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https://www.readbyqxmd.com/read/28097841/oxygen-saturation-periodic-breathing-and-sleep-apnea-in-infants-aged-1-4-months-old-living-at-3200-meters-above-sea-level
#1
Santiago Ucrós, Claudia Granados, Karem Parejo, Fausto Ortega, Fernando Guillén, Sonia Restrepo, Fabián Gil, Miriam Guillén
OBJECTIVES: To describe, in infants aged 1-4 months old living at 3200 meters above sea level (MASL), oxygen saturation (SpO2), sleep apnea indices, and periodic breathing (PB) during sleep. Polysomnographies were done in 18 healthy infants. RESULTS: The median SpO2 was 87%, and the median PB was 7.2% for the total sleep time. The median central sleep apnea index was 30.5/hour, which decreased to 5.4/hour once sleep apneas associated with PB were excluded. The 5th percentile for SpO2 was 76% among awake infants, and 66% among asleep infants...
February 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28096239/skin-to-skin-care-in-preterm-infants-receiving-respiratory-support-does-not-lead-to-physiological-instability
#2
Laila Lorenz, Jennifer A Dawson, Hannah Jones, Susan E Jacobs, Jeanie L Cheong, Susan M Donath, Peter G Davis, C Omar F Kamlin
OBJECTIVE: Providing skin-to-skin care (SSC) to preterm infants is standard practice in many neonatal intensive care units. There are conflicting reports on the stability of oxygen saturation (SpO2) during SSC, which may create a barrier to a wider implementation of SSC to infants receiving respiratory support. Regional cerebral oxygenation (rcO2) measured using near-infrared spectroscopy can serve as a surrogate parameter for cerebral oxygen delivery and consumption. We hypothesised that rcO2 during SSC would be similar to standard care in preterm infants receiving respiratory support...
January 17, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28096039/the-impact-of-emergency-medical-services-in-acute-heart-failure
#3
Pia Harjola, James Boyd, Tuukka Tarvasmäki, Juho Mattila, Reijo Koski, Markku Kuisma, Veli-Pekka Harjola
BACKGROUND: Real-life data on the role of emergency medical services (EMS) in acute heart failure (AHF) are scarce. Our aim was to describe prehospital treatment of AHF and to compare patients using EMS with self-presented, non-EMS patients. METHODS: Data were collected retrospectively from three university hospitals in Helsinki metropolitan area between July 1, 2012 and July 31, 2013. According to the use of EMS, patients were divided into EMS and non-EMS groups...
January 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28093005/cardiac-and-respiratory-effects-of-deep-regional-hyperthermia-using-an-8-mhz-radiofrequency-capacitive-device-on-patients-with-cancer
#4
Rieko Izukura, Hajime Imada, Nobuko Hashiguchi, Hiroyuki Sawatari, Takayuki Ohguri, Mami Miyazono, Shin Ohta, Chizuko Takakura, Keiko Yamasaki, Chie Magota, Kanae Fujita, Hiromi Kuroda, Hideki Hirata, Tomoko Ohkusa, Akiko Chishaki
PURPOSE: Hyperthermia (HT), an adjuvant therapy for variable cancers, may cause physiological changes in the patients, which may lead to cardiovascular problems. Among various HT treatments, the physiological effects of deep regional HT are still unclear. We examined the physiological alterations throughout deep regional HT to improve the HT safety. MATERIALS AND METHODS: Thirty-one patients (age: 61±12 years) with cancer received HT in the thoracic or upper abdominal regions using an 8-MHz radiofrequency-capacitive-device for 50 min...
January 16, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28091858/will-wearing-dentures-affect-edentulous-patients-breathing-during-sleep
#5
Qiuwen Chen, Dong Zou, Hailan Feng, Shaoxia Pan
PURPOSES: The purpose of this study is to investigate the effect of wearing dentures on obstructive sleep apnea and hypopnea among completely edentulous patients. METHODS AND MATERIALS: A self-controlled study was conducted among 30 edentulous patients. Polysomnograms were recorded in the sleep laboratory on two consecutive nights. Participants slept with their dentures in one night and without dentures in the other. The apnea and hypopnea index (AHI), lowest oxygen saturation (L-SpO2), and morning blood pressure (MBP) were collected for statistical analysis...
January 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28090054/hemoglobin-kansas-as-a-rare-cause-of-cyanosis-a-case-report-and-review-of-the-literature
#6
Yoshikuni Nagayama, Minoru Yoshida, Tadashi Kohyama, Katsuyuki Matsui
Hemoglobin (Hb) Kansas is an inherited Hb variant with a low oxygen affinity that is associated with low oxygen saturation on pulse oximetry (SpO2). It leads to asymptomatic cyanosis. Patients with Hb Kansas do not require any specific treatment and the prognosis is good. In patients with unexplained cyanosis, we should thus consider Hb variants, including Hb Kansas and avoid unnecessary investigations and managements. We herein report the case of 65-year-old woman with Hb Kansas and review five other cases (three lineages) that have been reported in Japan...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28088956/-thoracic-paravertebral-block-in-the-pacu-for-immediate-postoperative-pain-relief-after-video-assisted-thoracoscopic-surgery
#7
F Liu, J Zhang, H K Zhang, Y Q Zhao, P Liang, Y X Zuo
Objective: To investigate the effectiveness and safety of the thoracic paravertebral block(TPVB) in the post postanesthesia care unit(PACU) for patients suffered moderate to severe pain after Video-Assisted Thoracoscopic Surgery(VATS). Methods: 78 atients who complained moderate to severe pain on arrival to PACU after VATS were randomly assigned into two groups: thoracic paravertebral block treatment group(P group) and sufentanil treatment group(S group). The VAS Pain score at rest and movement, heart rate, blood pressure, and pulse oximetry 1 hour after treatment and duration of patients staying in the PACU after treatment were recorded...
January 10, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28087818/three-hours-of-intermittent-hypoxia-increases-circulating-glucose-levels-in-healthy-adults
#8
Lauren P Newhouse, Michael J Joyner, Timothy B Curry, Marcello C Laurenti, Chiara Dalla Man, Claudio Cobelli, Adrian Vella, Jacqueline K Limberg
An independent association exists between sleep apnea and diabetes. Animal models suggest exposure to intermittent hypoxia, a consequence of sleep apnea, results in altered glucose metabolism and fasting hyperglycemia. However, it is unknown if acute exposure to intermittent hypoxia increases glucose concentrations in nondiabetic humans. We hypothesized plasma glucose would be increased from baseline following 3 h of intermittent hypoxia in healthy humans independent of any effect on insulin sensitivity. Eight (7M/1F, 21-34 years) healthy subjects completed two study visits randomized to 3 h of intermittent hypoxia or continuous normoxia, followed by an oral glucose tolerance test...
January 2017: Physiological Reports
https://www.readbyqxmd.com/read/28081144/digital-health-tracking-physiomes-and-activity-using-wearable-biosensors-reveals-useful-health-related-information
#9
Xiao Li, Jessilyn Dunn, Denis Salins, Gao Zhou, Wenyu Zhou, Sophia Miryam Schüssler-Fiorenza Rose, Dalia Perelman, Elizabeth Colbert, Ryan Runge, Shannon Rego, Ria Sonecha, Somalee Datta, Tracey McLaughlin, Michael P Snyder
A new wave of portable biosensors allows frequent measurement of health-related physiology. We investigated the use of these devices to monitor human physiological changes during various activities and their role in managing health and diagnosing and analyzing disease. By recording over 250,000 daily measurements for up to 43 individuals, we found personalized circadian differences in physiological parameters, replicating previous physiological findings. Interestingly, we found striking changes in particular environments, such as airline flights (decreased peripheral capillary oxygen saturation [SpO2] and increased radiation exposure)...
January 2017: PLoS Biology
https://www.readbyqxmd.com/read/28079763/the-comparison-of-etomidate-and-propofol-anesthesia-in-patients-undergoing-gastrointestinal-endoscopy-a-systematic-review-and-meta-analysis
#10
Limin Ye, Xiangyang Xiao, Liyi Zhu
INTRODUCTION: Etomidate and propofol played an important role in the sedation of patients undergoing gastrointestinal endoscopy. We conducted a systematic review and meta-analysis to compare their efficacy and safety. MATERIALS AND METHODS: PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials assessing the effect of etomidate versus propofol for the anesthesia of patients undergoing gastrointestinal endoscopy were included...
January 10, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28068656/mechanisms-of-improved-exercise-performance-under-hyperoxia
#11
Silvia Ulrich, Elisabeth D Hasler, Séverine Müller-Mottet, Stephan Keusch, Michael Furian, Tsogyal D Latshang, Simon Schneider, Stéphanie Saxer, Konrad E Bloch
BACKGROUND: The impact of hyperoxia on exercise limitation is still incompletely understood. OBJECTIVES: We investigated to which extent breathing hyperoxia enhances the exercise performance of healthy subjects and which physiologic mechanisms are involved. METHODS: A total of 32 healthy volunteers (43 ± 15 years, 12 women) performed 4 bicycle exercise tests to exhaustion with ramp and constant-load protocols (at 75% of the maximal workload [Wmax] on FiO2 0...
January 10, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28066591/relationship-between-polycythemia-and-in-hospital-mortality-in-chronic-obstructive-pulmonary-disease-patients-with-low-risk-pulmonary-embolism
#12
Lu Guo, Aamer Rasheed Chughtai, Hongli Jiang, Lingyun Gao, Yan Yang, Yang Yang, Yuejian Liu, Zhenliang Xie, Weimin Li
BACKGROUNDS: Pulmonary embolism (PE) is frequent in subjects with chronic obstructive pulmonary disease (COPD) and associated with high mortality. This multi-center retrospective study was performed to investigate if secondary polycythemia is associated with in-hospital mortality in COPD patients with low-risk PE. METHODS: We identified COPD patients with proven PE between October, 2005 and October, 2015. Patients in risk classes III-V on the basis of the PESI score were excluded...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28063687/the-longitudinal-effects-of-persistent-apnea-on-cerebral-oxygenation-in-infants-born-preterm
#13
Rosemary S C Horne, Annie C H Fung, Scott NcNeil, Karinna L Fyfe, Alexsandria Odoi, Flora Y Wong
OBJECTIVE: To assess the incidence and impact of persistent apnea on heart rate (HR), oxygen saturation (SpO2), and brain tissue oxygenation index (TOI) over the first 6 months after term equivalent age in ex-preterm infants. STUDY DESIGN: Twenty-four preterm infants born between 27 and 36 weeks of gestational age were studied with daytime polysomnography at 2-4 weeks, 2-3 months, and 5-6 months post-term corrected age. Apneas lasting ≥3 seconds were included and maximal percentage changes (nadir) in HR, SpO2, and tissue oxygenation index (TOI, NIRO-200 Hamamatsu) from baseline were analyzed...
January 4, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28061836/end-tidal-capnographic-monitoring-to-detect-apnea-episodes-during-flexible-bronchoscopy-under-sedation
#14
Tsukasa Ishiwata, Kenji Tsushima, Mai Fujie, Kenichi Suzuki, Kosuke Hirota, Mitsuhiro Abe, Naoko Kawata, Jiro Terada, Koichiro Tatsumi
BACKGROUND: Apnea developing as a result of oversedation is a potential clinical problem in patients undergoing flexible bronchoscopy (FB) under sedation. However, there are no reports of evaluation using a standardized method of the frequency of occurrence of apnea episodes during FB under sedation. The aim of this study was to investigate the frequency of apnea episodes during FB under sedation in the clinical setting by end-tidal capnography. METHODS: This study was a single-institution retrospective review of a prospectively maintained database and medical records, including capnographic data, from April 2015 to March 2016...
January 7, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28051570/severe-hypoxemia-in-muskoxen-ovibos-moschatus-immobilized-with-etorphine-and-xylazine-corrected-with-supplemental-nasal-oxygen
#15
Marianne Lian, Sven Björck, Jon M Arnemo, Núria Fandos Esteruelas, Martine Angel, Solveig C Minsaas, Krista L Jones, Alina L Evans
Twenty-three muskoxen ( Ovibos moschatus ) housed in a captive facility for rewilding in Sweden were chemically immobilized for annual health evaluations and hoof trimming. The muskoxen were darted in May to September (2012-2015) in their holding pen with etorphine (0.015 mg/kg) and xylazine (0.1 mg/kg) intramuscularly. Twenty-two of the 23 animals were immobilized with a single dart injection. The mean (SD) induction time was 4 (2) min. Arterial blood gases were collected from 18 animals. All animals were severely hypoxemic with varying degrees of respiratory acidosis...
January 4, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28050480/comparison-of-dexmedetomidine-propofol-versus-fentanyl-propofol-on-insertion-conditions-of-proseal-laryngeal-mask-airway
#16
Shalaka Sandeep Nellore, Abhijeet Dattatray Waychal, Preeti Sachin Rustagi
INTRODUCTION: Proseal Laryngeal Mask Airway (PLMA) is a newer supraglottic airway device that requires adequate depth of anaesthesia and suppression of upper airway reflexes thereby providing optimal insertion conditions. AIM: To compare dexmedetomidine and fentanyl for co-induction with propofol with respect to PLMA insertion conditions, haemodynamic variation and the total dose requirement of propofol. MATERIALS AND METHODS: This was a prospective randomized double-blinded study conducted in 60 cases of American Society of Anaesthesiologists (ASA) class I/II undergoing elective surgery under general anaesthesia...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28048853/su-f-p-14-oxygen-inhalation-should-be-the-conventional-approach-in-the-treatment-of-thoracic-and-abdominal-cancer-by-radiotherapy-with-active-breathing-control-abc
#17
G Gong, Y Guo, Y Yin
PURPOSE: To investigate the feasibility and potential benefit of oxygen inhalation (OI) during radiotherapy applying an active breathing control (ABC) device, by analyzing the blood oxygen saturation (SpO2) and the instantaneous heart rate (IHR) variation in breath holding with OI and oxygen non-inhalation (ONI). METHODS: The 27 healthy volunteers (16 males, 11 females) who were involved in this trial were all required to hold their breath for 10 times, non-inhaling and inhaling oxygen successively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045995/analysis-of-hypoxic-and-hypercapnic-ventilatory-response-in-healthy-volunteers
#18
Shmuel Goldberg, Hanna Maria Ollila, Ling Lin, Husham Sharifi, Tom Rico, Olivier Andlauer, Adi Aran, Efrat Bloomrosen, Juliette Faraco, Han Fang, Emmanuel Mignot
INTRODUCTION: A previous study has suggested that the Human Leukocyte Antigen (HLA) allele DQB1*06:02 affects hypoxic ventilatory response (HVR) but not hypercapnic ventilatory response (HCVR) in an Asian population. The current study evaluated the relationship in Caucasians and Asians. In addition we assessed whether gender or polymorphisms in genes participating in the control of breathing affect HVR and HCVR. METHODS: A re-breathing system was used to measure HVR and HCVR in 551 young adults (56...
2017: PloS One
https://www.readbyqxmd.com/read/28033078/the-accuracy-of-noninvasive-peripheral-pulse-oximetry-after-palliative-cardiac-surgery-in-patients-with-cyanotic-congenital-heart-disease
#19
Gemma E Scrimgeour, Michael J Griksaitis, John V Pappachan, Andrew J Baldock
BACKGROUND: Children with cyanotic congenital heart disease (CCHD) live with oxyhemoglobin saturations that are typically expressed as percentages in the range of 70s and 80s. Peripheral pulse oximetry (measurement of SpO2) performs poorly in this range and yet is widely used to inform clinical decisions in these patients. The reference standard is co-oximetry of arterial samples (SaO2). METHODS: In this study, 515 paired measurements of SpO2 and SaO2 were taken from 19 children who had undergone palliative cardiac surgery...
January 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28013253/factors-affecting-the-target-oxygen-saturation-in-the-first-minutes-of-life-in-preterm-infants
#20
Sinan Uslu, Umut Zubarioglu, Sehrinaz Sozeri, Mesut Dursun, Ali Bulbul, Evrim Kiray Bas, Ebru Turkoglu Unal, Aysegul Uslu
BACKGROUND: The aim of this study was to describe the effect of factors on time to reach a pulse oxygen saturation (SpO2) level of 90% in preterm infants in the delivery room. METHODS: Preterm (<35 gestational age) infants who did not require supplemental oxygen were included in the study. Continuous recordings were taken by pulse oximetry during the first 15 min of life. RESULTS: Of 151 preterm infants, 79 (52.3%) were female and 126 (83...
December 24, 2016: Journal of Tropical Pediatrics
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