Susana Otero-Romero, Luciana Midaglia, Pere Carbonell-Mirabent, María Zuluaga, Ingrid Galán, Jordi Río, Georgina Arrambide, Marta Rodríguez-Barranco, Angela Vidal-Jordana, Joaquin Castillo, Breogán Rodríguez-Acevedo, Ana Zabalza, Carlos Nos, Manuel Comabella-Lopez, Patricia Mulero, Cristina Auger, Jaume Sastre-Garriga, Santiago Pérez-Hoyos, Alex Rovira, Xavier Montalban, Mar Tintoré
BACKGROUND AND PURPOSE: To evaluate the effect of menopause on disability accumulation in women followed from their clinically isolated syndrome (CIS). METHODS: We examined the longitudinal changes in Expanded Disability Status Scale (EDSS) scores from CIS until the last follow-up in women belonging to the Barcelona CIS prospective cohort, followed through their menopausal transition. The analysis is based on 13,718 EDSS measurements, with an average of 28 EDSS measurements per patient...
April 2022: European Journal of Neurology