Xiajing Chu, Jason Wang, Leonardo Ologundudu, Romina Brignardello-Petersen, Gordon H Guyatt, Paul Oykhman, Jonathan A Bernstein, Sarbjit S Saini, Lisa A Beck, Susan Waserman, Joseph Moellman, Dave A Khan, Moshe Ben-Shoshan, Diane R Baker, Eric T Oliver, Javed Sheikh, David Lang, Sameer K Mathur, Tonya Winders, Sanaz Eftekhari, Donna D Gardner, Lauren Runyon, Rachel N Asiniwasis, Emily F Cole, Jeffrey Chan, Kathryn E Wheeler, Kathryn P Trayes, Paul Tran, Derek K Chu
BACKGROUND: Short courses of adjunctive systemic corticosteroids are commonly used to treat acute urticaria and chronic urticaria flares (both with or without mast cell-mediated angioedema), but their benefits and harms are unclear. OBJECTIVE: To evaluate the efficacy and safety of treating acute urticaria or chronic urticaria flares with versus without systemic corticosteroids. METHODS: We searched MEDLINE, EMBASE, CENTRAL, CNKI, VIP, Wanfang, and CBM databases from inception to July 8, 2023 for randomized controlled trials of treating urticaria with versus without systemic corticosteroids...
April 18, 2024: Journal of Allergy and Clinical Immunology in Practice