Yang Guo, Shujin Li, Zhan Shi, Bingchen Chen, Ziang Wan, Peng Yu, Boan Zheng, Wenjing Gong, Rui Chai, Shiliang Tu, Hang Yuan
BACKGROUND: EEPD1 is vital in homologous recombination, while its role in cancer remains unclear. METHODS: We performed multiple pan-cancer analyses of EEPD1 with bioinformatics methods, such as gene expression, gene alterations, Prognosis and enrichment analysis, tumor microenvironment, immune cell infiltration, TMB, MSI, immunotherapy, co-expression of genes, and drug resistance. Finally, RT-qPCR, EdU, and transwell assays helped investigate the impact of EEPD1 on CRC cells...
April 15, 2024: Heliyon