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Apnea hypopnea index

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https://www.readbyqxmd.com/read/28805272/clinical-phenotype-of-south-east-asian-temporomandibular-disorder-patients-with-upper-airway-resistance-syndrome
#1
David K L Tay, Kenny P Pang
OBJECTIVE: To document the clinical phenotype of temporomandibular disorder (TMD) patients with concomitant upper airway resistance syndrome (UARS) in a South East Asian population. STUDY DESIGN: A multi-center prospective series of 86 TMD patients (26 men and 60 women / mean age 35.7 years) with UARS. All had excessive daytime sleepiness, high arousal index and apnea-hypopnea index (AHI)<5 RESULTS: The mean body mass index was 20.1, mean arousal index 16.2, mean respiratory disturbance index 19...
August 14, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28802388/adenotonsillectomy-outcomes-in-children-with-sleep-apnea-and-narcolepsy
#2
Sneh Biyani, Tina D Cunningham, Cristina M Baldassari
OBJECTIVE: To identify improvements in daytime sleepiness following adenotonsillectomy in children with non-severe obstructive sleep apnea and narcolepsy. STUDY DESIGN: Case series with chart review over 15 years. SETTING: Tertiary Children's Hospital. SUBJECTS AND METHODS: Children between 6 and 17 years of age with narcolepsy that underwent adenotonsillectomy for non-severe obstructive sleep apnea (OSA) were included...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28802380/can-telemetry-data-obviate-the-need-for-sleep-studies-in-pierre-robin-sequence
#3
Nicole Leigh Aaronson, Noel Jabbour
OBJECTIVE: This study looks to correlate telemetry data gathered on patients with Pierre Robin Sequence (PRS) with sleep study data. Strong correlation might allow obstructive sleep apnea (OSA) to be reasonably predicted without the need for sleep study. METHODS: Charts from forty-six infants with PRS who presented to our children's hospital between 2005 and 2015 and received a polysomnogram (PSG) prior to surgical intervention were retrospectively reviewed. Correlations and scatterplots were used to compare average daily oxygen nadir, overall oxygen nadir, and average number of daily desaturations from telemetry data with apnea-hypopnea index (AHI) and oxygen nadir on sleep study...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28802366/formula-for-the-prediction-of-apnea-hypopnea-index-in-children-with-obstructive-sleep-apnea-without-polysomnography-according-to-the-clinical-parameters-is-it-reliable
#4
Zlatko Kljajić, Željka Roje, Kristijan Bečić, Vesna Čapkun, K Vilović, Petar Ivanišević, Eugenija Marušić
PURPOSE OF THE STUDY: The aim of the study was to propose "the risk formula" for obstructive sleep apnea in children according to the general and local clinical parameters and findings relevant for obstructive sleep apnea (OSA) severity. The unmet need for this formula arises from the economic burden of polysomnography (device, staff, training, special sleep centers, etc) as the golden standard for the diagnostics. MATERIALS AND METHODS USED: The study was performed from January 2013 until January 2016 in the Sleep Center, Department for Neuroscience, School of Medicine of the University of Split, Department of Pediatrics, University Hospital Split, Croatia and ENT Dept...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28800204/comparison-of-robotic-and-coblation-tongue-base-resection-for-obstructive-sleep-apnea
#5
Chi Sang Hwang, Jin Won Kim, Jin Woong Kim, Eun Jung Lee, Chang-Hoon Kim, Joo-Heon Yoon, Hyung-Ju Cho
OBJECTIVES: To compare the efficacy and safety of transoral robotic surgery (TORS) with endoscope-guided coblation tongue base resection. DESIGN: Retrospective case-control study. SETTING: University-based tertiary care medical center. PARTICIPANTS: OSA patients who underwent endoscope-guided tongue base coblation resection or TORS in combination with lateral pharyngoplasty at a single institution in South Korea between April 2013 and December 2016 were investigated...
August 11, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28800040/effect-of-continuous-positive-airway-pressure-in-hypertensive-patients-with-obstructive-sleep-apnea-and-high-urinary-metanephrines
#6
Luisa Gilardini, Carolina Lombardi, Gabriella Redaelli, Paola Mattaliano, Paolo Fanari, Mauro Cornacchia, Massimo Scacchi, Stefania Mai, Patrizia Ferronato, Gianfranco Parati, Cecilia Invitti
OBJECTIVE: Some cases of pseudopheochromocytoma have been described among hypertensive patients with obstructive sleep apnea (OSA). This study examined whether a pathological rise of urinary metanephrines is a common feature in hypertensive OSA patients and, in such a case, whether the ventilation treatment during sleep (continuous or biphasic positive airway pressure) may normalize high metanephrines levels. METHODS: Patients with endocrine diseases, drug abuse, therapy with TCA and cardiovascular events in the previous 6 months were excluded...
August 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28798255/benefits-of-oxytocin-administration-in-obstructive-sleep-apnea
#7
Vivek Jain, Joseph Marbach, Shawn Kimbro, David C Andrade, Arad Jain, Eleanor Capozzi, Kyle Mele, Rodrigo Del Rio, Matthew W Kay, David Mendelowitz
Activation of oxytocin receptors has shown benefits in animal models of Obstructive Sleep Apnea (OSA). We tested if nocturnal oxytocin administration could have beneficial effects in OSA patients. 8 patients diagnosed with OSA were administered intranasal oxytocin (40 i.u.). Changes in cardiorespiratory events during sleep, including apnea and hypopnea durations and frequency, risk of event-associated arousals, and heart rate variability were assessed. Oxytocin significantly increased indices of parasympathetic activity, including heart rate variability, total sleep time, and the Post-Polysommogram Sleep Assessment (PPSA) score, an index of self-reported sleep satisfaction...
August 10, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28796077/association-of-adiponectin-level-and-obstructive-sleep-apnea-prevalence-in-obese-subjects
#8
Fanfang Zeng, Xiang Wang, Wei Hu, Lili Wang
Obstructive sleep apnea (OSA) is prevalent in obese subjects. Plasma adiponectin level in obese subjects is decreased. Whether reduced adiponectin level is associated with OSA is unknown. Participants without a previous diagnosis of OSA or who have not been treated with continuous positive airway pressure were enrolled and parameters of interest were collected. Polysomnography was performed to evaluate the presence of OSA and the severity of OSA as indexed by the apnea-hypopnea index (AHI). Between-group differences were analyzed...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28795409/upper-airway-surgery-for-obstructive-sleep-apnea-reduces-blood-pressure
#9
Kenny P Pang, Edward B Pang, Kathleen A Pang, Claudio Vicini, Yiong Huak Chan, Brian W Rotenberg
OBJECTIVES/HYPOTHESIS: To evaluate if upper airway surgery reduces blood pressure in patients with obstructive sleep apnea (OSA). STUDY DESIGN: Prospective series. METHODS: A prospective series of 112 consecutive OSA patients with hypertension (HTN). All patients were > 18 years old, respiratory disturbance index >5, all levels of apnea-hypopnea index (AHI), with a history of HTN treated with medication for at least 6 months. Surgical procedures included septoplasty, turbinate reduction, palate surgery, and tongue base reduction...
August 10, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28791819/decreased-sl-selectin-serum-levels-in-sleep-apnea-syndrome-patients-with-cardiovascular-diseases
#10
Monika Kosacka, Irena Porębska, Renata Jankowska
BACKGROUND: Obstructive sleep apnea syndrome (OSA) is a common disorder associated with an increased risk of cardiovascular diseases. OBJECTIVES: sL-selectin is an adhesion molecule released from the surface of leukocytes as they are activated and may inhibit leukocyte attachment to the endothelium. The aim of this study was to evaluate sL-selectin serum levels in OSA patients with cardiovascular diseases. MATERIAL AND METHODS: A total of 163 OSA patients were enrolled in the study...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28777182/driving-safety-and-fitness-to-drive-in-sleep-disorders
#11
Jon Tippin, Mark Eric Dyken
Driving an automobile while sleepy increases the risk of crash-related injury and death. Neurologists see patients with sleepiness due to obstructive sleep apnea, narcolepsy, and a wide variety of neurologic disorders. When addressing fitness to drive, the physician must weigh patient and societal health risks and regional legal mandates. The Driver Fitness Medical Guidelines published by the National Highway Traffic Safety Administration (NHTSA) and the American Association of Motor Vehicle Administrators (AAMVA) provide assistance to clinicians...
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28762916/-predictors-of-electrical-myocardial-instability-in-men-with-arterial-hypertension-and-obstructive-sleep-apnea-hypopnea-syndrome
#12
O V Lyshova, N V Borodin, I I Kostenko
OBJECTIVE: To access the detectability of corrected QT interval (QTc) prolongation ( more or equal 450 ms) and increased QT dispersion (QTd more or equal 60 ms) in men with obstructive sleep apnea-hypopnea syndrome (OSAS) and newly diagnosed arterial hypertension (AH). MATERIAL AND METHODS: We included in this study 138 men (mean age 40.5+/-6.9 years, body mass index 34.5+/-4.7 kg/m2, all with more or equal 3 risk factors of AH development, 34% with subclinical target organs damage)...
May 2017: Kardiologiia
https://www.readbyqxmd.com/read/28760194/a-comparison-of-uvulopalatopharyngoplasty-and-modified-radiofrequency-tissue-ablation-in-mild-to-moderate-obstructive-sleep-apnea-a-randomized-clinical-trial
#13
Amin Amali, Maziar Motiee-Langroudi, Babak Saedi, Sara Rahavi-Ezabadi, Ali Karimian, Behrooz Amirzargar
STUDY OBJECTIVES: To compare the efficacy of modified radiofrequency tissue ablation (MRFTA) with uvulopalatopharyngoplasty (UPPP) based on both subjective and objective outcome measures in patients with mild to moderate obstructive sleep apnea (OSA). METHODS: Forty patients with mild to moderate OSA were randomly divided into UPPP and MRFTA groups. Evaluation was made based on the apnea-hypopnea index (AHI), Sleep Apnea Quality of Life Index (SAQLI) and Epworth Sleepiness Scale (ESS), immediately before the surgery and 6 months postoperatively...
July 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28760191/does-sleep-endoscopy-staging-pattern-correlate-with-outcome-of-advancedpalatopharyngoplasty-for-moderate-to-severe-obstructive-sleep-apnea
#14
Ying-Shuo Hsu, Ofer Jacobowitz
STUDY OBJECTIVES: Although drug-induced sleep endoscopy (DISE) is an accepted method to localize upper airway obstruction, it is not known whether allsites identified by DISE must be treated to achieve sufficient apnea-hypopnea index (AHI) improvement. The aim of this study was to compare outcomes forunilevel (upper) versus multilevel DISE collapse patterns in a patient cohort that only underwent modern palatopharyngoplasty. Our hypothesis was that notall tongue base-level obstructions on DISE must be treated...
July 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28760190/independent-contributions-of-obstructive-sleep-apnea-and-the-metabolicsyndrome-to-the-risk-of-chronic-kidney-disease
#15
Yu-Ji Lee, Hye Ryoun Jang, Wooseong Huh, Yoon-Goo Kim, Dae Joong Kim, Ha Young Oh, Eun Yeon Joo, Jung Eun Lee
STUDY OBJECTIVES: This retrospective study was conducted to evaluate the associations and interactions among obstructive sleep apnea (OSA), chronickidney disease (CKD), and metabolic syndrome (MS). METHODS: This study included 1,732 subjects (1,482 male and 250 female) in whom OSA was diagnosed by polysomnography. The severity of OSA wasdefined as mild, moderate, or severe with an apnea-hypopnea index (AHI) score of 5-15, 15-30, and ≥ 30 events/h, respectively...
July 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28759260/nocturnal-oximetry-based-evaluation-of-habitually-snoring-children
#16
Roberto Hornero, Leila Kheirandish-Gozal, Gonzalo C Gutiérrez-Tobal, Mona F Philby, María Luz Alonso-Álvarez, Daniel Álvarez, Ehab A Dayyat, Zhifei Xu, Yu-Shu Huang, Maximiliano Tamae Kakazu, Albert M Li, Annelies Van Eyck, Pablo E Brockmann, Zarmina Ehsan, Narong Simakajornboon, Athanasios G Kaditis, Fernando Vaquerizo-Villar, Andrea Crespo Sedano, Oscar Sans Capdevila, Magnus von Lukowicz, Joaquín Terán-Santos, Félix Del Campo, Christian F Poets, Rosario Ferreira, Katalina Bertran, Yamei Zhang, John Schuen, Stijn Verhulst, David Gozal
BACKGROUND: The vast majority of children around the world undergoing adenotonsillectomy for obstructive sleep apnea-hypopnea syndrome (OSA) are not objectively diagnosed with nocturnal polysomnography (NPSG) due to access availability and cost issues. Automated analysis of nocturnal oximetry (nSpO2), which is readily and globally available, could potentially provide a reliable and convenient diagnostic approach for pediatric OSA. METHODS: De-identified nSpO2 recordings from a total of 4,191 children originating from 13 pediatric sleep laboratories around the world were prospectively evaluated after developing and validating an automated neural network algorithm using an initial set of single-channel nSpO2 recordings from 589 patients referred for suspected OSA...
July 31, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28757513/validation-of-a-sheet-shaped-body-vibrometer-for-screening-of-obstructive-sleep-apnea
#17
Takamasa Kogure, Mina Kobayashi, Takashi Okawa, Tsuneya Nakajima, Yuichi Inoue
We assessed the validity of using a sheet-shaped body vibrometer (SBV) as a portable monitoring device for obstructive sleep apnea (OSA) screening. Seventy consecutive patients with suspected OSA underwent simultaneous in-laboratory polysomnography (PSG) and SBV. We evaluated the screening accuracy of the respiratory event index (REI) obtained with the SBV, using the REI based on either the estimated total sleep time (REI_eTST) or time in bed (REI_TIB); these were compared to the apnea-hypopnea index (AHI) obtained via PSG...
2017: Drug Discoveries & Therapeutics
https://www.readbyqxmd.com/read/28751184/restoration-of-sleep-architecture-after-maxillomandibular-advancement-success-beyond-the-apnea-hypopnea-index
#18
S Y-C Liu, L-K Huon, C Ruoff, R W Riley, K P Strohl, Z Peng
While effects of maxillomandibular advancement (MMA) on respiratory parameters for patients with obstructive sleep apnea (OSA) are well described, effects on sleep architecture before and after MMA are not. A retrospective cohort analysis on sleep architecture was examined in 10 OSA patients who underwent MMA surgery between July 2013 and November 2014, and had prespecified complete polysomnography (PSG) datasets. Sleep stages were examined relative to a Western European population-based control group. All of the respiratory parameters improved significantly post MMA...
July 24, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28749983/how-does-mandibular-advancement-with-or-without-maxillary-procedures-affect-pharyngeal-airways-an-overview-of-systematic-reviews
#19
Su Keng Tan, Wai Keung Leung, Alexander Tin Hong Tang, Roger A Zwahlen
BACKGROUND: Mandibular advancement surgery may positively affect pharyngeal airways and therefore potentially beneficial to obstructive sleep apnea (OSA). OBJECTIVE: To collect evidence from published systematic reviews that have evaluated pharyngeal airway changes related to mandibular advancement with or without maxillary procedures. METHODOLOGY: PubMed, EMBASE, Web of Science, and Cochrane Library were searched without limiting language or timeline...
2017: PloS One
https://www.readbyqxmd.com/read/28745298/gender-differences-in-severity-of-desaturation-events-following-hypopnea-and-obstructive-apnea-events-in-adults-during-sleep
#20
Antti Kulkas, Brett Duce, Timo Leppänen, Craig Hukins, Juha Töyräs
OBJECTIVE: Severity estimation of obstructive sleep apnea (OSA) is currently based on the apnea-hypopnea index (AHI), which ignores individual breathing cessation event characteristics. Gender differences in the relationship between the breathing cessation event duration and the related desaturation event severity could mean that the severity of OSA is different in males and females despite a similar AHI. The aim of this work was to evaluate gender differences in the severity of peripheral oxygen desaturation events following obstructive apneas or hypopneas...
July 26, 2017: Physiological Measurement
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