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https://www.readbyqxmd.com/read/29691249/hypertensive-pregnancy-complications-in-women-with-epilepsy-and-antiepileptic-drugs-a-population-based-cohort-study-of-first-pregnancies-in-norway
#1
Kim Christian Danielsson, Ingrid Borthen, Nils-Halvdan Morken, Nils Erik Gilhus
OBJECTIVES: To estimate the risk of hypertensive pregnancy complications in women with epilepsy, with and without antiepileptic drugs, and assess the risk associated with the four most common antiepileptic drugs. DESIGN: A population-based cohort study using linked data from the Medical Birth Registry of Norway and the Norwegian Prescription Database. Women with epilepsy with and without antiepileptic drugs were compared with women without epilepsy. SETTING: Norway, 2004-2012...
April 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29691216/the-usability-and-effectiveness-of-mobile-health-technology-based-lifestyle-and-medical-intervention-apps-supporting-health-care-during-pregnancy-systematic-review
#2
REVIEW
Sanne B Overdijkink, Adeline V Velu, Ageeth N Rosman, Monique Dm van Beukering, Marjolein Kok, Regine Pm Steegers-Theunissen
BACKGROUND: A growing number of mobile health (mHealth) technology-based apps are being developed for personal lifestyle and medical health care support, of which several apps are related to pregnancy. Evidence on usability and effectiveness is limited but crucial for successful implementation. OBJECTIVE: This study aimed to evaluate the usability, that is, feasibility and acceptability, as well as effectiveness of mHealth lifestyle and medical apps to support health care during pregnancy in high-income countries...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29690917/health-consequences-for-mother-and-baby-of-substantial-pre-conception-weight-loss-in-obese-women-study-protocol-for-a-randomized-controlled-trial
#3
Sarah Price, Alison Nankervis, Michael Permezel, Luke Prendergast, Priya Sumithran, Joseph Proietto
BACKGROUND: Current guidelines for the management of obesity in women planning pregnancy suggest lifestyle modification before conception. However, there is little evidence that lifestyle modification alters pregnancy outcomes. Bariatric surgery results in significant weight loss. This appears to reduce the risk of adverse pregnancy outcomes for the mother but may increase the risk of adverse outcomes for the infant. In order to reduce the risks of obesity-related adverse pregnancy outcomes for both mother and offspring, alternative approaches to the management of obesity in women planning pregnancy are needed...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29689749/the-association-between-alcohol-outlet-accessibility-and-adverse-birth-outcomes-a-retrospective-cohort-study
#4
J A Seabrook, N Woods, A Clark, B de Vrijer, D Penava, J Gilliland
BACKGROUND: Alcohol outlet accessibility is positively associated with alcohol consumption, although this relationship has not been thoroughly examined in pregnant women. The present study examines the relationship between proximity and density of alcohol outlets and risk for low birth weight (LBW: <2,500 grams) and preterm birth (PTB: <37 weeks gestational age), and is the first Canadian study to investigate this association. METHODS: Maternal accessibility to alcohol outlets was specified using a gravity-type measure of accessibility, which provides the amount of accessibility that a given household has to liquor stores within 30-minutes of their home...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29689321/gestational-weight-gain-and-weight-loss-among-women-with-gestational-diabetes-mellitus
#5
Daphna Komem, Lina Salman, Eyal Krispin, Nissim Arbib, Ron Bardin, Arnon Wiznitzer, Eran Hadar
AIMS: To assess the association of gestational weight gain or loss with adverse pregnancy outcome among women with gestational diabetes mellitus (GDM). METHODS: Retrospective study of all women diagnosed with GDM, from July 2012 to December 2016, stratified by gestational weight change according to the institute of medicine recommendations. Primary maternal outcome was glycemic control and primary neonatal outcome was large or small for gestational age (LGA or SGA)...
April 21, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29689109/maternal-vitamin-d-deficiency-increases-the-risk-of-adverse-neonatal-outcomes-in-the-chinese-population-a-prospective-cohort-study
#6
Yuanliu Wang, Honghui Li, Min Zheng, Yubi Wu, Ting Zeng, Jinjian Fu, Dingyuan Zeng
BACKGROUND: Although vitamin D (vitD) deficiency is a common problem in pregnant women, in China, few studies have focused on the relationship between maternal vitD deficiency throughout the three trimesters and subsequent neonatal outcomes in China. METHODS: Between 2015 and 2016, maternal serum and neonate cord blood samples were collected from 1978 mother-neonate pairs from Liuzhou city. RESULTS: The mean concentrations of 25-hydroxy vitD (25(OH)D) were 16...
2018: PloS One
https://www.readbyqxmd.com/read/29688261/prenatal-exposure-to-acetaminophen-and-risk-for-attention-deficit-hyperactivity-disorder-and-autistic-spectrum-disorder-a-systematic-review-meta-analysis-and-meta-regression-analysis-of-cohort-studies
#7
Reem Masarwa, Hagai Levine, Einat Gorelik, Shimon Reif, Amichai Perlman, Ilan Matok
Acetaminophen is the most commonly used analgesic and antipyretic during pregnancy. Evidence of neuro-disruptive properties is accumulating. Therefore, we sought to evaluate the risk for attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD) in the offspring of women exposed to acetaminophen during pregnancy. We searched MEDLINE, EMBASE, and Cochrane up to January 2017. Data were independently extracted and assessed by two researchers. Seven eligible retrospective cohorts included 132,738 mother and child pairs and with a follow-up period of 3-11 years...
April 24, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29688184/-psychotropic-drugs-in-pregnancy
#8
Zsuzsa Valasinyovszki, Alexander Kancsev
According to the statistics, there is an increased number of pregnant women taking psychotropic medication. For each clinical decision, or change in therapy that affect women of reproductive age, one has to consider the available information on the reproductive safety of psychiatric drugs. Due to ethical considerations, there are no randomized, double-blind, placebo-controlled studies, hence no unequivocal evidence addressing this topic. When used during pregnancy, there might be potential adverse effects of psychotropic drugs in regards to the following: teratogenicity, pregnancy outcome, obstetrical complications, neonatal toxicity and withdrawal syndrome, breastfeeding, and the offspring's long-term intellectual, behavioral, emotional development...
2018: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/29687743/clinical-outcomes-of-treatment-with-filgrastim-versus-a-filgrastim-biosimilar-and-febrile-neutropenia-associated-costs-among-patients-with-nonmyeloid-cancer-undergoing-chemotherapy
#9
Lee S Schwartzberg, Lincy S Lal, Sanjeev Balu, Kim Campbell, Lee Brekke, Andrew DeLeon, Caitlin Elliott, Stephanie Korrer
BACKGROUND: Granulocyte colony-stimulating factors such as filgrastim are used to decrease the incidence of febrile neutropenia (FN) among patients with nonmyeloid cancers undergoing chemotherapy treatment. Although the biosimilar filgrastim-sndz has been approved in the United States since 2015, limited real-world comparisons of filgrastim-sndz versus reference filgrastim (filgrastim-ref) have been conducted. OBJECTIVE: To compare FN incidence and assess overall FN-related health care resource utilization and medical costs among U...
April 24, 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29686956/management-of-primary-mediastinal-b-cell-lymphoma-in-pregnancy
#10
Sidra Khalid, Aariez Khalid, Hamed Daw, Praful Maroo
Primary mediastinal B-cell lymphoma (PMBCL) is a subtype of non-Hodgkin's lymphoma, which occurs rarely in pregnancy. We present a case of a pregnant 22-year-old female who presented with syncope and dyspnea. Computed tomography (CT) chest showed an anterior mediastinal mass, and its biopsy showed PMBCL. Since she was in her second trimester, we decided to treat her with rituximab-cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP). Our case emphasizes the safety of chemotherapy in the second and third trimesters, with good maternal and fetal outcomes...
February 21, 2018: Curēus
https://www.readbyqxmd.com/read/29686936/complete-placenta-previa-ultrasound-biometry-and-surgical-outcomes
#11
Alison C Wortman, Stephanie L Schaefer, Donald D McIntire, Jeanne S Sheffield, Diane M Twickler
Objective  To evaluate the relationship between surgical outcomes and ultrasound measurement of placental extension beyond the cervical os in women with placenta previa. Study Design  This is a retrospective cohort study of singleton pregnancies with placenta previa undergoing third-trimester ultrasound and delivering at our institution from 2002 through 2011. For study purposes, an investigator measured placental extension, defined as the placental distance from the internal os across the placenta continuing out to the lowest placental edge...
April 2018: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29686009/influence-of-gestational-age-at-initiation-of-antihypertensive-therapy-secondary-analysis-of-chips-trial-data-control-of-hypertension-in-pregnancy-study
#12
Anouk Pels, Ben Willem J Mol, Joel Singer, Terry Lee, Peter von Dadelszen, Wessel Ganzevoort, Elizabeth Asztalos, Laura A Magee
For hypertensive women in CHIPS (Control of Hypertension in Pregnancy Study), we assessed whether the maternal benefits of tight control could be achieved, while minimizing any potentially negative effect on fetal growth, by delaying initiation of antihypertensive therapy until later in pregnancy. For the 981 women with nonsevere, chronic or gestational hypertension randomized to less-tight (target diastolic blood pressure, 100 mm Hg), or tight (target, 85 mm Hg) control, we used mixed-effects logistic regression to examine whether the effect of less-tight (versus tight) control on major outcomes was dependent on gestational age at randomization, adjusting for baseline factors as in the primary analysis and including an interaction term between gestational age at randomization and treatment allocation...
April 23, 2018: Hypertension
https://www.readbyqxmd.com/read/29685731/gestational-diabetes-mellitus-glycemic-control-during-pregnancy-and-neonatal-outcomes-of-twin-and-singleton-pregnancies
#13
María Augusta Guillén-Sacoto, Beatriz Barquiel, Natalia Hillman, María Ángeles Burgos, Lucrecia Herranz
OBJECTIVE: To assess the impact of glycemic control in gestational on neonatal weight and metabolic complications of twin and singleton pregnancies. METHODS: An observational, retrospective study to monitor 120 twin and 240 singleton pregnancies in women with GDM. Maternal glycemic parameters during pregnancy (oral glucose tolerance test results, treatment, insulinization rate, mean HbA1c in the third trimester), and neonatal complications and weight were recorded...
April 20, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29685714/dilated-cardiomyopathy-in-pregnancy-outcomes-from-an-australian-tertiary-centre-for-maternal-medicine-and-review-of-the-current-literature
#14
Siobhan Boyle, Mugur Nicolae, Karam Kostner, Kathy Davies, Irena Cukovski, Amanda Cunliffe, Adam Morton
BACKGROUND: Peripartum cardiomyopathy is associated with significant risks of decline in left ventricular function and adverse maternal and fetal outcome in subsequent pregnancy. The risks of pregnancy in women with dilated cardiomyopathy are unclear. We aimed to assess the outcome of pregnancy in women with dilated cardiomyopathy seen at our institution and to review the literature on this subject. METHODS: A retrospective audit of the outcomes of 14 pregnancies to 12 women with dilated cardiomyopathy...
March 2, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29685179/prophylactic-antibiotics-to-reduce-pelvic-infection-in-women-having-miscarriage-surgery-the-aims-antibiotics-in-miscarriage-surgery-trial-study-protocol-for-a-randomized-controlled-trial
#15
David Lissauer, Amie Wilson, Jane Daniels, Lee Middleton, Jon Bishop, Catherine Hewitt, Abi Merriel, Andrew Weeks, Chisale Mhango, Ronald Mataya, Frank Taulo, Theresa Ngalawesa, Agatha Chirwa, Colleta Mphasa, Tayamika Tambala, Grace Chiudzu, Caroline Mwalwanda, Agnes Mboma, Rahat Qureshi, Iffat Ahmed, Humera Ismail, Metin Gulmezoglu, Olufemi T Oladapo, Godfrey Mbaruku, Jerome Chibwana, Grace Watts, Beatus Simon, James Ditai, Charles Otim Tom, Jane-Frances Acam, John Ekunait, Helen Uniza, Margaret Iyaku, Margaret Anyango, Javier Zamora, Tracy Roberts, Ilias Goranitis, Nicola Desmond, Arri Coomarasamy
BACKGROUND: The estimated annual global burden of miscarriage is 33 million out of 210 million pregnancies. Many women undergoing miscarriage have surgery to remove pregnancy tissues, resulting in miscarriage surgery being one of the most common operations performed in hospitals in low-income countries. Infection is a serious consequence and can result in serious illness and death. In low-income settings, the infection rate following miscarriage surgery has been reported to be high. Good quality evidence on the use of prophylactic antibiotics for surgical miscarriage management is not available...
April 23, 2018: Trials
https://www.readbyqxmd.com/read/29685129/factors-associated-with-caesarean-deliveries-among-child-bearing-women-in-pakistan-secondary-analysis-of-data-from-the-demographic-and-health-survey-2012-13
#16
Aaisha Amjad, Uzair Amjad, Rubeena Zakar, Ahmed Usman, Muhammad Zakria Zakar, Florian Fischer
BACKGROUND: The increasing rate of caesarean deliveries has become a serious concern for public health experts globally. Various medical and non-medical factors, such as maternal socio-demographics, are found to be responsible for this upsurge. Like in other countries, the rate of caesarean sections has increased in Pakistan as well. Therefore, there is a need to investigate the factors behind this increase. This study aims to assess the determinants associated with caesarean deliveries among child-bearing women aged 15-49 years in Pakistan...
April 23, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29685127/validation-of-a-self-administered-web-based-24-hour-dietary-recall-among-pregnant-women
#17
Claudia Savard, Simone Lemieux, Jacynthe Lafrenière, Catherine Laramée, Julie Robitaille, Anne-Sophie Morisset
BACKGROUND: The use of valid dietary assessment methods is crucial to analyse adherence to dietary recommendations among pregnant women. This study aims to assess the relative validity of a self-administered Web-based 24-h dietary recall, the R24W, against a pen-paper 3-day food record (FR) among pregnant women. METHODS: Sixty (60) pregnant women recruited at 9.3 ± 0.7 weeks of pregnancy in Quebec City completed, at each trimester, 3 R24W and a 3-day FR. Mean energy and nutrient intakes reported by both tools were compared using paired Student T-Tests...
April 23, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29685119/prevalence-risk-factors-and-associated-adverse-pregnancy-outcomes-of-anaemia-in-chinese-pregnant-women-a-multicentre-retrospective-study
#18
Li Lin, Yumei Wei, Weiwei Zhu, Chen Wang, Rina Su, Hui Feng, Huixia Yang
BACKGROUND: Anaemia in pregnant women is a public health problem, especially in developing countries. The aim of this study was to assess the prevalence and related risk factors of anaemia during pregnancy in a large multicentre retrospective study (n = 44,002) and to determine the adverse pregnancy outcomes in women with or without anaemia. METHODS: The study is a secondary data analysis of a retrospective study named "Gestational diabetes mellitus Prevalence Survey (GPS) study in China"...
April 23, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29685081/longitudinal-trajectory-of-vulvovaginal-candidiasis-trichomoniasis-and-bacterial-vaginosis-during-pregnancy-as-well-as-the-impact-on-pregnancy-outcome-a-preliminary-study
#19
Cheng-Yang Hu, Feng-Li Li, Xiao-Guo Hua, Wen-Jiang, Xiu-Jun Zhang
OBJECTIVES: The aims of this study were to describe the course of vulvovaginal candidiasis (VVC), trichomoniasis, and bacterial vaginosis (BV) in pregnancy and to explore the association between these longitudinal changes and pregnancy outcomes. METHODS: A total of 793 pregnant women were enrolled at the first trimester of pregnancy and were followed prospectively twice at the second and third trimester. VVC, trichomoniasis, and BV were evaluated at each trimester of pregnancy...
April 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29685073/the-association-of-second-trimester-biomarkers-in-amniotic-fluid-and-fetal-outcome
#20
Irene Sterpu, Peter Anfelter, Susan Wray, Helena Kaihola, Helena Åkerud, Eva Wiberg-Itzel
OBJECTIVE: To identify the level of amniotic fluid lactate (AFL), placental growth factor (PLGF) and vascular endothelial growth factor (VEGF) at second trimester amniocentesis, and to compare levels in normal pregnancies with pregnancies ending in a miscarriage, an intrauterine growth restricted fetus (IUGR) or decreased fetal movements. STUDY DESIGN: A prospective cohort study. Amniotic fluid was consecutive collected at amniocentesis in 106 pregnancies. Fetal wellbeing at delivery was evaluated from medical files and compared with the levels of AFL, VEGF and PLGF at the time of amniocentesis...
April 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
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