keyword
https://read.qxmd.com/read/38639020/stripping-versus-ligation-of-vas-deferens-in-microscopic-denervation-of-spermatic-cord-in-men-with-chronic-orchialgia-a-multicenter-study
#1
JOURNAL ARTICLE
Adnan El-Achkar, Muhammed Hammad, David Barham, Chad A Service, Darshan Patel, Tung Chin Hsieh, Jesse Mills, Reza Kianian, Sriram Eleswarapu, Matthew Ziegelmann, Ryan Smith, Darren Bryk, Helen L Bernie, Melissa Egert, Omer Raheem, Kiarad Fendereski, Kelli Gross, Alex Pastuszak, James Hotaling, Faysal Yafi
BACKGROUND: Microdenervation of the spermatic cord (MSCD) is an effective treatment modality for men with intractable scrotal content pain. For patients not interested in preserving fertility, some centers advocate ligation of the vas during denervation, while others prefer stripping of the vas deferens to preserve the vasal artery, hence preserving vasculature to the testis and possibly decreasing post-operative congestion pain. OBJECTIVE: To compare outcomes of patients with chronic orchialgia, who underwent MSCD by either stripping or ligating the vas deferens...
April 19, 2024: Andrology
https://read.qxmd.com/read/38511211/postnatal-survival-of-phrenic-motor-neurons-is-promoted-by-bdnf-trkb-fl-signaling
#2
JOURNAL ARTICLE
Joline E Brandenburg, Matthew J Fogarty, Wen-Zhi Zhan, Leo A Kopper, Gary C Sieck
The number of motor neurons (MNs) declines precipitously during the final trimester before birth. Thereafter, the number of MNs remains relatively stable, with their connections to skeletal muscle dependent on neurotrophins, including brain-derived neurotrophic factor (BDNF) signaling through its high affinity full length tropomyosin related kinase receptor subtype B (TrkB.FL) receptor. As a genetic knockout of BDNF leads to extensive MN loss and postnatal death within 1-2 days after birth; we tested the hypothesis that postnatal inhibition of BDNF/TrkB...
March 21, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38330026/impact-of-two-endotracheal-tube-fixation-on-the-incidence-of-peri-oral-lesions-elastic-adhesive-strips-versus-cord-in-a-protective-sheath-study-protocol-for-a-cluster-cross-over-randomized-trial
#3
JOURNAL ARTICLE
Vanessa Zinzoni, Lucie Planche, Sophie Le Potier, Laurence Robin, Cécile Le Parco, Philippe Terrat, Marie-Hélène Leroyer, Romain Atger, Jérôme E Dauvergne, Lucie Muller, Laetitia Fontaine, Célina Morand, Pascaline Dennemont, Ophélie Paillard, Servane Vastral, Baptiste Dardaine, Sylvie Le Guillou, Natacha Maquigneau, Stéphanie Martin, Jean-Claude Lachérade
BACKGROUND: Endotracheal tube fixation in ventilated patients must be appropriate to ensure security during mechanical ventilation and prevent skin lesions. The incidence of endotracheal tube-caused pressure ulcers ranges from 7% to 45%. Various endotracheal tube fixations are used in intensive care units (ICUs) worldwide. By pressure exercised on the skin, these systems could lead to mucosal and skin peri-oral lesions. The main objective of this study is to evaluate the impact of the two fixation systems most commonly used in French ICUs (adhesive elastic band versus fixation cord with PolyVinyl Chloride (PVC) sheath) on the incidence of these peri-oral skin lesions...
2024: PloS One
https://read.qxmd.com/read/38160353/dysfunctional-bladder-morphology-and-functional-impairments-are-identified-in-the-alzheimer-s-disease-appnl-g-f-nl-g-f-murine-model
#4
JOURNAL ARTICLE
Yingying Ge, Alya S AlObaidi, George A Kuchel, Jenna M Bartley, Phillip P Smith, Wanxia He, Xiangyou Hu
BACKGROUND: While symptoms related to lower urinary tract dysfunction (LUTD) are common in individuals with Alzheimer's disease (AD), pathophysiological links between AD and LUTD remain unclear. OBJECTIVE: This study aimed to investigate whether AD neuropathology would cause autonomic dysfunction along the spinal cord-bladder axis, which could result in alterations in bladder muscle kinetics. METHODS: We utilized APPNL-G-F/NL-G-F knock-in (APP KI) and APPwt/wt (wild-type) mice at two different ages, 4- and 10-month-old, to investigate how AD impacts bladder tissue function by immunohistochemistry, western blotting, and pharmacomyography...
December 23, 2023: Journal of Alzheimer's Disease: JAD
https://read.qxmd.com/read/37879946/electroacupuncture-inhibits-pdk1-akt-hcn4-pathway-to-improve-neurogenic-urinary-retention-in-rats
#5
JOURNAL ARTICLE
Zheng-Fei Li, Ren Zhang, Guo-Rui Zhao, Yao Kuang
OBJECTIVES: To observe the therapeutic effect of electroacupuncture (EA) on neurogenic urinary retention rats, so as to explore the underlying mechanism of EA in treating neurogenic urinary retention by focusing on 3-phosphoinositide-dependent protein kinase 1 (PDK1)/protein kinase B (Akt)/hyperpolarization activated cyclic nucleotide-gated cation channel 4 (HCN4) pathway. METHODS: Female SD rats were randomly divided into sham operation, model, EA, PDK1 inhibitor, HCN4 blocker and EA + HCN4 blocker groups, with 20 rats in each group...
October 25, 2023: Zhen Ci Yan Jiu, Acupuncture Research
https://read.qxmd.com/read/37788973/comparative-outcome-data-using-different-techniques-for-posterior-lumbar-fusion-a-large-single-center-study
#6
JOURNAL ARTICLE
Daniel Lewis, Shivan Marya, Roberto Carrasco, Silviu Sabou, John Leach
STUDY DESIGN: Retrospective single-center study. PURPOSE: This study aims to evaluate perioperative and intermediate-term clinical outcomes of patients undergoing different lumbar fusion techniques. OVERVIEW OF LITERATURE: Various open and minimally invasive techniques for lumbar fusion are available, but previous studies comparing lumbar fusion techniques have heterogeneous data, making interpretation challenging. METHODS: Between 2011 and 2018, data from 447 consecutive patients undergoing one/two-level lumbar fusion were analyzed...
October 2023: Asian Spine Journal
https://read.qxmd.com/read/37641292/effect-of-milk-flow-rate-switch-point-settings-on-milking-duration-and-udder-health-throughout-lactation
#7
JOURNAL ARTICLE
J Upton, M Browne, P Silva Bolona
The objective of this study was to quantify the effects of different milk flow-rate switch-point settings on milking duration, SCC, strip milk, teat condition and milk yield in a grass based system in a long-term experiment. Much work has already been conducted providing strong support for significant reduction in milking duration without impact on yield through increasing the flow-rate switch-point at which vacuum to the milking cluster ceases and the cluster is removed from the cow by means of a retracting cord...
August 23, 2023: Journal of Dairy Science
https://read.qxmd.com/read/37396586/case-report-cardiac-metastatic-uterine-intravenous-leiomyomatosis-excision-with-extracorporeal-venous-shunt-under-the-guidance-of-3-dimensional-printing
#8
Hong Chen, Yu Mao, Hongtao Xie, Dejun Liu, Shun Zhang, Yongcang Tian, Jian Yang, Benjian Bai
Intravenous leiomyomatosis (IVL) is relatively rare, and the incidence of cardiac IVL is even lower. The case report introduces a 48-year-old woman with two episodes of syncope in 2021. Echocardiography showed a cord-like mass in the inferior vena cava (IVC), right atrium (RA), right ventricle (RV) and pulmonary artery. Computed tomography venography and magnetic resonance imaging showed strips in RA, RV, IVC, right common iliac vein, and internal iliac vein, as well as a round-like mass in the right uterine adnexa...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/37390048/the-invisible-plant-technology-of-prehistoric-southeast-asia-indirect-evidence-for-basket-and-rope-making-at-tabon-cave-philippines-39-33-000-years-ago
#9
JOURNAL ARTICLE
Hermine Xhauflair, Sheldon Jago-On, Timothy James Vitales, Dante Manipon, Noel Amano, John Rey Callado, Danilo Tandang, Céline Kerfant, Omar Choa, Alfred Pawlik
A large part of our material culture is made of organic materials, and this was likely the case also during prehistory. Amongst this prehistoric organic material culture are textiles and cordages, taking advantage of the flexibility and resistance of plant fibres. While in very exceptional cases and under very favourable circumstances, fragments of baskets and cords have survived and were discovered in late Pleistocene and Holocene archaeological sites, these objects are generally not preserved, especially in tropical regions...
2023: PloS One
https://read.qxmd.com/read/37350972/clinical-characteristics-and-prognostic-factors-for-short-term-outcomes-of-autoimmune-glial-fibrillary-acidic-protein-astrocytopathy-a-retrospective-analysis-of-33-patients
#10
JOURNAL ARTICLE
Wanwan Zhang, Yinyin Xie, Yali Wang, Fengxia Liu, Li Wang, Yajun Lian, Hongbo Liu, Cui Wang, Nanchang Xie
BACKGROUND: Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a recently discovered inflammatory central nervous system (CNS) disease, whose clinical characteristics and prognostic factors for short-term outcomes have not been defined yet. We aimed to assess the symptoms, laboratory tests, imaging findings, treatment, and short-term prognosis of GFAP-A. METHODS: A double-center retrospective cohort study was performed between May 2018 and July 2022...
2023: Frontiers in Immunology
https://read.qxmd.com/read/37308055/construction-and-optimization-of-a-coculture-system-of-mouse-brain-microvascular-endothelial-cells-and-myelin-debris
#11
JOURNAL ARTICLE
Chengjie Wu, Lei Shi, Yong Ma, Yalan Pan, Lining Wang, Sixian Chen, Yafeng Zhang, Jianwei Wang, Mengmin Liu, Yang Guo
Microvascular endothelial cells are a newly discovered cell type involved in the phagocytosis of myelin debris, which play a key role in the repair of spinal cord injuries. Several methods for the preparation of myelin debris and parameters for constructing a coculture system of microvascular endothelial cells and myelin debris are available, but no systematic studies have yet been conducted, which hinders further exploration of the mechanisms of demyelinating disease repair. Herein, we aimed to develop a standardized method for this process...
June 10, 2023: Neuroscience Letters
https://read.qxmd.com/read/37244364/release-of-6-nitrodopamine-from-human-popliteal-artery-and-vein
#12
JOURNAL ARTICLE
Luis Frederico Gerbase de Oliveira, José Britto-Júnior, Antonio Tiago Lima, Manoel Odorico Moraes, Maria Elisabete A Moraes, Valéria Barbosa de Souza, André Almeida Schenka, Fabiola Z Monica, Gilberto De Nucci
6-Nitrodopamine (6-ND) is a novel catecholamine that is released from human umbilical cord vessels, and it causes vascular relaxation by acting as a dopamine D2 -receptor antagonist. Here it was investigated whether human peripheral vessels obtained from patients who have undergone surgery for leg amputation release 6-ND, and its action in these tissues. Popliteal artery and vein strips present basal release of 6-ND, as measure by liquid chromatography coupled to tandem mass spectrometry. The release was significantly reduced when the tissues were pre-treated with the nitric oxide synthase inhibitor L-NAME (100 μM), or when the endothelium was mechanically removed...
May 25, 2023: Life Sciences
https://read.qxmd.com/read/37138291/the-effects-of-aerobic-exercise-on-neuroimmune-responses-in-animals-with-traumatic-peripheral-nerve-injury-a-systematic-review-with-meta-analyses
#13
REVIEW
Marije L S Sleijser-Koehorst, Meghan A Koop, Michel W Coppieters, Ivo J Lutke Schipholt, Nemanja Radisic, Carlijn R Hooijmans, Gwendolyne G M Scholten-Peeters
BACKGROUND: Increasing pre-clinical evidence suggests that aerobic exercise positively modulates neuroimmune responses following traumatic nerve injury. However, meta-analyses on neuroimmune outcomes are currently still lacking. This study aimed to synthesize the pre-clinical literature on the effects of aerobic exercise on neuroimmune responses following peripheral nerve injury. METHODS: MEDLINE (via Pubmed), EMBASE and Web of Science were searched. Controlled experimental studies on the effect of aerobic exercise on neuroimmune responses in animals with a traumatically induced peripheral neuropathy were considered...
May 3, 2023: Journal of Neuroinflammation
https://read.qxmd.com/read/37128139/ectopic-adrenal-cortical-tissue-presenting-as-gastrohepatic-ligament-lymph-node-diagnosed-by-fine-needle-aspiration-a-case-report
#14
JOURNAL ARTICLE
Linh Ho, Maria Luisa C Policarpio-Nicolas
Ectopic adrenal cortical tissue has been reported in several locations, most often involving the retroperitoneal fat close to the adrenal gland. The reported cases presenting adjacent or proximal to the stomach are rare and mostly diagnosed on histology. To our knowledge, the cytologic features of ectopic adrenal cortical tissue diagnosed on fine needle aspiration are not well documented in the cytology literature. We describe the cytologic features of ectopic adrenal cortex which initially presented on imaging study as an enlarged gastrohepatic ligament "lymph node" on a patient with gastric signet ring cell carcinoma...
June 2023: Diagnostic Cytopathology
https://read.qxmd.com/read/37080154/adult-upper-limb-forearm-lymphoma-hygroma-cystic-lymphangioma-a-case-report
#15
Yingkang Zhu, Sufen Li, Lei Zhou, Zunpeng Liu
INTRODUCTION: Lymphoma hygroma (LH) that is the most common type of lymphangioma, but it rarely occurs in the forearm. It may show localized invasive behavior, but is benign. CASE PRESENTATION: A 42-year-old woman presented to our hospital with a growing strip-like mass in the right forearm that had been detected 3 years earlier. Ultrasound examination showed a subcutaneous strip of low back vocal cords on the right forearm. Further magnetic resonance imaging (MRI) showed irregular strip-like dilated lymphatic vessels characteristic of LH with low T1 signal intensity and high T2 signal intensity...
April 14, 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/36587384/the-role-of-bioinformatics-and-imaging-models-in-tumorigenesis-and-treatment-response-of-brain-and-spinal-cord-neoplasm
#16
JOURNAL ARTICLE
Pooja Verma, Ravi Shanker, Vinal Patel, Mahua Bhattacharya
This chapter focuses on the division and location of brain deformities such as tumors in magnetic resonance imaging (MRI) through Chan-Vese active contour segmentation. Brain tumor division and identification is a major test in the area of biomedical picture processing. To detect the size and location of the tumor, various techniques are available, but active contour gives accurate knowledge of the region for segmentation. Chan-Vese Active contour method provides independent, robust and more flexible segmentation...
2023: Advances in Experimental Medicine and Biology
https://read.qxmd.com/read/36314060/bioelectrochemical-extraction-of-ammonium-from-low-strength-wastewater-with-concomitant-generation-of-high-purity-hydrogen
#17
JOURNAL ARTICLE
Ka Yu Cheng, Anna H Kaksonen, Ralf Cord-Ruwisch
Bioelectrochemical systems (BES) are emerging environmental biotechnology for recovering ammonia from waste streams. It has been tested extensively for treating ammonium-rich wastewater. This study examined the suitability of BES to facilitate carbon removal and ammonium extraction from a low ammonium liquor (3.7 mM) that mimics municipal wastewater, and concomitant production of high-purity hydrogen gas, which could potentially be harnessed as a fuel or internally recycled for ammonia stripping. Results showed that a two-chamber cation exchange membrane-equipped BES enabled a high hydrogen yield (22...
October 31, 2022: Environmental Technology
https://read.qxmd.com/read/36129535/the-effect-of-placental-transfusion-on-hemodynamics-in-premature-newborns-a-randomized-controlled-trial
#18
JOURNAL ARTICLE
Marwa Mohamed Farag, Mohamed Alaa Eldin Hassan Thabet, Ali Mohamed Abd-Almohsen, Heba Idris Abudeif Mohammed Ibrahim
Despite of growing evidence of the beneficial effects of placental transfusion techniques, there is no available sufficient data about their effects on vulnerable hemodynamics and myocardium of premature infants. The purpose of this work is to study ventricular functions and hemodynamics after applying different placental transfusion techniques, delayed cord clamping (DCC), cut cord milking (C-UCM), and intact cord milking (I-UCM). Sixty-four infants delivered whether by C-section or vaginal delivery were randomly assigned to undergo C-UCM (20-30 cm), I-UCM (3-4 strippings), and DCC (30-60 s)...
September 21, 2022: European Journal of Pediatrics
https://read.qxmd.com/read/35892134/participatory-methods-to-develop-health-education-for-pw-sci-perspectives-on-occupational-justice
#19
JOURNAL ARTICLE
Moussa K Abu Mostafa, Nicola A Plastow, Maggi Savin-Baden
BACKGROUND.: Many people with spinal cord injury (PW-SCI) in the Gaza Strip in Palestine are discharged from inpatient rehabilitation with limitations in their ability to meet basic needs, and reach their full potential. There is limited evidence of how clinicians can promote occupational justice for PW-SCI. PURPOSE.: To describe participants' perspectives revealed during a participatory action research (PAR) process used to develop an education manual for PW-SCI in Gaza, using Participatory Occupational Justice as a lens...
July 26, 2022: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://read.qxmd.com/read/35867399/the-impact-of-an-evidence-informed-spinal-cord-injury-activities-of-daily-living-education-manual-sadl-em-protocol-for-a-randomized-controlled-trial
#20
JOURNAL ARTICLE
Moussa Abu Mostafa, Nicola Ann Plastow, Maggi Savin-Baden, Birhanu Ayele
BACKGROUND: Spinal cord injury (SCI) is a catastrophic injury associated with functional loss and life-threatening complications. Many people with SCI in the Gaza Strip of Palestine are discharged from inpatient rehabilitation to the community while still lacking many daily life skills. This randomized controlled trial (RCT) seeks to test the impact of the Spinal Cord Injury Activities of Daily Living Education Manual (SADL-eM)-an evidence-based occupational therapy patient educational intervention-on rehabilitation outcomes...
July 22, 2022: JMIR Research Protocols
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