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cord milking

Lucille Arragain, Myrielle Dupont-Rouzeyrol, Olivia O'Connor, Nathalie Sigur, Jean-Paul Grangeon, Emilie Huguon, Clothilde Dechanet, Cécile Cazorla, Ann-Claire Gourinat, Elodie Descloux
: We investigated 10 mother-newborn pairs and found a 90% rate of dengue virus (DENV) transmission during the perinatal period. Here, we describe DENV kinetics in the sera of newborns before the onset of disease. Of the breast-milk samples analyzed, 75% tested positive for DENV. BACKGROUND: Dengue is the most common mosquito-borne viral disease in humans. With this study, we aimed to investigate the risk of vertical (DENV) transmission during the peripartum period and to describe its viral kinetics in serum and breast milk...
October 19, 2016: Journal of the Pediatric Infectious Diseases Society
G Sorin, B Tosello
Anemia of prematurity remains a common complication despite recent advances in perinatal and neonatal medicine. The delayed cord clamping (at least 30seconds as recommended) has several benefits: increased hemoglobin and hematocrit levels at birth, improved initial hemodynamic, decreased incidence of transfusions and intraventricular hemorrhages. When the birth transition is difficult, wait 30seconds before clamping can be impossible. So as not to interfere with the neonatal resuscitation, the "milking" has been proposed as an alternative method to the delayed cord clamping...
September 13, 2016: Gynécologie, Obstétrique & Fertilité
Shivam Agarwal, Vijay Jaiswal, Dharamveer Singh, Prateek Jaiswal, Amit Garg, Amit Upadhyay
AIM: Placental redistribution has been shown to improve haematological outcomes in the immediate neonatal period and early infancy. This study compared the effects of delayed cord clamping (DCC) and umbilical cord milking (UCM) on haematological and growth parameters at 12 months of age. METHODS: This was a follow-up study of a randomised control trial, conducted in a tertiary care paediatric centre from August 2013 to August 2014. We studied 200 apparently healthy Indian infants randomised at birth to receive DCC for 60-90 seconds or UCM...
November 2016: Acta Paediatrica
Sean M Bugel, Josephine A Bonventre, Robert L Tanguay
Flavonoids are a large, structurally diverse class of bioactive naturally occurring chemicals commonly detected in breast milk, soy based infant formulas, amniotic fluid, and fetal cord blood. The potential for pervasive early life stage exposures raises concerns for perturbation of embryogenesis, though developmental toxicity and bioactivity information is limited for many flavonoids. Therefore, we evaluated a suite of 24 flavonoid and flavonoid-like chemicals using a zebrafish embryo-larval toxicity bioassay - an alternative model for investigating developmental toxicity of environmentally relevant chemicals...
August 4, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
Sana Ullah, Khaista Rahman, Mehdi Hedayati
BACKGROUND: Hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. It is a multifactorial disorder with many symptoms. Generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. This review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical approaches towards hyperbilirubinemia, different precautionary measures for the parents of babies suffering from hyperbilirubinemia and different remedial therapeutic measures for its treatment...
May 2016: Iranian Journal of Public Health
Nina Iszatt, Hein Stigum, Eva Govarts, Lubica Palkovicova Murinova, Greet Schoeters, Tomas Trnovec, Juliette Legler, Cathrine Thomsen, Gudrun Koppen, Merete Eggesbø
BACKGROUND: Dioxins and dioxin-like compounds are endocrine disrupting chemicals (EDCs). Experimental studies suggest perinatal exposure to EDCs results in later obesity. However, the few epidemiological investigations on dioxins are inconclusive. We investigated perinatal exposure to dioxins and dioxin-like compounds, infant growth and body mass index (BMI) in childhood. METHODS: We pooled data from 3 European birth cohorts (Belgian, Norwegian, Slovak) with exposure assessment in cord blood or breast milk...
September 2016: Environment International
Christine Barthow, Kristin Wickens, Thorsten Stanley, Edwin A Mitchell, Robyn Maude, Peter Abels, Gordon Purdie, Rinki Murphy, Peter Stone, Janice Kang, Fiona Hood, Judy Rowden, Phillipa Barnes, Penny Fitzharris, Jeffrey Craig, Rebecca F Slykerman, Julian Crane
BACKGROUND: Worldwide there is increasing interest in the manipulation of human gut microbiota by the use of probiotic supplements to modify or prevent a range of communicable and non-communicable diseases. Probiotic interventions administered during pregnancy and breastfeeding offer a unique opportunity to influence a range of important maternal and infant outcomes. The aim of the Probiotics in Pregnancy Study (PiP Study) is to assess if supplementation by the probiotic Lactobacillus rhamnosus HN001 administered to women from early pregnancy and while breastfeeding can reduce the rates of infant eczema and atopic sensitisation at 1 year, and maternal gestational diabetes mellitus, bacterial vaginosis and Group B Streptococcal vaginal colonisation before birth, and depression and anxiety postpartum...
2016: BMC Pregnancy and Childbirth
Yoojun Song, Chae-Kwan Lee, Kun-Hyung Kim, Jong-Tae Lee, Chunhui Suh, Se-Yeong Kim, Jeong-Ho Kim, Byung-Chul Son, Dae-Hwan Kim, Sangyoon Lee
This study investigated the concentration of total mercury (THg) in maternal blood, cord blood, and breast milk, and its association with dietary factors. A total of 127 pregnant women in Busan, Korea were recruited. Maternal blood, cord blood, and breast milk were collected at 36 weeks of gestation, at delivery, and at one week after birth, respectively. Information about dietary habits and other factors were obtained from each subject. The mean THg concentrations in maternal blood, cord blood, and breast milk were 3...
2016: Asia Pacific Journal of Clinical Nutrition
B P Foster, T Balassa, T D Benen, M Dominovic, G K Elmadjian, V Florova, M D Fransolet, A Kestlerova, G Kmiecik, I A Kostadinova, C Kyvelidou, M Meggyes, M N Mincheva, L Moro, J Pastuschek, V Spoldi, P Wandernoth, M Weber, B Toth, U R Markert
Extracellular vesicles (EVs) are released from almost all cells and tissues. They are able to transport substances (e.g. proteins, RNA or DNA) at higher concentrations than in their environment and may adhere in a receptor-controlled manner to specific cells or tissues in order to release their content into the respective target structure. Blood contains high concentrations of EVs mainly derived from platelets, and, at a smaller amount, from erythrocytes. The female and male reproductive tracts produce EVs which may be associated with fertility or infertility and are released into body fluids and mucosas of the urogenital organs...
December 2016: Critical Reviews in Clinical Laboratory Sciences
Dilek Doğruel, Gülbin Bingöl, Derya Ufuk Altıntaş, Mustafa Yılmaz, Seval Güneşer Kendirli
BACKGROUND: Although food allergies (FAs) occur most commonly during the 1st year of life, there is limited information available regarding the epidemiology of FAs. In this study, we investigated the incidence of FA and the associated risk factors during the 1st year of life in southeast Turkey. METHODS: This study is a prospective evaluation of 1,377 infants born at the Balcalı Hospital (Çukurova University) and includes four routine follow-up assessments until the age of 1 year...
2016: International Archives of Allergy and Immunology
Jennifer Hellwig
No abstract text is available yet for this article.
October 2015: Nursing for Women's Health
Tomasz Olszowski, Irena Baranowska-Bosiacka, Ewa Rębacz-Maron, Izabela Gutowska, Dominika Jamioł, Adam Prokopowicz, Marta Goschorska, Dariusz Chlubek
The aim of this study was to determine cadmium concentration in mothers' blood, milk, and newborns' blood from Szczecin (Poland) as a result of environmental cadmium exposure and evaluate the correlation (1) between cadmium levels in analyzed matrices, (2) between cadmium and fatty acids in those matrices, and (3) between cadmium and some selected personal variables, such as anthropometric characteristics, mothers' smoking status, and fruit and fish consumption by mothers. The concentration of cadmium in whole blood and milk of mothers and in the umbilical cord blood of newborns was determined by atomic absorption spectrometry with graphite furnace atomization and Zeeman correction...
April 4, 2016: Biological Trace Element Research
Zhuo-Jia Chen, Han-Yan Liu, Ka-Lok Ho, Hong-Bin Huang, Qing Liu, Yu-Bon Man, Michael Hon-Wah Lam, Jun Du, Ming-Hung Wong, Hong-Sheng Wang
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) are attracting more and more attention for the neurodevelopment toxicity effects. We evaluated the concentrations of 15 individual OH-PBDEs and 3 bromophenol (BRP) congeners in 30 mother-newborn paired placenta, breast milk, fetal cord blood, and neonatal urine samples collected from South China. The geometric mean (GM) concentrations of ∑OH-PBDEs were 37.6, 61.3, and 76.8pgg(-1) ww in placenta, breast milk, and cord blood, respectively. The GM concentrations of ∑BRPs were 47...
July 2016: Environmental Research
Fatemeh Abbaszadeh, Zanab Hajizadeh, Mohammad Jahangiri
OBJECTIVES: The best umbilical cord care after birth is a controversial issue. Aim of this research was to compare the effect of topical application of human milk and chlorhexidin on cord separation time in newborns. METHODS: One hundred seventy four neonates attending from hospitals affiliated to Kashan University of Medical Sciences were included. Newborns from birth were randomized to two groups. In group mother's milk, mother will rub her own milk to cord stump two times a day...
January 2016: Pakistan Journal of Medical Sciences Quarterly
Bai-Horng Su, Hsiang-Yu Lin, Fu-Kuei Huang, Ming-Luen Tsai, Yu-Ting Huang
The goal of modern neonatal care of extremely preterm infants is to reduce mortality and long-term neurological impairments. Preterm infants frequently experience cerebral intraventricular or pulmonary hemorrhage, which usually occurs within 72 hours after birth and can lead to long-term neurological sequelae and mortality. These serious hemorrhagic complications are closely related to perinatal hemodynamic changes, including an increase in the afterload on the left ventricle of the heart after the infant is separated from the placenta, and an increased preload from a left-to-right shunt caused by a hemodynamically significant patent ductus arteriosus (PDA)...
February 4, 2016: Pediatrics and Neonatology
Saneea Almas, Jesse Vance, Teresa Baker, Thomas Hale
Multiple Sclerosis (MS) is an autoimmune neurological disease characterized by inflammation of the brain and spinal cord. Relapsing-Remitting MS is characterized by acute attacks followed by remission. Treatment is aimed at halting these attacks; therapy may last for months to years. Because MS disproportionately affects females and commonly begins during the childbearing years, clinicians treat pregnant or nursing MS patients. The intent of this review is to perform an in-depth analysis into the safety of drugs used in breastfeeding women with MS...
2016: Multiple Sclerosis International
Supinda Bunyavanich, Sheryl L Rifas-Shiman, Thomas A Platts-Mills, Lisa Workman, Joanne E Sordillo, Carlos A Camargo, Matthew W Gillman, Diane R Gold, Augusto A Litonjua
BACKGROUND: The role of early-life vitamin D in childhood allergy is controversial. OBJECTIVE: We sought to assess vitamin D exposure in early life by multiple modalities and ascertain its association with childhood allergic rhinitis and allergic sensitization. METHODS: One thousand two hundred forty-eight mother-child pairs from a US prebirth cohort unselected for any disease were studied. Vitamin D exposure was assessed by measures of maternal intake during the first and second trimesters of pregnancy and serum 25-hydroxyvitamin D (25[OH]D) levels in mothers during pregnancy, cord blood, and children at school age (median age, 7...
April 2016: Journal of Allergy and Clinical Immunology
Marijke de Cock, Ilona Quaak, Eva J Sugeng, Juliette Legler, Margot van de Bor
BACKGROUND: The presence of chemicals in the environment is ubiquitous. Human biomonitoring studies have shown that various chemicals can be detected in the majority of the population, including pregnant women. These compounds may pass the placenta, and reach the fetus. This early life exposure in particular may be detrimental as some chemicals may disrupt the endocrine system, which is involved in various processes during development. The LINC study is a prospective birth cohort designed to study associations between early life environmental exposures and child health, including growth and neurodevelopment...
2016: BMC Public Health
Hiroshi Nitta
The goal of the Japan Environment and Children's Study (JECS) is to improve the health and welfare of children and to contribute to better risk management of chemical substances in the environment. The study will examine hypotheses related to reproduction, congenital anomalies, neuropsychiatric development, immunity, metabolism and endocrine system. The hypotheses will be tested for indicative outcomes in combination with exposure to chemicals, as well as confounders and modulators, such as chemical, physical, genetic, social and lifestyle-related factors...
2016: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
Lila B Wollman, Jarl Haggerty, Jason Q Pilarski, Richard B Levine, Ralph F Fregosi
Prenatal nicotine exposure with continued exposure through breast milk over the first week of life (developmental nicotine exposure, DNE) alters the development of brainstem circuits that control breathing. Here, we test the hypothesis that DNE alters the respiratory motor response to endogenous and exogenous acetylcholine (ACh) in neonatal rats. We used the brainstem-spinal cord preparation in the split-bath configuration, and applied drugs to the brainstem compartment while measuring the burst frequency and amplitude of the fourth cervical ventral nerve roots (C4VR), which contain the axons of phrenic motoneurons...
October 2016: Developmental Neurobiology
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