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Trigger point injections

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https://www.readbyqxmd.com/read/29125184/hepatic-and-hippocampal-cytochrome-p450-enzyme-overexpression-during-spontaneous-recurrent-seizures
#1
Leonie Runtz, Benoit Girard, Marion Toussenot, Julie Espallergues, Alexis Fayd'Herbe De Maudave, Alexandre Milman, Frederic deBock, Chaitali Ghosh, Nathalie C Guérineau, Jean-Marc Pascussi, Federica Bertaso, Nicola Marchi
OBJECTIVE: Available evidence points to a role of cytochrome P450 (Cyp) drug biotransformation enzymes in central nervous system diseases, including epilepsy. Deviations in drug pharmacokinetic profiles may impact therapeutic outcomes. Here, we ask whether spontaneous recurrent seizure (SRS) activity is sufficient to modulate the expression of major Cyp enzymes in the liver and brain. METHODS: Unilateral intrahippocampal (IH) kainic acid (KA) injections were used to elicit nonconvulsive status epilepticus (SE), epileptogenesis, and SRS, as monitored by video-electroencephalography...
November 10, 2017: Epilepsia
https://www.readbyqxmd.com/read/29102137/evaluation-of-glucose-dose-on-intravenous-glucose-tolerance-test-traits-in-holstein-friesian-heifers
#2
L Antonio González-Grajales, Laura Pieper, Sebastian Mengel, Rudolf Staufenbiel
Glucose metabolism in dairy and beef cattle has received considerable attention because balanced blood glucose is essential for numerous processes, such as milk production and general health. The glucose tolerance test measures the ability of an organism to regulate blood glucose levels. Glucose half-life time (GHLT) has high heritability and could serve as a potential parameter to breed for metabolic resistance. However, studies focusing on identification of an adequate glucose dose have not yet been conducted in cattle...
October 25, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29078865/effectiveness-safety-and-predictors-of-response-to-botulinum-toxin-type-a-in-refractory-masticatory-myalgia-a-retrospective-study
#3
Shehryar N Khawaja, Steven J Scrivani, Nicole Holland, David A Keith
PURPOSE: Masticatory muscle pain disorders respond well to conservative therapy; however, in some patients the pain becomes refractory. Botulinum toxin type A (BoT-A) therapy has been shown to be an effective modality in the management of refractory headache disorders. Conversely, there are conflicting reports in the literature regarding the efficacy, safety, and predictors of therapeutic response to BoT-A therapy for management of refractory masticatory muscle pain. MATERIALS AND METHODS: We performed a retrospective chart review of patients who underwent at least 2 injection cycles of 100 U of BoT-A for refractory masticatory myalgia in the Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, between May 2012 and June 2016...
November 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29037652/the-local-twitch-response-during-trigger-point-dry-needling-is-it-necessary-for-successful-outcomes
#4
Thomas Perreault, James Dunning, Raymond Butts
BACKGROUND: Myofascial trigger point (MTrP) injection and trigger point dry needling (TrPDN) are widely accepted therapies for myofascial pain syndrome (MPS). Empirical evidence suggests eliciting a local twitch response (LTR) during needling is essential. OBJECTIVE: This is the first review exploring the available literature, regardless of study design, on the neurophysiological effects and clinical significance of the LTR as it relates to reductions in pain and disability secondary to MTrP needling...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29026893/descending-necrotizing-mediastinitis-after-a-trigger-point-injection
#5
Jae Young Choe, Jong Kun Kim, Dong Eun Lee, Kang Suk Seo, Jung Bae Park, Mi Jin Lee, Hyun Wook Ryoo, Jae Yun Ahn, Sungbae Moon
Descending necrotizing mediastinitis (DNM) is a rare form of mediastinal infection. Most cases are associated with esophageal rupture. DNM after a trigger point injection in the upper trapezius has not been described previously. We present a case of DNM after a trigger point injection in the upper trapezius. A 70-year-old man visited the emergency department with chest discomfort and fever after a trigger point injection in the left upper trapezius. Chest computed tomography showed evidence of DNM, and antibiotic therapy was immediately administered intravenously...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28990015/efficacy-of-the-twin-block-a-peripheral-nerve-block-for-the-management-of-chronic-masticatory-myofascial-pain-a-case-series
#6
Veena Kanti, Sowmya Ananthan, Gayathri Subramanian, Samuel Y P Quek
Masticatory myofascial pain is the one of the most common etiologies for nonodontogenic pain, often characterized by the presence of trigger points. Conventional management includes approaches such as jaw exercises, physical therapy, intraoral appliances, medications, and trigger point injections. Peripheral/regional nerve blocks have shown to be effective in managing myogenous pain conditions. The twin block is a nerve block that blocks both the masseteric and the anterior deep temporal nerves. The objective of this case series is to illustrate expeditious and sustained efficacy of the twin block in the management of chronic masticatory myofascial pain...
October 6, 2017: Quintessence International
https://www.readbyqxmd.com/read/28988103/opioid-tapering-in-patients-with-prescription-opioid-use-disorder-a-retrospective-study
#7
Kehua Zhou, Peng Jia, Swati Bhargava, Yong Zhang, Taslima Reza, Yuan Bo Peng, Gary G Wang
BACKGROUND AND AIMS: Opioid use disorder (OUD) refers to a maladaptive pattern of opioid use leading to clinically significant impairment or distress. OUD causes, and vice versa, misuses and abuse of opioid medications. Clinicians face daily challenges to treat patients with prescription opioid use disorder. An evidence-based management for people who are already addicted to opioids has been identified as the national priority in the US; however, options are limited in clinical practices...
October 4, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28980273/specialized-pain-clinics-in-primary-care-common-diagnoses-referral-patterns-and-clinical-outcomes-novel-pain-management-model
#8
Yacov Fogelman, Eli Carmeli, Amir Minerbi, Baruch Harash, Simon Vulfsons
An estimated 19% of the adult population in western countries lives with chronic pain. Pain management lies mainly within the primary care and community setting. We evaluated the outcome of a new model of secondary care clinics, conducted by primary care physicians with specialized training in pain medicine. Data on referral patterns, prevalence of pain diagnosis, and medication consumption were recorded at five secondary pain management clinics in the community setting. In total, 997 patients with pain attended 2,652 visits (average 2...
October 5, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28974951/nutritional-immunity-triggers-the-modulation-of-iron-metabolism-genes-in-the-sub-antarctic-notothenioid-eleginops-maclovinus-in-response-to-piscirickettsia-salmonis
#9
Danixa Martínez, Ricardo Oyarzún, Juan Pablo Pontigo, Alex Romero, Alejandro J Yáñez, Luis Vargas-Chacoff
Iron deprivation is a nutritional immunity mechanism through which fish can limit the amount of iron available to invading bacteria. The aim of this study was to evaluate the modulation of iron metabolism genes in the liver and brain of sub-Antarctic notothenioid Eleginops maclovinus challenged with Piscirickettsia salmonis. The specimens were inoculated with two P. salmonis strains: LF-89 (ATCC(®) VR-1361™) and Austral-005 (antibiotic resistant). Hepatic and brain samples were collected at intervals over a period of 35 days...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28971042/extracorporeal-shock-wave-therapy-versus-trigger-point-injection-in-the-treatment-of-myofascial-pain-syndrome-in-the-quadratus-lumborum
#10
Jin Oh Hong, Joon Sang Park, Dae Geun Jeon, Wang Hyeon Yoon, Jung Hyun Park
OBJECTIVE: To compare the effectiveness of extracorporeal shock wave therapy (ESWT) and trigger point injection (TPI) for the treatment of myofascial pain syndrome in the quadratus lumborum. METHODS: In a retrospective study at our institute, 30 patients with myofascial pain syndrome in the quadratus lumborum were assigned to ESWT or TPI groups. We assessed ESWT and TPI treatment according to their affects on pain relief and disability improvement. The outcome measures for the pain assessment were a visual analogue scale score and pain pressure threshold...
August 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28971041/characteristics-of-myofascial-pain-syndrome-of-the-infraspinatus-muscle
#11
Junbeom Kwon, Hyoung Seop Kim, Won Hyuk Chang, Chunung Park, Sang Chul Lee
OBJECTIVE: To report the characteristics of myofascial trigger points (MTrPs) in the infraspinatus muscle and evaluate the therapeutic effect of trigger-point injections. METHODS: Medical records of 297 patients (221 women; age, 53.9±11.3 years) with MTrPs in the infraspinatus muscle were reviewed retrospectively. Because there were 83 patients with MTrPs in both infraspinatus muscles, the characteristics of total 380 infraspinatus muscles with MTrPs (214 one side, 83 both sides) were investigated...
August 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28953648/intramuscular-hematoma-with-motor-weakness-after-trigger-point-injection-a-case-report
#12
Sang Gyun Kim, Kwang Seok Shim, Dong Won Lee, Eun Ju Kim, Sang-Gon Lee, Ji-Hyang Lee, Ji Hyun An
RATIONALE: Although trigger point injection is known as an easy and low-risk procedure, it is contraindicated to patients with hemorrhagic disorders or who regularly take anticoagulants/antiplatelets. However, taking clopidogrel is not a defined contraindication to this low-risk procedure. PATIENT CONCERNS: The chief complaint of a 76-year old woman regularly taking clopidogrel was low back and left buttock pain which prolonged for several years. DIAGNOSES: The patient was diagnosed with L4-5 and L5-S1 spinal stenosis at the orthopedics department and was referred for lumbar spinal epidural steroid injection...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28942118/carpal-tunnel-syndrome-effectiveness-of-physical-therapy-and-electrophysical-modalities-an-updated-systematic-review-of-randomized-controlled-trials
#13
REVIEW
Bionka M A Huisstede, Peter Hoogvliet, Thierry P C Franke, Manon S Randsdorp, Bart W Koes
OBJECTIVE: To review scientific literature studying the effectiveness of physical therapy and electrophysical modalities for carpal tunnel syndrome (CTS). DATA SOURCES: The Cochrane Library, PubMed, EMBASE, CINAHL, and PEDro. STUDY SELECTION: Two reviewers independently applied the inclusion criteria to select potential eligible studies. DATA EXTRACTION: Two reviewers independently extracted the data and assessed the methodological quality using the Cochrane Risk of Bias Tool...
September 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28934793/acupuncture-for-myofascial-pain-syndrome-a-network-meta-analysis-of-33-randomized-controlled-trials
#14
Xiuxia Li, Rong Wang, Xin Xing, Xiue Shi, Jinhui Tian, Jun Zhang, Long Ge, Jingyun Zhang, Lun Li, Kehu Yang
BACKGROUND: Acupuncture techniques are commonly used as initial treatments for myofascial pain syndrome. OBJECTIVE: This study aimed to assess and compare the efficacy and safety of different techniques of acupuncture for myofascial pain syndrome. STUDY DESIGN: Network meta-analysis. SETTING: All selected studies were randomized controlled trials (RCTs). METHODS: The Cochrane Central Register of Controlled Trials, PubMed, Web of Science, EMBASE, and Chinese Biomedical Literature Database were searched from their inceptions to February 2016...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28893414/transcriptional-mediated-effects-of-radiation-on-the-expression-of-immune-susceptibility-markers-in-melanoma
#15
Lauryn R Werner, Jasdeep S Kler, Monica M Gressett, Maureen Riegert, Lindsey K Werner, Clinton M Heinze, Joseph G Kern, Mahyar Abbariki, Amy K Erbe, Ravi B Patel, Raghava N Sriramaneni, Paul M Harari, Zachary S Morris
BACKGROUND AND PURPOSE: We recently reported a time-sensitive, cooperative, anti-tumor effect elicited by radiation (RT) and intra-tumoral-immunocytokine injection in vivo. We hypothesized that RT triggers transcriptional-mediated changes in tumor expression of immune susceptibility markers at delayed time points, which may explain these previously observed time-dependent effects. MATERIALS AND METHODS: We examined the time course of changes in expression of immune susceptibility markers following in vitro or in vivo RT in B78 murine melanoma and A375 human melanoma using flow cytometry, immunoblotting, and qPCR...
September 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28889841/hwanglyunhaedok-pharmacopuncture-versus-saline-pharmacopuncture-on-chronic-nonbacterial-prostatitis-chronic-pelvic-pain-syndrome
#16
Kee Moon Seong, Geurin Jang, Dong Woong Kim, Sungchul Kim, Bong Keun Song
PURPOSE: Chronic nonbacterial prostatitis (CP)/chronic pelvic pain syndrome (CPPS) is known not to have a successful therapy as yet. More recently, acupuncture, some herbal compounds, and trigger point injection have been reported to be beneficial. Pharmacopuncture is an herbal acupuncture having these benefits. The aim of this study was to compare the effect of HP (Hwanglyunhaedok Pharmacopuncture) versus normal saline injection (Saline Pharmacopuncture, SP) on CP/CPPS. METHODS: A retrospective follow up study of 63 patients who were diagnosed with CP/CPPS was performed...
August 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28888095/magnesium-therapy-improves-outcome-in-streptococcus-pneumoniae-meningitis-by-altering-pneumolysin-pore-formation
#17
Sabrina Hupp, Sandra Ribes, Jana Seele, Carolin Bischoff, Christina Förtsch, Elke Maier, Roland Benz, Timothy J Mitchell, Roland Nau, Asparouh I Iliev
BACKGROUND AND PURPOSE: Streptococcus pneumoniae is the most common cause of bacterial meningitis in adults and is characterized by high lethality and substantial cognitive disabilities in survivors. Here, we have studied the capacity of an established therapeutic agent, magnesium, to improve survival in pneumococcal meningitis by modulating the neurological effects of the major pneumococcal pathogenic factor, pneumolysin. EXPERIMENTAL APPROACH: We used mixed primary glial and acute brain slice cultures, pneumolysin injection in infant rats, a mouse meningitis model and complementary approaches such as Western blot, a black lipid bilayer conductance assay and live imaging of primary glial cells...
September 9, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28858275/-botulinus-toxin-in-complex-treatment-of-myofacial-pain-syndrome
#18
S N Fedotov, M A Gerasimova, S D Shorokhov, A I Tischenko
The aim of the study was to assess the efficacy of type A Botulinus toxin (BTA) in pain release by TMJ functional pain disorders. The study included 211 patients with TMJ functional pain disorder (20.4% males and 79.6% females; mean age 45.3 years). The patients underwent clinical examination and bioelectric activity assessment of masticatory muscles by electromyography (EMG). EMG specters of 20 healthy volunteers with intact dental arches served as a control. After examination BTA was injected in muscular pain trigger points...
2017: Stomatologii︠a︡
https://www.readbyqxmd.com/read/28854498/dorsal-scapular-nerve-injury-after-trigger-point-injection-into-the-rhomboid-major-muscle-a-case-report
#19
Dong Gyu Lee, Min Cheol Chang
BACKGROUND AND OBJECTIVE: We report the case of a patient who presented with right dorsal scapular neuropathy after a trigger point injection into the right rhomboid major muscle. Through a nerve conduction study and electromyography, we demonstrated dorsal scapular nerve injury in this patient. CASE REPORT: A 38-year-old man complained that his right shoulder functioned less optimally during push-up exercises after a trigger point injection 4 weeks prior. Physical examination revealed mildly reduced right shoulder retractor muscle strength compared with the left side...
August 14, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28814464/on-the-transition-from-reconsolidation-to-extinction-of-contextual-fear-memories
#20
Lindsey F Cassini, Charlotte R Flavell, Olavo B Amaral, Jonathan L C Lee
Retrieval of an associative memory can lead to different phenomena. Brief reexposure sessions tend to trigger reconsolidation, whereas more extended ones trigger extinction. In appetitive and fear cued Pavlovian memories, an intermediate "null point" period has been observed where neither process seems to be engaged. Here we investigated whether this phenomenon extends to contextual fear memory. Adult rats were subjected to a contextual fear conditioning paradigm, reexposed to the context 2 d later for 3, 5, 10, 20, or 30 min, with immediate injections of MK-801 or saline following reexposure, and tested on the following day...
September 2017: Learning & Memory
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