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https://www.readbyqxmd.com/read/28528447/a-single-bout-of-endurance-exercise-modulates-eeg-microstates-temporal-features
#1
Jérôme N Spring, Miralena I Tomescu, Jérôme Barral
Electrical neuroimaging is a promising method to explore the spontaneous brain function after physical exercise. The present study aims to investigate the effect of acute physical exercise on the temporal dynamic of the resting brain activity captured by the four conventional map topographies (microstates) described in the literature, and to associate these brain changes with the post-exercise neuromuscular function. Twenty endurance-trained subjects performed a 30-min biking task at 60% of their maximal aerobic power followed by a 10 km all-out time trial...
May 20, 2017: Brain Topography
https://www.readbyqxmd.com/read/28527225/clinical-feasibility-of-gait-training-with-a%C3%A2-robotic-exoskeleton-wpal-in-an-individual-with-both-incomplete-cervical-and-complete-thoracic-spinal-cord-injury-a%C3%A2-case-study
#2
Shigeo Tanabe, Soichiro Koyama, Eiichi Saitoh, Satoshi Hirano, Kanan Yatsuya, Tetsuya Tsunoda, Masaki Katoh, Takeshi Gotoh, Ayako Furumoto
BACKGROUND: Patients with tetraplegia can achieve independent gait with lateral-type powered exoskeletons; it is unclear whether medial-type powered exoskeletons allow for this. OBJECTIVE: To investigate gait training with a medial-type powered exoskeleton wearable power-assist locomotor (WPAL) in an individual with incomplete cervical (C5) and complete thoracic (T12) spinal cord injury (SCI). METHODS: The 60-session program was investigated retrospectively using medical records...
May 19, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28527066/community-pharmacies-as-epidemiological-sentinels-of-headache-first-experience-in-italy
#3
Paola Brusa, Marco Parente, Gianni Allais, Sara Rolando, Giuseppe Costa, Roberto Gnavi, Teresa Spadea, Mario Giaccone, Andrea Mandelli, Massimo Mana, Francesca Baratta, Chiara Benedetto, Gennaro Bussone
Migraine is a disabling neurovascular syndrome which affects 12-15% of the global population and it represents the third cause in years lived with disability in both males and females aged 15-49 years. Among migraineurs, the symptomatic drug abuse may be a risk factor in the development of medication overuse headache (MOH). Detecting cases of MOH is not straightforward; community pharmacists may, therefore, be in a strategic position to identify individuals who self-medicate, particularly with respect to prevent the development of MOH...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526512/privacy-trainee-rights-and-accountability-in-radiology-education
#4
REVIEW
Cory M Pfeifer
RATIONALE AND OBJECTIVES: Academic radiologists commonly hold multiple simultaneous roles within the landscape of physician training. This paper analyzes theoretical scenarios describing relationships between medical students, residents, and physician educators in radiology. MATERIALS AND METHODS: The scenarios presented involve medical student supervision, radiology resident recruitment, and resident termination with respect to relevant ethical, regulatory, and legal considerations...
March 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28525311/telerehabilitation-of-patients-with-injuries-of-the-lower-extremities
#5
Andriy I Tsvyakh, Andriy J Hospodarskyy
INTRODUCTION: Timely access to orthopedic rehabilitation is an important problem for the Ukrainian healthcare system. The international orthopedic community aims to achieve the best possible outcome for patient care by modifying rehabilitation methods and using telemedicine technology. The theme of this article is to discuss the integration of telemedicine technology in the rehabilitation of patients with injuries of the lower extremities. MATERIALS AND METHODS: Consecutive patients were recruited over a 2-year period...
May 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28523517/body-size-of-male-youth-soccer-players-1978-2015
#6
REVIEW
Robert M Malina, António J Figueiredo, Manuel J Coelho-E-Silva
BACKGROUND: Studies of the body size and proportions of athletes have a long history. Comparisons of athletes within specific sports across time, though not extensive, indicate both positive and negative trends. OBJECTIVE: To evaluate secular variation in heights and weights of male youth soccer players reported in studies between 1978 and 2015. METHODS: Reported mean ages, heights, and weights of male soccer players 9-18 years of age were extracted from the literature and grouped into two intervals: 1978-99 and 2000-15...
May 18, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28523084/survey-of-current-practice-patterns-in-the-management-of-frontal-sinus-fractures
#7
Kevin J Choi, Bora Chang, Charles R Woodard, David B Powers, Jeffrey R Marcus, Liana Puscas
The management of frontal sinus fractures has evolved in the endoscopic era. The development of functional endoscopic sinus surgery (FESS) has been incorporated into management algorithms proposed by otolaryngologists, but the extent of its influence on plastic surgeons and oral and maxillofacial surgeons is heretofore unknown. A cross-sectional survey was performed to assess the practice pattern variations in frontal sinus fracture management across multiple surgical disciplines. A total of 298 surveys were reviewed...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28522972/recent-advances-in-the-study-of-bipolar-rod-shaped-microglia-and-their-roles-in-neurodegeneration
#8
Ngan Pan Bennett Au, Chi Him Eddie Ma
Microglia are the resident immune cells of the central nervous system (CNS) and they contribute to primary inflammatory responses following CNS injuries. The morphology of microglia is closely associated with their functional activities. Most previous research efforts have attempted to delineate the role of ramified and amoeboid microglia in the pathogenesis of neurodegenerative diseases. In addition to ramified and amoeboid microglia, bipolar/rod-shaped microglia were first described by Franz Nissl in 1899 and their presence in the brain was closely associated with the pathology of infectious diseases and sleeping disorders...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28521049/22q11-2-deletion-syndrome-is-associated-with-impaired-auditory-steady-state-gamma-response
#9
Kit Melissa Larsen, Giovanni Pellegrino, Michelle Rosgaard Birknow, Trine Nørgaard Kjær, William Frans Christiaan Baaré, Michael Didriksen, Line Olsen, Thomas Werge, Morten Mørup, Hartwig Roman Siebner
Background: The 22q11.2 deletion syndrome confers a markedly increased risk for schizophrenia. 22q11.2 deletion carriers without manifest psychotic disorder offer the possibility to identify functional abnormalities that precede clinical onset. Since schizophrenia is associated with a reduced cortical gamma response to auditory stimulation at 40 Hz, we hypothesized that the 40 Hz auditory steady-state response (ASSR) may be attenuated in nonpsychotic individuals with a 22q11.2 deletion...
May 17, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28520235/high-dimensional-neural-network-potentials-for-complex-systems
#10
Jörg Behler
Modern simulation techniques have reached a level of maturity, which allows addressing a wide range of problems in chemistry and materials science. Unfortunately, the application of first principles methods with predictive power is still limited to rather small systems, and in spite of the rapid evolution of computer hardware no fundamental change of this situation can be expected. Consequently, to reach an atomic level understanding of complex systems, the development of more efficient but equally reliable atomistic potentials has received considerable attention in recent years...
May 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28516252/chronic-eccentric-arm-cycling-improves-maximum-upper-body-strength-and-power
#11
Steven J Elmer, Dakota J Anderson, Travis R Wakeham, Matthew A Kilgas, John J Durocher, Stan L Lindstedt, Paul C LaStayo
INTRODUCTION: Eccentric leg cycling (cycle ergometry adapted to impose muscle lengthening contractions) offers an effective exercise for restoring lower-body muscular function, maintaining health, and improving performance in clinical and athletic populations. PURPOSE: We extended this model to the upper body and evaluated the effectiveness of a 7-week eccentric arm cycling (ECCarm) intervention to improve upper-body muscular function. We also explored whether ECCarm would alter arterial function...
May 17, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28515105/free-circulating-methylated-dna-in-blood-for-diagnosis-staging-prognosis-and-monitoring-of-head-and-neck-squamous-cell-carcinoma-patients-an-observational-prospective-cohort-study
#12
Andreas Schröck, Annette Leisse, Luka de Vos, Heidrun Gevensleben, Freya Dröge, Alina Franzen, Malin Wachendörfer, Friederike Schröck, Joerg Ellinger, Marcus Teschke, Timo Wilhelm-Buchstab, Jennifer Landsberg, Stefan Holdenrieder, Gunther Hartmann, John K Field, Friedrich Bootz, Glen Kristiansen, Dimo Dietrich
BACKGROUND: Circulating cell-free DNA methylation testing in blood has recently received regulatory approval for screening of colorectal cancer. Its application in other clinical settings, including staging, prognosis, prediction, and recurrence monitoring is highly promising, and of particular interest in head and neck squamous cell carcinomas (HNSCC) that represent a heterogeneous group of cancers with unsatisfactory treatment guidelines. METHODS: Short stature homeobox 2 (SHOX2) and septin 9 (SEPT9) DNA methylation in plasma from 649 prospectively enrolled patients (training study: 284 HNSCC/122 control patients; testing study: 141 HNSCC/102 control patients) was quantified before treatment and longitudinally during surveillance...
May 17, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28512438/are-neurodynamic-organizations-a-fundamental-property-of-teamwork
#13
Ronald H Stevens, Trysha L Galloway
When performing a task it is important for teams to optimize their strategies and actions to maximize value and avoid the cost of surprise. The decisions teams make sometimes have unintended consequences and they must then reorganize their thinking, roles and/or configuration into corrective structures more appropriate for the situation. In this study we ask: What are the neurodynamic properties of these reorganizations and how do they relate to the moment-by-moment, and longer, performance-outcomes of teams?...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28510504/cardiopulmonary-exercise-testing-basics-of-methodology-and-measurements
#14
Alessandro Mezzani
Cardiopulmonary exercise testing adds measurement of ventilation and volume of oxygen uptake and exhaled carbon dioxide to routine physiological and performance parameters obtainable from conventional exercise testing, furnishing an all-round vision of the systems involved in both oxygen transport from air to mitochondria and its utilization during exercise. Peculiarities of cardiopulmonary exercise testing methodology are the use of ramp protocols and calibration procedures for flow meters and gas analyzers...
May 16, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28507285/multivariate-eeg-analyses-support-high-resolution-tracking-of-feature-based-attentional-selection
#15
Johannes Jacobus Fahrenfort, Anna Grubert, Christian N L Olivers, Martin Eimer
The primary electrophysiological marker of feature-based selection is the N2pc, a lateralized posterior negativity emerging around 180-200 ms. As it relies on hemispheric differences, its ability to discriminate the locus of focal attention is severely limited. Here we demonstrate that multivariate analyses of raw EEG data provide a much more fine-grained spatial profile of feature-based target selection. When training a pattern classifier to determine target position from EEG, we were able to decode target positions on the vertical midline, which cannot be achieved using standard N2pc methodology...
May 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28507192/performance-fatigability-mechanisms-and-task-specificity
#16
Sandra K Hunter
Performance fatigability is characterized as an acute decline in motor performance caused by an exercise-induced reduction in force or power of the involved muscles. Multiple mechanisms contribute to performance fatigability and originate from neural and muscular processes, with the task demands dictating the mechanisms. This review highlights that (1) inadequate activation of the motoneuron pool can contribute to performance fatigability, and (2) the demands of the task and the physiological characteristics of the population assessed, dictate fatigability and the involved mechanisms...
May 15, 2017: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/28505991/lower-extremity-robotic-exoskeleton-training-case-studies-for-complete-spinal-cord-injury-walking
#17
Edward D Lemaire, Andrew J Smith, Andrew Herbert-Copley, Vidya Sreenivasan
BACKGROUND: Recent advances in exoskeleton technology has made lower extremity powered exoskeletons (LEPE) a viable treatment tool to restore upright walking mobility to persons with spinal cord injury (SCI). OBJECTIVE: Evaluate ARKE exoskeleton training within a rehabilitation centre environment. METHODS: Case studies are presented for two male participants, age 41 and 30, motor complete SCI at T6 (N01) and T12 (N02), respectively, as they progress from new LEPE users to independent walking...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28505227/resveratrol-enhances-exercise-induced-cellular-and-functional-adaptations-of-skeletal-muscle-in-older-men-and-women
#18
Stephen E Alway, Jean L McCrory, Kalen Kearcher, Austen Vickers, Benjamin Frear, Diana L Gilleland, Daniel E Bonner, James M Thomas, David A Donley, Mathew W Lively, Junaith S Mohamed
Older men (n = 12) and women (n = 18) 65-80 years of age completed 12 weeks of exercise and took either a placebo or resveratrol (500 mg/d) to test the hypothesis that resveratrol treatment combined with exercise would increase mitochondrial density, muscle fatigue resistance and cardiovascular function more than exercise alone. Contrary to our hypothesis, aerobic and resistance exercise coupled with resveratrol treatment did not reduce cardiovascular risk further than exercise alone. However, exercise added to resveratrol treatment improved the indices of mitochondrial density, and muscle fatigue resistance more than placebo and exercise treatments...
May 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28504971/robust-tactile-sensory-responses-in-finger-area-of-primate-motor-cortex-relevant-to-prosthetic-control
#19
Karen E Schroeder, Zachary Irwin, Autumn Bullard, David Thompson, Nicole Bentley, William Stacey, Parag Patil, Cynthia Chestek
OBJECTIVE:  Challenges in improving the performance of dexterous upper-limb brain-machine interfaces (BMIs) have prompted renewed interest in quantifying the amount and type of sensory information naturally encoded in primary motor cortex (M1). Previous single unit studies in monkeys showed M1 is responsive to tactile stimulation, as well as passive and active movement of the limbs. However, recent work in this area has focused primarily on proprioception. Here we examined instead how tactile somatosensation of the hand and fingers is represented in M1...
May 15, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28503546/computational-tool-for-fast-in-silico-evaluation-of-herg-k-channel-affinity
#20
Giulia Chemi, Sandra Gemma, Giuseppe Campiani, Simone Brogi, Stefania Butini, Margherita Brindisi
The development of a novel comprehensive approach for the prediction of hERG activity is herein presented. Software Phase has been used to derive a 3D-QSAR model, employing as alignment rule a common pharmacophore built on a subset of 22 highly active compounds (threshold Ki: 50 nM) against hERG K(+) channel. Five features comprised the pharmacophore: two aromatic rings (R1 and R2), one hydrogen-bond acceptor (A), one hydrophobic site (H), and one positive ionizable function (P). The sequential 3D-QSAR model developed with a set of 421 compounds (randomly divided in training and test set) yielded a test set (Q(2)) = 0...
2017: Frontiers in Chemistry
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