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https://www.readbyqxmd.com/read/28227795/simplified-realistic-human-head-model-for-simulating-tumor-treating-fields-ttfields
#1
Cornelia Wenger, Ze'ev Bomzon, Ricardo Salvador, Peter J Basser, Pedro C Miranda, Cornelia Wenger, Ze'ev Bomzon, Ricardo Salvador, Peter J Basser, Pedro C Miranda, Peter J Basser, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador, Ze'ev Bomzon
Tumor Treating Fields (TTFields) are alternating electric fields in the intermediate frequency range (100-300 kHz) of low-intensity (1-3 V/cm). TTFields are an anti-mitotic treatment against solid tumors, which are approved for Glioblastoma Multiforme (GBM) patients. These electric fields are induced non-invasively by transducer arrays placed directly on the patient's scalp. Cell culture experiments showed that treatment efficacy is dependent on the induced field intensity. In clinical practice, a software called NovoTal(TM) uses head measurements to estimate the optimal array placement to maximize the electric field delivery to the tumor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227744/classification-of-non-weight-bearing-lower-limb-movements-towards-a-potential-treatment-for-phantom-limb-pain-based-on-myoelectric-pattern-recognition
#2
Eva Lendaro, Max Ortiz-Catalan, Eva Lendaro, Max Ortiz-Catalan, Max Ortiz-Catalan, Eva Lendaro
Research in myoelectric pattern recognition (MPR) for the prediction of motor volition has primarily focused on the upper limbs. Recent studies in the lower limbs have mainly concentrated on prosthetic control, while MPR for lower limb rehabilitation purposes has received little attention. In this work we investigated the viability of a MPR system for the prediction of four degrees of freedom controlled in a near natural or physiologically appropriate fashion. We explored three different electrode configurations for acquiring electromyographic (EMG) signals: two targeted (bipolar and monopolar) and one untargeted (electrodes equally spaced axially)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227742/a-computational-model-of-orientation-dependent-activation-of-retinal-ganglion-cells
#3
Timothy Esler, Anthony N Burkitt, David B Grayden, Robert R Kerr, Bahman Tahayori, Hamish Meffin, Timothy Esler, Anthony N Burkitt, David B Grayden, Robert R Kerr, Bahman Tahayori, Hamish Meffin, Anthony N Burkitt, Timothy Esler, Hamish Meffin, David B Grayden, Robert R Kerr, Bahman Tahayori
Currently, a challenge in electrical stimulation for epiretinal prostheses is the avoidance of stimulation of axons of passage in the nerve fiber layer that originate from distant regions of the ganglion cell layer. A computational model of extracellular stimulation that captures the effect of neurite orientation in anisotropic tissue is developed using a modified version of the standard volume conductor model, known as the cellular composite model, embedded in a four layer model of the retina. Simulations are conducted to investigate the interaction of neural tissue orientation, electrode placement, and stimulation pulse duration and amplitude...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227738/tuning-electrical-stimulation-for-thalamic-visual-prosthesis-an-autoencoder-based-approach
#4
Amr Jawwad, Hossam H Abolfotuh, Bassem Abdullah, Hani M K Mahdi, Seif Eldawlatly, Amr Jawwad, Hossam H Abolfotuh, Bassem Abdullah, Hani M K Mahdi, Seif Eldawlatly, Amr Jawwad, Hani M K Mahdi, Bassem Abdullah, Seif Eldawlatly, Hossam H Abolfotuh
Visual prosthesis holds hope of vision restoration for millions with retinal degenerative diseases. Machine learning techniques such as artificial neural networks could help in improving prosthetic devices as they could learn how the brain encodes information and imitate that code. This paper introduces an autoencoder-based approach for tuning thalamic visual prostheses. The objective of the proposed approach is to estimate electrical stimuli that are equivalent to a given natural visual stimulus, in a way such that they both elicit responses that are as similar as possible when introduced to a Lateral Geniculate Nucleus (LGN) population...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227666/advanced-sensors-placement-for-accurate-3d-needle-shape-reconstruction
#5
Pierre-Loup Schaefer, Gregory Chagnon, Alexandre Moreau-Gaudry, Pierre-Loup Schaefer, Gregory Chagnon, Alexandre Moreau-Gaudry, Pierre-Loup Schaefer, Alexandre Moreau-Gaudry, Gregory Chagnon
Needles are tools widely used in minimally invasive surgery. During such procedures the localization of the needle and its tip is a challenging situation because of the needle deformations due to its interactions with tissues. To tackle this problem, instrumented needles with sensors have been currently developed to allow needle reconstruction and tip localization. In conventional surgery this difficulty is overcome by medical imaging. The interest in using an instrumented needle resides in the possible dispense of medical imaging...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227662/towards-synergistic-control-of-hands-on-needle-insertion-with-automated-needle-steering-for-mri-guided-prostate-interventions
#6
Marek Wartenberg, Niravkumar Patel, Gang Li, Gregory S Fischer, Marek Wartenberg, Niravkumar Patel, Gang Li, Gregory S Fischer, Niravkumar Patel, Marek Wartenberg, Gregory S Fischer, Gang Li
A significant hurdle of accurate needle tip placement in percutaneous needle-based prostate interventions is unmodeled needle deflection and tissue deformation during insertion. This paper introduces a robotic platform for developing synergistic, cooperatively controlled needle insertion algorithms decoupled from closed-loop image-guided needle steering. Shared control of the surgical workspace through human-robot synergy creates a balance between the accuracy of robotic autonomy while still providing ultimate control of the procedure to the physician...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227659/toward-robot-assisted-hard-osteolytic-lesion-treatment-using-a-continuum-manipulator
#7
Farshid Alambeigi, Y Wang, Ryan J Murphy, Iulian Iordachita, Mehran Armand, Farshid Alambeigi, Y Wang, Ryan J Murphy, Iulian Iordachita, Mehran Armand, Ryan J Murphy, Y Wang, Iulian Iordachita, Mehran Armand, Farshid Alambeigi
In this paper, we describe the design and fabrication of an actuation unit for controlling a continuum dexterous manipulator (CDM). The actuation unit is attached to a positioning robot and the integrated system provides sufficient dexterity for placement of a proposed flexible cutting tool used for treatment of oseteolysis (bone degradation). Preliminary experiments on simulated osteolytic lesions demonstrated the feasibility of using the novel flexible cutter inside the continuum manipulator. In these experiments, we found an optimal combination of rotational and sweeping speed of the cutter through the lesion...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227592/saw-lc-coupled-resonator-wideband-vco-for-medical-telemetry
#8
Madhav Venkateswaran, Mark Hillig, James E Brown, Paul J Stadnik, Jeffrey A Von Arx, Brian Sutton, Larry J Stotts, Madhav Venkateswaran, Mark Hillig, James E Brown, Paul J Stadnik, Jeffrey A Von Arx, Brian Sutton, Larry J Stotts, Mark Hillig, Jeffrey A Von Arx, Madhav Venkateswaran, Brian Sutton, James E Brown, Paul J Stadnik, Larry J Stotts
Wireless links with implantable devices can help in real-time monitoring of symptoms, irregularities, implanted device efficacy and their reconfiguration. We present the design of a low-power wideband voltage controlled oscillator (VCO) to facilitate implantable wireless telemetry. A coupled SAW-LC resonator design combines high Q and spectral purity of a SAW element and tunability of an LC-tank. The designed 2.7 MHz bandwidth VCO is suitable for full duplex communication protocols in the MedRadio band with frequency agility and higher duty cycles, in conformance with FCC regulations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227450/using-multiple-placements-of-accelerometers-to-measure-cardiovascular-pulse-transit-times
#9
Natalie Kurgan Canino, Ruisheng Rick Wang, Charles J Robinson, Natalie Kurgan Canino, Ruisheng Wang, Charles J Robinson, Natalie Kurgan Canino, Charles J Robinson, Ruisheng Rick Wang
To measure pulse transit times (PTT) and calculate pulse wave velocities (PWV), tri-axial and uniaxial accelerometers were placed in groups of 2 to 4 over the manubrium, xiphoid process, forehead, wrist and ankle, and/or over the carotid, femoral, and posterior auricular arteries in 11 consented supine subjects. Signals were sampled at 1 kHz and filtered. Radial vectors were calculated from the tri-axial measurements. A 3-lead ECG was simultaneously collected over the same 180 s window, as well as respiratory rate...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227193/double-sensor-complementary-placement-method-to-reduce-motion-artifacts-in-ppg-using-fast-independent-component-analysis
#10
Frank P-W Lo, Max Q-H Meng, Frank P-W Lo, Max Q-H Meng, Max Q H Meng, Frank P W Lo
A novel sensor placement method for better removal of motion artifacts (MA) from photoplethysmography (PPG) signal using Fast Independent Component Analysis (ICA) is proposed in this paper. The method enhances the determination of pulse transit time (PTT) of PPG signals. The design makes use of double reflectance mode based PPG probes, which are placed complementary to each other and on the two sides of a single finger. Furthermore, a novel indicator denoted as Separating Factor is proposed as well. It helps evaluating the performance of ICA with different sensors configuration...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227179/influence-of-electrode-configuration-on-the-electric-field-distribution-during-transcutaneous-spinal-direct-current-stimulation-of-the-cervical-spine
#11
Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, Mamede A de Carvalho, Pedro C Miranda, Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, Mamede A de Carvalho, Pedro C Miranda, Sofia R Fernandes, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador, Mamede A de Carvalho
Transcutaneous spinal direct current stimulation (tsDCS) is a recent technique with promising neuromodulatory effects on spinal neuronal circuitry. The main objective of the present study was to perform a finite element analysis of the electric field distribution in tsDCS in the cervical spine region, with varying electrode configurations and geometry. A computational model of a human trunk was generated with nine tissue meshes. Three electrode configurations were tested: A) rectangular saline-soaked sponge target and return electrodes placed over C3 and T3 spinous processes, respectively; B1) circular saline-soaked sponge target and return electrodes placed over C7 spinous process and right deltoid muscle, respectively; B2) same configuration as B1, considering circular shaped electrodes with sponge and rubber layers and a small circular connector on the top surface...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227158/interventional-placement-of-thin-coil-shaped-implants-powered-wirelessly-for-monitoring-vital-signals-and-controlling-abnormal-activities-by-electro-stimulation
#12
Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Masanobu Honda, Hidetoshi Ohta, Makoto Takamiya
Various types of implants are being commonly used for monitoring vital signals and controlling the critically ill patient's condition such as arrhythmia, sick sinus syndrome, etc. For implanting these medical devices under the skin, surgery is inevitable. These days many patients are more willing to accept interventional therapies that are less invasive, especially inserting a catheter into a blood vessel or endoscopy through a natural orifice. To be able to use interventional therapy for implanting medical devices, they will need to be small enough to fit them through a catheter or the forceps channel of an endoscope...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227030/sparse-shape-model-for-fibular-transfer-planning-in-mandibular-reconstruction
#13
Riho Kawasaki, Megumi Nakao, Yuichiro Imai, Nobuhiro Ueda, Toshihide Hatanaka, Mao Shiba, Tadaaki Kirita, Tetsuya Matsuda, Riho Kawasaki, Megumi Nakao, Yuichiro Imai, Nobuhiro Ueda, Toshihide Hatanaka, Mao Shiba, Tadaaki Kirita, Tetsuya Matsuda, Nobuhiro Ueda, Yuichiro Imai, Riho Kawasaki, Toshihide Hatanaka, Megumi Nakao, Tadaaki Kirita, Mao Shiba, Tetsuya Matsuda
In this paper, we propose an automated preoperative planning method that estimates a plan fitted to the data of a new patient using a planned dataset of previous patients. Although mandibular reconstruction with fibular segments needs preoperative planning for the precise placement of segments, recent interactive planning software cannot secure objectivity of the planning and time-consuming trial-and-error processes are required. The proposed method employs sparse shape modeling; in this modeling, we select a subset of the data from a prepared preoperative planning dataset to make an example or instance of reconstruction via a linear combination of the data...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227024/sensor-data-quality-processing-for-vital-signs-with-opportunistic-ambient-sensing
#14
Ibrahim Sadek, Jit Biswas, Zhu Yongwei, Zhang Haihong, Jayachandran Maniyeri, Chen Zhihao, Teo Ju Teng, Ng Soon Huat, Mounir Mokhtari, Ibrahim Sadek, Jit Biswas, Zhu Yongwei, Zhang Haihong, Jayachandran Maniyeri, Chen Zhihao, Teo Ju Teng, Ng Soon Huat, Mounir Mokhtari
Opportunistic ambient sensing involves placement of sensors appropriately so that intermittent contact can be made unobtrusively for gathering physiological signals for vital signs. In this paper, we discuss the results of our quality processing system used to extract heart rate from ballisto-cardiogram signals obtained from a micro-bending fiber optic sensor pressure mat. Visual inspection is used to label data into informative and non-informative classes based on their heart rate information. Five classifiers are employed for the classification process, i...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226855/on-comparing-in-vivo-intracranial-recordings-in-non-human-primates-to-predictions-of-optimized-transcranial-electrical-stimulation
#15
Abhishek Datta, Matthew R Krause, Praveen K Pilly, Jaehoon Choe, Theodoras P Zanos, Chris Thomas, Christopher C Pack, Abhishek Datta, Matthew R Krause, Praveen K Pilly, Jaehoon Choe, Theodoras P Zanos, Chris Thomas, Christopher C Pack, Jaehoon Choe, Chris Thomas, Theodoros P Zanos, Abhishek Datta, Praveen K Pilly, Christopher C Pack, Matthew R Krause
Transcranial electrical stimulation (tES) can be optimized to achieve maximal current flow at desired brain regions. The aim of this study was to characterize electric field magnitudes generated by tES optimization and to compare them to experimentally induced values as determined by data from intracranial electrodes. Local field potentials were recorded from two monkeys with implanted multi-site intracranial Utah arrays during transcranial direct current stimulation (tDCS), and the neural effect predictions obtained from optimized electrode placement were assessed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226838/realistic-motor-unit-placement-in-a-cylindrical-hd-semg-generation-model
#16
Vincent Carriou, Jeremy Laforet, Sofiane Boudaoud, Mariam Al Harrach, Vincent Carriou, Jeremy Laforet, Sofiane Boudaoud, Mariam Al Harrach, Jeremy Laforet, Sofiane Boudaoud, Vincent Carriou, Mariam Al Harrach
The aim of this work is to assess an automatic optimized algorithm for the positioning of the Motor Units (MUs) within a multilayered cylindrical High Density surface EMG (HD-sEMG) generation model representing a skeletal muscle. The multilayered cylinder is composed of three layers: muscle, adipose and skin tissues. For this purpose, two different algorithms will be compared: an unconstrained random and a Mitchell's Best Candidate (MBC) placements, both with uniform distribution for the MUs positions. These algorithms will then be compared by their fiber density within the muscle and by using a classical amplitude descriptor, the Root-Mean-Square (RMS) amplitude value obtained from 64 HD-sEMG signals recorded by an 8×8 electrode grid of circular electrode during one contraction at 70% Maximum Voluntary Contraction (MVC) in both simulation and experimental conditions for the Biceps Brachii (BB) muscle...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226806/multistep-model-for-predicting-upper-limb-3d-isometric-force-application-from-pre-movement-electrocorticographic-features
#17
Jing Wu, Benjamin R Shuman, Bingni W Brunton, Katherine M Steele, Jared D Olson, Rajesh P N Rao, Jeffrey G Ojemann, Jing Wu, Benjamin R Shuman, Bingni W Brunton, Katherine M Steele, Jared D Olson, Rajesh P N Rao, Jeffrey G Ojemann, Rajesh P N Rao, Jared D Olson, Benjamin R Shuman, Katherine M Steele, Jing Wu, Jeffrey G Ojemann, Bingni W Brunton
Neural correlates of movement planning onset and direction may be present in human electrocorticography in the signal dynamics of both motor and non-motor cortical regions. We use a three-stage model of jPCA reduced-rank hidden Markov model (jPCA-RR-HMM), regularized shrunken-centroid discriminant analysis (RDA), and LASSO regression to extract direction-sensitive planning information and movement onset in an upper-limb 3D isometric force task in a human subject. This mode achieves a relatively high true positive force-onset prediction rate of 60% within 250ms, and an above-chance 36% accuracy (17% chance) in predicting one of six planned 3D directions of isometric force using pre-movement signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226705/non-rigid-mri-ct-registration-for-effective-planning-of-prostate-brachytherapy
#18
I Hamdan, G Dardenne, J Bert, D Visvikis, I Hamdan, G Dardenne, J Bert, D Visvikis, I Hamdan, G Dardenne, J Bert, D Visvikis
Prostate brachytherapy is an intraoperative radiotherapy technique for irradiating prostate tumors by placing radioactive sources inside the prostate. CT image is used to calculate a personalized dose distribution (PDD) while the MRI is used to visualize the tumor and the organs at risk. Therefore, a registration of preoperative MRI and CT is essential since it could improve the overall precision of the treatment planning, the placement of radioactive sources inside the prostate as well as the visualization of the dose distribution with respect to the tumor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226671/connectivity-maps-of-different-types-of-epileptogenic-patterns
#19
Hoda Rajaei, Mercedes Cabrerizo, Panuwat Janwattanapong, Alberto Pinzon-Ardila, Sergio Gonzalez-Arias, Malek Adjouadi, Hoda Rajaei, Mercedes Cabrerizo, Panuwat Janwattanapong, Alberto Pinzon-Ardila, Sergio Gonzalez-Arias, Malek Adjouadi, Sergio Gonzalez-Arias, Malek Adjouadi, Hoda Rajaei, Panuwat Janwattanapong, Mercedes Cabrerizo, Alberto Pinzon-Ardila
EEG functional connectivity maps, showing the interactions between brain areas in context to the placement of electrodes, were used for the investigation and comparison of three different types of epileptiform activity defined as single spike, spike followed by slow wave and repetitive spike. A nonlinear data-driven method was used to extract connectivity matrices that helped to identify network synchronization based on the number of connections for all brain regions, as represented by the 10-20 EEG system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226545/a-novel-catheter-guidance-algorithm-for-localization-of-atrial-fibrillation-rotor-and-focal-sources
#20
Anthony J Salmin, Prasanth Ganesan, Kristina E Shillieto, Elizabeth M Cherry, David T Huang, Arkady M Pertsov, Behnaz Ghoraani, Anthony J Salmin, Prasanth Ganesan, Kristina E Shillieto, Elizabeth M Cherry, David T Huang, Arkady M Pertsov, Behnaz Ghoraani, Arkady M Pertsov, Behnaz Ghoraani, Anthony J Salmin, Kristina E Shillieto, Elizabeth M Cherry, Prasanth Ganesan, David T Huang
Locating atrial fibrillation (AF) focal and rotor sources can help improve target ablation therapy for AF. However, it remains unclear how to use the information provided by multi-polar diagnostic catheters (MPDC) to locate AF sources. Our aim was to develop a catheter-guidance algorithm to locate AF focal and rotor sources using a conventional MPDC. We simulated a 10 cm × 10 cm atrial tissue with focal and rotor sources using the Nygren et al. ionic model. We modeled a Lasso MPDC with 20-unipole electrodes placed with a spacing of 4...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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