I Abdalla, L Ignacio, F Vaida, Mei-Hsu, A Awan, A Jani, C Mamo, R R Weichselbaum, S Vijayakumar
The limiting factor for radiation (RT) dose-escalation is normal tissue toxicity. In dose-escalation studies, it is important to determine the factors associated with toxicity and the length of follow-up period after which a particular RT dose is considered safe. We analyzed 449 prostate cancer patients treated with RT at our institution and followed for a median of 27 months. Genitourinary (GU) and gastrointerological (GI) complications were graded and analyzed using three different statistical models. Univariate and multivariate analyses were conducted for factors associated with toxicity...
2002: Prostate Cancer and Prostatic Diseases