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https://www.readbyqxmd.com/read/28550423/tactile-feedback-is-an-effective-instrument-for-the-training-of-grasping-with-a-prosthesis-at-low-and-medium-force-levels
#1
Alessandro Marco De Nunzio, Strahinja Dosen, Sabrina Lemling, Marko Markovic, Meike Annika Schweisfurth, Nan Ge, Bernhard Graimann, Deborah Falla, Dario Farina
Grasping is a complex task routinely performed in an anticipatory (feedforward) manner, where sensory feedback is responsible for learning and updating the internal model of grasp dynamics. This study aims at evaluating whether providing a proportional tactile force feedback during the myoelectric control of a prosthesis facilitates learning a stable internal model of the prosthesis force control. Ten able-bodied subjects controlled a sensorized myoelectric prosthesis performing four blocks of consecutive grasps at three levels of target force (30, 50, and 70%), repeatedly closing the fully opened hand...
May 26, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28550244/apoe-%C3%AE%C2%B54-modulation-of-training-outcomes-in-several-cognitive-domains-in-a-sample-of-cognitively-intact-older-adults
#2
Ramón López-Higes, Inmaculada C Rodríguez-Rojo, José M Prados, Pedro Montejo, David Del-Río, María Luisa Delgado-Losada, Mercedes Montenegro, David López-Sanz, Ana Barabash
BACKGROUND: Most research points to the ɛ4 allele of the apolipoprotein E (APOE) gene as the most recognizable genetic risk factor associated with Alzheimer's disease pathogenesis. It has been also suggested that the APOEɛ4 allele has a negative influence on cognitive functioning, which begins long before cognitive impairment becomes manifest. However, still, little is known about the APOEɛ4 interaction with cognitive intervention programs. OBJECTIVE: The main goal of this study was to explore whether there was a differential APOE genotype modulation effect after cognitive training in different domains, such as language comprehension, executive functions, and memory...
May 25, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28549765/improving-patient-centered-transitional-care-after-complex-abdominal-surgery
#3
Alexandra W Acher, Stephanie A Campbell-Flohr, Maria Brenny-Fitzpatrick, Kristine M Leahy-Gross, Sara Fernandes-Taylor, Alexander V Fisher, Suresh Agarwal, Amy J Kind, Caprice C Greenberg, Pascale Carayon, Sharon M Weber
BACKGROUND: Poor-quality transitions of care from hospital to home contribute to high rates of readmission after complex abdominal surgery. The Coordinated Transitional Care (C-TraC) program improved readmission rates in medical patients, but evidence-based surgical transitional care protocols are lacking. This pilot study evaluated the feasibility and preliminary effectiveness of an adapted surgical C-TraC protocol. STUDY DESIGN: The intervention includes in-person enrollment of patients...
May 18, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28549752/inter-rater-variability-in-motor-function-assessment-in-parkinson-s-disease-between-experts-in-movement-disorders-and-nurses-specialising-in-pd-management
#4
T de Deus Fonticoba, D Santos García, M Macías Arribí
INTRODUCTION AND OBJECTIVE: In clinical practice, assessing patients with Parkinson's disease (PD) is a complex, time-consuming task. Our purpose is to provide a rigorous and objective evaluation of how motor function in PD patients is assessed by neurologists specialising in movement disorders, on the one hand, and by nurses specialising in PD management, on the other. METHODS: We conducted an observational, cross-sectional, single-centre study of 50 patients with PD (52% men; mean age: 64...
May 23, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28549743/intensive-care-nursing-students-perceptions-of-simulation-for-learning-confirming-communication-skills-a-descriptive-qualitative-study
#5
Marte-Marie Wallander Karlsen, Anita Kristin Gabrielsen, Anne Lise Falch, Dag-Gunnar Stubberud
AIM: The aim of this study was to explore intensive care nursing students experiences with confirming communication skills training in a simulation-based environment. RESEARCH METHODOLOGY: The study has a qualitative, exploratory and descriptive design. The participants were students in a post-graduate program in intensive care nursing, that had attended a one day confirming communication course. Three focus group interviews lasting between 60 and 80min were conducted with 14 participants...
May 23, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28549410/large-scale-tissue-histopathology-image-classification-segmentation-and-visualization-via-deep-convolutional-activation-features
#6
Yan Xu, Zhipeng Jia, Liang-Bo Wang, Yuqing Ai, Fang Zhang, Maode Lai, Eric I-Chao Chang
BACKGROUND: Histopathology image analysis is a gold standard for cancer recognition and diagnosis. Automatic analysis of histopathology images can help pathologists diagnose tumor and cancer subtypes, alleviating the workload of pathologists. There are two basic types of tasks in digital histopathology image analysis: image classification and image segmentation. Typical problems with histopathology images that hamper automatic analysis include complex clinical representations, limited quantities of training images in a dataset, and the extremely large size of singular images (usually up to gigapixels)...
May 26, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28548998/zygomaticomaxillary-complex-fractures-diagnosis-and-treatment
#7
Nicholas Peretti, Stephen MacLeod
PURPOSE OF REVIEW: To provide an overview of zygomaticomaxillary complex (ZMC) fractures and their treatment. Aspects of anatomy, diagnosis, and treatment objectives of these common fractures will be reviewed including recent literature. RECENT FINDINGS: Advances in technology such as guided surgery have allowed for better outcomes and a reduction in surgeon variability with regard to postoperative results. The use of titanium and bioresorbable mini screws and plates have expanded the ability to achieve stable and predictable results...
May 25, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28548536/inductive-supervised-quantum-learning
#8
Alex Monràs, Gael Sentís, Peter Wittek
In supervised learning, an inductive learning algorithm extracts general rules from observed training instances, then the rules are applied to test instances. We show that this splitting of training and application arises naturally, in the classical setting, from a simple independence requirement with a physical interpretation of being nonsignaling. Thus, two seemingly different definitions of inductive learning happen to coincide. This follows from the properties of classical information that break down in the quantum setup...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28546534/classification-of-paediatric-inflammatory-bowel-disease-using-machine-learning
#9
E Mossotto, J J Ashton, T Coelho, R M Beattie, B D MacArthur, S Ennis
Paediatric inflammatory bowel disease (PIBD), comprising Crohn's disease (CD), ulcerative colitis (UC) and inflammatory bowel disease unclassified (IBDU) is a complex and multifactorial condition with increasing incidence. An accurate diagnosis of PIBD is necessary for a prompt and effective treatment. This study utilises machine learning (ML) to classify disease using endoscopic and histological data for 287 children diagnosed with PIBD. Data were used to develop, train, test and validate a ML model to classify disease subtype...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546312/prefrontal-dopamine-d1-and-d2-receptors-regulate-dissociable-aspects-of-decision-making-via-distinct-ventral-striatal-and-amygdalar-circuits
#10
Nicole L Jenni, Joshua D Larkin, Stan B Floresco
Mesocortical dopamine (DA) regulates a variety of cognitive functions via actions on D1 and/or D2 receptors. For example, risk/reward decision making is differentially modulated by these two receptors within the prefrontal cortex (PFC), with D2 receptors enabling flexible decision making and D1 receptors promoting persistence in choice biases. Yet, it is unclear how DA mediates opposing patterns of behavior by acting on different receptors within the same terminal region. We explored the possibility that DA may act on separate networks of PFC neurons that are modulated by D1 or D2 receptors and in turn interface with divergent downstream structures, such as the basolateral amygdala (BLA) or nucleus accumbens (NAc)...
May 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28545425/mental-health-training-programmes-for-non-mental-health-trained-professionals-coming-into-contact-with-people-with-mental-ill-health-a-systematic-review-of-effectiveness
#11
Alison Booth, Arabella Scantlebury, Adwoa Hughes-Morley, Natasha Mitchell, Kath Wright, William Scott, Catriona McDaid
BACKGROUND: The police and others in occupations where they come into close contact with people experiencing/with mental ill health, often have to manage difficult and complex situations. Training is needed to equip them to recognise and assist when someone has a mental health issue or learning/intellectual disability. We undertook a systematic review of the effectiveness of training programmes aimed at increasing knowledge, changing behaviour and/or attitudes of the trainees with regard to mental ill health, mental vulnerability, and learning disabilities...
May 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28543088/3d-quantitative-structure-activity-relationship-and-docking-studies-of-coumarin-derivatives-as-tissue-kallikrein-7-inhibitors
#12
Xin Zheng, Mengxi He, Xiao Tan, Jun Zheng, Fangyu Wang, Sen Liu
OBJECTIVES: Kallikrein 7 (KLK7) is a secreted serine protease that plays important roles in skin desquamation and tumour progression, which makes it an attracting drug target. To guide the design of KLK7 inhibitors, a series of coumarin-based inhibitors were used to perform 3D-quantitative structure-activity relationship analysis. METHODS: 3D conformations of 37 inhibitors were generated and used to construct CoMFA and CoMSIA models. Then a complex model between the inhibitors and KLK7 was built with molecular docking...
May 23, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28542581/spontaneous-bimanual-independence-during-parallel-tapping-and-sawing
#13
Sandra Dorothee Starke, Chris Baber
The performance of complex polyrhythms-rhythms where the left and right hand move at different rates-is usually the province of highly trained individuals. However, studies in which hand movement is guided haptically show that even novices can perform polyrhythms with no or only brief training. In this study, we investigated whether novices are able to tap with one hand by matching different rates of a metronome while sawing with the other hand. This experiment was based on the assumption that saw movement is controlled consistently at a predictable rate without the need for paying primary attention to it...
2017: PloS One
https://www.readbyqxmd.com/read/28541193/analysis-of-energy-based-metrics-for-laparoscopic-skills-assessment
#14
Behnaz Poursartip, Marie-Eve LeBel, Rajni Patel, Michael Naish, Ana Luisa Trejos
OBJECTIVE: The complexity of Minimally Invasive Surgery (MIS) requires that trainees practice MIS skills in numerous training sessions. The goal of these training sessions is to learn how to move the instruments smoothly without damaging the surrounding tissue and achieving operative tasks with accuracy. In order to enhance the efficiency of these training sessions, the proficiency of the trainees should be assessed using an objective assessment method. Several performance metrics have been proposed and analyzed for MIS tasks...
May 19, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28540771/identifying-therapeutic-targets-for-alzheimer-s-disease-with-big-data
#15
Nilüfer Ertekin-Taner
Nilüfer Ertekin-Taner is a Professor of Neuroscience and Neurology at the Mayo Clinic, Jacksonville, FL, USA. A neurogeneticist and board-certified behavioral neurologist, she received her medical degree from Hacettepe University Medical School in Ankara, Turkey and her doctorate degree in Molecular Neuroscience from Mayo Graduate School. She completed her residency training in the Department of Neurology at Mayo Clinic in Rochester (MN, USA) and fellowship in Behavioral Neurology at Mayo Clinic in Jacksonville...
April 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28539192/shared-decision-making-and-the-promise-of-a-respectful-and-equitable-healthcare-system-in-peru
#16
Germán Málaga, Zoila O Romero, Ariana S Málaga, Sofia Cuba-Fuentes
Peru has achieved sustained development in the last two decades. However, despite this achievement, it has not been matched with improvements in the quality of education and health; investment in both sectors is among the lowest in the region. This situation perpetuates huge gaps in infrastructure and also conditions a poor literacy level of the population specifically in health. Currently, there is a fragmented model of patient care, in which the systems are exclusive of each other. They do not cooperate or communicate with each other; and if there is no vertical communication within the system, preventing referral of patients directly from the basic level to the complex level of care when needed...
May 20, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28538294/effects-of-different-combinations-of-strength-power-and-plyometric-training-on-the-physical-performance-of-elite-young-soccer-players
#17
Ronaldo Kobal, Irineu Loturco, Renato Barroso, Saulo Gil, Rogério Cuniyochi, Carlos Ugrinowitsch, Hamilton Roschel, Valmor Tricoli
Kobal, R, Loturco, I, Barroso, R, Gil, S, Cuniyochi, R, Ugrinowitsch, C, Roschel, H, and Tricoli, V. Effects of different combinations of strength, power, and plyometric training on the physical performance of elite young soccer players. J Strength Cond Res 31(6): 1468-1476, 2017-The combination of strength (ST) and plyometric training (PT) has been shown to be effective for improving sport-specific performance. However, there is no consensus about the most effective way to combine these methods in the same training session to produce greater improvements in neuromuscular performance of soccer players...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28537848/influence-of-endurance-training-on-skeletal-muscle-mitophagy-regulatory-proteins-in-type-2-diabetic-men
#18
Christian Brinkmann, Axel Przyklenk, Alexander Metten, Thorsten Schiffer, Wilhelm Bloch, Klara Brixius, Sebastian Gehlert
BACKGROUND: Mitophagy is a form of autophagy for the elimination of mitochondria. Mitochondrial content and function are reduced in the skeletal muscle of patients with type 2 diabetes mellitus (T2DM). Physical training has been shown to restore mitochondrial capacity in T2DM patients, but the role of mitophagy has not been examined in this context. This study analyzes the impact of a 3-month endurance training on important skeletal muscle mitophagy regulatory proteins and oxidative phosphorylation (OXPHOS) complexes in T2DM patients...
May 24, 2017: Endocrine Research
https://www.readbyqxmd.com/read/28537209/development-of-the-icd-10-simplified-version-and-field-test
#19
Wansa Paoin, Maliwan Yuenyongsuwan, Yukiko Yokobori, Hiroyoshi Endo, Sukil Kim
BACKGROUND: The International Statistical Classification of Diseases and Related Health Problems, 10th Revision (ICD-10) has been used in various Asia-Pacific countries for more than 20 years. Although ICD-10 is a powerful tool, clinical coding processes are complex; therefore, many developing countries have not been able to implement ICD-10-based health statistics (WHO-FIC APN, 2007). OBJECTIVE: This study aimed to simplify ICD-10 clinical coding processes, to modify index terms to facilitate computer searching and to provide a simplified version of ICD-10 for use in developing countries...
January 1, 2017: HIM Journal
https://www.readbyqxmd.com/read/28534791/a-self-paced-regularization-framework-for-multilabel-learning
#20
Changsheng Li, Fan Wei, Junchi Yan, Xiaoyu Zhang, Qingshan Liu, Hongyuan Zha
In this brief, we propose a novel multilabel learning framework, called multilabel self-paced learning, in an attempt to incorporate the SPL scheme into the regime of multilabel learning. Specifically, we first propose a new multilabel learning formulation by introducing a self-paced function as a regularizer, so as to simultaneously prioritize label learning tasks and instances in each iteration. Considering that different multilabel learning scenarios often need different self-paced schemes during learning, we thus provide a general way to find the desired self-paced functions...
May 16, 2017: IEEE Transactions on Neural Networks and Learning Systems
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