Steen with added sphingosine-1-phosphate (Steen + sphingosine-1-phosphate), Steen plus a selective sphingosine kinase 2 inhibitor (Steen + sphingosine kinase inhibitor), or Steen plus both additives (Steen + sphingosine-1-phosphate + sphingosine kinase inhibitor)...
March 11, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29602721/efficacy-and-safety-of-tadalafil-5-mg-once-daily-for-the-treatment-of-erectile-dysfunction-after-robot-assisted-laparoscopic-radical-prostatectomy-a-2-year-follow-up
#18
Soodong Kim, Gyung Tak Sung
BACKGROUND: Although nerve-sparing robot-assisted radical prostatectomy (NS-RALP) is performed, a large number of patients still experience erectile dysfunction (ED) after surgery. AIM: To evaluate the efficacy and safety of tadalafil 5 mg once daily (OaD) in ED treatment over 2 years and investigate the cause of vascular ED after NS-RARP. METHODS: We retrospectively evaluated 95 men who underwent NS-RARP and had a penile rehabilitation treatment with tadalafil 5 mg OaD...
March 27, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29600086/exercise-training-in-pulmonary-arterial-hypertension
#19
REVIEW
Laura Adelaide Dalla Vecchia, Maurizio Bussotti
Pulmonary arterial hypertension (PAH) is characterized by a continuous increase in pre-capillary pulmonary vascular resistance (PVR) with a progressive reduction of cardiac output (CO). Similar to what occurs in left heart failure (HF), this represents the initial phase of a syndrome characterized by the progressive development of dyspnea and fatigue with increasing deterioration of exercise tolerance. Although the therapies introduced in the last two decades have determined a significant improvement of the clinical conditions of PAH patients, they have a little impact on exercise capacity and prognosis...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29570835/influence-of-diabetes-on-tissue-healing-in-orthopedic-injuries
#20
REVIEW
Artur Stolarczyk, Sylwia Sarzyńska, Agata Gondek, Agnieszka Cudnoch-Jędrzejewska
Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from the defective action or secretion of insulin. Chronic hyperglycemia can lead to the damage, dysfunction and failure of various organs. In the context of complications of healing and orthopedic rehabilitation, vascular (microangiopathy) and nerve (neuropathy) disorders deserve particular attention. About 12% of the patients admitted to orthopedic departments have diabetes. Studies indicate that there is an indisputable link between diabetes and: an increased risk of fractures, the difficult healing of injuries of bones, ligaments and musculotendinous...
March 23, 2018: Clinical and Experimental Pharmacology & Physiology
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