keyword
MENU ▼
Read by QxMD icon Read
search

OT

keyword
https://www.readbyqxmd.com/read/28918226/chronic-central-oxytocin-infusion-impairs-sociability-in-mandarin-voles
#1
Peirong Du, Zhixiong He, Zhenlu Cai, Xin Hao, Na Dong, Wei Yuan, Wenjuan Hou, Jinfeng Yang, Rui Jia, Faodao Tai
Oxytocin (OT) has been reported to increase social contact, however some studies have related OT to reduced social contact, particularly with unfamiliar individuals. The underlying mechanisms of OT on social contact remain unclear. In this study, male mandarin vole (Microtus mandarinus), a socially monogamous rodent, was used as an animal model in which osmotic minipumps were used to intracerebroventricularly administer two continuous dosages of OT or saline for 12 consecutive days. We examined the effect of long-term OT treatment on social behavior, anxiety levels, and levels of oxytocin, vasopressin (AVP) and dopamine (DA) receptors, mRNA expression in the nucleus accumbens (NAcc), and medial amygdala (MeA)...
September 13, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28915249/effect-of-treatment-with-angiopoietin-2-and-vascular-endothelial-growth-factor-on-the-quality-of-xenografted-bovine-ovarian-tissue-in-mice
#2
Hyun Sun Kong, Jaewang Lee, Hye Won Youm, Seul Ki Kim, Jung Ryeol Lee, Chang Suk Suh, Seok Hyun Kim
Cryopreservation and transplantation of ovarian tissue (OT) represents a method for fertility preservation. However, as the transplantation is performed without vessel anastomosis, unavoidable ischemic damage occurs. To reduce this ischemic damage and improve outcomes after transplantation, we used two kind of angiogenic factors, angiopoietin-2 (ang-2) and vascular endothelial growth factor (VEGF). Fresh or vitrified-warmed bovine OTs were prepared for xenotransplantation (XT). Fresh OTs were immediately xenografted into nude mice (XT-Fresh)...
2017: PloS One
https://www.readbyqxmd.com/read/28904915/microbiological-surveillance-of-operation-theatres-five-year-retrospective-analysis-from-a-tertiary-care-hospital-in-north-india
#3
Dipender Kaur Najotra, Aneeta Singh Malhotra, Poonam Slathia, Shivani Raina, Ashok Dhar
INTRODUCTION: Microbiological contamination of air and environment in the operation theaters (OTs) are major risk factor for surgical site and other hospital-associated infections. OBJECTIVES: The aim was to identify bacterial colonization of surfaces and equipment and to determine the microbial contamination of air in the OTs of a tertiary care hospital. MATERIALS AND METHODS: Five years (January 2010-December 2014) retrospective analysis of the data obtained from routine microbiological surveillance of the five OTs of the hospital was done...
July 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28903036/culturing-ctls-under-hypoxic-conditions-enhances-their-cytolysis-and-improves-their-anti-tumor-function
#4
Yael Gropper, Tali Feferman, Tali Shalit, Tomer-Meir Salame, Ziv Porat, Guy Shakhar
Cytotoxic T lymphocytes (CTLs) used in immunotherapy are typically cultured under atmospheric O2 pressure but encounter hypoxic conditions inside tumors. Activating CTLs under hypoxic conditions has been shown to improve their cytotoxicity in vitro, but the mechanism employed and the implications for immunotherapy remain unknown. We activated and cultured OT-I CD8 T cells at either 1% or 20% O2. Hypoxic CTLs survived, as well as normoxic ones, in vitro but killed OVA-expressing B16 melanoma cells more efficiently...
September 12, 2017: Cell Reports
https://www.readbyqxmd.com/read/28901702/eating-attitudes-and-behaviours-of-students-enrolled-in-undergraduate-nutrition-and-dietetics-degrees
#5
Tetyana Rocks, Fiona Pelly, Gary Slater, Lisa A Martin
AIM: The prevalence of disordered eating has been frequently reported in university students; however, the prevalence amongst Australian undergraduate students studying degrees with a focus on nutrition is uncertain. The aims of this study were to: (i) assess eating attitudes and behaviours of students enrolled in nutrition and dietetics, (ii) compare those to students enrolled in another health degree of occupational therapy (OT) and (iii) explore possible relationships between eating attitudes and behaviours and other characteristics of both cohorts...
September 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28899880/effects-of-aging-and-resistance-training-in-rat-tendon-remodeling
#6
Rita C Marqueti, João L Q Durigan, Anderson José S Oliveira, Marcelo Shinyu Mekaro, Vinicius Guzzoni, Andrea A Aro, Edson Rosa Pimentel, Heloisa S Selistre-de-Araujo
In elderly persons, weak tendons contribute to functional limitations, injuries, and disability, but resistance training can attenuate this age-related decline. We evaluated the effects of resistance training on the extracellular matrix (ECM) of the calcaneal tendon (CT) in young and old rats and its effect on tendon remodeling. Wistar rats aged 3 mo (young, n = 30) and 20 mo (old, n = 30) were divided into 4 groups: young sedentary, young trained, old sedentary (OS), and old trained (OT). The training sessions were conducted over a 12-wk period...
September 12, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28899620/the-action-radius-of-oxytocin-release-in-the-mammalian-cns-from-single-vesicles-to-behavior
#7
REVIEW
Bice Chini, Matthijs Verhage, Valery Grinevich
The hypothalamic neuropeptide oxytocin (OT) has attracted the attention both of the scientific community and a general audience because of its prosocial effects in mammals, and OT is now seen as a facilitator of mammalian species propagation. Furthermore, OT is a candidate for the treatment of social deficits in several neuropsychiatric and neurodevelopmental conditions. Despite such possibilities and a long history of studies on OT behavioral effects, the mechanisms of OT actions in the brain remain poorly understood...
September 9, 2017: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/28895874/charge-transport-by-inverse-micelles-in-non-polar-media
#8
Filip Strubbe, Kristiaan Neyts
Charged inverse micelles play an important role in the electrical charging and the electrodynamics of nonpolar colloidal dispersion relevant for applications such as electronic ink displays and liquid toner printing. This review examines the properties and the behavior of charged inverse micelles in microscale devices in the absence of colloidal particles. It is discussed how charge in nonpolar liquids is stabilized in inverse micelles and how conductivity depends on the inverse micelle size, water content and ionic impurities...
September 12, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28894822/randomized-controlled-trial-demonstrating-cost-effective-method-of-olfactory-training-in-clinical-practice-essential-oils-at-uncontrolled-concentration
#9
Zara M Patel, Sarah K Wise, John M DelGaudio
OBJECTIVES: Published data examining the efficacy of olfactory training (OT) has used standardized concentrations of odorants and the Sniffin' Sticks testing method. Although well-validated, these methods are costly and time-intensive for the average otolaryngology practice. The purpose of our study was to evaluate the efficacy of using essential oils at random concentrations and the University of Pennsylvania Smell Test (UPSIT) for training and testing, and compare this with the existing data on OT...
April 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28892515/strong-interferon-gamma-mediated-cellular-immunity-to-scrub-typhus-demonstrated-using-a-novel-whole-cell-antigen-elispot-assay-in-rhesus-macaques-and-humans
#10
Manutsanun Sumonwiriya, Daniel H Paris, Piyanate Sunyakumthorn, Tippawan Anantatat, Kemajittra Jenjaroen, Suchintana Chumseng, Rawiwan Im-Erbsin, Ampai Tanganuchitcharnchai, Suthatip Jintaworn, Stuart D Blacksell, Fazle R Chowdhury, Barbara Kronsteiner-Dobramysl, Prapit Teparrukkul, Robin L Burke, Eric D Lombardini, Allen L Richards, Carl J Mason, James W Jones, Nicholas P J Day, Susanna J Dunachie
Scrub typhus is a febrile infection caused by the obligate intracellular bacterium Orientia tsutsugamushi, which causes significant morbidity and mortality across the Asia-Pacific region. The control of this vector-borne disease is challenging due to humans being dead-end hosts, vertical maintenance of the pathogen in the vector itself, and a potentially large rodent reservoir of unclear significance, coupled with a lack of accurate diagnostic tests. Development of an effective vaccine is highly desirable. This however requires better characterization of the natural immune response of this neglected but important disease...
September 11, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28891935/alteration-of-mammary-gland-development-and-gene-expression-by-in-utero-exposure-to-cadmium
#11
Daniela A Parodi, Morgan Greenfield, Claire Evans, Anna Chichura, Alexandra Alpaugh, James Williams, Kedra C Cyrus, Mary Beth Martin
Environmental exposure to estrogens and estrogen like contaminants during early development is thought to contribute to the risk of developing breast cancer primarily due to an early onset of puberty; however, exposure during key developing windows may also influence the risk of developing the disease. The goal of this study was to ask whether in utero exposure to the metalloestrogen cadmium alters mammary gland development due to acceleration of puberty onset or to an effect on early development of the mammary gland...
September 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28891043/treamed-locked-intramedullary-nailing-for-studying-femur-fracture-and-its-complications
#12
O Yoshino, J Brady, K Young, B Hardy, R Matthys, T Buxton, R Appleyard, J Tomka, D Dabirrahmani, P Woodford, M Fadia, R Steck, A Quail, R G Richards, Z J Balogh
Morbidity associated with femur fractures in polytrauma patients is known to be high. The many unsolved clinical questions include the immunological effect of the fracture and its fixation, timing of fracture fixation, management of fracture non-union, effect of infection and critical size of bone defects. The aim of this study was to establish a clinically-relevant and reproducible animal model with regards to histological, biomechanical and radiological changes during bone healing. A custom-designed intramedullary nail with interlocking system (RabbitNail, RISystem AG, Davos Platz, Switzerland) was used for fixation, following femur fracture...
September 11, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28890978/site-selective-tagging-of-proteins-by-pnictogen-mediated-self-assembly
#13
Christoph Nitsche, Mithun C Mahawaththa, Walter Becker, Thomas Huber, Gottfried Otting
Site-selective chemical protein modification is achieved by self-assembly of a specific di-cysteine motif, trivalent pnictogens (As, Sb or Bi) and an aromatic mercaptomethyl-based probe. The strategy is demonstrated with a quaternary complex involving Zika virus protease and a lanthanide ion, enabling paramagnetic nuclear magnetic resonance spectroscopy and luminescence measurements.
September 11, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28889808/maternal-immune-and-affiliative-biomarkers-and-sensitive-parenting-mediate-the-effects-of-chronic-early-trauma-on-child-anxiety
#14
A Ulmer-Yaniv, A Djalovski, K Yirmiya, G Halevi, O Zagoory-Sharon, R Feldman
BACKGROUND: Chronic early trauma alters children's stress reactivity and increases the prevalence of anxiety disorders; yet the neuroendocrine and immune mechanisms underpinning this effect are not fully clear. Animal studies indicate that the mother's physiology and behavior mediate offspring stress in a system-specific manner, but few studies tested this external-regulatory maternal role in human children exposed to chronic stress. METHODS: We followed a unique cohort of children exposed to continuous wartime trauma (N = 177; exposed; N = 101, controls; N = 76)...
September 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28889007/selective-deletion-of-the-oxytocin-gene-remodels-the-number-and-shape-of-dendritic-spines-in-the-medial-amygdala-of-males-with-and-without-sexual-experience
#15
Roberta Oriques Becker, Alberto A Rasia-Filho, Márcia Giovenardi
Oxytocin has central actions that modulate synaptic plasticity and the occurrence of social behavior in rodents. The posterodorsal medial amygdala (MePD) composes a sexually dimorphic neural circuit for the display of male sexual behavior. Local dendritic spines are notably plastic and affected by context-dependent social stimuli. Here, we examined the effects of the selective deletion of the OT gene (OTKO) in the number and shape of Golgi-impregnated dendritic spines in the MePD of näive and sexually experienced (SexExp) male mice (n=6 each group)...
September 6, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28887796/enabling-work-occupational-therapy-interventions-for-persons-with-occupational-injuries-and-diseases-a-scoping-review
#16
REVIEW
Alexa Jane T Blas, Kenneth Matthew B Beltran, Pauline Gail V Martinez, Daryl Patrick G Yao
Purpose This review aims to map the scope of published research on occupational therapy (OT) interventions and pertinent work and work-related outcomes for persons with occupational injuries and diseases. Methods The scoping review adapted Arksey and O'Malley's framework. Six electronic databases were searched. Ancestral search was also done on five systematic reviews. The search was conducted from September 2015 to October 2015. Interventions and outcomes were coded using the International Classification of Functioning, Disability and Health Core Set for Vocational Rehabilitation to plot trends...
September 8, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28882340/an-automated-and-self-cleaning-nano-liquid-chromatography-mass-spectrometry-platform-featuring-an-open-tubular-multi-hole-crystal-fiber-solid-phase-extraction-column-and-an-open-tubular-separation-column
#17
Meire Ribeiro da Silva, Ole Kristian Brandtzaeg, Tore Vehus, Fernando Mauro Lanças, Steven Ray Wilson, Elsa Lundanes
An open tubular (OT) sample preparation/separation platform was developed. A multi-channel polymer layer open tubular (mPLOT) solid phase extraction (SPE) column was prepared by wall-coating the 126 channels (8μm inner diameter (ID) each) of a crystal fiber capillary with an organic polymer, namely poly(styrene-co-octadecene-co-divinylbenzene) (PS-OD-DVB). The mPLOT SPE was coupled on-line with a 10μm×2m poly(styrene-co-divinylbenzene) (PS-DVB) OT liquid chromatography column with nanospray mass spectrometry (OTLC-MS)...
August 30, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28881460/endogenous-oxytocin-is-associated-with-the-experience-of-compassion-and-recalled-upbringing-in-borderline-personality-disorder
#18
Andreas Ebert, Marc-Andreas Edel, Paul Gilbert, Martin Brüne
BACKGROUND/OBJECTIVE: The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of compassion and recalled parental behavior during childhood. METHODS: Fifty-seven BPD patients and 43 healthy controls participated in the study. OT plasma levels were analyzed by radioimmunoassay...
September 7, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28879902/review-of-tremor-in-parkinson-s-disease-and-atypical-parkinsonian-disorders
#19
Pooja Mailankody, M Netravathi, Pramod Kumar Pal
Rest tremor (RT), a cardinal feature of Parkinson's disease (PD) is often accompanied by other types of tremor such as action tremor, which includes postural tremor, kinetic tremor, re-emergent tremor (ReT), and orthostatic tremor (OT). Literature on other tremors of PD, especially ReT and OT, is scarce. Tremor can be present in any of the atypical parkinsonian disorders such as progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, and dementia with Lewy bodies. RT can even be the presenting symptom of these disorders...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28878400/thiamine-antagonists-trigger-p53-dependent-apoptosis-in-differentiated-sh-sy5y-cells
#20
Sergiy Chornyy, Yulia Parkhomenko, Nataliya Chorna
Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions. However, there are limited data regarding the pursuant feedback between p53 transactivation and thiamine homeostasis. Impairment in thiamine metabolism can be induced experimentally via interference with the thiamine uptake and/or inhibition of the thiamin pyrophosphate-dependent enzymes using thiamine antagonists - amprolium (AM), oxythiamine (OT) or pyrithiamine (PT)...
September 6, 2017: Scientific Reports
keyword
keyword
65527
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"