keyword
MENU ▼
Read by QxMD icon Read
search

Phlebotomy

keyword
https://www.readbyqxmd.com/read/28715092/the-origins-of-oral-medicine-in-the-hippocratic-collected-works
#1
REVIEW
Helen Askitopoulou, Vasileia Nyktari, Alexandra Papaioannou, Georgios Stefanakis, Elina Konsolaki
The collected works of Hippocrates describe for the first time in a systematic way a large number of oral diseases, such as ulcers, inflammations, abscesses and tumours from the epiglottis, mouth, tongue, palate, uvula and the sublingual area. Several of these case reports are remarkable for the accurate observation of clinical symptoms and signs, the aetiology, the pathogenesis and their therapeutic approach in relation to prognosis. The Hippocratic authors report cases of 'aphthae' as part of a polysystemic disease, described many centuries later by Behçet and Adamantiades, while they associate features of splenomegaly from endemic malaria with gingivitis ('ulitis')...
July 17, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28711526/xpert-hiv-1-point-of-care-test-for-neonatal-diagnosis-of-hiv-in-the-birth-testing-programme-of-a-maternity-hospital-a-field-evaluation-study
#2
Karl-Günter Technau, Louise Kuhn, Ashraf Coovadia, Pamela M Murnane, Gayle Sherman
BACKGROUND: Point-of-care testing (POCT) among HIV-exposed infants might improve linkage to care relative to laboratory-based testing (LABT). We evaluated HIV-1 POCT at birth in the context of universal LABT in a maternity hospital and describe our implementation experience. METHODS: We did a field evaluation study between Oct 1, 2014, and April 30, 2016, at the urban Rahima Moosa Mother and Child Hospital (RMMCH), Johannesburg, South Africa. We aimed to sample consecutive neonates at birth with POCT (Cepheid Xpert HIV-1 Qualitative test) and compared results with those of LABT (Roche COBAS TaqMan HIV-1 Qualitative test) with respect to performance in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Cohen's κ coefficient, result return, antiretroviral treatment (ART) initiation, and coverage...
July 12, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28711126/care-of-metabolic-and-endocrine-conditions-in-the-observation-unit
#3
REVIEW
Anwar Dayan Osborne
Accelerated therapeutic protocols targeting metabolic conditions are ideal for observation unit care. Because many conditions, such as hypokalemia and hyperglycemia, have little to no diagnostic uncertainty, the care in the unit is often straightforward. Additionally, some components of care for the endocrine condition may exhaust services, such as phlebotomy. Hence, this discussion focuses resource utilization and management considerations for the purposes of matching the level of care to the severity of the conditions...
August 2017: Emergency Medicine Clinics of North America
https://www.readbyqxmd.com/read/28701427/controlling-phlebotomy-volume-diminishes-picu-transfusion-implementation-processes-and-impact
#4
Katherine Steffen, Allan Doctor, Julie Hoerr, Jeff Gill, Chris Markham, Sarah M Brown, Daniel Cohen, Rose Hansen, Emily Kryzer, Jessica Richards, Sara Small, Stacey Valentine, Jennifer L York, Enola K Proctor, Philip C Spinella
BACKGROUND AND OBJECTIVES: Phlebotomy excess contributes to anemia in PICU patients and increases the likelihood of red blood cell transfusion, which is associated with risk of adverse outcomes. Excessive phlebotomy reduction (EPR) strategies may reduce the need for transfusion, but have not been evaluated in a PICU population. We hypothesized that EPR strategies, facilitated by implementation science methods, would decrease excess blood drawn and reduce transfusion frequency. METHODS: Quantitative and qualitative methods were used...
July 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28699191/a-re-appraisal-of-the-benefit-risk-profile-of-hydroxyurea-in-polycythemia-vera-a-propensity-matched-study
#5
Tiziano Barbui, Alessandro M Vannucchi, Guido Finazzi, Maria Chiara Finazzi, Arianna Masciulli, Alessandra Carobbio, Arianna Ghirardi, Gianni Tognoni
The use of Hydroxyurea (HU) as first line therapy in polycythemia vera (PV) has been criticized because no solid demonstration that this drug prevents thrombosis or prolongs survival has been so far produced. Here we present the outcomes of a large cohort of patients with PV included in the European Collaborative Low-dose Aspirin (ECLAP) study. We selected 1,042 patients who, during the follow-up, had received only phlebotomy (PHL) or HU to maintain the hematocrit level<45%. To assure comparability, we conducted a propensity score matching analysis...
July 11, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28694735/what%C3%A2-s-floating-on-my-plasma
#6
Janne Cadamuro, Helmut Wiedemann, Thomas K Felder, Cornelia Mrazek, Ulrike Kipman, Oberkofler Hannes, Elisabeth Haschke-Becher
We report on a preanalytical issue we encountered during routine clinical chemistry analyses, potentially leading to deviated analysis results and believe that it might help other laboratories to overcome similar problems. In a heparin-gel tube we measured an implausible glucose value of 0.06 mmol/L. Re-measurement of the same sample resulted in a glucose value of 5.4 mmol/L. After excluding an analytical error, we inspected the sample closer and found a white material as well as fatty droplets floating on the surface of the plasma tube...
June 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28694729/the-alcohol-used-for-cleansing-the-venipuncture-site-does-not-jeopardize-blood-and-plasma-alcohol-measurement-with-head-space-gas-chromatography-and-an-enzymatic-assay
#7
Giuseppe Lippi, Ana-Maria Simundic, Giacomo Musile, Elisa Danese, Gianluca Salvagno, Franco Tagliaro
INTRODUCTION: This study aimed to establish whether an alcoholic antiseptic, wiped or not before venipuncture, may jeopardize alcohol testing with a commercial enzymatic assay and a reference head-space gas chromatography (GC) technique. MATERIALS AND METHODS: Venous blood was collected from 23 healthy volunteers, with two sequential procedures. In the first blood collection, 2 mL of alcoholic antiseptic (0.5% chlorhexidine, 70% ethanol) were place on a gauge pad, the venipuncture site of right arm was cleaned but the antiseptic was not let to dry before phlebotomy...
June 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28690893/blood-culture-contaminants-in-a-paediatric-population-retrospective-study-from-a-tertiary-hospital-in-oman
#8
Mohamed A El-Naggari, Sharef W Al-Mulaabed, Zakaria Al-Muharrmi, Renjith Mani, Rana Abdelrahim, Reem Abdwani
OBJECTIVES: Most children presenting with febrile illness require a blood culture to determine the causative organism as well as its sensitivity to antibiotics. However, false-positive results lead to unnecessary hospitalisations, prescriptions and tests. This study aimed to evaluate the impact of false-positive blood cultures among a paediatric population at a tertiary hospital in Oman. METHODS: This retrospective study included all 225 children <13 years old with positive blood cultures who presented to the Sultan Qaboos University Hospital, Muscat, Oman, between July 2011 and December 2013...
May 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28666715/-the-role-of-erythroferrone-in-iron-metabolism-from-experimental-results-to-pathogenesis
#9
N Vallet
In case of erythropoiesis, body iron needs to increase to enable the production of new red blood cells. In the 1950s, the observation of an increased digestive iron absorption in the case of phlebotomies had led to propose the existence of an "erythroid factor", which regulate the availability of iron for erythropoiesis in this situation. The factor regulating iron stores has been identified in 2000 to be hepcidin. Recently, in 2014, a new factor was discovered, which regulates iron metabolism, independently of iron stores and responds to the increased requirements for iron after stimulation of erythropoiesis by erythropoietin...
June 27, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28624580/proton-pump-inhibitors-decrease-phlebotomy-need-in-hfe-hemochromatosis-double-blind-randomized-placebo-controlled-trial
#10
Annick Vanclooster, Cees van Deursen, Reggy Jaspers, David Cassiman, Ger Koek
No abstract text is available yet for this article.
June 14, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28623659/immune-activation-of-platelets-in-response-to-serial-phlebotomy-in-pigtailed-macaques-macaca-nemestrina
#11
Kelly A Metcalf Pate, Meghan S Vermillion, Claire E Lyons, Kevin M Najarro, Robert J Adams
Serial phlebotomy is a common sampling practice for repeated-measures studies in biomedical research. In NHP, the effect ofserial blood collection on RBC parameters has been characterized, but the effects on platelet parameters and other aspects of thehemogram have not been well studied. We sought to characterize the circulating platelet phenotype throughout the course of 7serial phlebotomies spanning 30 d in pigtailed macaques (Macaca nemestrina). Phlebotomy was performed on 23 animals at days0, 2, 4, 7, 10, 21, and 30 to quantify the circulating platelet count and markers of both hemostatic and immune platelet activation...
June 16, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28606591/safety-and-immunogenicity-of-the-rvsv%C3%A2-g-zebov-gp-ebola-virus-vaccine-candidate-in-healthy-adults-a-phase-1b-randomised-multicentre-double-blind-placebo-controlled-dose-response-study
#12
D Gray Heppner, Tracy L Kemp, Brian K Martin, William J Ramsey, Richard Nichols, Emily J Dasen, Charles J Link, Rituparna Das, Zhi Jin Xu, Eric A Sheldon, Teresa A Nowak, Thomas P Monath
BACKGROUND: The 2014 Zaire Ebola virus outbreak highlighted the need for a safe, effective vaccine with a rapid onset of protection. We report the safety and immunogenicity of the recombinant vesicular stomatitis virus-Zaire Ebola virus envelope glycoprotein vaccine (rVSV∆G-ZEBOV-GP) across a 6 log10 dose range in two sequential cohorts. METHODS: In this phase 1b double-blind, placebo-controlled, dose-response study we enrolled and randomly assigned healthy adults (aged 18-61 years) at eight study sites in the USA to receive a single injection of vaccine or placebo, administered by intramuscular injection...
June 9, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28601479/effect-of-the-use-of-buzzy-during-phlebotomy-on-pain-and-individual-satisfaction-in-blood-donors
#13
Dilek Yılmaz, Yasemin Heper, Leyla Gözler
Phlebotomy causes pain and discomfort to adults. The objective of this study was to investigate the effect of the use of Buzzy on phlebotomy satisfaction and pain relating to the phlebotomy process in healthy adult blood donors voluntarily donating blood. This was a prospective, randomized, controlled experimental study. The research sample was made up of 90 healthy adult men. These individuals were randomly assigned to an experimental group (Buzzy group), a placebo control group, and a nonintervention control group...
June 7, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/28593910/the-eflm-strategy-for-harmonization-of-the-preanalytical-phase
#14
REVIEW
Giuseppe Lippi, Ana-Maria Simundic
The Working Group for the Preanalytical Phase (WG-PRE) was officially established by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) in 2013, with the aim of improving harmonization in the preanalytical phase across European member societies. Since its early birth, the WG-PRE has already completed a number of projects, including harmonizing the definition of fasting status, patient and blood tubes identification, color coding of blood collection tubes, sequence of tubes during blood drawing and participation in the development of suitable preanalytical quality indicators...
June 3, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28593739/systematic-review-and-meta-analysis-to-determine-the-impact-of-iron-depletion-in-dysmetabolic-iron-overload-syndrome-and-nonalcoholic-fatty-liver-disease
#15
Arvind R Murali, Ashutosh Gupta, Kyle Brown
AIMS: Iron reduction has been proposed as treatment for dysmetabolic iron overload syndrome (DIOS) and nonalcoholic fatty liver disease (NAFLD), but results of published trials are conflicting. We aimed to perform a systematic review and meta-analysis to determine the impact of phlebotomy in DIOS and NAFLD. METHODS: We searched multiple databases systematically for studies evaluating impact of phlebotomy in DIOS and NAFLD. We calculated weighted summary estimates using inverse variance method...
June 7, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28577649/patient-posture-for-blood-collection-by-venipuncture-recall-for-standardization-after-28-years
#16
Gabriel Lima-Oliveira, Gian Cesare Guidi, Gian Luca Salvagno, Elisa Danese, Martina Montagnana, Giuseppe Lippi
BACKGROUND: Although data about the effect of posture on routine hematological testing were published 28 years ago, this pre-analytical issue has not been standardized so far. This study was planned to evaluate whether postural changes influence the results of hematology testing. METHODS: A complete blood count was performed in 19 healthy volunteers after 25min in the supine position, 20min in a sitting position and 20min stationary standing in an upright position...
April 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/28542080/manuscript-title-multidisciplinary-point-of-care-testing-in-south-african-primary-healthcare-clinics-accelerates-hiv-art-initiation-but-does-not-alter-retention-in-care
#17
Wendy S Stevens, Natasha M Gous, William B MacLeod, Lawrence C Long, Ebrahim Variava, Neil A Martinson, Ian Sanne, Regina Osih, Lesley E Scott
BACKGROUND: Lack of accessible laboratory infrastructure limits HIV antiretroviral (ART) treatment initiation, monitoring and retention in many resource-limited settings. Point-of-care testing (POCT) is advocated as a mechanism to overcome these limitations. We executed a pragmatic, prospective, randomized, controlled trial comparing the impact of POCT versus standard-of-care (SOC) on treatment initiation and retention in care. METHOD: Selected POC technologies were embedded at 3 primary health clinics in South Africa...
May 23, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28535866/comparing-phlebotomy-by-tail-tip-amputation-facial-vein-puncture-and-tail-vein-incision-in-c57bl-6-mice-by-using-physiologic-and-behavioral-metrics-of-pain-and-distress
#18
Elizabeth S Moore, Thomas A Cleland, Wendy O Williams, Christine M Peterson, Bhupinder Singh, Teresa L Southard, Bret Pasch, Rachael N Labitt, Erin K Daugherity
Tail tip amputation with minimal restraint is not widely used for mouse phlebotomy. In part, this infrequency may reflect policies influenced by tail tip amputation procedures for genotyping, which involve greater handling and tissue removal. To assess tail tip amputation with minimal restraint as a phlebotomy technique, we compared it with 2 more common methods: scruffing with facial vein puncture and lateral tail vein incision with minimal restraint. Blood glucose levels, audible and ultrasonic vocalizations, postphlebotomy activity and grooming behavior, open field and elevated plus maze behaviors, nest-building scores, and histologic changes at the phlebotomy site were evaluated...
May 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28508379/-retinal-pigment-epithelial-detachment-in-hyperviscosity-syndrome
#19
V C Müller, N Mihailovic, C R Clemens, F Alten, N Eter
We present a case of a 57-year-old woman who reported bilateral visual impairment since 2 weeks. She had a medical history of congenital, cyanotic heart failure. Funduscopic examination revealed serous retinal detachment on the left side, central subneurosensory detachment on the right side, retinal vessel tortuosity and multiple retinal haemorrhages in the periphery. As blood analysis showed a distinct increase in haemoglobin and haematocrit, hyperviscosity syndrome was suspected to have caused bilateral serous retinal detachment...
May 15, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28500860/interventions-for-preventing-silent-cerebral-infarcts-in-people-with-sickle-cell-disease
#20
REVIEW
Lise J Estcourt, Patricia M Fortin, Sally Hopewell, Marialena Trivella, Carolyn Doree, Miguel R Abboud
BACKGROUND: Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta globin) genes. SCD can cause severe pain, significant end-organ damage, pulmonary complications, and premature death. Silent cerebral infarcts are the commonest neurological complication in children and probably adults with SCD. Silent cerebral infarcts also affect academic performance, increase cognitive deficits and may lower intelligence quotient...
May 13, 2017: Cochrane Database of Systematic Reviews
keyword
keyword
6552
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"