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https://www.readbyqxmd.com/read/28087299/when-partial-nephrectomy-is-unsuccessful-understanding-the-reasons-for-conversion-from-robotic-partial-to-radical-nephrectomy-at-a-tertiary-referral-center
#1
Önder Kara, Matthew J Maurice, Pascal Mouracade, Ercan Malkoç, Julien Dagenais, Ryan J Nelson, Jaya Sai Chavali, Robert J Stein, Amr Fergany, Jihad H Kaouk
OBJECTIVE: To identify the preoperative factors associated with conversion from robotic partial nephrectomy (RPN) to radical nephrectomy (RN), and to report the incidence of this event. PATIENTS AND METHODS: Using our institutional review board-approved database, we abstracted data on 1023 RPN cases performed at our center between 2010 and 2015. Standard and converted cases were compared in terms of patients and tumor characteristics and perioperative, functional, and oncological outcomes...
January 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28081208/optimizing-training-population-size-and-genotyping-strategy-for-genomic-prediction-using-association-study-results-and-pedigree-information-a-case-of-study-in-advanced-wheat-breeding-lines
#2
Fabio Cericola, Ahmed Jahoor, Jihad Orabi, Jeppe R Andersen, Luc L Janss, Just Jensen
Wheat breeding programs generate a large amount of variation which cannot be completely explored because of limited phenotyping throughput. Genomic prediction (GP) has been proposed as a new tool which provides breeding values estimations without the need of phenotyping all the material produced but only a subset of it named training population (TP). However, genotyping of all the accessions under analysis is needed and, therefore, optimizing TP dimension and genotyping strategy is pivotal to implement GP in commercial breeding schemes...
2017: PloS One
https://www.readbyqxmd.com/read/28057290/inframalleolar-interventions-in-critical-limb-ischemia-trailblazing-the-path-toward-the-final-frontier
#3
EDITORIAL
Jihad A Mustapha, Fadi Saab, Larry J Diaz-Sandoval
No abstract text is available yet for this article.
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28029270/intervening-to-reduce-the-risk-of-future-disability-from-multiple-sclerosis-are-we-there-yet
#4
Maurice Dahdaleh, Raed Alroughani, Mohammed Aljumah, Abdulrahman AlTahan, Issa Alsharoqi, Saeed A Bohlega, Abdulkader Daif, Dirk Deleu, Jihad Inshasi, Rana Karabudak, Mohammed A Sahraian, Karim Taha, Bassem I Yammout, Magd Zakaria
Disease-modifying therapies (DMTs) delay or may prevent the progression of patients with high-risk clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (MS), and from relapsing-remitting MS to secondary progressive MS. Current evidence on the effects of DMT on disability in MS is supported by the use of the Expanded Disability Status Scale (EDSS), which is dominated by ambulation, and usually used as a secondary outcome measure. Less is known about the long-term effects of DMTs on other aspects of functional status, particularly cognition, which is a key determinant of ability to work...
December 28, 2016: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28017741/morphology-of-ruptured-and-unruptured-intracranial-aneurysms
#5
Tammam Abboud, Jihad Rustom, Maxim Bester, Patrick Czorlich, Eik Vittorazzi, Hans O Pinnschmidt, Manfred Westphal, Jan Regelsberger
BACKGROUND: In addition to size and location, morphology of intracranial aneurysm has been proposed to predict rupture. This study was undertaken to compare morphological features between ruptured and unruptured aneurysms and identify those associated with higher rupture risk. METHODS: Between 2010 and 2014, 301 patients with SAH and 204 with unruptuted aneurysms were admitted to our hospital. Two investigators reviewed 3-dimensional angiograms of all aneurysms...
December 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28008330/increased-levels-of-circulating-and-tumor-infiltrating-granulocytic-myeloid-cells-in-colorectal-cancer-patients
#6
Salman M Toor, Azharuddin Sajid Syed Khaja, Haytham El Salhat, Omar Bekdache, Jihad Kanbar, Mohammed Jaloudi, Eyad Elkord
Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. However, limited data are available on their conclusive phenotypes and their correlation with clinical settings. The aim of this study was to investigate levels and phenotype of myeloid cells in peripheral blood and tumor microenvironment (TME) of colorectal cancer (CRC) patients, compared to blood from healthy donors (HDs) and paired, adjacent non-tumor colon tissue...
2016: Frontiers in Immunology
https://www.readbyqxmd.com/read/27999052/trimethoprim-sulfamethoxazole-versus-vancomycin-in-the-treatment-of-healthcare-ventilator-associated-mrsa-pneumonia-a-case-control-study
#7
Noa Eliakim-Raz, Moran Hellerman, Dafna Yahav, Jonathan Cohen, Ili Margalit, Sharon Fisher, Oren Zusman, Hila Shaked, Jihad Bishara
OBJECTIVES: Therapeutic options available to treat MRSA pneumonia are limited. Trimethoprim/sulfamethoxazole is an attractive treatment because of its bactericidal anti-MRSA activity, oral and parenteral formulations and good penetration to the lung tissue. We aimed to compare the efficacy and safety of trimethoprim/sulfamethoxazole with vancomycin in the treatment of healthcare/ventilator-associated MRSA pneumonia. METHODS: We carried out a retrospective case-control study of all consecutive hospitalized adult patients diagnosed with MRSA pneumonia at Beilinson Hospital during 2010-15 and treated with either vancomycin or trimethoprim/sulfamethoxazole...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27993666/patterns-and-predictors-of-recurrence-after-partial-nephrectomy-for-kidney-tumors
#8
Pascal Mouracade, Onder Kara, Matthew J Maurice, Julien Dagenais, Ercan Malkoc, Ryan J Nelson, Jihad H Kaouk
PURPOSE: To identify patterns and predictors of recurrence in patients with clinically localized renal cell carcinoma (CLRCC) managed with partial nephrectomy (PN). MATERIALS AND METHODS: Retrospective study of 830 consecutive cases of PN done between 2007 and 2015 for CLRCC at a single institution. Patient demographics, and pathological characteristics were correlated with recurrence patterns (overall, local and distant) and overall survival (OS) using Kaplan-Meier and cox regression analyses...
December 16, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27988984/safety-and-early-effectiveness-of-robotic-partial-nephrectomy-for-large-angiomyolipomas
#9
Shay Golan, Scott Johnson, Matthew Maurice, Jihad Kaouk, Weil Lai, Benjamin Lee, Steve Kheyfets, Chandru Sundaram, David Cahn, Robert Uzzo, Arieh Shalhav
OBJECTIVES: To evaluate a multicenter series of robotic assisted partial nephrectomy (RAPN) performed for the treatment of large angiomyolipomas (AMLs). MATERIALS AND METHODS: Between 2005-2016, 40 patients with large or symptomatic AMLs underwent RAPN at 5 academic centers in the United States. Patient demographics, AML characteristics, operative and postoperative clinical outcomes were recorded and analyzed. Surgical outcomes were compared between patients who underwent selective arterial embolization (SAE) before RAPN and patients who did not undergo pre-RAPN SAE...
December 18, 2016: BJU International
https://www.readbyqxmd.com/read/27984535/modulation-by-polymyxin-b-hemoperfusion-of-inflammatory-response-related-to-severe-peritonitis
#10
Rémi Coudroy, Didier Payen, Yoann Launey, Anne-Claire Lukaszewicz, Mahmoud Kaaki, Benoit Veber, Olivier Collange, Antoine Dewitte, Laurent Martin-Lefevre, Matthieu Jabaudon, Thomas Kerforne, Martine Ferrandière, Eric Kipnis, Carlos Vela, Stéphanie Chevalier, Jihad Mallat, Sandrine Charreau, Jean-Claude Lecron, René Robert
Conflicting results have been reported on the influence of Polymyxin-B hemoperfusion treatment on systemic inflammation markers. The aim of the study was to assess in a randomized control trial the influence on plasma cytokine concentrations of Polymyxin-B hemoperfusion in septic shock due to peritonitis. A panel of 10 pro- or anti-inflammatory cytokines was measured in 213 patients with peritonitis-induced septic shock enrolled in the randomized trial ABDOMIX testing the impact of 2 Polymyxin-B hemoperfusion sessions with standard treatment...
January 2017: Shock
https://www.readbyqxmd.com/read/27970189/tct-799-comparison-of-ultrasound-guided-femoral-retrograde-versus-antegrade-access-among-patients-undergoing-peripheral-arterial-interventions
#11
Jihad Mustapha, Michael Jaff, George Adams, Larry Diaz, Robert Beasley, Sara Finton, Theresa McGoff, Carmen Heaney, Larry Miller, Fadi Saab
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970180/tct-792-non-invasive-hemodynamics-poorly-predict-disease-severity-and-response-to-endovascular-therapy-in-patients-with-critical-limb-ischemia
#12
Jihad Mustapha, Michael Jaff, George Adams, Larry Diaz, Robert Beasley, Theresa McGoff, Sara Finton, Carmen Heaney, Larry Miller, Fadi Saab
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970165/tct-778-outcomes-from-the-chocolate-bar-a-large-multi-center-prospective-post-market-study-on-use-of-the-chocolate-percutaneous-transluminal-angioplasty-pta-balloon
#13
Georgios Bouras, Alexandra Lansky, John McClure, Mehdi Shishehbor, Michael Jaff, Prakash Makam, Sarah Johnson, Thomas Davis, Jihad Mustapha
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27956465/hfq-and-three-hfq-dependent-small-regulatory-rnas-mgrr-ryhb-and-mcas-coregulate-the-locus-of-enterocyte-effacement-in-enteropathogenic-escherichia-coli
#14
Shantanu Bhatt, Marisa Egan, Jasmine Ramirez, Christian Xander, Valerie Jenkins, Sarah Muche, Jihad El-Fenej, Jamie Palmer, Elisabeth Mason, Elizabeth Storm, Thomas Buerkert
Enteropathogenic Escherichia coli (EPEC) is a significant cause of infantile diarrhea and death in developing countries. The pathogenicity island locus of enterocyte effacement (LEE) is essential for EPEC to cause diarrhea. Besides EPEC, the LEE is also present in other gastrointestinal pathogens, most notably enterohemorrhagic E. coli (EHEC). Whereas transcriptional control of the LEE has been meticulously examined, posttranscriptional regulation, including the role of Hfq-dependent small RNAs, remains undercharacterized...
February 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/27942197/hepatitis-a-vaccine-response-in-human-immunodeficiency-virus-infected-patients-the-interchangeability-of-single-dose-versus-double-a-prospective-look
#15
Jason Dazley, Raymund Sison, Humberto Jimenez, Jihad Slim
No abstract text is available yet for this article.
October 2016: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/27927035/robotic-partial-nephrectomy-for-posterior-tumors-via-a-retroperitoneal-approach-offers-decreased-length-of-stay-compared-to-the-transperitoneal-approach-a-propensity-matched-analysis
#16
Matthew Joseph Maurice, Jihad Kaouk, Daniel Ramirez, Sam Bhayani, Mohamad E Allaf, Craig G Rogers, Michael D Stifelman
INTRODUCTION: We sought to compare surgical outcomes between transperitoneal and retroperitoneal robotic partial nephrectomy (RPN) for posterior tumors. PATIENTS AND METHODS: Using our multi-institutional RPN database, we reviewed 610 consecutive cases for posterior renal masses treated between 2007-2015. Primary outcomes were complications, operative time, length of stay (LOS), surgical margin status, and eGFR preservation. Secondary outcomes were estimated blood loss, warm ischemia time (WIT), disease recurrence, and disease-specific mortality...
December 7, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27917963/mobile-pastoralists-in-central-and-west-africa-between-conflict-mobile-telephony-and-im-mobility
#17
M De Bruijn, A Amadou, E Lewa Doksala, B Sangaré
The livelihoods of the Fulani mobile pastoralists in the Sahel, West and Central Africa are characterised by mobility (related to the needs of their animals), extensive social networks, and a focus on social ties as the basis of status and influence ('wealth in people'). The Sahel environment in which many Fulani nomads live has become embroiled in jihadism, conflict, and violence; at the same time, this region has experienced an increase in opportunities to connect through the wireless mobile communication system...
November 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/27881027/is-robotic-partial-nephrectomy-safe-for-t3a-renal-cell-carcinoma-experience-of-a-high-volume-center
#18
Hiury S Andrade, Homayoun Zargar, Oktay Akca, Onder Kara, Peter A Caputo, Daniel Ramirez, Guillermo Andrés, Robert J Stein, Shih-Chieh J Chueh, Jihad H Kaouk
PURPOSE: To compare the oncological and functional outcomes of robotic partial nephrectomy (RPN) with radical nephrectomy (RN) in renal-cell carcinoma (RCC) cases with pT3a staging. PATIENTS AND METHODS: A retrospective analysis of our IRB-approved nephrectomy database from 2005 to 2015 was performed. RPN and RN cases with confirmed RCC and pT3a staging were matched. Preoperative variables, functional, and oncological outcomes were compared between the groups, as well as Kaplan-Meier estimated overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS)...
January 5, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27864027/patterns-of-neural-activity-predict-picture-naming-performance-of-a-patient-with-chronic-aphasia
#19
Yune Sang Lee, Jihad T Zreik, Roy H Hamilton
Naming objects represents a substantial challenge for patients with chronic aphasia. This could be in part because the reorganized compensatory language networks of persons with aphasia may be less stable than the intact language systems of healthy individuals. Here, we hypothesized that the degree of stability would be instantiated by spatially differential neural patterns rather than either increased or diminished amplitudes of neural activity within a putative compensatory language system. We recruited a chronic aphasic patient (KL; 66 year-old male) who exhibited a semantic deficit (e...
January 8, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/27846791/clinical-experience-with-dolutegravir-abacavir-lamivudine-in-hiv-hcv-co-infected-patients-treated-with-a-sofosbuvir-based-regimen-safety-and-efficacy
#20
Tamara M Johnson, Raymund Sison, James P Fallon, Prerak P Shukla, Sristi Bhattarai, Herbert Galang, Richard Habeeb, Jihad Slim
BACKGROUND: There is no known reason to suspect an adverse drug interaction between dolutegravir-based antiretroviral therapy and sofosbuvir, simeprevir, or ledipasvir. There is a paucity of clinical data for this combination. METHODS: Prospective, open-label study of patients with HIV well controlled on dolutegravir, abacavir, and lamivudine, who were co-infected with HCV genotype 1, and required therapy with simeprevir plus sofosbuvir or sofosbuvir/ledipasvir single-tablet regimen (STR) for 12 weeks...
November 2016: HIV Clinical Trials
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