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adherence asthma

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https://www.readbyqxmd.com/read/28069068/the-sygma-programme-of-phase-3-trials-to-evaluate-the-efficacy-and-safety-of-budesonide-formoterol-given-as-needed-in-mild-asthma-study-protocols-for-two-randomised-controlled-trials
#1
Paul M O'Byrne, J Mark FitzGerald, Nanshan Zhong, Eric Bateman, Peter J Barnes, Christina Keen, Gun Almqvist, Kristine Pemberton, Carin Jorup, Stefan Ivanov, Helen K Reddel
BACKGROUND: In many patients with mild asthma, the low frequency of symptoms and the episodic nature of exacerbations make adherence to regular maintenance treatment difficult. This often leads to over-reliance on short-acting β2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations. The use of budesonide/formoterol 'as needed' in response to symptoms may represent an alternative treatment option for patients with mild asthma...
January 10, 2017: Trials
https://www.readbyqxmd.com/read/28057024/behavior-change-interventions-and-policies-influencing-primary-healthcare-professionals-practice-an-overview-of-reviews
#2
REVIEW
Bhupendrasinh F Chauhan, Maya Jeyaraman, Amrinder Singh Mann, Justin Lys, Becky Skidmore, Kathryn M Sibley, Ahmed Abou-Setta, Ryan Zarychanksi
BACKGROUND: There is a plethora of interventions and policies aimed at changing practice habits of primary healthcare professionals, but it is unclear which are the most appropriate, sustainable, and effective. We aimed to evaluate the evidence on behavior change interventions and policies directed at healthcare professionals working in primary healthcare centers. METHODS: Study design: overview of reviews. DATA SOURCE: MEDLINE (Ovid), Embase (Ovid), The Cochrane Library (Wiley), CINAHL (EbscoHost), and grey literature (January 2005 to July 2015)...
January 5, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28056541/a-randomized-trial-of-user-controlled-text-messaging-to-improve-asthma-outcomes
#3
Maria T Britto, Jennifer M Rohan, Cassandra M Dodds, Terri L Byczkowski
We enrolled 64 patients age 12 to 22 years with a diagnosis of poorly controlled persistent asthma in a 6-month longitudinal crossover study. During the 3 intervention months, participants created personalized text messages to be sent to their phones. Adherence was objectively monitored in 22 of the participants. The adolescent participants gave high ratings on the acceptability of the text messaging system. Asthma control improved from baseline to month 1 regardless of whether teens were in the texting or control group...
January 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28043593/new-approaches-in-drug-treatment-for-tuberculosis-inhalation-using-liposomes-only-a-future-vision-or-soon-in-clinical-practice
#4
Lars-Olof Larsson
A major change of therapy in respiratory medicine has been the transition from oral or parenteral to inhalation therapy, for example, in asthma. Inhalation of anti-infectious drugs has however not a key-role in the treatment of pulmonary infections such as tuberculosis (TB). The inhalation therapy provides several benefits; the target is reached directly with evasion of first-pass metabolism, thereby resulting in reduced systemic side effects. Furthermore, the drug is delivered to an extensive surface area that is rich in lymphoid tissue...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28025241/clinical-tools-to-assess-asthma-control-in-children
#5
Chitra Dinakar, Bradley E Chipps
Asthma affects an estimated 7 million children and causes significant health care and disease burden. The most recent iteration of the National Heart, Lung and Blood Institute asthma guidelines, the Expert Panel Report 3, emphasizes the assessment and monitoring of asthma control in the management of asthma. Asthma control refers to the degree to which the manifestations of asthma are minimized by therapeutic interventions and the goals of therapy are met. Although assessment of asthma severity is used to guide initiation of therapy, monitoring of asthma control helps determine whether therapy should be maintained or adjusted...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/28005003/pleasant-preventing-and-lessening-exacerbations-of-asthma-in-school-age-children-associated-with-a-new-term-a-cluster-randomised-controlled-trial-and-economic-evaluation
#6
Steven A Julious, Michelle J Horspool, Sarah Davis, Mike Bradburn, Paul Norman, Neil Shephard, Cindy L Cooper, W Henry Smithson, Jonathan Boote, Heather Elphick, Amanda Loban, Matthew Franklin, Wei Sun Kua, Robin May, Jennifer Campbell, Rachael Williams, Saleema Rex, Oscar Bortolami
BACKGROUND: Asthma episodes and deaths are known to be seasonal. A number of reports have shown peaks in asthma episodes in school-aged children associated with the return to school following the summer vacation. A fall in prescription collection in the month of August has been observed, and was associated with an increase in the number of unscheduled contacts after the return to school in September. OBJECTIVE: The primary objective of the study was to assess whether or not a NHS-delivered public health intervention reduces the September peak in unscheduled medical contacts...
December 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27979018/patient-adherence-and-effective-communication
#7
Don A Bukstein
BACKGROUND: Poor adherence to inhaled corticosteroid medication is a critical problem for asthma because it contributes to morbidity and mortality through poor asthma control, frequent asthma exacerbations, acute care visits, and oral corticosteroid use. OBJECTIVE: To discuss evidence-based, time-efficient strategies that can be adopted by most practitioners to try to increase patient adherence. METHODS: Asthma management guidelines and other key publications are used to enhance discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27979017/inhalation-devices-delivery-systems-and-patient-technique
#8
Harold S Nelson
BACKGROUND: In real-life clinical settings, physicians often consider the properties of various inhaled corticosteroids (ICSs), but typically little consideration is given to the properties of different inhalers and formulations. OBJECTIVE: To discuss the effects of inhalation devices and user technique on efficacy, safety, and adherence with the aim of improving asthma management. METHODS: Relevant publications were selected to augment discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27971877/evaluation-of-adherence-to-management-guidelines-of-asthmatic-patients-in-greece-and-measures-to-implement-to-achieve-asthma-control
#9
D Kaitelidou, T Katostaras, O Konstantakopoulou, G Angelopoulos, O Siskou, E Tsioni, M Gaga, P Galanis, M Theodorou, G Charalambous, C Lemonidou
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27967215/effects-of-age-and-disease-severity-on-systemic-corticosteroid-responses-in-asthma
#10
Wanda Phipatanakul, David T Mauger, Ronald L Sorkness, Jonathan M Gaffin, Fernando Holguin, Prescott G Woodruff, Ngoc P Ly, Leonard B Bacharier, Nirav R Bhakta, Wendy C Moore, Eugene R Bleecker, Annette T Hastie, Deborah A Meyers, Mario Castro, John Fahy, Anne Fitzpatrick, Benjamin M Gaston, Nizar N Jarjour, Bruce D Levy, Stephen P Peters, W Gerald Teague, Merritt Fajt, Sally E Wenzel, Serpil C Erzurum, Elliot Israel
RATIONALE: Phenotypic distinctions between severe asthma (SA) and non-severe asthma (NONSA) may be confounded by differential adherence or incorrect use of corticosteroids. OBJECTIVES: To determine if there are persistent phenotypic distinctions between SA (as defined by 2014 ATS/ERS guidelines) and NONSA after intramuscular triamcinolone acetonide (TA), and to identify predictors of a corticosteroid response in these populations. METHODS: 526 adults age 18+ years (315 SA) and 188 children, age 6 to <18 years (107 SA) in the NHLBI Severe Asthma Research Program III were characterized before and 3 weeks after TA...
December 14, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27966326/an-assessment-of-adherence-to-asthma-medication-guidelines-findingsfrom-a-tertiary-care-center-in-the-state-of-penang-malaysia
#11
Raja Ahsan Aftab, Amer Hayat Khan, Syed Azhar SYed Sulaiman, Irf Ali, Azmi Hassali, Fahad Saleem
BACKGROUND/AIM: Multiple asthma guidelines have been developed to reduce asthma mortality, morbidity, and cost associated with asthma worldwide. In Malaysia, within this context, it is relatively unknown to what extent doctors adhere to the asthma guidelines. This study aimed to assess guideline adherence and calculate the cost of adhered and nonadhered prescriptions by medical doctors in a public tertiary health care facility. MATERIALS AND METHODS: A cross-sectional study was carried out at Hospital Pulau Pinang, Malaysia...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27960229/automated-telephone-communication-systems-for-preventive-healthcare-and-management-of-long-term-conditions
#12
REVIEW
Pawel Posadzki, Nikolaos Mastellos, Rebecca Ryan, Laura H Gunn, Lambert M Felix, Yannis Pappas, Marie-Pierre Gagnon, Steven A Julious, Liming Xiang, Brian Oldenburg, Josip Car
BACKGROUND: Automated telephone communication systems (ATCS) can deliver voice messages and collect health-related information from patients using either their telephone's touch-tone keypad or voice recognition software. ATCS can supplement or replace telephone contact between health professionals and patients. There are four different types of ATCS: unidirectional (one-way, non-interactive voice communication), interactive voice response (IVR) systems, ATCS with additional functions such as access to an expert to request advice (ATCS Plus) and multimodal ATCS, where the calls are delivered as part of a multicomponent intervention...
14, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27942102/quality-of-acute-asthma-care-in-two-tertiary-hospitals-in-a-state-in-south-western-nigeria-a-report-of-clinical-audit
#13
Olufemi Olumuyiwa Desalu, Adekunle Olatayo Adeoti, Olarinde Jeffrey Ogunmola, Joseph Olusesan Fadare, Tolutope Fasanmi Kolawole
BACKGROUND: To audit the quality of acute asthma care in two tertiary hospitals in a state in the southwestern region of Nigeria and to compare the clinical practice against the recommendations of the Global Initiative for Asthma (GINA) guideline. PATIENTS AND METHODS: We carried out a retrospective analysis of 101 patients who presented with acute exacerbation of asthma to the hospital between November 2010 and October 2015. RESULTS: Majority of the cases were females (66...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27941744/assessing-attitudes-and-perceptions-of-obstructive-pulmonary-disease-patients-towards-inhaler-therapy-in-a-low-income-country-a-cross-sectional-study
#14
M Z Farooq, W Waqar, M Mustaqeem, M S Farooq, J A Khan, M Hassan
Chronic respiratory diseases (CRD) like asthma and chronic obstructive pulmonary disease (COPD) are one of the leading causes of morbidity and mortality worldwide. A patient's perception, about his or her medicine, may have an impact on adherence to medications. The purpose was to assess the attitudes and perceptions, regarding inhaler therapy use, among patients with obstructive pulmonary disease in Pakistan, a developing country. With a questionnaire developing this cross-sectional study was conducted at the Department of Medicine's outpatient clinic at Civil Hospital, Karachi from October 2013 to January 2014...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27940683/modification-of-an-established-pediatric-asthma-pathway-improves-evidence-based-efficient-care
#15
Lori Rutman, Robert C Atkins, Russell Migita, Jeffrey Foti, Suzanne Spencer, K Casey Lion, Davene R Wright, Michael G Leu, Chuan Zhou, Rita Mangione-Smith
OBJECTIVE: In September 2011, an established pediatric asthma pathway at a tertiary care children's hospital underwent significant revision. Modifications included simplification of the visual layout, addition of evidence-based recommendations regarding medication use, and implementation of standardized admission criteria. The objective of this study was to determine the impact of the modified asthma pathway on pathway adherence, percentage of patients receiving evidence-based care, length of stay, and cost...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27933151/improving-asthma-care-in-a-pediatric-resident-clinic
#16
Julia Lee, Albina Gogo, Daniel Tancredi, Erik Fernandez Y Garcia, Ulfat Shaikh
There is variation in pediatric asthma management in the outpatient setting. Adherence to national asthma guidelines provides a systematic standardized approach to asthma management. There is a gap between usual and guideline-consistent asthma care in resident clinics. Practice improvement modules aimed at improving resident physician adherence to asthma care guidelines have not been consistently utilized and have not yet been studied. Our aim was to increase guideline consistent care in our pediatric resident clinic in a twelve-month period via increasing performance on the following measures to 75%: spirometry testing; influenza immunization recommendation; level of control assessed through the use of a standardized questionnaire; appropriate medications per national guideline; and use of written asthma action plans...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27933034/a-novel-molybdenum-containing-methionine-sulfoxide-reductase-supports-survival-of-haemophilus-influenzae-in-an-in-vivo-model-of-infection
#17
Rabeb Dhouib, Dk Seti Maimonah Pg Othman, Victor Lin, Xuanjie J Lai, Hewa G S Wijesinghe, Ama-Tawiah Essilfie, Amanda Davis, Marufa Nasreen, Paul V Bernhardt, Philip M Hansbro, Alastair G McEwan, Ulrike Kappler
Haemophilus influenzae is a host adapted human mucosal pathogen involved in a variety of acute and chronic respiratory tract infections, including chronic obstructive pulmonary disease and asthma, all of which rely on its ability to efficiently establish continuing interactions with the host. Here we report the characterization of a novel molybdenum enzyme, TorZ/MtsZ that supports interactions of H. influenzae with host cells during growth in oxygen-limited environments. Strains lacking TorZ/MtsZ showed a reduced ability to survive in contact with epithelial cells as shown by immunofluorescence microscopy and adherence/invasion assays...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27932381/improving-the-efficiency-of-care-for-pediatric-patients-hospitalized-with-asthma
#18
Kathleen W Bartlett, Victoria M Parente, Vanessa Morales, Jillian Hauser, Heather S McLean
BACKGROUND: Asthma exacerbations are a leading cause of hospitalization among children. Despite the existence of national pediatric asthma guidelines, significant variation in care persists. At Duke Children's Hospital, we determined that our average length of stay (ALOS) and cost for pediatric asthma admissions exceeded that of our peers. Our aim was to reduce the ALOS of pediatric patients hospitalized with asthma from 2.9 days to 2.6 days within 12 months by implementing an asthma pathway within our new electronic health record...
January 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/27923862/use-of-a-motivational-interviewing-informed-strategy-in-group-orientations-to-improve-retention-and-intervention-attendance-in-a-randomized-controlled-trial
#19
Lan Xiao, Nan Lv, Lisa G Rosas, Shweta Karve, Veronica Luna, Elizabeth Jameiro, Nancy Wittels, Jun Ma
High retention and treatment adherence are essential to ensure the quality of evidence from clinical trials. Strategies for improving these have been explored but actual rates in lifestyle intervention trials indicate challenges. This study examined the use of a motivational interviewing-informed strategy during interactive group orientations prior to obtaining informed consent, collecting baseline data and randomization in a healthy dietary pattern intervention trial for asthma control in adults. The themes generated from small group discussions and echoed in large group discussions during the orientation sessions helped potential participants better understand the scientific rationale of the research design and procedures and the practical implications for them to participate in the study...
December 2016: Health Education Research
https://www.readbyqxmd.com/read/27916463/how-does-patient-provider-communication-influence-adherence-to-asthma-medications
#20
Henry N Young, Maria E Len-Rios, Roger Brown, Megan M Moreno, Elizabeth Cox
OBJECTIVE: To assess hypothesized pathways through which patient-provider communication impacts asthma medication adherence. METHODS: A national sample of 452 adults with asthma reported assessments of patient-provider communication, proximal outcomes (understanding of asthma self-management, patient-provider agreement, trust in the clinician, involvement in care, motivation), and adherence to asthma medications. Structural equation modeling was used to examine hypothesized pathways...
November 28, 2016: Patient Education and Counseling
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