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Breast tomosynthesis

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https://www.readbyqxmd.com/read/28214227/automated-breast-density-computation-in-digital-mammography-and-digital-breast-tomosynthesis-influence-on-mean-glandular-dose-and-birads-density-categorization
#1
Maria Castillo-García, Margarita Chevalier, Julia Garayoa, Alejandro Rodriguez-Ruiz, Diego García-Pinto, Julio Valverde
RATIONALE AND OBJECTIVES: The study aimed to compare the breast density estimates from two algorithms on full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) and to analyze the clinical implications. MATERIALS AND METHODS: We selected 561 FFDM and DBT examinations from patients without breast pathologies. Two versions of a commercial software (Quantra 2D and Quantra 3D) calculated the volumetric breast density automatically in FFDM and DBT, respectively...
February 14, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28211806/digital-breast-tomosynthesis-plus-mammography-magnetic-resonance-imaging-plus-mammography-and-mammography-alone-a-comparison-of-diagnostic-performance-in-symptomatic-women
#2
Wei Tang, Fei-Xiang Hu, Hui Zhu, Qi-Feng Wang, Ya-Jia Gu, Wei-Jun Peng
PURPOSE: To compare the diagnostic efficiency of digital breast tomosynthesis (DBT) plus digital mammography (DM) and magnetic resonance imaging (MRI) plus DM in symptomatic women. MATERIALS AND METHODS: The protocol used in our study was accepted by the ethics committee at our hospital, and informed consent was obtained from all patients. Between June and December 2014, 197 patients with 238 histologically proven lesions all underwent DM, DBT and MRI. Two radiologists were responsible for interpreting all images according to the Breast Imaging Reporting and Data System (BI-RADS)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28192742/breast-cancer-detection-using-single-reading-of-breast-tomosynthesis-3d-mammography-compared-to-double-reading-of-2d-mammography-evidence-from-a-population-based-trial
#3
Nehmat Houssami, Daniela Bernardi, Marco Pellegrini, Marvi Valentini, Carmine Fantò, Livio Ostillio, Paolina Tuttobene, Andrea Luparia, Petra Macaskill
BACKGROUND: Most population breast cancer (BC) screening programs use double-reading of 2D-mammography. We recently reported the screening with tomosynthesis or standard mammography-2 (STORM-2) trial, showing that double-read tomosynthesis (pseudo-3D-mammography) detected more BC than double-read 2D-mammography. In this study, we compare screen-detection measures for single-reading of 3D-mammography with those for double-reading of 2D-mammography, to inform screening practice. METHODS: This is a secondary analysis based on STORM-2 which prospectively compared 3D-mammography and 2D-mammography in sequential screen-readings...
February 10, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28188043/digital-breast-tomosynthesis-practice-patterns-following-2011-fda-approval-a-survey-of-breast-imaging-radiologists
#4
Yiming Gao, James S Babb, Hildegard K Toth, Linda Moy, Samantha L Heller
RATIONALE AND OBJECTIVES: To evaluate uptake, patterns of use, and perception of digital breast tomosynthesis (DBT) among practicing breast radiologists. MATERIALS AND METHODS: Institutional Review Board exemption was obtained for this Health Insurance Portability and Accountability Act-compliant electronic survey, sent to 7023 breast radiologists identified via the Radiological Society of North America database. Respondents were asked of their geographic location and practice type...
February 7, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28177646/digital-breast-tomosynthesis-cost-effectiveness-of-using-private-and-medicare-insurance-in-community-based-health-care-facilities
#5
Sara A Hunter, Colleen Morris, Karl Nelson, Brandon J Snyder, Thomas B Poulton
OBJECTIVE: The purpose of this study was to determine whether digital breast tomosynthesis (DBT) is a cost-effective alternative to full-field digital mammography (FFDM) for both Medicare and privately insured patients undergoing screening mammography. MATERIALS AND METHODS: A retrospective data analysis was performed between July 15, 2013, and July 14, 2014, with data on women presenting for screening mammography that included any additional radiologic workup (n = 6319)...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28151728/optimization-of-digital-breast-tomosynthesis-dbt-acquisition-parameters-for-human-observers-effect-of-reconstruction-algorithms
#6
Rongping Zeng, Aldo Badano, Kyle Myers
We showed in our earlier work that the choice of reconstruction methods does not affect the optimization of DBT acquisition parameters (angular span and number of views) using simulated breast phantom images in detecting lesions with a channelized Hoteling observer (CHO). In this work we investigate whether the model-observer based conclusion is valid when using humans to interpret images. We used previously generated DBT breast phantom images and recruited human readers to find the optimal geometry settings associated with two reconstruction algorithms, filtered back projection (FBP) and simultaneous algebraic reconstruction technique (SART)...
February 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28151431/characterisation-of-noise-and-sharpness-of-images-from-four-digital-breast-tomosynthesis-systems-for-simulation-of-images-for-virtual-clinical-trials
#7
Alistair Mackenzie, Nicholas Marshall, Andria Hadjipanteli, David Dance, Hilde Bosmans, Kenneth Young
In-depth evaluation of the noise and sharpness characteristics of FujiFilm Innovality, GE SenoClaire, Hologic Selenia Dimensions and Siemens Inspiration digital breast tomosynthesis (DBT) systems was performed with the intention of improving image simulation for virtual clinical trials. Noise power spectra (NPS) and modulation transfer function curves (MTF) were measured for planar modes and for the first and central projections for DBT modes. In DBT mode, the x-ray beam was blocked for the projections before the central projection in order to remove the influence of lag and ghosting from the previous images...
February 2, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28141582/radiation-shielding-calculation-for-digital-breast-tomosynthesis-rooms-with-an-updated-workload-survey
#8
Kai Yang, Thomas J Schultz, Xinhua Li, Bob Liu
PURPOSE: To present shielding calculations for clinical digital breast tomosynthesis (DBT) rooms with updated workload data from a comprehensive survey and to provide reference shielding data for DBT rooms. METHODS: The workload survey was performed from eight clinical DBT (Hologic Selenia Dimensions) rooms at Massachusetts General Hospital (MGH) for the time period between 10/1/2014 and 10/1/2015. Radiation output related information tags from the DICOM header, including mAs, kVp, beam filter material and gantry angle, were extracted from a total of 310 421 clinical DBT acquisitions from the PACS database...
January 31, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28139412/value-analysis-of-digital-breast-tomosynthesis-for-breast-cancer-screening-in-a-us-medicaid-population
#9
Jeffrey D Miller, Machaon M Bonafede, Sally D Herschorn, Scott K Pohlman, Kathleen A Troeger, Laurie L Fajardo
PURPOSE: Better understanding regarding the clinical-economic value of digital breast tomosynthesis (DBT) for breast cancer screening for Medicaid enrollees is needed to help inform sound, value-based decision making. The objective of this study was to conduct a clinical-economic value analysis of DBT for breast cancer screening among women enrolled in Medicaid to assess the potential clinical benefits, associated expenditures, and net budget impact of DBT. METHODS: Two annual screening mammography scenarios were evaluated with an economic model: (1) full-field digital mammography and (2) combined full-field digital mammography and DBT...
January 26, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28121523/agreement-between-breast-percentage-density-estimations-from-standard-dose-versus-synthetic-digital-mammograms-results-from-a-large-screening-cohort-using-automated-measures
#10
Emily F Conant, Brad M Keller, Lauren Pantalone, Aimilia Gastounioti, Elizabeth S McDonald, Despina Kontos
Purpose To evaluate agreement between automated estimates of breast density made from standard-dose versus synthetic digital mammograms in a large cohort of women undergoing screening. Materials and Methods This study received institutional review board approval with waiver of consent. A total of 3668 negative (Breast Imaging Reporting and Data System category 1 or 2) digital breast tomosynthesis (DBT) screening examinations consecutively performed over a 4-month period at one institution for which both standard-dose and synthetic mammograms were available for analysis were retrospectively analyzed...
January 25, 2017: Radiology
https://www.readbyqxmd.com/read/28114105/model-observer-design-for-multi-signal-detection-in-the-presence-of-anatomical-noise
#11
Gezheng Wen, Mia K Markey, Subok Park
As psychophysical studies are resource-intensive to conduct, model observers are commonly used to assess and optimize medical imaging quality. Model observers are typically designed to detect at most one signal. However, in clinical practice, there may be multiple abnormalities in a single image set (e.g. multifocal multicentric (MFMC) breast cancer), which can impact treatment planning. Prevalence of signals can be different across anatomical regions, and human observers do not know the number or location of signals a priori...
February 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28112559/breast-radiation-dose-with-cesm-compared-with-2d-ffdm-and-3d-tomosynthesis-mammography
#12
Judy R James, William Pavlicek, James A Hanson, Thomas F Boltz, Bhavika K Patel
OBJECTIVE: We aimed to compare radiation dose received during contrast-enhanced spectral mammography (CESM) using high- and low-energy projections with radiation dose received during 2D full field digital mammography (FFDM) and 3D tomosynthesis on phantoms and patients with varying breast thickness and density. MATERIALS AND METHODS: A single left craniocaudal projection was chosen to determine the doses for 6214 patients who underwent 2D FFDM, 3662 patients who underwent 3D tomosynthesis, and 173 patients who underwent CESM in this retrospective study...
February 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28107735/breast-cancers-detected-in-only-one-of-two-arms-of-a-tomosynthesis-3d-mammography-population-screening-trial-storm-2
#13
Daniela Bernardi, Nehmat Houssami
The prospective 'screening with tomosynthesis or standard mammography-2 (STORM-2)' trial compared mammography screen-reading strategies and showed that each of integrated 2D/3D-mammography or 2Dsynthetic/3D-mammography detected significantly more breast cancers than 2D-mammography alone. This short report describes 13 (from 90) cancers detected in only one of two parallel double-reading arms implemented in STORM-2. Amongst this subset of cases, the majority was invasive cancer ≤16 mm, mostly depicted as irregular masses or distortions...
January 17, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28104031/-value-of-digital-breast-tomosynthesis-dbt-in-the-diagnosis-of-breast-lesions
#14
L Yang, J Li, C W Zhou
Objective: To assess the value of digital breast tomosynthesis (DBT) in the diagnosis of breast lesions. Methods: Two hundred and fifty-three breast lesions in 250 patients were selected in this study. All lesions were confirmed pathologically. Preoperative diagnosis was performed independently with full-field digital mammography (FFDM), DBT and DBT plus FFDM, respectively. The diagnostic value of DBT for breast lesions was evaluated based on the pathological diagnosis as the gold standard. The diagnostic performance of DBT and FFDM for breast lesions was compared between the groups with different ages, mammary gland densities and hormone levels...
January 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28097214/location-and-lesion-dependent-estimation-of-mammographic-background-tissue-complexity
#15
Ali Avanaki, Kathryn Espig, Tom Kimpe
We specify a notion of perceived background tissue complexity (BTC) that varies with lesion shape, lesion size, and lesion location in the image. We propose four unsupervised BTC estimators based on: perceived pre and postlesion similarity of images, lesion border analysis (LBA; conspicuous lesion should be brighter than its surround), tissue anomaly detection, and local energy. The latter two are existing methods adapted for location- and lesion-dependent BTC estimation. For evaluation, we ask human observers to measure BTC (threshold visibility amplitude of a given lesion inserted) at specified locations in a mammogram...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28081006/latent-feature-representation-with-depth-directional-long-term-recurrent-learning-for-breast-masses-in-digital-breast-tomosynthesis
#16
Dae Hoe Kim, Seong Tae Kim, Jung Min Chang, Yong Man Ro
Characterization of masses in computer-aided detection systems for digital breast tomosynthesis (DBT) is an important step to reduce false positive (FP) rates. To effectively differentiate masses from FPs in DBT, discriminative mass feature representation is required. In this paper, we propose a new latent feature representation boosted by depth directional long-term recurrent learning for characterizing malignant masses. The proposed network is designed to encode mass characteristics in two parts. First, 2D spatial image characteristics of DBT slices are encoded as a slice feature representation by convolutional neural network (CNN)...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28075622/imaging-surveillance-after-primary-breast-cancer-treatment
#17
Diana L Lam, Nehmat Houssami, Janie M Lee
OBJECTIVE: Current clinical guidelines are consistent in supporting annual mammography for women after treatment of primary breast cancer. Surveillance imaging beyond standard digital mammography, including digital breast tomosynthesis (DBT), breast ultrasound, and MRI, may improve outcomes. This article reviews the evidence on the performance and effectiveness of breast imaging modalities available for surveillance after treatment of sporadic unilateral primary breast cancer and identifies additional factors to be considered when selecting an imaging surveillance regimen...
January 11, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28075335/towards-standardization-of-x-ray-beam-filters-in-digital-mammography-and-digital-breast-tomosynthesis-monte-carlo-simulations-and-analytical-modelling
#18
Suman Shrestha, Srinivasan Vedantham, Andrew Karellas
In digital breast tomosynthesis and digital mammography, the x-ray beam filter material and thickness vary between systems. Replacing K-edge filters with Al was investigated with the intent to reduce exposure duration and to simplify system design. Tungsten target x-ray spectra were simulated with K-edge filters (50 µm Rh; 50 µm Ag) and Al filters of varying thickness. Monte Carlo simulations were conducted to quantify the x-ray scatter from various filters alone, scatter-to-primary ratio (SPR) with compressed breasts, and to determine the radiation dose to the breast...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28072582/the-effect-of-system-geometry-and-dose-on-the-threshold-detectable-calcification-diameter-in-2d-mammography-and-digital-breast-tomosynthesis
#19
Andria Hadjipanteli, Premkumar Elangovan, Alistair Mackenzie, Padraig T Looney, Kevin Wells, David R Dance, Kenneth C Young
Digital breast tomosynthesis (DBT) is under consideration to replace or to be used in combination with 2D-mammography in breast screening. The aim of this study was the comparison of the detection of microcalcification clusters by human observers in simulated breast images using 2D-mammography, narrow angle (15°/15 projections) and wide angle (50°/25 projections) DBT. The effects of the cluster height in the breast and the dose to the breast on calcification detection were also tested. Simulated images of 6 cm thick compressed breasts were produced with and without microcalcification clusters inserted, using a set of image modelling tools for 2D-mammography and DBT...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28072573/design-and-application-of-a-structured-phantom-for-detection-performance-comparison-between-breast-tomosynthesis-and-digital-mammography
#20
L Cockmartin, N W Marshall, G Zhang, K Lemmens, E Shaheen, C Van Ongeval, E Fredenberg, D R Dance, E Salvagnini, K Michielsen, H Bosmans
This paper introduces and applies a structured phantom with inserted target objects for the comparison of detection performance of digital breast tomosynthesis (DBT) against 2D full field digital mammography (FFDM). The phantom consists of a 48 mm thick breast-shaped polymethyl methacrylate (PMMA) container filled with water and PMMA spheres of different diameters. Three-dimensionally (3D) printed spiculated masses (diameter range: 3.8-9.7 mm) and non-spiculated masses (1.6-6.2 mm) along with microcalcifications (90-250 µm) were inserted as targets...
January 10, 2017: Physics in Medicine and Biology
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