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Breast tomosynthesis

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https://www.readbyqxmd.com/read/29451022/breast-tomosynthesis-for-the-clarification-of-mammographic-bi-rads-3-lesions-can-decrease-follow-up-examinations-and-enables-immediate-cancer-diagnosis
#1
Sonja D Bahrs, Vanessa Otto, Valerie Hattermann, Bernhard Klumpp, Markus Hahn, Konstantin Nikolaou, Katja Siegmann-Luz
Background The limited sensitivity of mammography in case of a high breast density often produces unclear or false-positive findings, so-called BI-RADS 3 lesions, which have to be followed up to prove benignity. Digital breast tomosynthesis (DBT) was developed to reduce such summation effects. Purpose To evaluate the influence of an additional DBT on the management of mammographic BI-RADS 3 findings and whether DBT can decrease the time to definitive diagnosis or not. Material and Methods We analyzed 87 patients with a mammographic non-calcified BI-RADS 3 lesion who underwent an additional DBT of the affected breast...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29430472/phantom-based-study-exploring-the-effects-of-different-scatter-correction-approaches-on-the-reconstructed-images-generated-by-contrast-enhanced-stationary-digital-breast-tomosynthesis
#2
Connor Puett, Christina Inscoe, Yueh Z Lee, Otto Zhou, Jianping Lu
Stationary digital breast tomosynthesis (sDBT) is an emerging technology in which the single rotating x-ray tube is replaced by a fixed array of multiple carbon nanotube-enabled sources, providing a higher spatial and temporal resolution. As such, sDBT offers a promising platform for contrast-enhanced (CE) imaging. However, given the minimal enhancement above background with standard operational tube settings and iodine dosing, CE breast imaging requires additional acquisition steps to isolate the iodine signal, using either temporal or dual energy subtraction (TS or DES) protocols...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29429017/performance-of-breast-cancer-screening-using-digital-breast-tomosynthesis-results-from-the-prospective-population-based-oslo-tomosynthesis-screening-trial
#3
Per Skaane, Sofie Sebuødegård, Andriy I Bandos, David Gur, Bjørn Helge Østerås, Randi Gullien, Solveig Hofvind
PURPOSE: Digital breast tomosynthesis (DBT) has the potential to overcome limitations of conventional mammography. This study investigated the effects of addition of DBT on interval and detected cancers in population-based screening. METHODS: Oslo Tomosynthesis Screening Trial (OTST) was a prospective, independent double-reading trial inviting women 50-69 years biennially, comparing full-field digital mammography (FFDM) plus DBT with FFDM alone. Performance indicators and characteristics of screen-detected and interval cancers were compared with two previous FFDM rounds...
February 10, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29427198/can-the-synthetic-c-view-images-be-used-in-isolation-for-diagnosing-breast-malignancy-without-reviewing-the-entire-digital-breast-tomosynthesis-data-set
#4
Mark C Murphy, Louise Coffey, Ailbhe C O'Neill, Cecily Quinn, Ruth Prichard, Sorcha McNally
AIMS AND OBJECTIVES: The aim of this study was to determine if the synthetic C view acquired at digital breast tomosynthesis (DBT) would give adequate information to confirm a malignancy and could obviate the need to review all the tomosynthesis image data set. METHODS: All patients with biopsy-proven breast cancer recalled from screening mammograms between May and September 2016 were included for review. For each patient, the screening 2D mammogram, the synthetic C view, and the DBT images were reviewed by three breast radiologists and each assigned a BIRADS code...
February 9, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29426360/not-all-false-positive-diagnoses-are-equal-on-the-prognostic-implications-of-false-positive-diagnoses-made-in-breast-mri-versus-in-mammography-digital-tomosynthesis-screening
#5
Christiane K Kuhl, Annika Keulers, Kevin Strobel, Hannah Schneider, Nadine Gaisa, Simone Schrading
BACKGROUND: Breast magnetic resonance imaging (MRI) has been reported to frequently result in false-positive diagnoses, limiting its positive predictive value (PPV). However, for PPV calculation, all nonmalignant tissue changes are equally considered false-positive, although the respective prognostic importance, and thus patient management implications, of different pathologies may well differ. We investigated the pathology of false-positive diagnoses made by MRI compared with radiographic (digital mammography/tomosynthesis [DM/DBT]) screening...
February 9, 2018: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/29415806/role-of-tomosynthesis-in-breast-imaging-going-forward
#6
REVIEW
M J Michell, B Batohi
Digital breast tomosynthesis (DBT) is a modified mammographic technique that overcomes some of the limitations of full-field digital mammography (2DDM) by eliminating the effect of overlapping breast tissue. In the UK, DBT is utilised in both the symptomatic setting and in breast screening assessment clinics. A literature search was conducted from 2010-2017 to ensure that the most recent developments in DBT technology, clinical applications, and assessment of its usefulness in breast screening were reviewed...
February 5, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29410346/pathologic-upgrade-rates-of-high-risk-breast-lesions-on-digital-2-dimensional-vs-tomosynthesis-mammography
#7
Leslie R Lamb, Manisha Bahl, Kevin S Hughes, Constance D Lehman
BACKGROUND: To compare the pathologic upgrade rates of high-risk breast lesions (HRLs) on digital 2D mammography (DM) versus digital breast tomosynthesis (DBT). STUDY DESIGN: The study cohort was composed of patients with HRLs diagnosed by image-guided core needle biopsy from December 2007 to February 2011 (DM group, before DBT integration) and from January 2013 to March 2016 (DBT group, after complete DBT integration). Medical records were reviewed for surgical outcomes and follow-up imaging...
February 1, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29395801/synthesized-mammography-the-new-standard-of-care-when-screening-for-breast-cancer-with-digital-breast-tomosynthesis
#8
Emily B Ambinder, Susan C Harvey, Babita Panigrahi, Ximin Li, Ryan W Woods
RATIONALE AND OBJECTIVES: This study aims to evaluate the screening performance of digital breast tomosynthesis (DBT) combined with synthesized mammography (SM) vs combined with full-field digital mammography (FFDM). MATERIALS AND METHODS: We retrospectively reviewed all screening studies utilizing FFDM + DBT (n = 7845) and SM + DBT (n = 14,776) between April 1, 2013, and February 15, 2016. Recall rate, biopsy rate, positive predictive value 1 (PPV1), positive predictive value 3 (PPV3), and cancer detection rate (CDR) were compared between the two groups...
January 25, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29390228/multiple-angulated-mammography-reconstructions-in-digital-breast-tomosynthesis-for-the-diagnosis-of-microcalcifications-added-value-to-standard-stack-reconstructions-and-synthesized-mammography
#9
Jakob Neubauer, Claudia Neubauer, Julia Wicklein, Thomas Mertelmeier, Marisa Windfuhr-Blum, Mathias Langer
PURPOSE:  To compare ratings regarding the depiction, diagnostic accuracy and lesion characterization of conventional synthesized mammography (SM), multiple angulated mammography reconstructions (INSIGHT3D), and standard stack reconstructions in digital breast tomosynthesis for microcalcifications. MATERIALS AND METHODS:  This is a retrospective, multicase, multireader study. We included patients with digital breast tomosynthesis (DBT), microcalcifications and histology over a period of four months in our institution and the same number of normal cases...
February 1, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29376838/model-observer-for-assessing-digital-breast-tomosynthesis-for-multi-lesion-detection-in-the-presence-of-anatomical-noise
#10
Gezheng Wen, Mia K Markey, Tamara Miner Haygood, Subok Park
Model observers are widely used in task-based assessments of medical image quality. The presence of multiple abnormalities in a single set of images, such as in multifocal multicentric breast cancer (MFMC), has an immense clinical impact on treatment planning and survival outcomes. Detecting multiple breast tumors is challenging as MFMC is relatively uncommon, and human observers do not know the number or locations of tumors a priori. Digital breast tomosynthesis (DBT), in which an x-ray beam sweeps over a limited angular range across the breast, has the potential to improve the detection of multiple tumors...
January 29, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29376103/virtual-assessment-of-stereoscopic-viewing-of-digital-breast-tomosynthesis-projection-images
#11
Gezheng Wen, Ho-Chang Chang, Jacob Reinhold, Joseph Y Lo, Mia K Markey
Digital breast tomosynthesis (DBT) acquires a series of projection images from different angles as an x-ray source rotates around the breast. Such imaging geometry lends DBT naturally to stereoscopic viewing as two projection images with a reasonable separation angle can easily form a stereo pair. This simulation study assessed the efficacy of stereo viewing of DBT projection images. Three-dimensional computational breast phantoms with realistically shaped synthetic lesions were scanned by three simulated DBT systems...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29375894/screening-detected-desmoid-tumor-of-the-breast-findings-at-conventional-imaging-and-digital-breast-tomosynthesis
#12
Tatjana Samardzic, Jon Lømo, Per Skaane
Desmoid tumor of the breast is a rare benign entity that usually is mistaken for carcinoma clinically and radiologically. We report two cases of desmoid tumor of the breast detected by mammography screening using digital breast tomosynthesis (DBT). The larger tumor was detected at both full-field digital mammography (FFDM) and DBT. The smaller desmoid tumor, however, was identified only at tomosynthesis. Mammographic and ultrasonographic findings at diagnostic work-up were consistent with carcinoma of the breast...
January 2018: Acta Radiologica Open
https://www.readbyqxmd.com/read/29370106/preliminary-results-of-a-new-auxiliary-mechatronic-near-field-radar-system-to-3d-mammography-for-early-detection-of-breast-cancer
#13
Ashkan Ghanbarzadeh Dagheyan, Ali Molaei, Richard Obermeier, Andrew Westwood, Aida Martinez, Jose Angel Martinez Lorenzo
Accurate and early detection of breast cancer is of high importance, as it is directly associated with the patients' overall well-being during treatment and their chances of survival. Uncertainties in current breast imaging methods can potentially cause two main problems: (1) missing newly formed or small tumors; and (2) false alarms, which could be a source of stress for patients. A recent study at the Massachusetts General Hospital (MGH) indicates that using Digital Breast Tomosynthesis (DBT) can reduce the number of false alarms, when compared to conventional mammography...
January 25, 2018: Sensors
https://www.readbyqxmd.com/read/29355405/additional-roles-of-tomosynthesis-in-breast-imaging-guided-biopsies
#14
Benoît Mesurolle, Armelle Travade, Christine Bagard, Camille Monghal
No abstract text is available yet for this article.
February 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29328943/interval-breast-cancers-in-the-screening-with-tomosynthesis-or-standard-mammography-storm-population-based-trial
#15
Nehmat Houssami, Daniela Bernardi, Francesca Caumo, Silvia Brunelli, Carmine Fantò, Marvi Valentini, Giovanna Romanucci, Maria A Gentilini, Manuel Zorzi, Petra Macaskill
BACKGROUND & METHODS: The prospective 'screening with tomosynthesis or standard mammography' (STORM) trial recruited women participating in biennial breast screening in Italy (2011-2012), and compared sequential screen-readings based on 2D-mammography alone or based on tomosynthesis (integrated 2D/3D-mammography). The STORM trial showed that tomosynthesis screen-reading significantly increased breast cancer detection compared to 2D-mammography alone. The present study completes reporting of the trial by examining interval breast cancers ascertained at two year follow-up...
January 9, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29317038/role-of-digital-breast-tomosynthesis-in-screening-and-diagnostic-breast-imaging
#16
Stamatia Destounis
Digital breast tomosynthesis is quickly becoming the standard of care in breast cancer screening and diagnosis. Since its introduction to the clinical landscape in 2011, radiologists specializing in breast disease diagnosis around the country have made the decision to adopt the technology for both screening and diagnostic applications; with adoption growing substantially in present day. Users of the technology have attested to the benefits the technology affords, both in screening and the diagnostic evaluation of patients, through peer-reviewed publications and scientific presentations in recent years...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317035/deciphering-the-breast-density-inform-law-movement-implications-for-practice
#17
Sean D Raj, Valerie Fein-Zachary, Priscilla J Slanetz
Although dense breast tissue is a normal and routine finding on screening mammography, dense breast tissue is associated with an independent increased risk for breast cancer. It is well known that screening mammography has a decreased sensitivity for cancer detection in women with dense breasts. Over the past decade, there has been increased interest generated among patients, physicians, and legislators regarding how best to screen dense-breasted women culminating in 2009 with the passage of a breast density notification law in Connecticut...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317033/emerging-breast-imaging-technologies-on-the-horizon
#18
Srinivasan Vedantham, Andrew Karellas
Early detection of breast cancers by mammography in conjunction with adjuvant therapy has contributed to reduction in breast cancer mortality. Mammography remains the "gold-standard" for breast cancer screening but is limited by tissue superposition. Digital breast tomosynthesis and more recently, dedicated breast computed tomography have been developed to alleviate the tissue superposition problem. However, all of these modalities rely upon x-ray attenuation contrast to provide anatomical images, and there are ongoing efforts to develop and clinically translate alternative modalities...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29317032/newer-technologies-in-breast-cancer-imaging-dedicated-cone-beam-breast-computed-tomography
#19
Avice M O'Connell, Andrew Karellas, Srinivasan Vedantham, Daniel T Kawakyu-O'Connor
Dedicated breast computed tomography (CT) is the latest in a long history of breast imaging techniques dating back to the 1960s. Breast imaging is performed both for cancer screening as well as for diagnostic evaluation of symptomatic patients. Dedicated breast CT received US Food and Drug Administration approval for diagnostic use in 2015 and is slowly gaining recognition for its value in diagnostic 3-dimensional imaging of the breast, and also for injected contrast-enhanced imaging applications. Conventional mammography has known limitations in sensitivity and specificity, especially in dense breasts...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29311416/average-glandular-dose-in-paired-digital-mammography-and-digital-breast-tomosynthesis-acquisitions-in-a-population-based-screening-program-effects-of-measuring-breast-density-air-kerma-and-beam-quality
#20
Bjørn Helge Østerås, Per Skaane, Randi Gullien, Anne Catrine Tregde Martinsen
The main purpose was to compare average glandular dose (AGD) for same-compression digital mammography (DM) and digital breast tomosynthesis (DBT) acquisitions in a population based screening program, with and without breast density stratification, as determined by automatically calculated breast density (QuantraTM). Secondary, to compare AGD estimates based on measured breast density, air kerma and half value layer (HVL) to DICOM metadata based estimates. AGD was estimated for 3819 women participating in the screening trial...
January 9, 2018: Physics in Medicine and Biology
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