Salman M Toor, Eman K Aldous, Aijaz Parray, Naveed Akhtar, Yasser Al-Sarraj, Essam M Abdelalim, Abdelilah Arredouani, Omar El-Agnaf, Paul J Thornalley, Sajitha V Pananchikkal, Ghulam Jeelani Pir, Raheem Ayadathil, Ashfaq Shuaib, Nehad M Alajez, Omar M E Albagha
Transient ischemic attack (TIA) refers to a momentary neurologic deficit caused by focal cerebral, spinal or retinal ischemic insult. TIA is associated with a high risk of impending acute ischemic stroke (AIS), a neurologic dysfunction characterized by focal cerebral, spinal or retinal infarction. Understanding the differences in molecular pathways in AIS and TIA has merit for deciphering the underlying cause for neuronal deficits with long-term effects and high risks of morbidity and mortality. In this study, we performed comprehensive investigations into the circulating microRNA (miRNA) profiles of AIS ( n = 191) and TIA ( n = 61) patients...
December 21, 2022: International Journal of Molecular Sciences