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adult asthma inhaler adherence

Ryo Atsuta, Yasuo To, Susumu Sakamoto, Isao Mukai, Akihiro Kobayashi, Arisa Kinoshita, Kazuhisa Takahashi
BACKGROUND: Maintaining high treatment adherence levels is critical for effective management of chronic diseases. The Adherence Starts with Knowledge 20 (ASK-20) questionnaire is the only linguistically validated patient-reported treatment adherence tool available in Japan. We conducted additional analyses on ASK-20 data from Japanese adults with asthma. METHODS: This was a prospective, non-interventional, single-visit, multi-centre study in Japanese adults (n = 300) with asthma receiving long-term treatment with inhaled corticosteroids (ICS) or ICS/long-acting beta-agonists...
October 3, 2016: Allergology International: Official Journal of the Japanese Society of Allergology
Lucie Blais, Fatima-Zohra Kettani, Amélie Forget, Marie-France Beauchesne, Catherine Lemière, Francine M Ducharme
PURPOSE: There are very few studies on primary adherence (i.e., first filling of a prescription) to inhaled corticosteroids (ICS) in asthma patients; two have involved children. Moreover, adherence can be overestimated when considering only secondary adherence (i.e., following the medication recommendations for a defined period) and ignoring primary adherence. We aimed thus to evaluate the real-world primary and secondary adherence to ICS and to develop an integrated primary and secondary adherence (IPSA) measure...
October 1, 2016: European Journal of Clinical Pharmacology
Jonathan M Feldman, Lynne Matte, Alejandro Interian, Paul M Lehrer, Shou-En Lu, Bari Scheckner, Dara M Steinberg, Tanya Oken, Anu Kotay, Sumita Sinha, Chang Shim
Confusion between panic and asthma symptoms can result in serious self-management errors. A cognitive behavior psychophysiological therapy (CBPT) intervention was culturally adapted for Latinos consisting of CBT for panic disorder (PD), asthma education, differentiation between panic and asthma symptoms, and heart rate variability biofeedback. An RCT compared CBPT to music and relaxation therapy (MRT), which included listening to relaxing music and paced breathing at resting respiration rates. Fifty-three Latino (primarily Puerto Rican) adults with asthma and PD were randomly assigned to CBPT or MRT for 8 weekly sessions...
September 17, 2016: Behaviour Research and Therapy
Monica Bidwal, Kajua Lor, Junhua Yu, Eric Ip
BACKGROUND: Adherence with asthma medications is less than optimal, measuring approximately 30-50%. Several factors have been shown to contribute to medication non-adherence including low-socioeconomic status, low literacy, medication cost, access to care, and language barriers. Community Health Clinic Ole has attempted to reduce medication adherence barriers associated with cost, access to care, and language by 1) allowing medications to be obtained from the clinic at a reduced cost via the 340B drug pricing program and patient assistance programs, and 2) providing one-on-one consultations from bilingual Spanish-speaking clinicians...
August 3, 2016: Research in Social & Administrative Pharmacy: RSAP
Anke Kondla, Thomas Glaab, Riccardo Pedersini, Marek Lommatzsch
BACKGROUND: The prevalence and the characteristics of poor asthma control among adults treated with combinations of inhaled corticosteroids (ICS) and long-acting beta-agonists (LABA) are not completely understood. METHODS: Data from adult patients in Germany with self-reported asthma treated with an ICS-LABA combination in the National Health and Wellness Survey (NHWS) were analysed. Patients with well-controlled and not well-controlled asthma according to the Asthma Control Test (ACT) score were compared, with respect to socio-demographic characteristics, attitudes, adherence and outcomes...
September 2016: Respiratory Medicine
Francine M Ducharme, Alexandrine J Lamontagne, Lucie Blais, Roland Grad, Kim L Lavoie, Simon L Bacon, Martha L McKinney, Eve Desplats, Pierre Ernst
Objective. We aimed to identify key enablers of physician prescription of a long-term controller in patients with persistent asthma. Methods. We conducted a mailed survey of randomly selected Quebec physicians. We sent a 102-item questionnaire, seeking reported management regarding one of 4 clinical vignettes of a poorly controlled adult or child and endorsement of enablers to prescribe long-term controllers. Results. With a 56% participation rate, 421 physicians participated. Most (86%) would prescribe a long-term controller (predominantly inhaled corticosteroids, ICS) to the patient in their clinical vignette...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Justin T Koufopoulos, Mark T Conner, Peter H Gardner, Ian Kellar
BACKGROUND: Online communities hold great potential as interventions for health, particularly for the management of chronic illness. The social support that online communities can provide has been associated with positive treatment outcomes, including medication adherence. There are few studies that have attempted to assess whether membership of an online community improves health outcomes using rigorous designs. OBJECTIVE: Our objective was to conduct a rigorous proof-of-concept randomized controlled trial of an online community intervention for improving adherence to asthma medicine...
2016: Journal of Medical Internet Research
Suzanne G Bollmeier, Theresa R Prosser
OBJECTIVE: Fluticasone furoate (FF), an inhaled corticosteroid (ICS), and vilanterol (VI), a long-acting beta2 receptor agonist (LABA), is a new combination used in an Ellipta(®) device. This article compares FF-VI to other ICS-LABA combinations available, particularly emphasizing product selection from the patient perspective. DATA SOURCES: A PubMED and EMBASE search completed in October 2015 identified trials using the MeSH terms "fluticasone", "vilanterol", and "asthma"...
2016: Patient Preference and Adherence
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No abstract text is available yet for this article.
June 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Valerie G Press, Vineet M Arora, Kristin C Trela, Richa Adhikari, Frank J Zadravecz, Chuanhong Liao, Edward Naureckas, Steven R White, David O Meltzer, Jerry A Krishnan
RATIONALE: The most effective approach to teaching respiratory inhaler technique is unknown. OBJECTIVES: To evaluate the relative effects of two different educational strategies (teach-to-goal instruction vs. brief verbal instruction) in adults hospitalized with asthma or chronic obstructive pulmonary disease. METHODS: We conducted a randomized clinical trial at two urban academic hospitals. Participants received teach-to-goal or brief instruction in the hospital and were followed for 90 days after discharge...
June 2016: Annals of the American Thoracic Society
Barbara P Yawn, Matthew A Rank, Michael D Cabana, Peter C Wollan, Young J Juhn
OBJECTIVE: To assess primary care adherence to 2007 US asthma guidelines. PATIENTS AND METHODS: Patients with persistent asthma aged 5 to 65 years from 22 primary care participating practices provided the data for this analysis of baseline information from the pragmatic randomized clinical trial the Asthma Tools Study. Using a combination of abstracted medical record data and patient-reported demographic information, we assessed the medical record documentation for elements of the 2007 US asthma guidelines...
April 2016: Mayo Clinic Proceedings
Sue J Lee, Kathleen J Pincus, Adrienne A Williams
BACKGROUND: Medication adherence can be said to begin with the patient acquiring, or picking up their prescribed medications. There has been considerable study of asthma patients' adherence beliefs once they have possessed medication; however, little is known about attitudes that facilitate or impede their acquisition of such medication. OBJECTIVES: The purpose of this study was to examine the behavioral influences, motivation, and self-efficacy that may guide a patient's decision to pick up asthma controller medications from the pharmacy for the treatment of persistent asthma...
September 2016: Research in Social & Administrative Pharmacy: RSAP
Ashley Woodcock, Nawar Diar Bakerly, John P New, J Martin Gibson, Wei Wu, Jørgen Vestbo, David Leather
BACKGROUND: Novel therapies need to be evaluated in normal clinical practice to allow a true representation of the treatment effectiveness in real-world settings. METHODS/DESIGN: The Salford Lung Study is a pragmatic randomised controlled trial in adult asthma, evaluating the clinical effectiveness and safety of once-daily fluticasone furoate (100 μg or 200 μg)/vilanterol 25 μg in a novel dry-powder inhaler, versus existing asthma maintenance therapy. The study was initiated before this investigational treatment was licensed and conducted in real-world clinical practice to consider adherence, co-morbidities, polypharmacy, and real-world factors...
2015: BMC Pulmonary Medicine
Henriette Steppuhn, Ute Langen, Stephan Mueters, Stefan Dahm, Hildtraud Knopf, Thomas Keil, Christa Scheidt-Nave
OBJECTIVES: In Germany, population-wide data on adherence to national asthma management guidelines are lacking, and performance measures (PM) for quality assurance in asthma care are systematically monitored for patients with German national asthma disease management program (DMP) enrollment only. We used national health survey data to assess variation in asthma care PM with respect to patient characteristics and care context, including DMP enrollment. METHODS: Among adults 18-79 years with self-reported physician-diagnosed asthma in the past 12 months identified from a recent German National Health Interview Survey (GEDA 2010: N = 1096) and the German National Health interview and Examination Survey 2008-2011 (DEGS1: N = 333), variation in asthma care PM was analyzed using logistic regression analysis...
2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
William C Anderson, Stanley J Szefler
Symptomatic asthma in childhood has lifelong effects on lung function and disease severity, emphasizing the need for improved pediatric asthma control. Control of pediatric risk and impairment domains can be achieved through increased medication adherence or new therapeutic strategies. Developing electronic monitoring device technology with reminders might be a key noninvasive resource to address poor adherence in children and adolescents in a clinical setting. In patients who have persistently poor control despite optimal medication compliance, newly emerging pharmaceuticals, including inhaled therapies and biologics, might be key to their treatment...
October 2015: Journal of Allergy and Clinical Immunology
Nicola Scichilone, Andrea Rossi, Andrea Melani
The major influencing factors on persistent asthma control are the selected treatment(s), the drug delivery route and patient's adherence to therapy, together with the influence of lifestyle (i.e. sedentary habit), comorbid conditions and specific asthma phenotypes. Inhaled corticosteroids (ICS) in combination with a long-acting β2-agonist (LABA) are the gold standard for management of persistent asthma, with maximal local targeting and minimal systemic side effects. Several innovative inhaler devices have been developed for effective local drug administration and good patient compliance to therapy...
August 2015: Pulmonary Pharmacology & Therapeutics
Mandeep S Jassal
BACKGROUND: Asthma is among the most common chronic diseases of childhood. Management of pediatric asthma requires an understanding of the issues that uniquely effect children. This review provides the reader with the current state and future directions of pediatric asthma. METHODS: Review of the pediatric asthma literature was undertaken with emphasis on randomized controlled trials and systematic reviews. RESULTS: The prevalence of pediatric asthma remains elevated and is increasingly being appreciated in select global regions...
September 2015: International Forum of Allergy & Rhinology
Helen E Smith, Christina J Jones, Matthew Hankins, Andy Field, Alice Theadom, Richard Bowskill, Rob Horne, Anthony J Frew
OBJECTIVES: Asthma is a chronic condition affecting 300 million people worldwide. Management involves adherence to pharmacological treatments such as corticosteroids and β-agonists, but residual symptoms persist. As asthma symptoms are exacerbated by stress, one possible adjunct to pharmacological treatment is expressive writing (EW). EW involves the disclosure of traumatic experiences which is thought to facilitate cognitive and emotional processing, helping to reduce physiological stress associated with inhibiting emotions...
May 2015: Psychosomatic Medicine
William W Storms, Mike Tringale, Thomas J Ferro
BACKGROUND: Despite the available treatments, asthma remains a serious illness, with a considerable socioeconomic burden associated with a high number of unscheduled visits to the emergency department (ED). Poor adherence and inadequate inhaler technique are contributing factors to poor asthma management and control. OBJECTIVE: The Asthma Inhaler Design Survey assessed the behaviors, attitudes, needs, and preferences of patients with asthma and their caregivers with regard to quick-relief inhaler usage and device design...
July 2015: Allergy and Asthma Proceedings:
Sandra Peláez, Alexandrine J Lamontagne, Johanne Collin, Annie Gauthier, Roland M Grad, Lucie Blais, Kim L Lavoie, Simon L Bacon, Pierre Ernst, Hélène Guay, Martha L McKinney, Francine M Ducharme
BACKGROUND: Although asthma morbidity can be prevented through long-term controller medication, most patients with persistent asthma do not take their daily inhaled corticosteroid. The objective of this study was to gather patients' insights into barriers and facilitators to taking long-term daily inhaled corticosteroids as basis for future knowledge translation interventions. METHODS: We conducted a collective qualitative case study. We interviewed 24 adults, adolescents, or parents of children, with asthma who had received a prescription of long-term inhaled corticosteroids in the previous year...
2015: BMC Pulmonary Medicine
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