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https://www.readbyqxmd.com/read/29467516/packed-red-blood-cells-transfusion-in-neonates-effect-on-fio-2-and-pao-2-sao-2-ratio-and-implications-for-neonatal-saturation-targeting
#1
Itamar Nitzan, Cathy Hammerman, Francis B Mimouni, Alona Bin-Nun
OBJECTIVE: To assess the effect of blood transfusions in neonates on partial pressure of oxygen in arterial blood (PaO2 ), arterial hemoglobin oxygen saturation (SaO2 ) and arterial hemoglobin oxygen saturation as measured by pulse oximetry (SpO2 ). STUDY DESIGN: Retrospective study of neonates that received a first blood transfusion while having an indwelling arterial line. We compared PaO2 , SaO2, SpO2, SaO2 /PaO2 ratio and fraction of inspired oxygen (FiO2 ) 12 h before and after blood transfusion...
February 21, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29452603/the-effects-of-desflurane-and-sevoflurane-on-nesfatin-1-levels-in-laparoscopic-cholecystectomy-a-randomized-controlled-trial
#2
A T D Ozcan, C B Altin, S Erdogan, M Ergin, A Çiftçi, H Kara, S M Aksoy, A But
BACKGROUND: Nesfatin-1 is involved in cardiovascular regulation, stress-related responses. The objective of this study is to investigate the impact of volatile anesthetics on Nesfatin-1 levels. METHOD: Fourty-two patients aged 30-65 years with the American Society Anesthesiology (ASA) Class I-II who were scheduled for laparoscopic cholecystectomy were included in the study Patients were randomized into two group; desflurane administered group (Group I, n = 21) and sevoflurane administered group (Group II, n = 21)...
February 16, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29442057/inguinal-hernia-repair-in-day-surgery-the-role-of-mac-monitored-anesthesia-care-with-remifentanil
#3
P Palumbo, S Usai, C Amatucci, B Perotti, L Ruggeri, G Illuminati, G Tellan
BACKGROUND: The extension of indications for procedures in a Day Surgery (DS) setting has led to changes in the anesthetic and surgical treatment of Inguinal Hernias (IH). According to the recommendations of the European Hernia Society, the treatment of IH in DS units should be performed under Monitored Anesthesia Care (MAC). PATIENTS AND METHODS: 960 patients underwent IH repairs over a period of 24 months. The patients were randomly divided into two groups: R (remifentanil) and F (fentanyl); the group F was considered as a control group...
November 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29441909/the-effect-of-continuous-perfusion-of-esmolol-on-cardiovascular-risk-in-elderly-patients-undergoing-noncardiac-surgery
#4
X K Zhang, Q Hu, Q H Chen, W X Wang
We evaluated the effect of continuous perfusion of esmolol on cardiovascular risk during curative laparoscopic surgery for gastrointestinal cancer in elderly patients. Sixty patients with gastrointestinal cancer, aged from 60 to 80 years, were divided into an esmolol group (ES, n = 30) and a control group (NS, n = 30). ES patients were treated with esmolol at a dose of 0.3 mg/kg 3 min before tracheal intubation, and received continuous perfusion of esmolol at a dose of 50 μg/kg/min during operation. In NS, esmolol was replaced by saline...
August 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29428066/utility-of-bispectrum-in-the-screening-of-pediatric-sleep-apnea-hypopnea-syndrome-using-oximetry-recordings
#5
Fernando Vaquerizo-Villar, Daniel Álvarez, Leila Kheirandish-Gozal, Gonzalo César Gutiérrez-Tobal, Verónica Barroso-García, Andrea Crespo, Félix Del Campo, David Gozal, Roberto Hornero
BACKGROUND AND OBJECTIVE: The aim of this study was to assess the utility of bispectrum-based oximetry approaches as a complementary tool to traditional techniques in the screening of pediatric sleep apnea-hypopnea syndrome (SAHS). METHODS: 298 blood oxygen saturation (SpO 2 ) signals from children ranging 0-13 years of age were recorded during overnight polysomnography (PSG). These recordings were divided into three severity groups according to the PSG-derived apnea hypopnea index (AHI): AHI < 5 events per hour (e/h), 5 ≤ AHI < 10 e/h, AHI ≥ 10 e/h...
March 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29427527/ubc-nepal-expedition-the-use-of-oral-antioxidants-does-not-alter-cerebrovascular-function-at-sea-level-or-high-altitude
#6
Alex B Hansen, Ryan L Hoiland, Nia C S Lewis, Michael M Tymko, Joshua C Tremblay, Michael Stembridge, Daniela Nowak-Flück, Howard H Carter, Damian M Bailey, Philip N Ainslie
Hypoxia is associated with an increased systemic and cerebral formation of free radicals and associated reactants that may be linked to impaired cerebral vascular function a neurological sequela. To what extent oral antioxidants prophylaxis impacts cerebrovascular function in humans throughout the course of acclimatization to the hypoxia of terrestrial high-altitude has not been examined. Thus, the purpose of the current study was to examine the influence of orally ingested antioxidants at clinically relevant doses (vitamin C, E, and alpha-lipoic acid) on cerebrovascular regulation at sea-level (344 m; n = 12; female n = 2 participants), and at high altitude (5050 m; n = 9; female n = 2), in a randomized, placebo-controlled, and double-blinded crossover design...
February 10, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29415185/induced-sputum-as-a-diagnostic-tool-in-pneumonia-in-under-five-children-a-hospital-based-study
#7
Aditya Kurade, Sara Dhanawade, Sachin Shetti
Objective: The objective of this articlewas to study the success, tolerability of sputum induction and the bacterial isolates of induced sputum in children aged <5 years. Methods: The cross-sectional study included 120 hospitalized children aged 1-59 months meeting WHO criteria for pneumonia. Sputum induction was performed using hypertonic (3%) saline. Results: Mean age of the subjects was 19.5 months (2-59 months). Overall success of sputum induction was 53...
February 5, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29414453/physiological-predictors-of-hypoxic-challenge-testing-hct-outcomes-in-interstitial-lung-disease-ild
#8
Shaney L Barratt, Jonathon Shaw, Rachel Jones, Anna Bibby, Huzaifa Adamali, Naveed Mustfa, Ian Cliff, Helen Stone, Nazia Chaudhuri
BACKGROUND: Pre-flight risk assessments are currently recommended for all Interstitial Lung Disease (ILD) patients. Hypoxic challenge testing (HCT) can inform regarding the need for supplemental in-flight oxygen but variables which might predict the outcome of HCT and thus guide referral for assessment, are unknown. METHODS: A retrospective analysis of ILD patients attending for HCT at three tertiary care ILD referral centres was undertaken to investigate the concordance between HCT and existing predictive equations for prediction of in-flight hypoxia...
February 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29400616/repeated-sprint-training-in-hypoxia-induced-by-voluntary-hypoventilation-improves-running-repeated-sprint-ability-in-rugby-players
#9
Charly Fornasier-Santos, Grégoire P Millet, Xavier Woorons
PURPOSE: The goal of this study was to determine the effects of repeated-sprint training in hypoxia induced by voluntary hypoventilation at low lung volume (VHL) on running repeated-sprint ability (RSA) in team-sport players. METHODS: Twenty-one highly trained rugby players performed, over a 4-week period, seven sessions of repeated 40-m sprints either with VHL (RSH-VHL, n = 11) or with normal breathing (RSN, n = 10). Before (Pre-) and after training (Post-), performance was assessed with an RSA test (40-m all-out sprints with a departure every 30 s) until task failure (85% of the reference velocity assessed in an isolated sprint)...
February 5, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29391879/combined-acupuncture-and-general-anesthesia-on-immune-and-cognitive-function-in-elderly-patients-following-subtotal-gastrectomy-for-gastric-cancer
#10
Ningke Wang, Yangwen Ou, Wenxiang Qing
This study investigated the effects of acupuncture combined with general anesthesia on postoperative immune and cognitive functions in elderly patients undergoing subtotal gastrectomy. We recruited 96 elderly patients who received anesthesia for subtotal gastrectomy and randomly divided them into control (n=48) and experimental (n=48) groups. The control group received general anesthesia and the experimental group received combined acupuncture and general anesthesia. We measured hemodynamic immediately before and after anesthesia induction, and immune observations before and after surgery...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29391372/normal-saline-instillation-versus-no-normal-saline-instillation-and-lung-recruitment-versus-no-lung-recruitment-with-paediatric-endotracheal-suction-the-nares-trial-a-study-protocol-for-a-pilot-factorial-randomised-controlled-trial
#11
Jessica A Schults, Marie Cooke, Debbie A Long, Andreas Schibler, Robert S Ware, Marion L Mitchell
INTRODUCTION: Endotracheal suction (ETS) is a frequent and necessary airway intervention for the intubated child. The aim of ETS is to clear the endotracheal tube and airways of respiratory secretions; however, the methods of performing ETS are varied. Internationally a number of ETS treatments are in use. Many have not been rigorously evaluated in a randomised controlled trial setting, and it is uncertain whether any are associated with better outcomes for the critically ill child. With approximately 50% of paediatric intensive care admissions requiring intubation, ETS interventions that maximise the efficacy and minimise the complications of ETS could translate to improved health for substantial numbers of critically ill children, and significant cost savings...
January 31, 2018: BMJ Open
https://www.readbyqxmd.com/read/29391159/cricothyroid-membrane-puncture-guided-tracheostomy-a-new-technique-for-emergency-airway-access
#12
Youbai Chen, Yan Han, Meredith August, Nalton F Ferraro, Qixu Zhang, Haizhong Zhang
PURPOSE: We sought to compare cricothyroid membrane puncture-guided tracheostomy (CMPGT) with surgical cricothyroidotomy (SC) and percutaneous tracheostomy with Griggs' guidewire dilating forceps (GWDF) for establishing an emergency airway in a porcine model. We hypothesized that CMPGT would be associated with a shorter time to ventilation and more rapid restoration of oxygenation. MATERIALS AND METHODS: We implemented a small pilot animal study. Eighteen miniature pigs were randomly assigned to undergo CMPGT, SC, or GWDF...
January 9, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29383314/controlled-vs-spontaneous-ventilation-for-bronchoscopy-in-children-with-tracheobronchial-foreign-body
#13
Leila Mashhadi, Alireza Sabzevari, Mohammad Gharavi Fard, Reza Shojaeian, Maryam Salehi, Marjan Joodi, Mahdi Fathi, Ali Jafarzadeh Esfehani, Kamran Khazaeni
Introduction: Tracheobronchial foreign body aspiration is a common life-threatening condition in children. There are controversies in the management of this condition, including the type of ventilation during bronchoscopy. This study aims to compare anesthesia with controlled ventilation versus spontaneous ventilation in rigid bronchoscopy in children with foreign body aspiration. Materials and Methods: Patients who were candidates for rigid bronchoscopy due to foreign body aspiration were randomly assigned to either anesthesia with spontaneous ventilation or controlled ventilation...
November 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29382993/-c-omparative-evaluation-of-the-intranasal-spray-formulation-of-midazolam-and-dexmedetomidine-in-patients-undergoing-surgical-removal-of-impacted-mandibular-third-molars-a-split-mouth-prospective-study
#14
Shashank Hiwarkar, Rajesh Kshirsagar, Vikram Singh, Amod Patankar, Sanjay Chandan, Mukund Rathod, Ajay Mohite
Purpose: The purpose of this prospective randomized single blinded split mouth study was to conduct a comparative evaluation of the efficacy of intranasal atomised spray formulation of Dexmedetomidine with Midazolam in patients undergoing surgical removal of bilaterally impacted mandibular third molars. Methods: This prospective study was conducted in twenty volunteers. Each volunteer underwent the surgical removal of an impacted mandibular third molar at two separate appointments at an interval of two weeks...
March 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29380523/dcd-donor-hemodynamics-as-predictor-of-outcome-after-kidney-transplantation
#15
H Peters-Sengers, J H E Houtzager, M B A Heemskerk, M M Idu, R C Minnee, R W Klaasen, S E Joor, J A M Hagenaars, P M Rebers, J J Homan van der Heide, J I Roodnat, F J Bemelman
Insufficient hemodynamics during agonal phase-i.e. the period between withdrawal of life-sustaining treatment and circulatory arrest-in Maastricht category III circulatory-death donors (DCD) potentially exacerbate ischemia/reperfusion injury. We included 409 Dutch adult recipients of DCD donor kidneys transplanted between 2006 and 2014. Peripheral oxygen saturation (SpO2-with pulse oximetry at the fingertip) and systolic blood pressure (SBP-with arterial catheter) were measured during agonal phase, and were dichotomized into minutes of SpO2>60% or SpO2<60%, and minutes of SBP>80 mmHg or SBP<80 mmHg...
January 30, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29377954/hypoxemia-in-patients-with-idiopathic-or-heritable-pulmonary-arterial-hypertension
#16
Ghaleb Khirfan, Tawfeq Naal, Batool Abuhalimeh, Jennie Newman, Gustavo A Heresi, Raed A Dweik, Adriano R Tonelli
BACKGROUND: The prevalence and prognostic implications of hypoxemia either at rest or during six-minute walk test (6MWT) in patients with idiopathic or heritable pulmonary arterial hypertension (IPAH or HPAH) have not been systemically studied. OBJECTIVES: We sought to determine the prevalence, phenotypic and prognostic implications of hypoxemia in patients with IPAH and HPAH. METHODS: Patients with IPAH or HPAH were identified from the Cleveland Clinic Pulmonary Hypertension Registry...
2018: PloS One
https://www.readbyqxmd.com/read/29377061/individualized-lung-recruitment-maneuver-guided-by-pulse-oximetry-in-anesthetized-patients-undergoing-laparoscopy-a-feasibility-study
#17
C Ferrando, G Tusman, F Suarez-Sipmann, I León, N Pozo, J Carbonell, J Puig, E Pastor, E Gracia, A Gutiérrez, G Aguilar, F J Belda, M Soro
BACKGROUND: We conducted this study to test whether pulse-oximetry hemoglobin saturation (SpO2 ) can personalize the implementation of an open-lung approach during laparoscopy. Thirty patients with SpO2  ≥ 97% on room-air before anesthesia were studied. After anesthesia and capnoperitoneum the FIO2 was reduced to 0.21. Those patients whose SpO2 decreased below 97% - an indication of shunt related to atelectasis - completed the following phases: (1) First recruitment maneuver (RM), until reaching lung's opening pressure, defined as the inspiratory pressure level yielding a SpO2 ≥ 97%; (2) decremental positive end-expiratory (PEEP) titration trial until reaching lung's closing pressure defined as the PEEP level yielding a SpO2  < 97%; (3) second RM and, (4) ongoing ventilation with PEEP adjusted above the detected closing pressure...
January 29, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29374469/perioperative-incidence-of-airway-obstructive-and-hypoxemic-events-in-patients-with-confirmed-or-suspected-sleep-apnea-a-prospective-randomized-pilot-study-comparing-propofol-remifentanil-and-sevoflurane-remifentanil-anesthesia
#18
Philipp Fassbender, Silja Bürgener, Ali Haddad, Marie-Therese Silvanus, Jürgen Peters
BACKGROUND: Obstructive sleep apnea (OSA) is a risk factor for perioperative complications but data on anesthesia regimen are scarce. METHODS: In patients with established or strongly suspected OSA, we assessed in a prospective, randomized design the effects on nocturnal apnea-hypopnea-index (AHI) and oxygen saturation (SpO 2 ) of propofol/remifentanil or sevoflurane/remifentanil based anesthesia. Patients were selected by a history for OSA and / or a positive STOP - questionnaire and received general anesthesia using remifentanil (12 μg/kg/h) combined either with propofol (4-6 mg/kg/h, n = 27) or sevoflurane (approx...
January 27, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29369000/cardiorespiratory-repercussions-according-to-the-abdominal-circumference-measurement-of-men-with-obstructive-respiratory-disorder-submitted-to-respiratory-physiotherapy
#19
Bruno Martinelli, Valéria Amorim Pires Di Lorenzo, Robison José Quitério, Alexandre Ricardo Pepe Ambrozin, Eduardo Aguilar Arca, Maurício Jamami
PURPOSE: To examine the effect of respiratory physiotherapy among men with obstructive respiratory disorder, in relation to abdominal circumference (AC). METHODS: Quasi-experimental study including 26 men split into two groups according to AC(cm): 1) < 102 (ACrisk-free); and 2) ≥ 102 (ACrisk). Heart rate variability (HRV), diastolic blood pressure (DBP), oxygen saturation (SpO2), FEV1/FVC, slow vital capacity (SVC), inspiratory capacity (IC), maximal inspiratory pressure (PImax), thoracoabdominal amplitude (AI) were measured: before (M1); 5 min after the physiotherapy (i...
January 25, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29367357/seesawing-end-tidal-carbon-dioxide-portent-of-critical-carbon-dioxide-embolism-in-retroperitoneoscopy
#20
Melvin Alex Abraham, Riya Jose, Mazhuvanchary Jacob Paul
An abrupt increase in end-tidal CO2 (EtCO2; from 35 to 58 mm Hg) followed by a sudden fall (to 18 mm Hg) was noted during retroperitoneoscopic adrenalectomy under general anaesthesia in a 23-year-old patient with adrenal hyperplasia. This was accompanied by hypotension (systolic blood pressure of 60 mm Hg), desaturation (88% SpO2) and ST depression (3.5 mm). The patient was resuscitated with fluids and vasopressor drugs and about 4 mL of air was aspirated through the central venous catheter, confirming the diagnosis of an intraoperative gas embolism...
January 23, 2018: BMJ Case Reports
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