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https://www.readbyqxmd.com/read/29244733/the-association-of-triiodothyronine-to-thyroxine-ratio-with-body-mass-index-in-obese-nigerian-children-and-adolescents
#1
Mathias Abiodun Emokpae, Progress Arhenrhen Obazelu
The interest in the relationship between thyroid dysfunction and obesity is on the increase. This study compares the triiodothyronine-to-thyroxine (T3/T4) ratio in obese and lean children and adolescents, and correlates thyroid hormones with body mass index (BMI) in obese Nigerian children. It is a retrospective study of records of 76 obese children and adolescents with a BMI of 31.7 ± 0.1 kg/m² (26 males aged 10.9 ± 0.35 years, and 50 females aged 10.8 ± 0.4 years) that were referred to the laboratory for thyroid hormone evaluation because of their obese status...
December 15, 2017: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29243589/defective-stim-mediated-store-operated-ca2-entry-in-hepatocytes-leads-to-metabolic-dysfunction-in-obesity
#2
Ana Paula Arruda, Benedicte Mengel Pers, Günes Parlakgul, Ekin Güney, Ted Goh, Erika Cagampan, Grace Yankun Lee, Renata L Goncalves, Gökhan S Hotamisligil
Defective Ca2+ handling is a key mechanism underlying hepatic endoplasmic reticulum (ER) dysfunction in obesity. ER Ca2+ level is in part monitored by the store-operated Ca2+ entry (SOCE) system, an adaptive mechanism that senses ER luminal Ca2+ concentrations through the STIM proteins and facilitates import of the ion from the extracellular space. Here, we show that hepatocytes from obese mice displayed significantly diminished SOCE as a result of impaired STIM1 translocation, which was associated with aberrant STIM1 O-GlycNAcylation...
December 15, 2017: ELife
https://www.readbyqxmd.com/read/29243375/parental-experiences-and-perceptions-of-infant-complementary-feeding-a-qualitative-evidence-synthesis
#3
REVIEW
K Matvienko-Sikar, C Kelly, C Sinnott, J McSharry, C Houghton, C Heary, E Toomey, M Byrne, P M Kearney
BACKGROUND: Interventions to prevent childhood obesity increasingly focus on infant feeding, but demonstrate inconsistent effects. A comprehensive qualitative evidence synthesis is essential to better understand feeding behaviours and inform intervention development. The aim of this study is to synthesize evidence on perceptions and experiences of infant feeding and complementary feeding recommendations. METHODS: Databases CINAHL, EMBASE, MEDLINE, PsycINFO, Academic Search Complete, SocIndex and Maternity and Infant Care were searched from inception to May 2017...
December 15, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29242844/effects-of-increased-body-weight-and-short-term-weight-loss-on-serum-pcsk9-levels-a-prospective-pilot-study
#4
Theodosios D Filippatos, Evangelos Liberopoulos, Maria Georgoula, Constantinos C Tellis, Alexandros D Tselepis, Moses Elisaf
Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with low-density lipoprotein (LDL) catabolism, but its serum concentration is not uniformly associated with cardiovascular disease in clinical studies. Obesity is linked with increased cardiovascular risk, but the effect of increased body weight and short-term weight loss on serum PCSK9 levels is not well studied. Material and methods: The aim of this prospective pilot study was to assess differences in serum PCSK9 levels (determined with a quantitative sandwich enzyme immunoassay) between otherwise healthy drug-naïve obese subjects and healthy individuals with normal body weight...
2017: Archives of Medical Sciences. Atherosclerotic Diseases
https://www.readbyqxmd.com/read/29242817/vitamin-d-deficiency-and-association-with-body-mass-index-and-lipid-levels-in-hispanic-american-adolescents
#5
Mohan Kumaratne, Gayle Early, Jasmine Cisneros
In this retrospective study, vitamin D deficiency was examined with body mass index (BMI) and lipid levels in a sample of Hispanic American adolescents. The prevalence of vitamin D deficiency among 234 subjects aged 13 to 19 years was 27.8%. Vitamin D deficiency was significantly associated with a BMI of 85 kg/m2 or higher (odds ratio = 2.02, 95% confidence interval = 1.11-3.69, χ2 = 5.37, P = .021), and 55.6% of the sample were overweight or obese (BMI ≥ 85%). In the overweight or obese subjects, vitamin D deficiency was significantly associated with higher mean lipid levels compared with those with adequate vitamin D levels: total cholesterol = 165 ± 28...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29242739/healthy-food-availability-among-food-sources-in-rural-maryland-counties
#6
Elizabeth A Campbell, Myra J Shapiro, Claire Welsh, Sara N Bleich, Laura K Cobb, Joel Gittelsohn
Most studies examining the association of the food environment and health outcomes have focused on urban settings. However, rural adults and children have high rates of obesity, which may be related to their food environments. This study examines the food environment in 7 rural counties in Maryland. A cross-sectional study was conducted at 244 retail food stores from 2012 to 2013. Data on store-level characteristics were collected and a healthy food availability index (HFAI) ranging from 0 to 31 points was calculated for each store...
2017: Journal of Hunger & Environmental Nutrition
https://www.readbyqxmd.com/read/29242640/effects-of-maternal-obesity-on-wharton-s-jelly-mesenchymal-stromal-cells
#7
Heba Badraiq, Aleksandra Cvoro, Antonio Galleu, Marisa Simon, Cristian Miere, Carl Hobbs, Reiner Schulz, Richard Siow, Francesco Dazzi, Dusko Ilic
We investigated whether maternal metabolic environment affects mesenchymal stromal/stem cells (MSCs) from umbilical cord's Wharton's Jelly (WJ) on a molecular level, and potentially render them unsuitable for clinical use in multiple recipients. In this pilot study on umbilical cords post partum from healthy non-obese (BMI = 19-25; n = 7) and obese (BMI ≥ 30; n = 7) donors undergoing elective Cesarean section, we found that WJ MSC from obese donors showed slower population doubling and a stronger immunosuppressive activity...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29242527/correlates-of-overall-and-central-obesity-in-adults-from-seven-european-countries-findings-from-the-food4me-study
#8
Carlos Celis-Morales, Katherine M Livingstone, Alexander Affleck, Santiago Navas-Carretero, Rodrigo San-Cristobal, J Alfredo Martinez, Cyril F M Marsaux, Wim H M Saris, Clare B O'Donovan, Hannah Forster, Clara Woolhead, Eileen R Gibney, Marianne C Walsh, Lorraine Brennan, Mike Gibney, George Moschonis, Christina-Paulina Lambrinou, Christina Mavrogianni, Yannis Manios, Anna L Macready, Rosalind Fallaize, Julie A Lovegrove, Silvia Kolossa, Hannelore Daniel, Iwona Traczyk, Christian A Drevon, John C Mathers
BACKGROUND/OBJECTIVES: To identify predictors of obesity in adults and investigate to what extent these predictors are independent of other major confounding factors. SUBJECTS/METHODS: Data collected at baseline from 1441 participants from the Food4Me study conducted in seven European countries were included in this study. A food frequency questionnaire was used to measure dietary intake. Accelerometers were used to assess physical activity levels (PA), whereas participants self-reported their body weight, height and waist circumference via the internet...
December 15, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29241364/health-benefits-of-pistachios-consumption
#9
Simona Terzo, Sara Baldassano, Gaetano Felice Caldara, Vincenzo Ferrantelli, Gianluigi Lo Dico, Flavia Mulè, Antonella Amato
The health benefits of nuts, mainly in relation to the improvement of dysmetabolic conditions such as obesity, type 2 diabetes mellitus and the related cardiovascular diseases, have been widely demonstrated. Compared to other nuts, pistachios have a lower fat and caloric content, and contain the highest levels of unsaturated fatty acids, potassium, γ-tocopherol, phytosterols and xanthophyll carotenoids, all substances that are well known for their antioxidant and anti-inflammatory actions. This variety of nutrients contributes to the growing body of evidence that the consumption of pistachios improves health, leading to a greater potential of healthy antioxidant and anti-inflammatory activity, glycemic control, and endothelial function...
December 15, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29240836/is-quality-of-life-different-between-diabetic-and-non-diabetic-people-the-importance-of-cardiovascular-risks
#10
L M Peña-Longobardo, B Rodríguez-Sánchez, M Mata-Cases, L Rodríguez-Mañas, M Capel, J Oliva-Moreno
BACKGROUND: To analyse and compare the impact of cardiovascular risk factors and disease on health-related quality of life (HRQoL) in people with and without diabetes living in the community. METHODS: We used data of 1,905 people with diabetes and 19,031 people without diabetes from the last Spanish National Health Survey (years 2011-2012). The HRQoL instrument used was the EuroQol 5D-5L, based on time trade-off scores. Matching methods were used to assess any differences in the HRQoL in people with and without diabetes with the same characteristics (age, gender, education level, and healthy lifestyle), according to cardiovascular risk factors and diseases...
2017: PloS One
https://www.readbyqxmd.com/read/29240304/weight-status-diet-quality-perceived-stress-and-functional-health-of-caregivers-of-children-with-autism-spectrum-disorder
#11
Xiaoyin Sara Li, Jennifer A Pinto-Martin, Aleda Thompson, Jesse Chittams, Tanja V E Kral
PURPOSE: Caring for children with autism spectrum disorder (ASD) can be highly demanding and can put significant strain on caregivers. To date, little is known about the extent to which caregivers of children with ASD experience increased levels of stress which may adversely affect health outcomes. The purpose of this secondary analysis was to compare caregivers of children with ASD and caregivers of typically developing children (TDC) in weight status, diet quality, perceived stress related to the parenting role, and functional health and well-being...
December 14, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29239056/association-of-body-mass-index-and-weight-gain-patterns-with-albumin-excretion-in-pregnancy
#12
Özlem B Tulmaç, Zeynep Ö Dağ, Funda Erdoğan, Cemile D Sayan, Nevin Sağsöz
AIM: We examined body mass index (BMI) and gestational weight gain (GWG) patterns of pregnant women and investigated the impact of these factors on the urinary albumin-creatinine ratio (ACR) during pregnancy. METHODS: The data of 163 women whose basal BMI and ACR were measured during the first trimester were used in this study. Body weight alone between 12-16 weeks and body weight together with ACR after 37 weeks of gestation were measured. RESULTS: Overall, 46% of women were overweight or obese, 60...
December 14, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29238916/impact-of-bariatric-surgical-intervention-on-peripheral-blood-neutrophil-pbn-function-in-obesity
#13
Helen M Roberts, Melissa M Grant, Naomi Hubber, Paul Super, Rishi Singhal, Iain L C Chapple
AIM: The aim of this study was to investigate the impact of weight loss following gastric band surgery on multiple measures of peripheral blood neutrophil (PBN) function. MATERIAL AND METHODS: Twenty-three obese patients undergoing gastric band surgery were recruited to a longitudinal intervention study, alongside non-obese, healthy gender- and age-matched controls. Eighteen pairs of patients and controls completed all stages of the study. PBNs were isolated by density centrifugation and a comprehensive analysis of PBN function was undertaken at various stages of the patients' bariatric surgical care pathway...
December 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29238351/natural-killer-cell-activity-and-interleukin-12-in-metabolically-healthy-versus-metabolically-unhealthy-overweight-individuals
#14
Minjoo Kim, Minkyung Kim, Hye Jin Yoo, Jong Ho Lee
The purpose of this study was to determine whether the immune system is involved in the different metabolic circumstances in healthy and unhealthy overweight individuals. We examined the metabolic and immune characteristics of 117 overweight individuals. Subjects were classified as metabolically healthy overweight (MHO, n = 72) or metabolically unhealthy overweight (MUO, n = 45). The immune response was measured by circulating levels of natural killer (NK) cell activity and cytokines. Both groups were comparable with regards to age, sex distribution, smoking and drinking status, and body mass index...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29238170/adherence-to-treatment-and-evaluation-of-disease-and-therapy-knowledge-in-lebanese-hypertensive-patients
#15
Hanine Abbas, Mazen Kurdi, Myriam Watfa, Rita Karam
Background: Adherence to treatment, healthy lifestyle, physical activities, smoking, diet, and salt intake are important factors to control for an effective decrease in blood pressure (BP) values for patients diagnosed with essential hypertension (HT). The aim of this work was to study the adherence to antihypertensive treatment and factors predicting this behavior in Lebanese patients. In addition, we evaluated the extent of patient's knowledge and perceptions about HT, risk factors, and medication side effects...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29237763/bisphenol-a-phthalate-metabolites-and-glucose-homeostasis-in-healthy-normal-weight-children
#16
Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen, Anders Juul
INTRODUCTION: Bisphenol A and several of the most commonly used phthalates have been associated with adverse metabolic health effects such as obesity and diabetes. Therefore, we analyzed these man-made chemicals in first morning urine samples from 107 healthy normal-weight Danish children and adolescents. METHOD: This was a cross-sectional study. Participants were recruited as part of The COPENHAGEN Puberty Study. The subjects were evaluated by an oral glucose tolerance test (OGTT), a dualenergy X-ray absorptiometry (DXA) scan, direct oxygen uptake measurement during cycle ergometry, and fasting blood samples...
December 13, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29237522/-an-analysis-of-cardiac-autonomic-nerve-function-in-girls-with-idiopathic-central-precocious-puberty
#17
Lan-Fen Yi, Hong-Xia Wen, Mei Qiu, Xiao-Xiao Cao
OBJECTIVE: To investigate the cardiac autonomic nerve function in girls with idiopathic central precocious puberty (ICPP). METHODS: A total of 66 girls with ICPP were enrolled, among whom 36 were obese and 30 were not obese. A total of 68 age-matched healthy girls (normal controls) and 51 girls with simple obesity were enrolled as controls. All the subjects underwent 24-hour ambulatory electrocardiography, and deceleration capacity of heart rate (DC), acceleration capacity of heart rate (AC), and heart rate variability (HRV), and body mass index (BMI) were compared between groups...
December 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29237437/the-impact-of-a-community-led-program-promoting-weight-loss-and-healthy-living-in-aboriginal-communities-the-new-south-wales-knockout-health-challenge
#18
Erin Passmore, Brooke Shepherd, Andrew Milat, Louise Maher, Kiel Hennessey, Rachael Havrlant, Michelle Maxwell, Wendy Hodge, Fiona Christian, Justin Richards, Jo Mitchell
BACKGROUND: Aboriginal people in Australia experience significant health burden from chronic disease. There has been limited research to identify effective healthy lifestyle programs to address risk factors for chronic disease among Aboriginal people. METHODS: The Knockout Health Challenge is a community-led healthy lifestyle program for Aboriginal communities across New South Wales, Australia. An evaluation of the 2013 Knockout Health Challenge was undertaken. Participants' self-reported physical activity and diet were measured at four time points - at the start and end of the Challenge (via paper form), and 5 and 9 months after the Challenge (via telephone survey)...
December 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29237186/-current-literature-overview-on-the-therapy-of-obesity-in-children-and-adolescents
#19
Jana Brauchmann, Susann Weihrauch-Blüher, Stefan Ehehalt, Susanna Wiegand
Background Obesity is a chronic disease due to the comorbidity associated with it and the need for long-term medical care. Therapeutic intervention is possible at every stage of pathophysiology. Aim The aim of the study is to demonstrate the effect of multimodal lifestyle interventions not only on the BMI/BMI-SDS, but also on (secondary) outcomes such as comorbidities, quality of life as well as the nutritional and movement behavior. Materials and Methods The literature database PubMed has been searched for internationally clinical studies on lifestyle interventions among 0 to 18-year-olds with overweight and obesity in the period from 01/01/2009 to 01/01/2016...
December 13, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29237159/sugar-sweetened-beverages-and-weight-gain-in-children-and-adults-a-systematic-review-from-2013-to-2015-and-a-comparison-with-previous-studies
#20
Maria Luger, Max Lafontan, Maira Bes-Rastrollo, Eva Winzer, Volkan Yumuk, Nathalie Farpour-Lambert
OBJECTIVE: Partly inconsistent findings from previous reviews have fueled discussions on the impact of sugar-sweetened beverages (SSBs) on obesity development. The aim was to systematically review the recent evidence in children and adults. METHODS: Data were retrieved from the databases MEDLINE, EMBASE, and Cochrane library for the period January 2013 to October 2015. A systematic review of prospective cohort studies and randomized controlled trials (RCTs) relating SSBs to weight measures was conducted...
December 14, 2017: Obesity Facts
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