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Trigger point injections

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https://www.readbyqxmd.com/read/28293532/anatomical-regional-targeted-art-botox-injection-technique-a-novel-paradigm-for-migraines-and-chronic-headaches
#1
Bardia Amirlak, Kyle Sanniec, Ronnie Pezeshk, Michael Chung
Migraine headaches are a debilitating disease that causes significant socioeconomic problems. One of the speculated etiologies of the generation of migraines is peripheral nerve irritation at different trigger points. The use of Onabotulinum toxin A (BOTOX), although initially a novel approach, has now been determined to be a valid treatment for chronic headaches and migraines as described in the Phase III Research Evaluating Migraine Prophylaxis Therapy trials that prompted the approval by the Food and Drug Administration for treatment of chronic migraines...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28277418/ultrasound-guided-interventional-procedures-myofascial-trigger-points-with-structured-literature-review
#2
Dinesh Kumbhare, Dhanveer Singh, Alasdair Rathbone H, Madison Gunn, Liza Grosman-Rimon, Brian Vadasz, Hance Clarke, Philip W H Peng
Ultrasound-guided injections in pain medicine are a common intervention. They have been used to manage myofascial trigger points (MTrPs) in different muscles of the body. The main objectives of this article were to review ultrasound-guided injection techniques used for treating MTrPs. We also summarize the anatomy and sonoanatomy of MTrPs using the upper trapezius muscle as an example.
March 8, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28261683/botox-combined-with-myofascial-release-physical-therapy-as-a-treatment-for-myofascial-pelvic-pain
#3
Gabriela E Halder, Lauren Scott, Allison Wyman, Nelsi Mora, Branko Miladinovic, Renee Bassaly, Lennox Hoyte
PURPOSE: To report the effects of combined onabotulinumtoxinA (Botox) injections and myofascial release physical therapy on myofascial pelvic pain (MFPP) by comparing pre- and posttreatment average pelvic pain scores, trigger points, and patient self-reported pelvic pain. Secondary outcomes were to examine posttreatment complications and determine demographic differences between patients with/without an improvement in pain. MATERIALS AND METHODS: This was an Institutional Review Board approved retrospective case series on women over 18 years with MFPP who received Botox and physical therapy between July 2006 and November 2014...
March 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28246896/melatonin-reduces-motivation-for-cocaine-self-administration-and-prevents-relapse-like-behavior-in-rats
#4
Tatiane T Takahashi, Valentina Vengeliene, Rainer Spanagel
RATIONALE: Melatonin is a hormone involved in the entrainment of circadian rhythms, which appears dysregulated in drug users. Further, it has been demonstrated that melatonin can modulate the reinforcing effects of several drugs of abuse and may therefore play a role in drug addiction. OBJECTIVE: Here, we investigated whether administration of melatonin reduces relapse-like behavior and the motivation to seek cocaine in rats. METHODS: Male Sprague-Dawley rats were submitted to long-term cocaine self-administration training...
February 28, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28201874/noise-induced-and-control-of-collective-behavior-in-a-population-of-coupled-chemical-oscillators
#5
Alberto P Muñuzuri, Juan Pérez-Mercader
Synchronization of intercommunicating individual oscillators is an important form of collective behavior used in nature as a mechanism to face dangers, act collectively, and communicate. The involvement of the medium where oscillators exist is an important ingredient. Because of their nature and their multiple different components, the medium and the environment are often perceived as stochastic relative to the deterministic nature of the individuals on some scale. This injects energy/matter into the system in ways that can enhance or de-enhance communication in a stochastic manner...
February 28, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28193791/epinephrine-for-first-aid-management-of-anaphylaxis
#6
Scott H Sicherer, F Estelle R Simons
Anaphylaxis is a severe, generalized allergic or hypersensitivity reaction that is rapid in onset and may cause death. Epinephrine (adrenaline) can be life-saving when administered as rapidly as possible once anaphylaxis is recognized. This clinical report from the American Academy of Pediatrics is an update of the 2007 clinical report on this topic. It provides information to help clinicians identify patients at risk of anaphylaxis and new information about epinephrine and epinephrine autoinjectors (EAs). The report also highlights the importance of patient and family education about the recognition and management of anaphylaxis in the community...
March 2017: Pediatrics
https://www.readbyqxmd.com/read/28167178/chronic-pain-in-a-patient-with-ehlers-danlos-syndrome-hypermobility-type-the-role-of-myofascial-trigger-point-injections
#7
Saipriya Tewari, Rajashree Madabushi, Anil Agarwal, Sujeet K Gautam, Sandeep Khuba
Chronic widespread musculoskeletal pain is a cardinal symptom in hypermobility type of Ehler Danlos Syndrome (EDS type III). The management of pain in EDS, however, has not been studied in depth. A 30 year old female, known case of EDS, presented to the pain clinic with complaints of severe upper back pain for 6 months. Physical examination of the back revealed two myofascial trigger points over the left rhomboids and the left erector spinae. Local anaesthetic trigger point injections were given at these points, followed by stretching exercises under analgesic cover for the first week...
January 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28162636/-388-combination-of-trigger-point-injection-applied-to-the-mid-and-upper-trapezius-and-shoulder-injection-in-the-management-of-exacerbation-of-shoulder-pain
#8
Z Elchami, M Issa, R Massoud, A Mirambel, E Diaz
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28161653/low-level-laser-therapy-lllt-accelerates-the-sternomastoid-muscle-regeneration-process-after-myonecrosis-due-to-bupivacaine
#9
Cristiane Neves Alessi Pissulin, Ana Angélica Henrique Fernandes, Alejandro Manuel Sanchez Orellana, Renata Calciolari Rossi E Silva, Selma Maria Michelin Matheus
BACKGROUND: Because of its long-lasting analgesic action, bupivacaine is an anesthetic used for peripheral nerve block and relief of postoperative pain. Muscle degeneration and neurotoxicity are its main limitations. There is strong evidence that low-level laser therapy (LLLT) assists in muscle and nerve repair. The authors evaluated the effects of a Gallium Arsenide laser (GaAs), on the regeneration of muscle fibers of the sternomastoid muscle and accessory nerve after injection of bupivacaine...
January 26, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28144159/anterior-cutaneous-nerve-entrapment-syndrome-management-challenges
#10
REVIEW
Eleni Chrona, Georgia Kostopanagiotou, Dimitrios Damigos, Chrysanthi Batistaki
Anterior cutaneous nerve entrapment syndrome (ACNES) is a commonly underdiagnosed and undertreated chronic state of pain. This syndrome is characterized by the entrapment of the cutaneous branches of the lower thoracoabdominal intercostal nerves at the lateral border of the rectus abdominis muscle, which causes severe, often refractory, chronic pain. This narrative review aims to identify the possible therapeutic strategies for the management of the syndrome. Seventeen studies about ACNES therapy were reviewed; of them, 15 were case-control studies, case series, or case reports, and two were randomized controlled trials...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28128086/vesicular-contact-reaction-may-progress-into-erythema-multiforme
#11
Magdalena Czarnecka-Operacz, Dorota Jenerowicz, Joanna Szulczyńska-Gabor, Ewa Teresiak-Mikołajczak, Joanna Szyfter-Harris, Monika Bowszyc-Dmochowska
Dear Editor, Erythema multiforme is considered an acute skin condition, characterized by a self-limiting and sometimes recurrent course. It is regarded as a type IV hypersensitivity reaction associated with certain infections, medications, and other various triggers. Allergic contact dermatitis is in turn a delayed type of induced allergy as a result of cutaneous contact with a specific allergen to which the patient develops specific sensitivity. This type of cutaneous reaction is associated with inflammation manifesting with erythema, edema, and vesicles...
December 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28053042/induction-of-migraine-like-photophobic-behavior-in-mice-by-both-peripheral-and-central-cgrp-mechanisms
#12
Bianca N Mason, Eric A Kaiser, Adisa Kuburas, Maria-Cristina M Loomis, John A Latham, Leon F Garcia-Martinez, Andrew F Russo
The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine. Although migraine can be treated using CGRP antagonists that act peripherally, the relevant sites of CGRP action remain unknown. To address the role of CGRP both within and outside the CNS, we used CGRP-induced light-aversive behavior in mice as a measure of migraine-associated photophobia. Peripheral (intraperitoneal) injection of CGRP resulted in light-aversive behavior in wild-type CD1 mice similar to aversion seen previously after central (intracerebroventricular) injection...
January 4, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28049214/relating-chronic-pelvic-pain-and-endometriosis-to-signs-of-sensitization-and-myofascial-pain-and-dysfunction
#13
Jacqueline V Aredo, Katrina J Heyrana, Barbara I Karp, Jay P Shah, Pamela Stratton
Chronic pelvic pain is a frustrating symptom for patients with endometriosis and is frequently refractory to hormonal and surgical management. While these therapies target ectopic endometrial lesions, they do not directly address pain due to central sensitization of the nervous system and myofascial dysfunction, which can continue to generate pain from myofascial trigger points even after traditional treatments are optimized. This article provides a background for understanding how endometriosis facilitates remodeling of neural networks, contributing to sensitization and generation of myofascial trigger points...
January 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28025351/immediate-adverse-events-in-interventional-pain-procedures-a-multi-institutional-study
#14
Carrie M Carr, Christopher T Plastaras, Matthew J Pingree, Matthew Smuck, Timothy P Maus, Jennifer R Geske, Christine A El-Yahchouchi, Zachary L McCormick, David J Kennedy
SETTING: Interventional procedures directed toward sources of pain in the axial and appendicular musculoskeletal system are performed with increasing frequency. Despite the presence of evidence-based guidelines for such procedures, there are wide variations in practice. Case reports of serious complications such as spinal cord infarction or infection from spine injections lack appropriate context and create a misleading view of the risks of appropriately performed interventional pain procedures...
December 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28006998/supraventricular-tachycardia-during-the-first-year-of-life-is-subclinical-inflammation-the-trigger
#15
Pier Paolo Bassareo, Vassilios Fanos, Mario Pala, Luca Antonucci, Paola Neroni, Roberto Antonucci, Guseppe Mercuro
BACKGROUND: Neutrophil/lymphocyte ratio (NLR) and red cell distribution width (RDW) may be associated with the onset of arrhythmias in adults, thus underlining a possible inflammatory etiology. Paroxysmal supraventricular tachycardia (SVT) is the most frequent pathological tachycardia in childhood. AIM: To verify NLR and RDW levels in a group of children (<1 year) affected by SVT with a structurally normal heart and without fever or inflammatory diseases; to compare NLR and RDW before and after SVT resolution, to verify whether the latter was related with the reduction in inflammatory state; to identify - in SVT subtypes caused by a reentry mechanism - an NLR and RDW cutoff point beyond which adenosine was ineffective in preventing SVT recurrence...
January 12, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27919595/the-starting-point-for-bisphosphonate-related-osteonecrosis-of-the-jaw-alveolar-bone-or-oral-mucosa-a-randomized-controlled-experimental-study
#16
Mohammad Zandi, Arash Dehghan, Pejman Janbaz, Hamid Malekzadeh, Payam Amini
OBJECTIVE: Although over a decade has passed since first introduction of BRONJ, the exact pathophysiology of this disease is still unclear. The present experimental study aimed to determine whether the oral mucosa or alveolar bone serves as the starting point for BRONJ development. SUBJECTS AND METHODS: Sixty male Wistar rats were randomly assigned into study and control groups (each, n = 30), and received intraperitoneal injection of 0.06 mg/kg zoledronate and saline, respectively, once a week for 12 weeks...
January 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27909097/induction-of-migraine-like-photophobic-behavior-in-mice-by-both-peripheral-and-central-cgrp-mechanisms
#17
Bianca N Mason, Eric A Kaiser, Adisa Kuburas, Maria-Cristina M Loomis, John A Latham, Leon F Garcia-Martinez, Andrew F Russo
The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine. While migraine can be treated using CGRP antagonists that act peripherally, the relevant sites of CGRP action remain unknown. To address the role of CGRP both within and outside the central nervous system, we used CGRP-induced light aversive behavior in mice as a measure of migraine-associated photophobia. Peripheral (intraperitoneal, IP) injection of CGRP resulted in light aversive behavior in wild-type CD1 mice similar to aversion previously seen following central (intracerebroventricular, ICV) injection...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27898454/transvaginal-pelvic-floor-muscle-injection-technique-a-cadaver-study
#18
Priyanka Gupta, Michael Ehlert, Larry T Sirls, Kenneth Peters
INTRODUCTION: Women with pelvic floor dysfunction can have tender areas on vaginal examination, which can be treated with trigger-point injections. There are no publications to evaluate the accuracy of pelvic floor muscle injections. METHODS: Trigger-point injections were performed on 2 fresh cadaveric pelvises using a curved nasal cannula guide and 7-in spinal needle. This was performed using our standard template of 2 sets of injections at the 1-, 3-, and 5-o'clock positions distally and proximally...
January 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27831558/ripk1-protects-from-tnf-%C3%AE-mediated-liver-damage-during-hepatitis
#19
Aveline Filliol, Claire Piquet-Pellorce, Jacques Le Seyec, Muhammad Farooq, Valentine Genet, Catherine Lucas-Clerc, John Bertin, Peter J Gough, Marie-Thérèse Dimanche-Boitrel, Peter Vandenabeele, Mathieu Jm Bertrand, Michel Samson
Cell death of hepatocytes is a prominent characteristic in the pathogenesis of liver disease, while hepatolysis is a starting point of inflammation in hepatitis and loss of hepatic function. However, the precise molecular mechanisms of hepatocyte cell death, the role of the cytokines of hepatic microenvironment and the involvement of intracellular kinases, remain unclear. Tumor necrosis factor alpha (TNF-α) is a key cytokine involved in cell death or survival pathways and the role of RIPK1 has been associated to the TNF-α-dependent signaling pathway...
November 10, 2016: Cell Death & Disease
https://www.readbyqxmd.com/read/27825520/versatility-of-a-localized-surface-plasmon-resonance-based-gold-nanoparticle-alloyed-quantum-dot-nanobiosensor-for-immunofluorescence-detection-of-viruses
#20
Kenshin Takemura, Oluwasesan Adegoke, Naoto Takahashi, Tatsuya Kato, Tian-Cheng Li, Noritoshi Kitamoto, Tomoyuki Tanaka, Tetsuro Suzuki, Enoch Y Park
Flu infection, caused by the influenza virus, constitutes a serious threat to human lives worldwide. A rapid, sensitive and specific diagnosis is urgently needed for point-of-care treatment and to control the rapid spread of this disease. In this study, an ultrasensitive, rapid and specific localized surface plasmon resonance (LSPR)-induced immunofluorescence nanobiosensor has been developed for the influenza virus based on a gold nanoparticle (AuNP)-induced quantum dot (QD) fluorescence signal. Alloyed quaternary CdSeTeS QDs were synthesized via the hot-injection organometallic route and were subsequently capped with l-cysteine via a ligand exchange reaction...
March 15, 2017: Biosensors & Bioelectronics
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