Kai Luo, Brandilyn A Peters, Jee-Young Moon, Xiaonan Xue, Zheng Wang, Mykhaylo Usyk, David B Hanna, Alan L Landay, Michael F Schneider, Deborah Gustafson, Kathleen M Weber, Audrey French, Anjali Sharma, Kathryn Anastos, Tao Wang, Todd Brown, Clary B Clish, Robert C Kaplan, Rob Knight, Robert D Burk, Qibin Qi
BACKGROUND: Gut dysbiosis has been linked with both HIV infection and diabetes, but its interplay with metabolic and inflammatory responses in diabetes, particularly in the context of HIV infection, remains unclear. METHODS: We first conducted a cross-sectional association analysis to characterize the gut microbial, circulating metabolite, and immune/inflammatory protein features associated with diabetes in up to 493 women (~ 146 with prevalent diabetes with 69...
April 20, 2024: Genome Medicine