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https://www.readbyqxmd.com/read/29679848/a-deep-boltzmann-machine-driven-level-set-method-for-heart-motion-tracking-using-cine-mri-images
#1
Jian Wu, Thomas R Mazur, Su Ruan, Chunfeng Lian, Nalini Daniel, Hilary Lashmett, Laura Ochoa, Imran Zoberi, Mark A Anastasio, H Michael Gach, Sasa Mutic, Maria Thomas, Hua Li
Heart motion tracking for radiation therapy treatment planning can result in effective motion management strategies to minimize radiation-induced cardiotoxicity. However, automatic heart motion tracking is challenging due to factors that include the complex spatial relationship between the heart and its neighboring structures, dynamic changes in heart shape, and limited image contrast, resolution, and volume coverage. In this study, we developed and evaluated a deep generative shape model-driven level set method to address these challenges...
April 6, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29678758/identification-of-memory-reactivation-during-sleep-by-eeg-classification
#2
Suliman Belal, James Cousins, Wael El-Deredy, Laura Parkes, Jules Schneider, Hikaru Tsujimura, Alexia Zoumpoulaki, Marta Perapoch, Lorena Santamaria Covariabus, Penelope Lewis
Memory reactivation during sleep is critical for consolidation, but also extremely difficult to measure as it is subtle, distributed and temporally unpredictable. This article reports a novel method for detecting such reactivation in standard sleep recordings. During learning, participants produced a complex sequence of finger presses, with each finger cued by a distinct audio-visual stimulus. Auditory cues were then re-played during subsequent sleep to trigger neural reactivation through a method known as targeted memory reactivation (TMR)...
April 17, 2018: NeuroImage
https://www.readbyqxmd.com/read/29678137/supporting-teams-to-optimize-function-and-independence-in-veterans-a-multi-study-program-and-mixed-methods-protocol
#3
Virginia Wang, Kelli Allen, Courtney H Van Houtven, Cynthia Coffman, Nina Sperber, Elizabeth P Mahanna, Cathleen Colón-Emeric, Helen Hoenig, George L Jackson, Teresa M Damush, Erika Price, Susan N Hastings
BACKGROUND: Successful implementation of new clinical programs depends on effectively establishing, reorganizing, or enhancing team structures and processes to coordinate the work of individuals who are interdependent in their tasks, manage relationships, and share responsibility for outcomes. However, a one-size-fits-all approach is rarely effective. In partnership with VA national clinical leaders and local clinical champions, the Optimizing Function and Independence VA Quality Enhancement Research Initiative program (Function QUERI) will evaluate efforts to implement team-based clinical programs for Veterans at risk for functional decline and disability...
April 20, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29676512/occupational-functional-plasticity-revealed-by-brain-entropy-a-resting-state-fmri-study-of-seafarers
#4
Nizhuan Wang, Huijun Wu, Min Xu, Yang Yang, Chunqi Chang, Weiming Zeng, Hongjie Yan
Recently, functional magnetic resonance imaging (fMRI) has been increasingly used to assess brain function. Brain entropy is an effective model for evaluating the alteration of brain complexity. Specifically, the sample entropy (SampEn) provides a feasible solution for revealing the brain's complexity. Occupation is one key factor affecting the brain's activity, but the neuropsychological mechanisms are still unclear. Thus, in this article, based on fMRI and a brain entropy model, we explored the functional complexity changes engendered by occupation factors, taking the seafarer as an example...
April 20, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29675961/a-path-to-the-powerhouse-systems-to-structure-approaches-for-studying-mitochondrial-proteins
#5
David J Pagliarini
The young investigator award from the Protein Society was a special honor for me because, at its essence, the goal of my laboratory is to define what obscure proteins do. Years ago, I stumbled into mitochondria as a venue for this work, and these organelles continue to define the biological theme of my laboratory. Our approaches are fairly broad, reflecting my own somewhat unorthodox training among diverse scientific fields spanning organic synthesis, chemical biology, mechanistic biochemistry, signal transduction, and systems biology...
April 20, 2018: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29675669/can-we-draw-general-conclusions-from-interval-training-studies
#6
Ricardo Borges Viana, Claudio Andre Barbosa de Lira, João Pedro Araújo Naves, Victor Silveira Coswig, Fabrício Boscolo Del Vecchio, Rodrigo Ramirez-Campillo, Carlos Alexandre Vieira, Paulo Gentil
Interval training (IT) has been used for many decades with the purpose of increasing performance and promoting health benefits while demanding a relatively small amount of time. IT can be defined as intermittent periods of intense exercise separated by periods of recovery and has been divided into high-intensity interval training (HIIT), sprint interval training (SIT), and repeated sprint training (RST). IT use has resulted in the publication of many studies and many of them with conflicting results and positions...
April 19, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29674791/research-design-the-methodology-for-interdisciplinary-research-framework
#7
Hilde Tobi, Jarl K Kampen
Many of today's global scientific challenges require the joint involvement of researchers from different disciplinary backgrounds (social sciences, environmental sciences, climatology, medicine, etc.). Such interdisciplinary research teams face many challenges resulting from differences in training and scientific culture. Interdisciplinary education programs are required to train truly interdisciplinary scientists with respect to the critical factor skills and competences. For that purpose this paper presents the Methodology for Interdisciplinary Research (MIR) framework...
2018: Quality & Quantity
https://www.readbyqxmd.com/read/29674110/resident-specific-morbidity-reduced-following-acs-nsqip-data-driven-quality-program
#8
Florence E Turrentine, John B Hanks, Megan C Tracci, R Scott Jones, Bruce D Schirmer, Philip W Smith
BACKGROUND: The Accreditation Council for Graduate Medical Education Milestone Project for general surgery provided a more robust method for developing and tracking residents' competence. This framework enhanced systematic and progressive development of residents' competencies in surgical quality improvement. STUDY DESIGN: A 22-month interactive, educational program based on resident-specific surgical outcomes data culminated in a quality improvement project for postgraduate year 4 surgery residents...
April 16, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29673570/pregnancy-and-parental-leave-among-obstetrics-and-gynecology-residents-results-of-a-nationwide-survey-of-program-directors
#9
Eduardo Hariton, Benjamin Matthews, Abigail Burns, Chitra Akileswaran, Lori R Berkowitz
INTRODUCTION: The health and economic benefits of paid parental leave have been well documented. In 2016, the American College of Obstetrics and Gynecology (ACOG) released a policy statement on recommended parental leave for trainees, yet, data on adoption of said guidelines is nonexistent and published data on parental leave policies in Ob-Gyn is outdated. The objective of our study is to understand existing parental leave policies in Ob-Gyn training programs and to evaluate program director opinions on these policies and on parenting in residency...
April 16, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29673244/changes-in-body-composition-blood-lipid-profile-and-growth-factor-hormone-in-a-patient-with-prader-willi-syndrome-during-24-weeks-of-complex-exercise-a-single-case-study
#10
Hee Joung Joung, In Soo Lim
PURPOSE: Prader-Willi syndrome (PWS) is a genetic disorder characterized by excessive appetite with progressive obesity and growth hormone (GH) deficiency. Excessive eating causes progressive obesity with increased risk of morbidities and mortality. Although GH treatment has beneficial effects on patients with PWS, adverse events have occurred during GH treatment. Exercise potentially has a positive effect on obesity management. The purpose of this research was to examine the effects of 24-week complex exercise program on changes in body composition, blood lipid profiles, and growth factor hormone levels in a patient with PWS...
March 30, 2018: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29673156/feature-extraction-for-track-section-status-classification-based-on-ugw-signals
#11
Lei Yuan, Yuan Yang, Álvaro Hernández, Lin Shi
Track status classification is essential for the stability and safety of railway operations nowadays, when railway networks are becoming more and more complex and broad. In this situation, monitoring systems are already a key element in applications dedicated to evaluating the status of a certain track section, often determining whether it is free or occupied by a train. Different technologies have already been involved in the design of monitoring systems, including ultrasonic guided waves (UGW). This work proposes the use of the UGW signals captured by a track monitoring system to extract the features that are relevant for determining the corresponding track section status...
April 17, 2018: Sensors
https://www.readbyqxmd.com/read/29671385/artificial-neural-network-modeling-for-organic-and-total-nitrogen-removal-of-aerobic-granulation-under-steady-state-condition
#12
H Gong, R Pishgar, J H Tay
Aerobic granulation is a recent technology with high level of complexity and sensitivity to environmental and operational conditions. Artificial neural networks (ANN), computational tools capable of describing complex nonlinear systems, are the best fit to simulate aerobic granular bioreactors. In this study, two feedforward backpropagation ANN models were developed to predict chemical oxygen demand (COD) (Model I) and total nitrogen (TN) removal efficiencies (Model II) of aerobic granulation technology under steady-state condition...
April 19, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29670206/heterogeneity-analysis-and-diagnosis-of-complex-diseases-based-on-deep-learning-method
#13
Xiong Li, Liyue Liu, Juan Zhou, Che Wang
Understanding genetic mechanism of complex diseases is a serious challenge. Existing methods often neglect the heterogeneity phenomenon of complex diseases, resulting in lack of power or low reproducibility. Addressing heterogeneity when detecting epistatic single nucleotide polymorphisms (SNPs) can enhance the power of association studies and improve prediction performance of complex diseases diagnosis. In this study, we propose a three-stage framework including epistasis detection, clustering and prediction to address both epistasis and heterogeneity of complex diseases based on deep learning method...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29669711/an-exercise-intervention-to-unravel-the-mechanisms-underlying-insulin-resistance-in-a-cohort-of-black-south-african-women-protocol-for-a-randomized-controlled-trial-and-baseline-characteristics-of-participants
#14
Julia H Goedecke, Amy E Mendham, Louise Clamp, Pamela A Nono Nankam, Melony C Fortuin-de Smidt, Lindokuhle Phiri, Lisa K Micklesfield, Dheshnie Keswell, Nicholas J Woudberg, Sandrine Lecour, Ali Alhamud, Mamadou Kaba, Faith M Lutomia, Paul J van Jaarsveld, Anniza de Villiers, Steven E Kahn, Elin Chorell, Jon Hauksson, Tommy Olsson
BACKGROUND: The pathogenesis of type 2 diabetes (T2D) in black African women is complex and differs from that in their white counterparts. However, earlier studies have been cross-sectional and provide little insight into the causal pathways. Exercise training is consistently used as a model to examine the mechanisms underlying insulin resistance and risk for T2D. OBJECTIVE: The objective of the study was to examine the mechanisms underlying the changes in insulin sensitivity and secretion in response to a 12-week exercise intervention in obese black South African (SA) women...
April 18, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29669709/implementing-an-open-source-electronic-health-record-system-in-kenyan-health-care-facilities-case-study
#15
Naomi Muinga, Steve Magare, Jonathan Monda, Onesmus Kamau, Stuart Houston, Hamish Fraser, John Powell, Mike English, Chris Paton
BACKGROUND: The Kenyan government, working with international partners and local organizations, has developed an eHealth strategy, specified standards, and guidelines for electronic health record adoption in public hospitals and implemented two major health information technology projects: District Health Information Software Version 2, for collating national health care indicators and a rollout of the KenyaEMR and International Quality Care Health Management Information Systems, for managing 600 HIV clinics across the country...
April 18, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29668273/filling-the-gap-in-extended-metal-atom-chains-ferromagnetic-interactions-in-a-tetrairon-ii-string-supported-by-oligo-%C3%AE-pyridylamido-ligands
#16
Alessio Nicolini, Rita Galavotti, Anne-Laure Barra, Marco Borsari, Matteo Caleffi, Guangpu Luo, Ghenadie Novitchi, Kyungwha Park, Antonio Ranieri, Luca Rigamonti, Fabrizio Roncaglia, Cyrille Train, Andrea Cornia
The stringlike complex [Fe4 (tpda)3 Cl2 ] (2; H2 tpda = N2 , N6 -bis(pyridin-2-yl)pyridine-2,6-diamine) was obtained as the first homometallic extended metal atom chain based on iron(II) and oligo-α-pyridylamido ligands. The synthesis was performed under strictly anaerobic and anhydrous conditions using dimesityliron, [Fe2 (Mes)4 ] (1; HMes = mesitylene), as both an iron source and a deprotonating agent for H2 tpda. The four lined-up iron(II) ions in the structure of 2 (Fe···Fe = 2.94-2.99 Å, Fe···Fe···Fe = 171...
April 18, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29664159/reading-aids-for-adults-with-low-vision
#17
REVIEW
Gianni Virgili, Ruthy Acosta, Sharon A Bentley, Giovanni Giacomelli, Claire Allcock, Jennifer R Evans
BACKGROUND: The purpose of low-vision rehabilitation is to allow people to resume or to continue to perform daily living tasks, with reading being one of the most important. This is achieved by providing appropriate optical devices and special training in the use of residual-vision and low-vision aids, which range from simple optical magnifiers to high-magnification video magnifiers. OBJECTIVES: To assess the effects of different visual reading aids for adults with low vision...
April 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29663574/gesture-helps-learners-learn-but-not-merely-by-guiding-their-visual-attention
#18
Elizabeth Wakefield, Miriam A Novack, Eliza L Congdon, Steven Franconeri, Susan Goldin-Meadow
Teaching a new concept through gestures-hand movements that accompany speech-facilitates learning above-and-beyond instruction through speech alone (e.g., Singer & Goldin-Meadow, ). However, the mechanisms underlying this phenomenon are still under investigation. Here, we use eye tracking to explore one often proposed mechanism-gesture's ability to direct visual attention. Behaviorally, we replicate previous findings: Children perform significantly better on a posttest after learning through Speech+Gesture instruction than through Speech Alone instruction...
April 16, 2018: Developmental Science
https://www.readbyqxmd.com/read/29663366/a-genomic-copy-number-signature-predicts-radiation-exposure-in-post-chernobyl-breast-cancer
#19
Christina M Wilke, Herbert Braselmann, Julia Hess, Sergiy V Klymenko, Vadim V Chumak, Liubov M Zakhartseva, Elena V Bakhanova, Axel K Walch, Martin Selmansberger, Daniel Samaga, Peter Weber, Ludmila Schneider, Falko Fend, Hans C Bösmüller, Horst Zitzelsberger, Kristian Unger
Breast cancer is the second leading cause of cancer death among women worldwide and besides life-style, age and genetic risk factors, exposure to ionising radiation is known to increase the risk for breast cancer. Further, DNA copy number alterations (CNAs), which can result from radiation-induced double-strand breaks, are frequently occurring in breast cancer cells. We set out to identify a signature of CNAs discriminating breast cancers from radiation-exposed and non-exposed female patients. We analysed resected breast cancer tissues from 68 exposed female Chernobyl clean-up workers and evacuees and 68 matched non-exposed control patients for CNAs by array comparative genomic hybridisation analysis (aCGH)...
April 16, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29663090/human-activity-recognition-from-body-sensor-data-using-deep-learning
#20
Mohammad Mehedi Hassan, Shamsul Huda, Md Zia Uddin, Ahmad Almogren, Majed Alrubaian
In recent years, human activity recognition from body sensor data or wearable sensor data has become a considerable research attention from academia and health industry. This research can be useful for various e-health applications such as monitoring elderly and physical impaired people at Smart home to improve their rehabilitation processes. However, it is not easy to accurately and automatically recognize physical human activity through wearable sensors due to the complexity and variety of body activities...
April 16, 2018: Journal of Medical Systems
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