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https://www.readbyqxmd.com/read/28214911/-risk-of-pneumonia-in-patients-with-chronic-obstructive-pulmonary-disease-treated-with-inhaled-corticosteroids-evidence-and-uncertainties
#1
Cristoforo Incorvaia, Bruna Gritti, Irene Martignago, Gian Galeazzo Riario-Sforza, Erminia Ridolo
A large number of studies, evaluated by several meta-analyses, indicate that patients with chronic obstructive pulmonary disease (COPD) treated with inhaled corticosteroids have a significantly increased risk of pneumonia which, however, is not associated with a corresponding increase in mortality. The increased risk seems to be exclusive of COPD, since meta-analyses involving patients with asthma treated with inhaled corticosteroids did not show a risk of pneumonia higher than that of the general population...
November 2016: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28211106/a-pilot-randomised-controlled-trial-investigating-a-mediterranean-diet-intervention-in-pregnant-women-for-the-primary-prevention-of-allergic-diseases-in-infants
#2
D A Sewell, V S Hammersley, A Robertson, G Devereux, A Stoddart, C J Weir, A Worth, A Sheikh
BACKGROUND: Observational studies suggest a potentially protective role of the Mediterranean diet (MD) in allergic diseases, including asthma. Large scale randomised controlled trials (RCTs) are needed to test the hypothesised allergy-prevention benefits of a MD during pregnancy. The present two-arm pilot RCT in pregnant women at high-risk of having a child who would develop allergic disease investigated maternal recruitment, retention and acceptability of an MD dietary intervention in the UK...
February 16, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28193465/application-of-human-augmentics-a-persuasive-asthma-inhaler
#3
Brent Grossman, Steve Conner, Giselle Mosnaim, Joshua Albers, Jason Leigh, Steve Jones, Robert Kenyon
This article describes a tailored health intervention delivered on a mobile phone platform, integrating low-literacy design strategies and basic principles of behavior change, to promote increased adherence and asthma control among underserved minority adolescents. We based the intervention and design principles on theories of Human Augmentics and the Elaboration Likelihood Model. We tested the efficacy of using electronic monitoring devices that incorporate informative and persuasive elements to improve adherence to a prescribed daily medication regimen intended to reduce use of asthma rescue medications...
February 10, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28158200/impact-of-online-patient-reminders-to-improve-asthma-care-a-randomized-controlled-trial
#4
Andrew C Pool, Jennifer L Kraschnewski, Jennifer M Poger, Joshua Smyth, Heather L Stuckey, Timothy J Craig, Erik B Lehman, Chengwu Yang, Christopher N Sciamanna
IMPORTANCE: Asthma is one of the most burdensome chronic illnesses in the US. Despite widespread dissemination of evidence-based guidelines, more than half of the adults with asthma have uncontrolled symptoms. OBJECTIVE: To examine the efficacy of an online tool designed to improve asthma control. DESIGN: 12-month single blind randomized controlled trial of the online tool (Intervention condition, IC) versus an active control tool (CC). SETTING: Patients enrolled in an insurance plan...
2017: PloS One
https://www.readbyqxmd.com/read/28148471/a-self-regulation-theory-based-asthma-management-mobile-app-for-adolescents-a-usability-assessment
#5
Adam Sage, Courtney Roberts, Lorie Geryk, Betsy Sleath, Deborah Tate, Delesha Carpenter
BACKGROUND: Self-regulation theory suggests people learn to influence their own behavior through self-monitoring, goal-setting, feedback, self-reward, and self-instruction, all of which smartphones are now capable of facilitating. Several mobile apps exist to manage asthma; however, little evidence exists about whether these apps employ user-centered design processes that adhere to government usability guidelines for mobile apps. OBJECTIVE: Building upon a previous study that documented adolescent preferences for an asthma self-management app, we employed a user-centered approach to assess the usability of a high-fidelity wireframe for an asthma self-management app intended for use by adolescents with persistent asthma...
February 1, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28140625/ncaa-football-off-season-training-unanswered-prayers%C3%A2-a-prayer-answered
#6
Scott Anderson
Off-season training in year-round collegiate football is purported to be performance enhancing. Absent principles of exercise physiology, excesses in sport-training regimens pose risk to the participant athletes. Since 2000, 32 National Collegiate Athletic Association (NCAA) football players have died in sport: 26 nontraumatic deaths and 6 traumatic deaths, a ratio of more than 4 nontraumatic deaths for every traumatic death. On average, 2 NCAA football players die per season played. Best practices, consensus guidelines, and precautions are ignored, elevating the risk...
January 31, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28128966/assessing-patient-and-provider-perceptions-of-factors-associated-with-patient-engagement-in-asthma-care
#7
Tamar Sapir, Kathleen F Moreo, Laurence S Greene, Laura C Simone, Jeffrey D Carter, James J L Mateka, Nicola A Hanania
RATIONALE: National quality improvement initiatives emphasize building partnerships between patients and providers by promoting patient engagement through communication, shared decision-making, and self-care skills. Efforts to promote patient engagement are especially important for people with asthma. To cultivate effective partnerships in asthma care, patients and providers may benefit from understanding each other's values and perceptions regarding treatment goals, shared decision-making, and barriers to optimal care and outcomes...
January 27, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28118240/incorporating-technology-to-advance-asthma-controller-adherence
#8
William C Anderson
PURPOSE OF REVIEW: Technological innovations, including text messaging, smart phone applications, and electronic monitoring devices, aimed at improving asthma controller adherence are being rapidly introduced both into clinical care and directly marketed to patients. This review analyzes recent clinical trials implementing these interventions, with a focus on their benefits and shortcomings. RECENT FINDINGS: Poor medication adherence continues to exert significant morbidity on patients with asthma...
January 21, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28109164/assessment-of-biological-psychological-and-adherence-factors-in-the-prediction-of-step-down-treatment-for-patients-with-well-controlled-asthma
#9
Norihiro Saito, Akihito Kamata, Masamichi Itoga, Mami Tamaki, Hiroyuki Kayaba, Thomas Ritz
OBJECTIVES: Inhaled corticosteroids (ICS) and inhaled corticosteroids combined with long-acting beta2-agonist (ICS/LABA) are standard treatments for asthma. However, factors that might help reduce medication in well-controlled asthma are unknown. We classified problems of asthma patients into biological, psychological and adherence factors, and investigated factors associated with the indication and failure of a medication step-down treatment. METHODS: Two hundred twenty two well-controlled asthma patients receiving ICS or ICS/LABA were assessed for physical and psychiatric problems and followed up for one year from adjustment of their treatment step...
January 21, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28069068/the-sygma-programme-of-phase-3-trials-to-evaluate-the-efficacy-and-safety-of-budesonide-formoterol-given-as-needed-in-mild-asthma-study-protocols-for-two-randomised-controlled-trials
#10
Paul M O'Byrne, J Mark FitzGerald, Nanshan Zhong, Eric Bateman, Peter J Barnes, Christina Keen, Gun Almqvist, Kristine Pemberton, Carin Jorup, Stefan Ivanov, Helen K Reddel
BACKGROUND: In many patients with mild asthma, the low frequency of symptoms and the episodic nature of exacerbations make adherence to regular maintenance treatment difficult. This often leads to over-reliance on short-acting β2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations. The use of budesonide/formoterol 'as needed' in response to symptoms may represent an alternative treatment option for patients with mild asthma...
January 10, 2017: Trials
https://www.readbyqxmd.com/read/28057024/behavior-change-interventions-and-policies-influencing-primary-healthcare-professionals-practice-an-overview-of-reviews
#11
REVIEW
Bhupendrasinh F Chauhan, Maya Jeyaraman, Amrinder Singh Mann, Justin Lys, Becky Skidmore, Kathryn M Sibley, Ahmed Abou-Setta, Ryan Zarychanksi
BACKGROUND: There is a plethora of interventions and policies aimed at changing practice habits of primary healthcare professionals, but it is unclear which are the most appropriate, sustainable, and effective. We aimed to evaluate the evidence on behavior change interventions and policies directed at healthcare professionals working in primary healthcare centers. METHODS: Study design: overview of reviews. DATA SOURCE: MEDLINE (Ovid), Embase (Ovid), The Cochrane Library (Wiley), CINAHL (EbscoHost), and grey literature (January 2005 to July 2015)...
January 5, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28056541/a-randomized-trial-of-user-controlled-text-messaging-to-improve-asthma-outcomes
#12
Maria T Britto, Jennifer M Rohan, Cassandra M Dodds, Terri L Byczkowski
We enrolled 64 patients age 12 to 22 years with a diagnosis of poorly controlled persistent asthma in a 6-month longitudinal crossover study. During the 3 intervention months, participants created personalized text messages to be sent to their phones. Adherence was objectively monitored in 22 of the participants. The adolescent participants gave high ratings on the acceptability of the text messaging system. Asthma control improved from baseline to month 1 regardless of whether teens were in the texting or control group...
January 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28043593/new-approaches-in-drug-treatment-for-tuberculosis-inhalation-using-liposomes-only-a-future-vision-or-soon-in-clinical-practice
#13
Lars-Olof Larsson
A major change of therapy in respiratory medicine has been the transition from oral or parenteral to inhalation therapy, for example, in asthma. Inhalation of anti-infectious drugs has however not a key-role in the treatment of pulmonary infections such as tuberculosis (TB). The inhalation therapy provides several benefits; the target is reached directly with evasion of first-pass metabolism, thereby resulting in reduced systemic side effects. Furthermore, the drug is delivered to an extensive surface area that is rich in lymphoid tissue...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28025241/clinical-tools-to-assess-asthma-control-in-children
#14
Chitra Dinakar, Bradley E Chipps
Asthma affects an estimated 7 million children and causes significant health care and disease burden. The most recent iteration of the National Heart, Lung and Blood Institute asthma guidelines, the Expert Panel Report 3, emphasizes the assessment and monitoring of asthma control in the management of asthma. Asthma control refers to the degree to which the manifestations of asthma are minimized by therapeutic interventions and the goals of therapy are met. Although assessment of asthma severity is used to guide initiation of therapy, monitoring of asthma control helps determine whether therapy should be maintained or adjusted...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/28005003/pleasant-preventing-and-lessening-exacerbations-of-asthma-in-school-age-children-associated-with-a-new-term-a-cluster-randomised-controlled-trial-and-economic-evaluation
#15
Steven A Julious, Michelle J Horspool, Sarah Davis, Mike Bradburn, Paul Norman, Neil Shephard, Cindy L Cooper, W Henry Smithson, Jonathan Boote, Heather Elphick, Amanda Loban, Matthew Franklin, Wei Sun Kua, Robin May, Jennifer Campbell, Rachael Williams, Saleema Rex, Oscar Bortolami
BACKGROUND: Asthma episodes and deaths are known to be seasonal. A number of reports have shown peaks in asthma episodes in school-aged children associated with the return to school following the summer vacation. A fall in prescription collection in the month of August has been observed, and was associated with an increase in the number of unscheduled contacts after the return to school in September. OBJECTIVE: The primary objective of the study was to assess whether or not a NHS-delivered public health intervention reduces the September peak in unscheduled medical contacts...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27979018/patient-adherence-and-effective-communication
#16
Don A Bukstein
BACKGROUND: Poor adherence to inhaled corticosteroid medication is a critical problem for asthma because it contributes to morbidity and mortality through poor asthma control, frequent asthma exacerbations, acute care visits, and oral corticosteroid use. OBJECTIVE: To discuss evidence-based, time-efficient strategies that can be adopted by most practitioners to try to increase patient adherence. METHODS: Asthma management guidelines and other key publications are used to enhance discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27979017/inhalation-devices-delivery-systems-and-patient-technique
#17
Harold S Nelson
BACKGROUND: In real-life clinical settings, physicians often consider the properties of various inhaled corticosteroids (ICSs), but typically little consideration is given to the properties of different inhalers and formulations. OBJECTIVE: To discuss the effects of inhalation devices and user technique on efficacy, safety, and adherence with the aim of improving asthma management. METHODS: Relevant publications were selected to augment discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27971877/evaluation-of-adherence-to-management-guidelines-of-asthmatic-patients-in-greece-and-measures-to-implement-to-achieve-asthma-control
#18
D Kaitelidou, T Katostaras, O Konstantakopoulou, G Angelopoulos, O Siskou, E Tsioni, M Gaga, P Galanis, M Theodorou, G Charalambous, C Lemonidou
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27967215/effects-of-age-and-disease-severity-on-systemic-corticosteroid-responses-in-asthma
#19
Wanda Phipatanakul, David T Mauger, Ronald L Sorkness, Jonathan M Gaffin, Fernando Holguin, Prescott G Woodruff, Ngoc P Ly, Leonard B Bacharier, Nirav R Bhakta, Wendy C Moore, Eugene R Bleecker, Annette T Hastie, Deborah A Meyers, Mario Castro, John Fahy, Anne Fitzpatrick, Benjamin M Gaston, Nizar N Jarjour, Bruce D Levy, Stephen P Peters, W Gerald Teague, Merritt Fajt, Sally E Wenzel, Serpil C Erzurum, Elliot Israel
RATIONALE: Phenotypic distinctions between severe asthma (SA) and non-severe asthma (NONSA) may be confounded by differential adherence or incorrect use of corticosteroids. OBJECTIVES: To determine if there are persistent phenotypic distinctions between SA (as defined by 2014 ATS/ERS guidelines) and NONSA after intramuscular triamcinolone acetonide (TA), and to identify predictors of a corticosteroid response in these populations. METHODS: 526 adults age 18+ years (315 SA) and 188 children, age 6 to <18 years (107 SA) in the NHLBI Severe Asthma Research Program III were characterized before and 3 weeks after TA...
December 14, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27966326/an-assessment-of-adherence-to-asthma-medication-guidelines-findingsfrom-a-tertiary-care-center-in-the-state-of-penang-malaysia
#20
Raja Ahsan Aftab, Amer Hayat Khan, Syed Azhar SYed Sulaiman, Irf Ali, Azmi Hassali, Fahad Saleem
BACKGROUND/AIM: Multiple asthma guidelines have been developed to reduce asthma mortality, morbidity, and cost associated with asthma worldwide. In Malaysia, within this context, it is relatively unknown to what extent doctors adhere to the asthma guidelines. This study aimed to assess guideline adherence and calculate the cost of adhered and nonadhered prescriptions by medical doctors in a public tertiary health care facility. MATERIALS AND METHODS: A cross-sectional study was carried out at Hospital Pulau Pinang, Malaysia...
November 17, 2016: Turkish Journal of Medical Sciences
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