keyword
MENU ▼
Read by QxMD icon Read
search

skullcap

keyword
https://www.readbyqxmd.com/read/29733905/bouffant-vs-skull-cap-and-impact-on-surgical-site-infection-does-operating-room-headgear-really-matter
#1
Shanu N Kothari, Madeline J Anderson, Andrew J Borgert, Kara J Kallies, Todd J Kowalski
BACKGROUND: The American College of Surgeons (ACS) guidelines indicate that skullcaps are acceptable, while the Association of periOperative Registered Nurses (AORN) recommends bouffant caps. However, no scientific evidence has shown a significant advantage in surgical site infection (SSI) reduction with either cap. The objective of this study was to determine the influence of surgical cap choice on SSIs. STUDY DESIGN: Data from a previously published prospective randomized trial on the impact of hair clipping on SSI were analyzed...
May 4, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29619433/increased-apoptosis-skull-of-pups-born-to-toxoplasma-gondii-infected-mice-associated-with-increased-expression-of-interferon-gamma-but-not-tumor-necrosis-factor-alfa
#2
Lucia Tri Suwanti, Mufasirin
Bacground: Toxoplasma gondii is an intracellular obligate protozoan parasite that infects most warm-blooded animals including humans. It can cause congenital infection with clinical symptoms ranging from mild to severe including microcephaly. At the cellular level, infection T. gondii causes apoptosis in some tissues and it is induced by proinflammatory cytokines, such as IFN-γ and TNF-α. The purpose of this study is to determine the role of proinflammatory cytokines (TNF-α and IFN-γ) to apoptosis skull of newborn from T...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29331689/baicalin-inhibits-pressure-overload-induced-cardiac-fibrosis-through-regulating-ampk-tgf-%C3%AE-smads-signaling-pathway
#3
Yichuan Xiao, Jiantao Ye, Ying Zhou, Junjun Huang, Xiawen Liu, Biyun Huang, Liu Zhu, Bo Wu, Genshui Zhang, Yi Cai
AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic pathways. It has been shown that activation of AMPK could inhibit fibroblast proliferation and extracellular matrix (ECM) accumulation, thereby suppressing cardiac fibrosis. Baicalin, the major component found in skullcap, possesses multiple protective effects on the cardiovascular system. However, little is known about the effect of baicalin on cardiac fibrosis and the molecular mechanism by which baicalin exerts its anti-fibrotic effects has not been investigated...
February 15, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29168225/gaba-modulating-phytomedicines-for-anxiety-a-systematic-review-of-preclinical-and-clinical-evidence
#4
REVIEW
Karen Savage, Joseph Firth, Con Stough, Jerome Sarris
Anxiety disorders are chronic and functionally disabling conditions with high psychological stress, characterised by cognitive symptoms of excessive worry and focus difficulties and physiological symptoms such as muscle tension and insomnia. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter within the central nervous system and is a key target of pharmacotherapies in the treatment of anxiety. Although current pharmaceutical treatments are often efficacious, they may cause undesirable side effects including cognitive decrements and withdrawal symptoms...
January 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29161468/the-relationship-between-endogenous-%C3%AE-glucuronidase-activity-and-biologically-active-flavones-aglycone-contents-in-hairy-roots-of-baikal-skullcap
#5
Varvara S Dikaya, Aleksandra I Solovyeva, Roman A Sidorov, Pavel A Solovyev, Anna Yu Stepanova
Here, we examine the relationship between contents of principal flavones in hairy roots of Scutellaria baicalensis with the activity of the β-glucuronidase (sGUS) enzyme during a culturing cycle. Using RP-HPLC, we show that the highest contents of aglycones, baicalin and wogonin is observed at the growth days 8, 14, and 71 and reach 45, 41, and 62% (based on the total weight of hairy roots of the Baikal skullcap), correspondingly. Their accumulation is accompanied by increase of the sGUS activity, which we determined fluorometrically...
February 2018: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/29143798/skullcap-scutellaria-baicalensis-hexane-fraction-inhibits-the-permeation-of-ovalbumin-and-regulates-th1-2-immune-responses
#6
Sun Young Jung, So-Young Lee, Dae Woon Choi, Hye-Jeong See, Da-Ae Kwon, Jeong-Ryong Do, Dong-Hwa Shon, Hee Soon Shin
Skullcap ( Scutellaria baicalensis ) is well known for its anti-inflammatory and anti-allergic effects. In our previous study, we found that skullcap could inhibit allergen permeation and regulate Th1/2 immune balance. To reveal the key fractions and components of skullcap, we fractionated skullcap extract into five fractions: hexane, chloroform, ethyl acetate, butanol, and water fraction. Among these fractions, the hexane fraction significantly suppressed the production of Th2-mediated cytokines (Interleukin (IL)-4, 5, 10 and 13) and increased Th1-mediated cytokines (Interferon (IFN)-γ and IL-12)...
October 28, 2017: Nutrients
https://www.readbyqxmd.com/read/28880166/catheter-hydrophone-aberration-correction-for-transcranial-histotripsy-treatment-of-intracerebral-hemorrhage-proof-of-concept
#7
Tyler Gerhardson, Jonathan R Sukovich, Aditya S Pandey, Timothy L Hall, Charles A Cain, Zhen Xu
Histotripsy is a minimally invasive ultrasound therapy that has shown rapid liquefaction of blood clots through human skullcaps in an in vitro intracerebral hemorrhage model. However, the efficiency of these treatments can be compromised if the skull-induced aberrations are uncorrected. We have developed a catheter hydrophone which can perform aberration correction (AC) and drain the liquefied clot following histotripsy treatment. Histotripsy pulses were delivered through an excised human skullcap using a 256-element, 500-kHz hemisphere array transducer with a 15-cm focal distance...
November 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28716432/effect-of-frequency-and-focal-spacing-on-transcranial-histotripsy-clot-liquefaction-using-electronic-focal-steering
#8
Tyler Gerhardson, Jonathan R Sukovich, Aditya S Pandey, Timothy L Hall, Charles A Cain, Zhen Xu
This in vitro study investigated the effects of ultrasound frequency and focal spacing on blood clot liquefaction via transcranial histotripsy. Histotripsy pulses were delivered using two 256-element hemispherical transducers of different frequency (250 and 500 kHz) with 30-cm aperture diameters. A 4-cm diameter spherical volume of in vitro blood clot was treated through 3 excised human skullcaps by electronically steering the focus with frequency proportional focal spacing: λ/2, 2 λ/3 and λ with 50 pulses per location...
October 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28658334/customized-acrylic-implants-for-reconstruction-of-extensive-skull-defects-an-exception-approach-for-selected-patients
#9
Rafael Denadai Pigozzi DA Silva, Cesar Augusto Raposo-Amaral, Marcelo Campos Guidi, Cassio Eduardo Raposo-Amaral, Celso Luiz Buzzo
Objective: to present our experience in the surgical treatment of extensive skullcap defects with customized acrylic implants. Methods: we conducted a retrospective analysis of patients with extensive skull defects undergoing acrylic cranioplasties between 2004 and 2013. We carefully selected all patients and classified surgical results based on three scales (craniofacial esthetics, improvement of facial symmetry and need for additional surgery). Results: fifteen patients underwent cranioplasty with intraoperative acrylic implants, whether manually customized (46...
March 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28573603/influence-of-culture-medium-composition-and-light-conditions-on-the-accumulation-of-bioactive-compounds-in-shoot-cultures-of-scutellaria-lateriflora-l-american-skullcap-grown-in-vitro
#10
Beata Kawka, Inga Kwiecień, Halina Ekiert
Methanolic extracts from in vitro grown Scutellaria lateriflora shoots cultured on five Murashige and Skoog (MS) medium variants supplemented with different combinations of 6-benzylaminopurine (BAP) and α-naphthaleneacetic acid (NAA) under different light conditions (monochromatic light, white light and no light) were analysed by HPLC for three groups of metabolites: flavonoids (26 compounds), phenolic acids and their precursors (19+2) and phenylethanoid glycosides (2). The analyses revealed the presence of baicalein, baicalin, wogonin, wogonoside, 3,4-dihydroxyphenylacetic acid and verbascoside...
December 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28284428/distribution-patterns-of-the-contents-of-five-biologically-activate-ingredients-in-the-root-of-scutellaria-baicalensis
#11
Rong-Xiu Liu, Guo-Hu Song, Pei-Gen Wu, Xue-Wen Zhang, Hui-Juan Hu, Jia Liu, Xiao-Su Miao, Zhi-Yan Hou, Wen-Quan Wang, Sheng-Li Wei
As an important herbaceous plant, Scutellaria baicalensis Georgi (Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types, "Ku Qin" (WXR) and "Tiao Qin" (TST). Moreover, TST is also divided into different grades according to the diameter of roots. To explore the distribution patterns of the contents of five biologically activate ingredients (FBAI), we used six-year-old cultivated S. baicalensis and analyzed its growth characteristics as well as the quality difference among different types and diameters in roots...
February 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28274529/japanese-herbal-medicine-induced-pneumonitis-a-review-of-73-patients
#12
Yasunori Enomoto, Yutaro Nakamura, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Takafumi Suda
BACKGROUND: The number of reports concerning Japanese herbal medicine (JHM)-induced pneumonitis has increased. However, comprehensive data are lacking in this regard, and the clinical characteristics of the disease remain unclear. METHODS: A literature review was performed using PubMed and Ichushi-Web-the database of the Japan Medical Abstracts Society-to identify articles published between 1996 and 2015 describing patients with JHM-induced pneumonitis. The final cohort included 73 patients in 59 articles (7 in English; 52 in Japanese)...
March 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28259249/anti-tumor-activity-of-wogonin-an-extract-from-scutellaria-baicalensis-through-regulating-different-signaling-pathways
#13
REVIEW
Do Luong Huynh, Neelesh Sharma, Amit Kumar Singh, Simrinder Singh Sodhi, Jiao-Jiao Zhang, Raj Kumar Mongre, Mrinmoy Ghosh, Nameun Kim, Yang Ho Park, Dong Kee Jeong
Wogonin is a plant flavonoid compound extracted from Scutellaria baicalensis (Huang-Qin or Chinese skullcap) and has been studied thoroughly by many researchers till date for its anti-viral, anti-oxidant, anti-cancerous and neuro-protective properties. Numerous experiments conducted in vitro and in vivo have demonstrated wogonin's excellent tumor inhibitory properties. The anti-cancer mechanism of wogonin has been ascribed to modulation of various cell signaling pathways, including serine-threonine kinase Akt (also known as protein kinase B) and AMP-activated protein kinase (AMPK) pathways, p53-dependent/independent apoptosis, and inhibition of telomerase activity...
January 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/27814566/baicalin-a-natural-lsd1-inhibitor
#14
Yi-Chao Zheng, Dan-Dan Shen, Meng Ren, Xue-Qi Liu, Zhi-Ru Wang, Ying Liu, Qian-Na Zhang, Li-Juan Zhao, Li-Jie Zhao, Jin-Lian Ma, Bin Yu, Hong-Min Liu
Baicalin is one of the active ingredients in the skullcap, with a variety of pharmacological effects, such as blood pressure reduction, sedation, liver-protection, gallbladder-protection, anti-bacteria, and anti-inflammation. In our study, baicalin was first characterized as a LSD1 inhibitor with an IC50 of 3.01μM and showed strong LSD1 inhibitory effect in cells. Baicalin may serve as a template for designing flavone-based LSD1 inhibitors.
December 2016: Bioorganic Chemistry
https://www.readbyqxmd.com/read/27790646/the-extraction-anticancer-effect-bioavailability-and-nanotechnology-of-baicalin
#15
Ondrea A Moore, Ying Gao, Allen Y Chen, Ross Brittain, Yi Charlie Chen
The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned...
2016: Journal of Nutritional Medicine and Diet Care
https://www.readbyqxmd.com/read/27730005/scutellaria-baicalensis-the-golden-herb-from-the-garden-of-chinese-medicinal-plants
#16
Qing Zhao, Xiao-Ya Chen, Cathie Martin
Scutellaria baicalensis Georgi, or Chinese skullcap, has been widely used as a medicinal plant in China for thousands of years, where the preparation from its roots is called Huang-Qin. It has been applied in the treatment of diarrhea, dysentery, hypertension, hemorrhaging, insomnia, inflammation and respiratory infections. Flavones such as baicalin, wogonoside and their aglycones baicalein wogonin are the major bioactive compounds extracted from the root of S. baicalensis. These flavones have been reported to have various pharmacological functions, including anti-cancer, hepatoprotection, antibacterial and antiviral, antioxidant, anticonvulsant and neuroprotective effects...
2016: Science Bulletin
https://www.readbyqxmd.com/read/27537870/rapid-isolation-and-determination-of-flavones-in-biological-samples-using-zinc-complexation-coupled-with-high-performance-liquid-chromatography
#17
Chenghe Sun, Hecheng Wang, Yingping Wang, Shengyuan Xiao
Chlorophyll-type contaminants are commonly encountered in the isolation and determination of flavones of plant aerial plant parts. Heme is also a difficult background substance in whole blood analysis. Both chlorophyll and heme are porphyrin type compounds. In this study, a rapid method for isolating flavones with 5-hydroxyl or ortho-hydroxyl groups from biological samples was developed based on the different solubilities of porphyrin-metal and flavone-metal complexes. It is important that other background substances, e...
August 16, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27323609/-analysis-of-medication-laws-for-chinese-medicine-treating-hypertension-patients-with-yin-defi-ciency-yang-hyperactivity-syndrome-based-on-literatures
#18
REVIEW
Ning Ma, Ya-zhu Hou, Xian-liang Wang, Jing-yuan Mao
OBJECTIVE: To analyze medication laws of Chinese medicine (CM) treatment in hypertension patients with yin deficiency yang hyperactivity syndrome. METHODS: China National Knowledge Infrastructure (CNKI, Jan. 1979-Dec 2014), Chinese Scientific Journals Database (VIP, Jan 1989-Dec2014), Chinese Biomedical Literature Database (CBM, Jan.1978-Dec.2014), Wanfang Database (Jan 1990-Dec 2014) were retrieved by using "hypertension", "CM", "Chinese herbs", "syndrome" as keywords...
April 2016: Chinese Journal of Integrated Traditional and Western Medicine
https://www.readbyqxmd.com/read/27314314/inhibition-of-advanced-glycation-end-product-formation-and-antioxidant-activity-by-extracts-and-polyphenols-from-scutellaria-alpina-l-and-s-altissima-l
#19
Izabela Grzegorczyk-Karolak, Krzysztof Gołąb, Jakub Gburek, Halina Wysokińska, Adam Matkowski
Methanolic extracts from the aerial parts and roots of two Scutellaria species, S. alpina and S. altissima, and five polyphenols from these plants demonstrated a significant ability to inhibit the formation of advanced glycation end-products (AGE) in vitro. S. alpina, which is richer in polyphenolic compounds, had strong antiglycation properties. These extracts demonstrated also high activity in the FRAP (ferric-reducing antioxidant power), antiradical (DPPH) and lipid peroxidation inhibition assays. Among the pure compounds, baicalin was the strongest glycation inhibitor (90...
June 14, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27144042/acute-hepatitis-after-ingestion-of-a-preparation-of-chinese-skullcap-and-black-catechu-for-joint-pain
#20
Charilaos Papafragkakis, Mel A Ona, Madhavi Reddy, Sury Anand
Many herbal preparations are routinely used and have been occasionally associated with a wide range of side effects, from mild to severe. Chinese skullcap and black catechu are herbal medications commonly used for their hepatoprotective and other properties. We report a case of acute toxic hepatitis associated with ingestion of Chinese skullcap and black catechu in one preparation for the alleviation of joint pain.
2016: Case Reports in Hepatology
keyword
keyword
65473
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"