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Severe mental illness

Kai G Kahl, Michael Deuschle, Brendon Stubbs, Ulrich Schweiger
Background Severe mental illnesses (SMIs), i.e. major depression, schizophrenia and bipolar disorder, are associated with an elevated risk for the development of type-2 diabetes mellitus and cardiovascular disorders. Several factors have been associated with increased cardiometabolic morbidity and mortality in SMI, including lifestyle factors (smoking, inactivity, unhealthy diet), endocrine and immunologic alterations; however, the underlying mechanisms remain to be fully uncovered. It is now well accepted that visceral adipose tissue (VAT) promotes the development of cardiometabolic disorders, at least in part by inflammatory and metabolic functions...
March 16, 2018: Hormone Molecular Biology and Clinical Investigation
David Veale
In 2012, the coalition government introduced the legal right for National Health Service (NHS) patients in England to choose their mental healthcare provider for out-patient treatment. This was a significant step towards parity of care between mental and physical ill health, and NHS Improvement and NHS England have provided sensible guidance on its implementation. However, several factors prevent the system from working as it was intended: lack of awareness of the principle of patient choice for out-patient treatment; complacency from some trusts and commissioners; mental health trusts operating outside the e-referrals system; misuse of care pathways; lack of direct access by many general practitioners for out-of-area referrals; and delays in authorisation for funding...
April 2018: BJPsych Bulletin
Germano Orrù, Mauro Giovanni Carta
Background: Bipolar Disorder (BD), along with depression and schizophrenia, is one of the most serious mental illnesses, and one of the top 20 causes of severe impairment in everyday life. Recent molecular studies, using both traditional approaches and new procedures such as Whole-Genome Sequencing (WGS), have suggested that genetic factors could significantly contribute to the development of BD, with heritability estimates of up to 85%. However, it is assumed that BD is a multigenic and multifactorial illness with environmental factors that strongly contribute to disease development/progression, which means that progress in genetic knowledge of BD might be difficult to interpret in clinical practice...
2018: Clinical Practice and Epidemiology in Mental Health: CP & EMH
Jacquie White, Joanne Lucas, Louise Swift, Garry R Barton, Harriet Johnson, Lisa Irvine, Gabriel Abotsie, Martin Jones, Richard J Gray
OBJECTIVE: This study tested the effectiveness of a nurse-delivered health check with the Health Improvement Profile (HIP), which takes approximately 1.5 hours to complete and code, for persons with severe mental illness. METHODS: A single-blind, cluster-randomized controlled trial was conducted in England to test whether health checks improved the general medical well-being of persons with severe mental illness at 12-month follow-up. RESULTS: Sixty nurses were randomly assigned to the HIP group or the treatment-as-usual group...
March 15, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
Joseph El-Khoury, Rassil Ghazzaoui, Amanda Ahmad
The recognition of mental health needs in developing countries is growing in parallel with increased public awareness of and reduced stigma toward mental illness. With resources still limited in these countries, creating economically viable health care models is essential. These models are often adapted from already established and tested systems in industrialized nations. The Psychosis Recovery Outreach Program (PROP) at the American University of Beirut is an initiative that exemplifies the global transfer of knowledge, experience, and skills...
March 15, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
Amelia Gulliver, Alyssa R Morse, Niah Wilson, Ginny Sargent, Michelle Banfield
Partners in Recovery (PIR) is a nation-wide Australian program designed to improve coordinated care for people with severe and persistent mental health problems. This study evaluated PIR's effectiveness for individual and system-level outcomes. A total of 25 PIR participants (male = 7, female = 15, not stated = 3) provided data for the evaluation of the program across six community mental health service providers in Canberra, Australia. Individual-level measures included quality of life, social inclusion, and perceptions of recovery...
March 5, 2018: Evaluation and Program Planning
Divya Ballal, Janardhana Navaneetham
BACKGROUND: Children of parents with mental illness are not routinely included in psychoeducational and supportive family interventions provided by adult mental health systems. The family, therefore, is an important and, sometimes, the only source of information and support for them. AIM: To understand the experiences of well parents in talking to their children about parental mental illness. METHOD: This article presents the findings of a qualitative study of the experiences of well parents in talking to their children about parental mental illness...
March 1, 2018: International Journal of Social Psychiatry
Vibeke Bliksted, Chris Frith, Poul Videbech, Birgitte Fagerlund, Charlotte Emborg, Arndis Simonsen, Andreas Roepstorff, Daniel Campbell-Meiklejohn
Background: Historically, research investigating neural correlates of mentalizing deficits in schizophrenia has focused on patients who have been ill for several years with lengthy exposure to medication. Little is known about the neural and behavioral presentations of theory-of-mind deficits in schizophrenia, shortly after the first episode of psychosis. Methods: We investigated social cognition in 17 recently diagnosed first-episode schizophrenia (FES) patients with little or no exposure to antipsychotic medication and 1:1 matched healthy controls...
March 9, 2018: Schizophrenia Bulletin
Qiong Wu, Christina Dalman, Håkan Karlsson, Glyn Lewis, David P J Osborn, Renee Gardner, Joseph F Hayes
Background: Mounting evidence implicates early life and prenatal immune disturbances in the etiology of severe mental illnesses. Asthma is a common illness associated with chronic aberrant immune responses. We aimed to determine if asthma in childhood and parents is associated with bipolar and schizophrenia spectrum disorders. Methods: A cohort study including all children born in Sweden 1973-1995 (N > 2 million) assessing associations between childhood hospitalization for asthma, parental asthma during and pre-pregnancy, and subsequent bipolar and schizophrenia spectrum disorders...
March 9, 2018: Schizophrenia Bulletin
Patrick Lombardo, Wayne Jones, Liangliang Wang, Xin Shen, Elliot M Goldner
BACKGROUND: A self-reported life satisfaction question is routinely used as an indicator of societal well-being. Several studies support that mental illness is an important determinant for life satisfaction and improvement of mental healthcare access therefore could have beneficial effects on a population's life satisfaction. However, only a few studies report the relationship between subjective mental health and life satisfaction. Subjective mental health is a broader concept than the presence or absence of psychopathology...
March 12, 2018: BMC Public Health
Buranee Kanchanatawan, Sira Sriswasdi, Supaksorn Thika, Sunee Sirivichayakul, André F Carvalho, Michel Geffard, Marta Kubera, Michael Maes
Deficit schizophrenia is characterized by neurocognitive impairments and changes in the patterning of IgA/IgM responses to plasma tryptophan catabolites (TRYCATs). In the current study, supervised pattern recognition methods, including logistic regression analysis (LRA), Support Vector Machine (SVM), and Soft Independent Modeling of Class Analogy (SIMCA), were used to examine whether deficit schizophrenia is a discrete diagnostic class with respect to Consortium To Establish a Registry for Alzheimer's disease (CERAD) and Cambridge Neuropsychological Test Automated Battery (CANTAB) tests and IgA/IgM responses to noxious (NOX) and generally more protective (PRO) TRYCATs...
March 11, 2018: Metabolic Brain Disease
O Somasundaram, Ponnudurai Ratnaraj
Period of Custodial Care Only: The magnificent "Institute of Mental Health" has its history almost from 1795 when the East India company appointed Surgeon Valentine Conolly to be in charge of a "House for accommodating persons of unsound mind." After a few transitions, backed by a government order for the construction of a lunatic asylum in a 66 1/2 acre site, the asylum started functioning from 1871. The period of about six decades from its inception could be referred to as "the period of custodial care...
February 2018: Indian Journal of Psychiatry
Ania Justo, Alicia Risso, Andrew Moskowitz, Anabel Gonzalez
This article describes the conclusions of an investigation done with 120 Spanish patients: the finding of a new psychopathological profile within a subgroup of patients suffering from schizophrenia. The patients were evaluated through different questionnaires about sociodemographic data, traumatic events, the severity index (both clinical and psychopathological), self-esteem and consciousness of the illness. From the scores obtained on a scale of dissociative experiences, they were classified into two groups: high dissociative symptomatology or HD, and low dissociative symptomatology or LD...
March 7, 2018: Schizophrenia Research
Sarah Toner, Megan Cassidy, Agnes Chevalier, Aida Farreny, Monica Leverton, Mariana Pinto da Costa, Stefan Priebe
BACKGROUND: Befriending has become a widely used method for tackling social isolation in individuals with severe mental illness (SMI), and evidence exists to support its effectiveness. However, patient preferences for befriending remain unclear. We aimed to determine whether patients with SMI want a volunteer befriender and, if so, the volunteer characteristics and character of the relationship they would prefer. METHODS: A survey of outpatients was conducted across London-based community mental health teams, for individuals diagnosed with affective or psychotic disorders...
March 9, 2018: BMC Psychiatry
Petter Andreas Ringen, Ann Faerden, Bjørnar Antonsen, Ragnhild S Falk, Asgeir Mamen, Eline B Rognli, Dag K Solberg, Ole A Andreassen, Egil W Martinsen
PURPOSE: Cardiovascular diseases are a major cause for the markedly reduced life expectancy in people with severe mental illness (SMI). Hospital departments should provide adequate prevention of cardiometabolic risk by optimizing prevention and treatment. Characteristics of cardiometabolic risk factors in inpatients are still not well known. We aimed to describe the status of cardiometabolic risk factors in inpatients with SMI and identify associations with psychiatric status and treatment...
March 9, 2018: Nordic Journal of Psychiatry
Magdalena Elcoro, Martín Agrest
The concept of "recovery" is still controversial as to what its principal components/dimensions are. From the perspective of a mental health professional, recovery is related to a clinical improvement and to a higher functioning. However, from a users' perspective, its major component is related to hope and having a meaningful life. The present paper analyses recovery by studying English and Spanish scales designed to measure recovery. A total of 44 recovery scales were found, of which only 19 had been made public, evaluated personal recovery from a users' perspective, used a Likert scale for all items and could be adapted to different contexts...
November 2017: Vertex: Revista Argentina de Psiquiatriá
David Roe, Amit Yamin
Research around the world has consistently shown that people with serious mental illness (SMI) are often subject to stronglyheld stigmatizing attitudes held by others in society (e.g., dangerousness, incompetence, inability to work). As a result, people with SMI often experience "internalized stigma" or "self-stigma" which reflects the process by which stigmatizing attitudes are internalized, leading to the loss of previously held or hoped for identities (e.g., self as student, self as worker, self as parent, etc...
September 2017: Vertex: Revista Argentina de Psiquiatriá
Andrea Finaret, Paula Garber-Epstein
In recent decades there have been changes in the mental health feld that have also influenced the therapist-client relationship, which is seen as an essential element in the processes of recovery. Our purpose is to present a model of work reflected in therapeutic relationships in the feld of rehabilitation (RTR) that is guided by the principles of recovery. Therapeutic relationships are considered as a means through which it is possible to increase commitment and adherence of people to therapy and also participation in treatment and rehabilitation programs...
September 2017: Vertex: Revista Argentina de Psiquiatriá
Pablo M Gabay, Mónica Fernández Bruno
The rehabilitation of severely mentally-ill patients and their return to the community are related to historical progress. Their potential of achieving these goals is higher or lower depending on the presence of more or less stigma attached to their condition. Watts and Bennett have divided psychiatric rehabilitation into three phases: Phase 1: Very little was done because there was not much to be done. Patients were rejected and received mistreatment. Phase 2: Their vulnerability was admitted and protection was given to the disabled; services were provided by charity and voluntary religious institutions; there was no clear distinction between illness and poverty...
September 2017: Vertex: Revista Argentina de Psiquiatriá
S Pathare, A Brazinova, I Levav
AIM: Treatment gap refers to the percentage of individuals who require treatment in a country or a defined community but do not receive it due to various reasons. There is widespread acceptance of 'treatment gap' as a measure of unmet needs in mental health. However, the term 'treatment' carries a medical connotation and implies biomedical treatment (or lack of it) of mental illness and is often interpreted by policymakers, planners and researchers, as well as by non-professional stakeholders as exclusively referring to curative clinical psychiatric interventions...
March 9, 2018: Epidemiology and Psychiatric Sciences
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