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Sander M Weckstein, Ethan J Weckstein, Christopher D Parker, Matthew W Westerman
BACKGROUND This case study was undertaken in an effort to assess whether children/adolescents with Autism Spectrum Disorder (ASD) experience improvement in comorbid ADHD following Cogmed Working Memory Training (CWMT). This treatment intervention has been shown to improve ADHD symptoms in children and adolescents; however, there have been no studies on its use with individuals with ASD. MATERIAL AND METHODS CWMT is a computer-based program that consists of 13 auditory, visual, visual spatial, and combined exercises that are practiced for 45 minutes a day, 5 days a week, for 5 weeks...
October 16, 2017: Medical Science Monitor Basic Research
Kyle F Shattuck, John W VanMeter
PURPOSE: To detect local cholinergic changes in human medial temporal lobe during configural working memory performance. MATERIALS AND METHODS: Proton magnetic resonance spectroscopy (1 H-MRS) measurements were acquired at 3T from a 2 × 2 × 3 cm voxel in right medial temporal lobe from 36 subjects during performance of a configural visual working memory task (cWMT). In order to compensate for expected task-based blood oxygenation level-dependent (BOLD) T2 * effects, resonance signal changes of unbound choline-containing metabolites (Cho) were referenced to an internal standard of creatine + phosphocreatine metabolites (Cre) and compared between four task blocks: rest, memorization, active memory maintenance, and recognition...
March 2018: Journal of Magnetic Resonance Imaging: JMRI
A Chacko, A-C V Bedard, D Marks, G Gopalan, N Feirsen, J Uderman, A Chimiklis, E Heber, M Cornwell, L Anderson, A Zwilling, M Ramon
The present study examines the potential of sequencing a neurocognitive intervention with behavioral parent training (BPT) to improve executive functions (EFs), psychiatric symptoms, and multiple indices of functional impairment in school-age children aged 7 to 11 years who have been diagnosed with attention-deficit/hyperactivity disorder (ADHD). Specifically, in a randomized controlled trial design, 85 children were assigned to either Cogmed Working Memory Training (CWMT) followed by an empirically supported, manualized BPT intervention, or to a placebo version of CWMT followed by the same BPT intervention...
May 2018: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
Zhong-Xu Liu, Victoria Lishak, Rosemary Tannock, Steven Woltering
Working memory and response control are conceptualized as functions that are part of a closely connected and integrated executive function system mediated by the prefrontal cortex and other related brain structures. In the present paper, we asked whether effects of intensive and adaptive computerized working memory training (CWMT) would generalize to enhancements in response control at behavioral and neural levels. A total of 135 postsecondary students with Attention-Deficit/Hyperactivity Disorder (ADHD), a condition associated with executive function impairments, were randomized into a Standard-length CWMT (45-min /session, 25 sessions), Shortened-length CWMT (15min/session, 25 sessions), and a waitlist group...
January 27, 2017: Neuropsychologia
Caitlin Hitchcock, Martin S Westwell
BACKGROUND: We explored whether school-based Cogmed Working Memory Training (CWMT) may optimise both academic and psychological outcomes at school. Training of executive control skills may form a novel approach to enhancing processes that predict academic achievement, such as task-related attention, and thereby academic performance, but also has the potential to improve the regulation of emotion, social problems and behavioural difficulties. METHODS: Primary school children (Mean age = 12 years, N = 148) were cluster-randomised to complete active CWMT, a nonadaptive/placebo version of CWMT, or no training...
February 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
Alan R Graham, William B Benninger
Many articles have been written about the effectiveness of Cogmed Working Memory Training (CWMT). As Cogmed licensees, we have provided CWMT to more than 350 trainees and have collected pre- and post-training assessment data and parental feedback from about 280 child and adolescent trainees and their parents. On all nine measures of working memory and other selected executive functions, we have found statistically significant improvement. We also offer many of the comments and feedback that we have received from families about the changes they have experienced...
July 2016: Applied Neuropsychology. Child
L Chang, G C Løhaugen, V Douet, E N Miller, J Skranes, T Ernst
BACKGROUND: Potent combined antiretroviral therapy decreased the incidence and severity of HIV-associated neurocognitive disorders (HAND); however, no specific effective pharmacotherapy exists for HAND. Patients with HIV commonly have deficits in working memory and attention, which may negatively impact many other cognitive domains, leading to HAND. Since HAND may lead to loss of independence in activities of daily living and negative emotional well-being, and incur a high economic burden, effective treatments for HAND are urgently needed...
February 2, 2016: Trials
Stina Söderqvist, Sissela Bergman Nutley
Training working memory (WM) using computerized programs has been shown to improve functions directly linked to WM such as following instructions and attention. These functions influence academic performance, which leads to the question of whether WM training can transfer to improved academic performance. We followed the academic performance of two age-matched groups during 2 years. As part of the curriculum in grade 4 (age 9-10), all students in one classroom (n = 20) completed Cogmed Working Memory Training (CWMT) whereas children in the other classroom (n = 22) received education as usual...
2015: Frontiers in Psychology
Marthe van der Donk, Anne-Claire Hiemstra-Beernink, Ariane Tjeenk-Kalff, Aryan van der Leij, Ramón Lindauer
The goal of this randomized controlled trial was to replicate and extend previous studies of Cogmed Working Memory Training (CWMT) in children with Attention-deficit/hyperactivity disorder (ADHD). While a large proportion of children with ADHD suffer from academic difficulties, only few previous efficacy studies have taken into account long term academic outcome measures. So far, results regarding academic outcome measures have been inconsistent. Hundred and two children with ADHD between the age of 8 and 12 years (both medicated and medication naïve) participated in current randomized controlled trial...
2015: Frontiers in Psychology
Christine M Steeger, Dawn M Gondoli, Bradley S Gibson, Rebecca A Morrissey
This study examined the individual and combined effects of two nonpharmacological treatments for attention deficit/hyperactivity disorder (ADHD): Cogmed working memory training (CWMT) for adolescents and behavioral parent training (BPT) for mothers. Ninety-one adolescents (ages 11-15) and their mothers were randomized to one of four CWMT and BPT treatment and active control (placebo) group combinations of 5-week interventions. At pre- and posttest, mothers and teachers completed rating forms, and adolescents completed neuropsychological measures of working memory (WM)...
2016: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
Helen Moor, Kristoffer Hylander, Jon Norberg
Wetlands provide multiple ecosystem services, the sustainable use of which requires knowledge of the underlying ecological mechanisms. Functional traits, particularly the community-weighted mean trait (CWMT), provide a strong link between species communities and ecosystem functioning. We here combine species distribution modeling and plant functional traits to estimate the direction of change of ecosystem processes under climate change. We model changes in CWMT values for traits relevant to three key services, focusing on the regional species pool in the Norrström area (central Sweden) and three main wetland types...
January 2015: Ambio
Karizma Mawjee, Steven Woltering, Nathan Lai, Howell Gotlieb, Reena Kronitz, Rosemary Tannock
OBJECTIVE: The aim of this study was to evaluate whether a shortened-length session of CogMed Working Memory Training (CWMT) would be a suitable active control group and evaluate study protocol to aid in design refinements for a larger randomized controlled trial (RCT). METHOD: Thirty-eight post-secondary students diagnosed with ADHD were randomized into 25 sessions of standard (45 min/session) or shortened (15 min/session) CWMT, or into a waitlist control group...
September 2017: Journal of Attention Disorders
Charles S Shinaver, Peter C Entwistle, Stina Söderqvist
Does Cogmed working-memory training (CWMT) work? Independent groups of reviewers have come to what appears to be starkly different conclusions to this question, causing somewhat of a debate within scientific and popular media. Here, various studies, meta-analyses, and reviews of the Cogmed research literature will be considered to provide an overview of our present understanding regarding the effects of CWMT. These will particularly be considered in light of two recent critical reviews published by Melby-Lervåg and Hulme ( 2013 ) and Shipstead, Hicks, and Engle ( 2012 ) and their arguments and conclusions assessed against current available evidence...
2014: Applied Neuropsychology. Child
Martine van Dongen-Boomsma, Madelon A Vollebregt, Jan K Buitelaar, Dorine Slaats-Willemse
BACKGROUND: Until now, working memory training has not reached sufficient evidence as effective treatment for ADHD core symptoms in children with ADHD; for young children with ADHD, no studies are available. To this end, a triple-blind, randomized, placebo-controlled study was designed to assess the efficacy of Cogmed Working Memory Training (CWMT) in young children with ADHD. METHODS: Fifty-one children (5-7 years) with a DSM-IV-TR diagnosis of ADHD (without current psychotropic medication) were randomly assigned to the active (adaptive) or placebo (nonadaptive) training condition for 25 sessions during 5 weeks...
August 2014: Journal of Child Psychology and Psychiatry, and Allied Disciplines
Susan E Gathercole
Chacko et al.'s investigation of the clinical utility of WM training to alleviate key symptoms of ADHD is timely and substantial, and marks a significant point in cognitive training research. Cogmed Working Memory Training (CWMT) involves intensive practice on multiple memory span tasks that increase in difficulty as performance improves with practice. Relative to a placebo version in which the span level of the memory tasks are kept at a low fixed level, Chacko et al. () found that CWMT boosted the performance of children with ADHD on short-term memory (STM) tasks similar to trained activities...
March 2014: Journal of Child Psychology and Psychiatry, and Allied Disciplines
A Chacko, A C Bedard, D J Marks, N Feirsen, J Z Uderman, A Chimiklis, E Rajwan, M Cornwell, L Anderson, A Zwilling, M Ramon
BACKGROUND: Cogmed Working Memory Training (CWMT) has received considerable attention as a promising intervention for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children. At the same time, methodological weaknesses in previous clinical trials call into question reported efficacy of CWMT. In particular, lack of equivalence in key aspects of CWMT (i.e., contingent reinforcement, time-on-task with computer training, parent-child interactions, supportive coaching) between CWMT and placebo versions of CWMT used in previous trials may account for the beneficial outcomes favoring CWMT...
March 2014: Journal of Child Psychology and Psychiatry, and Allied Disciplines
Anil Chacko, Nicole Feirsen, Anne-Claude Bedard, David Marks, Jodi Z Uderman, Alyssa Chimiklis
The current review applied the evidence-based treatment criteria espoused by the Society for Clinical Child and Adolescent Psychology (Silverman & Hinshaw, 2008 ) to specifically evaluate the short-term and longer term efficacy of Cogmed Working Memory Training (CWMT) as a treatment for youth with Attention-Deficit/Hyperactivity Disorder (ADHD). Utilizing a systematic literature search, 7 studies that employed the school-age version of CWMT were identified for this review. The data reviewed herein suggest mixed findings regarding the benefit of CWMT for youth with ADHD...
2013: Journal of Clinical Child and Adolescent Psychology
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