keyword
https://read.qxmd.com/read/38483559/consistency-of-data-reporting-in-fluid-responsiveness-studies-in-the-critically-ill-setting-the-codefire-consensus-from-the-cardiovascular-dynamic-section-of-the-european-society-of-intensive-care-medicine
#21
JOURNAL ARTICLE
Antonio Messina, Michelle S Chew, Daniele Poole, Lorenzo Calabrò, Daniel De Backer, Katia Donadello, Glenn Hernandez, Olfa Hamzaoui, Mathieu Jozwiak, Christopher Lai, Manu L N G Malbrain, Jihad Mallat, Sheyla Nainan Myatra, Laurent Muller, Gustavo Ospina-Tascon, Michael R Pinsky, Sebastian Preau, Bernd Saugel, Jean-Louis Teboul, Maurizio Cecconi, Xavier Monnet
PURPOSE: To provide consensus recommendations regarding hemodynamic data reporting in studies investigating fluid responsiveness and fluid challenge (FC) use in the intensive care unit (ICU). METHODS: The Executive Committee of the European Society of Intensive Care Medicine (ESICM) commissioned and supervised the project. A panel of 18 international experts and a methodologist identified main domains and items from a systematic literature, plus 2 ancillary domains...
March 14, 2024: Intensive Care Medicine
https://read.qxmd.com/read/38476604/granulomatous-mastitis-in-accessory-breast-tissue-a-rare-presentation-and-surgical-management
#22
Abdulwahid M Salih, Lana Rα Pshtiwan, Shaban Latif, Halkawt O Ali, Ari M Abdullah, Hiwa O Baba, Jihad Ibrahim Hama, Shko H Hassan, Marwan N Hassan, Shvan H Mohammed, Mohammed L Ahmed, Fahmi H Kakamad
Granulomatous mastitis (GM) in accessory breast tissue is rare. The present study aimed to report a rare case of GM in accessory breast tissue. A 39-year-old female patient presented with right axillary discomfort and swelling for ~5 days. On clinical examination, a tender, firm lump was detected in the right axillary region. The ultrasound showed diffuse parenchymal heterogeneity and surrounding edema in the right accessory breast associated with reactive axillary lymph nodes. Following unresponsiveness to conservative treatment, a surgical procedure was performed in the form of an excisional biopsy and the lesion was diagnosed as GM...
April 2024: Biomedical Reports
https://read.qxmd.com/read/38471833/antithrombotic-therapy-in-cerebral-cavernous-malformations-a-systematic-review-meta-analysis-and-network-meta-analysis
#23
JOURNAL ARTICLE
Basel Musmar, Hamza Salim, Jihad Abdelgadir, Samantha Spellicy, Nimer Adeeb, Ali Zomorodi, Allan Friedman, Issam Awad, Pascal M Jabbour, David M Hasan
BACKGROUND: Cerebral cavernous malformations are complex vascular anomalies in the central nervous system associated with a risk of intracranial hemorrhage. Traditional guidelines have been cautious about the use of antithrombotic therapy in this patient group, citing concerns about potential bleeding risk. However, recent research posits that antithrombotic therapy may actually be beneficial. This study aims to clarify the association between antithrombotic therapy, including antiplatelet and anticoagulant medications, and the risk of intracranial hemorrhage in patients with cerebral cavernous malformations...
March 12, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38457776/limitations-of-parenchymal-volume-analysis-for-estimating-split-renal-function-and-new-baseline-gfr-after-radical-nephrectomy
#24
JOURNAL ARTICLE
Kieran Lewis, Eran N Maina, Carlos Munoz Lopez, Nityam Rathi, Worapat Attawettayanon, Akira Kazama, Jihad Kaouk, Georges-Pascal Haber, Mohamad Eltemamy, Venkatesh Krishnamurthi, Robert Abouassaly, Christopher J Weight, Steven C Campbell
PURPOSE: Accurately predicting new baseline-glomerular-filtration rate (NBGFR) after radical nephrectomy (RN) can improve counseling about RN vs partial nephrectomy. Split-renal-function (SRF)-based models are optimal, and differential parenchymal volume analysis (PVA) is more accurate than nuclear renal scans (NRS) for this purpose. However, there is minimal data regarding the limitations of PVA. Our objective was to identify patient/tumor-related factors associated with PVA inaccuracy...
March 8, 2024: Journal of Urology
https://read.qxmd.com/read/38454748/a-comprehensive-analysis-of-litigation-in-organ-transplantation-for-allegations-of-insufficient-policy-coverage-discrimination-and-malpractice
#25
JOURNAL ARTICLE
Jacob Mago, Mihir Tandon, Naoru Koizumi, Marissa Firlie, Lauren Fang, Scott Serpico, Alejandro Chiodo Ortiz, Megumi Inoue, Patrick Raymond Baxter, Yang Yu, Monique John, Kassem-Ali Jihad Abbas, Liban Dinka, Obi Ekwenna, Meng-Hao Li, Jorge Ortiz
Introduction: Transplantation is a field with unique medical and administrative challenges that involve an equally diverse array of stakeholders. Expectantly, the litigation stemming from this field should be similarly nuanced. There is a paucity of comprehensive reviews characterizing this medicolegal landscape. Design: The Caselaw Access Project Database was used to collect official court briefs of 2053 lawsuits related to kidney, liver, heart, lung, and pancreas transplantation. A thematic analysis was undertaken to characterize grounds for litigation, defendant type, and outcomes...
March 7, 2024: Progress in Transplantation
https://read.qxmd.com/read/38451352/lack-of-syndecan-1-promotes-the-pathogenesis-of-experimental-rheumatoid-arthritis
#26
JOURNAL ARTICLE
Rosalyn Jurjus, Laura Dosh, Rima Farhat, Tatiana Daccache, Jad El Masri, Maya Ghazi, Jihad Hawi, Angelo Leone, Abdo Jurjus
Syndecan-1 (Sdc-1), a transmembrane heparan sulfate protein, is implicated in several pathophysiological processes including rheumatoid arthritis (RA). The exact role of Syndican-1 in this autoimmune disease is still undetermined. This study explores the involvement level of Sdc-1 in the development of RA in a collagen II-induced arthritis mice model. RA was induced in two mice strains (wild-type BALB/c group and Sdc-1 knockout) by collagen II. Mice underwent regular clinical observations and scoring. After sacrifice, leg biopsies were taken from mice for histological examination, using a variety of stains...
March 7, 2024: Immunogenetics
https://read.qxmd.com/read/38450248/cognitive-outcomes-following-aneurysmal-subarachnoid-hemorrhage-rehabilitation-strategies
#27
REVIEW
Jihad Abdelgadir, Justin Gelman, Lindsay Dutko, Vikram Mehta, Allan Friedman, Ali Zomorodi
Despite decreases in mortality rate, the treatment of cognitive deficits following aneurysmal subarachnoid hemorrhage (aSAH) remains a serious challenge for clinicians and survivors alike. Deficits in executive function, language, and memory prevent more than half of survivors from returning to their previous level of work and put a tremendous amount of stress on the individual and their family. New therapies are needed for survivors of aSAH in order to improve cognitive outcomes and quality of life. The aim of this review is to discuss the prevalence and contributing factors of cognitive deficits following aSAH, as well as areas for therapeutic intervention...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38449933/an-unusual-presentation-of-the-cervicobrachial-variant-of-guillain-barr%C3%A3-syndrome-in-a-32-year-old-previously-healthy-male
#28
Samar Iltaf-Mairajuddin, Raheel Muneer Ahmed Channa, Abubaker Abdul Rahman Shaffi Al Madani, Jihad Said Inshas, Jai Perkash, Syed Habib Ullah Kamran
Guillain-Barré syndrome (GBS) is a rare autoimmune disorder characterized by acute peripheral nerve demyelination. The cervicobrachial (CB) variant presents with predominant upper limb weakness and has distinct clinical features. This case report aims to detail the clinical manifestations, diagnostic methodology, treatment outcomes, and broader implications of the CB variant of GBS. This case report presents a 32-year-old male, with a rare CB type of GBS, characterized by upper limb weakness and distinctive clinical features...
February 2024: Curēus
https://read.qxmd.com/read/38447093/comparative-effectiveness-of-natalizumab-fingolimod-and-injectable-therapies-in-pediatric-onset-multiple-sclerosis-a-registry-based-study
#29
JOURNAL ARTICLE
Tim Spelman, Gabrielle Simoneau, Robert Hyde, Robert Kuhelj, Raed Alroughani, Serkan Ozakbas, Rana Karabudak, Bassem I Yamout, Samia J Khoury, Murat Terzi, Cavit Boz, Dana Horakova, Eva Kubala Havrdova, Bianca Weinstock-Guttman, Francesco Patti, Ayse Altintas, Saloua Mrabet, Riadh Gouider, Jihad Inshasi, Vahid Shaygannejad, Sara Eichau, W Luke Ward, Helmut Butzkueven
BACKGROUND AND OBJECTIVES: Patients with pediatric-onset multiple sclerosis (POMS) typically experience higher levels of inflammation with more frequent relapses, and though patients with POMS usually recover from relapses better than adults, patients with POMS reach irreversible disability at a younger age than adult-onset patients. There have been few randomized, placebo-controlled clinical trials of multiple sclerosis (MS) disease-modifying therapies (DMTs) in patients with POMS, and most available data are based on observational studies of off-label use of DMTs approved for adults...
April 9, 2024: Neurology
https://read.qxmd.com/read/38428398/loss-of-epigenetic-information-as-a-cause-of-mammalian-aging
#30
Jae-Hyun Yang, Motoshi Hayano, Patrick T Griffin, João A Amorim, Michael S Bonkowski, John K Apostolides, Elias L Salfati, Marco Blanchette, Elizabeth M Munding, Mital Bhakta, Yap Ching Chew, Wei Guo, Xiaojing Yang, Sun Maybury-Lewis, Xiao Tian, Jaime M Ross, Giuseppe Coppotelli, Margarita V Meer, Ryan Rogers-Hammond, Daniel L Vera, Yuancheng Ryan Lu, Jeffrey W Pippin, Michael L Creswell, Zhixun Dou, Caiyue Xu, Sarah J Mitchell, Abhirup Das, Brendan L O'Connell, Sachin Thakur, Alice E Kane, Qiao Su, Yasuaki Mohri, Emi K Nishimura, Laura Schaevitz, Neha Garg, Ana-Maria Balta, Meghan A Rego, Meredith Gregory-Ksander, Tatjana C Jakobs, Lei Zhong, Hiroko Wakimoto, Jihad El Andari, Dirk Grimm, Raul Mostoslavsky, Amy J Wagers, Kazuo Tsubota, Stephen J Bonasera, Carlos M Palmeira, Jonathan G Seidman, Christine E Seidman, Norman S Wolf, Jill A Kreiling, John M Sedivy, George F Murphy, Richard E Green, Benjamin A Garcia, Shelley L Berger, Philipp Oberdoerffer, Stuart J Shankland, Vadim N Gladyshev, Bruce R Ksander, Andreas R Pfenning, Luis A Rajman, David A Sinclair
No abstract text is available yet for this article.
February 29, 2024: Cell
https://read.qxmd.com/read/38420656/perioperative-complications-of-single-port-and-multi-port-robotic-radical-prostatectomy-a-single-institutional-comparison-analysis
#31
JOURNAL ARTICLE
Nicolas Soputro, Jaya Sai Chavali, Roxana Ramos-Carpinteyro, Carter D Mikesell, Adriana M Pedraza, Jihad Kaouk
BACKGROUND: Following its introduction in 2018, the Single-Port (SP) robotic platform has been increasingly utilized for various approaches of robotic radical prostatectomy (RARP). Despite the demonstrable benefits in enhancing postoperative outcomes, there has been limited evidence on its perioperative morbidity, especially when compared to the gold-standard multi-port (MP). This study sought to compare the perioperative morbidity between SP and MP-RARP. METHODS: A retrospective review was performed on 911 patients who underwent RARP between January 2015 and May 2023...
February 29, 2024: Journal of Endourology
https://read.qxmd.com/read/38420339/high-grade-burkitt-lymphoma-in-an-immunocompetent-young-patient-concomitant-gastric-and-ileal-localizations
#32
Benayad Aourarh, Jihad Boularab, Lina Belkouchi, Aziz Aourarh, Meryem Edderai
Burkitt lymphoma is a highly aggressive and rapidly growing B cell non-Hodgkin lymphoma with heterogeneous pattern of manifestations. We present a rare case of a 39-year-old immunocompetent male with double localization of Burkitt lymphoma: gastroduodenal and ileal tract. The gastric location is extremely rare, and the association with another site is unusual with only few reports in the literature. Imaging modalities play a crucial role in correct diagnosis as it can manifest as a focal mass or as segmental wall thickening...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38398699/common-and-potential-emerging-foodborne-viruses-a-comprehensive-review
#33
REVIEW
Amin N Olaimat, Asma' O Taybeh, Anas Al-Nabulsi, Murad Al-Holy, Ma'mon M Hatmal, Jihad Alzyoud, Iman Aolymat, Mahmoud H Abughoush, Hafiz Shahbaz, Anas Alzyoud, Tareq Osaili, Mutamed Ayyash, Kevin M Coombs, Richard Holley
Human viruses and viruses from animals can cause illnesses in humans after the consumption of contaminated food or water. Contamination may occur during preparation by infected food handlers, during food production because of unsuitably controlled working conditions, or following the consumption of animal-based foods contaminated by a zoonotic virus. This review discussed the recent information available on the general and clinical characteristics of viruses, viral foodborne outbreaks and control strategies to prevent the viral contamination of food products and water...
January 28, 2024: Life
https://read.qxmd.com/read/38383997/useless-hand-of-oppenheim-syndrome
#34
JOURNAL ARTICLE
Jihad Al Kharbooshi, Seth Climans
No abstract text is available yet for this article.
February 22, 2024: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/38380195/infective-endocarditis-due-to-serratia-odorifera-a-case-report-and-literature-review
#35
Muhammad Hussain, Bereket Tewoldemedhin, Muhammad Waqas, Fnu Marium, Nardos Tewoldemedhin, Siham Hussien, Miriam Michael, Jihad Slim
Serratia odorifera  from the time of its discovery in the 1970's had been considered a common colonizer of the skin with little pathogenic potential. Cases of human infections caused by S. odorifera  are relatively rare. To date, very few cases have been reported describing primarily bloodstream and urinary tract infections. We describe a patient who developed endocarditis due to S. odorifera confirmed with a transesophageal echocardiogram. The patient was treated with six weeks of antibiotics with uneventful recovery...
January 2024: Curēus
https://read.qxmd.com/read/38371045/salmonella-group-b-ileitis-mimicking-crohn-s-disease-a-case-report
#36
Bereket Tewoldemedhin, Shefali Pati, Raed Atiyat, Andre Fedida, Addi Suleiman, Yazeed Abu Ruman, Ala Muhanna, Charity Iheagwara, Maria Szabela, Jihad Slim, Jack Boghossian
Salmonellae , considered among the enteric-fever-causing pathogens, is associated with a range of human infections, including gastroenteritis, bacteremia, and osteomyelitis. Salmonella -induced mesenteric adenitis and terminal ileitis resembling acute appendicitis have been reported in the literature. Here, we present a rare case of a patient presenting with severe acute active ileitis and colitis mimicking Crohn's disease with no prior history of inflammatory bowel disease and found to have Salmonella group B bacteremia...
January 2024: Curēus
https://read.qxmd.com/read/38367850/detour2-trial-outcomes-demonstrate-clinical-utility-of-percutaneous-transmural-bypass-for-the-treatment-of-long-segment-complex-femoropopliteal-disease
#37
JOURNAL ARTICLE
Sean P Lyden, Peter A Soukas, Ajanta De, Barry Tedder, Jonathan Bowman, Jihad A Mustapha, Ehrin J Armstrong
OBJECTIVE: Percutaneous transmural arterial bypass (PTAB) using the DETOUR system aims to create a percutaneous, endovascular femoropopliteal bypass for the treatment of long segment, complex superficial femoral and proximal popliteal artery disease. The goal of the DETOUR2 study is to investigate the safety and effectiveness of the therapy in comparison with pre-established performance goals. METHODS: The DETOUR-2 investigational device exemption study is a prospective, single-arm, multicenter, international trial of symptomatic peripheral arterial disease patients (Rutherford classes 3-5) undergoing the DETOUR procedure for long segment (>20 cm) superficial femoral artery disease...
February 15, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38364532/feasibility-of-using-vertical-farming-in-northern-iran-a-multiple-necessity
#38
JOURNAL ARTICLE
Zahra Akbari, Arasto Yari Hesar, Narges Siamian, Christine Fürst, Rando Värnik, Hossein Azadi
Agricultural production in vertical farms (VF) will play a prominent role in preventing environmental crises, its good governance and maintaining food security for everyone in the world. The ecological footprint in Guilan province significantly exceeds its biological capacity, indicating considerable pressure on its natural resources and ecosystems. This problem, which is mostly due to the use of traditional production methods in the agricultural sector, requires a change in lifestyle and production methods...
February 15, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38355293/parenchymal-volume-preservation-during-partial-nephrectomy-improved-methodology-to-assess-impact-and-predictive-factors
#39
JOURNAL ARTICLE
Akira Kazama, Worapat Attawettayanon, Carlos Munoz-Lopez, Nityam Rathi, Kieran Lewis, Eran Maina, Rebecca A Campbell, Zaeem Lone, Melissa Boumitri, Jihad Kaouk, Georges-Pascal Haber, Samuel Haywood, Nima Almassi, Christopher Weight, Jianbo Li, Steven C Campbell
OBJECTIVE: To rigorously evaluate the impact of the percentage of parenchymal volume preserved (PPVP) and how well the preserved parenchyma recovers from ischaemia (Recischaemia ) on functional outcomes after partial nephrectomy (PN) using an accurate and objective software-based methodology for estimating parenchymal volumes and split renal function (SRF). A secondary objective was to assess potential predictors of the PPVP. PATIENTS AND METHODS: A total of 894 PN patients with available studies (2011-2014) were evaluated...
February 14, 2024: BJU International
https://read.qxmd.com/read/38350376/a-microsurgical-approach-to-post-traumatic-penile-amputation-towards-standardizing-the-technique-a-case-report
#40
Hamza Dergamoun, Jihad Lakssir, Aziz E L Gdaouni, Ossama Jalal, Amine Saouli, Imad Ziouziou
INTRODUCTION: Penile amputation is an unusual situation reported globally as isolated cases and small series. It constitutes a urological emergency which requires microsurgical skills for the repair of the penis. We present a case of a penile amputation and discuss the management of this challenging condition. CASE PRESENTATION: A 47-year-old patient presented to the emergency room with total amputation of corpora cavernosa of the penis resulting from knife aggression...
February 11, 2024: International Journal of Surgery Case Reports
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