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https://www.readbyqxmd.com/read/28803700/association-of-androgen-deprivation-therapy-and-depression-in-the-treatment-of-prostate-cancer-a-systematic-review-and-meta-analysis
#1
Kevin T Nead, Sumi Sinha, David D Yang, Paul L Nguyen
BACKGROUND: There is increasing evidence that androgen deprivation therapy (ADT) may be associated with depression. Existing studies have shown conflicting results. METHODS: PubMed, Web of Science, Embase, and PsycINFO were queried on April 5, 2017. Eligible studies were in English and reported depression among individuals with prostate cancer exposed to a course of ADT vs. a lesser-exposed group (e.g., any-ADT vs. no ADT and continuous ADT vs. intermittent ADT)...
August 10, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28802297/breastfeeding-and-early-childhood-caries-a-meta-analysis-of-observational-studies
#2
Lingling Cui, Xing Li, Yalan Tian, Juntao Bao, Ling Wang, Dongmei Xu, Bing Zhao, Wenjie Li
BACKGROUND AND OBJECTIVES: The associations of breastfeeding and early childhood caries (ECC) risk have been evaluated in several epidemiological studies with conflicting results. We performed an update meta-analysis to estimate the association of feeding patterns, breastfeeding durations and ECC risk. METHODS AND STUDY DESIGN: Studies were identified through searching Pubmed, Web of Science, and Embase from January 1990 to December 2015. RESULTS: Thirty-five studies involving 73,401 participants aged 0-71 months were included...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28797987/continued-use-of-low-dose-aspirin-may-increase-risk-of-bleeding-after-gastrointestinal-endoscopic-submucosal-dissection-a-meta-analysis
#3
Wei Wu, Jingdi Chen, Qianshan Ding, Dongmei Yang, Honggang Yu, Jun Lin
BACKGROUND/AIMS: Endoscopic submucosal dissection has been widely accepted. At present, the number of antiplatelet (APT) users has been growing. Moreover, because of high risks of thromboembolism, some patients need to continuously receive APT agents. The relationship between hemorrhage and continuous therapy with low-dose aspirin (LDA) remains controversial. MATERIALS AND METHODS: A systematic search was conducted; studies were screened out- if data of no-anticoagulant/APT drugs use and interrupted and continued-LDA use were reported separately...
August 9, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28797573/digestive-decontamination-in-burn-patients-a-systematic-review-of-randomized-clinical-trials-and-observational-studies
#4
REVIEW
Mercedes Rubio-Regidor, Ana Martín-Pellicer, Luciano Silvestri, Hendrik K F van Saene, José A Lorente, Miguel A de la Cal
OBJECTIVE: The objective of this systematic review is to assess the effect of selective digestive decontamination (SDD) or non-absorbable enteral antibiotics (EA) on mortality, the incidence of infection and its adverse effects in burn patients. MATERIAL AND METHODS: Systematic review of randomized clinical trials (RCT) or observational studies enrolling burn patients, and comparing SDD or EA prophylaxis with placebo or no treatment. The search includes Pubmed/Medline, EMBASE, WOS, Cochrane Library (1970-2015)...
August 7, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28790846/the-association-between-spink1-and-clinical-outcomes-in-patients-with-prostate-cancer-a-systematic-review-and-meta-analysis
#5
Xingming Zhang, Xiaoxue Yin, Pengfei Shen, Guangxi Sun, Yaojing Yang, Jiandong Liu, Ni Chen, Hao Zeng
Evidence of the prognostic role of serine peptidase inhibitor Kazal type 1 (SPINK1) in prostate cancer (PCa) is controversial. The aim of this study was, therefore, to evaluate the association between SPINK1 and clinical outcomes in PCa. Searches were made of PubMed, Medline, Embase, and the China Biology Medicine disc (CBMdisc) up to January 2017. The Newcastle-Ottawa Scale was used to assess the risk of bias of included studies. RevMan software was used to perform meta-analysis, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method was employed for assessing the quality of the evidence...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28783371/molecular-characterization-and-biological-activity-of-interferon-%C3%AE-in-indian-peafowl-pavo-cristatus
#6
Hongjing Zhao, Yu Wang, Juanjuan Liu, Yizhi Shao, Jinglun Li, Hongliang Chai, Mingwei Xing
Interferon-α (IFN-α) genes have been cloned from a variety of animals, but information about Indian peafowl Pavo cristatus IFN-α (PcIFN-α) has not been reported. In this study, a PcIFN-α gene was amplified, which encoded a protein of 193 amino acids with a 26-amino acid signal peptide sharing 72.16-95.70% identity with other avians in Aves. After expression in prokaryote, purification, and renaturation, PcIFN-α was analyzed for its physicochemical property and antiviral activity. Cytopathic inhibition test showed that the recombinant PcIFN-α could inhibit the replication of vesicular stomatitis virus (VSV), Newcastle disease virus (NDV), and avian influenza virus (AIV) on chicken embryo fibroblasts...
August 7, 2017: DNA and Cell Biology
https://www.readbyqxmd.com/read/28777739/statins-and-the-risk-of-cirrhosis-in-hepatitis-b-or-c-patients-a-systematic-review-and-dose-response-meta-analysis-of-observational-studies
#7
Yaqin Wang, Jianping Xiong, Meng Niu, Xiaowei Chen, Long Gao, Qirun Wu, Kechuang Zheng, Ke Xu
Hepatitis B and hepatitis C are leading causes of chronic liver disease, particularly cirrhosis. Recently, several studies have observed that statins have an inverse relationship with cirrhosis in hepatitis B or C patients. However, no published meta-analysis studied the protective effect of statins on cirrhosis. Thus, we conducted a systematic review and meta-analysis of published observational studies to better understand the relationship between statins and the risk of cirrhosis. Relevant studies were identified by searching PubMed, EMBASE, and ISI Web of Science for articles published before April 2017...
July 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28776685/patients-experiences-and-satisfaction-about-care-provided-by-male-nurses-in-medical-surgical-units-in-islamabad-pakistan-a-pilot-study
#8
Ahtisham Younas, Amara Sundus
BACKGROUND: Nursing is predominantly a female profession and caring has been considered an attribute of female nurses, which could imply a noncaring image of male nurses. AIM: To determine patients' experiences and satisfaction from care provided by male nurses in a private hospital in Islamabad, Pakistan. METHODS: This cross-sectional study included a purposive sample of 50 patients admitted to medical surgical units for at least 2 days and who had at least three professional interactions with a male nurse...
August 4, 2017: Nursing Forum
https://www.readbyqxmd.com/read/28775196/systematic-review-and-meta-analysis-of-infant-and-young-child-feeding-practices-enat-p-in-ethiopia-protocol
#9
Tesfa Dejenie Habtewold, Md Atiqul Islam, Nigussie Tadesse Sharew, Shimels Hussien Mohammed, Mulugeta Molla Birhanu, Balewgizie Sileshi Tegegne
INTRODUCTION: Infant and young child feeding (IYCF) is the cornerstone of infant and child survival, healthy growth and development, healthy future generations and national development. In spite of the importance of optimal nutrition in low- and middle-income countries, there has been no review conducted in Ethiopia. Thus, the aim of this systematic review and meta-analysis is to estimate the national coverage and identify the associated factors of IYCF practices in Ethiopia. METHODS: PubMed, Scopus, EMBASE, CINHAL, EBSCO, Web of Science and WHO Global Health Library databases will be searched for all available publications from 1 January 2000 to 30 September 2017...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28771518/cholecystectomy-can-increase-the-risk-of-colorectal-cancer-a-meta-analysis-of-10-cohort-studies
#10
Yong Zhang, Hao Liu, Li Li, Min Ai, Zheng Gong, Yong He, Yunlong Dong, Shuanglan Xu, Jun Wang, Bo Jin, Jianping Liu, Zhaowei Teng
OBJECTIVE: This study aimed to elucidate the effects of cholecystectomy on the risk of colorectal cancer (CRC) by conducting a meta-analysis of 10 cohort studies. METHODS: The eligible cohort studies were selected by searching the PubMed and EMBASE databases from their origination to June 30, 2016, as well as by consulting the reference lists of the selected articles. Two authors individually collected the data from the 10 papers. When the data showed marked heterogeneity, we used a random-effects model to estimate the overall pooled risk; otherwise, a fixed effects model was employed...
2017: PloS One
https://www.readbyqxmd.com/read/28768525/protocol-systematic-review-of-the-association-between-socio-economic-status-and-survival-in-adult-head-and-neck-cancer
#11
Bilal G Taib, Joseph Rylands, Sue Povall, Terry M Jones, David Taylor-Robinson
BACKGROUND: Head and neck cancer incidence is increasing worldwide. Despite overall improvements in survival, numerous studies suggest worse survival in more disadvantaged populations; however, this literature has not been systematically reviewed. The aim of this review is to investigate whether lower compared to higher socioeconomic status (SES) influences survival in head and neck squamous cell cancer (HNSCC) and explore possible explanations for any relationship found. METHOD: A systematic strategy will be used to identify articles, appraise their quality and extract data...
August 2, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28765919/age-at-menopause-and-hormone-replacement-therapy-as-risk-factors-for-head-and-neck-and-oesophageal-cancer%C3%A2-review
#12
Caroline E McCarthy, John K Field, Michael W Marcus
There were ~986,000 cases of head and neck cancer (HNC) and oesophageal cancer diagnosed worldwide in 2012. The incidence of these types of cancer is much higher in males than females, although this disparity decreases in the elderly population, suggesting a role for hormones as a risk factor. This systematic review investigates the potential role of female hormones [age at menopause and use of hormone replacement therapy (HRT)] as risk factors for HNC/oesophageal squamous cell carcinoma (SCC). The electronic databases MEDLINE, Web of Science, EMBASE and Cochrane were searched...
August 1, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28764757/how-accurate-is-the-surprise-question-at-identifying-patients-at-the-end-of-life-a-systematic-review-and-meta-analysis
#13
Nicola White, Nuriye Kupeli, Victoria Vickerstaff, Patrick Stone
BACKGROUND: Clinicians are inaccurate at predicting survival. The 'Surprise Question' (SQ) is a screening tool that aims to identify people nearing the end of life. Potentially, its routine use could help identify patients who might benefit from palliative care services. The objective was to assess the accuracy of the SQ by time scale, clinician, and speciality. METHODS: Searches were completed on Medline, Embase, CINAHL, AMED, Science Citation Index, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Open Grey literature (all from inception to November 2016)...
August 2, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28761647/the-association-between-diabetes-mellitus-and-incident-infections-a-systematic-review-and-meta-analysis-of-observational-studies
#14
Waseem Abu-Ashour, Laurie Twells, James Valcour, Amy Randell, Jennifer Donnan, Patricia Howse, John-Michael Gamble
OBJECTIVE: To quantify the association between diabetes and the risk of incident infections by conducting a systematic review and meta-analysis. RESEARCH DESIGN AND METHODS: Two reviewers independently screened articles identified from PubMed, EMBASE, Cochrane Library, IPA, and Web of Science databases. Cohort studies (CS) or case-control studies (CCS) evaluating the incidence of infections in adults with diabetes were included. Infections were classified as: skin and soft tissue, respiratory, blood, genitourinary, head and neck, gastrointestinal, bone, viral, and non-specified infections...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28758188/a-systematic-review-and-meta-analysis-of-the-effect-of-low-vitamin-d-on-cognition
#15
Alicia M Goodwill, Cassandra Szoeke
BACKGROUND/OBJECTIVE: With an aging population and no cure for dementia on the horizon, risk factor modification prior to disease onset is an urgent health priority. Therefore, this review examined the effect of low vitamin D status or vitamin D supplementation on cognition in midlife and older adults without a diagnosis of dementia. DESIGN: Systematic review and random effect meta-analysis. SETTING: Observational (cross-sectional and longitudinal cohort) studies comparing low and high vitamin D status and interventions comparing vitamin D supplementation with a control group were included in the review and meta-analysis...
July 31, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28756982/a-meta-analysis-of-the-relationship-between-ataxia-telangiectasia-mutated-gene-polymorphisms-and-lung-cancer-susceptibility
#16
Yanling Xu, Peng Gao, Xuejiao Lv, Lin Zhang, Wei Li, Jie Zhang
PURPOSE: This study aimed to analyze the relationship between ataxia-telangiectasia mutated (ATM) gene polymorphisms and lung cancer susceptibility using a meta-analysis. METHODS: A literature search of the PubMed and EMBASE databases was performed using keywords such as "ATM gene" and "lung cancer," and the deadline "October 15 (th), 2016." After extracting relevant details, each selected literature was evaluated for quality according to the Newcastle-Ottawa Scale (NOS) scores, and Hardy-Weinberg equilibrium and heterogeneity tests were performed...
July 6, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28756719/endograft-infection-after-endovascular-abdominal-aortic-aneurysm-repair-a-systematic-review-and-meta-analysis
#17
Christos Argyriou, George S Georgiadis, Miltos K Lazarides, Efstratios Georgakarakos, George A Antoniou
PURPOSE: To report a meta-analysis of the published evidence on the outcomes of aortic endograft infection after endovascular aneurysm repair (EVAR). METHODS: A search of electronic information sources (PubMed/MEDLINE, SCOPUS, CENTRAL) and bibliographic reference lists identified 12 studies reporting on 362 patients (mean age 72 years; 279 men). The methodological quality of the selected studies was assessed using the Newcastle-Ottawa scale. Endpoints were 30-day/in-hospital mortality and follow-up mortality...
July 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28752257/what-is-the-best-revascularization-strategy-for-acute-occlusive-arterial-mesenteric-ischemia-systematic-review-and-meta-analysis
#18
Giancarlo Salsano, Antonio Salsano, Elena Sportelli, Francesco Petrocelli, M'ahmed Dahmane, Giovanni Spinella, Bianca Pane, Simone Mambrini, Domenico Palombo, Francesco Santini
PURPOSE: Acute mesenteric ischemia (AMI) is a life-threatening disease that leads to bowel infarction and death. The optimal management of AMI remains controversial. The present meta-analysis aimed to estimate the prognostic impact of surgical (SG) versus endovascular or hybrid intervention (EV) as the first-line treatment for acute arterial occlusive mesenteric ischemia and to assess whether endovascular strategy was actually effective in reducing bowel resection. METHODS: MEDLINE, Scopus and the Cochrane Library databases were searched...
July 27, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28751035/risk-factors-of-neurosurgical-site-infection-after-craniotomy-a-systematic-review-and-meta-analysis
#19
Chenyan Fang, Tao Zhu, Ping Zhang, Liang Xia, Caixing Sun
BACKGROUND: Neurosurgical site infection (SSI) is a complication related to craniotomy, which may lead to severe morbidity and higher hospital costs during the postoperative period. METHODS: Retrospective cohorts, case-control studies, or prospective investigations addressing risk factors of SSI updated until January 2017 were systematically searched in 2 databases (PubMed and Embase). The Newcastle-Ottawa Scale was used to evaluate quality of the included studies, heterogeneity was assessed by I(2) tests, and a funnel plot and Egger test were used for the evaluation of publication bias...
July 24, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28747542/meta-analysis-showing-that-ercc1-polymorphism-is-predictive-of-osteosarcoma-prognosis
#20
REVIEW
Xueyong Liu, Zhan Zhang, Chunbo Deng, Yihao Tian, Xun Ma
To investigate correlations between excision repair cross-complementation group 1 (ERCC1) and 2 (ERCC2) polymorphisms and osteosarcoma prognosis, we conducted a meta-analysis of studies published through October 2016. Studies were identified in the PubMed, ScienceDirect, Springer, and Web of Science databases using preferred reporting items for systematic reviews and meta-analyses (PRISMA). Odds ratios (ORs) or hazard ratios (HRs) and their 95% confidence intervals (CIs) for overall survival (OS), tumor response (TR), and event-free survival (EFS) were estimated...
July 19, 2017: Oncotarget
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