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https://www.readbyqxmd.com/read/28437156/development-of-a-taqman-based-real-time-pcr-assay-for-rapid-and-specific-detection-of-fowl-aviadenovirus-serotype-4
#1
Jianchang Wang, Jinfeng Wang, Ping Chen, Libing Liu, Wanzhe Yuan
Twelve serotypes of fowl aviadenovirus, namely, FAdV-(1-8a and 8b-11), have been identified, among which FAdV-4 is the aetiologic agent of hepatitis hydropericardium syndrome (HHS) in chickens. Outbreaks of HHS have been documented in many countries, causing significant economic losses. Real-time PCR methods described so far in the literature cross-detect different serotypes of FAdVs. In this study, we aimed to develop a TaqMan-based real-time PCR assay for the specific detection of FAdV-4. A pair of primers targeting the hexon gene and a TaqMan probe were designed...
June 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28436177/limited-evidence-of-abnormal-intra-colonic-pressure-profiles-in-diverticular-disease-a-systematic-review
#2
REVIEW
R Jaung, J Robertson, G O'Grady, T Milne, D Rowbotham, I P Bissett
AIM: Abnormal colonic pressure profiles and high intraluminal pressures are postulated to contribute to the formation of sigmoid colon diverticulosis and the pathophysiology of diverticular disease (DD). This study aimed to review evidence for abnormal colonic pressure profiles in diverticulosis. METHOD: All published studies investigating colonic pressure in patients with diverticulosis were searched in three databases (MEDLINE, EMBASE, SCOPUS). No language restrictions were applied...
April 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28435194/molecular-characterization-of-velogenic-viscerotropic-ranikhet-newcastle-disease-virus-from-different-outbreaks-in-desi-chickens
#3
V S Dhaygude, G K Sawale, M M Chawak, N R Bulbule, S D Moregaonkar, D S Gavhane
AIM: Diagnosis of velogenic viscerotropic Ranikhet disease from six different flocks of desi chicken in and around Mumbai by gross and histopathological examination, isolation of virus and molecular methods. MATERIALS AND METHODS: A total of 25 carcasses (varying between 2 and 6 carcasses from each flock) of six different flocks of adult desi chicken were subjected to necropsy examination for diagnosis of the disease during the span of a year (2014-2015). After thorough gross examination, the tissue samples were collected and processed for virus isolation and histopathological examination...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28434961/cranioplasty-infection-and-resorption-are-associated-with-presence-of-a-ventriculoperitoneal-shunt-a-systematic-review-and-meta-analysis
#4
REVIEW
Christian M Mustroph, James G Malcolm, Rima S Rindler, Jason K Chu, Jonathan A Grossberg, Gustavo Pradilla, Faiz U Ahmad
BACKGROUND: Following decompressive craniectomy, hydrocephalus is a common complication often requiring placement of a ventriculoperitoneal shunt (VPS). Complications in the presence of a VPS have been reported but without clear association. METHODS: PRISMA guidelines were used to perform a literature search using PubMed to identify articles that published the complication rates associated with staged or simultaneous cranioplasty and VPS. From event rates, odds ratios [OR, 95% Confidence Interval (CI)] of complications were calculated...
April 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28427389/defining-micro-epidemiology-for-malaria-elimination-systematic-review-and-meta-analysis
#5
Melanie Bannister-Tyrrell, Kristien Verdonck, Susanna Hausmann-Muela, Charlotte Gryseels, Joan Muela Ribera, Koen Peeters Grietens
BACKGROUND: Malaria risk can vary markedly between households in the same village, or between villages, but the determinants of this "micro-epidemiological" variation in malaria risk remain poorly understood. This study aimed to identify factors that explain fine-scale variation in malaria risk across settings and improve definitions and methods for malaria micro-epidemiology. METHODS: A systematic review of studies that examined risk factors for variation in malaria infection between individuals, households, clusters, hotspots, or villages in any malaria-endemic setting was conducted...
April 20, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28427188/consumption-of-fruits-and-vegetables-and-risk-of-renal-cell-carcinoma-a-meta-analysis-of-observational-studies
#6
Shaojing Zhang, Zhankui Jia, Zechen Yan, Jinjian Yang
BACKGROUND: There have been inconsistent results about the association between consumption of fruits and vegetables and renal cell carcinoma (RCC) risk. We conducted a meta-analysis of the published observational studies to explore this association. RESULTS: Nineteen observational studies (4 cohort, 1 pooled and 14 case-control studies), involving 10,215 subjects with RCC were part of this meta-analysis. The SRR for the highest vs. the lowest intake of vegetables was 0...
March 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423596/transient-activation-of-the-pi3k-akt-pathway-promotes-newcastle-disease-virus-replication-and-enhances-anti-apoptotic-signaling-responses
#7
Yinfeng Kang, Runyu Yuan, Xiaqiong Zhao, Bin Xiang, Shimin Gao, Pei Gao, Xu Dai, Minsha Feng, Yanling Li, Peng Xie, Yulian Li, Xiaoyi Gao, Tao Ren
Viral infection activates a host's cellular phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, which is involved in cell differentiation, growth, survival, and apoptosis. To elucidate molecular mechanisms in the pathogenesis of Newcastle disease virus (NDV), we demonstrated that NDV transiently activates the PI3K/Akt pathway in chicken cells at an early phase of infection. Its activation was observed as early as 15 min post-infection and gradually weakened after 24 h. Incubating cells with a PI3K inhibitor, LY294002 or wortmannin, prior to NDV infection decreased NDV progeny yields and suppressed Akt phosphorylation at early times post-infection...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422831/association-between-diabetes-mellitus-and-subsequent-ovarian-cancer-in-women-a-systematic-review-and-meta-analysis-of-cohort-studies
#8
Lihua Wang, Liangliang Wang, Jing Zhang, Beibei Wang, Hongli Liu
Epidemiologic studies have suggested that diabetes mellitus (DM) might be associated with risk of ovarian cancer; however, the results have been inconsistent. The aim of this study was to determine the relationship between DM and the incidence of ovarian cancer on the basis of cohort studies.Relevant studies from PubMed, Embase, and the Cochrane Library until September 2016 were collected. The summary risk ratio (RR) was used as the effect measure in a random effects model. Sensitivity analysis, subgroup analysis, and calculation of publication bias were conducted...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28421375/obstructive-sleep-apnea-increases-the-risk-of-cardiac-events-after-percutaneous-coronary-intervention-a-meta-analysis-of-prospective-cohort-studies
#9
REVIEW
Hua Qu, Ming Guo, Ying Zhang, Da-Zhuo Shi
PURPOSE: Recent studies have shown an association between obstructive sleep apnea (OSA) and coronary artery disease; however, the association between OSA and cardiac outcomes in patients after percutaneous coronary intervention (PCI) remains undetermined. METHODS: PubMed, EMBASE, and CENTRAL were searched from inception to July 2016 for cohort studies that followed up with patients after PCI, and evaluated their overnight sleep patterns within 1 month for major adverse cardiac events (MACEs) as primary outcomes including cardiac death, non-fatal myocardial infarction (MI), and coronary revascularization and secondary outcomes including re-admission for heart failure and stroke...
April 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28419334/effect-of-a-low-crude-protein-diet-supplemented-with-different-levels-of-threonine-on-growth-performance-carcass-traits-blood-parameters-and-immune-responses-of-growing-broilers
#10
Samantha Sigolo, Zahra Zohrabi, Antonio Gallo, Alireza Seidavi, Aldo Prandini
A study was conducted to evaluate growth performance, carcass traits, blood serum parameters, and immune responses of Ross 308 male broilers fed diets containing 2 different crude protein (CP) levels (97.5 and 100%) and 4 threonine (Thr) levels (100, 110, 120, and 130% of Ross recommendations for starter and grower periods). A completely randomized block design was adopted and main effects (CP and Thr) were arranged in a 2 × 4 factorial approach. Optimum growth performance was achieved when broiler requirements for CP and Thr were 100% satisfied...
April 17, 2017: Poultry Science
https://www.readbyqxmd.com/read/28417679/synergy-or-interference-of-a-h9n2-avian-influenza-virus-with-a-velogenic-newcastle-disease-virus-in-chickens-are-dose-dependent
#11
Francesco Bonfante, Giovanni Cattoli, Sofia Leardini, Angela Salomoni, Eva Mazzetto, Irit Davidson, Ruth Haddas, Calogero Terregino
Field observations indicate that the impact of velogenic Newcastle disease virus (vNDV) is more severe in countries with concomitant circulation of LPAI virus, as is the case in the Middle East, in particular in Israel, where H9N2 and NDV are endemic. In our study, we evaluated how the exposure of chickens to a H9N2 challenge either favors or interferes with a subsequent vNDV infection and its transmission to sentinels. For this purpose, single vNDV and sequential H9/NDV challenges were performed with increasing doses of vNDV (10(1)-10(6) EID50)...
April 18, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28416500/cluster-randomised-controlled-trial-of-a-consumer-behaviour-intervention-to-improve-healthy-food-purchases-from-online-canteens-study-protocol
#12
Tessa Delaney, Rebecca Wyse, Sze Lin Yoong, Rachel Sutherland, John Wiggers, Kylie Ball, Karen Campbell, Chris Rissel, Luke Wolfenden
INTRODUCTION: School canteens represent an opportune setting in which to deliver public health nutrition strategies given their wide reach, and frequent use by children. Online school canteen ordering systems, where students order and pay for their lunch online, provide an avenue to improve healthy canteen purchases through the application of consumer behaviour strategies that impact on purchasing decisions. The aim of this study is to assess the efficacy of a consumer behaviour intervention implemented in an online school canteen ordering system in reducing the kilojoule, saturated fat, sugar and sodium content of primary student lunch orders...
April 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28415990/prognostic-value-of-pretreatment-standardized-uptake-value-of-f-18-fluorodeoxyglucose-pet-in-patients-with-gastric-cancer-a-meta-analysis
#13
Zhonghua Wu, Junhua Zhao, Peng Gao, Yongxi Song, Jingxu Sun, Xiaowan Chen, Bin Ma, Zhenning Wang
BACKGROUND: F-18- fluorodeoxyglucose Positron emission tomography ((18)FDG-PET) has been widely used in clinical practice. However, the prognostic value of the pretreatment standardized uptake value (SUV) for patients with gastric cancer remains controversial. METHODS: Major databases were systematically searched. The quality of the included studies was assessed using the Newcastle-Ottawa scale; the PET protocols were also evaluated. The pooled hazard ratio (HR) for overall survival (OS) and recurrence-free survival (RFS) were used to estimate the effect size...
April 17, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28412996/laparoscopic-surgery-versus-open-resection-in-patients-with-gastrointestinal-stromal-tumors-an-updated-systematic-review-and-meta-analysis
#14
Hanchu Xiong, Ji Wang, Yunlu Jia, Chenyang Ye, Yi Lu, Cong Chen, Jianguo Shen, Yongxia Chen, Wenhe Zhao, Linbo Wang, Jichun Zhou
PURPOSES: The contemporary surgery has reported the safety of laparoscopic surgery (LAP) for patients with gastrointestinal stromal tumors (GISTs). However, its use is still debated due to suspicion of the oncologic equivalence to open surgery (OPEN). We conducted a systematic review and meta-analysis of updated original articles to investigate the short- and long-term clinical outcomes of LAP compared with OPEN for GISTs. METHODS: A systematic search was performed in PubMed, Embase, Web of Science, Cochrane Library and CNKI...
April 5, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28411874/-association-between-radiation-from-mobile-phones-and-tumour-risk-in-adults
#15
Patricia Bielsa-Fernández, Beatriz Rodríguez-Martín
OBJECTIVE: To synthesize and analyse systematic reviews, case-control studies, cohort studies and meta-analysis that investigate the association between exposure to radiofrequency from mobile phones and the appearance of tumours in adults. METHODS: A systematic search was conducted in Scopus, Web of Science, The Cochrane Library, Medline and Cinahl of articles published in English and Spanish between January 2005 and February 2016 that analyse the risk of tumour associated with exposure to radiofrequency from mobile phones in adults...
April 12, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28409522/serological-biomarkers-as-risk-factors-of-sle-associated-pulmonary-arterial-hypertension-a-systematic-review-and-meta-analysis
#16
J Wang, J Qian, Y Wang, J Zhao, Q Wang, Z Tian, M Li, X Zeng
Objective This article aims to determine the serological biomarkers which can be considered as risk factors of systemic lupus erythematosus (SLE)-associated pulmonary arterial hypertension by a systematic review and meta-analysis. Methods This study was conducted in accordance with the PRISMA statement. The search database included MEDLINE, EMBASE, Cochrane Library and Scopus. The Newcastle-Ottawa scale was used for the quality assessment. The odds ratio was the primary measure of effect of the risk factors...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28407024/the-prognosis-of-infective-endocarditis-treated-with-biological-valves-versus-mechanical-valves-a-meta-analysis
#17
Ende Tao, Li Wan, WenJun Wang, YunLong Luo, JinFu Zeng, Xia Wu
OBJECTIVE: Surgery remains the primary form of treatment for infective endocarditis (IE). However, it is not clear what type of prosthetic valve provides a better prognosis. We conducted a meta-analysis to compare the prognosis of infective endocarditis treated with biological valves to cases treated with mechanical valves. METHODS: Pubmed, Embase and Cochrane databases were searched from January 1960 to November 2016.Randomized controlled trials, retrospective cohorts and prospective studies comparing outcomes between biological valve and mechanical valve management for infective endocarditis were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28406464/vitamin-d-status-muscle-strength-and-physical-performance-decline-in-very-old-adults-a-prospective-study
#18
Antoneta Granic, Tom R Hill, Karen Davies, Carol Jagger, Ashley Adamson, Mario Siervo, Thomas B L Kirkwood, John C Mathers, Avan A Sayer
Mixed reports exist about the role of 25-hydroxyvitamin D (25(OH)D) in muscle ageing and there are few prospective studies involving the very old (aged ≥ 85) who are at highest risk of low 25(OH)D, loss of muscle mass and strength, and physical performance decline. In the Newcastle 85+ Study (n = 845), we aimed to determine the association between 25(OH)D season-specific quartiles (hereafter SQ1-SQ4), grip strength (GS) and physical performance decline (Timed Up-and-Go Test, TUG) over 5 years using mixed models...
April 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28403088/changes-of-transforming-growth-factor-beta-1-in-patients-with-type-2-diabetes-and-diabetic-nephropathy-a-prisma-compliant-systematic-review-and-meta-analysis
#19
Yong-Chao Qiao, Yin-Ling Chen, Yan-Hong Pan, Wei Ling, Fang Tian, Xiao-Xi Zhang, Hai-Lu Zhao
BACKGROUND: The existing evidence indicates increased levels of transforming growth factor beta 1 (TGF-β1) in patients with type 2 diabetes mellitus (T2DM) and those with type 2 diabetic nephropathy (T2DN); yet no meta-analysis displays a reliable result. Here we conducted a meta-analysis to evaluate characteristic changes of TGF-β1 in T2DM and diabetic nephropathy. METHODS: A systematic search was conducted for eligible studies, which reported the association of TGF-β1 withT2DM and T2DN patients, in PubMed, Wangfang, Chinese-Cqvip, and China National Knowledge Infrastructure database, from February 1, 1991 to December 15, 2015...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28402417/grandmaternal-smoke-exposure-reduces-female-fertility-in-a-murine-model-with-great-grandmaternal-smoke-exposure-unlikely-to-have-an-effect
#20
N J Camlin, A G Jarnicki, R L Vanders, K A Walters, P M Hansbro, E A McLaughlin, J E Holt
STUDY QUESTION: What effect does multigenerational (F2) and transgenerational (F3) cigarette smoke exposure have on female fertility in mice? SUMMARY ANSWER: Cigarette smoking has a multigenerational effect on female fertility. WHAT IS KNOWN ALREADY: It has been well established that cigarette smoking decreases female fertility. Furthermore, a growing body of evidence suggests that smoking during pregnancy decreases the fertility of daughters and increases cancer and asthma incidence in grandchildren and great-grandchildren...
April 10, 2017: Human Reproduction
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